• 3333 Citations
  • 26 h-Index
19992019
If you made any changes in Pure these will be visible here soon.

Research Output 1999 2019

  • 3333 Citations
  • 26 h-Index
  • 63 Article
  • 2 Chapter
  • 1 Comment/debate
Filter
Article
2019

Characterization of the novel HLA-DPA1*01:20 allele by sequencing-based typing

Cargou, M., Andreani, M., Testa, G., Guidicelli, G. & Visentin, J., Oct 2019, In : HLA. 94, 4, p. 396-397 2 p.

Research output: Contribution to journalArticle

Alleles
Codon
Exons
Nucleotides
HLA-DPA1 antigen

Identification of the novel HLA-A*01:289 allele in an Italian patient

Galluccio, T., Locatelli, F., Troiano, M., Testa, G. & Andreani, M., Jun 2019, In : HLA. 93, 6, p. 484-485 2 p.

Research output: Contribution to journalArticle

HLA-A Antigens
Alleles
Exons
Nucleotides
2018

HOXB7 overexpression in lung cancer is a hallmark of acquired stem-like phenotype

Monterisi, S., Lo Riso, P., Russo, K., Bertalot, G., Vecchi, M., Testa, G., Di Fiore, P. P. & Bianchi, F., Jun 2018, In : Oncogene. 37, 26, p. 3575-3588 14 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Lung Neoplasms
Phenotype
Stem Cells
Body Patterning
8 Citations (Scopus)

HOXB7 overexpression in lung cancer is a hallmark of acquired stem-like phenotype

Monterisi, S., Lo Riso, P., Russo, K., Bertalot, G., Vecchi, M., Testa, G., DI Fiore, P. P. & Bianchi, F., Jun 1 2018, In : Oncogene. 37, 26, p. 3575-3588 14 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Lung Neoplasms
Phenotype
Stem Cells
Body Patterning
2 Citations (Scopus)

KMT2B Is Selectively Required for Neuronal Transdifferentiation, and Its Loss Exposes Dystonia Candidate Genes

Barbagiovanni, G., Germain, P. L., Zech, M., Atashpaz, S., Lo Riso, P., D'Antonio-Chronowska, A., Tenderini, E., Caiazzo, M., Boesch, S., Jech, R., Haslinger, B., Broccoli, V., Stewart, A. F., Winkelmann, J. & Testa, G., Oct 23 2018, In : Cell Reports. 25, 4, p. 988-1001 14 p.

Research output: Contribution to journalArticle

Dystonia
Fibroblasts
Genes
Histones
Lysine
11 Citations (Scopus)

Scrutinizing the EU general data protection regulation

Marelli, L. & Testa, G., May 4 2018, In : Science. 360, 6388, p. 496-498 3 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
Chromatin
Brain
Epigenomics
Causality
Theoretical Models

The guanine nucleotide exchange factor Arhgef7/βPix promotes axon formation upstream of TC10

López Tobón, A., Suresh, M., Jin, J., Vitriolo, A., Pietralla, T., Tedford, K., Bossenz, M., Mahnken, K., Kiefer, F., Testa, G., Fischer, K-D. & Püschel, A. W., Jun 11 2018, In : Scientific Reports. 8, 1, p. 8811

Research output: Contribution to journalArticle

Guanine Nucleotide Exchange Factors
Axons
GTP Phosphohydrolases
Neurons
Monomeric GTP-Binding Proteins
2017
21 Citations (Scopus)

Systematic proteome and proteostasis profiling in human Trisomy 21 fibroblast cells

Liu, Y., Borel, C., Li, L., Müller, T., Williams, E. G., Germain, P. L., Buljan, M., Sajic, T., Boersema, P. J., Shao, W., Faini, M., Testa, G., Beyer, A., Antonarakis, S. E. & Aebersold, R., Dec 1 2017, In : Nature Communications. 8, 1, 1212.

Research output: Contribution to journalArticle

proteome
fibroblasts
Proteome
Fibroblasts
Down Syndrome
12 Citations (Scopus)
Induced Pluripotent Stem Cells
Medical Genetics
Stem cells
Design of experiments
Meta-Analysis
3 Citations (Scopus)
Vivisection
Animal Experimentation
Animals
Victorian Britain
Authority
26 Citations (Scopus)

YY1 Haploinsufficiency Causes an Intellectual Disability Syndrome Featuring Transcriptional and Chromatin Dysfunction

Gabriele, M., Vulto-van Silfhout, A. T., Germain, P. L., Vitriolo, A., Kumar, R., Douglas, E., Haan, E., Kosaki, K., Takenouchi, T., Rauch, A., Steindl, K., Frengen, E., Misceo, D., Pedurupillay, C. R. J., Stromme, P., Rosenfeld, J. A., Shao, Y., Craigen, W. J., Schaaf, C. P., Rodriguez-Buritica, D. & 31 others, Farach, L., Friedman, J., Thulin, P., McLean, S. D., Nugent, K. M., Morton, J., Nicholl, J., Andrieux, J., Stray-Pedersen, A., Chambon, P., Patrier, S., Lynch, S. A., Kjaergaard, S., Tørring, P. M., Brasch-Andersen, C., Ronan, A., van Haeringen, A., Anderson, P. J., Powis, Z., Brunner, H. G., Pfundt, R., Schuurs-Hoeijmakers, J. H. M., van Bon, B. W. M., Lelieveld, S., Gilissen, C., Nillesen, W. M., Vissers, L. E. L. M., Gecz, J., Koolen, D. A., Testa, G. & de Vries, B. B. A., Jun 1 2017, In : American Journal of Human Genetics. 100, 6, p. 907-925 19 p.

Research output: Contribution to journalArticle

Yin-Yang
Haploinsufficiency
Intellectual Disability
Chromatin
Sequence Deletion
2016
10 Citations (Scopus)

Polycomb dysregulation in gliomagenesis targets a Zfp423-dependent differentiation network

Signaroldi, E., Laise, P., Cristofanon, S., Brancaccio, A., Reisoli, E., Atashpaz, S., Terreni, M. R., Doglioni, C., Pruneri, G., Malatesta, P. & Testa, G., Feb 29 2016, In : Nature Communications. 7, 10753.

Research output: Contribution to journalArticle

Epigenetic Repression
Gene Regulatory Networks
Epigenomics
Glioma
Dissection

Polycomb dysregulation in gliomagenesis targets a Zfp423-dependent differentiation network

Signaroldi, E., Laise, P., Cristofanon, S., Brancaccio, A., Reisoli, E., Atashpazgargari, S., Terreni, M. R., Doglioni, C., Pruneri, G., Malatesta, P. & Testa, G., Feb 29 2016, In : Nature Communications. 7, 10753.

Research output: Contribution to journalArticle

Epigenetic Repression
Gene Regulatory Networks
Epigenomics
Glioma
Dissection

Polycomb dysregulation in gliomagenesis targets a Zfp423-dependent differentiation network

Signaroldi, E., Laise, P., Cristofanon, S., Brancaccio, A., Reisoli, E., Atashpazgargari, S., Terreni, M. R., Doglioni, C., Pruneri, G., Malatesta, P. & Testa, G., Feb 29 2016, In : Nature Communications. 7, 10753.

Research output: Contribution to journalArticle

Epigenetic Repression
Gene Regulatory Networks
Epigenomics
Glioma
Dissection
12 Citations (Scopus)

RNAontheBENCH: Computational and empirical resources for benchmarking RNAseq quantification and differential expression methods

Germain, P. L., Vitriolo, A., Adamo, A., Laise, P., Das, V. & Testa, G., Jun 20 2016, In : Nucleic Acids Research. 44, 11, p. 5054-5067 14 p.

Research output: Contribution to journalArticle

RNA Sequence Analysis
Benchmarking
Gene Expression Profiling
Genes
Libraries
41 Citations (Scopus)

TRIC: An automated alignment strategy for reproducible protein quantification in targeted proteomics

Röst, H. L., Liu, Y., D'Agostino, G., Zanella, M., Navarro, P., Rosenberger, G., Collins, B. C., Gillet, L., Testa, G., Malmström, L. & Aebersold, R., Aug 30 2016, In : Nature Methods. 13, 9, p. 777-783 7 p.

Research output: Contribution to journalArticle

Proteomics
Proteins
Throughput
Induced Pluripotent Stem Cells
Liquid chromatography
2015
54 Citations (Scopus)

7q11.23 dosage-dependent dysregulation in human pluripotent stem cells affects transcriptional programs in disease-relevant lineages

Adamo, A., Atashpaz, S., Germain, P. L., Zanella, M., D'Agostino, G., Albertin, V., Chenoweth, J., Micale, L., Fusco, C., Unger, C., Augello, B., Palumbo, O., Hamilton, B., Carella, M., Donti, E., Pruneri, G., Selicorni, A., Biamino, E., Prontera, P., McKay, R. & 2 others, Merla, G. & Testa, G., Jan 1 2015, In : Nature Genetics. 47, 2, p. 132-141 10 p.

Research output: Contribution to journalArticle

Pluripotent Stem Cells
Williams Syndrome
Phenotype
Induced Pluripotent Stem Cells
Medical Genetics
2014
60 Citations (Scopus)

Activation of Neuronal Gene Expression by the JMJD3 Demethylase Is Required for Postnatal and Adult Brain Neurogenesis

Park, D. H., Hong, S. J., Salinas, R. D., Liu, S. J., Sun, S. W., Sgualdino, J., Testa, G., Matzuk, M., Iwamori, N. & Lim, D. A., 2014, In : Cell Reports. 8, 5, p. 1290-1299 10 p.

Research output: Contribution to journalArticle

Neural Stem Cells
Neurogenesis
Stem cells
Gene expression
Lateral Ventricles
9 Citations (Scopus)

Brief report: Functional MRI of a patient with 7q11.23 duplication syndrome and autism spectrum disorder

Prontera, P., Serino, D., Caldini, B., Scarponi, L., Merla, G., Testa, G., Muti, M., Napolioni, V., Mazzotta, G., Piccirilli, M. & Donti, E., 2014, In : Journal of Autism and Developmental Disorders. 44, 10, p. 2608-2613 6 p.

Research output: Contribution to journalArticle

Magnetic Resonance Imaging
Limbic System
Brain
Short-Term Memory
Magnetic Resonance Spectroscopy

Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis(Journal of Clinical Investigation)

Caganova, M., Carrisi, C., Varano, G., Mainoldi, F., Zanardi, F., Germain, P. L., George, L., Alberghini, F., Ferrarini, L., Talukder, A. K., Ponzoni, M., Testa, G., Nojima, T., Doglioni, C., Kitamura, D., Toellner, K. M., Su, I. H. & Casola, S., Apr 1 2014, In : Journal of Clinical Investigation. 124, 4, p. 1869 1 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Multiplex parenting: IVG and the generations to come

Palacios-González, C., Harris, J. & Testa, G., 2014, In : Journal of Medical Ethics. 40, 11, p. 752-758 7 p.

Research output: Contribution to journalArticle

Parenting
Germ Cells
liberation
remedies
parents
47 Citations (Scopus)

Polycomb proteins control proliferation and transformation independently of cell cycle checkpoints by regulating DNA replication

Piunti, A., Rossi, A., Cerutti, A., Albert, M., Jammula, S., Scelfo, A., Cedrone, L., Fragola, G., Olsson, L., Koseki, H., Testa, G., Casola, S., Helin, K., Di Fagagna, F. D. A. & Pasini, D., Apr 14 2014, In : Nature Communications. 5, 3649.

Research output: Contribution to journalArticle

Cell Cycle Checkpoints
DNA Replication
Tumors
forks
deoxyribonucleic acid
73 Citations (Scopus)

Scrutinizing the epigenetics revolution

Meloni, M. & Testa, G., Nov 11 2014, In : BioSocieties. 9, 4, p. 431-456 26 p.

Research output: Contribution to journalArticle

Epigenomics
life sciences
discourse
social studies
epistemology
2013
40 Citations (Scopus)

Cell Reprogramming Requires Silencing of a Core Subset of Polycomb Targets

Fragola, G., Germain, P. L., Laise, P., Cuomo, A., Blasimme, A., Gross, F., Signaroldi, E., Bucci, G., Sommer, C., Pruneri, G., Mazzarol, G., Bonaldi, T., Mostoslavsky, G., Casola, S. & Testa, G., Feb 2013, In : PLoS Genetics. 9, 2, e1003292.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
stem
Transcription Factors
transcription factors
cells
37 Citations (Scopus)

DNA damage in mammalian neural stem cells leads to astrocytic differentiation mediated by BMP2 signaling through JAK-STAT

Schneider, L., Pellegatta, S., Favaro, R., Pisati, F., Roncaglia, P., Testa, G., Nicolis, S. K., Finocchiaro, G. & D'Adda Di Fagagna, F., 2013, In : Stem Cell Reports. 1, 2, p. 123-138 16 p.

Research output: Contribution to journalArticle

Neural Stem Cells
Stem cells
DNA Damage
DNA
Adult Stem Cells
109 Citations (Scopus)

Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis

Caganova, M., Carrisi, C., Varano, G., Mainoldi, F., Zanardi, F., Germain, P. L., George, L., Alberghini, F., Ferrarini, L., Talukder, A. K., Ponzoni, M., Testa, G., Nojima, T., Doglioni, C., Kitamura, D., Toellner, K. M., Su, I. H. & Casola, S., Dec 2 2013, In : Journal of Clinical Investigation. 123, 12, p. 5009-5022 14 p.

Research output: Contribution to journalArticle

Germinal Center
B-Lymphocytes
Non-Hodgkin's Lymphoma
Antibody Affinity
Enhancer of Zeste Homolog 2 Protein
6 Citations (Scopus)

Position statement on the provision and procurement of human eggs for stem cell research

Haimes, E., Skene, L., Ballantyne, A. J., Caulfield, T., Goldstein, L. S., Hyun, I., Kimmelman, J., Robert, J. S., Roxland, B. E., Scott, C. T., Solbakk, J. H., Sugarman, J., Taylor, P. L. & Testa, G., Mar 7 2013, In : Cell Stem Cell. 12, 3, p. 285-291 7 p.

Research output: Contribution to journalArticle

Stem Cell Research
Eggs
Oocytes
Research
3 Citations (Scopus)

Reprogramming Potentiality: The Co-Production of Stem Cell Policy and Democracy

Blasimme, A., Schmietow, B. & Testa, G., Jan 2013, In : American Journal of Bioethics. 13, 1, p. 30-32 3 p.

Research output: Contribution to journalArticle

2012
16 Citations (Scopus)

Consuming genomes: Scientific and social innovation in direct-to-consumer genetic testing

Curnutte, M. & Testa, G., Jun 1 2012, In : New Genetics and Society. 31, 2, p. 159-181 23 p.

Research output: Contribution to journalArticle

Genetic Testing
Genome
Genetic Services
innovation
Clinical Medicine
52 Citations (Scopus)

The H3K27 Demethylase JMJD3 Is Required for Maintenance of the Embryonic Respiratory Neuronal Network, Neonatal Breathing, and Survival

Burgold, T., Voituron, N., Caganova, M., Tripathi, P. P., Menuet, C., Tusi, B. K., Spreafico, F., Bévengut, M., Gestreau, C., Buontempo, S., Simeone, A., Kruidenier, L., Natoli, G., Casola, S., Hilaire, G. & Testa, G., Nov 29 2012, In : Cell Reports. 2, 5, p. 1244-1258 15 p.

Research output: Contribution to journalArticle

Pacemakers
Neurogenesis
Methyltransferases
Histones
Lysine
49 Citations (Scopus)

The Histone Methyltransferase Wbp7 Controls Macrophage Function through GPI Glycolipid Anchor Synthesis

Austenaa, L., Barozzi, I., Chronowska, A., Termanini, A., Ostuni, R., Prosperini, E., Stewart, A. F., Testa, G. & Natoli, G., Apr 20 2012, In : Immunity. 36, 4, p. 572-585 14 p.

Research output: Contribution to journalArticle

Glycosylphosphatidylinositols
Glycolipids
Macrophages
Histones
Lipopolysaccharides
14 Citations (Scopus)

The Identity of Living Beings, Epigenetics, and the Modesty of Philosophy

Boniolo, G. & Testa, G., Mar 2012, In : Erkenntnis. 76, 2, p. 279-298 20 p.

Research output: Contribution to journalArticle

Persistence
Phenotype
Molecular Biology
Genome
Continue
2011
106 Citations (Scopus)

Genomic instability in induced stem cells

Pasi, C. E., Dereli-Öz, A., Negrini, S., Friedli, M., Fragola, G., Lombardo, A., Van Houwe, G., Naldini, L., Casola, S., Testa, G., Trono, D., Pelicci, P. G. & Halazonetis, T. D., May 2011, In : Cell Death and Differentiation. 18, 5, p. 745-753 9 p.

Research output: Contribution to journalArticle

Genomic Instability
Stem Cells
DNA Replication
Oncogenes
Breast
52 Citations (Scopus)

The Methyltransferase Set7/9 (Setd7) Is Dispensable for the p53-Mediated DNA Damage Response In Vivo

Campaner, S., Spreafico, F., Burgold, T., Doni, M., Rosato, U., Amati, B. & Testa, G., Aug 19 2011, In : Molecular Cell. 43, 4, p. 681-688 8 p.

Research output: Contribution to journalArticle

Methyltransferases
DNA Damage
p53 Genes
Acetylation
Apoptosis
19 Citations (Scopus)

The time of timing: How Polycomb proteins regulate neurogenesis

Testa, G., Jul 2011, In : BioEssays. 33, 7, p. 519-528 10 p.

Research output: Contribution to journalArticle

Polycomb-Group Proteins
Gene Targeting
Neurogenesis
Post Translational Protein Processing
Ablation
2009
9 Citations (Scopus)

Ethics Report on Interspecies Somatic Cell Nuclear Transfer Research

Skene, L., Testa, G., Hyun, I., Jung, KW., McNab, A., Robertson, J., Scott, CT., Solbakk, J. H., Taylor, P. & Zoloth, L., Jul 2 2009, In : Cell Stem Cell. 5, 1, p. 27-30 4 p.

Research output: Contribution to journalArticle

Ethics
Embryo Transfer
Research
8 Citations (Scopus)

IL-16 can synergize with early acting cytokines to expand ex vivo CD34 + isolated from cord blood

Rofani, C., Luchetti, L., Testa, G., Lasorella, R., Isacchi, G., Bottazzo, G. F. & Berardi, A. C., May 1 2009, In : Stem Cells and Development. 18, 4, p. 671-682 12 p.

Research output: Contribution to journalArticle

Interleukin-16
Fetal Blood
Cytokines
Stem Cells
Thrombopoietin
253 Citations (Scopus)

Jmjd3 contributes to the control of gene expression in LPS-activated macrophages

De Santa, F., Narang, V., Yap, Z. H., Tusi, B. K., Burgold, T., Austenaa, L., Bucci, G., Caganova, M., Notarbartolo, S., Casola, S., Testa, G., Sung, W. K., Wei, C. L. & Natoli, G., Nov 2009, In : EMBO Journal. 28, 21, p. 3341-3352 12 p.

Research output: Contribution to journalArticle

Macrophages
Gene expression
Lipopolysaccharides
Genes
Gene Expression

Nuclear transfer: An example of responsive epistemologies

Testa, G., Dec 2009, In : Current Science. 97, 11, p. 1621-1624 4 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

The future therapeutic potential of histone demethylases: A critical analysis

Natoli, G., Testa, G. & De Santa, F., Sep 2009, In : Current Opinion in Drug Discovery and Development. 12, 5, p. 607-615 9 p.

Research output: Contribution to journalArticle

Histone Demethylases
Histone Code
Histones
Methylation
Drug Delivery Systems
7 Citations (Scopus)

What to Do with the Grail Now that We Have It? iPSCs, Potentiality, and Public Policy

Testa, G., Oct 2 2009, In : Cell Stem Cell. 5, 4, p. 358-359 2 p.

Research output: Contribution to journalArticle

2008
13 Citations (Scopus)

Bacterial artificial chromosome transgenesis through pronuclear injection of fertilized mouse oocytes.

Vintersten, K., Testa, G., Naumann, R., Anastassiadis, K. & Stewart, A. F., 2008, In : Methods in molecular biology (Clifton, N.J.). 415, p. 83-100 18 p.

Research output: Contribution to journalArticle

Bacterial Artificial Chromosomes
Gene Transfer Techniques
Oocytes
Injections
Transgenes
115 Citations (Scopus)

Mast cell-specific Cre/loxP-mediated recombination in vivo

Scholten, J., Hartmann, K., Gerbaulet, A., Krieg, T., Müller, W., Testa, G. & Roers, A., Apr 2008, In : Transgenic Research. 17, 2, p. 307-315 9 p.

Research output: Contribution to journalArticle

mast cells
Mast Cells
Genetic Recombination
mice
promoter regions
1 Citation (Scopus)

Pluripotency and differentiation in embryos and stem cells

Adjaye, J. A., Byskov, A. G., Cibelli, J. B., De Maria, R., Minger, S., Sampaolesia, M., Testa, G., Verfaillie, C., Zernicka-Goetz, M., Schölef, H., Boiani, M., Crosetto, N. & Redi, G. A., 2008, In : International Journal of Developmental Biology. 52, 7, p. 801-809 9 p.

Research output: Contribution to journalArticle

141 Citations (Scopus)

The histone H3 lysine 27-specific demethylase Jmjd3 is required for neural commitment

Burgold, T., Spreafico, F., De Santa, F., Totaro, M. G., Prosperini, E., Natoli, G. & Testa, G., Aug 21 2008, In : PLoS One. 3, 8, e3034.

Research output: Contribution to journalArticle

histones
Histones
Lysine
lysine
Neural Stem Cells
2007
19 Citations (Scopus)

Breakdown of the Potentiality Principle and Its Impact on Global Stem Cell Research

Testa, G., Borghese, L., Steinbeck, J. A. & Brüstle, O., Aug 16 2007, In : Cell Stem Cell. 1, 2, p. 153-156 4 p.

Research output: Contribution to journalArticle

Stem Cell Research
Berlin
Politics
Legislation
Germany
48 Citations (Scopus)

Ethical standards for human-to-animal chimera experiments in stem cell research.

Hyun, I., Taylor, P., Testa, G., Dickens, B., Jung, K. W., McNab, A., Robertson, J., Skene, L. & Zoloth, L., Aug 16 2007, In : Cell Stem Cell. 1, 2, p. 159-163 5 p.

Research output: Contribution to journalArticle

588 Citations (Scopus)

The Histone H3 Lysine-27 Demethylase Jmjd3 Links Inflammation to Inhibition of Polycomb-Mediated Gene Silencing

De Santa, F., Totaro, M. G., Prosperini, E., Notarbartolo, S., Testa, G. & Natoli, G., Sep 21 2007, In : Cell. 130, 6, p. 1083-1094 12 p.

Research output: Contribution to journalArticle

Macrophages
Gene Silencing
Histones
Lysine
Genes