• 32334 Citations
  • 84 h-Index
1978 …2019
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Fingerprint Dive into the research topics where Gerry Melino is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 79 Similar Profiles
Neuroblastoma Medicine & Life Sciences
Apoptosis Medicine & Life Sciences
Protein Isoforms Medicine & Life Sciences
Cell Death Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Ubiquitin-Protein Ligases Medicine & Life Sciences
Proteins Medicine & Life Sciences
Keratinocytes Medicine & Life Sciences

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Research Output 1978 2019

  • 32334 Citations
  • 84 h-Index
  • 540 Article
  • 3 Chapter
  • 3 Review article
  • 2 Conference contribution

A new bioavailable fenretinide formulation with antiproliferative, antimetabolic, and cytotoxic effects on solid tumors

Orienti, I., Francescangeli, F., De Angelis, M. L., Fecchi, K., Bongiorno-Borbone, L., Signore, M., Peschiaroli, A., Boe, A., Bruselles, A., Costantino, A., Eramo, A., Salvati, V., Sette, G., Contavalli, P., Zolla, L., Oki, T., Kitamura, T., Spada, M., Giuliani, A., Baiocchi, M. & 5 others, La Torre, F., Melino, G., Tartaglia, M., De Maria, R. & Zeuner, A., Jul 23 2019, In : Cell death & disease. 10, 7, p. 529

Research output: Contribution to journalArticle

Fenretinide
Biological Availability
Neoplasms
Biological Phenomena
Lipids

Emerging roles of HECT-type E3 ubiquitin ligases in autophagy regulation

Melino, G., Cecconi, F., Pelicci, P. G., Mak, T. W. & Bernassola, F., Oct 2019, In : Molecular Oncology. 13, 10, p. 2033-2048 16 p.

Research output: Contribution to journalReview article

Ubiquitin-Protein Ligases
Autophagy
Protein Unfolding
Ubiquitination
Post Translational Protein Processing

ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP

Bufalieri, F., Infante, P., Bernardi, F., Caimano, M., Romania, P., Moretti, M., Lospinoso Severini, L., Talbot, J., Melaiu, O., Tanori, M., Di Magno, L., Bellavia, D., Capalbo, C., Puget, S., De Smaele, E., Canettieri, G., Guardavaccaro, D., Busino, L., Peschiaroli, A., Pazzaglia, S. & 7 others, Giannini, G., Melino, G., Locatelli, F., Gulino, A., Ayrault, O., Fruci, D. & Di Marcotullio, L., Jul 24 2019, In : Nature Communications. 10, 1, p. 3304

Research output: Contribution to journalArticle

endoplasmic reticulum
Aminopeptidases
Endoplasmic Reticulum
Carcinogenesis
degradation
Mitochondrial Degradation
Glycogen Synthase Kinase 3
Mitochondria
Ubiquitin-Protein Ligases
Proto-Oncogene Proteins c-bcl-2

HUWE1 controls MCL1 stability to unleash AMBRA1-induced mitophagy

Strappazzon, F., Di Rita, A., Peschiaroli, A., Leoncini, P. P., Locatelli, F., Melino, G. & Cecconi, F., Aug 21 2019, In : Cell Death and Differentiation.

Research output: Contribution to journalArticle

Mitochondrial Degradation
Glycogen Synthase Kinase 3
Mitochondria
Ubiquitin-Protein Ligases
Proto-Oncogene Proteins c-bcl-2