• 9405 Citations
  • 47 h-Index
1983 …2019
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Research Output 1983 2019

2019

Altered function of the glutamate–aspartate transporter GLAST, a potential therapeutic target in glioblastoma

Corbetta, C., Di Ianni, N., Bruzzone, M. G., Patanè, M., Pollo, B., Cantini, G., Cominelli, M., Zucca, I., Pisati, F., Poliani, P. L., Finocchiaro, G. & Pellegatta, S., Jan 1 2019, (Accepted/In press) In : International Journal of Cancer.

Research output: Contribution to journalArticle

Glioblastoma
Glutamic Acid
Glioma
Therapeutics
Apoptosis
2018

A Randomized Phase II Trial (TAMIGA) Evaluating the Efficacy and Safety of Continuous Bevacizumab Through Multiple Lines of Treatment for Recurrent Glioblastoma

Brandes, A. A., Gil-Gil, M., Saran, F., Carpentier, A. F., Nowak, A. K., Mason, W., Zagonel, V., Dubois, F., Finocchiaro, G., Fountzilas, G., Cernea, D. M., Chinot, O., Anghel, R., Ghiringhelli, F., Beauchesne, P., Lombardi, G., Franceschi, E., Makrutzki, M., Mpofu, C., Urban, H-J. & 1 others, Pichler, J., Sep 28 2018, In : The oncologist.

Research output: Contribution to journalArticle

Glioblastoma
Lomustine
Safety
temozolomide
Placebos
16 Citations (Scopus)

Constitutive and TNFα-inducible expression of chondroitin sulfate proteoglycan 4 in glioblastoma and neurospheres: Implications for CAR-T cell therapy

Pellegatta, S., Savoldo, B., Di Ianni, N., Corbetta, C., Chen, Y., Patané, M., Sun, C., Pollo, B., Ferrone, S., DiMeco, F., Finocchiaro, G. & Dotti, G., Feb 28 2018, In : Science Translational Medicine. 10, 430, eaao2731.

Research output: Contribution to journalArticle

Antigen Receptors
Glioblastoma
Cell- and Tissue-Based Therapy
Tumor Necrosis Factor-alpha
Neoplasms
9 Citations (Scopus)
temozolomide
Glioblastoma
Immunotherapy
Dendritic Cells
T-Lymphocytes

The molecular landscape of glioma in patients with Neurofibromatosis 1

D'Angelo, F., Ceccarelli, M., Tala, J., Garofano, L., Zhang, J., Frattini, V., Caruso, F. P., Lewis, G., Alfaro, K. D., Bauchet, L., Berzero, G., Cachia, D., Cangiano, M., Capelle, L., de Groot, J., DiMeco, F., Ducray, F., Farah, W., Finocchiaro, G., Goutagny, S. & 27 others, Kamiya-Matsuoka, C., Lavarino, C., Loiseau, H., Lorgis, V., Marras, C. E., McCutcheon, I., Nam, D-H., Ronchi, S., Saletti, V., Seizeur, R., Slopis, J., Suñol, M., Vandenbos, F., Varlet, P., Vidaud, D., Watts, C., Tabar, V., Reuss, D. E., Kim, S-K., Meyronet, D., Mokhtari, K., Salvador, H., Bhat, K. P., Eoli, M., Sanson, M., Lasorella, A. & Iavarone, A., Dec 10 2018, In : Nature Medicine.

Research output: Contribution to journalArticle

Neurofibromatosis 1
Glioma
Tumors
Genes
Isocitrate Dehydrogenase
2017
2 Citations (Scopus)

Diffuse glioblastoma resembling acute hemorrhagic leukoencephalitis

Schettino, C., Caranci, F., Lus, G., Signoriello, E., Eoli, M., Anghileri, E., Pollo, B., Melone, M. A. B., Di Iorio, G., Finocchiaro, G., Ugga, L. & Tedeschi, E., Oct 1 2017, In : Quantitative Imaging in Medicine and Surgery. 7, 5, p. 592-597 6 p.

Research output: Contribution to journalArticle

Acute Hemorrhagic Leukoencephalitis
Glioblastoma
Glioma
Gait Ataxia
Acute Disseminated Encephalomyelitis
3 Citations (Scopus)

Fibronectin-adherent peripheral blood derived mononuclear cells as Paclitaxel carriers for glioblastoma treatment: An in vitro study

Schiariti, M. P., Restelli, F., Ferroli, P., Benetti, A., Berenzi, A., Ferri, A., Ceserani, V., Ciusani, E., Cadei, M., Finocchiaro, G., Pessina, A., Parati, E., Pallini, R. & Alessandri, G., Jun 1 2017, In : Cytotherapy. 19, 6, p. 721-734 14 p.

Research output: Contribution to journalArticle

Glioblastoma
Paclitaxel
Fibronectins
Therapeutics
In Vitro Techniques
12 Citations (Scopus)

Genetic Evolution of Glioblastoma Stem-Like Cells From Primary to Recurrent Tumor

Orzan, F., De Bacco, F., Crisafulli, G., Pellegatta, S., Mussolin, B., Siravegna, G., D'Ambrosio, A., Comoglio, P. M., Finocchiaro, G. & Boccaccio, C., Nov 1 2017, In : Stem Cells. 35, 11, p. 2218-2228 11 p.

Research output: Contribution to journalArticle

Molecular Evolution
Glioblastoma
Stem Cells
Neoplasms
temozolomide
3 Citations (Scopus)

Go, no-go decision making for phase 3 clinical trials: ACT IV revisited – Authors' reply

Weller, M., Butowski, N., Tran, D. D., Recht, L. D., Lim, M., Hirte, H., Ashby, L., Mechtler, L., Goldlust, S. A., Iwamoto, F., Drappatz, J., O'Rourke, D. M., Wong, M., Hamilton, M. G., Finocchiaro, G., Perry, J., Wick, W., Green, J., He, Y., Turner, C. D. & 5 others, Yellin, M. J., Keler, T., Davis, T. A., Stupp, R. & Sampson, J. H., Dec 1 2017, In : The Lancet Oncology. 18, 12, p. e709-e710

Research output: Contribution to journalLetter

8 Citations (Scopus)

Hypermutations in gliomas: A potential immunotherapy target

Finocchiaro, G., Langella, T., Corbetta, C. & Pellegatta, S., Jan 1 2017, In : Discovery medicine. 23, 125, p. 113-120 8 p.

Research output: Contribution to journalArticle

Glioma
Immunotherapy
temozolomide
DNA Mismatch Repair
Neoplasms
151 Citations (Scopus)

Intertumoral Heterogeneity within Medulloblastoma Subgroups

Cavalli, F. M. G., Remke, M., Rampasek, L., Peacock, J., Shih, D. J. H., Luu, B., Garzia, L., Torchia, J., Nor, C., Morrissy, A. S., Agnihotri, S., Thompson, Y. Y., Kuzan-Fischer, C. M., Farooq, H., Isaev, K., Daniels, C., Cho, B-K., Kim, S-K., Wang, K-C., Lee, J. Y. & 75 others, Grajkowska, W. A., Perek-Polnik, M., Vasiljevic, A., Faure-Conter, C., Jouvet, A., Giannini, C., Nageswara Rao, A. A., Li, K. K. W., Ng, H-K., Eberhart, C. G., Pollack, I. F., Hamilton, R. L., Gillespie, G. Y., Olson, J. M., Leary, S., Weiss, W. A., Lach, B., Chambless, L. B., Thompson, R. C., Cooper, M. K., Vibhakar, R., Hauser, P., van Veelen, M-LC., Kros, J. M., French, P. J., Ra, Y. S., Kumabe, T., López-Aguilar, E., Zitterbart, K., Sterba, J., Finocchiaro, G., Massimino, M., Van Meir, E. G., Osuka, S., Shofuda, T., Klekner, A., Zollo, M., Leonard, J. R., Rubin, J. B., Jabado, N., Albrecht, S., Mora, J., Van Meter, T. E., Jung, S., Moore, A. S., Hallahan, A. R., Chan, J. A., Tirapelli, D. P. C., Carlotti, C. G., Fouladi, M., Pimentel, J., Faria, C. C., Saad, A. G., Massimi, L., Liau, L. M., Wheeler, H., Nakamura, H., Elbabaa, S. K., Perezpeña-Diazconti, M., Chico Ponce de León, F., Robinson, S., Zapotocky, M., Lassaletta, A., Huang, A., Hawkins, C. E., Tabori, U., Bouffet, E., Bartels, U., Dirks, P. B., Rutka, J. T., Bader, G. D., Reimand, J., Goldenberg, A., Ramaswamy, V. & Taylor, M. D., 2017, In : Cancer Cell. 31, 6, p. 737-754.e6

Research output: Contribution to journalArticle

151 Citations (Scopus)

Intertumoral Heterogeneity within Medulloblastoma Subgroups

Cavalli, F. M. G., Remke, M., Rampasek, L., Peacock, J., Shih, D. J. H., Luu, B., Garzia, L., Torchia, J., Nor, C., Morrissy, A. S., Agnihotri, S., Thompson, Y. Y., Kuzan-Fischer, C. M., Farooq, H., Isaev, K., Daniels, C., Cho, B. K., Kim, S. K., Wang, K. C., Lee, J. Y. & 75 others, Grajkowska, W. A., Perek-Polnik, M., Vasiljevic, A., Faure-Conter, C., Jouvet, A., Giannini, C., Nageswara Rao, A. A., Li, K. K. W., Ng, H. K., Eberhart, C. G., Pollack, I. F., Hamilton, R. L., Gillespie, G. Y., Olson, J. M., Leary, S., Weiss, W. A., Lach, B., Chambless, L. B., Thompson, R. C., Cooper, M. K., Vibhakar, R., Hauser, P., van Veelen, M. L. C., Kros, J. M., French, P. J., Ra, Y. S., Kumabe, T., López-Aguilar, E., Zitterbart, K., Sterba, J., Finocchiaro, G., Massimino, M., Van Meir, E. G., Osuka, S., Shofuda, T., Klekner, A., Zollo, M., Leonard, J. R., Rubin, J. B., Jabado, N., Albrecht, S., Mora, J., Van Meter, T. E., Jung, S., Moore, A. S., Hallahan, A. R., Chan, J. A., Tirapelli, D. P. C., Carlotti, C. G., Fouladi, M., Pimentel, J., Faria, C. C., Saad, A. G., Massimi, L., Liau, L. M., Wheeler, H., Nakamura, H., Elbabaa, S. K., Perezpeña-Diazconti, M., Chico Ponce de León, F., Robinson, S., Zapotocky, M., Lassaletta, A., Huang, A., Hawkins, C. E., Tabori, U., Bouffet, E., Bartels, U., Dirks, P. B., Rutka, J. T., Bader, G. D., Reimand, J., Goldenberg, A., Ramaswamy, V. & Taylor, M. D., Jun 12 2017, In : Cancer Cell. 31, 6, p. 737-754.e6

Research output: Contribution to journalArticle

Medulloblastoma
DNA Methylation
Cluster Analysis
Clinical Trials
Genome
15 Citations (Scopus)

MRI in Glioma Immunotherapy: Evidence, Pitfalls, and Perspectives

Aquino, D., Gioppo, A., Finocchiaro, G., Bruzzone, M. G. & Cuccarini, V., Jan 1 2017, In : Journal of Immunology Research. 2017, 5813951.

Research output: Contribution to journalReview article

Glioma
Immunotherapy
Glioblastoma
Dendritic Cells
Immune System
19 Citations (Scopus)

Randomized, double-blind, placebo-controlled, multicenter phase II study of onartuzumab plus bevacizumab versus placebo plus bevacizumab in patients with recurrent glioblastoma: Efficacy, safety, and hepatocyte growth factor and O6-methylguanine-DNA methyltransferase biomarker analyses

Cloughesy, T., Finocchiaro, G., Belda-Iniesta, C., Recht, L., Brandes, A. A., Pineda, E., Mikkelsen, T., Chinot, O. L., Balana, C., Macdonald, D. R., Westphal, M., Hopkins, K., Weller, M., Bais, C., Sandmann, T., Bruey, J. M., Koeppen, H., Liu, B., Verret, W., Phan, S. C. & 1 others, Shames, D. S., Jan 20 2017, In : Journal of Clinical Oncology. 35, 3, p. 343-351 9 p.

Research output: Contribution to journalArticle

Hepatocyte Growth Factor
Methyltransferases
Glioblastoma
Biomarkers
Placebos
145 Citations (Scopus)

Rindopepimut with temozolomide for patients with newly diagnosed, EGFRvIII-expressing glioblastoma (ACT IV): a randomised, double-blind, international phase 3 trial

Weller, M., Butowski, N., Tran, D. D., Recht, L., Lim, M., Hirte, H., Ashby, L., Mechtler, L., Goldlust, S. A., Iwamoto, F., Drappatz, J., O'Rourke, D. M., Wong, M., Hamilton, M. G., Finocchiaro, G., Perry, J., Wick, W., Green, J., He, Y., Turner, C. D. & 32 others, Yellin, M. J., Keler, T., Davis, T. A., Stupp, R., Sampson, J. H., Butowski, N., Campian, J., Recht, L., Lim, M., Ashby, L., Drappatz, J., Hirte, H., Iwamoto, F., Mechtler, L., Goldlust, S., Becker, K., Barnett, G., Nicholas, G., Desjardins, A., Benkers, T., Wagle, N., Groves, M., Kesari, S., Horvath, Z., Merrell, R., Curry, R., O'Rourke, J., Schuster, D., Wong, M., Finocchiaro, G., ACT IV trial investigators & ACT IV trial investigators, Oct 1 2017, In : The Lancet Oncology. 18, 10, p. 1373-1385 13 p.

Research output: Contribution to journalArticle

temozolomide
Glioblastoma
Survival
Brain Edema
Control Groups
4 Citations (Scopus)

TLRgeting Evasion of Immune Pathways in Glioblastoma

Finocchiaro, G., Apr 6 2017, In : Cell Stem Cell. 20, 4, p. 422-424 3 p.

Research output: Contribution to journalShort survey

Immune Evasion
Neoplastic Stem Cells
Glioblastoma
Toll-Like Receptor 4
Toll-Like Receptors
137 Citations (Scopus)

Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment

Wang, Q., Hu, B., Hu, X., Kim, H., Squatrito, M., Scarpace, L., deCarvalho, A. C., Lyu, S., Li, P., Li, Y., Barthel, F., Cho, H. J., Lin, Y. H., Satani, N., Martinez-Ledesma, E., Zheng, S., Chang, E., Sauvé, C. E. G., Olar, A., Lan, Z. D. & 14 others, Finocchiaro, G., Phillips, J. J., Berger, M. S., Gabrusiewicz, K. R., Wang, G., Eskilsson, E., Hu, J., Mikkelsen, T., DePinho, R. A., Muller, F., Heimberger, A. B., Sulman, E. P., Nam, D. H. & Verhaak, R. G. W., Jul 10 2017, In : Cancer Cell. 32, 1, p. 42-56.e6

Research output: Contribution to journalArticle

Glioma
Microglia
Macrophages
Gene Expression
Tumor Microenvironment
2016
15 Citations (Scopus)

Advanced MRI may complement histological diagnosis of lower grade gliomas and help in predicting survival

Cuccarini, V., Erbetta, A., Farinotti, M., Cuppini, L., Ghielmetti, F., Pollo, B., Di Meco, F., Grisoli, M., Filippini, G., Finocchiaro, G., Bruzzone, M. G. & Eoli, M., 2016, In : Journal of Neuro-Oncology. 126, 2, p. 279-288 10 p.

Research output: Contribution to journalComment/debate

Glioma
Survival
Perfusion Imaging
ROC Curve
Edema
25 Citations (Scopus)

A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways

Huang, T., Alvarez, A. A., Pangeni, R. P., Horbinski, C. M., Lu, S., Kim, S. H., James, C. D., Raizer, J. J., Kessler, J. A., Brenann, C. W., Sulman, E. P., Finocchiaro, G., Tan, M., Nishikawa, R., Lu, X., Nakano, I., Hu, B. & Cheng, S. Y., Oct 4 2016, In : Nature Communications. 7, 12885.

Research output: Contribution to journalArticle

phenotype
Glioblastoma
regulators
Phenotype
Networks (circuits)

AVAREG: A phase II, randomized, noncomparative study of fotemustine or bevacizumab for patients with recurrent glioblastoma

Brandes, A., Finocchiaro, G., Zagonel, V., Reni, M., Caserta, C., Fabi, A., Clavarezza, M., Maiello, E., Eoli, M., Lombardi, G., Monteforte, M., Proietti, E., Agati, R., Eusebi, V. & Franceschi, E., Sep 1 2016, In : Neuro-Oncology. 18, 9, p. 1304-1312 9 p.

Research output: Contribution to journalArticle

fotemustine
Glioblastoma
Confidence Intervals
Survival Rate
Survival
18 Citations (Scopus)

AVAREG: A phase II, randomized, noncomparative study of fotemustine or bevacizumab for patients with recurrent glioblastoma

Brandes, A. A., Finocchiaro, G., Zagonel, V., Reni, M., Caserta, C., Fabi, A., Clavarezza, M., Maiello, E., Eoli, M., Lombardi, G., Monteforte, M., Proietti, E., Agati, R., Eusebi, V. & Franceschi, E., Sep 1 2016, In : Neuro-Oncology. 18, 9, p. 1304-1312 9 p.

Research output: Contribution to journalArticle

fotemustine
Glioblastoma
Confidence Intervals
Survival Rate
Survival

AVAREG: A phase II, randomized, noncomparative study of fotemustine or bevacizumab for patients with recurrent glioblastoma

Brandes, A., Finocchiaro, G., Zagonel, V., Reni, M., Caserta, C., Fabi, A., Clavarezza, M., Maiello, E., Eoli, M., Lombardi, G., Monteforte, M., Proietti, E., Agati, R., Eusebi, V. & Franceschi, E., Sep 1 2016, In : Neuro-Oncology. 18, 9, p. 1304-1312 9 p.

Research output: Contribution to journalArticle

fotemustine
Glioblastoma
Confidence Intervals
Survival Rate
Survival

AVAREG: A phase II, randomized, noncomparative study of fotemustine or bevacizumab for patients with recurrent glioblastoma

Brandes, A., Finocchiaro, G., Zagonel, V., Reni, M., Caserta, C., Fabi, A., Clavarezza, M., Maiello, E., Eoli, M., Lombardi, G., Monteforte, M., Proietti, E., Agati, R., Eusebi, V. & Franceschi, E., Sep 1 2016, In : Neuro-Oncology. 18, 9, p. 1304-1312 9 p.

Research output: Contribution to journalArticle

fotemustine
Glioblastoma
Confidence Intervals
Survival Rate
Survival
157 Citations (Scopus)

Clonal evolution of glioblastoma under therapy

Wang, J., Cazzato, E., Ladewig, E., Frattini, V., Rosenbloom, D. I. S., Zairis, S., Abate, F., Liu, Z., Elliott, O., Shin, Y. J., Lee, J. K., Lee, I. H., Park, W. Y., Eoli, M., Blumberg, A. J., Lasorella, A., Nam, D. H., Finocchiaro, G., Iavarone, A. & Rabadan, R., Jul 1 2016, In : Nature Genetics. 48, 7, p. 768-776 9 p.

Research output: Contribution to journalArticle

Clonal Evolution
Glioblastoma
Recurrence
Therapeutics
Protein Binding
68 Citations (Scopus)

Epigenetic Activation of WNT5A Drives Glioblastoma Stem Cell Differentiation and Invasive Growth

Hu, B., Wang, Q., Wang, Y. A., Hua, S., Sauvé, C. E. G., Ong, D., Lan, Z. D., Chang, Q., Ho, Y. W., Monasterio, M. M., Lu, X., Zhong, Y., Zhang, J., Deng, P., Tan, Z., Wang, G., Liao, W. T., Corley, L. J., Yan, H., Zhang, J. & 13 others, You, Y., Liu, N., Cai, L., Finocchiaro, G., Phillips, J. J., Berger, M. S., Spring, D. J., Hu, J., Sulman, E. P., Fuller, G. N., Chin, L., Verhaak, R. G. W. & DePinho, R. A., Nov 17 2016, In : Cell. 167, 5, p. 1281-1295.e18

Research output: Contribution to journalArticle

Glioblastoma
Stem cells
Epigenomics
Cell Differentiation
Stem Cells
13 Citations (Scopus)

Extraneural metastases in glioblastoma patients: two cases with YKL-40-positive glioblastomas and a meta-analysis of the literature

Elena, A., Melina, C., Raffaele, N., Carlo, B., Vittoria, N., Francesco, A., Gaetano, F. & Marica, E., Jan 1 2016, In : Neurosurgical Review. 39, 1, p. 37-46 10 p.

Research output: Contribution to journalArticle

Glioblastoma
Meta-Analysis
Neoplasm Metastasis
Survival
Recurrence
7 Citations (Scopus)

Human glioblastoma stem-like cells accumulate protoporphyrin IX when subjected to exogenous 5-aminolaevulinic acid, rendering them sensitive to photodynamic treatment

Schimanski, A., Ebbert, L., Sabel, M. C., Finocchiaro, G., Lamszus, K., Ewelt, C., Etminan, N., Fischer, J. C. & Sorg, R. V., Oct 1 2016, In : Journal of Photochemistry and Photobiology B: Biology. 163, p. 203-210 8 p.

Research output: Contribution to journalArticle

Aminolevulinic Acid
stem cells
Glioblastoma
Stem Cells
acids
20 Citations (Scopus)
Glioblastoma
Immunotherapy
Dendritic Cells
Stem Cells
Cancer Vaccines
29 Citations (Scopus)

MET inhibition overcomes radiation resistance of glioblastoma stem-like cells

De Bacco, F., D'Ambrosio, A., Casanova, E., Orzan, F., Neggia, R., Albano, R., Verginelli, F., Cominelli, M., Poliani, P. L., Luraghi, P., Reato, G., Pellegatta, S., Finocchiaro, G., Perera, T., Garibaldi, E., Gabriele, P., Comoglio, P. M. & Boccaccio, C., May 1 2016, In : EMBO Molecular Medicine. 8, 5, p. 550-568 19 p.

Research output: Contribution to journalArticle

Glioblastoma
Stem Cells
Radiation
DNA Damage
Radiotherapy

MET inhibition overcomes radiation resistance of glioblastoma stem-like cells

De Bacco, F., D'Ambrosio, A., Casanova, E., Orzan, F., Neggia, R., Albano, R., Verginelli, F., Cominelli, M., Poliani, P. L., Luraghi, P., Reato, G., Pellegatta, S., Finocchiaro, G., Perera, T., Garibaldi, E., Gabriele, P., Comoglio, P. M. & Boccaccio, C., May 1 2016, In : EMBO Molecular Medicine. 8, 5, p. 550-568 19 p.

Research output: Contribution to journalArticle

Glioblastoma
Stem Cells
Radiation
DNA Damage
Radiotherapy
3 Citations (Scopus)

Principles of immunotherapy

Liebelt, B. D., Finocchiaro, G. & Heimberger, A. B., 2016, Gliomas, 2016. Elsevier, Vol. 134. p. 163-181 19 p. (Handbook of Clinical Neurology; vol. 134).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Immunotherapy
Glioblastoma
Immune System
Therapeutics
Nervous System Neoplasms
7 Citations (Scopus)

The multidrug-resistance transporter Abcc3 protects NK cells from chemotherapy in a murine model of malignant glioma

Pessina, S., Cantini, G., Kapetis, D., Cazzato, E., Di Ianni, N., Finocchiaro, G. & Pellegatta, S., Apr 18 2016, (Accepted/In press) In : OncoImmunology.

Research output: Contribution to journalArticle

temozolomide
Multiple Drug Resistance
Glioma
Natural Killer Cells
Drug Therapy
4 Citations (Scopus)

Ultrasonic Surgical Aspirate is a Reliable Source for Culturing Glioblastoma Stem Cells

Behnan, J., Stangeland, B., Langella, T., Finocchiaro, G., Murrell, W. & Brinchmann, J. E., Sep 8 2016, In : Scientific Reports. 6, 32788.

Research output: Contribution to journalArticle

Glioblastoma
Ultrasonics
Glioma
Stem Cells
Biopsy
2015
Glioma
Survival
Perfusion Imaging
ROC Curve
Edema
907 Citations (Scopus)

Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas

Brat, D. J., Verhaak, R. G. W., Aldape, K. D., Yung, W. K. A., Salama, S. R., Cooper, L. A. D., Rheinbay, E., Miller, C. R., Vitucci, M., Morozova, O., Robertson, A. G., Noushmehr, H., Laird, P. W., Cherniack, A. D., Akbani, R., Huse, J. T., Ciriello, G., Poisson, L. M., Barnholtz-Sloan, J. S., Berger, M. S. & 287 others, Brennan, C., Colen, R. R., Colman, H., Flanders, A. E., Giannini, C., Grifford, M., Iavarone, A., Jain, R., Joseph, I., Kim, J., Kasaian, K., Mikkelsen, T., Murray, B. A., O'Neill, B. P., Pachter, L., Parsons, D. W., Sougnez, C., Sulman, E. P., Vandenberg, S. R., Van Meir, E. G., Von Deimling, A., Zhang, H., Crain, D., Lau, K., Mallery, D., Morris, S., Paulauskis, J., Penny, R., Shelton, T., Sherman, M., Yena, P., Black, A., Bowen, J., Dicostanzo, K., Gastier-Foster, J., Leraas, K. M., Lichtenberg, T. M., Pierson, C. R., Ramirez, N. C., Taylor, C., Weaver, S., Wise, L., Zmuda, E., Davidsen, T., Demchok, J. A., Eley, G., Ferguson, M. L., Hutter, C. M., Shaw, K. R. M., Ozenberger, B. A., Sheth, M., Sofia, H. J., Tarnuzzer, R., Wang, Z., Yang, L., Zenklusen, J. C., Ayala, B., Baboud, J., Chudamani, S., Jensen, M. A., Liu, J., Pihl, T., Raman, R., Wan, Y., Wu, Y., Ally, A., Auman, J. T., Balasundaram, M., Balu, S., Baylin, S. B., Beroukhim, R., Bootwalla, M. S., Bowlby, R., Bristow, C. A., Brooks, D., Butterfield, Y., Carlsen, R., Carter, S., Chin, L., Chu, A., Chuah, E., Cibulskis, K., Clarke, A., Coetzee, S. G., Dhalla, N., Fennell, T., Fisher, S., Gabriel, S., Getz, G., Gibbs, R., Guin, R., Hadjipanayis, A., Hayes, D. N., Hinoue, T., Hoadley, K., Holt, R. A., Hoyle, A. P., Jefferys, S. R., Jones, S., Jones, C. D., Kucherlapati, R., Lai, P. H., Lander, E., Lee, S., Lichtenstein, L., Ma, Y., Maglinte, D. T., Mahadeshwar, H. S., Marra, M. A., Mayo, M., Meng, S., Meyerson, M. L., Mieczkowski, P. A., Moore, R. A., Mose, L. E., Mungall, A. J., Pantazi, A., Parfenov, M., Park, P. J., Parker, J. S., Perou, C. M., Protopopov, A., Ren, X., Roach, J., Sabedot, T. S., Schein, J., Schumacher, S. E., Seidman, J. G., Seth, S., Shen, H., Simons, J. V., Sipahimalani, P., Soloway, M. G., Song, X., Sun, H., Tabak, B., Tam, A., Tan, D., Tang, J., Thiessen, N., Triche, T., Van Den Berg, D. J., Veluvolu, U., Waring, S., Weisenberger, D. J., Wilkerson, M. D., Wong, T., Wu, J., Xi, L., Xu, A. W., Yang, L., Zack, T. I., Zhang, J., Aksoy, B. A., Arachchi, H., Benz, C., Bernard, B., Carlin, D., Cho, J., DiCara, D., Frazer, S., Fuller, G. N., Gao, J., Gehlenborg, N., Haussler, D., Heiman, D. I., Iype, L., Jacobsen, A., Ju, Z., Katzman, S., Kim, H., Knijnenburg, T., Kreisberg, R. B., Lawrence, M. S., Lee, W., Leinonen, K., Lin, P., Ling, S., Liu, W., Liu, Y., Liu, Y., Lu, Y., Mills, G., Ng, S., Noble, M. S., Paull, E., Rao, A., Reynolds, S., Saksena, G., Sanborn, Z., Sander, C., Schultz, N., Senbabaoglu, Y., Shen, R., Shmulevich, I., Sinha, R., Stuart, J., Sumer, S. O., Sun, Y., Tasman, N., Taylor, B. S., Voet, D., Weinhold, N., Weinstein, J. N., Yang, D., Yoshihara, K., Zheng, S., Zhang, W., Zou, L., Abel, T., Sadeghi, S., Cohen, M. L., Eschbacher, J., Hattab, E. M., Raghunathan, A., Schniederjan, M. J., Aziz, D., Barnett, G., Barrett, W., Bigner, D. D., Boice, L., Brewer, C., Calatozzolo, C., Campos, B., Carlotti, C. G., Chan, T. A., Cuppini, L., Curley, E., Cuzzubbo, S., Devine, K., DiMeco, F., Duell, R., Elder, J. B., Fehrenbach, A., Finocchiaro, G., Friedman, W., Fulop, J., Gardner, J., Hermes, B., Herold-Mende, C., Jungk, C., Kendler, A., Lehman, N. L., Lipp, E., Liu, O., Mandt, R., McGraw, M., Mclendon, R., McPherson, C., Neder, L., Nguyen, P., Noss, A., Nunziata, R., Ostrom, Q. T., Palmer, C., Perin, A., Pollo, B., Potapov, A., Potapova, O., Rathmell, W. K., Rotin, D., Scarpace, L., Schilero, C., Senecal, K., Shimmel, K., Shurkhay, V., Sifri, S., Singh, R., Sloan, A. E., Smolenski, K., Staugaitis, S. M., Steele, R., Thorne, L., Tirapelli, D. P. C., Unterberg, A., Vallurupalli, M., Wang, Y., Warnick, R., Williams, F., Wolinsky, Y., Bell, S., Rosenberg, M., Stewart, C., Huang, F., Grimsby, J. L., Radenbaugh, A. J. & Zhang, J., Jun 25 2015, In : New England Journal of Medicine. 372, 26, p. 2481-2498 18 p.

Research output: Contribution to journalArticle

Glioma
Mutation
Glioblastoma
DNA Methylation
Exome
87 Citations (Scopus)

Detection, characterization, and inhibition of FGFR-TACC fusions in IDH wild-type glioma

Di Stefano, A. L., Fucci, A., Frattini, V., Labussiere, M., Mokhtari, K., Zoppoli, P., Marie, Y., Bruno, A., Boisselier, B., Giry, M., Savatovsky, J., Touat, M., Belaid, H., Kamoun, A., Idbaih, A., Houillier, C., Luo, F. R., Soria, J. C., Tabernero, J., Eoli, M. & 8 others, Paterra, R., Yip, S., Petrecca, K., Chan, J. A., Finocchiaro, G., Lasorella, A., Sanson, M. & Iavarone, A., Jul 15 2015, In : Clinical Cancer Research. 21, 14, p. 3307-3317 11 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor Receptors
Glioma
Glioblastoma
Mutation
Research Design
19 Citations (Scopus)

EGFR amplified and overexpressing glioblastomas and association with better response to adjuvant metronomic temozolomide

Cominelli, M., Grisanti, S., Mazzoleni, S., Branca, C., Buttolo, L., Furlan, D., Liserre, B., Bonetti, M. F., Medicina, D., Pellegrini, V., Buglione, M., Liserre, R., Pellegatta, S., Finocchiaro, G., Dalerba, P., Facchetti, F., Pizzi, M., Galli, R. & Poliani, P. L., May 1 2015, In : Journal of the National Cancer Institute. 107, 5, djv041.

Research output: Contribution to journalArticle

temozolomide
Glioblastoma
Survival
Neoplastic Stem Cells
Methylation
176 Citations (Scopus)

Immunotherapy response assessment in neuro-oncology: A report of the RANO working group

Okada, H., Weller, M., Huang, R., Finocchiaro, G., Gilbert, M. R., Wick, W., Ellingson, B. M., Hashimoto, N., Pollack, I. F., Brandes, A. A., Franceschi, E., Herold-Mende, C., Nayak, L., Panigrahy, A., Pope, W. B., Prins, R., Sampson, J. H., Wen, P. Y. & Reardon, D. A., 2015, In : The Lancet Oncology. 16, 15, p. e534-e542

Research output: Contribution to journalArticle

Immunotherapy
Neoplasms
Guidelines
Disease Progression
Adrenal Cortex Hormones
8 Citations (Scopus)

Novel mechanisms and approaches in immunotherapy for brain tumors

Finocchiaro, G. & Pellegatta, S., 2015, In : Discovery medicine. 20, 108, p. 7-15 9 p.

Research output: Contribution to journalArticle

Brain Neoplasms
Immunotherapy
Neoplasms
Glioma
Dendritic Cells
14 Citations (Scopus)

Radiosurgery reirradiation for high-grade glioma recurrence: a retrospective analysis

Pinzi, V., Orsi, C., Marchetti, M., Milanesi, I. M., Bianchi, L. C., DiMeco, F., Cuccarini, V., Farinotti, M., Ferroli, P., Finocchiaro, G., Franzini, A., Fumagalli, M. L., Silvani, A. & Fariselli, L., Aug 28 2015, In : Neurological Sciences. 36, 8, p. 1431-1440 10 p.

Research output: Contribution to journalArticle

Radiosurgery
Glioma
Recurrence
Survival
Survival Rate
10 Citations (Scopus)
Glioblastoma
Immunotherapy
Dendritic Cells
Clinical Trials, Phase I
Mixed Lymphocyte Culture Test
19 Citations (Scopus)

VEGFA SNP rs2010963 is associated with vascular toxicity in recurrent glioblastomas and longer response to bevacizumab

Di Stefano, A. L., Labussiere, M., Lombardi, G., Eoli, M., Bianchessi, D., Pasqualetti, F., Farina, P., Cuzzubbo, S., Gallego-Perez-Larraya, J., Boisselier, B., Ducray, F., Cheneau, C., Moglia, A., Finocchiaro, G., Marie, Y., Rahimian, A., Hoang-Xuan, K., Delattre, J. Y., Mokhtari, K. & Sanson, M., 2015, In : Journal of Neuro-Oncology. 121, 3, p. 499-504 6 p.

Research output: Contribution to journalArticle

Glioblastoma
Single Nucleotide Polymorphism
Blood Vessels
temozolomide
Genotype
2014
12 Citations (Scopus)

Accuracy of 2-hydroxyglutarate quantification by short-echo proton-MRS at 3 T: A phantom study

Bertolino, N., Marchionni, C., Ghielmetti, F., Burns, B., Finocchiaro, G., Anghileri, E., Bruzzone, M. G. & Minati, L., 2014, In : Physica Medica. 30, 6, p. 702-707 6 p.

Research output: Contribution to journalArticle

glutamates
Protons
echoes
Glutamic Acid
protons
12 Citations (Scopus)

A subpopulation of circulating endothelial cells express CD109 and is enriched in the blood of cancer patients

Mancuso, P., Calleri, A., Gregato, G., Labanca, V., Quarna, J., Antoniotti, P., Cuppini, L., Finocchiaro, G., Eoli, M., Rosti, V. & Bertolini, F., Dec 15 2014, In : PLoS One. 9, 12, e114713.

Research output: Contribution to journalArticle

Endothelial cells
endothelial cells
Blood
Endothelial Cells
neoplasms
85 Citations (Scopus)

Combined analysis of TERT, EGFR, and IDH status defines distinct prognostic glioblastoma classes

Labussière, M., Boisselier, B., Mokhtari, K., Di Stefano, A. L., Rahimian, A., Rossetto, M., Ciccarino, P., Saulnier, O., Paterra, R., Marie, Y., Finocchiaro, G. & Sanson, M., Sep 1 2014, In : Neurology. 83, 13, p. 1200-1206 7 p.

Research output: Contribution to journalArticle

Glioblastoma
Mutation
Survival
Chromosomes, Human, Pair 10
Methylation
8 Citations (Scopus)

Erratum: The somatic genomic landscape of glioblastoma (Cell (2013) 155 (462-477))

Brennan, C. W., Verhaak, R. G. W., McKenna, A., Campos, B., Noushmehr, H., Salama, S. R., Zheng, S., Chakravarty, D., Sanborn, J. Z., Berman, S. H., Beroukhim, R., Bernard, B., Wu, C. J., Genovese, G., Shmulevich, I., Barnholtz-Sloan, J., Zou, L., Vegesna, R., Shukla, S. A., Ciriello, G. & 38 others, Yung, W. K., Zhang, W., Sougnez, C., Mikkelsen, T., Aldape, K., Bigner, D. D., Van Meir, E. G., Prados, M., Sloan, A., Black, K. L., Eschbacher, J., Finocchiaro, G., Friedman, W., Andrews, D. W., Guha, A., Iacocca, M., O'Neill, B. P., Foltz, G., Myers, J., Weisenberger, D. J., Penny, R., Kucherlapati, R., Perou, C. M., Hayes, D. N., Gibbs, R., Marra, M., Mills, G. B., Lander, E., Spellman, P., Wilson, R., Sander, C., Weinstein, J., Meyerson, M., Gabriel, S., Laird, P. W., Haussler, D., Getz, G. & Chin, L., Apr 24 2014, In : Cell. 157, 3, p. 753 1 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Parametric response maps of perfusion MRI may identify recurrent glioblastomas responsive to bevacizumab and irinotecan

Aquino, D., Di Stefano, A. L., Scotti, A., Cuppini, L., Anghileri, E., Finocchiaro, G., Bruzzone, M. G. & Eoli, M., Mar 27 2014, In : PLoS One. 9, 3, e90535.

Research output: Contribution to journalArticle

irinotecan
blood volume
Glioblastoma
Magnetic resonance imaging
Blood
18 Citations (Scopus)

Perspectives for immunotherapy in glioblastoma treatment

Finocchiaro, G. & Pellegatta, S., 2014, In : Current Opinion in Oncology. 26, 6, p. 608-614 7 p.

Research output: Contribution to journalArticle

Glioblastoma
Immunotherapy
Dendritic Cells
Antigen Receptors
Vaccination