1978 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

2010

Fixed-dose-rate gemcitabine: A viable first-line treatment option for advanced pancreatic and biliary tract cancer

Milella, M., Gelibter, A. J., Pino, M. S., Bossone, G., Marolla, P., Sperduti, I. & Cognetti, F., Feb 2010, In : The oncologist. 15, 2

Research output: Contribution to journalArticle

Impact of hormonal treatment duration in combination with radiotherapy for locally advanced prostate cancer: Meta-analysis of randomized trials

Cuppone, F., Bria, E., Giannarelli, D., Vaccaro, V., Milella, M., Nisticò, C., Ruggeri, E. M., Sperduti, I., Bracarda, S., Pinnarò, P., Lanzetta, G., Muti, P., Cognetti, F. & Carlini, P., Dec 9 2010, In : BMC Cancer. 10, 675.

Research output: Contribution to journalArticle

In situ protein expression of RRM1, ERCC1, and BRCA1 in metastatic breast cancer patients treated with gemcitabine-based chemotherapy

Metro, G., Zheng, Z., Fabi, A., Schell, M., Antoniani, B., Mottolese, M., Monteiro, A. N., Vici, P., Rivera, S. L., Boulware, D., Cognetti, F. & Bepler, G., 2010, In : Cancer Investigation. 28, 2, p. 172-180 9 p.

Research output: Contribution to journalArticle

Large randomized study of thymosin α 1, interferon alfa, or both in combination with dacarbazine in patients with metastatic melanoma

Maio, M., Mackiewicz, A., Testori, A., Trefzer, U., Ferraresi, V., Jassem, J., Garbe, C., Lesimple, T., Guillot, B., Gascon, P., Gilde, K., Camerini, R. & Cognetti, F., Apr 1 2010, In : Journal of Clinical Oncology. 28, 10, p. 1780-1787 8 p.

Research output: Contribution to journalArticle

Low-dose fotemustine for recurrent malignant glioma: A multicenter phase II study

Fabi, A., Metro, G., Vidiri, A., Lanzetta, G., Carosi, M., Telera, S., Maschio, M., Russillo, M., Sperduti, I., Carapella, C. M., Cognetti, F. & Pace, A., Nov 2010, In : Journal of Neuro-Oncology. 100, 2, p. 209-215 7 p.

Research output: Contribution to journalArticle

Magnitude of benefit of the addition of bevacizumab to first-line chemotherapy for metastatic colorectal cancer: Meta-analysis of randomized clinical trials

Loupakis, F., Bria, E., Vaccaro, V., Cuppone, F., Milella, M., Carlini, P., Cremolini, C., Salvatore, L., Falcone, A., Muti, P., Sperduti, I., Giannarelli, D. & Cognetti, F., May 26 2010, (Accepted/In press) In : Journal of Experimental and Clinical Cancer Research. p. 58 1 p.

Research output: Contribution to journalArticle

Phase II study of fixed dose rate gemcitabine as radiosensitizer for newly diagnosed glioblastoma multiforme

Metro, G., Fabi, A., Mirri, M. A., Vidiri, A., Pace, A., Carosi, M., Russillo, M., Maschio, M., Giannarelli, D., Pellegrini, D., Pompili, A., Cognetti, F. & Carapella, C. M., Jan 2010, In : Cancer Chemotherapy and Pharmacology. 65, 2, p. 391-397 7 p.

Research output: Contribution to journalArticle

Primary ovarian cancer cells are sensitive to the proaptotic effects of proteasome inhibitors

Pasquini, L., Petronelli, A., Petrucci, E., Saulle, E., Mariani, G., Scambia, G., Benedetti-Panici, P., Greggi, S., Cognetti, F. & Testa, U., 2010, In : International Journal of Oncology. 36, 3, p. 707-713 7 p.

Research output: Contribution to journalArticle

Time to first tumor progression as outcome predictor of a second trasuzumab-based therapy beyond progression in HER-2 positive metastatic breast cancer

Metro, G., Giannarelli, D., Gemma, D., Lanzetta, G., Ciccarese, M., Papaldo, P., Gamucci, T., Lorusso, V., Mottolese, M., Magnolfi, E., Cognetti, F. & Fabi, A., Jan 2010, In : Breast Journal. 16, 1, p. 66-72 7 p.

Research output: Contribution to journalArticle

Vitamin e neuroprotection for cisplatin neuropathy: A randomized, placebo-controlled trial

Pace, A., Giannarelli, D., Galiè, E., Savarese, A., Carpano, S., Della Giulia, M., Pozzi, A., Silvani, A., Gaviani, P., Scaioli, V., Jandolo, B., Bove, L. & Cognetti, F., Mar 2010, In : Neurology. 74, 9, p. 762-766 5 p.

Research output: Contribution to journalArticle

2009

A novel clinical prognostic score incorporating the number of resected lymph-nodes to predict recurrence and survival in non-small-cell lung cancer

Bria, E., Milella, M., Sperduti, I., Alessandrini, G., Visca, P., Corzani, F., Giannarelli, D., Cerasoli, V., Cuppone, F., Cecere, F. L., Marchetti, A., Sacco, R., Mucilli, F., Malatesta, S., Guetti, L., Vitale, L., Ceribelli, A., Rinaldi, M., Terzoli, E., Cognetti, F. & 1 others, Facciolo, F., Dec 2009, In : Lung Cancer. 66, 3, p. 365-371 7 p.

Research output: Contribution to journalArticle

Capecitabine and celecoxib as second-line treatment of advanced pancreatic and biliary tract cancers

Pino, M. S., Milella, M., Gelibter, A., Sperduti, I., De Marco, S., Nuzzo, C., Bria, E., Carpanese, L., Ruggeri, E. M., Carlini, P. & Cognetti, F., Mar 2009, In : Oncology. 76, 4, p. 254-261 8 p.

Research output: Contribution to journalArticle

Chemotherapy enhances vaccine-induced antitumor immunity in melanoma patients

Nisticò, P., Capone, I., Palermo, B., Bello, D. D., Ferraresi, V., Moschella, F., Aricò, E., Valentini, M., Bracci, L., Cognetti, F., Ciccarese, M., Vercillo, G., Roselli, M., Fossile, E., Tosti, M. E., Wang, E., Marincola, F., Imberti, L., Catricalà, C., Natali, P. G. & 2 others, Belardelli, F. & Proietti, E., Jan 1 2009, In : International Journal of Cancer. 124, 1, p. 130-139 10 p.

Research output: Contribution to journalArticle

Clinical implications of KRAS mutations in lung cancer patients treated with tyrosine kinase inhibitors: An important role for mutations in minor clones

Marchetti, A., Milella, M., Felicioni, L., Cappuzzo, F., Irtelli, L., Del Grammastro, M., Sciarrotta, M., Malatesta, S., Nuzzo, C., Finocchiaro, G., Perrucci, B., Carlone, D., Gelibter, A. J., Ceribelli, A., Mezzetti, A., Iacobelli, S., Cognetti, F. & Buttitta, F., Oct 2009, In : Neoplasia (United States). 11, 10, p. 1084-1092 9 p.

Research output: Contribution to journalArticle

Darbepoetin alfa and history of thromboembolic events

Ferretti, G., Felici, A. & Cognetti, F., Nov 20 2009, In : Journal of Clinical Oncology. 27, 33

Research output: Contribution to journalArticle

Does hormone treatment added to radiotherapy improve outcome in locally advanced prostate cancer? Meta-analysis of randomized trials

Bria, E., Cuppone, F., Giannarelli, D., Milella, M., Ruggeri, E. M., Sperduti, I., Pinnarò, P., Terzoli, E., Cognetti, F. & Carlini, P., Aug 1 2009, In : Cancer. 115, 15, p. 3446-3456 11 p.

Research output: Contribution to journalArticle

Growth-inhibitory and antiangiogenic activity of the MEK inhibitor PD0325901 in malignant melanoma with or without BRAF mutations

Ciuffreda, L., Del Bufalo, D., Desideri, M., Di Sanza, C., Stoppacciaro, A., Ricciardi, M. R., Chiaretti, S., Tavolaro, S., Benassi, B., Bellacosa, A., Foá, R., Tafuri, A., Cognetti, F., Anichini, A., Zupi, G. & Milella, M., Aug 2009, In : Neoplasia (United States). 11, 8, p. 720-731 12 p.

Research output: Contribution to journalArticle

High sensitivity of ovarian cancer cells to the synthetic triterpenoid CDDO-Imidazolide

Petronelli, A., Saulle, E., Pasquini, L., Petrucci, E., Mariani, G., Biffoni, M., Ferretti, G., Scambia, G., Benedetti-Panici, P., Greggi, S., Cognetti, F., Russo, M. A., Sporn, M. & Testa, U., Sep 18 2009, In : Cancer Letters. 282, 2, p. 214-228 15 p.

Research output: Contribution to journalArticle

Magnitude of benefit of adjuvant chemotherapy for non-small cell lung cancer: Meta-analysis of randomized clinical trials

Bria, E., Gralla, R. J., Raftopoulos, H., Cuppone, F., Milella, M., Sperduti, I., Carlini, P., Terzoli, E., Cognetti, F. & Giannarelli, D., Jan 2009, In : Lung Cancer. 63, 1, p. 50-57 8 p.

Research output: Contribution to journalArticle

Pharmacokinetics of gemcitabine at fixed-dose rate infusion in patients with normal and impaired hepatic function

Felici, A., Di Segni, S., Milella, M., Colantonio, S., Sperduti, I., Nuvoli, B., Contestabile, M., Sacconi, A., Zaratti, M., Citro, G. & Cognetti, F., 2009, In : Clinical Pharmacokinetics. 48, 2, p. 131-141 11 p.

Research output: Contribution to journalArticle

Pseudoprogression and MGMT status in glioblastoma patients: Implications in clinical practice

Fabi, A., Russillo, M., Metro, G., Vidiri, A., Di Giovanni, S. & Cognetti, F., Jul 2009, In : Anticancer Research. 29, 7, p. 2607-2610 4 p.

Research output: Contribution to journalArticle

Subjective versus objective risk in genetic counseling for hereditary breast and/or ovarian cancers

Caruso, A., Vigna, C., Marozzo, B., Sega, F. M., Sperduti, I., Cognetti, F. & Savarese, A., 2009, In : Journal of Experimental and Clinical Cancer Research. 28, 1, 157.

Research output: Contribution to journalArticle

Targeting targeted agents: Open issues for clinical trial design

Bria, E., Di Maio, M., Carlini, P., Cuppone, F., Giannarelli, D., Cognetti, F. & Milella, M., 2009, In : Journal of Experimental and Clinical Cancer Research. 28, 1, 66.

Research output: Contribution to journalArticle

Trastuzumab plus weekly epirubicin and paclitaxel for locally advanced and metastatic breast cancer: Preliminary results of a feasibility-phase II study aimed at cardiotoxicity

Nisticò, C., Bria, E., Vaccaro, V., Cuppone, F., Fornier, M., Sperduti, I., Carpino, A., Lzzo, F., Tropea, F., Cognetti, F. & Terzoli, E., Feb 2009, In : Anti-Cancer Drugs. 20, 2, p. 109-114 6 p.

Research output: Contribution to journalArticle

Treatment of recurrent malignant gliomas with fotemustine monotherapy: Impact of dose and correlation with MGMT promoter methylation

Fabi, A., Metro, G., Russillo, M., Vidiri, A., Carapella, M. C., Maschio, M., Cognetti, F., Jandolo, B., Mirri, M., Sperduti, I., Telera, S., Carosi, M. & Pace, A., Mar 31 2009, In : BMC Cancer. 9, 101.

Research output: Contribution to journalArticle

2008

A phase II study of biweekly paclitaxel (P) and gemcitabine (G), followed by maintenance weekly paclitaxel in elderly patients with advanced non-small cell lung cancer (NSCLC)

Pino, M. S., Gamucci, T., Mansueto, G., Trapasso, T., Narducci, F., Giampaolo, M. A., Fariello, A. M., Sperduti, I., Ceribelli, A. & Cognetti, F., Jun 2008, In : Lung Cancer. 60, 3, p. 381-386 6 p.

Research output: Contribution to journalArticle

Bevacizumab: One treatment for all the seasons? [5]

Gelibter, A. J., Zeuli, M., Cognetti, F. & Di Segni, S., Jan 20 2008, In : Journal of Clinical Oncology. 26, 3, p. 511 1 p.

Research output: Contribution to journalArticle

Carboplatin and pegylated liposomal doxorubicin for advanced ovarian cancer: Preliminary activity results of the MITO-2 phase III trial

Pignata, S., Scambia, G., Savarese, A., Breda, E., Sorio, R., Pisano, C., Lorusso, D., Cognetti, F., Vernaglia Lombardi, A., Gebbia, V., Scollo, P., Morabito, A., Signoriello, G. & Perrone, F., Dec 2008, In : Oncology. 76, 1, p. 49-54 6 p.

Research output: Contribution to journalArticle

COX-2 targeting in cancer: A new beginning?

Milella, M., Metro, G., Gelibter, A., Pino, S. M., Cognetti, F. & Fabi, A., Jun 2008, In : Annals of Oncology. 19, 6, p. 1209-1210 2 p.

Research output: Contribution to journalArticle

Do adjuvant aromatase inhibitors increase the cardiovascular risk in postmenopausal women with early breast cancer? Meta-analysis of randomized trials

Cuppone, F., Bria, E., Verma, S., Pritchard, K. I., Gandhi, S., Carlini, P., Milella, M., Nisticò, C., Terzoli, E., Cognetti, F. & Giannarelli, D., Jan 15 2008, In : Cancer. 112, 2, p. 260-267 8 p.

Research output: Contribution to journalArticle

Do HER-2 positive metastatic breast cancer patients benefit from the use of trastuzumab beyond disease progression? A mono-institutional experience and systematic review of observational studies

Fabi, A., Metro, G., Ferretti, G., Giannarelli, D., Di Cosimo, S., Papaldo, P., Mottolese, M., Carlini, P., Felici, A., Russillo, M. & Cognetti, F., Oct 2008, In : Breast. 17, 5, p. 499-505 7 p.

Research output: Contribution to journalArticle

Fixed dose-rate gemcitabine as radiosensitizer for newly diagnosed glioblastoma: A dose-finding study

Fabi, A., Mirri, A., Felici, A., Vidiri, A., Pace, A., Occhipinti, E., Cognetti, F., Arcangeli, G., Iandolo, B., Carosi, M. A., Metro, G. & Carapella, C. M., Mar 2008, In : Journal of Neuro-Oncology. 87, 1, p. 79-84 6 p.

Research output: Contribution to journalArticle

Gemcitabine at fixed dose-rate in patients with advanced soft tissue sarcomas: A mono-institutional phase II study

Ferraresi, V., Ciccarese, M., Cercato, M. C., Nuzzo, C., Zeuli, M., Di Filippo, F., Giannarelli, D. & Cognetti, F., Dec 2008, In : Cancer Chemotherapy and Pharmacology. 63, 1, p. 149-155 7 p.

Research output: Contribution to journalArticle

HER2 and response to paclitaxel in node-positive breast cancer [10]

Ferretti, G., Felici, A. & Cognetti, F., Jan 10 2008, In : New England Journal of Medicine. 358, 2, p. 197 1 p.

Research output: Contribution to journalArticle

Impact of celecoxib on capecitabine tolerability and activity in pretreated metastatic breast cancer: Results of a phase II study with biomarker evaluation

Fabi, A., Metro, G., Papaldo, P., Mottolese, M., Melucci, E., Carlini, P., Sperduti, I., Russillo, M., Gelibter, A., Ferretti, G., Tomao, S., Milella, M. & Cognetti, F., Sep 2008, In : Cancer Chemotherapy and Pharmacology. 62, 4, p. 717-725 9 p.

Research output: Contribution to journalArticle

Multicentric, randomized phase III trial of two different adjuvant chemotherapy regimens plus three versus twelve months of trastuzumab in patients with HER2- positive breast cancer (Short-HER Trial; NCT00629278)

Guarneri, V., Frassoldati, A., Bruzzi, P., D'Amico, R., Belfiglio, M., Molino, A., Bertetto, O., Cascinu, S., Cognetti, F., Di Leo, A., Pronzato, P., Crinó, L., Agostara, B. & Conte, P., Oct 1 2008, In : Clinical Breast Cancer. 8, 5, p. 453-456 4 p.

Research output: Contribution to journalArticle

Nuclear and cytoplasmic cellular distribution of survivin as survival predictor in resected non-small-cell lung cancer

Bria, E., Visca, P., Novelli, F., Casini, B., Diodoro, M. G., Perrone-Donnorso, R., Botti, C., Sperduti, I., Facciolo, F., Milella, M., Cecere, F. L., Cognetti, F. & Mottolese, M., May 2008, In : European Journal of Surgical Oncology. 34, 5, p. 593-598 6 p.

Research output: Contribution to journalArticle

Oral ondansetron is highly active as rescue antiemetic treatment for moderately emetogenic chemotherapy: Results of a randomized phase II study

Fabi, A., Ciccarese, M., Metro, G., Savarese, A., Giannarelli, D., Nuzzo, C. M., Russillo, M., Sperduti, I., Carbone, I., Bria, E. & Cognetti, F., Dec 2008, In : Supportive Care in Cancer. 16, 12, p. 1375-1380 6 p.

Research output: Contribution to journalArticle

P53 and bcl-2 in colorectal cancer arising in patients under 40 years of age: Distribution and prognostic relevance

Torsello, A., Garufi, C., Cosimelli, M., Diodoro, M. G., Zeuli, M., Vanni, B., Campanella, C., D'Angelo, C., Sperduti, I., Donnorso, R. P., Cognetti, F., Terzoli, E. & Mottolese, M., Jun 2008, In : European Journal of Cancer. 44, 9, p. 1217-1222 6 p.

Research output: Contribution to journalArticle

Taxanes and gemcitabine doublets in the management of HER-2 negative metastatic breast cancer: Towards optimization of association and schedule

Metro, G., Fabi, A., Russillo, M., Papaldo, P., De Laurentiis, M., Ferretti, G., Pellegrini, D., Nuzzo, C., Graziano, V., Vici, P., Introna, M., Felici, A., Cognetti, F. & Carlini, P., Mar 2008, In : Anticancer Research. 28, 2 B, p. 1245-1258 14 p.

Research output: Contribution to journalArticle

Taxanes as primary chemotherapy for early breast cancer: Meta-analysis of randomized trials

Cuppone, F., Bria, E., Carlini, P., Milella, M., Felici, A., Sperduti, I., Nisticò, C., Terzoli, E., Cognetti, F. & Giannarelli, D., Jul 15 2008, In : Cancer. 113, 2, p. 238-246 9 p.

Research output: Contribution to journalArticle

Trastuzumab cardiotoxicity: Biological hypotheses and clinical open issues

Bria, E., Cuppone, F., Milella, M., Verma, S., Carlini, P., Nisticò, C., Vaccaro, V., Rossi, A., Tonini, G., Cognetti, F. & Terzoli, E., Dec 2008, In : Expert Opinion on Biological Therapy. 8, 12, p. 1963-1971 9 p.

Research output: Contribution to journalArticle

Unexpected clinical outcome in a patient with liver and brain metastasis from melanoma

Nuzzo, C., Zeuli, M., Ferraresi, V., Ciccarese, M., Pelligrini, D. & Cognetti, F., Mar 2008, In : Anticancer Research. 28, 2 B, p. 1429-1431 3 p.

Research output: Contribution to journalArticle

2007

Adjuvant Chemotherapy for Bladder Cancer: The Chance for Meta-analyses Comparison

Bria, E., Ruggeri, E. M., Pollera, C. F., Terzoli, E., Cognetti, F. & Giannarelli, D., Feb 2007, In : European Urology. 51, 2, p. 576-577 2 p.

Research output: Contribution to journalArticle

Adjuvant chemotherapy for non-small cell lung cancer

Bria, E., Cuppone, F., Cecere, F. L., Milella, M., Nisticò, C., Cognetti, F. & Terzoli, E., May 2007, In : Journal of Thoracic Oncology. 2, 5 SUPPL.1

Research output: Contribution to journalArticle

Antitumor effects of clinical dosing regimens of bisphosphonates in experimental breast cancer bone metastasis

Ferretti, G., Fabi, A., Carlini, P., Papaldo, P., Felici, A. & Cognetti, F., Jul 2007, In : Bone. 41, 1, p. 155-156 2 p.

Research output: Contribution to journalArticle

A phase II trial of gefitinib in combination with capecitabine and oxaliplatin as first-line chemotherapy in patients with advanced colorectal cancer

Geulibter, A. J., Gamucci, T., Pollera, C. F., Di Costanzo, F., Nuzzo, C., Gabriele, A., Signorelli, C., Gasperoni, S., Ferraresi, V., Giannarelli, D., Cognetti, F. & Zeuli, M., Sep 2007, In : Current Medical Research and Opinion. 23, 9, p. 2117-2123 7 p.

Research output: Contribution to journalArticle

Aromatase inhibitors in post-menopausal metastatic breast carcinoma

Carlini, P., Bria, E., Giannarelli, D., Felici, A., Papaldo, P., Fabi, A., Ruggeri, E. M., Milella, M., Nuzzo, C., Cecere, F. L., Gelibter, A., Pino, M. S., Nisticò, C., Cuppone, F., Metro, G., Terzoli, E., Cognetti, F. & Ferretti, G., Jul 2007, In : Expert Opinion on Investigational Drugs. 16, 7, p. 1023-1036 14 p.

Research output: Contribution to journalArticle