1979 …2020

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Biophysical and in Vivo Studies Identify a New Natural-Based Polyphenol, Counteracting Aβ Oligomerization in Vitro and Aβ Oligomer-Mediated Memory Impairment and Neuroinflammation in an Acute Mouse Model of Alzheimer's Disease

Tomaselli, S., La Vitola, P., Pagano, K., Brandi, E., Santamaria, G., Galante, D., D'Arrigo, C., Moni, L., Lambruschini, C., Banfi, L., Lucchetti, J., Fracasso, C., Molinari, H., Forloni, G., Balducci, C. & Ragona, L., Nov 20 2019, In : ACS Chemical Neuroscience. 10, 11, p. 4462-4475 14 p.

Research output: Contribution to journalArticle

Blocking ADAM10 synaptic trafficking generates a model of sporadic Alzheimer's disease

Epis, R., Marcello, E., Gardoni, F., Vastagh, C., Malinverno, M., Balducci, C., Colombo, A., Borroni, B., Vara, H., Dell'Agli, M., Cattabeni, F., Giustetto, M., Borsello, T., Forloni, G., Padovani, A. & Di Luca, M., Nov 2010, In : Brain. 133, 11, p. 3323-3335 13 p.

Research output: Contribution to journalArticle

Body mass index, cognition, disability, APOE genotype, and mortality: The "treviso longeva" study

Gustafson, D. R., Mazzuco, S., Ongaro, F., Antuono, P., Forloni, G., Albani, D., Gajo, G. B., Durante, E., Caberlotto, L., Zanardo, A., Siculi, M. & Gallucci, M., Jul 2012, In : American Journal of Geriatric Psychiatry. 20, 7, p. 594-602 9 p.

Research output: Contribution to journalArticle

Body mass index, lifestyles, physical performance and cognitive decline: The "treviso Longeva (Trelong)" study

Gallucci, M., Mazzuco, S., Ongaro, F., Di Giorgi, E., Mecocci, P., Cesari, M., Albani, D., Forloni, G. L., Durante, E., Gajo, G. B., Zanardo, A., Siculi, M., Caberlotto, L. & Regini, C., Apr 2013, In : Journal of Nutrition, Health and Aging. 17, 4, p. 378-384 7 p.

Research output: Contribution to journalArticle

Brain aging and dementia during the transition from late adulthood to old age: Design and methodology of the "invece.Ab" population-based study

Guaita, A., Colombo, M., Vaccaro, R., Fossi, S., Vitali, S. F., Forloni, G., Polito, L., Davin, A., Ferretti, V. V. & Villani, S., 2013, In : BMC Geriatrics. 13, 1, 98.

Research output: Contribution to journalArticle

C9ORF72 hexanucleotide repeat number in frontotemporal lobar degeneration: A genotype-phenotype correlation study

Benussi, L., Rossi, G., Glionna, M., Tonoli, E., Piccoli, E., Fostinelli, S., Paterlini, A., Flocco, R., Albani, D., Pantieri, R., Cereda, C., Forloni, G., Tagliavini, F., Binetti, G. & Ghidoni, R., 2014, In : Journal of Alzheimer's Disease. 38, 4, p. 799-808 10 p.

Research output: Contribution to journalArticle

Calcitonin gene-related peptide receptor expression in the neurons and glia of developing rat cerebellum: an autoradiographic and immunohistochemical analysis

Morara, S., Rosina, A., Provini, L., Forloni, G., Caretti, A. & Wimalawansa, S. J., Sep 14 2000, In : Neuroscience. 100, 2, p. 381-391 11 p.

Research output: Contribution to journalArticle

Calcium-dependent evoked release of N-[3H]acetylaspartylglutamate from the optic pathway

Tsai, G., Forloni, G., Robinson, M. B., Stauch, B. L. & Coyle, J. T., 1988, In : Journal of Neurochemistry. 51, 6, p. 1956-1959 4 p.

Research output: Contribution to journalArticle

Candidate gene analysis of IP-10 gene in patients with Alzheimer's disease

Venturelli, E., Galimberti, D., Fenoglio, C., Lovati, C., Finazzi, D., Guidi, I., Corrà, B., Scalabrini, D., Clerici, F., Mariani, C., Forloni, G., Bresolin, N. & Scarpini, E., Aug 14 2006, In : Neuroscience Letters. 404, 1-2, p. 217-221 5 p.

Research output: Contribution to journalArticle

Caspase-3 activation by β-amyloid and prion protein peptides is independent from their neurotoxic effect

Sáez-Valero, J., Angeretti, N. & Forloni, G., Nov 3 2000, In : Neuroscience Letters. 293, 3, p. 207-210 4 p.

Research output: Contribution to journalArticle

CCR2-64I polymorphism and CCR5Δ32 deletion in patients with Alzheimer's disease

Galimberti, D., Fenoglio, C., Lovati, C., Gatti, A., Guidi, I., Venturelli, E., Cutter, G. R., Mariani, C., Forloni, G., Pettenati, C., Baron, P., Conti, G., Bresolin, N. & Scarpini, E., Oct 15 2004, In : Journal of the Neurological Sciences. 225, 1-2, p. 79-83 5 p.

Research output: Contribution to journalArticle

Cell type-specific neuroprotective activity of untranslocated prion protein

Restelli, E., Fioriti, L., Mantovani, S., Airaghi, S., Forloni, G. & Chiesa, R., 2010, In : PLoS One. 5, 10, e13725.

Research output: Contribution to journalArticle

Channels formed with a mutant prion protein PrP(82-146) homologous to a 7-kDa fragment in diseased brain of GSS patients

Bahadi, R., Farrelly, P. V., Kenna, B. L., Kourie, J. I., Tagliavini, F., Forloni, G. & Salmona, M., Oct 1 2003, In : American Journal of Physiology - Cell Physiology. 285, 4 54-4

Research output: Contribution to journalArticle

Characterization of the alpha adrenergic receptor population in hippocampus up regulated by serotonergic raphe deafferentiation

Wang, J. X., Consolo, S., Vinci, R., Forloni, G. L. & Ladinsky, H., Jan 21 1985, In : Life Sciences. 36, 3, p. 255-270 16 p.

Research output: Contribution to journalArticle

Chemical and pharmacological characterization of galanthamine, an acetylcholinesterase inhibitor, and its derivatives. A potential application in Alzheimer's disease?

Han, SY., Sweeney, JE., Bachman, ES., Schweiger, EJ., Forloni, G., Coyle, JT., Davis, BM. & Joullié, MM., 1992, In : European Journal of Medicinal Chemistry. 27, 7, p. 673-687 15 p.

Research output: Contribution to journalArticle

Chemical exchange saturation transfer MRI shows low cerebral 2-deoxy-D-glucose uptake in a model of Alzheimer's Disease

Tolomeo, D., Micotti, E., Serra, S. C., Chappell, M., Snellman, A. & Forloni, G., Jun 22 2018, In : Scientific Reports. 8, 1, p. 9576

Research output: Contribution to journalArticle

Cholesterol decreases secretion of the secreted form of amyloid precursor protein by interfering with glycosylation in the protein secretory pathway

Galbete, J. L., Rodriguez-Martin, T., Peressini, E., Modena, P., Bianchi, R. & Forloni, G., Jun 1 2000, In : Biochemical Journal. 348, 2, p. 307-313 7 p.

Research output: Contribution to journalArticle

Cholinergic neurons of the pontomesencephalic tegmentum release acetylcholine in the basal nuclear complex of freely moving rats

Consolo, S., Bertorelli, R., Forloni, G. L. & Butcher, L. L., 1990, In : Neuroscience. 37, 3, p. 717-723 7 p.

Research output: Contribution to journalArticle

CHRNA7 Gene and Response to Cholinesterase Inhibitors in an Italian Cohort of Alzheimer's Disease Patients

Clarelli, F., Mascia, E., Santangelo, R., Mazzeo, S., Giacalone, G., Galimberti, D., Fusco, F., Zuffi, M., Fenoglio, C., Franceschi, M., Scarpini, E., Forloni, G., Magnani, G., Comi, G., Albani, D. & Martinelli Boneschi, F., 2016, In : Journal of Alzheimer's Disease. 52, 4, p. 1203-1208 6 p.

Research output: Contribution to journalArticle

CHRNA7 Gene and Response to Cholinesterase Inhibitors in an Italian Cohort of Alzheimer's Disease Patients

Clarelli, F., Mascia, E., Santangelo, R., Mazzeo, S., Giacalone, G., Galimberti, D., Fusco, F., Zuffi, M., Fenoglio, C., Franceschi, M., Scarpini, E. A., Forloni, G., Magnani, G., Comi, G., Albani, D. & Martinelli Boneschi, F., 2016, In : Journal of Alzheimer's Disease. 52, 4, p. 1203-1208 6 p.

Research output: Contribution to journalArticle

CHRNA7 Gene and Response to Cholinesterase Inhibitors in an Italian Cohort of Alzheimer's Disease Patients

Clarelli, F., Mascia, E., Santangelo, R., Mazzeo, S., Giacalone, G., Galimberti, D., Fusco, F., Zuffi, M., Fenoglio, C., Franceschi, M., Scarpini, E. A., Forloni, G., Magnani, G., Comi, G., Albani, D. & Martinelli Boneschi, F., 2016, In : Journal of Alzheimer's Disease. 52, 4, p. 1203-1208 6 p.

Research output: Contribution to journalArticle

Chronic infusion of quinolinic acid in rat striatum: effects on discrete neuronal populations

Forloni, G. L., Angeretti, N., Rizzi, M. & Vezzani, A., 1992, In : Journal of the Neurological Sciences. 108, 2, p. 129-136 8 p.

Research output: Contribution to journalArticle

c-Jun N-terminal kinase regulates soluble Aβ oligomers and cognitive impairment in AD mouse model

Sclip, A., Antoniou, X., Colombo, A., Camici, G. G., Pozzi, L., Cardinetti, D., Feligioni, M., Veglianese, P., Bahlmann, F. H., Cervo, L., Balducci, C., Costa, C., Tozzi, A., Calabresi, P., Forloni, G. & Borsello, T., Dec 23 2011, In : Journal of Biological Chemistry. 286, 51, p. 43871-43880 10 p.

Research output: Contribution to journalArticle

Clinical and biomarker profiling of prodromal Alzheimer's disease in workpackage 5 of the Innovative Medicines Initiative PharmaCog project: A 'European ADNI study'

Galluzzi, S., Marizzoni, M., Babiloni, C., Albani, D., Antelmi, L., Bagnoli, C., Bartrés-Faz, D., Cordone, S., Didic, M., Farotti, L., Fiedler, U., Forloni, G., Girtler, N., Hensch, T., Jovicich, J., Leeuwis, A., Marra, C., Molinuevo, J. L., Nobili, F., Pariente, J. & 15 others, Parnetti, L., Payoux, P., Del Percio, C., Ranjeva, J. P., Rolandi, E., Rossini, P. M., Schönknecht, P., Soricelli, A., Tsolaki, M., Visser, P. J., Wiltfang, J., Richardson, J., Bordet, R., Blin, O. J. & Frisoni, G. B., 2016, In : Journal of Internal Medicine. 279, p. 576-591

Research output: Contribution to journalArticle

Clinical and biomarker profiling of prodromal Alzheimer's disease in workpackage 5 of the Innovative Medicines Initiative PharmaCog project: A 'European ADNI study'

Galluzzi, S., Marizzoni, M., Babiloni, C., Albani, D., Antelmi, L., Bagnoli, C., Bartrés-Faz, D., Cordone, S., Didic, M., Farotti, L., Fiedler, U., Forloni, G., Girtler, N., Hensch, T., Jovicich, J., Leeuwis, A., Marra, C., Molinuevo, J. L., Nobili, F., Pariente, J. & 15 others, Parnetti, L., Payoux, P., Del Percio, C., Ranjeva, J. P., Rolandi, E., Rossini, P. M., Schönknecht, P., Soricelli, A., Tsolaki, M., Visser, P. J., Wiltfang, J., Richardson, J., Bordet, R., Blin, O. J. & Frisoni, G. B., 2016, (Accepted/In press) In : Journal of Internal Medicine.

Research output: Contribution to journalArticle

Clinical and biomarker profiling of prodromal Alzheimer's disease in workpackage 5 of the Innovative Medicines Initiative PharmaCog project: A 'European ADNI study'

Galluzzi, S., Marizzoni, M., Babiloni, C., Albani, D., Antelmi, L., Bagnoli, C., Bartrés-Faz, D., Cordone, S., Didic, M., Farotti, L., Fiedler, U., Forloni, G., Girtler, N., Hensch, T., Jovicich, J., Leeuwis, A., Marra, C., Molinuevo, J. L., Nobili, F., Pariente, J. & 15 others, Parnetti, L., Payoux, P., Del Percio, C., Ranjeva, J. P., Rolandi, E., Rossini, P. M., Schönknecht, P., Soricelli, A., Tsolaki, M., Visser, P. J., Wiltfang, J., Richardson, J., Bordet, R., Blin, O. J. & Frisoni, G. B., 2016, (Accepted/In press) In : Journal of Internal Medicine.

Research output: Contribution to journalArticle

Clusterin (SGP-2) induction in rat astroglial cells exposed to prion protein fragment 106-126

Chiesa, R., Angeretti, N., Lucca, E., Salmona, M., Tagliavini, F., Bugiani, O. & Forloni, G., 1996, In : European Journal of Neuroscience. 8, 3, p. 589-597 9 p.

Research output: Contribution to journalArticle

Cognitive deficits associated with alteration of synaptic metaplasticity precede plaque deposition in AβPP23 transgenic mice

Balducci, C., Tonini, R., Zianni, E., Nazzaro, C., Fiordaliso, F., Salio, M., Vismara, L., Gardoni, F., Di Luca, M., Carli, M. & Forloni, G., 2010, In : Journal of Alzheimer's Disease. 21, 4, p. 1367-1381 15 p.

Research output: Contribution to journalArticle

Co-localization of N-acetyl-aspartyl-glutamate in central cholinergic, noradrenergic, and serotonergic neurons.

Forloni, G., Grzanna, R., Blakely, R. D. & Coyle, J. T., 1987, In : Synapse. 1, 5, p. 455-460 6 p.

Research output: Contribution to journalArticle

Comparative magnetic resonance imaging and histopathological correlates in two SOD1 transgenic mouse models of amyotrophic lateral sclerosis

Caron, I., Micotti, E., Paladini, A., Merlino, G., Plebani, L., Forloni, G., Modo, M. & Bendotti, C., Jul 1 2015, In : PLoS One. 10, 7, e0132159.

Research output: Contribution to journalArticle

Conformational Plasticity of the Gerstmann-Sträussler-Scheinker Disease Peptide as Indicated by Its Multiple Aggregation Pathways

Natalello, A., Prokorov, V. V., Tagliavini, F., Morbin, M., Forloni, G., Beeg, M., Manzoni, C., Colombo, L., Gobbi, M., Salmona, M. & Doglia, S. M., Sep 19 2008, In : Journal of Molecular Biology. 381, 5, p. 1349-1361 13 p.

Research output: Contribution to journalArticle

Conformational polymorphism of the amyloidogenic and neurotoxic peptide homologous to residues 106-126 of the prion protein

De Gioia, L., Selvaggini, C., Ghibaudi, E., Diomede, L., Bugiani, O., Forloni, G., Tagliavini, F. & Salmona, M., Mar 18 1994, In : Journal of Biological Chemistry. 269, 11, p. 7859-7862 4 p.

Research output: Contribution to journalArticle

Corrected QT Interval Prolongation in Psychopharmacological Treatment and Its Modulation by Genetic Variation

Corponi, F., Fabbri, C., Boriani, G., Diemberger, I., Albani, D., Forloni, G. & Serretti, A., 2019, In : Neuropsychobiology. 77, 2, p. 67-72 6 p.

Research output: Contribution to journalArticle

CSF cutoffs for MCI due to AD depend on APOEε4 carrier status

Marizzoni, M., Ferrari, C., Babiloni, C., Albani, D., Barkhof, F., Cavaliere, L., Didic, M., Forloni, G., Fusco, F., Galluzzi, S., Hensch, T., Jovicich, J., Marra, C., Molinuevo, J. L., Nobili, F., Parnetti, L., Payoux, P., Ranjeva, J. P., Ribaldi, F., Rolandi, E. & 10 others, Rossini, P. M., Salvatore, M., Soricelli, A., Tsolaki, M., Visser, P. J., Wiltfang, J., Richardson, J. C., Bordet, R., Blin, O. & Frisoni, G. B., Jan 1 2020, (Accepted/In press) In : Neurobiology of Aging.

Research output: Contribution to journalArticle

CSF cutoffs for MCI due to AD depend on APOEε4 carrier status

Marizzoni, M., Ferrari, C., Babiloni, C., Albani, D., Barkhof, F., Cavaliere, L., Didic, M., Forloni, G., Fusco, F., Galluzzi, S., Hensch, T., Jovicich, J., Marra, C., Molinuevo, J. L., Nobili, F., Parnetti, L., Payoux, P., Ranjeva, J. P., Ribaldi, F., Rolandi, E. & 10 others, Rossini, P. M., Salvatore, M., Soricelli, A., Tsolaki, M., Visser, P. J., Wiltfang, J., Richardson, J. C., Bordet, R., Blin, O. & Frisoni, G. B., Jan 1 2020, In : Neurobiol. Aging.

Research output: Contribution to journalArticle

Culture of dorsal root ganglion neurons from aged rats: Effects of acetyl-l-carnitine and NGF

Manfridi, A., Forloni, G. L., Arrigoni-Martelli, E. & Mancia, M., 1992, In : International Journal of Developmental Neuroscience. 10, 4, p. 321-329 9 p.

Research output: Contribution to journalArticle

Current options for drug delivery to the spinal cord

Rossi, F., Perale, G., Papa, S., Forloni, G. & Veglianese, P., Mar 2013, In : Expert Opinion on Drug Delivery. 10, 3, p. 385-396 12 p.

Research output: Contribution to journalArticle

CXCR4 involvement in neurodegenerative diseases

International FTD-Genomics Consortium (IFGC) , Forloni, G. & Albani, D., Apr 11 2018, In : Translational Psychiatry. 8, 1, p. 73

Research output: Contribution to journalArticle

CXCR4 involvement in neurodegenerative diseases

Bonham, L. W., Karch, C. M., Fan, C. C., Tan, C., Geier, E. G., Wang, Y., Wen, N., Broce, I. J., Li, Y., Barkovich, M. J., Ferrari, R., Hardy, J., Momeni, P., Höglinger, G., Müller, U., Hess, C. P., Sugrue, L. P., Dillon, W. P., Schellenberg, G. D., Miller, B. L. & 158 others, Andreassen, O. A., Dale, A. M., Barkovich, A. J., Yokoyama, J. S., Desikan, R. S., Hernandez, D. G., Nalls, M. A., Rohrer, J. D., Ramasamy, A., Kwok, J. B. J., Dobson-Stone, C., Schofield, P. R., Halliday, G. M., Hodges, J. R., Piguet, O., Bartley, L., Thompson, E., Haan, E., Hernández, I., Ruiz, A., Boada, M., Borroni, B., Padovani, A., Cruchaga, C., Cairns, N. J., Benussi, L., Binetti, G., Ghidoni, R., Forloni, G., Albani, D., Galimberti, D., Fenoglio, C., Serpente, M., Scarpini, E., Clarimón, J., Lleó, A., Blesa, R., Waldö, M. L., Nilsson, K., Nilsson, C., MacKenzie, I. R. A., Hsiung, G-YR., Mann, D. M. A., Grafman, J., Morris, C. M., Attems, J., Griffiths, T. D., McKeith, I. G., Thomas, A. J., Pietrini, P., Huey, E. D., Wassermann, E. M., Baborie, A., Jaros, E., Tierney, M. C., Pastor, P., Razquin, C., Ortega-Cubero, S., Alonso, E., Perneczky, R., Diehl-Schmid, J., Alexopoulos, P., Kurz, A., Rainero, I., Rubino, E., Pinessi, L., Rogaeva, E., George-Hyslop, P. S., Rossi, G., Tagliavini, F., Giaccone, G., Rowe, J. B., Schlachetzki, J. C. M., Uphill, J., Collinge, J., Mead, S., Danek, A., Van Deerlin, V. M., Grossman, M., Trojanowski, J. Q., Van Der Zee, J., Cruts, M., Van Broeckhoven, C., Cappa, S. F., Leber, I., Hannequin, D., Golfier, V., Vercelletto, M., Brice, A., Nacmias, B., Sorbi, S., Bagnoli, S., Piaceri, I., Nielsen, J. E., Hjermind, L. E., Riemenschneider, M., Mayhaus, M., Ibach, B., Gasparoni, G., Pichler, S., Gu, W., Rossor, M. N., Fox, N. C., Warren, J. D., Spillantini, M. G., Morris, H. R., Rizzu, P., Heutink, P., Snowden, J. S., Rollinson, S., Richardson, A., Gerhard, A., Bruni, A. C., Maletta, R., Frangipane, F., Cupidi, C., Bernardi, L., Anfossi, M., Gallo, M., Conidi, M. E., Smirne, N., Rademakers, R., Baker, M., Dickson, D. W., Graff-Radford, N. R., Petersen, R. C., Knopman, D., Josephs, K. A., Boeve, B. F., Parisi, J. E., Seeley, W. W., Karydas, A. M., Rosen, H., Van Swieten, J. C., Dopper, E. G. P., Seelaar, H., Pijnenburg, Y. A. L., Scheltens, P., Logroscino, G., Capozzo, R., Novelli, V., Puca, A. A., Franceschi, M., Postiglione, A., Milan, G., Sorrentino, P., Kristiansen, M., Chiang, H-H., Graff, C., Pasquier, F., Rollin, A., Deramecourt, V., Lebouvier, T., Kapogiannis, D., Ferrucci, L., Pickering-Brown, S., Singleton, A. B. & International FTD-Genomics Consortium (IFGC) International Parkinson's Disease Genetics Consortium (IPDGC), I. G. O. A. P. IGAP., 2018, In : Translational Psychiatry. 8, 1

Research output: Contribution to journalArticle

Cytosolic prion protein (PrP) is not toxic in N2a cells and primary neurons expressing pathogenic PrP mutations

Fioriti, L., Dossena, S., Stewart, L. R., Stewart, R. S., Harris, D. A., Forloni, G. & Chiesa, R., Mar 25 2005, In : Journal of Biological Chemistry. 280, 12, p. 11320-11328 9 p.

Research output: Contribution to journalArticle

Decreased [3H]hemicholinium binding to high-affinity choline uptake sites in aged rat brain

Forloni, G. & Angeretti, N., Jan 20 1992, In : Brain Research. 570, 1-2, p. 354-357 4 p.

Research output: Contribution to journalArticle

Decrease in [3H]hemicholinium binding to high-affinity choline uptake sites in deafferented striatum: restoration by oxiracetam

Forloni, G., Angeretti, N., Amoroso, D., Addis, A. & Consolo, S., Oct 15 1990, In : Brain Research. 530, 1, p. 156-160 5 p.

Research output: Contribution to journalArticle

Densitometric Quantification of Neuronal Viability by Computerized Image Analysis

Andreoni, G., Angeretti, N., Lucca, E. & Forloni, G., Nov 1997, In : Experimental Neurology. 148, 1, p. 281-287 7 p.

Research output: Contribution to journalArticle

Deprivation of growth hormone-releasing hormone early in the rat's neonatal life permanently affects somatotropic function

Cella, S. G., Locatelli, V., Mennini, T., Zanini, A., Bendotti, C., Forloni, G. L., Fumagalli, G., Arce, V. M., De Gennaro Colonna, V., Wehrenberg, W. B. & Müller, E. E., Oct 1990, In : Endocrinology. 127, 4, p. 1625-1634 10 p.

Research output: Contribution to journalArticle

Detection of prion seeding activity in the olfactory mucosa of patients with Fatal Familial Insomnia

Redaelli, V., Bistaffa, E., Zanusso, G., Salzano, G., Sacchetto, L., Rossi, M., De Luca, C. M. G., Di Bari, M., Portaleone, S. M., Agrimi, U., Legname, G., Roiter, I., Forloni, G., Tagliavini, F. & Moda, F., Apr 7 2017, In : Scientific Reports. 7, p. 46269

Research output: Contribution to journalArticle