20112018

Research output per year

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2018

A rationally designed NRP1-independent superagonist SEMA3A mutant is an effective anticancer agent

Gioelli, N., Maione, F., Camillo, C., Ghitti, M., Valdembri, D., Morello, N., Darche, M., Zentilin, L., Cagnoni, G., Qiu, Y., Giacca, M., Giustetto, M., Paques, M., Cascone, I., Musco, G., Tamagnone, L., Giraudo, E. & Serini, G., May 23 2018, In : Science Translational Medicine. 10, 442, eaah4807.

Research output: Contribution to journalArticle

Downregulating neuropilin-2 triggers a novel mechanism enabling EGFR-dependent resistance to oncogene-targeted therapies

Rizzolio, S., Battistini, C., Cagnoni, G., Apicella, M., Vella, V., Giordano, S. & Tamagnone, L., Feb 15 2018, In : Cancer Research. 78, 4, p. 1058-1068 11 p.

Research output: Contribution to journalArticle

Neuropilin-1 upregulation elicits adaptive resistance to oncogene-targeted therapies

Rizzolio, S., Cagnoni, G., Battistini, C., Bonelli, S., Isella, C., Van Ginderachter, J. A., Bernards, R., Di Nicolantonio, F., Giordano, S. & Tamagnone, L., Aug 31 2018, In : Journal of Clinical Investigation. 128, 9, p. 3976-3990 15 p.

Research output: Contribution to journalArticle

2017

Downregulating Neuropilin-2 triggers a novel mechanism enabling EGFR-dependent resistance to oncogene-targeted therapies.

Rizzolio, S., Battistini, C., Cagnoni, G., Apicella, M., Vella, V., Giordano, S. & Tamagnone, L., Dec 1 2017, In : Cancer Research.

Research output: Contribution to journalArticle

2016

PlexinD1 is a novel transcriptional target and effector of notch signaling in cancer cells

Rehman, M., Gurrapu, S., Cagnoni, G., Capparuccia, L. & Tamagnone, L., Oct 1 2016, In : PLoS One. 11, 10, e0164660.

Research output: Contribution to journalArticle

2015

Semaphorin7A regulates neuroglial plasticity in the adult hypothalamic median eminence

Parkash, J., Messina, A., Langlet, F., Cimino, I., Loyens, A., Mazur, D., Gallet, S., Balland, E., Malone, S. A., Pralong, F., Cagnoni, G., Schellino, R., De Marchis, S., Mazzone, M., Pasterkamp, R. J., Tamagnone, L., Prevot, V. & Giacobini, P., Feb 27 2015, In : Nature Communications. 6, 6385.

Research output: Contribution to journalArticle

2014

Brain Endothelial Cells Control Fertility through Ovarian-Steroid-Dependent Release of Semaphorin 3A

Giacobini, P., Parkash, J., Campagne, C., Messina, A., Casoni, F., Vanacker, C., Langlet, F., Hobo, B., Cagnoni, G., Gallet, S., Hanchate, N. K., Mazur, D., Taniguchi, M., Mazzone, M., Verhaagen, J., Ciofi, P., Bouret, S. G., Tamagnone, L. & Prevot, V., 2014, In : PLoS Biology. 12, 3, e1001808.

Research output: Contribution to journalArticle

Semaphorin receptors meet receptor tyrosine kinases on the way of tumor progression

Cagnoni, G. & Tamagnone, L., Oct 2 2014, In : Oncogene. 33, 40, p. 4795-4802 8 p.

Research output: Contribution to journalArticle

2011

Dysregulation of semaphorin7A/β1-integrin signaling leads to defective GnRH-1 cell migration, abnormal gonadal development and altered fertility

Messina, A., Ferraris, N., Wray, S., Cagnoni, G., Donohue, D. E., Casoni, F., Kramer, P. R., Derijck, A. A., Adolfs, Y., Fasolo, A., Pasterkamp, R. J. & Giacobini, P., Dec 2011, In : Human Molecular Genetics. 20, 24, p. 4759-4774 16 p., ddr403.

Research output: Contribution to journalArticle