Research Output per year
Research Output 1999 2019
- 1 - 50 out of 66 results
- Publication Year, Title (descending)
2019
Characterization of the novel HLA-DPA1*01:20 allele by sequencing-based typing
Cargou, M., Andreani, M., Testa, G., Guidicelli, G. & Visentin, J., Oct 2019, In : HLA. 94, 4, p. 396-397 2 p.Research output: Contribution to journal › Article
Alleles
Codon
Exons
Nucleotides
HLA-DPA1 antigen
Identification of the novel HLA-A*01:289 allele in an Italian patient
Galluccio, T., Locatelli, F., Troiano, M., Testa, G. & Andreani, M., Jun 2019, In : HLA. 93, 6, p. 484-485 2 p.Research output: Contribution to journal › Article
HLA-A Antigens
Alleles
Exons
Nucleotides
2018
HOXB7 overexpression in lung cancer is a hallmark of acquired stem-like phenotype
Monterisi, S., Lo Riso, P., Russo, K., Bertalot, G., Vecchi, M., Testa, G., Di Fiore, P. P. & Bianchi, F., Jun 2018, In : Oncogene. 37, 26, p. 3575-3588 14 p.Research output: Contribution to journal › Article
Induced Pluripotent Stem Cells
Lung Neoplasms
Phenotype
Stem Cells
Body Patterning
8
Citations
(Scopus)
HOXB7 overexpression in lung cancer is a hallmark of acquired stem-like phenotype
Monterisi, S., Lo Riso, P., Russo, K., Bertalot, G., Vecchi, M., Testa, G., DI Fiore, P. P. & Bianchi, F., Jun 1 2018, In : Oncogene. 37, 26, p. 3575-3588 14 p.Research output: Contribution to journal › Article
Induced Pluripotent Stem Cells
Lung Neoplasms
Phenotype
Stem Cells
Body Patterning
2
Citations
(Scopus)
KMT2B Is Selectively Required for Neuronal Transdifferentiation, and Its Loss Exposes Dystonia Candidate Genes
Barbagiovanni, G., Germain, P. L., Zech, M., Atashpaz, S., Lo Riso, P., D'Antonio-Chronowska, A., Tenderini, E., Caiazzo, M., Boesch, S., Jech, R., Haslinger, B., Broccoli, V., Stewart, A. F., Winkelmann, J. & Testa, G., Oct 23 2018, In : Cell Reports. 25, 4, p. 988-1001 14 p.Research output: Contribution to journal › Article
Dystonia
Fibroblasts
Genes
Histones
Lysine
11
Citations
(Scopus)
Scrutinizing the EU general data protection regulation
Marelli, L. & Testa, G., May 4 2018, In : Science. 360, 6388, p. 496-498 3 p.Research output: Contribution to journal › Article
6
Citations
(Scopus)
The chromatin basis of neurodevelopmental disorders: Rethinking dysfunction along the molecular and temporal axes
Gabriele, M., Lopez Tobon, A., D'Agostino, G. & Testa, G., Jan 1 2018, (Accepted/In press) In : Progress in Neuro-Psychopharmacology and Biological Psychiatry.Research output: Contribution to journal › Article
Chromatin
Brain
Epigenomics
Causality
Theoretical Models
The guanine nucleotide exchange factor Arhgef7/βPix promotes axon formation upstream of TC10
López Tobón, A., Suresh, M., Jin, J., Vitriolo, A., Pietralla, T., Tedford, K., Bossenz, M., Mahnken, K., Kiefer, F., Testa, G., Fischer, K-D. & Püschel, A. W., Jun 11 2018, In : Scientific Reports. 8, 1, p. 8811Research output: Contribution to journal › Article
Guanine Nucleotide Exchange Factors
Axons
GTP Phosphohydrolases
Neurons
Monomeric GTP-Binding Proteins
2017
2
Citations
(Scopus)
"Having a structuring effect on Europe": The innovative medicines initiative and the construction of the European health bioeconomy
Marelli, L. & Testa, G., Sep 18 2017, Bioeconomies: Life, Technology, and Capital in the 21st Century. Springer International Publishing AG, p. 73-101 29 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
21
Citations
(Scopus)
Systematic proteome and proteostasis profiling in human Trisomy 21 fibroblast cells
Liu, Y., Borel, C., Li, L., Müller, T., Williams, E. G., Germain, P. L., Buljan, M., Sajic, T., Boersema, P. J., Shao, W., Faini, M., Testa, G., Beyer, A., Antonarakis, S. E. & Aebersold, R., Dec 1 2017, In : Nature Communications. 8, 1, 1212.Research output: Contribution to journal › Article
proteome
fibroblasts
Proteome
Fibroblasts
Down Syndrome
12
Citations
(Scopus)
Taming Human Genetic Variability: Transcriptomic Meta-Analysis Guides the Experimental Design and Interpretation of iPSC-Based Disease Modeling
Germain, P. L. & Testa, G., Jun 6 2017, In : Stem Cell Reports. 8, 6, p. 1784-1796 13 p.Research output: Contribution to journal › Article
Induced Pluripotent Stem Cells
Medical Genetics
Stem cells
Design of experiments
Meta-Analysis
3
Citations
(Scopus)
The European politics of animal experimentation: From Victorian Britain to 'stop Vivisection’
Germain, P. L., Chiapperino, L. & Testa, G., Aug 1 2017, In : Studies in History and Philosophy of Science Part C :Studies in History and Philosophy of Biological and Biomedical Sciences. 64, p. 75-87 13 p.Research output: Contribution to journal › Article
Vivisection
Animal Experimentation
Animals
Victorian Britain
Authority
26
Citations
(Scopus)
YY1 Haploinsufficiency Causes an Intellectual Disability Syndrome Featuring Transcriptional and Chromatin Dysfunction
Gabriele, M., Vulto-van Silfhout, A. T., Germain, P. L., Vitriolo, A., Kumar, R., Douglas, E., Haan, E., Kosaki, K., Takenouchi, T., Rauch, A., Steindl, K., Frengen, E., Misceo, D., Pedurupillay, C. R. J., Stromme, P., Rosenfeld, J. A., Shao, Y., Craigen, W. J., Schaaf, C. P., Rodriguez-Buritica, D. & 31 others, , Jun 1 2017, In : American Journal of Human Genetics. 100, 6, p. 907-925 19 p.Research output: Contribution to journal › Article
Yin-Yang
Haploinsufficiency
Intellectual Disability
Chromatin
Sequence Deletion
2016
10
Citations
(Scopus)
Polycomb dysregulation in gliomagenesis targets a Zfp423-dependent differentiation network
Signaroldi, E., Laise, P., Cristofanon, S., Brancaccio, A., Reisoli, E., Atashpaz, S., Terreni, M. R., Doglioni, C., Pruneri, G., Malatesta, P. & Testa, G., Feb 29 2016, In : Nature Communications. 7, 10753.Research output: Contribution to journal › Article
Epigenetic Repression
Gene Regulatory Networks
Epigenomics
Glioma
Dissection
Polycomb dysregulation in gliomagenesis targets a Zfp423-dependent differentiation network
Signaroldi, E., Laise, P., Cristofanon, S., Brancaccio, A., Reisoli, E., Atashpazgargari, S., Terreni, M. R., Doglioni, C., Pruneri, G., Malatesta, P. & Testa, G., Feb 29 2016, In : Nature Communications. 7, 10753.Research output: Contribution to journal › Article
Epigenetic Repression
Gene Regulatory Networks
Epigenomics
Glioma
Dissection
Polycomb dysregulation in gliomagenesis targets a Zfp423-dependent differentiation network
Signaroldi, E., Laise, P., Cristofanon, S., Brancaccio, A., Reisoli, E., Atashpazgargari, S., Terreni, M. R., Doglioni, C., Pruneri, G., Malatesta, P. & Testa, G., Feb 29 2016, In : Nature Communications. 7, 10753.Research output: Contribution to journal › Article
Epigenetic Repression
Gene Regulatory Networks
Epigenomics
Glioma
Dissection
12
Citations
(Scopus)
RNAontheBENCH: Computational and empirical resources for benchmarking RNAseq quantification and differential expression methods
Germain, P. L., Vitriolo, A., Adamo, A., Laise, P., Das, V. & Testa, G., Jun 20 2016, In : Nucleic Acids Research. 44, 11, p. 5054-5067 14 p.Research output: Contribution to journal › Article
RNA Sequence Analysis
Benchmarking
Gene Expression Profiling
Genes
Libraries
41
Citations
(Scopus)
TRIC: An automated alignment strategy for reproducible protein quantification in targeted proteomics
Röst, H. L., Liu, Y., D'Agostino, G., Zanella, M., Navarro, P., Rosenberger, G., Collins, B. C., Gillet, L., Testa, G., Malmström, L. & Aebersold, R., Aug 30 2016, In : Nature Methods. 13, 9, p. 777-783 7 p.Research output: Contribution to journal › Article
Proteomics
Proteins
Throughput
Induced Pluripotent Stem Cells
Liquid chromatography
2015
54
Citations
(Scopus)
7q11.23 dosage-dependent dysregulation in human pluripotent stem cells affects transcriptional programs in disease-relevant lineages
Adamo, A., Atashpaz, S., Germain, P. L., Zanella, M., D'Agostino, G., Albertin, V., Chenoweth, J., Micale, L., Fusco, C., Unger, C., Augello, B., Palumbo, O., Hamilton, B., Carella, M., Donti, E., Pruneri, G., Selicorni, A., Biamino, E., Prontera, P., McKay, R. & 2 others, , Jan 1 2015, In : Nature Genetics. 47, 2, p. 132-141 10 p.Research output: Contribution to journal › Article
Pluripotent Stem Cells
Williams Syndrome
Phenotype
Induced Pluripotent Stem Cells
Medical Genetics
2014
60
Citations
(Scopus)
Activation of Neuronal Gene Expression by the JMJD3 Demethylase Is Required for Postnatal and Adult Brain Neurogenesis
Park, D. H., Hong, S. J., Salinas, R. D., Liu, S. J., Sun, S. W., Sgualdino, J., Testa, G., Matzuk, M., Iwamori, N. & Lim, D. A., 2014, In : Cell Reports. 8, 5, p. 1290-1299 10 p.Research output: Contribution to journal › Article
Neural Stem Cells
Neurogenesis
Stem cells
Gene expression
Lateral Ventricles
9
Citations
(Scopus)
Brief report: Functional MRI of a patient with 7q11.23 duplication syndrome and autism spectrum disorder
Prontera, P., Serino, D., Caldini, B., Scarponi, L., Merla, G., Testa, G., Muti, M., Napolioni, V., Mazzotta, G., Piccirilli, M. & Donti, E., 2014, In : Journal of Autism and Developmental Disorders. 44, 10, p. 2608-2613 6 p.Research output: Contribution to journal › Article
Magnetic Resonance Imaging
Limbic System
Brain
Short-Term Memory
Magnetic Resonance Spectroscopy
Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis(Journal of Clinical Investigation)
Caganova, M., Carrisi, C., Varano, G., Mainoldi, F., Zanardi, F., Germain, P. L., George, L., Alberghini, F., Ferrarini, L., Talukder, A. K., Ponzoni, M., Testa, G., Nojima, T., Doglioni, C., Kitamura, D., Toellner, K. M., Su, I. H. & Casola, S., Apr 1 2014, In : Journal of Clinical Investigation. 124, 4, p. 1869 1 p.Research output: Contribution to journal › Article
35
Citations
(Scopus)
Multiplex parenting: IVG and the generations to come
Palacios-González, C., Harris, J. & Testa, G., 2014, In : Journal of Medical Ethics. 40, 11, p. 752-758 7 p.Research output: Contribution to journal › Article
Parenting
Germ Cells
liberation
remedies
parents
47
Citations
(Scopus)
Polycomb proteins control proliferation and transformation independently of cell cycle checkpoints by regulating DNA replication
Piunti, A., Rossi, A., Cerutti, A., Albert, M., Jammula, S., Scelfo, A., Cedrone, L., Fragola, G., Olsson, L., Koseki, H., Testa, G., Casola, S., Helin, K., Di Fagagna, F. D. A. & Pasini, D., Apr 14 2014, In : Nature Communications. 5, 3649.Research output: Contribution to journal › Article
Cell Cycle Checkpoints
DNA Replication
Tumors
forks
deoxyribonucleic acid
73
Citations
(Scopus)
Scrutinizing the epigenetics revolution
Meloni, M. & Testa, G., Nov 11 2014, In : BioSocieties. 9, 4, p. 431-456 26 p.Research output: Contribution to journal › Article
Epigenomics
life sciences
discourse
social studies
epistemology
2013
40
Citations
(Scopus)
Cell Reprogramming Requires Silencing of a Core Subset of Polycomb Targets
Fragola, G., Germain, P. L., Laise, P., Cuomo, A., Blasimme, A., Gross, F., Signaroldi, E., Bucci, G., Sommer, C., Pruneri, G., Mazzarol, G., Bonaldi, T., Mostoslavsky, G., Casola, S. & Testa, G., Feb 2013, In : PLoS Genetics. 9, 2, e1003292.Research output: Contribution to journal › Article
Induced Pluripotent Stem Cells
stem
Transcription Factors
transcription factors
cells
37
Citations
(Scopus)
DNA damage in mammalian neural stem cells leads to astrocytic differentiation mediated by BMP2 signaling through JAK-STAT
Schneider, L., Pellegatta, S., Favaro, R., Pisati, F., Roncaglia, P., Testa, G., Nicolis, S. K., Finocchiaro, G. & D'Adda Di Fagagna, F., 2013, In : Stem Cell Reports. 1, 2, p. 123-138 16 p.Research output: Contribution to journal › Article
Neural Stem Cells
Stem cells
DNA Damage
DNA
Adult Stem Cells
109
Citations
(Scopus)
Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis
Caganova, M., Carrisi, C., Varano, G., Mainoldi, F., Zanardi, F., Germain, P. L., George, L., Alberghini, F., Ferrarini, L., Talukder, A. K., Ponzoni, M., Testa, G., Nojima, T., Doglioni, C., Kitamura, D., Toellner, K. M., Su, I. H. & Casola, S., Dec 2 2013, In : Journal of Clinical Investigation. 123, 12, p. 5009-5022 14 p.Research output: Contribution to journal › Article
Germinal Center
B-Lymphocytes
Non-Hodgkin's Lymphoma
Antibody Affinity
Enhancer of Zeste Homolog 2 Protein
6
Citations
(Scopus)
Position statement on the provision and procurement of human eggs for stem cell research
Haimes, E., Skene, L., Ballantyne, A. J., Caulfield, T., Goldstein, L. S., Hyun, I., Kimmelman, J., Robert, J. S., Roxland, B. E., Scott, C. T., Solbakk, J. H., Sugarman, J., Taylor, P. L. & Testa, G., Mar 7 2013, In : Cell Stem Cell. 12, 3, p. 285-291 7 p.Research output: Contribution to journal › Article
Stem Cell Research
Eggs
Oocytes
Research
3
Citations
(Scopus)
Reprogramming Potentiality: The Co-Production of Stem Cell Policy and Democracy
Blasimme, A., Schmietow, B. & Testa, G., Jan 2013, In : American Journal of Bioethics. 13, 1, p. 30-32 3 p.Research output: Contribution to journal › Article
2012
16
Citations
(Scopus)
Consuming genomes: Scientific and social innovation in direct-to-consumer genetic testing
Curnutte, M. & Testa, G., Jun 1 2012, In : New Genetics and Society. 31, 2, p. 159-181 23 p.Research output: Contribution to journal › Article
Genetic Testing
Genome
Genetic Services
innovation
Clinical Medicine
52
Citations
(Scopus)
The H3K27 Demethylase JMJD3 Is Required for Maintenance of the Embryonic Respiratory Neuronal Network, Neonatal Breathing, and Survival
Burgold, T., Voituron, N., Caganova, M., Tripathi, P. P., Menuet, C., Tusi, B. K., Spreafico, F., Bévengut, M., Gestreau, C., Buontempo, S., Simeone, A., Kruidenier, L., Natoli, G., Casola, S., Hilaire, G. & Testa, G., Nov 29 2012, In : Cell Reports. 2, 5, p. 1244-1258 15 p.Research output: Contribution to journal › Article
Pacemakers
Neurogenesis
Methyltransferases
Histones
Lysine
49
Citations
(Scopus)
The Histone Methyltransferase Wbp7 Controls Macrophage Function through GPI Glycolipid Anchor Synthesis
Austenaa, L., Barozzi, I., Chronowska, A., Termanini, A., Ostuni, R., Prosperini, E., Stewart, A. F., Testa, G. & Natoli, G., Apr 20 2012, In : Immunity. 36, 4, p. 572-585 14 p.Research output: Contribution to journal › Article
Glycosylphosphatidylinositols
Glycolipids
Macrophages
Histones
Lipopolysaccharides
14
Citations
(Scopus)
The Identity of Living Beings, Epigenetics, and the Modesty of Philosophy
Boniolo, G. & Testa, G., Mar 2012, In : Erkenntnis. 76, 2, p. 279-298 20 p.Research output: Contribution to journal › Article
Persistence
Phenotype
Molecular Biology
Genome
Continue
2011
106
Citations
(Scopus)
Genomic instability in induced stem cells
Pasi, C. E., Dereli-Öz, A., Negrini, S., Friedli, M., Fragola, G., Lombardo, A., Van Houwe, G., Naldini, L., Casola, S., Testa, G., Trono, D., Pelicci, P. G. & Halazonetis, T. D., May 2011, In : Cell Death and Differentiation. 18, 5, p. 745-753 9 p.Research output: Contribution to journal › Article
Genomic Instability
Stem Cells
DNA Replication
Oncogenes
Breast
9
Citations
(Scopus)
More than just a nucleus: Cloning and the alignment of scientific and political rationalities
Testa, G., 2011, Reframing Rights: Bioconstitutionalism in the Genetic Age. The MIT Press, p. 85-104 20 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
52
Citations
(Scopus)
The Methyltransferase Set7/9 (Setd7) Is Dispensable for the p53-Mediated DNA Damage Response In Vivo
Campaner, S., Spreafico, F., Burgold, T., Doni, M., Rosato, U., Amati, B. & Testa, G., Aug 19 2011, In : Molecular Cell. 43, 4, p. 681-688 8 p.Research output: Contribution to journal › Article
Methyltransferases
DNA Damage
p53 Genes
Acetylation
Apoptosis
19
Citations
(Scopus)
The time of timing: How Polycomb proteins regulate neurogenesis
Testa, G., Jul 2011, In : BioEssays. 33, 7, p. 519-528 10 p.Research output: Contribution to journal › Article
Polycomb-Group Proteins
Gene Targeting
Neurogenesis
Post Translational Protein Processing
Ablation
2010
Stem-cell theatrics
Testa, G., Jun 24 2010, In : Nature. 465, 7301, p. 1012 1 p.Research output: Contribution to journal › Comment/debate
2009
9
Citations
(Scopus)
Ethics Report on Interspecies Somatic Cell Nuclear Transfer Research
Skene, L., Testa, G., Hyun, I., Jung, KW., McNab, A., Robertson, J., Scott, CT., Solbakk, J. H., Taylor, P. & Zoloth, L., Jul 2 2009, In : Cell Stem Cell. 5, 1, p. 27-30 4 p.Research output: Contribution to journal › Article
Ethics
Embryo Transfer
Research
8
Citations
(Scopus)
IL-16 can synergize with early acting cytokines to expand ex vivo CD34 + isolated from cord blood
Rofani, C., Luchetti, L., Testa, G., Lasorella, R., Isacchi, G., Bottazzo, G. F. & Berardi, A. C., May 1 2009, In : Stem Cells and Development. 18, 4, p. 671-682 12 p.Research output: Contribution to journal › Article
Interleukin-16
Fetal Blood
Cytokines
Stem Cells
Thrombopoietin
253
Citations
(Scopus)
Jmjd3 contributes to the control of gene expression in LPS-activated macrophages
De Santa, F., Narang, V., Yap, Z. H., Tusi, B. K., Burgold, T., Austenaa, L., Bucci, G., Caganova, M., Notarbartolo, S., Casola, S., Testa, G., Sung, W. K., Wei, C. L. & Natoli, G., Nov 2009, In : EMBO Journal. 28, 21, p. 3341-3352 12 p.Research output: Contribution to journal › Article
Macrophages
Gene expression
Lipopolysaccharides
Genes
Gene Expression
Nuclear transfer: An example of responsive epistemologies
Testa, G., Dec 2009, In : Current Science. 97, 11, p. 1621-1624 4 p.Research output: Contribution to journal › Article
19
Citations
(Scopus)
The future therapeutic potential of histone demethylases: A critical analysis
Natoli, G., Testa, G. & De Santa, F., Sep 2009, In : Current Opinion in Drug Discovery and Development. 12, 5, p. 607-615 9 p.Research output: Contribution to journal › Article
Histone Demethylases
Histone Code
Histones
Methylation
Drug Delivery Systems
7
Citations
(Scopus)
What to Do with the Grail Now that We Have It? iPSCs, Potentiality, and Public Policy
Testa, G., Oct 2 2009, In : Cell Stem Cell. 5, 4, p. 358-359 2 p.Research output: Contribution to journal › Article
What to Do with the Grail Now that We Have It? iPSCs, Potentiality, and Public Policy (DOI: 10.1016/j.stem.2009.09.007)
Testa, G., Nov 6 2009, In : Cell Stem Cell. 5, 5, p. 567 1 p.Research output: Contribution to journal › Article
2008
13
Citations
(Scopus)
Bacterial artificial chromosome transgenesis through pronuclear injection of fertilized mouse oocytes.
Vintersten, K., Testa, G., Naumann, R., Anastassiadis, K. & Stewart, A. F., 2008, In : Methods in molecular biology (Clifton, N.J.). 415, p. 83-100 18 p.Research output: Contribution to journal › Article
Bacterial Artificial Chromosomes
Gene Transfer Techniques
Oocytes
Injections
Transgenes
115
Citations
(Scopus)
Mast cell-specific Cre/loxP-mediated recombination in vivo
Scholten, J., Hartmann, K., Gerbaulet, A., Krieg, T., Müller, W., Testa, G. & Roers, A., Apr 2008, In : Transgenic Research. 17, 2, p. 307-315 9 p.Research output: Contribution to journal › Article
mast cells
Mast Cells
Genetic Recombination
mice
promoter regions
1
Citation
(Scopus)
Pluripotency and differentiation in embryos and stem cells
Adjaye, J. A., Byskov, A. G., Cibelli, J. B., De Maria, R., Minger, S., Sampaolesia, M., Testa, G., Verfaillie, C., Zernicka-Goetz, M., Schölef, H., Boiani, M., Crosetto, N. & Redi, G. A., 2008, In : International Journal of Developmental Biology. 52, 7, p. 801-809 9 p.Research output: Contribution to journal › Article
141
Citations
(Scopus)
The histone H3 lysine 27-specific demethylase Jmjd3 is required for neural commitment
Burgold, T., Spreafico, F., De Santa, F., Totaro, M. G., Prosperini, E., Natoli, G. & Testa, G., Aug 21 2008, In : PLoS One. 3, 8, e3034.Research output: Contribution to journal › Article
histones
Histones
Lysine
lysine
Neural Stem Cells