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Research Output 1997 2019

2009

Analysis of GNAS1 and PRKAR1A gene mutations in human cardiac myxomas not associated with multiple endocrine disorders.

Mantovani, G., Bondioni, S., Corbetta, S., Menicanti, L., Rubino, B., Peverelli, E., Labarile, P., Dall'Asta, C., Ambrosi, B., Beck-Peccoz, P., Lania, A. G. & Spada, A., Jun 2009, In : Journal of Endocrinological Investigation. 32, 6, p. 501-504 4 p.

Research output: Contribution to journalArticle

Myxoma
Carney Complex
Mutation
Genes
Polyostotic Fibrous Dysplasia
Cell Proliferation
Calcium
Somatostatin
Phosphorylation
Hormones

Protein kinase A regulatory subunits in human adipose tissue: Decreased R2B expression and activity in adipocytes from obese subjects

Mantovani, G., Bondioni, S., Alberti, L., Gilardini, L., Invitti, C., Corbetta, S., Zappa, M. A., Ferrero, S., Lania, A. G., Bosari, S., Beck-Peccoz, P. & Spada, A., Mar 2009, In : Diabetes. 58, 3, p. 620-626 7 p.

Research output: Contribution to journalArticle

Cyclic AMP-Dependent Protein Kinases
Adipocytes
Adipose Tissue
Intra-Abdominal Fat
Lipolysis
2008

Cell-specific regulation of PTX3 by glucocorticoid hormones in hematopoietic and nonhematopoietic cells

Doni, A., Mantovani, G., Porta, C., Tuckermann, J., Reichardt, H. M., Kleiman, A., Sironi, M., Rubino, L., Pasqualini, F., Nebuloni, M., Signorini, S., Peri, G., Sica, A., Beck-Peccoz, P., Bottazzi, B. & Mantovani, A., Oct 31 2008, In : Journal of Biological Chemistry. 283, 44, p. 29983-29992 10 p.

Research output: Contribution to journalArticle

Glucocorticoids
Hormones
Endothelial cells
Fibroblasts
Dendritic Cells

Different expression of protein kinase A (PKA) regulatory subunits in cortisol-secreting adrenocortical tumors: Relationship with cell proliferation

Mantovani, G., Lania, A. G., Bondioni, S., Peverelli, E., Pedroni, C., Ferrero, S., Pellegrini, C., Vicentini, L., Arnaldi, G., Bosari, S., Beck-Peccoz, P. & Spada, A., Jan 1 2008, In : Experimental Cell Research. 314, 1, p. 123-130 8 p.

Research output: Contribution to journalArticle

Cyclic AMP-Dependent Protein Kinases
Hydrocortisone
Cell Proliferation
Carney Complex
Neoplasms

Dopamine D2 receptor gene polymorphisms and response to cabergoline therapy in patients with prolactin-secreting pituitary adenomas

Filopanti, M., Barbieri, A. M., Angioni, A. R., Colao, A., Gasco, V., Grottoli, S., Peri, A., Baglioni, S., Fustini, M. F., Pigliaru, F., Monte, P. D., Borretta, G., Ambrosi, B., Jaffrain-Rea, M. L., Gasperi, M., Brogioni, S., Cannavò, S., Mantovani, G., Beck-Peccoz, P., Lania, A. & 1 others, Spada, A., 2008, In : Pharmacogenomics Journal. 8, 5, p. 357-363 7 p.

Research output: Contribution to journalArticle

Prolactinoma
Dopamine D2 Receptors
Prolactin
Genes
Gene Frequency

Effect of 9-cis retinoic acid on dopamine D2 receptor expression in pituitary adenoma cells

Bondioni, S., Angioni, A. R., Corbetta, S., Locatelli, M., Ferrero, S., Ferrante, E., Mantovani, G., Olgiati, L., Beck-Peccoz, P., Spada, A. & Lania, A. G., Apr 2008, In : Experimental Biology and Medicine. 233, 4, p. 439-446 8 p.

Research output: Contribution to journalArticle

Dopamine D2 Receptors
Pituitary Neoplasms
Growth Hormone
Cells
Retinoids

Genetic abnormalities of somatostatin receptors in pituitary tumors

Lania, A., Mantovani, G. & Spada, A., May 14 2008, In : Molecular and Cellular Endocrinology. 286, 1-2, p. 180-186 7 p.

Research output: Contribution to journalArticle

Somatostatin Receptors
Pituitary Neoplasms
Tumors
Genes
Somatostatin

High expression of PKA regulatory subunit 1A protein is related to proliferation of human melanoma cells

Mantovani, G., Bondioni, S., Lania, A. G., Rodolfo, M., Peverelli, E., Polentarutti, N., Veliz Rodriguez, T., Ferrero, S., Bosari, S., Beck-Peccoz, P. & Spada, A., Mar 20 2008, In : Oncogene. 27, 13, p. 1834-1843 10 p.

Research output: Contribution to journalArticle

Protein Subunits
Cyclic AMP-Dependent Protein Kinases
Melanocytes
Melanoma
Caspase 3

The third intracellular loop of the human somatostatin receptor 5 is crucial for arrestin binding and receptor internalization after somatostatin stimulation

Peverelli, E., Mantovani, G., Calebiro, D., Doni, A., Bondioni, S., Lania, A., Beck-Peccoz, P. & Spada, A., Mar 2008, In : Molecular Endocrinology. 22, 3, p. 676-688 13 p.

Research output: Contribution to journalArticle

Arrestin
Somatostatin
Arrestins
Fluorescence Microscopy
Serine
2007

Evaluation of proopiomelanocortin mRNA in the peripheral blood from patients with Cushing's syndrome of different origin

Bondioni, S., Mantovani, G., Polentarutti, N., Ambrosi, B., Loli, P., Peverelli, E., Lania, A. G., Beck-Peccoz, P. & Spada, A., Nov 2007, In : Journal of Endocrinological Investigation. 30, 10, p. 828-832 5 p.

Research output: Contribution to journalArticle

Pro-Opiomelanocortin
Cushing Syndrome
Adrenocorticotropic Hormone
Messenger RNA
Pituitary ACTH Hypersecretion

Genetic analysis and evaluation of resistance to thyrotropin and growth hormone-releasing hormone in pseudohypoparathyroidism type Ib

Mantovani, G., Bondioni, S., Linglart, A., Maghnie, M., Cisternino, M., Corbetta, S., Lania, A. G., Beck-Peccoz, P. & Spada, A., Sep 2007, In : Journal of Clinical Endocrinology and Metabolism. 92, 9, p. 3738-3742 5 p.

Research output: Contribution to journalArticle

Pseudohypoparathyroidism
Growth Hormone-Releasing Hormone
Thyrotropin
Defects
Methylation

Hormonal signaling and pituitary adenomas

Spada, A., Lania, A. & Mantovani, G., May 2007, In : Neuroendocrinology. 85, 2, p. 101-109 9 p.

Research output: Contribution to journalArticle

Pituitary Neoplasms
Tumor Suppressor Genes
Hormones
Proto-Oncogenes
Growth

Modulation of cyclin D1 expression in human tumoral parathyroid cells: Effects of growth factors and calcium sensing receptor activation

Corbetta, S., Eller-Vainicher, C., Vicentini, L., Lania, A., Mantovani, G., Beck-Peccoz, P. & Spada, A., Sep 18 2007, In : Cancer Letters. 255, 1, p. 34-41 8 p.

Research output: Contribution to journalArticle

Calcium-Sensing Receptors
Cyclin D1
Intercellular Signaling Peptides and Proteins
Transforming Growth Factors
MAP Kinase Signaling System

Patients with macroprolactinaemia: Clinical and radiological features

Donadio, F., Barbieri, A., Angioni, R., Mantovani, G., Beck-Peccoz, P., Spada, A. & Lania, A. G., Jul 2007, In : European Journal of Clinical Investigation. 37, 7, p. 552-557 6 p.

Research output: Contribution to journalArticle

Hyperprolactinemia
Magnetic resonance
Imaging techniques
Prolactin
Magnetic Resonance Imaging
2006

DAX1 and X-linked adrenal hypoplasia congenita: Clinical and molecular analysis in five patients

Mantovani, G., De Menis, E., Borretta, G., Radetti, G., Bondioni, S., Spada, A., Persani, L. & Beck-Peccoz, P., May 2006, In : European Journal of Endocrinology. 154, 5, p. 685-689 5 p.

Research output: Contribution to journalArticle

Mutation
Semen Analysis
Gonadotropins
Rete Testis
Orphan Nuclear Receptors

HESX1 expression in human normal pituitaries and pituitary adenomas

Mantovani, G., Asteria, C., Pellegrini, C., Bosari, S., Alberti, L., Bondioni, S., Peverelli, E., Spada, A. & Beck-Peccoz, P., Mar 9 2006, In : Molecular and Cellular Endocrinology. 247, 1-2, p. 135-139 5 p.

Research output: Contribution to journalArticle

Pituitary Neoplasms
Tumors
Adrenocorticotropic Hormone
Genes
Messenger RNA
Endocrine System Diseases
G-Protein-Coupled Receptors
GTP-Binding Proteins
Mutation
Hormones

Mutations in the Gs alpha gene causing hormone resistance

Mantovani, G. & Spada, A., Dec 2006, In : Best Practice and Research: Clinical Endocrinology and Metabolism. 20, 4, p. 501-513 13 p.

Research output: Contribution to journalArticle

Hormones
Mutation
G-Protein-Coupled Receptors
GTP-Binding Proteins
Cyclic AMP

Octreotide promotes apoptosis in human somatotroph tumor cells by activating somatostatin receptor type 2

Ferrante, E., Pellegrini, C., Bondioni, S., Peverelli, E., Locatelli, M., Gelmini, P., Luciani, P., Peri, A., Mantovani, G., Bosari, S., Beck-Peccoz, P., Spada, A. & Lania, A., Sep 2006, In : Endocrine-Related Cancer. 13, 3, p. 955-962 8 p.

Research output: Contribution to journalArticle

Somatotrophs
Octreotide
Apoptosis
Neoplasms
Somatostatin
Pseudohypoparathyroidism
Growth Hormone-Releasing Hormone
Thyrotropin
Parathyroid Hormone
Gonadotropins
2005

Activity and function of the nuclear factor kappaB pathway in human parathyroid tumors

Corbetta, S., Vicentini, L., Ferrero, S., Lania, A., Mantovani, G., Cordella, D., Beck-Peccoz, P. & Spada, A., Dec 2005, In : Endocrine-Related Cancer. 12, 4, p. 929-937 9 p.

Research output: Contribution to journalArticle

Cyclin D1
Calcium-Sensing Receptors
Neoplasms
Phosphorylation
Tumor Necrosis Factor-alpha

Adiponectin expression in human fetal tissues during mid- and late gestation

Corbetta, S., Bulfamante, G., Cortelazzi, D., Barresi, V., Cetin, I., Mantovani, G., Bondioni, S., Beck-Peccoz, P. & Spada, A., Apr 2005, In : Journal of Clinical Endocrinology and Metabolism. 90, 4, p. 2397-2402 6 p.

Research output: Contribution to journalArticle

Adiponectin
Fetus
Tissue
Pregnancy
Umbilicus

Albright's Hereditary Osteodystrophy (Pseudohypoparathyroidism type Ia): Clinical case with a novel mutation of GNAS1

Garavelli, L., Pedori, S., Zanacca, C., Caselli, G., Loiodice, A., Mantovani, G., Ammenti, A., Virdis, R. & Banchini, G., 2005, In : Acta Biomedica. 76, 1

Research output: Contribution to journalArticle

Pseudohypoparathyroidism
Mutation
Heterotopic Ossification
Metacarpal Bones
Hypocalcemia

Effect of cyclic adenosine 3′,5′-monophosphate/protein kinase A pathway on markers of cell proliferation in nonfunctioning pituitary adenomas

Mantovani, G., Bondioni, S., Ferrero, S., Gamba, B., Ferrante, E., Peverelli, E., Corbetta, S., Locatelli, M., Rampini, P., Beck-Peccoz, P., Spada, A. & Lania, A. G., Dec 2005, In : Journal of Clinical Endocrinology and Metabolism. 90, 12, p. 6721-6724 4 p.

Research output: Contribution to journalArticle

Cell proliferation
Pituitary Neoplasms
Cyclic AMP-Dependent Protein Kinases
Adenosine
Cyclin D1

Expression of the antiapoptotic gene seladin-1 and octreotide-induced apoptosis in growth hormone-secreting and nonfunctioning pituitary adenomas

Luciani, P., Gelmini, S., Ferrante, E., Lania, A., Benvenuti, S., Baglioni, S., Mantovani, G., Cellai, I., Ammannati, F., Spada, A., Serio, M. & Peri, A., Nov 2005, In : Journal of Clinical Endocrinology and Metabolism. 90, 11, p. 6156-6161 6 p.

Research output: Contribution to journalArticle

Growth Hormone-Secreting Pituitary Adenoma
Octreotide
Pituitary Neoplasms
Growth Hormone
Tumors

Expression of the two alternatively spliced PRKAR1A RNAs in human endocrine glands

Peverelli, E., Mantovani, G., Bondioni, S., Pellegrini, C., Bosari, S., Lania, A. G., Beck-Peccoz, P. & Spada, A., Jun 30 2005, In : Molecular and Cellular Endocrinology. 238, 1-2, p. 51-55 5 p.

Research output: Contribution to journalArticle

Endocrine Glands
Carney Complex
RNA
Tissue
Tumors

Inactivating and activating mutations of the Gs alpha gene

Spada, A., Mantovani, G. & Lania, A., Jun 2005, In : Annales d'Endocrinologie. 66, 3, p. 258-263 6 p.

Research output: Contribution to journalArticle

Mutational analysis of PRKAR1A and Gsα in sporadic adrenocortical tumors

Libé, R., Mantovani, G., Bondioni, S., Lania, A. G., Pedroni, C., Beck-Peccoz, P. & Spada, A., May 2005, In : Experimental and Clinical Endocrinology and Diabetes. 113, 5, p. 248-251 4 p.

Research output: Contribution to journalArticle

Mutation
Loss of Heterozygosity
Neoplasms
Oncogenes
Adenoma

Pathogenesis of prolactinomas

Spada, A., Mantovani, G. & Lania, A., Jan 2005, In : Pituitary. 8, 1, p. 7-15 9 p.

Research output: Contribution to journalArticle

Prolactinoma
Neoplasms
Tumor Suppressor Genes
Lactotrophs
Proto-Oncogenes

Somatic mutational analysis of DAX1 in testes from men with idiopathic azoospermia

Mantovani, G., Mancini, M., Gazzano, G., Spada, A., Colpi, G. M., Beck-Peccoz, P. & Persani, L., Nov 2005, In : Fertility and Sterility. 84, 5, p. 1542-1544 3 p.

Research output: Contribution to journalArticle

Azoospermia
Testis
DAX-1 Orphan Nuclear Receptor
Mutation
Orphan Nuclear Receptors
2004

Biallelic expression of the Gsα gene in human bone and adipose tissue

Mantovani, G., Bondioni, S., Locatelli, M., Pedroni, C., Lania, A. G., Ferrante, E., Filopanti, M., Beck-Peccoz, P. & Spada, A., Dec 2004, In : Journal of Clinical Endocrinology and Metabolism. 89, 12, p. 6316-6319 4 p.

Research output: Contribution to journalArticle

Pseudohypoparathyroidism
Adipose Tissue
Bone
Genes
Tissue

Erratum: PTX3 plays a key role in the organization of the cumulus oophrus extracellular matrix and in in vivo fertilization (Development vol. 131 (1577-1586))

Salustri, A., Garlanda, C., Hirsch, E., De Acetis, M., Maccagno, A., Bottazzi, B., Doni, A., Bastone, A., Mantovani, G., Peccoz, P. B., Salvatori, G., Mahoney, D. J., Day, A. J., Siracusa, G., Romani, L. & Mantovani, A., May 2004, In : Development. 131, 9, p. 2235 1 p.

Research output: Contribution to journalArticle

Gonadotropin-releasing hormone initiates multiple signaling pathways in human GH-secreting adenomas

Lania, A., Mantovani, G., Ferrante, E., Zavanone, L. M., Locatelli, M., Corbetta, S., Beck-Peccoz, P. & Spada, A., Apr 2004, In : Journal of Endocrinological Investigation. 27, 4, p. 328-333 6 p.

Research output: Contribution to journalArticle

Gonadotropin-Releasing Hormone
Adenoma
Adenylyl Cyclases
LHRH Receptors
Neoplasms

Parental origin of Gsα mutations in the McCune-Albright syndrome and in isolated endocrine tumors

Mantovani, G., Bondioni, S., Lania, A. G., Corbetta, S., De Sanctis, L., Cappa, M., Di Battista, E., Chanson, P., Beck-Peccoz, P. & Spada, A., Jun 2004, In : Journal of Clinical Endocrinology and Metabolism. 89, 6, p. 3007-3009 3 p.

Research output: Contribution to journalArticle

Polyostotic Fibrous Dysplasia
Poisons
Tumors
Genes
Adenoma

Proliferation of transformed somatotroph cells related to low or absent expression of protein kinase A regulatory subunit 1A protein

Lania, A. G., Mantovani, G., Ferrero, S., Pellegrini, C., Bondioni, S., Peverelli, E., Braidotti, P., Locatelli, M., Zavanone, M. L., Ferrante, E., Bosari, S., Beck-Peccoz, P. & Spada, A., Dec 15 2004, In : Cancer Research. 64, 24, p. 9193-9198 6 p.

Research output: Contribution to journalArticle

Somatotrophs
Protein Subunits
Cyclic AMP-Dependent Protein Kinases
Carney Complex
Mutation

PTX3 plays a key role in the organization of the cumulus oophorus extracellular matrix and in in vivo fertilization

Salustri, A., Garlanda, C., Hirsch, E., De Acetis, M., Maccagno, A., Bottazi, B., Doni, A., Bastone, A., Mantovani, G., Peccoz, P. B., Salvatori, G., Mahoney, D. J., Day, A. J., Siracusa, G., Romani, L. & Mantovani, A., Apr 2004, In : Development. 131, 7, p. 1577-1586 10 p.

Research output: Contribution to journalArticle

Hyaluronic Acid
Fertilization
Extracellular Matrix
Fertility
Cumulus Cells
2003

An alternate translation initiation site circumvents an amino-terminal DAX1 nonsense mutation leading to a mild form of X-linked adrenal hypoplasia congenita

Ozisik, G., Mantovani, G., Achermann, J. C., Persani, L., Spada, A., Weiss, J., Beck-Peccoz, P. & Jameson, J. L., Jan 1 2003, In : Journal of Clinical Endocrinology and Metabolism. 88, 1, p. 417-423 7 p.

Research output: Contribution to journalArticle

Nonsense Codon
Mutation
Proteins
Phenotype
Adrenal Insufficiency

Genetics of pituitary tumors: Focus on G-protein mutations

Lania, A., Mantovani, G. & Spada, A., Oct 2003, In : Experimental Biology and Medicine. 228, 9, p. 1004-1017 14 p.

Research output: Contribution to journalArticle

Pituitary Neoplasms
GTP-Binding Proteins
Tumors
Oncogenes
Mutation

Growth hormone-releasing hormone resistance in pseudohypoparathyroidism type Ia: New evidence for imprinting of the Gsα gene

Mantovani, G., Maghnie, M., Weber, G., De Menis, E., Brunelli, V., Cappa, M., Loli, P., Beck-Peccoz, P. & Spada, A., Sep 1 2003, In : Journal of Clinical Endocrinology and Metabolism. 88, 9, p. 4070-4074 5 p.

Research output: Contribution to journalArticle

Pseudohypoparathyroidism
Growth Hormone-Releasing Hormone
Adrenocorticotropic Hormone
Hydrocortisone
Genes

Isolated follicle-stimulating hormone (FSH) deficiency in a young man with normal virilization who did not have mutations in the FSHβ gene

Mantovani, G., Borgato, S., Beck-Peccoz, P., Romoli, R., Borretta, G. & Persani, L., Feb 1 2003, In : Fertility and Sterility. 79, 2, p. 434-436 3 p.

Research output: Contribution to journalArticle

Virilism
Follicle Stimulating Hormone
Mutation
Genes
Gonadotropin-Releasing Hormone
2002

Hypogonadotropic hypogonadism as a presenting feature of late-onset X-linked adrenal hypoplasia congenita

Mantovani, G., Ozisik, G., Achermann, J. C., Romoli, R., Borretta, G., Persani, L., Spada, A., Larry Jameson, J. & Beck-Peccoz, P., 2002, In : Journal of Clinical Endocrinology and Metabolism. 87, 1, p. 44-48 5 p.

Research output: Contribution to journalArticle

Hypogonadism
DAX-1 Orphan Nuclear Receptor
Gonadotropins
Gene expression
Assays

The Gsα gene: Predominant maternal origin of transcription in human thyroid gland and gonads

Mantovani, G., Ballare, E., Giammona, E., Beck-Peccoz, P. & Spada, A., Oct 1 2002, In : Journal of Clinical Endocrinology and Metabolism. 87, 10, p. 4736-4740 5 p.

Research output: Contribution to journalArticle

Gonads
Transcription
Thyroid Gland
Genes
Alleles
2001

Absence of thyroid transcription factor-1 expression in human parathyroid and pituitary glands

Mantovani, G., Corbetta, S., Romoli, R., Alberti, L., Beck-Peccoz, P. & Spada, A., Aug 20 2001, In : Molecular and Cellular Endocrinology. 182, 1, p. 13-17 5 p.

Research output: Contribution to journalArticle

Parathyroid Glands
Pituitary Gland
Tissue
Calcium-Sensing Receptors
Rats

G protein mutations in endocrine diseases

Lania, A., Mantovani, G. & Spada, A., 2001, In : European Journal of Endocrinology. 145, 5, p. 543-559 17 p.

Research output: Contribution to journalArticle

Endocrine System Diseases
GTP-Binding Proteins
Mutation
Pseudohypoparathyroidism
Adenylyl Cyclases

Relevant cAMP-specific phosphodiesterase isoforms in human pituitary: Effect of Gsα mutations

Persani, L., Borgato, S., Lania, A., Filopanti, M., Mantovani, G., Conti, M. & Spada, A., 2001, In : Journal of Clinical Endocrinology and Metabolism. 86, 8, p. 3795-3800 6 p.

Research output: Contribution to journalArticle

Phosphoric Diester Hydrolases
Type 4 Cyclic Nucleotide Phosphodiesterase
Protein Isoforms
Adenoma
Mutation
Growth Hormone-Secreting Pituitary Adenoma
Somatostatin Receptors
Human Growth Hormone
Somatostatin
Sequence Analysis
2000

Calcium-sensing receptor expression and signalling in human parathyroid adenomas and primary hyperplasia

Corbetta, S., Mantovani, G., Lania, A., Borgato, S., Vicentini, L., Beretta, E., Faglia, G., Di Blasio, A. M. & Spada, A., 2000, In : Clinical Endocrinology. 52, 3, p. 339-348 10 p.

Research output: Contribution to journalArticle

Calcium-Sensing Receptors
Parathyroid Neoplasms
Hyperplasia
Gq-G11 GTP-Binding Protein alpha Subunits
Neoplasms

Induction of specific phosphodiesterase isoforms by constitutive activation of the cAMP pathway in autonomous thyroid adenomas

Persani, L., Lania, A., Alberti, L., Romoli, R., Mantovani, G., Filetti, S., Spada, A. & Conti, M., 2000, In : Journal of Clinical Endocrinology and Metabolism. 85, 8, p. 2872-2878 7 p.

Research output: Contribution to journalArticle

Thyrotropin Receptors
Phosphoric Diester Hydrolases
Thyroid Neoplasms
Protein Isoforms
Chemical activation

Mutational analysis of GNAS1 in patients with pseudohypoparathyroidism: Identification of two novel mutations

Mantovani, G., Romoli, R., Weber, G., Brunelli, V., De Menis, E., Beccio, S., Beck-Peccoz, P. & Spada, A., 2000, In : Journal of Clinical Endocrinology and Metabolism. 85, 11, p. 4243-4248 6 p.

Research output: Contribution to journalArticle

Pseudohypoparathyroidism
Pseudopseudohypoparathyroidism
Exons
Mutation
Genes