If you made any changes in Pure these will be visible here soon.

Research Output 2006 2019

Filter
Article
2006
Sp1 Transcription Factor
Genetic Promoter Regions
Italy
Single Nucleotide Polymorphism
Hypertension
2011

Angiotensin-converting enzyme (ACE) genotypes and disability in hospitalized older patients

Seripa, D., Paroni, G., Matera, M. G., Gravina, C., Scarcelli, C., Corritore, M., D'Ambrosio, L. P., Urbano, M., D'Onofrio, G., Copetti, M., Kehoe, P. G., Panza, F. & Pilotto, A., Sep 2011, In : Age. 33, 3, p. 409-419 11 p.

Research output: Contribution to journalArticle

Peptidyl-Dipeptidase A
Activities of Daily Living
Genotype
Genetic Markers
Logistic Models

Effectiveness of a high-throughput genetic analysis in the identification of responders/non-responders to CYP2D6-metabolized drugs

Savino, M., Seripa, D., Gallo, A. P., Garrubba, M., D'Onofrio, G., Bizzarro, A., Paroni, G., Paris, F., Mecocci, P., Masullo, C., Pilotto, A. & Santini, S. A., 2011, In : Clinical Laboratory. 57, 11-12, p. 887-893 7 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP2D6
Throughput
Pharmaceutical Preparations
Alleles
Polymorphism

Effect of obesity, serum lipoproteins, and apolipoprotein e genotypes on mortality in hospitalized elderly patients

Addante, F., Sancarlo, D., Copetti, M., Scarcelli, C., Longo, M. G., Niro, V., Paroni, G., Pellegrini, F., Fontana, L. & Pilotto, A., Apr 1 2011, In : Rejuvenation Research. 14, 2, p. 111-118 8 p.

Research output: Contribution to journalArticle

Apolipoproteins
Apolipoproteins E
Lipoproteins
Body Mass Index
Obesity
2012

Advances in the identification of γ-secretase inhibitors for the treatment of Alzheimer's disease

D'Onofrio, G., Panza, F., Frisardi, V., Solfrizzi, V., Imbimbo, B. P., Paroni, G., Cascavilla, L., Seripa, D. & Pilotto, A., Jan 2012, In : Expert Opinion on Drug Discovery. 7, 1, p. 19-37 19 p.

Research output: Contribution to journalArticle

Amyloid Precursor Protein Secretases
Alzheimer Disease
Amyloid beta-Protein Precursor
Amyloid
N2-((2S)-2-(3,5-difluorophenyl)-2-hydroxyethanoyl)-N1-((7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-L-alaninamide

Forkhead-box-O1 locus y marcadores metabólicos en los ancianos: Estudio de asociación

Translated title of the contribution: Forkhead-box-O1 locus and metabolic markers in the elderly: An association studyParoni, G., Addante, F., Seripa, D., Panza, F., Copetti, M., Fontana, L. & Pilotto, A., Nov 2012, In : Revista Espanola de Geriatria y Gerontologia. 47, 6, p. 254-258 5 p.

Research output: Contribution to journalArticle

Genetic Models
Single Nucleotide Polymorphism
Analysis of Variance
Glucose
Fasting

Klotho locus, metabolic traits, and serum hemoglobin in hospitalized older patients: A genetic association analysis

Paroni, G., Seripa, D., Panza, F., Addante, F., Copetti, M., D'Onofrio, G., Pellegrini, F., Fontana, L. & Pilotto, A., Aug 2012, In : Age. 34, 4, p. 949-968 20 p.

Research output: Contribution to journalArticle

Fasting
Hemoglobins
HDL Cholesterol
Serum
Lymphocyte Count

Pharmacogenetics in older people: What we know and what we need to know

Seripa, D., Paroni, G., Urbano, M., Santini, S. A., D'Onofrio, G. & Pilotto, A., 2012, In : Journal of Nephrology. 25, SUPPL.19

Research output: Contribution to journalArticle

Pharmacogenetics
Drug-Related Side Effects and Adverse Reactions
Pharmaceutical Preparations
Therapeutics
Proteins

The serotonin transporter gene locus in late-life major depressive disorder

Seripa, D., Panza, F., D'Onofrio, G., Paroni, G., Bizzarro, A., Fontana, A., Paris, F., Cascavilla, L., Copetti, M., Masullo, C. & Pilotto, A., Jan 31 2012, (Accepted/In press) In : American Journal of Geriatric Psychiatry.

Research output: Contribution to journalArticle

Serotonin Plasma Membrane Transport Proteins
Major Depressive Disorder
Genes
Haplotypes
Neurotransmitter Transport Proteins

Usefulness of the multidimensional prognostic index (MPI) in the management of older patients with chronic kidney disease

Pilotto, A., Panza, F., Sancarlo, D., Paroni, G., Maggi, S. & Ferrucci, L., 2012, In : Journal of Nephrology. 25, SUPPL.19

Research output: Contribution to journalArticle

Chronic Renal Insufficiency
Mortality
Geriatric Assessment
Institutionalization
Pressure Ulcer
2013

Development and Validation of a Multidimensional Prognostic Index for Mortality Based on a Standardized Multidimensional Assessment Schedule (MPI-SVaMA) in Community-Dwelling Older Subjects

Pilotto, A., Gallina, P., Fontana, A., Sancarlo, D., Bazzano, S., Copetti, M., Maggi, S., Paroni, G., Marcato, F., Pellegrini, F., Donato, D. & Ferrucci, L., Apr 2013, In : Journal of the American Medical Directors Association. 14, 4, p. 287-292 6 p.

Research output: Contribution to journalArticle

Independent Living
Appointments and Schedules
Mortality
Activities of Daily Living
Nursing Care

Identification of a metabolic signature for multidimensional impairment and mortality risk in hospitalized older patients

Fontana, L., Addante, F., Copetti, M., Paroni, G., Fontana, A., Sancarlo, D., Pellegrini, F., Ferrucci, L. & Pilotto, A., Jun 2013, In : Aging Cell. 12, 3, p. 459-466 8 p.

Research output: Contribution to journalArticle

Mortality
Insulin-Like Growth Factor I
Biomarkers
Inflammation
Geriatric Assessment

The serotonin transporter gene locus in late-life major depressive disorder

Seripa, D., Panza, F., D'Onofrio, G., Paroni, G., Bizzarro, A., Fontana, A., Paris, F., Cascavilla, L., Copetti, M., Masullo, C. & Pilotto, A., Jan 2013, In : American Journal of Geriatric Psychiatry. 21, 1, p. 67-77 11 p.

Research output: Contribution to journalArticle

Serotonin Plasma Membrane Transport Proteins
Major Depressive Disorder
Genes
Haplotypes
Neurotransmitter Transport Proteins
2014

An association study between epicardial fat thickness and cognitive impairment in the elderly

Mazzoccoli, G., Dagostino, M. P., Vinciguerra, M., Ciccone, F., Paroni, G., Seripa, D., Addante, F., Montella, R. C., De Cosmo, S., Sera, F. & Greco, A., Nov 1 2014, In : American Journal of Physiology - Heart and Circulatory Physiology. 307, 9, p. H1269-H1276

Research output: Contribution to journalArticle

Adipose Tissue
Fats
Intra-Abdominal Fat
Cognition
Echocardiography

Effects of hypercapnia on peripheral vascular reactivity in elderly patients with acute exacerbation of chronic obstructive pulmonary disease

de Matthaeis, A., Greco, A., Dagostino, M. P., Paroni, G., Fontana, A., Vinciguerra, M., Mazzoccoli, G., Seripa, D. & Vendemiale, G., May 29 2014, In : Clinical Interventions in Aging. 9, p. 871-878 8 p.

Research output: Contribution to journalArticle

Hypercapnia
Chronic Obstructive Pulmonary Disease
Blood Vessels
Dilatation
Vasodilation

FOXO1 locus and acetylcholinesterase inhibitors in elderly patients with Alzheimer’s disease

Paroni, G., Seripa, D., Fontana, A., D’Onofrio, G., Gravina, C., Urbano, M., Cascavilla, L., Pellegrini, F., Greco, A. & Pilotto, A., 2014, In : Clinical Interventions in Aging. 9, p. 1783-1791 9 p.

Research output: Contribution to journalArticle

Cholinesterase Inhibitors
Alzheimer Disease
Rivastigmine
Genotype
Haplotypes

Frailty, disability and physical exercise in the aging process and in chronic kidney disease

Greco, A., Paroni, G., Seripa, D., Addante, F., Dagostino, M. P. & Aucella, F., Apr 18 2014, In : Kidney and Blood Pressure Research. 39, p. 164-168 5 p.

Research output: Contribution to journalArticle

Chronic Renal Insufficiency
Exercise
Sarcopenia
Frail Elderly
Health Status
2015

Measuring pharmacogenetics in special groups: Geriatrics

Seripa, D., Panza, F., Daragjati, J., Paroni, G. & Pilotto, A., Jul 1 2015, In : Expert Opinion on Drug Metabolism and Toxicology. 11, 7, p. 1073-1088 16 p.

Research output: Contribution to journalArticle

Geriatrics
Pharmacogenetics
Cytochrome P-450 Enzyme System
Pharmaceutical Preparations
DNA Methylation

Role of the serotonin transporter gene locus in the response to SSRI treatment of major depressive disorder in late life

Seripa, D., Pilotto, A., Paroni, G., Fontana, A., D'Onofrio, G., Gravina, C., Urbano, M., Cascavilla, L., Paris, F., Panza, F., Padovani, A. & Pilotto, A., May 5 2015, In : Journal of Psychopharmacology. 29, 5, p. 623-633 11 p.

Research output: Contribution to journalArticle

Serotonin Plasma Membrane Transport Proteins
Major Depressive Disorder
Serotonin Uptake Inhibitors
Genes
Serotonin
2016

Brain Atrophy, Anti-Smooth Muscle Antibody and Cognitive Impairment: An Association Study

Paroni, G., Michele, L., Fontana, A., Grazia, DO., Filomena, C., Francesco, P., Leandro, C., Maria, U., Gravina, C., Copetti, M. & Greco, A., Aug 2016, In : Aging and Disease. 7, 4, p. 318-25 8 p.

Research output: Contribution to journalArticle

Atrophy
Smooth Muscle
Antibodies
Brain
Apolipoproteins E

Delusions in patients with Alzheimer's disease: A multidimensional approach

D'Onofrio, G., Panza, F., Sancarlo, D., Paris, F. F., Cascavilla, L., Mangiacotti, A., Lauriola, M., Paroni, G. H., Seripa, D. & Greco, A., Mar 15 2016, In : Journal of Alzheimer's Disease. 51, 2, p. 427-437 11 p.

Research output: Contribution to journalArticle

Delusions
Alzheimer Disease
Depression
Geriatric Assessment
Dementia

Klotho Gene and Selective Serotonin Reuptake Inhibitors: Response to Treatment in Late-Life Major Depressive Disorder

Paroni, G., Seripa, D., Fontana, A., D’Onofrio, G., Gravina, C., Urbano, M., Addante, F., Lozupone, M., Copetti, M., Pilotto, A., Greco, A. & Panza, F., Feb 3 2016, (Accepted/In press) In : Molecular Neurobiology. p. 1-12 12 p.

Research output: Contribution to journalArticle

Major Depressive Disorder
Serotonin Uptake Inhibitors
Genes
Serotonergic Neurons
Delayed Diagnosis
2017
Homeostasis
Fats
Glucose
Genes
Single Nucleotide Polymorphism

Role of CLU, PICALM, and TNK1 Genotypes in Aging With and Without Alzheimer’s Disease

Seripa, D., Panza, F., Paroni, G., D’Onofrio, G., Bisceglia, P., Gravina, C., Urbano, M., Lozupone, M., Solfrizzi, V., Bizzarro, A., Boccardi, V., Piccininni, C., Daniele, A., Logroscino, G., Mecocci, P., Masullo, C. & Greco, A., Jun 19 2017, (Accepted/In press) In : Molecular Neurobiology. p. 1-12 12 p.

Research output: Contribution to journalArticle

Clusterin
Alzheimer Disease
Genotype
Alleles
Single Nucleotide Polymorphism

Role of the APOE polymorphism in carotid and lower limb revascularization: A prospective study from Southern Italy

Mastroianno, S., Di Stolfo, G., Seripa, D., Antonio Pacilli, M., Paroni, G., Coli, C., Urbano, M., D'Arienzo, C., Gravina, C., Rosario Potenza, D., De Luca, G., Greco, A. & Russo, A., Mar 1 2017, In : PLoS One. 12, 3, e0171055.

Research output: Contribution to journalArticle

apolipoprotein E
Apolipoproteins E
prospective studies
Polymorphism
Italy
2018

Erythrocyte associated amyloid-β as potential biomarker to diagnose dementia

Lauriola, M., Paroni, G., Ciccone, F., D’Onofrio, G., Cascavilla, L., Paris, F., Gravina, C., Urbano, M., Seripa, D. & Greco, A., Jan 1 2018, In : Current Alzheimer Research. 15, 4, p. 381-385 5 p.

Research output: Contribution to journalArticle

Amyloid
Dementia
Erythrocytes
Biomarkers
Alzheimer Disease

Klotho at the Edge of Alzheimer’s Disease and Senile Depression

Paroni, G., Panza, F., de Cosmo, S., Greco, A., Seripa, D. & Mazzoccoli, G., Jul 5 2018, (Accepted/In press) In : Molecular Neurobiology. p. 1-13 13 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Depression
Serotonergic Neurons
Poisons
Amyloid

Late-life depression versus amnestic mild cognitive impairment: Alzheimer's disease incidence in 4 years of follow-up

Lauriola, M., Mangiacotti, A., D'Onofrio, G., Cascavilla, L., Paris, F., Ciccone, F., Greco, M., Paroni, G., Seripa, D. & Greco, A., Nov 1 2018, In : Dementia and Geriatric Cognitive Disorders. 46, 3-4, p. 140-153 14 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Depression
Incidence
Antidepressive Agents
Dementia

Neurocognitive disorders and dehydration in older patients: Clinical experience supports the hydromolecular hypothesis of dementia

Lauriola, M., Mangiacotti, A., D’Onofrio, G., Cascavilla, L., Paris, F., Paroni, G., Seripa, D., Greco, A. & Sancarlo, D., May 1 2018, In : Nutrients. 10, 5, 562.

Research output: Contribution to journalArticle

dementia
Dehydration
Dementia
Activities of Daily Living
emotions
2019

Examining the association between genetic liability for schizophrenia and psychotic symptoms in Alzheimer's disease

AddNeuroMed consortium and the Alzheimer’s Disease Neuroimaging Initiative, Oct 22 2019, In : Translational Psychiatry. 9, 1, 1 p.

Research output: Contribution to journalArticle

Schizophrenia
Alzheimer Disease
Delusions
Psychotic Disorders
Empirical Research

Hydroxytryptamine transporter gene-linked polymorphic region (5HTTLPR) is associated with delusions in Alzheimer's disease

D'Onofrio, G., Panza, F., Sancarlo, D., Lauriola, M., Dagostino, M. P., Paroni, G., Lozupone, M., Mangiacotti, A., Bisceglia, P., Gravina, C., Urbano, M., Addante, F., Paris, F., Cascavilla, L., Greco, A. & Seripa, D., Feb 1 2019, In : Translational Neurodegeneration. 8, 1, 4.

Research output: Contribution to journalArticle

Delusions
Serotonin
Alzheimer Disease
Genes
Odds Ratio

Pharmacogenetics in the clinical analysis laboratory: clinical practice, research, and drug development pipeline

Miscio, G., Paroni, G., Bisceglia, P., Gravina, C., Urbano, M., Lozupone, M., Piccininni, C., Prisciandaro, M., Ciavarella, G., Daniele, A., Bellomo, A., Panza, F., Di Mauro, L., Greco, A. & Seripa, D., Sep 1 2019, In : Expert opinion on drug metabolism & toxicology. 15, 9, p. 751-765 15 p.

Research output: Contribution to journalArticle

Clinical laboratories
Pharmacogenetics
Pipelines
Health
Research

Understanding the Amyloid Hypothesis in Alzheimer's Disease

Paroni, G., Bisceglia, P. & Seripa, D., Jan 1 2019, In : Journal of Alzheimer's Disease. 68, 2, p. 493-510 18 p.

Research output: Contribution to journalArticle

Amyloid Plaques
Amyloid
Alzheimer Disease
Apolipoproteins E
Presenilin-2