• 6885 Citations
  • 42 h-Index
1988 …2019
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Research Output 1988 2019

  • 6885 Citations
  • 42 h-Index
  • 139 Article
  • 5 Chapter
  • 5 Review article
  • 1 Comment/debate
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Article
2019

The importance of endothelial dysfunction in resistance artery remodelling and cardiovascular risk

Masi, S., Georgiopoulos, G., Chiriacò, M., Grassi, G., Seravalle, G., Savoia, C., Volpe, M., Taddei, S., Rizzoni, D. & Virdis, A., Apr 8 2019, In : Cardiovascular Research.

Research output: Contribution to journalArticle

Arteries
Nitric Oxide
Myography
Hypertension
Pressure
2018
5 Citations (Scopus)

Age- and sex-specific reference values for media/lumen ratio in small arteries and relationship with risk factors

Study Group on Micro- and Macrocirculation of the Italian Society of Hypertension (SIIA), Jan 1 2018, In : Hypertension. 71, 6, p. 1193-1200 8 p.

Research output: Contribution to journalArticle

Reference Values
Arteries
Blood Pressure
Cholesterol
Body Mass Index

Sympathetic and baroreflex abnormalities in the uncomplicated prediabetic state

Dell'Oro, R., Trevano, F. Q., Gamba, P., Ciuffarella, C., Seravalle, G., Mancia, G. & Grassi, G., May 1 2018, In : Journal of Hypertension. 36, 5, p. 1195-1200 6 p.

Research output: Contribution to journalArticle

Prediabetic State
Baroreflex
Adrenergic Agents
Reflex
Disease Progression
2017
2 Citations (Scopus)

Follow-up of Antihypertensive Therapy Improves Blood Pressure Control: Results of HYT (HYperTension survey) Follow-up

Fici, F., Seravalle, G., Koylan, N., Nalbantgil, I., Cagla, N., Korkut, Y., Quarti-Trevano, F., Makel, W. & Grassi, G., Sep 1 2017, In : High Blood Pressure and Cardiovascular Prevention. 24, 3, p. 289-296 8 p.

Research output: Contribution to journalArticle

Antihypertensive Agents
Blood Pressure
Hypertension
Therapeutics
Renin-Angiotensin System

Multicenter Randomized Double-Blind Comparison of Nebivolol plus HCTZ and Irbesartan plus HCTZ in the Treatment of Isolated Systolic Hypertension in Elderly Patients: Results of the NEHIS Study

Grassi, G., Seravalle, G. L., Brambilla, G., Delloro, R., Trevano, F. Q., Fici, F., Van Bortel, L. M. & Mancia, G., 2017, In : Advances in Therapy. p. 1-15 15 p.

Research output: Contribution to journalArticle

irbesartan
Nebivolol
Hydrochlorothiazide
Blood Pressure
Hypertension
3 Citations (Scopus)

Reliability of heart rate as neuroadrenergic marker in the metabolic syndrome

Quarti Trevano, F., Seravalle, G., MacChiarulo, M., Villa, P., Valena, C., Dell'Oro, R., Mancia, G. & Grassi, G., Aug 1 2017, In : Journal of Hypertension. 35, 8, p. 1685-1690 6 p.

Research output: Contribution to journalArticle

Heart Rate
Norepinephrine
Adrenergic Agents
Muscles
Blood Pressure
9 Citations (Scopus)

Restoration of normal sympathetic neural function in heart failure following baroreflex activation therapy: Final 43-month study report

Dell'Oro, R., Gronda, E., Seravalle, G., Costantino, G., Alberti, L., Baronio, B., Staine, T., Vanoli, E., Mancia, G. & Grassi, G., Dec 1 2017, In : Journal of Hypertension. 35, 12, p. 2532-2536 5 p.

Research output: Contribution to journalArticle

Baroreflex
Heart Failure
Hospitalization
Therapeutics
Stroke Volume
2016

Alterations in sympathetic nerve traffic in genetic haemochromatosis before and after iron depletion therapy: A microneurographic study

Seravalle, G. L., Piperno, A., Mariani, R., Pelloni, I., Facchetti, R., Dell'Oro, R., Cuspidi, C., Mancia, G. & Grassi, G., Mar 21 2016, In : European Heart Journal. 37, 12, p. 988-995 8 p.

Research output: Contribution to journalArticle

Hemochromatosis
Iron
Iron Overload
Baroreflex
Therapeutics
2 Citations (Scopus)

Alterations in sympathetic nerve traffic in genetic haemochromatosis before and after iron depletion therapy: A microneurographic study

Seravalle, G., Piperno, A., Mariani, R., Pelloni, I., Facchetti, R., Dell'oro, R., Cuspidi, C., Mancia, G. & Grassi, G., Mar 21 2016, In : European Heart Journal. 37, 12, p. 988-995 8 p.

Research output: Contribution to journalArticle

Hemochromatosis
Iron
Iron Overload
Baroreflex
Therapeutics
7 Citations (Scopus)

Differential effects of enalapril-felodipine versus enalapril-lercanidipine combination drug treatment on sympathetic nerve traffic and metabolic profile in obesity-related hypertension

Seravalle, G., Brambilla, G., Pizzalla, D. P., Casati, A., Riva, M., Cuspidi, C., Bombelli, M., Mancia, G. & Grassi, G., Mar 1 2016, In : Journal of the American Society of Hypertension. 10, 3, p. 244-251 8 p.

Research output: Contribution to journalArticle

Felodipine
Enalapril
Metabolome
Drug Combinations
Obesity

Effects of chronic carotid baroreceptor activation on arterial stiffness in severe heart failure

Gronda, E., Brambilla, G., Seravalle, G. L., Maloberti, A., Cairo, M., Costantino, G., Lovett, E. G., Vanoli, E., Mancia, G. & Grassi, G., Oct 1 2016, In : Clinical Research in Cardiology. 105, 10, p. 838-846 9 p.

Research output: Contribution to journalArticle

Vascular Stiffness
Pressoreceptors
Heart Failure
Baroreflex
Muscles
Sympathetic Nervous System
Obesity
Hypertension
Clinical Studies
2015
4 Citations (Scopus)

Asymmetric and symmetric dimethylarginine and sympathetic nerve traffic after renal denervation in patients with resistant hypertension

Grassi, G., Seravalle, G., Trevano, F. Q., Spaziani, D., Scalise, F., Auguadro, C., Pizzini, P., Tripepi, G., D’Arrigo, G., Mallamaci, F., Mancia, G. & Zoccali, C., Sep 4 2015, In : Clinical Journal of the American Society of Nephrology. 10, 9, p. 1560-1567 8 p.

Research output: Contribution to journalArticle

Denervation
Hypertension
Kidney
Control Groups
Sympathetic Nervous System
27 Citations (Scopus)

Blood Pressure Responses to Renal Denervation Precede and Are Independent of the Sympathetic and Baroreflex Effects

Grassi, G., Seravalle, G., Brambilla, G., Trabattoni, D., Cuspidi, C., Corso, R., Pieruzzi, F., Genovesi, S., Stella, A., Facchetti, R., Spaziani, D., Bartorelli, A. & Mancia, G., Jun 20 2015, In : Hypertension. 65, 6, p. 1209-1216 8 p.

Research output: Contribution to journalArticle

Baroreflex
Denervation
Blood Pressure
Kidney
Muscles
Pressoreceptors
Heart Failure
Hypertension
Carotid Sinus
Health Care Costs
4 Citations (Scopus)

HYT-Hypertension in Turkey: A Cross-Sectional Survey on Blood Pressure Control with Calcium Channel Blockers Alone or Combined with Other Antihypertensive Drugs

Seravalle, G., Koylan, N., Nalbantgil, I., Caglar, N., Quarti-Trevano, F., Makel, W., Grassi, G. & Fici, F., Jun 11 2015, In : High Blood Pressure and Cardiovascular Prevention. 22, 2, p. 165-172 8 p.

Research output: Contribution to journalArticle

Calcium Channel Blockers
Turkey
Antihypertensive Agents
Cross-Sectional Studies
Blood Pressure
23 Citations (Scopus)

Long-term chronic baroreflex activation: Persistent efficacy in patients with heart failure and reduced ejection fraction

Gronda, E., Seravalle, G., Trevano, F. Q., Costantino, G., Casini, A., Alsheraei, A., Lovett, E. G., Vanoli, E., Mancia, G. & Grassi, G., Aug 11 2015, In : Journal of Hypertension. 33, 8, p. 1704-1708 5 p.

Research output: Contribution to journalArticle

Baroreflex
Heart Failure
Hospitalization
Therapeutics
Muscles
30 Citations (Scopus)

Sympathetic nerve traffic and baroreflex function in optimal, normal, and high-normal blood pressure states

Seravalle, G., Lonati, L., Buzzi, S., Cairo, M., Trevano, F. Q., Dell'Oro, R., Facchetti, R., Mancia, G. & Grassi, G., 2015, In : Journal of Hypertension. 33, 7, p. 1411-1417 7 p.

Research output: Contribution to journalArticle

Baroreflex
Blood Pressure
Hypertension
Blood Group Antigens
Masked Hypertension
9 Citations (Scopus)

Within-visit BP variability, cardiovascular risk factors, and BP control in central and eastern Europe: Findings from the BP-CARE study

Grassi, G., Seravalle, G., Maloberti, A., Facchetti, R., Cuspidi, C., Bombelli, M., Laurent, S., Redon, J. & Mancia, G., 2015, In : Journal of Hypertension. 33, 11, p. 2250-2256 7 p.

Research output: Contribution to journalArticle

Eastern Europe
Blood Pressure
Physical Examination
Cardiovascular Diseases
History
2014
84 Citations (Scopus)

Chronic baroreflex activation effects on sympathetic nerve traffic, baroreflex function, and cardiac haemodynamics in heart failure: A proof-of-concept study

Gronda, E., Seravalle, G., Brambilla, G., Costantino, G., Casini, A., Alsheraei, A., Lovett, E. G., Mancia, G. & Grassi, G., 2014, In : European Journal of Heart Failure. 16, 9, p. 977-983 7 p.

Research output: Contribution to journalArticle

Baroreflex
Heart Failure
Hemodynamics
Therapeutics
Carotid Sinus
23 Citations (Scopus)
Hypertension
Arteries
Microscopic Angioscopy
Laser-Doppler Flowmetry
Arterioles
33 Citations (Scopus)

Long-term sympathoinhibitory effects of surgically induced weight loss in severe obese patients

Seravalle, G., Colombo, M., Perego, P., Giardini, V., Volpe, M., Dell'Oro, R., Mancia, G. & Grassi, G., 2014, In : Hypertension. 64, 2, p. 431-437 7 p.

Research output: Contribution to journalArticle

Gastrectomy
Insulin Resistance
Weight Loss
Bariatric Surgery
Baroreflex
48 Citations (Scopus)

Marked sympathetic activation and baroreflex dysfunction in true resistant hypertension

Grassi, G., Seravalle, G., Brambilla, G., Pini, C., Alimento, M., Facchetti, R., Spaziani, D., Cuspidi, C. & Mancia, G., Dec 20 2014, In : International Journal of Cardiology. 177, 3, p. 1020-1025 6 p.

Research output: Contribution to journalArticle

Baroreflex
Hypertension
Adrenergic Agents
Hemodynamics
Blood Pressure
14 Citations (Scopus)

Regional differences in sympathetic activation in lean and obese normotensive individuals with obstructive sleep apnoea

Grassi, G., Seravalle, G., Brambilla, G., Buzzi, S., Volpe, M., Cesana, F., Dell'Oro, R. & Mancia, G., Feb 2014, In : Journal of Hypertension. 32, 2, p. 383-388 6 p.

Research output: Contribution to journalArticle

Obstructive Sleep Apnea
Skin
Muscles
Sleep Apnea Syndromes
Blood Vessels
14 Citations (Scopus)
Sympathetic Nervous System
Cardiac Arrhythmias
Cardiovascular Diseases
Heart Failure
Obesity
4 Citations (Scopus)

Similarities and differences between renal sympathetic denervation and carotid baroreceptor stimulation

Grassi, G., Seravalle, G., Brambilla, G., Cesana, F., Giannattasio, C. & Mancia, G., 2014, In : Current Vascular Pharmacology. 12, 1, p. 63-68 6 p.

Research output: Contribution to journalArticle

Pressoreceptors
Sympathectomy
Blood Pressure
Kidney
Denervation
2013
2 Citations (Scopus)

Differential patterns of regional neuroadrenergic cardiovascular drive in acromegalic disease

Seravalle, G., Carzaniga, C., Sciortino, G., Attanasio, R., Fatti, L. M., Cozzi, R., Montini, M., Vitale, G., Brambilla, G., Cavagnini, F., Mancia, G., Grassi, G. & Scacchi, M., May 2013, In : Clinical and Experimental Pharmacology and Physiology. 40, 5, p. 333-337 5 p.

Research output: Contribution to journalArticle

Leptin
Acromegaly
Hyperprolactinemia
Pituitary Hormones
Cardiomegaly
4 Citations (Scopus)
6 Citations (Scopus)

Home and ambulatory blood pressure in resistant hypertension.

Grassi, G., Facchetti, R., Seravalle, G., Cuspidi, C. & Mancia, G., May 2013, In : EuroIntervention. 9 Suppl R

Research output: Contribution to journalArticle

Blood Pressure
Hypertension
White Coat Hypertension
Therapeutic Uses
Kidney
8 Citations (Scopus)

How to assess sympathetic nervous system activity in clinical practice

Seravalle, G., Dimitriadis, K., Dell'Oro, R. & Grassi, G., 2013, In : Current Clinical Pharmacology. 8, 3, p. 182-188 7 p.

Research output: Contribution to journalArticle

Sympathetic Nervous System
Norepinephrine
Human Activities
10 Citations (Scopus)

Muscle and skin sympathetic nerve traffic during physician and nurse blood pressure measurement

Grassi, G., Seravalle, G., Buzzi, S., Magni, L., Brambilla, G., Quarti-Trevano, F., Dell'Oro, R. & Mancia, G., Jun 2013, In : Journal of Hypertension. 31, 6, p. 1131-1135 5 p.

Research output: Contribution to journalArticle

Nurses
Blood Pressure
Physicians
Muscles
Skin
44 Citations (Scopus)

Prevalence and clinical characteristics of patients with true resistant hypertension in central and Eastern Europe: Data from the BP-CARE study

Brambilla, G., Bombelli, M., Seravalle, G., Cifkova, R., Laurent, S., Narkiewicz, K., Facchetti, R., Redon, J., Mancia, G. & Grassi, G., Oct 2013, In : Journal of Hypertension. 31, 10, p. 2018-2024 7 p.

Research output: Contribution to journalArticle

Eastern Europe
Blood Pressure
Hypertension
Therapeutics
White Coat Hypertension
16 Citations (Scopus)

Role of ambulatory blood pressure monitoring in resistant hypertension

Grassi, G., Bombelli, M., Seravalle, G., Brambilla, G., Dell'Oro, R. & Mancia, G., Jun 2013, In : Current Hypertension Reports. 15, 3, p. 232-237 6 p.

Research output: Contribution to journalArticle

Ambulatory Blood Pressure Monitoring
Blood Pressure
Hypertension
White Coat Hypertension
Therapeutic Uses
7 Citations (Scopus)

Structural alterations of the retinal microcirculation in the "prehypertensive" high-normal blood pressure state

Grassi, G., Buzzi, S., Dell'Oro, R., Mineo, C., Dimitriadis, K., Seravalle, G., Lonati, L. & Cuspidi, C., 2013, In : Current Pharmaceutical Design. 19, 13, p. 2375-2381 7 p.

Research output: Contribution to journalArticle

Microcirculation
Hypertension
Prehypertension
Retinal Vessels
Hemodynamics
2012
5 Citations (Scopus)

Blood pressure control and antihypertensive treatment

Grassi, G., Seravalle, G., Trevano, F. Q., Dell'Oro, R. & Mancia, G., Jul 2012, In : Current Vascular Pharmacology. 10, 4, p. 506-511 6 p.

Research output: Contribution to journalArticle

Antihypertensive Agents
Blood Pressure
Therapeutics
Drug Combinations
Patient Compliance
7 Citations (Scopus)

Decreased adrenergic tone in acromegaly: Evidence from direct recording of muscle sympathetic nerve activity

Seravalle, G., Carzaniga, C., Attanasio, R., Grassi, G., Lonati, L., Facchini, C., Cozzi, R., Fatti, L. M., Montini, M., Vitale, G., Sciortino, G., Damanti, S., Brambilla, G., Cavagnini, F., Mancia, G. & Scacchi, M., Aug 2012, In : Clinical Endocrinology. 77, 2, p. 262-267 6 p.

Research output: Contribution to journalArticle

Acromegaly
Adrenergic Agents
Muscles
Leptin
Cardiomegaly
9 Citations (Scopus)

Novel antihypertensive therapies: Renal sympathetic nerve ablation and carotid baroreceptor stimulation

Grassi, G., Seravalle, G., Brambilla, G., Bombelli, M., Dell'Oro, R., Gronda, E. & Mancia, G., Dec 2012, In : Current Hypertension Reports. 14, 6, p. 567-572 6 p.

Research output: Contribution to journalArticle

Pressoreceptors
Antihypertensive Agents
Hypertension
Kidney
Metabolome
71 Citations (Scopus)
Sympathetic Nervous System
Chronic Renal Insufficiency
Hypertension
Chronic Kidney Failure
Renal Insufficiency
81 Citations (Scopus)

Sympathetic regulation of vascular function in health and disease

Bruno, R. M., Ghiadoni, L., Seravalle, G., Dell'Oro, R., Taddei, S. & Grassi, G., 2012, In : Frontiers in Physiology. 3 JUL, p. 1-15 15 p.

Research output: Contribution to journalArticle

Blood Vessels
Sympathetic Nervous System
Arteries
Healthy Volunteers
Health

The "sympathetic" kidney: Multiples effects of renal sympathetic nerve ablation

Seravalle, G. & Grassi, G., 2012, In : Current Hypertension Reviews. 8, 4, p. 250-255 6 p.

Research output: Contribution to journalArticle

Kidney
Blood Pressure
Denervation
Homeostasis
Hypertension
20 Citations (Scopus)

The Sympathetic Nervous System and New Nonpharmacologic Approaches to Treating Hypertension: A Focus on Renal Denervation

Grassi, G., Seravalle, G., Brambilla, G. & Mancia, G., May 2012, In : Canadian Journal of Cardiology. 28, 3, p. 311-317 7 p.

Research output: Contribution to journalArticle

Sympathetic Nervous System
Denervation
Hypertension
Kidney
Adrenergic Agents
2011
8 Citations (Scopus)

Association between ADRA1A gene and the metabolic syndrome: Candidate genes and functional counterpart in the PAMELA population

Grassi, G., Padmanabhan, S., Menni, C., Seravalle, G., Lee, W. K., Bombelli, M., Brambilla, G., Quarti-Trevano, F., Giannattasio, C., Cesana, G., Dominiczak, A. & Mancia, G., Jun 2011, In : Journal of Hypertension. 29, 6, p. 1121-1127 7 p.

Research output: Contribution to journalArticle

Population
Genes
Single Nucleotide Polymorphism
Alleles
Sympathetic Nervous System
10 Citations (Scopus)

Cardiovascular consequences of poor compliance to antihypertensive therapy

Grassi, G., Seravalle, G. & Mancia, G., Aug 2011, In : Blood Pressure. 20, 4, p. 196-203 8 p.

Research output: Contribution to journalArticle

Angiotensin Receptor Antagonists
Risk Reduction Behavior
Antihypertensive Agents
Clinical Trials
Medication Adherence
50 Citations (Scopus)

Diagnosis and management of patients with white-coat and masked hypertension

Mancia, G., Bombelli, M., Seravalle, G. & Grassi, G., Dec 2011, In : Nature Reviews Cardiology. 8, 12, p. 686-693 8 p.

Research output: Contribution to journalArticle

Masked Hypertension
White Coat Hypertension
Blood Pressure
Life Style
Lipids
186 Citations (Scopus)

Early sympathetic activation in the initial clinical stages of chronic renal failure

Grassi, G., Quarti-Trevano, F., Seravalle, G., Arenare, F., Volpe, M., Furiani, S., Delloro, R. & Mancia, G., Apr 2011, In : Hypertension. 57, 4, p. 846-851 6 p.

Research output: Contribution to journalArticle

Chronic Kidney Failure
Muscles
Peroneal Nerve
Glomerular Filtration Rate
Renal Insufficiency

Il nuovo concetto del trattamento del rischio cardiovascolare totale

Translated title of the contribution: The new concept of total cardiovascular risk managementSeravalle, G., Grassi, G. & Mancia, G., Sep 2011, In : Italian Journal of Medicine. 5, 3, p. 169-174 6 p.

Research output: Contribution to journalArticle

Risk Management
Hypertension
Hypercholesterolemia
Diabetes Mellitus
Cardiovascular Diseases

Sympathetic activation in hypertension and in hypertension-related metabolic disease

Grassi, G., Brambilla, G. & Seravalle, G., Sep 2011, In : Current Hypertension Reviews. 7, 2, p. 60-65 6 p.

Research output: Contribution to journalArticle

Metabolic Diseases
Pharmacology
Hypertension
Hyperinsulinism
Insulin Resistance
38 Citations (Scopus)

Sympathetic mechanisms, organ damage, and antihypertensive treatment

Grassi, G., Seravalle, G., Dell'Oro, R. & Mancia, G., Aug 2011, In : Current Hypertension Reports. 13, 4, p. 303-308 6 p.

Research output: Contribution to journalArticle

Adrenergic Agents
Antihypertensive Agents
Renal Insufficiency
Diastolic Heart Failure
Hypertension
36 Citations (Scopus)

Sympathetic nerve traffic and asymmetric dimethylarginine in chronic kidney disease

Grassi, G., Seravalle, G., Ghiadoni, L., Tripepi, G., Bruno, R. M., Mancia, G. & Zoccali, C., Nov 1 2011, In : Clinical Journal of the American Society of Nephrology. 6, 11, p. 2620-2627 8 p.

Research output: Contribution to journalArticle

Chronic Renal Insufficiency
Proteinuria
Nitric Oxide Synthase
N,N-dimethylarginine
Muscles
2 Citations (Scopus)

Sympathoinhibitory effects of statins in chronic kidney disease: Are they clinically relevant?

Zoccali, C., Seravalle, G. & Grassi, G., Nov 2011, In : Journal of Hypertension. 29, 11, p. 2064-2067 4 p.

Research output: Contribution to journalArticle