• 765 Citations
  • 14 h-Index
20022019
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Research Output 2002 2019

  • 765 Citations
  • 14 h-Index
  • 30 Article
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Article
2019

Macrophages fine tune satellite cell fate in dystrophic skeletal muscle of mdx mice

Madaro, L., Torcinaro, A., De Bardi, M., Contino, F. F., Pelizzola, M., Diaferia, G. R., Imeneo, G., Bouchè, M., Puri, P. L. & De Santa, F., Oct 1 2019, In : PLoS Genetics. 15, 10, p. e1008408

Research output: Contribution to journalArticle

Open Access
Inbred mdx Mouse
skeletal muscle
Skeletal Muscle
muscle
macrophages
2018
4 Citations (Scopus)

Co-optation of Tandem DNA Repeats for the Maintenance of Mesenchymal Identity

Balestrieri, C., Alfarano, G., Milan, M., Tosi, V., Prosperini, E., Nicoli, P., Palamidessi, A., Scita, G., Diaferia, G. R. & Natoli, G., May 17 2018, In : Cell. 173, 5, p. 1150-1164.e14

Research output: Contribution to journalArticle

Tandem Repeat Sequences
Genes
Maintenance
DNA
Nucleotide Motifs
1 Citation (Scopus)

Sustained activation of detoxification pathways promotes liver carcinogenesis in response to chronic bile acid-mediated damage

Collino, A., Termanini, A., Nicoli, P., Diaferia, G., Polletti, S., Recordati, C., Castiglioni, V., Caruso, D., Mitro, N., Natoli, G. & Ghisletti, S., May 1 2018, In : PLoS Genetics. 14, 5, e1007380.

Research output: Contribution to journalArticle

bile acids
detoxification
Bile Acids and Salts
carcinogenesis
cancer
1 Citation (Scopus)

Zc3h10 is a novel mitochondrial regulator

Audano, M., Pedretti, S., Cermenati, G., Brioschi, E., Diaferia, G. R., Ghisletti, S., Cuomo, A., Bonaldi, T., Salerno, F., Mora, M., Grigore, L., Garlaschelli, K., Baragetti, A., Bonacina, F., Catapano, A. L., Norata, G. D., Crestani, M., Caruso, D., Saez, E., De Fabiani, E. & 1 others, Mitro, N., Apr 1 2018, In : EMBO Reports. 19, 4, e45531.

Research output: Contribution to journalArticle

Myoblasts
Electron Transport
Mitochondria
Zinc Fingers
Skeletal Muscle Fibers

Zc3h10 is a novel mitochondrial regulator

Audano, M., Pedretti, S., Cermenati, G., Brioschi, E., Diaferia, G. R., Ghisletti, S., Cuomo, A., Bonaldi, T., Salerno, F., Mora, M., Grigore, L., Garlaschelli, K., Baragetti, A., Bonacina, F., Catapano, A. L., Norata, G. D., Crestani, M., Caruso, D., Saez, E., De Fabiani, E. & 1 others, Mitro, N., 2018, In : EMBO Reports. 19, 4

Research output: Contribution to journalArticle

Myoblasts
Electron Transport
Mitochondria
Zinc Fingers
Skeletal Muscle Fibers

Zc3h10 is a novel mitochondrial regulator

Audano, M., Pedretti, S., Cermenati, G., Brioschi, E., Diaferia, G. R., Ghisletti, S., Cuomo, A., Bonaldi, T., Salerno, F., Mora, M., Grigore, L., Garlaschelli, K., Baragetti, A., Bonacina, F., Catapano, A. L., Norata, G. D., Crestani, M., Caruso, D., Saez, E., De Fabiani, E. & 1 others, Mitro, N., Apr 1 2018, In : EMBO Reports. 19, 4

Research output: Contribution to journalArticle

Myoblasts
Electron Transport
Mitochondria
Zinc Fingers
Skeletal Muscle Fibers
2017
5 Citations (Scopus)

αE-Catenin Is a Positive Regulator of Pancreatic Islet Cell Lineage Differentiation

Jimenez-Caliani, A. J., Pillich, R., Yang, W., Diaferia, G. R., Meda, P., Crisa, L. & Cirulli, V., Aug 8 2017, In : Cell Reports. 20, 6, p. 1295-1306 12 p.

Research output: Contribution to journalArticle

Catenins
Cell Lineage
Islets of Langerhans
Cell Differentiation
Adherens Junctions
2016
34 Citations (Scopus)

Dissection of transcriptional and cis-regulatory control of differentiation in human pancreatic cancer

Diaferia, G. R., Balestrieri, C., Prosperini, E., Nicoli, P., Spaggiari, P., Zerbi, A. & Natoli, G., 2016, (Accepted/In press) In : EMBO Journal.

Research output: Contribution to journalArticle

Dissection
Pancreatic Neoplasms
Adenocarcinoma
Cells
Gene expression

Dissection of transcriptional and cis-regulatory control of differentiation in human pancreatic cancer

Diaferia, G. R., Balestrieri, C., Prosperini, E., Nicoli, P., Spaggiari, P., Zerbi, A. & Natoli, G., 2016, (Accepted/In press) In : EMBO Journal.

Research output: Contribution to journalArticle

Dissection
Pancreatic Neoplasms
Adenocarcinoma
Cells
Gene expression

In Vivo Genetic Screens of Patient-Derived Tumors Revealed Unexpected Frailty of the Transformed Phenotype

Bossi, D., Cicalese, A., Dellino, G. I., Luzi, L., Riva, L., D'Alesio, C., Diaferia, G. R., Carugo, A., Cavallaro, E., Piccioni, R., Barberis, M., Mazzarol, G., Testori, A., Punzi, S., Pallavicini, I., Tosti, G., Giacó, L., Melloni, G. E. M., Heffernan, T. P., Natoli, G. & 4 others, Draetta, G. F., Minucci, S., Pelicci, P. G. & Lanfrancone, L., Jun 2016, In : Cancer Discovery. 6, 6, p. 650-63 14 p.

Research output: Contribution to journalArticle

Phenotype
Neoplasms
Genes
Neoplasm Genes
Growth
2015
38 Citations (Scopus)

Dichotomy of short and long thymic stromal lymphopoietin isoforms in inflammatory disorders of the bowel and skin

Fornasa, G., Tsilingiri, K., Caprioli, F., Botti, F., Mapelli, M., Meller, S., Kislat, A., Homey, B., Di Sabatino, A., Sonzogni, A., Viale, G., Diaferia, G., Gori, A., Longhi, R., Penna, G. & Rescigno, M., Aug 1 2015, In : Journal of Allergy and Clinical Immunology. 136, 2, p. 413-422 10 p.

Research output: Contribution to journalArticle

Protein Isoforms
Skin
thymic stromal lymphopoietin
Cytokines
Introduced Species
1 Citation (Scopus)

When antimicrobial peptides hit the wrong target: A novel link between tumour macrophages and cancer stem cells

Diaferia, G. R. & Natoli, G., Dec 1 2015, In : Gut. 64, 12, p. 1841-1842 2 p.

Research output: Contribution to journalArticle

2013
8 Citations (Scopus)

Cell and Tissue Microarray Technologies for Protein and Nucleic Acid Expression Profiling

Cardano, M., Diaferia, G. R., Falavigna, M., Spinelli, C. C., Sessa, F., DeBlasio, P. & Biunno, I., 2013, In : Journal of Histochemistry and Cytochemistry. 61, 2, p. 116-124 9 p.

Research output: Contribution to journalArticle

Protein Array Analysis
Nucleic Acids
Technology
Genetic Epigenesis
Cell Line
5 Citations (Scopus)

SEL1L regulates adhesion, proliferation and secretion of insulin by affecting integrin signaling

Diaferia, G. R., Cirulli, V. & Biunno, I., Nov 20 2013, In : PLoS One. 8, 11, e79458.

Research output: Contribution to journalArticle

insulin secretion
integrins
Integrins
adhesion
Adhesion
35 Citations (Scopus)

β1 integrin is a crucial regulator of pancreatic β-cell expansion

Diaferia, G. R., Jimenez-Caliani, A. J., Ranjitkar, P., Yang, W., Hardiman, G., Rhodes, C. J., Crisa, L. & Cirulli, V., Aug 15 2013, In : Development. 140, 16, p. 3360-3372 13 p.

Research output: Contribution to journalArticle

Integrins
Islets of Langerhans
cdc Genes
Pancreas
Epithelium
2012
10 Citations (Scopus)

Molecular chaperones as therapeutic targets to counteract proteostasis defects

Cattaneo, M., Dominici, R., Cardano, M., Diaferia, G., Rovida, E. & Biunno, I., Mar 2012, In : Journal of Cellular Physiology. 227, 3, p. 1226-1234 9 p.

Research output: Contribution to journalArticle

Molecular Chaperones
Biological systems
Defects
Proteostasis Deficiencies
Health
110 Citations (Scopus)

The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington's disease patients demonstrates mutation related enhanced lysosomal activity

Camnasio, S., Carri, A. D., Lombardo, A., Grad, I., Mariotti, C., Castucci, A., Rozell, B., Riso, P. L., Castiglioni, V., Zuccato, C., Rochon, C., Takashima, Y., Diaferia, G., Biunno, I., Gellera, C., Jaconi, M., Smith, A., Hovatta, O., Naldini, L., Di Donato, S. & 2 others, Feki, A. & Cattaneo, E., Apr 2012, In : Neurobiology of Disease. 46, 1, p. 41-51 11 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Huntington Disease
Cell Line
Mutation
Genotype
6 Citations (Scopus)

The science of stem cell biobanking: Investing in the future

Diaferia, G. R., Cardano, M., Cattaneo, M., Spinelli, C. C., Dessì, S. S., Deblasio, P. & Biunno, I., Jan 2012, In : Journal of Cellular Physiology. 227, 1, p. 14-19 6 p.

Research output: Contribution to journalArticle

Stem cells
Stem Cells
Cell Count
Drug Discovery
Toxicology
2011
2 Citations (Scopus)

Comprehensive outsourcing biobanking facility to serve the international research community

Diaferia, G. R., Biunno, I. & Deblasio, P., Jun 1 2011, In : Biopreservation and Biobanking. 9, 2, p. 191-194 4 p.

Research output: Contribution to journalArticle

Outsourced Services
Outsourcing
Logistics
Research
Organizations
29 Citations (Scopus)

Endothelium-derived Netrin-4 supports pancreatic epithelial cell adhesion and differentiation through integrins α2β1 and α3β1

Yebra, M., Diaferia, G. R., Montgomery, A. M. P., Kaido, T., Brunken, W. J., Koch, M., Hardiman, G., Crisa, L. & Cirulli, V., 2011, In : PLoS One. 6, 7, e22750.

Research output: Contribution to journalArticle

Cell adhesion
integrins
endothelium
cell adhesion
Cell Adhesion
16 Citations (Scopus)

mSEL-1L (suppressor/enhancer Lin12-like) protein levels influence murine neural stem cell self-renewal and lineage commitment

Cardano, M., Diaferia, G. R., Cattaneo, M., Dessì, S. S., Long, Q., Conti, L., DeBlasio, P., Cattaneo, E. & Biunno, I., May 27 2011, In : Journal of Biological Chemistry. 286, 21, p. 18708-18719 12 p.

Research output: Contribution to journalArticle

Neural Stem Cells
Stem cells
Proteins
Endoplasmic Reticulum-Associated Degradation
Multipotent Stem Cells
15 Citations (Scopus)

Systematic chromosomal analysis of cultured mouse neural stem cell lines

Diaferia, G. R., Conti, L., Redaelli, S., Cattaneo, M., Mutti, C., Deblasio, P., Dalprà, L., Cattaneo, E. & Biunno, I., Aug 1 2011, In : Stem Cells and Development. 20, 8, p. 1411-1423 13 p.

Research output: Contribution to journalArticle

Neural Stem Cells
Cell Line
Embryonic Stem Cells
Chromosome Aberrations
Chromosomal Instability
2010
46 Citations (Scopus)

Deficiency of suppressor enhancer Lin12 1 like (SEL1L) in mice leads to systemic endoplasmic reticulum stress and embryonic lethality

Francisco, A. B., Singh, R., Li, S., Vani, A. K., Yang, L., Munroe, R. J., Diaferia, G., Cardano, M., Biunno, I., Qi, L., Schimenti, J. C. & Long, Q., Apr 30 2010, In : Journal of Biological Chemistry. 285, 18, p. 13694-13703 10 p.

Research output: Contribution to journalArticle

Endoplasmic Reticulum Stress
Endoplasmic Reticulum
Embryonic Structures
Quality Control
Proteins
2009
80 Citations (Scopus)

Cx36 makes channels coupling human pancreatic β-cells, and correlates with insulin expression

Serre-Beinier, V., Bosco, D., Zulianello, L., Charollais, A., Caille, D., Charpantier, E., Gauthier, B. R., Diaferia, G. R., Giepmans, B. N., Lupi, R., Marchetti, P., Deng, S., Buhler, L., Berney, T., Cirulli, V. & Meda, P., 2009, In : Human Molecular Genetics. 18, 3, p. 428-439 12 p.

Research output: Contribution to journalArticle

Insulin
Connexins
Gap Junctions
Proteins
Islets of Langerhans
2008
14 Citations (Scopus)

Is stem cell chromosomes stability affected by cryopreservation conditions?

Diaferia, G. R., Dessì, S. S., DeBlasio, P. & Biunno, I., Sep 2008, In : Cytotechnology. 58, 1, p. 11-16 6 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Switching-on survival and repair response programs in islet transplants by bone marrow-derived vasculogenic cells

Miller, R., Cirulli, V., Diaferia, G. R., Ninniri, S., Hardiman, G., Torbett, B. E., Benezra, R. & Crisa, L., Sep 2008, In : Diabetes. 57, 9, p. 2402-2412 11 p.

Research output: Contribution to journalArticle

Bone Marrow
Transplants
Blood Vessels
Transplantation
Cell Transplantation
2006
79 Citations (Scopus)

Impact of defined matrix interactions on insulin production by cultured human β-cells: Effect on insulin content, secretion, and gene transcription

Kaido, T., Yebra, M., Cirulli, V., Rhodes, C., Diaferia, G. & Montgomery, A. M., Oct 2006, In : Diabetes. 55, 10, p. 2723-2729 7 p.

Research output: Contribution to journalArticle

Cultured Cells
Insulin
Vitronectin
Genes
Collagen
2004
7 Citations (Scopus)

RNA-mediated interference indicates that SEL1L plays a role in pancreatic β-cell growth

Diaferia, G., Cattaneo, M., Saltini, G., Proverbio, M. C., Monferini, E., Malferrari, G., Albertini, A. & Biunno, I., Aug 2004, In : DNA and Cell Biology. 23, 8, p. 510-518 9 p.

Research output: Contribution to journalArticle

RNA Interference
Growth
Endoplasmic Reticulum-Associated Degradation
Endoplasmic Reticulum Stress
Fungal Proteins
2003
171 Citations (Scopus)

Recognition of the neural chemoattractant netrin-1 by integrins α6β4 and α3β1 regulates epithelial cell adhesion and migration

Yebra, M., Montgomery, A. M. P., Diaferia, G. R., Kaido, T., Silletti, S., Perez, B., Just, M. L., Hildbrand, S., Hurford, R., Florkiewicz, E., Tessier-Lavigne, M. & Cirulli, V., Nov 2003, In : Developmental Cell. 5, 5, p. 695-707 13 p.

Research output: Contribution to journalArticle

Chemotactic Factors
Cell adhesion
Cell Adhesion
Integrins
Cell Movement
2002
31 Citations (Scopus)

High-quality genomic DNA from human whole blood and mononuclear cells

Malferrari, G., Monferini, E., DeBlasio, P., Diaferia, G., Saltini, G., Del Vecchio, E., Rossi-Bernardi, L. & Biunno, I., Dec 1 2002, In : BioTechniques. 33, 6, p. 1228-1230 3 p.

Research output: Contribution to journalArticle