1978 …2019

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2019

Interferon-inducible TRIM22 contributes to maintenance of HIV-1 proviral latency in T cell lines

Turrini, F., Saliu, F., Forlani, G., Das, A. T., Van Lint, C., Accolla, R. S., Berkhout, B., Poli, G. & Vicenzi, E., Aug 2019, In : Virus Research. 269, 197631.

Research output: Contribution to journalArticle

2018

Reversible Human Immunodeficiency Virus Type-1 Latency in Primary Human Monocyte-Derived Macrophages Induced by Sustained M1 Polarization

Graziano, F., Aimola, G., Forlani, G., Turrini, F., Accolla, RS., Vicenzi, E. & Poli, G., 2018, In : Scientific Reports. 8, 14249.

Research output: Contribution to journalArticle

The interferon-stimulated gene TRIM22: A double-edged sword in HIV-1 infection

Vicenzi, E. & Poli, G., 2018, In : Cytokine and Growth Factor Reviews. 40, 3, p. 40-47 8 p.

Research output: Contribution to journalArticle

2017

5-Hydroxytyrosol inhibits HIV-1 replication in primary cells of the lower and upper female reproductive tract

Saba, E., Panina, P., Pagani, I., Origoni, M., Candiani, M., Doglioni, C., Taccagni, G. L., Ghezzi, S., Alcami, J., Vicenzi, E. & Poli, G., 2017, In : Antiviral Research. 142, 4, p. 16-20 5 p.

Research output: Contribution to journalArticle

Activating Killer Immunoglobulin Receptors and HLA-C: A successful combination providing HIV-1 control

Malnati, MS., Ugolotti, E., Monti, MC., De Battista, D., Vanni, I., Bordo, D., Sironi, F., Larghero, P., Di Marco, E., Biswas, P., Poli, G., Vicenzi, E., Riva, A., Tarkowski, M., Tambussi, G., Nozza, S., Tripodi, G., Marras, F., De Maria, A., Pistorio, A. & 1 others, Biassoni, R., 2017, In : Scientific Reports. 7, 25, 42470.

Research output: Contribution to journalArticle

HIV-1-mediated insertional activation of STAT5B and BACH2 trigger viral reservoir in T regulatory cells

Cesana, D., Santoni De Sio, FR., Rudilosso, L., Gallina, P., Calabria, A., Beretta, S., Merelli, I., Bruzzesi, E., Passerini, L., Nozza, S., Vicenzi, E., Poli, G., Gregori, S., Tambussi, G. & Montini, E., 2017, In : Nature Communications. 8, 1, 498.

Research output: Contribution to journalArticle

Human endometrial stromal cells are highly permissive to productive infection by zika virus

Pagani, I., Ghezzi, S., Ulisse, A., Rubio, A., Turrini, F., Garavaglia, E., Candiani, M., Castilletti, C., Ippolito, G., Poli, G., Broccoli, V., Panina-Bordignon, P. & Vicenzi, E., Mar 10 2017, In : Scientific Reports. 7, 44286.

Research output: Contribution to journalArticle

Human endometrial stromal cells are highly permissive to productive infection by zika virus

Pagani, I., Ghezzi, S., Ulisse, A., Rubio, A., Turrini, F., Garavaglia, E., Candiani, M., Castilletti, C., Ippolito, G., Poli, G., Broccoli, V., Panina, P. & Vicenzi, E., 2017, In : Scientific Reports. 7, 44286.

Research output: Contribution to journalArticle

2016

Plastic restriction of HIV-1 replication in human macrophages derived from M1/M2 polarized monocytes

Graziano, F., Vicenzi, E. & Poli, G., Nov 1 2016, In : Journal of Leukocyte Biology. 100, 5, p. 1147-1153 7 p.

Research output: Contribution to journalArticle

The MHC-II transactivator CIITA inhibits Tat function and HIV-1 replication in human myeloid cells

Forlani, G., Turrini, F., Ghezzi, S., Tedeschi, A., Poli, G., Accolla, R. S. & Tosi, G., Apr 18 2016, In : Journal of Translational Medicine. 14, 1, 94.

Research output: Contribution to journalArticle

2015

CD14+ macrophages that accumulate in the colon of African AIDS patients express pro-inflammatory cytokines and are responsive to lipopolysaccharide

Cassol, E., Rossouw, T., Malfeld, S., Mahasha, P., Slavik, T., Seebregts, C., Bond, R., du Plessis, J., Janssen, C., Roskams, T., Nevens, F., Alfano, M., Poli, G. & van der Merwe, S. W., Oct 17 2015, In : BMC Infectious Diseases. 15, 1

Research output: Contribution to journalArticle

Extracellular ATP induces the rapid release of HIV-1 from virus containing compartments of human macrophages

Graziano, F., Desdouits, M., Garzetti, L., Podini, P., Alfano, M., Rubartelli, A., Furlan, R., Benaroch, P. & Poli, G., Jun 23 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 25, p. E3265-E3273

Research output: Contribution to journalArticle

Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load

McLaren, P. J., Coulonges, C., Bartha, I., Lenz, T. L., Deutsch, A. J., Bashirova, A., Buchbinder, S., Carrington, M. N., Cossarizza, A., Dalmau, J., De Luca, A., Goedert, J. J., Gurdasani, D., Haas, D. W., Herbeck, J. T., Johnson, E. O., Kirk, G. D., Lambotte, O., Luo, M., Mallal, S. & 21 others, Van Manen, D., Martinez-Picado, J., Meyer, L., Miro, J. M., Mullins, J. I., Obel, N., Poli, G., Sandhu, M. S., Schuitemaker, H., Shea, P. R., Theodorou, I., Walker, B. D., Weintrob, A. C., Winkler, C. A., Wolinsky, S. M., Raychaudhuri, S., Goldstein, D. B., Telenti, A., De Bakker, P. I. W., Zagury, J. F. & Fellay, J., Nov 24 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 47, p. 14658-14663 6 p.

Research output: Contribution to journalArticle

2014

Preface

Vicenzi, E. & Poli, G., 2014, In : Methods in molecular biology (Clifton, N.J.). 1087

Research output: Contribution to journalArticle

Spontaneous control of HIV-1 viremia in a subject with protective HLA-B plus HLA-C alleles and HLA-C associated single nucleotide polymorphisms

Moroni, M., Ghezzi, S., Baroli, P., Heltai, S., De Battista, D., Pensieroso, S., Cavarelli, M., Dispinseri, S., Vanni, I., Pastori, C., Zerbi, P., Tosoni, A., Vicenzi, E., Nebuloni, M., Wong, K., Zhao, H., McHugh, S., Poli, G., Lopalco, L., Scarlatti, G. & 4 others, Biassoni, R., Mullins, J. I., Malnati, M. S. & Alfano, M., Dec 5 2014, In : Journal of Translational Medicine. 12, 1, 335.

Research output: Contribution to journalArticle

2013

Association Study of Common Genetic Variants and HIV-1 Acquisition in 6,300 Infected Cases and 7,200 Controls

McLaren, P. J., Coulonges, C., Ripke, S., van den Berg, L., Buchbinder, S., Carrington, M., Cossarizza, A., Dalmau, J., Deeks, S. G., Delaneau, O., De Luca, A., Goedert, J. J., Haas, D., Herbeck, J. T., Kathiresan, S., Kirk, G. D., Lambotte, O., Luo, M., Mallal, S., van Manen, D. & 26 others, Martinez-Picado, J., Meyer, L., Miro, J. M., Mullins, J. I., Obel, N., O'Brien, S. J., Pereyra, F., Plummer, F. A., Poli, G., Qi, Y., Rucart, P., Sandhu, M. S., Shea, P. R., Schuitemaker, H., Theodorou, I., Vannberg, F., Veldink, J., Walker, B. D., Weintrob, A., Winkler, C. A., Wolinsky, S., Telenti, A., Goldstein, D. B., de Bakker, P. I. W., Zagury, J. F. & Fellay, J., Jul 2013, In : PLoS Pathogens. 9, 7, e1003515.

Research output: Contribution to journalArticle

Dendritic cell-specific intercellular adhesion molecule-3 grabbing nonintegrin mediates HIV-1 infection of and transmission by M2a-polarized macrophages in vitro

Cassol, E., Cassetta, L., Rizzi, C., Gabuzda, D., Alfano, M. & Poli, G., Mar 13 2013, In : AIDS (London, England). 27, 5, p. 707-716 10 p.

Research output: Contribution to journalArticle

HIV-1 Infected Lymphoid Organs Upregulate Expression and Release of the Cleaved Form of uPAR That Modulates Chemotaxis and Virus Expression

Nebuloni, M., Zawada, L., Ferri, A., Tosoni, A., Zerbi, P., Resnati, M., Poli, G., Genovese, L. & Alfano, M., Jul 29 2013, In : PLoS One. 8, 7, e70606.

Research output: Contribution to journalArticle

Identification of TRIM22 single nucleotide polymorphisms associated with loss of inhibition of HIV-1 transcription and advanced HIV-1 disease

Ghezzi, S., Galli, L., Kajaste-Rudnitski, A., Turrini, F., Marelli, S., Toniolo, D., Casoli, C., Riva, A., Poli, G., Castagna, A. & Vicenzi, E., Sep 24 2013, In : AIDS (London, England). 27, 15, p. 2335-2344 10 p.

Research output: Contribution to journalArticle

Impaired CD4+ T-cell restoration in the small versus large intestine of HIV-1-positive South Africans receiving combination antiretroviral therapy

Cassol, E., Malfeld, S., Mahasha, P., Bond, R., Slavik, T., Seebregts, C., Poli, G., Cassol, S., Van Der Merwe, S. W. & Rossouw, T., Oct 1 2013, In : Journal of Infectious Diseases. 208, 7, p. 1113-1122 10 p.

Research output: Contribution to journalArticle

M1 polarization of human monocyte-derived macrophages restricts pre and postintegration steps of HIV-1 replication

Cassetta, L., Kajaste-Rudnitski, A., Coradin, T., Saba, E., Della Chiara, G., Barbagallo, M., Graziano, F., Alfano, M., Cassol, E., Vicenzi, E. & Poli, G., Jul 31 2013, In : AIDS (London, England). 27, 12, p. 1847-1856 10 p.

Research output: Contribution to journalArticle

Macrophage polarization at the crossroad between hiv-1 infection and cancer development

Alfano, M., Graziano, F., Genovese, L. & Poli, G., Jun 2013, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 33, 6, p. 1145-1152 8 p.

Research output: Contribution to journalArticle

Novel factors interfering with human immunodeficiency virus-type 1 replication in vivo and in vitro

Vicenzi, E. & Poli, G., Feb 2013, In : Tissue Antigens. 81, 2, p. 61-71 11 p.

Research output: Contribution to journalArticle

Productive HIV-1 infection of human cervical tissue ex vivo is associated with the secretory phase of the menstrual cycle

Saba, E., Origoni, M., Taccagni, G., Ferrari, D., Doglioni, C., Nava, A., Lisco, A., Grivel, J. C., Margolis, L. & Poli, G., Nov 2013, In : Mucosal Immunology. 6, 6, p. 1081-1090 10 p.

Research output: Contribution to journalArticle

The puzzling role of CXCR4 in human immunodeficiency virus infection

Vicenzi, E., Liò, P. & Poli, G., 2013, In : Theranostics. 3, 1, p. 18-25 8 p.

Research output: Contribution to journalArticle

2012

A general strategy to endow natural fusion-protein-derived peptides with potent antiviral activity

Pessi, A., Langella, A., Capitò, E., Ghezzi, S., Vicenzi, E., Poli, G., Ketas, T., Mathieu, C., Cortese, R., Horvat, B., Moscona, A. & Porotto, M., May 16 2012, In : PLoS One. 7, 5, e36833.

Research output: Contribution to journalArticle

Amino acid starvation induces reactivation of silenced transgenes and latent HIV-1 provirus via down-regulation of histone deacetylase 4 (HDAC4)

Palmisano, I., Della Chiara, G., D'Ambrosio, R. L., Huichalaf, C., Brambilla, P., Corbetta, S., Riba, M., Piccirillo, R., Valente, S., Casari, G., Mai, A., Boneschi, F. M., Gabellini, D., Poli, G. & Schiaffino, M. V., Aug 21 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 34

Research output: Contribution to journalArticle

A new antigen scanning strategy for monitoring HIV-1 specific T-cell immune responses

Malnati, M. S., Heltai, S., Cosma, A., Reitmeir, P., Allgayer, S., Glashoff, R. H., Liebrich, W., Vardas, E., Imami, N., Westrop, S., Nozza, S., Tambussi, G., Buttò, S., Fanales-Belasio, E., Ensoli, B., Ensoli, F., Tripiciano, A., Fortis, C., Lusso, P., Poli, G. & 2 others, Erfle, V. & Holmes, H., Jan 31 2012, In : Journal of Immunological Methods. 375, 1-2, p. 46-56 11 p.

Research output: Contribution to journalArticle

Design and characterization of a peptide mimotope of the HIV-1 gp120 bridging sheet

Schiavone, M., Fiume, G., Caivano, A., de Laurentiis, A., Falcone, C., Masci, F. F., Iaccino, E., Mimmi, S., Palmieri, C., Pisano, A., Pontoriero, M., Rossi, A., Scialdone, A., Vecchio, E., Andreozzi, C., Trovato, M., Rafay, J., Ferko, B., Montefiori, D., Lombardi, A. & 6 others, Morsica, G., Poli, G., Quinto, I., Pavone, V., de Berardinis, P. & Scala, G., May 2012, In : International Journal of Molecular Sciences. 13, 5, p. 5674-5699 26 p.

Research output: Contribution to journalArticle

HIV-1 envelope-dependent restriction of CXCR4-using viruses in child but not adult untransformed CD4 + T-lymphocyte lines

Mariani, S. A., Brigida, I., Kajaste-Rudnitski, A., Ghezzi, S., Rocchi, A., Plebani, A., Vicenzi, E., Aiuti, A. & Poli, G., Mar 1 2012, In : Blood. 119, 9, p. 2013-2023 11 p.

Research output: Contribution to journalArticle

Single-nucleotide polymorphism-defined class i and class III major histocompatibility complex genetic subregions contribute to natural long-term nonprogression in HIV infection

Guergnon, J., Dalmasso, C., Broet, P., Meyer, L., Westrop, S. J., Imami, N., Vicenzi, E., Morsica, G., Tinelli, M., Zanone Poma, B., Goujard, C., Potard, V., Gotch, F. M., Casoli, C., Cossarizza, A., MacCiardi, F., Debré, P., Delfraissy, J. F., Galli, M., Autran, B. & 4 others, Costagliola, D., Poli, G., Theodorou, I. & Riva, A., Mar 1 2012, In : Journal of Infectious Diseases. 205, 5, p. 718-724 7 p.

Research output: Contribution to journalArticle

Towards an HIV cure: A global scientific strategy

Deeks, S. G., Autran, B., Berkhout, B., Benkirane, M., Cairns, S., Chomont, N., Chun, T. W., Churchill, M., Mascio, M. D., Katlama, C., Lafeuillade, A., Landay, A., Lederman, M., Lewin, S. R., Maldarelli, F., Margolis, D., Markowitz, M., Martinez-Picado, J., Mullins, J. I., Mellors, J. & 16 others, Moreno, S., O'doherty, U., Palmer, S., Penicaud, M. C., Peterlin, M., Poli, G., Routy, J. P., Rouzioux, C., Silvestri, G., Stevenson, M., Telenti, A., Lint, C. V., Verdin, E., Woolfrey, A., Zaia, J. & Barré-Sinoussi, F., Aug 2012, In : Nature Reviews Immunology. 12, 8, p. 607-614 8 p.

Research output: Contribution to journalArticle

Macrophage polarization in health and disease

Cassetta, L., Cassol, E. & Poli, G., 2011, In : TheScientificWorldJournal. 11, p. 2391-2402 12 p.

Research output: Contribution to journalArticle

Major histocompatibility complex class II transactivator CIITA is a viral restriction factor that targets human T-cell lymphotropic virus type 1 tax-1 function and inhibits viral replication

Tosi, G., Forlani, G., Andresen, V., Turci, M., Bertazzoni, U., Franchini, G., Poli, G. & Accolla, R. S., Oct 2011, In : Journal of Virology. 85, 20, p. 10719-10729 11 p.

Research output: Contribution to journalArticle

Negative regulation of HIV-1 transcription by a heterodimeric NF-κB1/p50 and C-terminally truncated STAT5 complex

Della Chiara, G., Crotti, A., Liboi, E., Giacca, M., Poli, G. & Lusic, M., Jul 29 2011, In : Journal of Molecular Biology. 410, 5, p. 933-943 11 p.

Research output: Contribution to journalArticle

Old and new plasma biomarkers in HIV-1-infected African-American women

Poli, G., Sep 24 2011, In : AIDS (London, England). 25, 15, p. 1921-1923 3 p.

Research output: Contribution to journalArticle

Strenuous resistance to natural HIV-1 disease progression: Viral controllers and long-term nonprogressors

Riva, A., Vicenzi, E., Galli, M. & Poli, G., Apr 2011, In : Future Virology. 6, 4, p. 521-533 13 p.

Research output: Contribution to journalArticle

TRIM22 inhibits HIV-1 transcription independently of Its E3 ubiquitin ligase activity, Tat, and NF-κB-responsive long terminal repeat elements

Kajaste-Rudnitski, A., Marelli, S. S., Pultrone, C., Pertel, T., Uchil, P. D., Mechti, N., Mothes, W., Poli, G., Luban, J. & Vicenzi, E., May 2011, In : Journal of Virology. 85, 10, p. 5183-5196 14 p.

Research output: Contribution to journalArticle

Urokinase plasminogen activator inhibits HIV virion release from macrophage-differentiated chronically infected cells via activation of RhoA and PKCε

Graziano, F., Elia, C., Laudanna, C., Poli, G. & Alfano, M., 2011, In : PLoS One. 6, 8, e23674.

Research output: Contribution to journalArticle

2010

Asymmetric HIV-1 co-receptor use and replication in CD4+ T lymphocytes

Mariani, S. A., Vicenzi, E. & Poli, G., Jan 27 2010, In : Journal of Translational Medicine. 9, SUPPL. 1, S8.

Research output: Contribution to journalArticle

Characterization of HIV type 1 genetic diversity among South African participants enrolled in the AIDS Vaccine Integrated Project (AVIP) Study

Papathanasopoulos, M. A., Vardas, E., Wallis, C., Glashoff, R., Buttó, S., Poli, G., Malnati, M., Clerici, M. & Ensoli, B., Jun 1 2010, In : AIDS Research and Human Retroviruses. 26, 6, p. 705-709 5 p.

Research output: Contribution to journalArticle

Macrophage polarization and HIV-1 infection

Cassol, E., Cassetta, L., Alfano, M. & Poli, G., Apr 2010, In : Journal of Leukocyte Biology. 87, 4, p. 599-608 10 p.

Research output: Contribution to journalArticle

Nef-specific CD45RA+ CD8+ T cells secreting MIP-1β but not IFN-γ are associated with nonprogressive HIV-1 infection

Dembek, C. J., Kutscher, S., Heltai, S., Allgayer, S., Biswas, P., Ghezzi, S., Vicenzi, E., Hoffmann, D., Reitmeir, P., Tambussi, G., Bogner, J. R., Lusso, P., Stellbrink, H. J., Santagostino, E., Vollbrecht, T., Goebel, F. D., Protzer, U., Draenert, R., Tinelli, M., Poli, G. & 3 others, Erfle, V., Malnati, M. & Cosma, A., Jul 2 2010, In : AIDS Research and Therapy. 7, 20.

Research output: Contribution to journalArticle

Persistence of CCR5 usage among primary human immunodeficiency virus isolates of individuals receiving intermittent interleukin-2

Ghezzi, S., Pacciarini, F., Nozza, S., Racca, S., Mariani, S. A., Vicenzi, E., Lazzarin, A., Veglia, F., Tambussi, G. & Poli, G., 2010, In : HIV Medicine. 11, 5, p. 349-352 4 p.

Research output: Contribution to journalArticle

Persistent microbial translocation and immune activation in HIV-1-infected south africans receiving combination antiretroviral therapy

Cassol, E., Malfeld, S., Mahasha, P., Van Der Merwe, S., Cassol, S., Seebregts, C., Alfano, M., Poli, G. & Rossouw, T., Sep 1 2010, In : Journal of Infectious Diseases. 202, 5, p. 723-733 11 p.

Research output: Contribution to journalArticle

The rise and fall of intermittent interleukin-2 therapy in HIV infection

Della Chiara, G., Fortis, C., Tambussi, G. & Poli, G., Sep 2010, In : European Cytokine Network. 21, 3, p. 197-201 5 p.

Research output: Contribution to journalArticle

2009

Ligand-engaged urokinase-type plasminogen activator receptor and activation of the CD11b/CD18 integrin inhibit late events of HIV expression in monocytic cells

Alfano, M., Mariani, S. A., Elia, C., Pardi, R., Blasi, F. & Poli, G., Feb 19 2009, In : Blood. 113, 8, p. 1699-1709 11 p.

Research output: Contribution to journalArticle