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1979 …2020
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Research Output 1979 2020

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2020

Microarray expression studies on bone marrow of patients with Shwachman-Diamond syndrome in relation to deletion of the long arm of chromosome 20, other chromosome anomalies or normal karyotype

Khan, A. W., Minelli, A., Frattini, A., Montalbano, G., Bogni, A., Fabbri, M., Porta, G., Acquati, F., Pinto, R. M., Bergami, E., Mura, R., Pegoraro, A., Cesaro, S., Cipolli, M., Zecca, M., Danesino, C., Locatelli, F., Maserati, E., Pasquali, F. & Valli, R., Jan 2 2020, In : Molecular Cytogenetics. 13, 1, 1.

Research output: Contribution to journalArticle

Open Access
2019

A novel disorder involving dyshematopoiesis, inflammation, and HLH due to aberrant CDC42 function

Lam, M. T., Coppola, S., Krumbach, O. H. F., Prencipe, G., Insalaco, A., Cifaldi, C., Brigida, I., Zara, E., Scala, S., Di Cesare, S., Martinelli, S., Di Rocco, M., Pascarella, A., Niceta, M., Pantaleoni, F., Ciolfi, A., Netter, P., Carisey, A. F., Diehl, M., Akbarzadeh, M. & 30 others, Conti, F., Merli, P., Pastore, A., Levi Mortera, S., Camerini, S., Farina, L., Buchholzer, M., Pannone, L., Cao, T. N., Coban-Akdemir, Z. H., Jhangiani, S. N., Muzny, D. M., Gibbs, R. A., Basso-Ricci, L., Chiriaco, M., Dvorsky, R., Putignani, L., Carsetti, R., Janning, P., Stray-Pedersen, A., Erichsen, H. C., Rosti, V., Bracaglia, C., Palma, P., Finocchi, A., Locatelli, F., Cancrini, C., Aiuti, A., De Benedetti, F. & Tartaglia, M., Dec 2 2019, In : The Journal of experimental medicine. 216, 12, p. 2778-2799 22 p.

Research output: Contribution to journalArticle

Open Access

Association between adenovirus viral load and mortality in pediatric allo-HCT recipients: the multinational AdVance study

Zecca, M., Wynn, R., Dalle, J. H., Feuchtinger, T., Vainorius, E., Brundage, T. M., Chandak, A., Mozaffari, E., Nichols, G. & Locatelli, F., Jan 1 2019, In : Bone Marrow Transplantation.

Research output: Contribution to journalArticle

Open Access
Viral Load
Adenoviridae
Pediatrics
Viremia
Mortality

Association between adenovirus viral load and mortality in pediatric allo-HCT recipients: the multinational AdVance study

Zecca, M., Wynn, R., Dalle, J-H., Feuchtinger, T., Vainorius, E., Brundage, T. M., Chandak, A., Mozaffari, E., Nichols, G. & Locatelli, F., Feb 25 2019, In : Bone Marrow Transplantation.

Research output: Contribution to journalArticle

Viral Load
Adenoviridae
Pediatrics
Mortality
Viremia
Immunotherapy
B-Lymphocytes
Therapeutics
Investigational Therapies
Lymphopenia
Cannabinoid Receptor CB2
pathogenesis
Idiopathic Thrombocytopenic Purpura
Cell death
Immunosuppressive Agents

Characterization of the novel HLA-DPA1*02:15 allele by sequencing-based typing

Blouin, L., Andreani, M., Locatelli, F., Guidicelli, G. & Visentin, J., May 8 2019, In : HLA.

Research output: Contribution to journalArticle

Alleles
Codon
Exons
Nucleotides
HLA-DPA1 antigen

Clinical, Immunological, and Molecular Features of Typical and Atypical Severe Combined Immunodeficiency: Report of the Italian Primary Immunodeficiency Network

Cirillo, E., Cancrini, C., Azzari, C., Martino, S., Martire, B., Pession, A., Tommasini, A., Naviglio, S., Finocchi, A., Consolini, R., Pierani, P., D'Alba, I., Putti, M. C., Marzollo, A., Giardino, G., Prencipe, R., Esposito, F., Grasso, F., Scarselli, A., Di Matteo, G. & 15 others, Attardi, E., Ricci, S., Montin, D., Specchia, F., Barzaghi, F., Cicalese, M. P., Quaremba, G., Lougaris, V., Giliani, S., Locatelli, F., Rossi, P., Aiuti, A., Badolato, R., Plebani, A. & Pignata, C., 2019, In : Frontiers in Immunology. 10, p. 1908

Research output: Contribution to journalArticle

Severe Combined Immunodeficiency
Phenotype
Genetic Heterogeneity
Genetic Association Studies
Cell- and Tissue-Based Therapy

Clinical applications of donor lymphocyte infusion from an HLA-haploidentical donor: consensus recommendations from the acute leukemia working party of the EBMT

Dholaria, B., Savani, B. N., Labopin, M., Luznik, L., Ruggeri, A., Mielke, S., Al Malki, M. M., Kongtim, P., Fuchs, E., Huang, X-J., Locatelli, F., Aversa, F., Castagna, L., Bacigalupo, A., Martelli, M., Blaise, D., Ben Soussan, P., Arnault, Y., Handgretinger, R., Roy, D-C. & 19 others, O'Donnell, P., Bashey, A., Solomon, S., Romee, R., Lewalle, P., Gayoso, J., Maschan, M., Lazarus, H. M., Ballen, K., Giebel, S., Baron, F., Ciceri, F., Esteve, J., Gorin, N-C., Spyridonidis, A., Schmid, C., Ciurea, S. O., Nagler, A. & Mohty, M., Sep 19 2019, In : Haematologica.

Research output: Contribution to journalArticle

Leukemia
Tissue Donors
Lymphocytes
Cell Transplantation
Transplantation

Clofarabine and Treosulfan as Conditioning for Matched Related and Unrelated Hematopoietic Stem Cell Transplantation: Results from the Clo3o Phase II Trial

Peccatori, J., Mastaglio, S., Giglio, F., Greco, R., Crocchiolo, R., Patriarca, F., Forno, B., Deola, S., Assanelli, A., Lupo Stanghellini, M. T., Marcatti, M., Zecca, M., Cortelazzo, S., Fanin, R., Fagioli, F., Locatelli, F. & Ciceri, F., Jan 1 2019, (Accepted/In press) In : Biology of Blood and Marrow Transplantation.

Research output: Contribution to journalArticle

Corrigendum: Targeted NGS Platforms for Genetic Screening and Gene Discovery in Primary Immunodeficiencies

Cifaldi, C., Brigida, I., Barzaghi, F., Zoccolillo, M., Ferradini, V., Petricone, D., Cicalese, M. P., Lazarevic, D., Cittaro, D., Omrani, M., Attardi, E., Conti, F., Scarselli, A., Chiriaco, M., Di Cesare, S., Licciardi, F., Davide, M., Ferrua, F., Canessa, C., Pignata, C. & 20 others, Giliani, S., Ferrari, S., Fousteri, G., Barera, G., Merli, P., Palma, P., Cesaro, S., Gattorno, M., Trizzino, A., Moschese, V., Chini, L., Villa, A., Azzari, C., Finocchi, A., Locatelli, F., Rossi, P., Sangiuolo, F., Aiuti, A., Cancrini, C. & Di Matteo, G., 2019, In : Frontiers in Immunology. 10, p. 1184

Research output: Contribution to journalArticle

Genetic Testing
Genetic Association Studies
corrigendum

Durable remissions in TCF3-HLF positive acute lymphoblastic leukemia with blinatumomab and stem cell transplantation

Mouttet, B., Vinti, L., Ancliff, P., Bodmer, N., Brethon, B., Cario, G., Chen-Santel, C., Elitzur, S., Hazar, V., Kunz, J., Möricke, A., Stein, J., Vora, A., Yaman, Y., Schrappe, M., Sanak, S., Baruchel, A., Locatelli, F., von Stackelberg, A., Stanulla, M. & 1 others, Bourquin, J-P., Feb 14 2019, In : Haematologica.

Research output: Contribution to journalArticle

Dynamic inosinome profiles reveal novel patient stratification and gender-specific differences in glioblastoma

Silvestris, D. A., Picardi, E., Cesarini, V., Fosso, B., Mangraviti, N., Massimi, L., Martini, M., Pesole, G., Locatelli, F. & Gallo, A., Feb 13 2019, In : Genome Biology. 20, 1, p. 33

Research output: Contribution to journalArticle

Glioblastoma
RNA
gender
stratification
RNA Editing

Early gut microbiota signature of aGvHD in children given allogeneic hematopoietic cell transplantation for hematological disorders

Biagi, E., Zama, D., Rampelli, S., Turroni, S., Brigidi, P., Consolandi, C., Severgnini, M., Picotti, E., Gasperini, P., Merli, P., Decembrino, N., Zecca, M., Cesaro, S., Faraci, M., Prete, A., Locatelli, F., Pession, A., Candela, M. & Masetti, R., Mar 7 2019, In : BMC Medical Genomics. 12, 1

Research output: Contribution to journalArticle

Hematopoietic Stem Cell Transplantation
Cell Transplantation
Graft vs Host Disease
Fusobacterium
Pediatrics

Early gut microbiota signature of aGvHD in children given allogeneic hematopoietic cell transplantation for hematological disorders

Biagi, E., Zama, D., Rampelli, S., Turroni, S., Brigidi, P., Consolandi, C., Severgnini, M., Picotti, E., Gasperini, P., Merli, P., Decembrino, N., Zecca, M., Cesaro, S., Faraci, M., Prete, A., Locatelli, F., Pession, A., Candela, M. & Masetti, R., Mar 7 2019, In : BMC Medical Genomics. 12, 1, 49.

Research output: Contribution to journalArticle

Open Access
Hematopoietic Stem Cell Transplantation
Cell Transplantation
Graft vs Host Disease
Fusobacterium
Pediatrics

Eomesodermin controls a unique differentiation program in human IL-10 and IFN-γ coproducing regulatory T cells

Gruarin, P., Maglie, S., De Simone, M., Häringer, B., Vasco, C., Ranzani, V., Bosotti, R., Noddings, J. S., Larghi, P., Facciotti, F., Sarnicola, M. L., Martinovic, M., Crosti, M., Moro, M., Rossi, R. L., Bernardo, M. E., Caprioli, F., Locatelli, F., Rossetti, G., Abrignani, S. & 2 others, Pagani, M. & Geginat, J., 2019, In : European Journal of Immunology. 49, 1, p. 96-111

Research output: Contribution to journalArticle

Interleukin-10
T-Lymphocyte Subsets
Regulatory T-Lymphocytes
CD40 Ligand
Interleukin-27

ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP

Bufalieri, F., Infante, P., Bernardi, F., Caimano, M., Romania, P., Moretti, M., Lospinoso Severini, L., Talbot, J., Melaiu, O., Tanori, M., Di Magno, L., Bellavia, D., Capalbo, C., Puget, S., De Smaele, E., Canettieri, G., Guardavaccaro, D., Busino, L., Peschiaroli, A., Pazzaglia, S. & 7 others, Giannini, G., Melino, G., Locatelli, F., Gulino, A., Ayrault, O., Fruci, D. & Di Marcotullio, L., Jul 24 2019, In : Nature Communications. 10, 1, p. 3304

Research output: Contribution to journalArticle

endoplasmic reticulum
Aminopeptidases
Endoplasmic Reticulum
Carcinogenesis
degradation

Genomic subtyping and therapeutic targeting of acute erythroleukemia

Iacobucci, I., Wen, J., Meggendorfer, M., Choi, J. K., Shi, L., Pounds, S. B., Carmichael, C. L., Masih, K. E., Morris, S. M., Lindsley, R. C., Janke, L. J., Alexander, T. B., Song, G., Qu, C., Li, Y., Payne-Turner, D., Tomizawa, D., Kiyokawa, N., Valentine, M., Valentine, V. & 28 others, Basso, G., Locatelli, F., Enemark, E. J., Kham, S. K. Y., Yeoh, A. E. J., Ma, X., Zhou, X., Sioson, E., Rusch, M., Ries, R. E., Stieglitz, E., Hunger, S. P., Wei, A. H., To, L. B., Lewis, I. D., D'Andrea, R. J., Kile, B. T., Brown, A. L., Scott, H. S., Hahn, C. N., Marlton, P., Pei, D., Cheng, C., Loh, M. L., Ebert, B. L., Meshinchi, S., Haferlach, T. & Mullighan, C. G., Apr 2019, In : Nature Genetics. 51, 4, p. 694-704 11 p.

Research output: Contribution to journalArticle

Leukemia
Myeloid Leukemia
Mutation
Therapeutics
Acute erythroleukemia

Gonadal function after Busulfan compared to Treosulfan in children and adolescents undergoing allogeneic hematopoietic stem cell transplantation. On Behalf of the Pediatric and Transplant Complications Working Parties of EBMT

Faraci, M., Diesch, T., Labopin, M., Dalissier, A., Lankester, A., Gennery, A., Sundin, M., Uckan-Cetinkaya, D., Bierings, M., Peters, A. M. J., Garwer, M., Schulz, A., Michel, G., Giorgiani, G., Gruhn, B., Locatelli, F., Giardino, S., Uyttebroeck, A., Rialland, F., Itäla-Remes, M. & 15 others, Dreger, P., Shaw, P. J., Bordon, V., Schlegel, P. G., Mellgren, K., Moraleda, J. M., Patrick, K., Schneider, P., Jubert, C., Lawitschka, A., Salooja, N., Basak, G. W., Corbaciuoglu, S., Duarte, R. & Bader, P., May 10 2019, In : Biology of Blood and Marrow Transplantation.

Research output: Contribution to journalArticle

treosulfan
Busulfan
Hematopoietic Stem Cell Transplantation
Transplantation
Bone Marrow

Gonadal Function after Busulfan Compared with Treosulfan in Children and Adolescents Undergoing Allogeneic Hematopoietic Stem Cell Transplant

Faraci, M., Diesch, T., Labopin, M., Dalissier, A., Lankester, A., Gennery, A., Sundin, M., Uckan-Cetinkaya, D., Bierings, M., Peters, A. M. J., Garwer, M., Schulz, A., Michel, G., Giorgiani, G., Gruhn, B., Locatelli, F., Giardino, S., Uyttebroeck, A., Rialland, F., Itäla-Remes, M. & 15 others, Dreger, P., Shaw, P. J., Bordon, V., Schlegel, P. G., Mellgren, K., Moraleda, J. M., Patrick, K., Schneider, P., Jubert, C., Lawitschka, A., Salooja, N., Basak, G. W., Corbacioglu, S., Duarte, R. & Bader, P., 2019, In : Biology of Blood and Marrow Transplantation.

Research output: Contribution to journalArticle

Health-Related Quality of Life and Emotional Difficulties in Chronic Granulomatous Disease: Data on Adult and Pediatric Patients from Italian Network for Primary Immunodeficiency (IPINet)

Pulvirenti, F., Sangerardi, M., Plebani, A., Soresina, A., Finocchi, A., Pignata, C., Cirillo, E., Trizzino, A., Aiuti, A., Migliavacca, M., Locatelli, F., Bertaina, A., Naviglio, S., Carrabba, M., De Carli, M., Barbaro, M. G. F., Gattorno, M., Quinti, I. & Martire, B., Jan 1 2019, (Accepted/In press) In : Journal of Clinical Immunology.

Research output: Contribution to journalArticle

Wilms Tumor
Cell Transplantation
Transplantation
Bone Marrow
Drug Therapy
Natural Killer Cells
Transfection
Adoptive Immunotherapy
Neoplasms
Electroporation

HUWE1 controls MCL1 stability to unleash AMBRA1-induced mitophagy

Strappazzon, F., Di Rita, A., Peschiaroli, A., Leoncini, P. P., Locatelli, F., Melino, G. & Cecconi, F., Aug 21 2019, In : Cell Death and Differentiation.

Research output: Contribution to journalArticle

Mitochondrial Degradation
Glycogen Synthase Kinase 3
Mitochondria
Ubiquitin-Protein Ligases
Proto-Oncogene Proteins c-bcl-2
Mitochondrial Degradation
Glycogen Synthase Kinase 3
Mitochondria
Ubiquitin-Protein Ligases
Proto-Oncogene Proteins c-bcl-2

Identification of the novel HLA-A*01:289 allele in an Italian patient

Galluccio, T., Locatelli, F., Troiano, M., Testa, G. & Andreani, M., Jun 2019, In : HLA. 93, 6, p. 484-485 2 p.

Research output: Contribution to journalArticle

HLA-A Antigens
Alleles
Exons
Nucleotides
Survivors
Registries
Cause of Death
Mortality
Neoplasms

Outcome of Infants Younger Than 1 Year With Acute Lymphoblastic Leukemia Treated With the Interfant-06 Protocol: Results From an International Phase III Randomized Study

Pieters, R., De Lorenzo, P., Ancliffe, P., Aversa, L. A., Brethon, B., Biondi, A., Campbell, M., Escherich, G., Ferster, A., Gardner, R. A., Kotecha, R. S., Lausen, B., Li, C. K., Locatelli, F., Attarbaschi, A., Peters, C., Rubnitz, J. E., Silverman, L. B., Stary, J., Szczepanski, T. & 3 others, Vora, A., Schrappe, M. & Valsecchi, M. G., Jul 8 2019, In : Journal of clinical oncology : official journal of the American Society of Clinical Oncology. p. JCO1900261

Research output: Contribution to journalArticle

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Disease-Free Survival
Etoposide
Stem Cell Transplantation
Mitoxantrone

Outcomes and Treatment Strategies for Autoimmunity and Hyperinflammation in Patients with RAG Deficiency

Farmer, J. R., Foldvari, Z., Ujhazi, B., De Ravin, S. S., Chen, K., Bleesing, J. J. H., Schuetz, C., Al-Herz, W., Abraham, R. S., Joshi, A. Y., Costa-Carvalho, B. T., Buchbinder, D., Booth, C., Reiff, A., Ferguson, P. J., Aghamohammadi, A., Abolhassani, H., Puck, J. M., Adeli, M., Cancrini, C. & 55 others, Palma, P., Bertaina, A., Locatelli, F., Di Matteo, G., Geha, R. S., Kanariou, M. G., Lycopoulou, L., Tzanoudaki, M., Sleasman, J. W., Parikh, S., Pinero, G., Fischer, B. M., Dbaibo, G., Unal, E., Patiroglu, T., Karakukcu, M., Al-Saad, K. K., Dilley, M. A., Pai, S-Y., Dutmer, C. M., Gelfand, E. W., Geier, C. B., Eibl, M. M., Wolf, H. M., Henderson, L. A., Hazen, M. M., Bonfim, C., Wolska-Kuśnierz, B., Butte, M. J., Hernandez, J. D., Nicholas, S. K., Stepensky, P., Chandrakasan, S., Miano, M., Westermann-Clark, E., Goda, V., Kriván, G., Holland, S. M., Fadugba, O., Henrickson, S. E., Ozen, A., Karakoc-Aydiner, E., Baris, S., Kiykim, A., Bredius, R., Hoeger, B., Boztug, K., Pashchenko, O., Neven, B., Moshous, D., Villartay, J-P. D., Bousfiha, A. A., Hill, H. R., Notarangelo, L. D. & Walter, J. E., Mar 12 2019, In : Journal of Allergy and Clinical Immunology: In Practice.

Research output: Contribution to journalArticle

Autoimmunity
Genetic Recombination
Idiopathic Thrombocytopenic Purpura
Genes
Neutropenia

Phase I dose-escalation study of volasertib in pediatric patients with acute leukemia or advanced solid tumors

Doz, F., Locatelli, F., Baruchel, A., Blin, N., De Moerloose, B., Frappaz, D., Dworzak, M., Fischer, M., Stary, J., Fuertig, R., Riemann, K., Taube, T. & Reinhardt, D., Jul 5 2019, In : Pediatric Blood and Cancer. p. e27900

Research output: Contribution to journalArticle

Leukemia
Pediatrics
Maximum Tolerated Dose
Neoplasms
Pharmacokinetics

Reversible induction of mitophagy by an optogenetic bimodular system

D'Acunzo, P., Strappazzon, F., Caruana, I., Meneghetti, G., Di Rita, A., Simula, L., Weber, G., Del Bufalo, F., Dalla Valle, L., Campello, S., Locatelli, F. & Cecconi, F., Apr 4 2019, In : Nature Communications. 10, 1, p. 1533

Research output: Contribution to journalArticle

Mitochondrial Degradation
Optogenetics
Mitochondria
mitochondria
induction

Risk factors and outcomes according to age at transplantation with an HLA-identical sibling for sickle cell disease

Cappelli, B., Volt, F., Tozatto-Maio, K., Scigliuolo, G. M., Ferster, A., Dupont, S., Pinto Simões, B., Al-Seraihy, A., Aljurf, M. D., Almohareb, F., Belendez, C., Matthes, S., Dhedin, N., Pondarre, C., Dalle, J-H., Bertrand, Y., Vannier, J. P., Kuentz, M., Lutz, P., Michel, G. & 14 others, Rafii, H., Neven, B., Zecca, M., Bader, P., Cavazzana, M., Labopin, M., Locatelli, F., Magnani, A., Ruggeri, A., Rocha, V., Bernaudin, F., de La Fuente, J., Corbacioglu, S. & Gluckman, E., Apr 24 2019, In : Haematologica.

Research output: Contribution to journalArticle

Role of IFNγ in immune-mediated graft failure occurring after allogeneic hematopoietic stem cell transplantation

Merli, P., Caruana, I., De Vito, R., Strocchio, L., Weber, G., Del Bufalo, F., Buatois, V., Montanari, P., Cefalo, M. G., Pitisci, A., Algeri, M., Galaverna, F., Quintarelli, C., Cirillo, V., Pagliara, D., Ferlin, W., Ballabio, M., De Min, C. & Locatelli, F., Feb 21 2019, In : Haematologica.

Research output: Contribution to journalArticle

Hematopoietic Stem Cell Transplantation
Transplants
Tissue Donors
Hemophagocytic Lymphohistiocytosis
Chemokine CXCL9
Hepatic Veno-Occlusive Disease
Hematopoietic Stem Cell Transplantation
Stem Cell Transplantation
Hematology
Retrospective Studies

Targeted NGS Platforms for Genetic Screening and Gene Discovery in Primary Immunodeficiencies

Cifaldi, C., Brigida, I., Barzaghi, F., Zoccolillo, M., Ferradini, V., Petricone, D., Cicalese, M. P., Lazarevic, D., Cittaro, D., Omrani, M., Attardi, E., Conti, F., Scarselli, A., Chiriaco, M., Di Cesare, S., Licciardi, F., Davide, M., Ferrua, F., Canessa, C., Pignata, C. & 20 others, Giliani, S., Ferrari, S., Fousteri, G., Barera, G., Merli, P., Palma, P., Cesaro, S., Gattorno, M., Trizzino, A., Moschese, V., Chini, L., Villa, A., Azzari, C., Finocchi, A., Locatelli, F., Rossi, P., Sangiuolo, F., Aiuti, A., Cancrini, C. & Di Matteo, G., 2019, In : Frontiers in Immunology. 10, p. 316

Research output: Contribution to journalArticle

Genetic Testing
Genetic Association Studies
Ions
Phenotype
Genes
Neuromyelitis Optica
Hematopoietic Stem Cell Transplantation
T-Lymphocytes
Pediatrics
Immune System Diseases
Down Syndrome
Neoplasms
Therapeutics
Mutation
Neuroimaging
2018

ActivinA: a new leukemia-promoting factor conferring migratory advantage to B-cell precursor-acute lymphoblastic leukemic cells

Portale, F., Cricrì, G., Bresolin, S., Lupi, M., Gaspari, S., Silvestri, D., Russo, B., Marino, N., Ubezio, P., Pagni, F., Vergani, P., Te Kronnie, G., Valsecchi, M. G., Locatelli, F., Rizzari, C., Biondi, A., Dander, E. & D'Amico, G., Sep 27 2018, In : Haematologica.

Research output: Contribution to journalArticle

B-Lymphoid Precursor Cells
Leukemia
Bone Marrow
Aptitude
Mesenchymal Stromal Cells

Adoptive immunotherapy using prame-specific t cells in medulloblastoma

Orlando, D., Miele, E., De Angelis, B., Guercio, M., Boffa, I., Sinibaldi, M., Po, A., Caruana, I., Abballe, L., Carai, A., Caruso, S., Camera, A., Moseley, A., Hagedoorn, R. S., Heemskerk, M. H. M., Giangaspero, F., Mastronuzzi, A., Ferretti, E., Locatelli, F. & Quintarelli, C., Jun 15 2018, In : Cancer Research. 78, 12, p. 3337-3349 13 p.

Research output: Contribution to journalArticle

Adoptive Immunotherapy
Medulloblastoma
T-Lymphocytes
HLA-A Antigens
Caspase 9

Adoptive Immunotherapy Using PRAME-Specific T Cells in Medulloblastoma

Orlando, D., Miele, E., De Angelis, B., Guercio, M., Boffa, I., Sinibaldi, M., Po, A., Caruana, I., Abballe, L., Carai, A., Caruso, S., Camera, A., Moseley, A., Hagedoorn, R. S., Heemskerk, M. H. M., Giangaspero, F., Mastronuzzi, A., Ferretti, E., Locatelli, F. & Quintarelli, C., Jun 15 2018, In : Cancer Research. 78, 12, p. 3337-3349 13 p.

Research output: Contribution to journalArticle

Adoptive Immunotherapy
Medulloblastoma
T-Lymphocytes
HLA-A Antigens
Caspase 9

AMBRA1 Controls Regulatory T-Cell Differentiation and Homeostasis Upstream of the FOXO3-FOXP3 Axis

Becher, J., Simula, L., Volpe, E., Procaccini, C., La Rocca, C., D'Acunzo, P., Cianfanelli, V., Strappazzon, F., Caruana, I., Nazio, F., Weber, G., Gigantino, V., Botti, G., Ciccosanti, F., Borsellino, G., Campello, S., Mandolesi, G., De Bardi, M., Fimia, G. M., D'Amelio, M. & 11 others, Ruffini, F., Furlan, R., Centonze, D., Martino, G., Braghetta, P., Chrisam, M., Bonaldo, P., Matarese, G., Locatelli, F., Battistini, L. & Cecconi, F., Dec 3 2018, In : Developmental Cell. 47, 5, p. 592-607 15 p.

Research output: Contribution to journalArticle

T-cells
Regulatory T-Lymphocytes
Cell Differentiation
Homeostasis
Complex networks

AMBRA1 Controls Regulatory T-Cell Differentiation and Homeostasis Upstream of the FOXO3-FOXP3 Axis

Becher, J., Simula, L., Volpe, E., Procaccini, C., La Rocca, C., D'Acunzo, P., Cianfanelli, V., Strappazzon, F., Caruana, I., Nazio, F., Weber, G., Gigantino, V., Botti, G., Ciccosanti, F., Borsellino, G., Campello, S., Mandolesi, G., De Bardi, M., Fimia, G. M., D'Amelio, M. & 11 others, Ruffini, F., Furlan, R., Centonze, D., Martino, G., Braghetta, P., Chrisam, M., Bonaldo, P., Matarese, G., Locatelli, F., Battistini, L. & Cecconi, F., Dec 3 2018, In : Developmental Cell. p. 592-607 16 p.

Research output: Contribution to journalArticle

T-cells
Regulatory T-Lymphocytes
Cell Differentiation
Homeostasis
Disease Susceptibility

Analysis of KIR3DP1 polymorphism provides relevant information on centromeric KIR gene content

Bono, M., Pende, D., Bertaina, A., Moretta, A., Chiesa, M. D., Sivori, S., Zecca, M., Locatelli, F., Moretta, L., Bottino, C. & Falco, M., Sep 1 2018, In : Journal of Immunology. 201, 5, p. 1460-1467 8 p.

Research output: Contribution to journalArticle

Haplotypes
Genes
Alleles
Gene Dosage
Genetic Recombination

Analysis of KIR3DP1 Polymorphism Provides Relevant Information on Centromeric KIR Gene Content

Bono, M., Pende, D., Bertaina, A., Moretta, A., Della Chiesa, M., Sivori, S., Zecca, M., Locatelli, F., Moretta, L., Bottino, C. & Falco, M., Sep 1 2018, In : Journal of Immunology. 201, 5, p. 1460-1467 8 p.

Research output: Contribution to journalArticle

Haplotypes
Genes
Alleles
Gene Dosage
Genetic Recombination

A new baby in the c-Myc-directed transcriptional machinery: Che-1/AATF

Folgiero, V., Sorino, C., Locatelli, F. & Fanciulli, M., 2018, In : Cell Cycle. 17, 11, p. 1286-1290 5 p.

Research output: Contribution to journalArticle

B-Lymphoid Precursor Cells
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Karyotype
Cell Proliferation
Pediatrics

Arsenic trioxide and all-trans retinoic acid treatment for childhood acute promyelocytic leukaemia

Strocchio, L., Gurnari, C., Santoro, N., Putti, M. C., Micalizzi, C., Zecca, M., Cuccurullo, R., Girardi, K., Diverio, D., Testi, A. M., Lo-Coco, F. & Locatelli, F., Jan 1 2018, (Accepted/In press) In : British Journal of Haematology.

Research output: Contribution to journalArticle

Arsenic trioxide and all-trans retinoic acid treatment for childhood acute promyelocytic leukaemia

Strocchio, L., Gurnari, C., Santoro, N., Putti, M. C., Micalizzi, C., Zecca, M., Cuccurullo, R., Girardi, K., Diverio, D., Testi, A. M., Lo-Coco, F. & Locatelli, F., Jul 20 2018, In : British Journal of Haematology. 3 p.

Research output: Contribution to journalArticle

Stem Cell Transplantation
Hematopoietic Stem Cell Transplantation
Registries
Leukemia
T-Lymphocytes

Bone marrow failure may be caused by chromosome anomalies exerting effects on RUNX1T1 gene

Valli, R., Vinti, L., Frattini, A., Fabbri, M., Montalbano, G., Olivieri, C., Minelli, A., Locatelli, F., Pasquali, F. & Maserati, E., 2018, In : Molecular Cytogenetics. 11, 1

Research output: Contribution to journalArticle

Chromosomes
Bone
Aplastic Anemia
Genes
Bone Marrow