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Research Output

2019

Calcium regulates HCC proliferation as well as EGFR recycling/degradation and could be a new therapeutic target in HCC

Modica, T. M. E., Dituri, F., Mancarella, S., Pisano, C., Fabregat, I. & Giannelli, G., Oct 2019, In : Cancers. 11, 10, 1588.

Research output: Contribution to journalArticle

Open Access

Epigenetic upregulation and functional role of the mitochondrial aspartate/glutamate carrier isoform 1 in hepatocellular carcinoma

Infantino, V., Dituri, F., Convertini, P., Santarsiero, A., Palmieri, F., Todisco, S., Mancarella, S., Giannelli, G. & Iacobazzi, V., Jan 2019, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1865, 1, p. 38-47 10 p.

Research output: Contribution to journalArticle

Validation of hepatocellular carcinoma experimental models for TGF-β promoting tumor progression

Mancarella, S., Krol, S., Crovace, A., Leporatti, S., Dituri, F., Frusciante, M. & Giannelli, G., Oct 2019, In : Cancers. 11, 10, 1510.

Research output: Contribution to journalReview article

Open Access
2018

Galunisertib suppresses the staminal phenotype in hepatocellular carcinoma by modulating CD44 expression

Rani, B., Malfettone, A., Dituri, F., Soukupova, J., Lupo, L., Mancarella, S., Fabregat, I. & Giannelli, G., Mar 7 2018, In : Cell Death and Disease. 9, 3, p. 373 12 p.

Research output: Contribution to journalArticle

TGF-β and the Tissue Microenvironment: Relevance in Fibrosis and Cancer

Caja, L., Dituri, F., Mancarella, S., Caballero-Diaz, D., Moustakas, A., Giannelli, G. & Fabregat, I., Apr 26 2018, In : International Journal of Molecular Sciences. 19, 5, p. 1294 26 p.

Research output: Contribution to journalReview article

TGF-β as Multifaceted Orchestrator in HCC Progression: Signaling, EMT, Immune Microenvironment, and Novel Therapeutic Perspectives

Dituri, F., Mancarella, S., Cigliano, A., Chieti, A. & Giannelli, G., Dec 26 2018, In : Seminars in Liver Disease. p. 1-17 17 p.

Research output: Contribution to journalArticle

2017

Microenvironment inflammatory infiltrate drives growth speed and outcome of hepatocellular carcinoma: a prospective clinical study

Critelli, R., Milosa, F., Faillaci, F., Condello, R., Turola, E., Marzi, L., Lei, B., Dituri, F., Andreani, S., Sighinolfi, P., Manni, P., Maiorana, A., Caporali, C., di Benedetto, F., Del Buono, M., De Maria, N., Schepis, F., Martinez-Chantar, M-L., Giannelli, G. & Villa, E., Aug 24 2017, In : Cell Death and Disease. 8, 8, p. e3017

Research output: Contribution to journalArticle

NGS-based transcriptome profiling reveals biomarkers for companion diagnostics of the TGF-β receptor blocker galunisertib in HCC

Cao, Y., Agarwal, R., Dituri, F., Lupo, L., Trerotoli, P., Mancarella, S., Winter, P. & Giannelli, G., Feb 23 2017, In : Cell Death and Disease. 8, 2, p. e2634

Research output: Contribution to journalArticle

Precision medicine for hepatocelluar carcinoma using molecular pattern diagnostics: results from a preclinical pilot study

Agarwal, R., Cao, Y., Hoffmeier, K., Krezdorn, N., Jost, L., Meisel, A. R., Jüngling, R., Dituri, F., Mancarella, S., Rotter, B., Winter, P. & Giannelli, G., Jun 8 2017, In : Cell Death and Disease. 8, 6, p. e2867

Research output: Contribution to journalArticle

2016

Hepatic stellate cells induce hepatocellular carcinoma cell resistance to sorafenib through the laminin-332/α3 integrin axis recovery of focal adhesion kinase ubiquitination

Azzariti, A., Mancarella, S., Porcelli, L., Quatrale, A. E., Caligiuri, A., Lupo, L., Dituri, F. & Giannelli, G., Dec 2016, In : Hepatology. 64, 6, p. 2103-2117 15 p.

Research output: Contribution to journalArticle