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Research Output 1978 2020

2020

CytoMatrix for a reliable and simple characterization of lung cancer stem cells from malignant pleural effusions

Bruschini, S., di Martino, S., Pisanu, M. E., Fattore, L., De Vitis, C., Laquintana, V., Buglioni, S., Tabbì, E., Cerri, A., Visca, P., Alessandrini, G., Facciolo, F., Napoli, C., Trombetta, M., Santoro, A., Crescenzi, A., Ciliberto, G. & Mancini, R., Mar 1 2020, In : Journal of Cellular Physiology. 235, 3, p. 1877-1887 11 p.

Research output: Contribution to journalArticle

Open Access
Malignant Pleural Effusion
Neoplastic Stem Cells
Stem cells
Stearoyl-CoA Desaturase
Lung Neoplasms
2019

A multicenter REtrospective observational study of first-line treatment with PERtuzumab, trastuzumab and taxanes for advanced HER2 positive breast cancer patients. RePer Study

Gamucci, T., Pizzuti, L., Natoli, C., Mentuccia, L., Sperduti, I., Barba, M., Sergi, D., Iezzi, L., Maugeri-Saccà, M., Vaccaro, A., Magnolfi, E., Gelibter, A., Barchiesi, G., Magri, V., D’Onofrio, L., Cassano, A., Rossi, E., Botticelli, A., Moscetti, L., Omarini, C. & 29 others, Fabbri, M. A., Scinto, A. F., Corsi, D., Carbognin, L., Mazzotta, M., Bria, E., Foglietta, J., Samaritani, R., Garufi, C., Mariani, L., Barni, S., Mirabelli, R., Sarmiento, R., Graziano, V., Santini, D., Marchetti, P., Tonini, G., Di Lauro, L., Sanguineti, G., Paoletti, G., Tomao, S., De Maria, R., Veltri, E., Paris, I., Giotta, F., Latorre, A., Giordano, A., Ciliberto, G. & Vici, P., Feb 1 2019, In : Cancer Biology and Therapy. 20, 2, p. 192-200 9 p.

Research output: Contribution to journalArticle

Taxoids
Observational Studies
Retrospective Studies
Breast Neoplasms
Maintenance

A multicenter REtrospective observational study of first-line treatment with PERtuzumab, trastuzumab and taxanes for advanced HER2 positive breast cancer patients. RePer Study

Gamucci, T., Pizzuti, L., Natoli, C., Mentuccia, L., Sperduti, I., Barba, M., Sergi, D., Iezzi, L., Maugeri-Sacca, M., Vaccaro, A., Magnolfi, E., Gelibter, A., Barchiesi, G., Magri, V., D'Onofrio, L., Cassano, A., Rossi, E., Botticelli, A., Moscetti, L., Omarini, C. & 29 others, Fabbri, M. A., Scinto, A. F., Corsi, D., Carbognin, L., Mazzotta, M., Bria, E., Foglietta, J., Samaritani, R., Garufi, C., Mariani, L., Barni, S., Mirabelli, R., Sarmiento, R., Graziano, V., Santini, D., Marchetti, P., Tonini, G., Di Lauro, L., Sanguineti, G., Paoletti, G., Tomao, S., De Maria, R., Veltri, E., Paris, I., Giotta, F., Latorre, A., Giordano, A., Ciliberto, G. & Vici, P., 2019, In : Cancer Biology and Therapy. 20, 2, p. 192-200 9 p.

Research output: Contribution to journalArticle

B4GALT1 Is a New Candidate to Maintain the Stemness of Lung Cancer Stem Cells

De Vitis, C., Corleone, G., Salvati, V., Ascenzi, F., Pallocca, M., De Nicola, F., Fanciulli, M., di Martino, S., Bruschini, S., Napoli, C., Ricci, A., Bassi, M., Venuta, F., Rendina, E. A., Ciliberto, G. & Mancini, R., 2019, In : Journal of Clinical Medicine. 8, 11

Research output: Contribution to journalArticle

Combinations of immuno-checkpoint inhibitors predictive biomarkers only marginally improve their individual accuracy

Pallocca, M., Angeli, D., Palombo, F., Sperati, F., Milella, M., Goeman, F., De Nicola, F., Fanciulli, M., Nisticò, P., Quintarelli, C. & Ciliberto, G., Apr 23 2019, In : Journal of Translational Medicine. 17, 1, p. 131

Research output: Contribution to journalArticle

Biomarkers
Area Under Curve
Microsatellite Instability
Microsatellite Repeats
Tumors

CytoMatrix for a reliable and simple characterization of lung cancer stem cells from malignant pleural effusions

Bruschini, S., di Martino, S., Pisanu, M. E., Fattore, L., De Vitis, C., Laquintana, V., Buglioni, S., Tabbi, E., Cerri, A., Visca, P., Alessandrini, G., Facciolo, F., Napoli, C., Trombetta, M., Santoro, A., Crescenzi, A., Ciliberto, G. & Mancini, R., 2019, In : Journal of Cellular Physiology. 235 , 3, p. 1877-1887

Research output: Contribution to journalArticle

Distinct HR expression patterns significantly affect the clinical behavior of metastatic HER2+ breast cancer and degree of benefit from novel anti-HER2 agents in the real world setting

Pizzuti, L., Krasniqi, E., Barchiesi, G., Della Giulia, M., Izzo, F., Sanguineti, G., Marchetti, P., Mazzotta, M., Giusti, R., Botticelli, A., Gamucci, T., Natoli, C., Grassadonia, A., Tinari, N., Iezzi, L., Tomao, S., Tomao, F., Tonini, G., Santini, D., Astone, A. & 30 others, Michelotti, A., De Angelis, C., Mentuccia, L., Vaccaro, A., Magnolfi, E., Gelibter, A., Magri, V., Cortesi, E., D'Onofrio, L., Cassano, A., Rossi, E., Cazzaniga, M., Moscetti, L., Omarini, C., Piacentini, F., Fabbri, M. A., Scinto, A. F., Corsi, D., Carbognin, L., Bria, E., La Verde, N., Garufi, C., Paris, I., Giotta, F., Lorusso, V., De Maria, R., Ciliberto, G., Sperduti, I., Barba, M. & Vici, P., Jan 1 2019, (Accepted/In press) In : International Journal of Cancer.

Research output: Contribution to journalArticle

Open Access
Immunohistochemistry
Breast Neoplasms
Neoplasms
Estrogen Receptors
Disease-Free Survival

ErbB3 phosphorylation as central event in adaptive resistance to targeted therapy in metastatic melanoma: Early detection in CTCs during therapy and insights into regulation by autocrine neuregulin

Ruggiero, C. F., Malpicci, D., Fattore, L., Madonna, G., Vanella, V., Mallardo, D., Liguoro, D., Salvati, V., Capone, M., Bedogni, B., Ascierto, P. A., Mancini, R. & Ciliberto, G., Oct 2019, In : Cancers. 11, 10, 1425.

Research output: Contribution to journalArticle

Open Access
Neuregulins
Circulating Neoplastic Cells
Cell- and Tissue-Based Therapy
Melanoma
Phosphorylation

Eribulin in triple negative metastatic breast cancer: Critic interpretation of current evidence and projection for future scenarios

Pizzuti, L., Krasniqi, E., Barchiesi, G., Mazzotta, M., Barba, M., Amodio, A., Massimiani, G., Pelle, F., Kayal, R., Vizza, E., Grassadonia, A., Tomao, S., Venuti, A., Gamucci, T., Marchetti, P., Natoli, C., Sanguineti, G., Ciliberto, G. & Vici, P., Jan 1 2019, In : Journal of Cancer. 10, 24, p. 5903-5914 12 p.

Research output: Contribution to journalReview article

Open Access
eribulin
Triple Negative Breast Neoplasms
Therapeutics
Drug Therapy
Taxoids

Highly durable response to capecitabine in patient with metastatic estrogen receptor positive breast cancer: A case report

Barchiesi, G., Krasniqi, E., Barba, M., Giulia, M. D., Pizzuti, L., Massimiani, G., Ciliberto, G. & Vici, P., Sep 1 2019, In : Medicine (United States). 98, 37, e17135.

Research output: Contribution to journalArticle

Open Access
Estrogen Receptors
Breast Neoplasms
letrozole
Drug Therapy
Disease-Free Survival

Immunotherapy in HER2-positive breast cancer: State of the art and future perspectives

Krasniqi, E., Barchiesi, G., Pizzuti, L., Mazzotta, M., Venuti, A., Maugeri-Saccà, M., Sanguineti, G., Massimiani, G., Sergi, D., Carpano, S., Marchetti, P., Tomao, S., Gamucci, T., De Maria, R., Tomao, F., Natoli, C., Tinari, N., Ciliberto, G., Barba, M. & Vici, P., Oct 29 2019, In : Journal of Hematology and Oncology. 12, 1, 111.

Research output: Contribution to journalReview article

Open Access
Immunotherapy
Breast Neoplasms
Immune System
Tumor-Infiltrating Lymphocytes
Active Immunotherapy

Look for methods, not conclusions

Bassi, R., Bucci, E. M., Calogero, R. A., Carninci, P., Ciliberto, G., Conte, P., De Luca, M., Corbellini, G., Giordano, A., Marchionni, L., Massaro Giordano, G., Parini, A. & Sbardella, G., Dec 1 2019, In : Cell Death and Disease. 10, 12, 931.

Research output: Contribution to journalLetter

Open Access

Mutations in the KEAP1-NFE2L2 Pathway Define a Molecular Subset of Rapidly Progressing Lung Adenocarcinoma

Goeman, F., De Nicola, F., Scalera, S., Sperati, F., Gallo, E., Ciuffreda, L., Pallocca, M., Pizzuti, L., Krasniqi, E., Barchiesi, G., Vici, P., Barba, M., Buglioni, S., Casini, B., Visca, P., Pescarmona, E., Mazzotta, M., De Maria, R., Fanciulli, M., Ciliberto, G. & 1 others, Maugeri-Saccà, M., Nov 2019, In : Journal of Thoracic Oncology. 14, 11, p. 1924-1934 11 p.

Research output: Contribution to journalArticle

Mutation
Genes
Ataxia Telangiectasia
Neoplasms
Kelch-Like ECH-Associated Protein 1

Poly-specific neoantigen-targeted cancer vaccines delay patient derived tumor growth

Aurisicchio, L., Salvatori, E., Lione, L., Bandini, S., Pallocca, M., Maggio, R., Fanciulli, M., De Nicola, F., Goeman, F., Ciliberto, G., Conforti, A., Luberto, L. & Palombo, F., Feb 14 2019, In : Journal of Experimental and Clinical Cancer Research. 38, 1, 78.

Research output: Contribution to journalArticle

Open Access
Cancer Vaccines
Vaccines
Growth
Neoplasms
Electroporation

Predictive signatures inform the effective repurposing of decitabine to treat KRAS-dependent pancreatic ductal adenocarcinoma

Mottini, C., Tomihara, H., Carrella, D., Lamolinara, A., Iezzi, M., Huang, J. K., Amoreo, C. A., Buglioni, S., Manni, I., Robinson, F. S., Minelli, R., Kang, Y., Fleming, J. B., Kim, M. P., Bristow, C. A., Trisciuoglio, D., Iuliano, A., Bufalo, D. D., Bernardo, D. D., Melisi, D. & 4 others, Draetta, G. F., Ciliberto, G., Carugo, A. & Cardone, L., Nov 1 2019, In : Cancer Research. 79, 21, p. 5612-5625 14 p.

Research output: Contribution to journalArticle

Open Access
decitabine
Adenocarcinoma
Pancreatic Neoplasms
Drug Repositioning
Neoplasms

Prognostic relevance of DNA damage and repair biomarkers in elderly patients with hormone-receptor-positive breast cancer treated with neoadjuvant hormone therapy: evidence from the real-world setting

Di Benedetto, A., Ercolani, C., Pizzuti, L., Angelucci, D., Sergi, D., Marinelli, C., Iezzi, L., Sperati, F., Terrenato, I., Mazzotta, M., Mariani, L., Vizza, E., Paoletti, G., Tomao, S., Maugeri-Saccà, M., Barba, M., Tinari, N., Natoli, C., Ciliberto, G., Grassadonia, A. & 1 others, Vici, P., Aug 1 2019, In : Therapeutic Advances in Medical Oncology. 11

Research output: Contribution to journalArticle

Open Access
Neoadjuvant Therapy
DNA Repair
DNA Damage
Biomarkers
Hormones

Reprogramming miRNAs global expression orchestrates development of drug resistance in BRAF mutated melanoma

Fattore, L., Ruggiero, C. F., Pisanu, M. E., Liguoro, D., Cerri, A., Costantini, S., Capone, F., Acunzo, M., Romano, G., Nigita, G., Mallardo, D., Ragone, C., Carriero, M. V., Budillon, A., Botti, G., Ascierto, P. A., Mancini, R. & Ciliberto, G., 2019, In : Cell Death and Differentiation. 26, 7, p. 1267-1282 16 p.

Research output: Contribution to journalArticle

Single cell analysis to dissect molecular heterogeneity and disease evolution in metastatic melanoma

Fattore, L., Ruggiero, C. F., Liguoro, D., Mancini, R. & Ciliberto, G., Nov 1 2019, In : Cell Death and Disease. 10, 11, 827.

Research output: Contribution to journalReview article

Open Access
Single-Cell Analysis
Melanoma
Neoplasms
Clonal Evolution
Tumor Microenvironment
Formyl Peptide Receptor
Urokinase-Type Plasminogen Activator
Peptides
Chemical activation
N-Formylmethionine Leucyl-Phenylalanine

The potential of BRAF-associated non-coding RNA as a therapeutic target in melanoma

Fattore, L., Mancini, R., Ascierto, P. A. & Ciliberto, G., Jan 2 2019, In : Expert Opinion on Therapeutic Targets. 23, 1, p. 53-68 16 p.

Research output: Contribution to journalArticle

Untranslated RNA
Melanoma
Deregulation
Expert Testimony
Therapeutics

Toward a comprehensive view of cancer immune responsiveness: A synopsis from the SITC workshop

Bedognetti, D., Ceccarelli, M., Galluzzi, L., Lu, R., Palucka, K., Samayoa, J., Spranger, S., Warren, S., Wong, K. K., Ziv, E., Chowell, D., Coussens, L. M., De Carvalho, D. D., Denardo, D. G., Galon, J., Kaufman, H. L., Kirchhoff, T., Lotze, M. T., Luke, J. J., Minn, A. J. & 34 others, Politi, K., Shultz, L. D., Simon, R., Thórsson, V., Weidhaas, J. B., Ascierto, M. L., Ascierto, P. A., Barnes, J. M., Barsan, V., Bommareddy, P. K., Bot, A., Church, S. E., Ciliberto, G., De Maria, A., Draganov, D., Ho, W. S., McGee, H. M., Monette, A., Murphy, J. F., Nisticò, P., Park, W., Patel, M., Quigley, M., Radvanyi, L., Raftopoulos, H., Rudqvist, N. P., Snyder, A., Sweis, R. F., Valpione, S., Butterfield, L. H., Disis, M. L., Fox, B. A., Cesano, A. & Marincola, F. M., May 22 2019, In : Journal for ImmunoTherapy of Cancer. 7, 1, 131.

Research output: Contribution to journalReview article

Open Access
Immunotherapy
Education
Neoplasms
Advisory Committees
Allergy and Immunology

Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop

Bedognetti, D., Ceccarelli, M., Galluzzi, L., Lu, R., Palucka, K., Samayoa, J., Spranger, S., Warren, S., Wong, K. K., Ziv, E., Chowell, D., Coussens, L. M., De Carvalho, D. D., DeNardo, D. G., Galon, J., Kaufman, H. L., Kirchhoff, T., Lotze, M. T., Luke, J. J., Minn, A. J. & 36 others, Politi, K., Shultz, L. D., Simon, R., Thorsson, V., Weidhaas, J. B., Ascierto, M. L., Ascierto, P. A., Barnes, J. M., Barsan, V., Bommareddy, P. K., Bot, A., Church, S. E., Ciliberto, G., De Maria, A., Draganov, D., Ho, W. S., McGee, H. M., Monette, A., Murphy, J. F., Nistico, P., Park, W., Patel, M., Quigley, M., Radvanyi, L., Raftopoulos, H., Rudqvist, N. P., Snyder, A., Sweis, R. F., Valpione, S., Zappasodi, R., Butterfield, L. H., Disis, M. L., Fox, B. A., Cesano, A., Marincola, F. M. & Groups, S. F. I. O. C. SITC. C. I. R. T. F. A. W., 2019, In : Journal for ImmunoTherapy of Cancer. 7, 1, p. 131

Research output: Contribution to journalArticle

2018

A multicenter REtrospective observational study of first-line treatment with PERtuzumab, trastuzumab and taxanes for advanced HER2 positive breast cancer patients. RePer Study

Gamucci, T., Pizzuti, L., Natoli, C., Mentuccia, L., Sperduti, I., Barba, M., Sergi, D., Iezzi, L., Maugeri-Saccà, M., Vaccaro, A., Magnolfi, E., Gelibter, A., Barchiesi, G., Magri, V., D'Onofrio, L., Cassano, A., Rossi, E., Botticelli, A., Moscetti, L., Omarini, C. & 29 others, Fabbri, M. A., Scinto, A. F., Corsi, D., Carbognin, L., Mazzotta, M., Bria, E., Foglietta, J., Samaritani, R., Garufi, C., Mariani, L., Barni, S., Mirabelli, R., Sarmiento, R., Graziano, V., Santini, D., Marchetti, P., Tonini, G., Di Lauro, L., Sanguineti, G., Paoletti, G., Tomao, S., De Maria, R., Veltri, E., Paris, I., Giotta, F., Latorre, A., Giordano, A., Ciliberto, G. & Vici, P., Nov 7 2018, In : Cancer Biology and Therapy. p. 1-9 9 p.

Research output: Contribution to journalArticle

Taxoids
Observational Studies
Retrospective Studies
Breast Neoplasms
Maintenance

Antigen-specificity and DTIC before peptide-vaccination differently shape immune-checkpoint expression pattern, anti-tumor functionality and TCR repertoire in melanoma patients

Palermo, B., Franzese, O., Donna, C. D., Panetta, M., Quintarelli, C., Sperduti, I., Gualtieri, N., Foddai, M. L., Proietti, E., Ferraresi, V., Ciliberto, G. & Nisticò, P., Dec 2 2018, In : OncoImmunology. 7, 12, p. e1465163

Research output: Contribution to journalArticle

Dacarbazine
Melanoma
Vaccination
T-Lymphocytes
MART-1 Antigen

Antigen-specificity and DTIC before peptide-vaccination differently shape immune-checkpoint expression pattern, anti-tumor functionality and TCR repertoire in melanoma patients

Palermo, B., Franzese, O., Donna, C. D., Panetta, M., Quintarelli, C., Sperduti, I., Gualtieri, N., Foddai, M. L., Proietti, E., Ferraresi, V., Ciliberto, G. & Nisticò, P., Sep 11 2018, In : OncoImmunology. 7, 12, p. e1465163 13 p.

Research output: Contribution to journalArticle

Dacarbazine
Melanoma
Vaccination
T-Lymphocytes
MART-1 Antigen

Body mass index in HER2-negative metastatic breast cancer treated with first-line paclitaxel and bevacizumab

Pizzuti, L., Sergi, D., Sperduti, I., Lauro, L. D., Mazzotta, M., Botti, C., Izzo, F., Marchetti, L., Tomao, S., Marchetti, P., Natoli, C., Grassadonia, A., Gamucci, T., Mentuccia, L., Magnolfi, E., Vaccaro, A., Cassano, A., Rossi, E., Botticelli, A., Sini, V. & 13 others, Sarobba, M. G., Fabbri, M. A., Moscetti, L., Astone, A., Michelotti, A., De Angelis, C., Bertolini, I., Angelini, F., Ciliberto, G., Maugeri-Saccà, M., Giordano, A., Barba, M. & Vici, P., Feb 9 2018, (Accepted/In press) In : Cancer Biology and Therapy. p. 1-7 7 p.

Research output: Contribution to journalArticle

Paclitaxel
Body Mass Index
Breast Neoplasms
Disease-Free Survival
Survival

Coexisting YAP expression and TP53 missense mutations delineates a molecular scenario unexpectedly associated with better survival outcomes in advanced gastric cancer

Pallocca, M., Goeman, F., de Nicola, F., Melucci, E., Sperati, F., Terrenato, I., Pizzuti, L., Casini, B., Gallo, E., Amoreo, C. A., Vici, P., di Lauro, L., Buglioni, S., Diodoro, M. G., Pescarmona, E., Mazzotta, M., Barba, M., Fanciulli, M., de Maria, R., Ciliberto, G. & 1 others, Maugeri-Saccà, M., Sep 4 2018, In : Journal of Translational Medicine. 16, 1, p. 247

Research output: Contribution to journalComment/debate

Chemotherapy
Missense Mutation
Stomach Neoplasms
Mutation
Survival

Deep sequencing and pathway-focused analysis revealed multigene oncodriver signatures predicting survival outcomes in advanced colorectal cancer

De Nicola, F., Goeman, F., Pallocca, M., Sperati, F., Pizzuti, L., Melucci, E., Casini, B., Amoreo, C. A., Gallo, E., Diodoro, M. G., Buglioni, S., Mazzotta, M., Vici, P., Sergi, D., Di Lauro, L., Barba, M., Pescarmona, E., Ciliberto, G., De Maria, R., Fanciulli, M. & 1 others, Maugeri-Saccà, M., Jul 1 2018, In : Oncogenesis. 7, 7, p. 55

Research output: Contribution to journalArticle

High-Throughput Nucleotide Sequencing
Colorectal Neoplasms
Mutation
Survival
Genes

Expression of the Hippo transducer TAZ in association with WNT pathway mutations impacts survival outcomes in advanced gastric cancer patients treated with first-line chemotherapy

Melucci, E., Casini, B., Ronchetti, L., Pizzuti, L., Sperati, F., Pallocca, M., De Nicola, F., Goeman, F., Gallo, E., Amoreo, C. A., Sergi, D., Terrenato, I., Vici, P., Di Lauro, L., Diodoro, M. G., Pescarmona, E., Barba, M., Mazzotta, M., Mottolese, M., Fanciulli, M. & 4 others, Ciliberto, G., De Maria, R., Buglioni, S. & Maugeri-Saccà, M., Feb 5 2018, In : Journal of Translational Medicine. 16, 1, p. 22

Research output: Contribution to journalArticle

Chemotherapy
Crosstalk
Transducers
Stomach Neoplasms
Wnt Signaling Pathway

HSP90 inhibition alters the chemotherapy-driven rearrangement of the oncogenic secretome

Di Martino, S., Amoreo, C. A., Nuvoli, B., Galati, R., Strano, S., Facciolo, F., Alessandrini, G., Pass, H. I., Ciliberto, G., Blandino, G., De Maria, R. & Cioce, M., Mar 1 2018, In : Oncogene. 37, 10, p. 1369-1385 17 p.

Research output: Contribution to journalArticle

Interleukin-8
Drug Therapy
Phenotype
Neoplasms
Mesothelioma

Identifying a panel of genes/proteins/miRNAs modulated by arsenicals in bladder, prostate, kidney cancers

Polo, A., Marchese, S., Petro, G. D., Montella, M., Ciliberto, G., Budillon, A. & Costantini, S., Jul 10 2018, In : Scientific Reports. 8, 1, p. 10395

Research output: Contribution to journalArticle

Arsenicals
Kidney Neoplasms
MicroRNAs
Prostatic Neoplasms
Urinary Bladder

Inhibition of Stearoyl-CoA desaturase 1 reverts BRAF and MEK inhibition-induced selection of cancer stem cells in BRAF-mutated melanoma

Pisanu, M. E., Bruschini, S., Tabbì, E., Jakopin, Z., Cippitelli, C., Bartolazzi, A., Raffa, S., Torrisi, M. R., Ascierto, P. A., Ciliberto, G. & Mancini, R., Dec 17 2018, In : Journal of Experimental and Clinical Cancer Research. 37, 1, p. 318

Research output: Contribution to journalArticle

International validation of the consensus Immunoscore for the classification of colon cancer

Pagès, F., Mlecnik, B., Marliot, F., Bindea, G., Ou, F. S., Bifulco, C., Lugli, A., Zlobec, I., Rau, T. T., Berger, M. D., Nagtegaal, I. D., Vink-Börger, E., Hartmann, A., Geppert, C., Kolwelter, J., Merkel, S., Grützmann, R., Van den Eynde, M., Jouret-Mourin, A., Kartheuser, A. & 30 others, Léonard, D., Remue, C., Wang, J. Y., Bavi, P., Roehrl, M. H. A., Ohashi, P. S., Nguyen, L. T., Han, S. J., MacGregor, H. L., Hafezi-Bakhtiari, S., Wouters, B. G., Masucci, G. V., Andersson, E. K., Zavadova, E., Vocka, M., Spacek, J., Petruzelka, L., Konopasek, B., Dundr, P., Skalova, H., Nemejcova, K., Botti, G., Tatangelo, F., Delrio, P., Ciliberto, G., Maio, M., Laghi, L., Grizzi, F., Fredriksen, T. & Ascierto, P. A., 2018, In : The Lancet.

Research output: Contribution to journalArticle

International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study

Pagès, F., Mlecnik, B., Marliot, F., Bindea, G., Ou, F-S., Bifulco, C., Lugli, A., Zlobec, I., Rau, T. T., Berger, M. D., Nagtegaal, I. D., Vink-Börger, E., Hartmann, A., Geppert, C., Kolwelter, J., Merkel, S., Grützmann, R., Van den Eynde, M., Jouret-Mourin, A., Kartheuser, A. & 79 others, Léonard, D., Remue, C., Wang, J. Y., Bavi, P., Roehrl, M. H. A., Ohashi, P. S., Nguyen, L. T., Han, S., MacGregor, H. L., Hafezi-Bakhtiari, S., Wouters, B. G., Masucci, G. V., Andersson, E. K., Zavadova, E., Vocka, M., Spacek, J., Petruzelka, L., Konopasek, B., Dundr, P., Skalova, H., Nemejcova, K., Botti, G., Tatangelo, F., Delrio, P., Ciliberto, G., Maio, M., Laghi, L., Grizzi, F., Fredriksen, T., Buttard, B., Angelova, M., Vasaturo, A., Maby, P., Church, S. E., Angell, H. K., Lafontaine, L., Bruni, D., El Sissy, C., Haicheur, N., Kirilovsky, A., Berger, A., Lagorce, C., Meyers, J. P., Paustian, C., Feng, Z., Ballesteros-Merino, C., Dijkstra, J., van de Water, C., van Lent-van Vliet, S., Knijn, N., Mușină, A-M., Scripcariu, D-V., Popivanova, B., Xu, M., Fujita, T., Hazama, S., Suzuki, N., Nagano, H., Okuno, K., Torigoe, T., Sato, N., Furuhata, T., Takemasa, I., Itoh, K., Patel, P. S., Vora, H. H., Shah, B., Patel, J. B., Rajvik, K. N., Pandya, S. J., Shukla, S. N., Wang, Y., Zhang, G., Kawakami, Y., Marincola, F. M., Ascierto, P. A., Sargent, D. J., Fox, B. A. & Galon, J., May 26 2018, In : Lancet (London, England). 391, 10135, p. 2128-2139 12 p.

Research output: Contribution to journalArticle

Colonic Neoplasms
Neoplasms
Recurrence
Colon
Neoplasm Staging

Metabolic features of cancer stem cells: the emerging role of lipid metabolism

Mancini, R., Noto, A., Pisanu, M. E., de Vitis, C., Maugeri-Saccà, M. & Ciliberto, G., Feb 15 2018, (Accepted/In press) In : Oncogene. p. 1-12 12 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Lipid Metabolism
Stearoyl-CoA Desaturase
Coenzyme A
Neoplasms

Neoadjuvant chemotherapy in triple-negative breast cancer: A multicentric retrospective observational study in real-life setting

Gamucci, T., Pizzuti, L., Sperduti, I., Mentuccia, L., Vaccaro, A., Moscetti, L., Marchetti, P., Carbognin, L., Michelotti, A., Iezzi, L., Cassano, A., Grassadonia, A., Astone, A., Botticelli, A., Magnolfi, E., Di Lauro, L., Sergi, D., Fuso, P., Tinari, N., Barba, M. & 10 others, Maugeri-Saccà, M., Landucci, E., Conti, F., Sanguineti, G., De Tursi, M., Iafrate, G., Giordano, A., Ciliberto, G., Natoli, C. & Vici, P., Mar 1 2018, In : Journal of Cellular Physiology. 233, 3, p. 2313-2323 11 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Chemotherapy
Anthracyclines
Observational Studies
Retrospective Studies

Observational study of coagulation activation in early breast cancer: Development of a prognostic model based on data from the real world setting

Mandoj, C., Pizzuti, L., Sergi, D., Sperduti, I., Mazzotta, M., Di Lauro, L., Amodio, A., Carpano, S., Di Benedetto, A., Botti, C., Ferranti, F., Antenucci, A., D'Alessandro, M. G., Marchetti, P., Tomao, S., Sanguineti, G., Giordano, A., Maugeri-Saccà, M., Ciliberto, G., Conti, L. & 2 others, Vici, P. & Barba, M., May 16 2018, In : Journal of Translational Medicine. 16, 1, 129.

Research output: Contribution to journalArticle

Factor VIII
Coagulation
Observational Studies
Chemical activation
Breast Neoplasms

Palbociclib plus endocrine therapy in HER2 negative, hormonal receptor-positive, advanced breast cancer: A real-world experience

Pizzuti, L., Giordano, A., Michelotti, A., Mazzotta, M., Natoli, C., Gamucci, T., De Angelis, C., Landucci, E., Diodati, L., Iezzi, L., Mentuccia, L., Fabbri, A., Barba, M., Sanguineti, G., Marchetti, P., Tomao, S., Mariani, L., Paris, I., Lorusso, V., Vallarelli, S. & 30 others, Cassano, A., Airoldi, F., Orlandi, A., Moscetti, L., Sergi, D., Sarobba, M. G., Tonini, G., Santini, D., Sini, V., Veltri, E., Vaccaro, A., Ferrari, L., De Tursi, M., Tinari, N., Grassadonia, A., Greco, F., Botticelli, A., La Verde, N., Zamagni, C., Rubino, D., Cortesi, E., Magri, V., Pomati, G., Cazzaniga, M., Mancini, M., Carpano, S., De Maria, R., Sperduti, I., Ciliberto, G. & Vici, P., Jan 1 2018, (Accepted/In press) In : Journal of Cellular Physiology.

Research output: Contribution to journalArticle

exemestane
Confidence Intervals
Breast Neoplasms
Toxicity
Therapeutics

Perspectives in melanoma: Meeting report from the Melanoma Bridge (30 November-2 December, 2017, Naples, Italy)

Ascierto, P. A., Puzanov, I., Agarwala, S. S., Bifulco, C., Botti, G., Caracò, C., Ciliberto, G., Davies, M. A., Dummer, R., Ferrone, S., Gajewski, T. F., Garbe, C., Luke, J. J., Marincola, F. M., Masucci, G., Mehnert, J. M., Mozzillo, N., Palmieri, G., Postow, M. A., Schoenberger, S. P. & 2 others, Wang, E. & Thurin, M., Jul 21 2018, In : Journal of Translational Medicine. 16, 1, 207.

Research output: Contribution to journalArticle

Italy
Tumors
Melanoma
Proto-Oncogene Proteins B-raf
T-cells

Perspectives in melanoma

Ascierto, P. A., Puzanov, I., Agarwala, S. S., Bifulco, C., Botti, G., Caracò, C., Ciliberto, G., Davies, M. A., Dummer, R., Ferrone, S., Gajewski, T. F., Garbe, C., Luke, J. J., Marincola, F. M., Masucci, G., Mehnert, J. M., Mozzillo, N., Palmieri, G., Postow, M. A., Schoenberger, S. P. & 2 others, Wang, E. & Thurin, M., Jul 21 2018, In : Journal of Translational Medicine. 16, 1

Research output: Contribution to journalArticle

Reprogramming miRNAs global expression orchestrates development of drug resistance in BRAF mutated melanoma

Fattore, L., Ruggiero, C. F., Pisanu, M. E., Liguoro, D., Cerri, A., Costantini, S., Capone, F., Acunzo, M., Romano, G., Nigita, G., Mallardo, D., Ragone, C., Carriero, M. V., Budillon, A., Botti, G., Ascierto, P. A., Mancini, R. & Ciliberto, G., Jan 1 2018, (Accepted/In press) In : Cell Death and Differentiation.

Research output: Contribution to journalArticle

MicroRNAs
Drug Resistance
Melanoma
Recurrence
Mitogen-Activated Protein Kinase Kinases
Lymphoma, Large B-Cell, Diffuse
MicroRNAs
Serum
Biomarkers
Atlases
United States Food and Drug Administration
Neoplasms
Systems Biology
Standard of Care
Genomics

Tel-eVax: a genetic vaccine targeting telomerase for treatment of canine lymphoma

Impellizeri, J. A., Gavazza, A., Greissworth, E., Crispo, A., Montella, M., Ciliberto, G., Lubas, G. & Aurisicchio, L., Dec 11 2018, In : Journal of Translational Medicine. 16, 1, p. 349-018-1738-6

Research output: Contribution to journalArticle

Telomerase
Gene transfer
Canidae
Lymphoma
Vaccines

The clinical significance of PD-L1 in advanced gastric cancer is dependent on ARID1A mutations and ATM expression

Buglioni, S., Melucci, E., Sperati, F., Pallocca, M., Terrenato, I., De Nicola, F., Goeman, F., Casini, B., Amoreo, C. A., Gallo, E., Diodoro, M. G., Pescarmona, E., Vici, P., Sergi, D., Pizzuti, L., Di Lauro, L., Mazzotta, M., Barba, M., Fanciulli, M., Vitale, I. & 3 others, De Maria, R., Ciliberto, G. & Maugeri-Saccà, M., Apr 19 2018, (Accepted/In press) In : OncoImmunology.

Research output: Contribution to journalArticle

Stomach Neoplasms
DNA Repair
DNA Damage
Mutation
Survival

The perfect personalized cancer therapy: Cancer vaccines against neoantigens

Aurisicchio, L., Pallocca, M., Ciliberto, G. & Palombo, F., Apr 20 2018, In : Journal of Experimental and Clinical Cancer Research. 37, 1, 86.

Research output: Contribution to journalReview article

Cancer Vaccines
Computational Biology
Neoplasms
Therapeutics
Genomics
2017

Analysis of the ATR-Chk1 and ATM-Chk2 pathways in male breast cancer revealed the prognostic significance of ATR expression

Di Benedetto, A., Ercolani, C., Mottolese, M., Sperati, F., Pizzuti, L., Vici, P., Terrenato, I., Shaaban, A. M., Humphries, M. P., Di Lauro, L., Barba, M., Vitale, I., Ciliberto, G., Speirs, V., De Maria, R. & Maugeri-Saccà, M., Dec 1 2017, In : Scientific Reports. 7, 1, 8078.

Research output: Contribution to journalArticle

Male Breast Neoplasms
Survival
DNA Damage
DNA Repair
Survival Analysis

An interaction network approach to study the correlation between endocrine disrupting chemicals and breast cancer

Polo, A., Nittoli, C., Crispo, A., Langastro, T., Cocco, S., Severino, L., Laurentiis, M. D., Ciliberto, G., Montella, M., Budillon, A. & Costantini, S., Nov 21 2017, In : Molecular BioSystems. 13, 12, p. 2687-2696 10 p.

Research output: Contribution to journalArticle

Endocrine Disruptors
Breast Neoplasms
Mycotoxins
Protein Interaction Maps
Proteins

A retrospective multicentric observational study of trastuzumab emtansine in HER2 positive metastatic breast cancer: A real-world experience

Vici, P., Pizzuti, L., Michelotti, A., Sperduti, I., Natoli, C., Mentuccia, L., Di Lauro, L., Sergi, D., Marchetti, P., Santini, D., Magnolfi, E., Iezzi, L., Moscetti, L., Fabbri, A., Cassano, A., Grassadonia, A., Omarini, C., Piacentini, F., Botticelli, A., Bertolini, I. & 28 others, Scinto, A. F., Zampa, G., Mauri, M., D'Onofrio, L., Sini, V., Barba, M., Maugeri-Saccà, M., Rossi, E., Landucci, E., Tomao, S., Alberti, A. M., Giotta, F., Ficorella, C., Adamo, V., Russo, A., Lorusso, V., Cannita, K., Barni, S., Laudadio, L., Greco, F., Garrone, O., Della Giulia, M., Marolla, P., Sanguineti, G., Di Cocco, B., Ciliberto, G., De Maria, R. & Gamucci, T., Jan 1 2017, In : Oncotarget. 8, 34, p. 56921-56931 11 p.

Research output: Contribution to journalArticle

Observational Studies
Breast Neoplasms
Survival
ado-trastuzumab emtansine
pertuzumab

Blockade of Stearoyl-CoA-desaturase 1 activity reverts resistance to cisplatin in lung cancer stem cells

Pisanu, M. E., Noto, A., Vitis, C. D., Morrone, S., Scognamiglio, G., Botti, G., Venuta, F., Diso, D., Jakopin, Z., Padula, F., Ricci, A., Mariotta, S., Giovagnoli, M. R., Giarnieri, E., Amelio, I., Agostini, M., Melino, G., Ciliberto, G. & Mancini, R., Oct 10 2017, In : Cancer Letters. 406, p. 93-104 12 p.

Research output: Contribution to journalArticle

Stearoyl-CoA Desaturase
Neoplastic Stem Cells
Cisplatin
Lung Neoplasms
Up-Regulation