If you made any changes in Pure these will be visible here soon.

Research Output 1992 2019

2019
Open Access
CXC Chemokines
Chemokine Receptors
DNA Methylation
Hyperglycemia
Stem Cells

Calcium as a key player in arrhythmogenic cardiomyopathy: Adhesion disorder or intracellular alteration?

Moccia, F., Lodola, F., Stadiotti, I., Pilato, C. A., Bellin, M., Carugo, S., Pompilio, G., Sommariva, E. & Maione, A. S., Aug 2 2019, In : International Journal of Molecular Sciences. 20, 16, 3986.

Research output: Contribution to journalReview article

Open Access
mutations
Cardiomyopathies
genes
calcium
Calcium

Cyclophilin a in arrhythmogenic cardiomyopathy cardiac remodeling

Rurali, E., Pilato, C. A., Perrucci, G. L., Scopece, A., Stadiotti, I., Moschetta, D., Casella, M., Cogliati, E., Sommariva, E., Pompilio, G. & Nigro, P., May 2 2019, In : International Journal of Molecular Sciences. 20, 10, 2403.

Research output: Contribution to journalArticle

Open Access
Cyclophilin A
Cyclophilins
Cardiomyopathies
Mesenchymal Stromal Cells
Tissue
Open Access
Induced Pluripotent Stem Cells
Dystrophin
Duchenne Muscular Dystrophy
Exons
Cell Line

Feasibility of planning coronary artery bypass grafting based only on coronary computed tomography angiography and CT-derived fractional flow reserve: a pilot survey of the surgeons involved in the randomized SYNTAX III Revolution trial

Sonck, J., Miyazaki, Y., Collet, C., Onuma, Y., Asano, T., Takahashi, K., Kogame, N., Katagiri, Y., Modolo, R., Serruys, P. W., Bartorelli, A. L., Andreini, D., Doenst, T., Maureira, J. P., Plass, A., La Meir, M. & Pompilio, G., Mar 18 2019, In : Interactive Cardiovascular and Thoracic Surgery.

Research output: Contribution to journalArticle

Coronary Artery Bypass
Coronary Artery Disease
Decision Making
Percutaneous Coronary Intervention
Therapeutics

G-CSF for Extensive STEMI: Results from the STEM-AMI OUTCOME CMR Substudy

Achilli, F., Pontone, G., Bassetti, B., Squadroni, L., Campodonico, J., Corrada, E., Facchini, C., Mircoli, L., Esposito, G., Scarpa, D., Pidello, S., Righetti, S., Di Gennaro, F., Guglielmo, M., Muscogiuri, G., Baggiano, A., Limido, A., Lenatti, L., Di Tano, G., Malafronte, C. & 5 others, Soffici, F., Ceseri, M., Maggiolini, S., Colombo, G. I. & Pompilio, G., May 29 2019, In : Circulation Research.

Research output: Contribution to journalArticle

Scanning Transmission Electron Microscopy
Granulocyte Colony-Stimulating Factor
Magnetic Resonance Spectroscopy
Standard of Care
Ventricular Remodeling

G-CSF for Extensive STEMI: Results from the STEM-AMI OUTCOME CMR Substudy

Achilli, F., Pontone, G., Bassetti, B., Squadroni, L., Campodonico, J., Corrada, E., Facchini, C., Mircoli, L., Esposito, G., Scarpa, D., Pidello, S., Righetti, S., Di Gennaro, F., Guglielmo, M., Muscogiuri, G., Baggiano, A., Limido, A., Lenatti, L., Di Tano, G., Malafronte, C. & 5 others, Soffici, F., Ceseri, M., Maggiolini, S., Colombo, G. & Pompilio, G., 2019, In : Circulation Research. 125, 3, p. 295-306 12 p.

Research output: Contribution to journalArticle

G-CSF for Extensive STEMI: Results from the STEM-AMI OUTCOME CMR Substudy: Circulation Research

STEM-AMI OUTCOME CMR Sub-Study Investigators, Achilli, F., Pontone, G., Bassetti, B., Squadroni, L., Campodonico, J., Corrada, E., Facchini, C., Mircoli, L., Esposito, G., Scarpa, D., Pidello, S., Righetti, S., Di Gennaro, F., Guglielmo, M., Muscogiuri, G., Baggiano, A., Limido, A., Lenatti, L., Di Tano, G. & 6 others, Malafronte, C., Soffici, F., Ceseri, M., Maggiolini, S., Colombo, G. I. & Pompilio, G., 2019, In : Circ. Res.. 125, 3, p. 295-306 12 p.

Research output: Contribution to journalArticle

Coronary Angiography
Coronary Artery Bypass
Transplants
Coronary Vessels
Heart Rate
Oxidative Stress
Endothelial Cells
Aortic Valve Stenosis
MicroRNAs
Aortic Valve

Plasmatic and chamber-specific modulation of cardiac microRNAs in an acute model of DOX-induced cardiotoxicity

Gioffré, S., Ricci, V., Vavassori, C., Ruggeri, C., Chiesa, M., Alfieri, I., Zorzan, S., Buzzetti, M., Milano, G., Scopece, A., Castiglioni, L., Sironi, L., Pompilio, G., Colombo, G. I. & D'Alessandra, Y., Feb 1 2019, In : Biomedicine and Pharmacotherapy. 110, p. 1-8 8 p.

Research output: Contribution to journalArticle

MicroRNAs
Doxorubicin
Computational Biology
Cardiotoxicity
Pharmaceutical Preparations
Open Access
Nitric Oxide Synthase Type III
Response Elements
DNA Methylation
Gene expression regulation
Cardiovascular system

Soluble EMMPRIN levels discriminate aortic ectasia in marfan syndrome patients

Rurali, E., Perrucci, G. L., Gaetano, R., Pini, A., Moschetta, D., Gentilini, D., Nigro, P. & Pompilio, G., 2019, In : Theranostics. 9, 8, p. 2224-2234 11 p.

Research output: Contribution to journalArticle

Soluble EMMPRIN levels discriminate aortic ectasia in marfan syndrome patients

Rurali, E., Perrucci, G. L., Gaetano, R., Pini, A., Moschetta, D., Gentilini, D., Nigro, P. & Pompilio, G., Jan 1 2019, In : Theranostics. 9, 8, p. 2224-2234 11 p.

Research output: Contribution to journalArticle

Open Access
Pathologic Dilatations
Marfan Syndrome
Metalloproteases
Thorax
ROC Curve

The SYNTAX score on its way out or … towards artificial intelligence: part II

Serruys, P. W., Chichareon, P., Modolo, R., Leaman, D. M., Reiber, J. H. C., Emanuelsson, H., Di Mario, C., Pijls, N. H. J., Morel, M-A., Valgimigli, M., Farooq, V., van Klaveren, D., Capodanno, D., Andreini, D., Bourantas, C. V., Davies, J., Banning, A. P., Escaned, J., Piek, J. J., Echavarría-Pinto, M. & 9 others, Taylor, C. A., Thomsen, B., Collet, C., Pompilio, G., Bartorelli, A. L., Glocker, B., Dressler, O., Stone, G. W. & Onuma, Y., Oct 25 2019, In : EuroIntervention.

Research output: Contribution to journalArticle

The SYNTAX score on its way out or … towards artificial intelligence: part I

Serruys, P. W., Chichareon, P., Modolo, R., Leaman, D. M., Reiber, J. H. C., Emanuelsson, H., Di Mario, C., Pijls, N. H. J., Morel, M-A., Valgimigli, M., Farooq, V., van Klaveren, D., Capodanno, D., Andreini, D., Bourantas, C. V., Davies, J., Banning, A. P., Escaned, J., Piek, J. J., Echavarría-Pinto, M. & 9 others, Taylor, C. A., Thomsen, B., Collet, C., Pompilio, G., Bartorelli, A. L., Glocker, B., Dressler, O., Stone, G. W. & Onuma, Y., Oct 25 2019, In : EuroIntervention.

Research output: Contribution to journalArticle

Open Access
Induced Pluripotent Stem Cells
Cardiac Myocytes
Integrins
Cell Differentiation
Biocompatible Materials
2018

Arrhythmogenic cardiomyopathy: what blood can reveal?

Stadiotti, I., Pompilio, G., Maione, A. S., Pilato, C. A., D'Alessandra, Y. & Sommariva, E., Jan 1 2018, (Accepted/In press) In : Heart Rhythm.

Research output: Contribution to journalArticle

Cardiomyopathies
Information Storage and Retrieval
MicroRNAs
Disease Progression
Biomarkers

Cardiac fibrosis in regenerative medicine: destroy to rebuild

Perrucci, G. L., Rurali, E. & Pompilio, G., Jul 2018, In : Journal of Thoracic Disease. 10, Suppl 20, p. S2376-S2389

Research output: Contribution to journalReview article

Regenerative Medicine
Fibrosis
Myocardial Infarction
Thrombospondins
Disintegrins

Cell therapy for heart disease after 15 years: Unmet expectations

Nigro, P., Bassetti, B., Cavallotti, L., Catto, V., Carbucicchio, C. & Pompilio, G., Jan 2018, In : Pharmacological Research. 127, p. 77-91 15 p.

Research output: Contribution to journalReview article

Cell- and Tissue-Based Therapy
Heart Diseases
Clinical Trials
Regenerative Medicine
Patient Selection

Coronary computed tomography angiography for heart team decision-making in multivessel coronary artery disease

SYNTAX III REVOLUTION investigators, Nov 1 2018, In : European Heart Journal. 39, 41, p. 3689-3698 10 p.

Research output: Contribution to journalArticle

Coronary Artery Disease
Decision Making
Angiography
Coronary Artery Bypass
Percutaneous Coronary Intervention

Derivation of human induced pluripotent stem cell line EURACi004-A from skin fibroblasts of a patient with Arrhythmogenic Cardiomyopathy carrying the heterozygous PKP2 mutation c.2569_3018del50

Ermon, B., Volpato, C. B., Cattelan, G., Silipigni, R., Di Segni, M., Cantaloni, C., Casella, M., Pramstaller, P. P., Pompilio, G., Sommariva, E., Meraviglia, V. & Rossini, A., Oct 2018, In : Stem Cell Research. 32, p. 78-82 5 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Cardiomyopathies
Fibroblasts
Cell Line
Skin
Dystrophin
Precision Medicine
Molecular Evolution
Cardiomyopathies
Muscular Dystrophies
Dystrophin
Duchenne Muscular Dystrophy
Cardiac Myocytes
Fibrosis
Inbred mdx Mouse
Induced Pluripotent Stem Cells
Dystrophin
Duchenne Muscular Dystrophy
Exons
Genes

Generation of induced pluripotent stem cells from a Becker muscular dystrophy patient carrying a deletion of exons 45-55 of the dystrophin gene (CCMi002BMD-A-9 ∆45-55)

Gowran, A., Spaltro, G., Casalnuovo, F., Vigorelli, V., Spinelli, P., Castiglioni, E., Rovina, D., Paganini, S., Di Segni, M., Gervasini, C., Nigro, P. & Pompilio, G., Apr 1 2018, In : Stem Cell Research. 28, p. 21-24 4 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Dystrophin
Duchenne Muscular Dystrophy
Exons
Genes
Rubinstein-Taybi Syndrome
Induced Pluripotent Stem Cells
Exons
Cell Line
Mutation
Rubinstein-Taybi Syndrome
Induced Pluripotent Stem Cells
Exons
Cell Line
Mutation

Hdac inhibition improves the sarcoendoplasmic reticulum Ca2+-ATPase activity in cardiac myocytes

Meraviglia, V., Bocchi, L., Sacchetto, R., Florio, M. C., Motta, B. M., Corti, C., Weichenberger, C. X., Savi, M., D’Elia, Y., Rosato-Siri, M. D., Suffredini, S., Piubelli, C., Pompilio, G., Pramstaller, P. P., Domingues, F. S., Stilli, D. & Rossini, A., Feb 1 2018, In : International Journal of Molecular Sciences. 19, 2, 419.

Research output: Contribution to journalArticle

acetylation
muscle cells
Acetylation
Reticulum
Calcium-Transporting ATPases
Inbred SHR Rats
Fibroblasts
Integrins
Rats
Myofibroblasts

Integrin ανβ5 in vitro inhibition limits pro-fibrotic response in cardiac fibroblasts of spontaneously hypertensive rats

Perrucci, G. L., Barbagallo, V. A., Corlianò, M., Tosi, D., Santoro, R., Nigro, P., Poggio, P., Bulfamante, G., Lombardi, F. & Pompilio, G., Dec 12 2018, In : Journal of Translational Medicine. 16, 1, 352.

Research output: Contribution to journalArticle

Inbred SHR Rats
Fibroblasts
Integrins
Rats
Myofibroblasts
Biopsy
Mesenchymal Stromal Cells
Cardiomyopathies
Osteoblasts
Collagenases

miR-34a Promotes Vascular Smooth Muscle Cell Calcification by Downregulating SIRT1 (Sirtuin 1) and Axl (AXL Receptor Tyrosine Kinase)

Badi, I., Mancinelli, L., Polizzotto, A., Ferri, D., Zeni, F., Burba, I., Milano, G., Brambilla, F., Saccu, C., Bianchi, M. E., Pompilio, G., Capogrossi, M. C. & Raucci, A., Sep 2018, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 38, 9, p. 2079-2090 12 p.

Research output: Contribution to journalArticle

Sirtuin 1
Vascular Calcification
Vascular Smooth Muscle
Smooth Muscle Myocytes
Down-Regulation

Phase-contrast microtomography: are the tracers necessary for stem cell tracking in infarcted hearts?

Giuliani, A., Mencarelli, M., Frati, C., Savi, M., Lagrasta, C., Pompilio, G., Rossini, A. & Quaini, F., Jan 1 2018, In : Biomedical Physics and Engineering Express. 4, 5, 055008.

Research output: Contribution to journalArticle

Cell Tracking
Stem Cells
X-Ray Microtomography
Myocardium
Rhodamines

Precise Therapy for Thoracic Aortic Aneurysm in Marfan Syndrome: A Puzzle Nearing Its Solution

Rurali, E., Perrucci, G. L., Pilato, C. A., Pini, A., Gaetano, R., Nigro, P. & Pompilio, G., Sep 1 2018, In : Progress in Cardiovascular Diseases. 61, 3-4, p. 328-335 8 p.

Research output: Contribution to journalReview article

Thoracic Aortic Aneurysm
Marfan Syndrome
Induced Pluripotent Stem Cells
Pharmacogenetics
Dissection

Preferential myofibroblast differentiation of cardiac mesenchymal progenitor cells in the presence of atrial fibrillation

Gambini, E., Perrucci, G. L., Bassetti, B., Spaltro, G., Campostrini, G., Lionetti, M. C., Pilozzi, A., Martinelli, F., Faruggia, A., DiFrancesco, D., Barbuti, A. & Pompilio, G., Feb 2018, In : Translational Research. 192, p. 54-67 14 p.

Research output: Contribution to journalArticle

Myofibroblasts
Mesenchymal Stromal Cells
Atrial Fibrillation
Transforming Growth Factors
Muscle

The arrhythmogenic cardiomyopathy-specific coding and non-coding transcriptome in human cardiac stromal cells

Rainer, J., Meraviglia, V., Blankenburg, H., Piubelli, C., Pramstaller, P. P., Paolin, A., Cogliati, E., Pompilio, G., Sommariva, E., Domingues, F. S. & Rossini, A., Jun 25 2018, In : BMC Genomics. 19, 1, p. 491

Research output: Contribution to journalArticle

Stromal Cells
Cardiomyopathies
Transcriptome
MicroRNAs
Cell Adhesion
2017

Age-dependent increase of oxidative stress regulates microRNA-29 family preserving cardiac health

Heid, J., Cencioni, C., Ripa, R., Baumgart, M., Atlante, S., Milano, G., Scopece, A., Kuenne, C., Guenther, S., Azzimato, V., Farsetti, A., Rossi, G., Braun, T., Pompilio, G., Martelli, F., Zeiher, A. M., Cellerino, A., Gaetano, C. & Spallotta, F., Dec 4 2017, In : Scientific Reports. 7, 1, p. 16839

Research output: Contribution to journalArticle

MicroRNAs
Oxidative Stress
Cytosine
Health
Up-Regulation

Age-dependent increase of oxidative stress regulates microRNA-29 family preserving cardiac health

Heid, J., Cencioni, C., Ripa, R., Baumgart, M., Atlante, S., Milano, G., Scopece, A., Kuenne, C., Guenther, S., Azzimato, V., Farsetti, A., Rossi, G., Braun, T., Pompilio, G., Martelli, F., Zeiher, A. M., Cellerino, A., Gaetano, C. & Spallotta, F., Dec 1 2017, In : Scientific Reports. 7, 1, 16839.

Research output: Contribution to journalArticle

MicroRNAs
Oxidative Stress
Cytosine
Health
Up-Regulation
Adipogenesis
Cardiomyopathies
Sudden Death
Adipose Tissue
Cardiac Arrhythmias

Cell models of arrhythmogenic cardiomyopathy: Advances and opportunities

Sommariva, E., Stadiotti, I., Perrucci, G. L., Tondo, C. & Pompilio, G., Jul 1 2017, In : DMM Disease Models and Mechanisms. 10, 7, p. 823-835 13 p.

Research output: Contribution to journalReview article

Cardiomyopathies
Therapeutic Human Experimentation
Inborn Genetic Diseases
Cell signaling
Rare Diseases

Cell Therapy for Refractory Angina: A Reappraisal

Bassetti, B., Nigro, P., Catto, V., Cavallotti, L., Righetti, S., Achilli, F., Scacciatella, P., Carbucicchio, C. & Pompilio, G., 2017, In : Stem Cells International. 2017, p. 5648690

Research output: Contribution to journalReview article

Cell- and Tissue-Based Therapy
Meta-Analysis
Therapeutics
Cell Count
Biomarkers

Derivation of the Duchenne muscular dystrophy patient-derived induced pluripotent stem cell line lacking DMD exons 49 and 50 (CCMi001DMD-A-3, ∆49, ∆50)

Spaltro, G., Vigorelli, V., Casalnuovo, F., Spinelli, P., Castiglioni, E., Rovina, D., Paganini, S., Di Segni, M., Nigro, P., Gervasini, C., Pompilio, G. & Gowran, A., Dec 2017, In : Stem Cell Research. 25, p. 128-131 4 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Duchenne Muscular Dystrophy
Exons
Cell Line
Dystrophin

Derivation of the Duchenne muscular dystrophy patient-derived induced pluripotent stem cell line lacking DMD exons 49 and 50 (CCMi001DMD-A-3, ∆ 49, ∆ 50)

Spaltro, G., Vigorelli, V., Casalnuovo, F., Spinelli, P., Castiglioni, E., Rovina, D., Paganini, S., Di Segni, M., Nigro, P., Gervasini, C., Pompilio, G. & Gowran, A., Dec 1 2017, In : Stem Cell Research. 25, p. 128-131 4 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Duchenne Muscular Dystrophy
Exons
Cell Line
Dystrophin

Doxorubicin upregulates CXCR4 via miR-200c/ZEB1-dependent mechanism in human cardiac mesenchymal progenitor cells

Beji, S., Milano, G., Scopece, A., Cicchillitti, L., Cencioni, C., Picozza, M., D'Alessandra, Y., Pizzolato, S., Bertolotti, M., Spaltro, G., Raucci, A., Piaggio, G., Pompilio, G., Capogrossi, M. C., Avitabile, D., Magenta, A. & Gambini, E., Aug 24 2017, In : Cell Death and Disease. 8, 8, p. e3020

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Doxorubicin
Up-Regulation
Zinc Finger E-box-Binding Homeobox 1
Cardiomyopathies