1993 …2019

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2019

Downregulation of miR-223 expression is an early event during mammary transformation and confers resistance to CDK4/6 inhibitors in luminal breast cancer

Citron, F., Segatto, I., Rampioni Vinciguerra, G. L., Musco, L., Russo, F., Mungo, G., D'Andrea, S., Mattevi, M. C., Perin, T., Schiappacassi, M., Massarut, S., Marchini, C., Amici, A., Vecchione, A., Baldassarre, G. & Belletti, B., Dec 20 2019, In : Cancer Research. p. canres.1793.2019

Research output: Contribution to journalArticle

Multiplex staining depicts the immune infiltrate in colitis-induced colon cancer model

Pivetta, E., Capuano, A., Scanziani, E., Minoli, L., Andreuzzi, E., Mongiat, M., Baldassarre, G., Doliana, R. & Spessotto, P., Dec 1 2019, In : Scientific Reports. 9, 1, 12 p., 12645.

Research output: Contribution to journalArticle

Open Access

Pathologist second opinion significantly alters clinical management of pT1 endoscopically resected colorectal cancer

Rampioni Vinciguerra, G. L., Antonelli, G., Citron, F., Berardi, G., Angeletti, S., Baldassarre, G., Vecchione, A., Di Giulio, E. & Pilozzi, E., Nov 1 2019, In : Virchows Archiv. 475, 5, p. 665-668 4 p.

Research output: Contribution to journalArticle

Sleeping beauty genetic screen identifies miR-23b::BTBD7 gene interaction as crucial for colorectal cancer metastasis

Grisard, E., Coan, M., Cesaratto, L., Rigo, I., Zandonà, L., Paulitti, A., Andreuzzi, E., Rampioni Vinciguerra, G. L., Poletto, E., Del Ben, F., Brisotto, G., Biscontin, E., Turetta, M., Dassi, E., Mirnezami, A., Canzonieri, V., Vecchione, A., Baldassarre, G., Mongiat, M., Spizzo, R. & 1 others, Nicoloso, M. S., Aug 2019, In : EBioMedicine. 46, p. 79-93 15 p.

Research output: Contribution to journalArticle

Open Access

Sleeping beauty genetic screen identifies miR-23b::BTBD7 gene interaction as crucial for colorectal cancer metastasis

Grisard, E., Coan, M., Cesaratto, L., Rigo, I., Zandonà, L., Paulitti, A., Andreuzzi, E., Rampioni Vinciguerra, G. L., Poletto, E., Del Ben, F., Brisotto, G., Biscontin, E., Turetta, M., Dassi, E., Mirnezami, A., Canzonieri, V., Vecchione, A., Baldassarre, G., Mongiat, M., Spizzo, R. & 1 others, Nicoloso, M. S., Aug 2019, In : EBioMedicine. 46, p. 79-93 15 p.

Research output: Contribution to journalArticle

Open Access

Stathmin is required for normal mouse mammary gland development and D16Her2-driven tumorigenesis

Segatto, I., De Marco Zompit, M., Citron, F., D'Andrea, S., Vinciguerra, G. L. R., Perin, T., Berton, S., Mungo, G., Schiappacassi, M., Marchini, C., Amici, A., Vecchione, A., Baldassarre, G. & Belletti, B., Jan 15 2019, In : Cancer Research. 79, 2, p. 397-409 13 p.

Research output: Contribution to journalArticle

The T197A Knock-in Model of Cdkn1b Gene to Study the Effects of p27 Restoration In Vivo

De Marco, C., Rinaldo, N., De Vita, F., Forzati, F., Caira, E., Iovane, V., Paciello, O., Montanaro, D., D'Andrea, S., Baldassarre, G., Papparella, S., Malanga, D., Baldi, A. & Viglietto, G., Feb 2019, In : Molecular Cancer Therapeutics. 18, 2, p. 482-493 12 p.

Research output: Contribution to journalArticle

TIMP-1 is Overexpressed and Secreted by Platinum Resistant Epithelial Ovarian Cancer Cells

Sonego, M., Poletto, E., Pivetta, E., Nicoloso, M. S., Pellicani, R., Vinciguerra, G. L. R., Citron, F., Sorio, R., Mongiat, M. & Baldassarre, G., Dec 18 2019, In : Cells. 9, 1, p. E6

Research output: Contribution to journalArticle

USP1 links platinum resistance to cancer cell dissemination by regulating Snail stability

Sonego, M., Pellarin, I., Costa, A., Vinciguerra, G. L. R., Coan, M., Kraut, A., D'Andrea, S., Dall'Acqua, A., Castillo-Tong, D. C., Califano, D., Losito, S., Spizzo, R., Couté, Y., Vecchione, A., Belletti, B., Schiappacassi, M. & Baldassarre, G., May 8 2019, In : Science advances. 5, 5, p. eaav3235-eaav3235 16 p.

Research output: Contribution to journalArticle

2018

Therapeutic decision based on molecular detection of resistance mechanism in an ALK-rearranged lung cancer patient: A case report

De Carlo, E., Schiappacassi, M., Urbani, M., Doliana, R., Baldassarre, G., Da Ros, V., Santarossa, S., Chimienti, E., Berto, E., Fratino, L. & Bearz, A., Jan 1 2018, In : OncoTargets and Therapy. 11, p. 8945-8950 6 p.

Research output: Contribution to journalArticle

The T197A knock-in model of Cdkn1b gene to study the effects of p27 restoration in vivo

De Marco, C., Rinaldo, N., De Vita, F., Forzati, F., Caira, E., Iovane, V., Paciello, O., Montanaro, D., D'Andrea, S., Baldassarre, G., Papparella, S., Malanga, D., Baldi, A. & Viglietto, G., Nov 13 2018, In : Molecular Cancer Therapeutics.

Research output: Contribution to journalArticle

2017

An integrated approach identifies mediators of local recurrence in head and neck squamous carcinoma

Citron, F., Armenia, J., Franchin, G., Polesel, J., Talamini, R., D'Andrea, S., Sulfaro, S., Croce, C. M., Klement, W., Otasek, D., Pastrello, C., Tokar, T., Jurisica, I., French, D., Bomben, R., Vaccher, E., Serraino, D., Belletti, B., Vecchione, A., Barzan, L. & 1 others, Baldassarre, G., Jul 15 2017, In : Clinical Cancer Research. 23, 14, p. 3769-3780 12 p.

Research output: Contribution to journalArticle

CDK6 protects epithelial ovarian cancer from platinum-induced death via FOXO3 regulation

Dall'Acqua, A., Sonego, M., Pellizzari, I., Pellarin, I., Canzonieri, V., D'Andrea, S., Benevol, S., Sorio, R., Giorda, G., Califano, D., Bagnoli, M., Militello, L., Mezzanzanica, D., Chiappetta, G., Armenia, J., Belletti, B., Schiappacassi, M. & Baldassarre, G., 2017, In : EMBO Molecular Medicine. 9, 10, p. 1415-1433 19 p.

Research output: Contribution to journalArticle

CDK6 protects epithelial ovarian cancer from platinum-induced death via FOXO3 regulation

Dall'Acqua, A., Sonego, M., Pellizzari, I., Pellarin, I., Canzonieri, V., D'Andrea, S., Benevol, S., Sorio, R., Giorda, G., Califano, D., Bagnoli, M., Militello, L., Mezzanzanica, D., Chiappetta, G., Armenia, J., Belletti, B., Schiappacassi, M. & Baldassarre, G., Oct 2017, In : EMBO Molecular Medicine. 9, 10, p. 1415-1433 19 p.

Research output: Contribution to journalArticle

Common biological phenotypes characterize the acquisition of platinum-resistance in epithelial ovarian cancer cells

Sonego, M., Pellizzari, I., Dall'Acqua, A., Pivetta, E., Lorenzon, I., Benevol, S., Bomben, R., Spessotto, P., Sorio, R., Gattei, V., Belletti, B., Schiappacassi, M. & Baldassarre, G., Dec 1 2017, In : Scientific Reports. 7, 1, 7104.

Research output: Contribution to journalArticle

Loss of p27kip1 increases genomic instability and induces radio-resistance in luminal breast cancer cells

Berton, S., Cusan, M., Segatto, I., Citron, F., D'Andrea, S., Benevol, S., Avanzo, M., Dall'Acqua, A., Schiappacassi, M., Bristow, R. G., Belletti, B. & Baldassarre, G., Dec 1 2017, In : Scientific Reports. 7, 1, 14 p., 595.

Research output: Contribution to journalArticle

2016

Biomarker analysis of the MITO2 phase III trial of first-line treatment in ovarian cancer: Predictive value of DNA-PK and phosphorylated ACC

Perrone, F., Baldassarre, G., Indraccolo, S., Signoriello, S., Chiappetta, G., Esposito, F., Ferrandina, G., Franco, R., Mezzanzanica, D., Sonego, M., Zulato, E., Zannoni, G. F., Canzonieri, V., Scambia, G., Sorio, R., Savarese, A., Breda, E., Scollo, P., Ferro, A., Tamberi, S. & 10 others, Febbraro, A., Natale, D., Di Maio, M., Califano, D., Scognamiglio, G., Lorusso, D., Canevari, S., Losito, N. S., Gallo, C. & Pignata, S., 2016, In : Oncotarget. 7, 45, p. 72654-72661 8 p.

Research output: Contribution to journalArticle

Development and validation of a microRNA-based signature (MiROvaR) to predict early relapse or progression of epithelial ovarian cancer: a cohort study

Bagnoli, M., Canevari, S., Califano, D., Losito, N. S., Maio, M. D., Raspagliesi, F., Carcangiu, M. L., Toffoli, G., Cecchin, E., Sorio, R., Canzonieri, V., Russo, D., Scognamiglio, G., Chiappetta, G., Baldassarre, G., Lorusso, D., Scambia, G., Zannoni, G. F., Savarese, A., Carosi, M. & 7 others, Scollo, P., Breda, E., Murgia, V., Perrone, F., Pignata, S., De Cecco, L. & Mezzanzanica, D., Aug 1 2016, In : The Lancet Oncology. 17, 8, p. 1137-1146 10 p.

Research output: Contribution to journalArticle

p27kip1 expression limits H-Ras-driven transformation and tumorigenesis by both canonical and non-canonical mechanisms

Pellizzari, I., Fabris, L., Berton, S., Segatto, I., Citron, F., D'Andrea, S., Cusan, M., Benevol, S., Perin, T., Massarut, S., Canzonieri, V., Schiappacassi, M., Belletti, B. & Baldassarre, G., 2016, In : Oncotarget. 7, 40, p. 64560-64574 15 p.

Research output: Contribution to journalArticle

Preclinical validation of a novel compound targeting p70S6 kinase in breast cancer

Segatto, I., Massarut, S., Boyle, R., Baldassarre, G., Walker, D. & Belletti, B., 2016, In : Aging. 8, 5, p. 958-976 19 p.

Research output: Contribution to journalArticle

Radiotherapy-induced miR-223 prevents relapse of breast cancer by targeting the EGF pathway

Fabris, L., Berton, S., Citron, F., D'Andrea, S., Segatto, I., Nicoloso, M. S., Massarut, S., Armenia, J., Zafarana, G., Rossi, S., Ivan, C., Perin, T., Vaidya, J. S., Avanzo, M., Roncadin, M., Schiappacassi, M., Bristow, R. G., Calin, G., Baldassarre, G. & Belletti, B., 2016, In : Oncogene. p. 4914-4926 13 p.

Research output: Contribution to journalArticle

SUMOylation regulates p27Kip1 stability and localization in response to TGFβ

Lovisa, S., Citro, S., Sonego, M., Dall'Acqua, A., Ranzuglia, V., Berton, S., Colombatti, A., Belletti, B., Chiocca, S., Baldassarre, G. & Schiappacassi, M., 2016, In : Journal of Molecular Cell Biology. 8, 1, p. 17-30 14 p.

Research output: Contribution to journalArticle

SUMOylation regulates p27Kip1 stability and localization in response to TGFβ

Lovisa, S., Citro, S., Sonego, M., Dall'Acqua, A., Ranzuglia, V., Berton, S., Colombatti, A., Belletti, B., Chiocca, S., Schiappacassi, M. & Baldassarre, G., 2016, In : Journal of Molecular Cell Biology. 8, 1, p. 17-30 14 p.

Research output: Contribution to journalArticle

2015

Mutant AKT1-E17K is oncogenic in lung epithelial cells

De Marco, C., Malanga, D., Rinaldo, N., De Vita, F., Scrima, M., Lovisa, S., Fabris, L., Carriero, M. V., Franco, R., Rizzuto, A., Baldassarre, G. & Viglietto, G., 2015, In : Oncotarget. 6, 37, p. 39634-39650 17 p.

Research output: Contribution to journalArticle

P27kip1 controls H-Ras/MAPK activation and cell cycle entry via modulation of MT stability

Fabris, L., Berton, S., Pellizzari, I., Segatto, I., D'Andrea, S., Armenia, J., Bomben, R., Schiappacassi, M., Gattei, V., Philips, M. R., Vecchione, A., Belletti, B. & Baldassarre, G., Nov 10 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 45, p. 13916-13921 6 p.

Research output: Contribution to journalArticle

Roles of CDKN1B in cancer?

Belletti, B. & Baldassarre, G., 2015, In : Aging. 7, 8, p. 529-530 2 p.

Research output: Contribution to journalArticle

Time-tuning cancer therapy

Baldassarre, G., Segatto, I. & Belletti, B., 2015, In : Aging. 7, 8, p. 531-532 2 p.

Research output: Contribution to journalArticle

Wound response after intraoperative radiotherapy

Massarut, S., Belletti, B., Segatto, I., Piccoli, E. & Baldassarre, G., Apr 1 2015, In : Translational Cancer Research. 4, 2, p. 161-172 12 p.

Research output: Contribution to journalArticle

2014

C1q as a unique player in angiogenesis with therapeutic implication in wound healing

Bossi, F., Tripodo, C., Rizzi, L., Bulla, R., Agostinis, C., Guarnotta, C., Munaut, C., Baldassarre, G., Papa, G., Zorzet, S., Ghebrehiwet, B., Ling, G. S., Botto, M. & Tedesco, F., Mar 18 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 11, p. 4209-4214 6 p.

Research output: Contribution to journalArticle

Contact inhibition modulates intracellular levels of miR-223 in a p27kip1-dependent manner

Armenia, J., Fabris, L., Lovat, F., Berton, S., Segatto, I., D'Andrea, S., Ivan, C., Calin, C. A., Croce, C. M., Colombatti, A., Vecchione, A., Belletti, B. & Baldassarre, G., 2014, In : Oncotarget. 5, 5, p. 1185-1197 13 p.

Research output: Contribution to journalArticle

Corrigendum to Stathmin regulates mutant p53 stability and transcriptional activity in ovarian cancer [EMBO Molecular Medicine]

Sonego, M., Schiappacassi, M., Lovisa, S., Dall'Acqua, A., Bagnoli, M., Lovat, F., Libra, M., D'Andrea, S., Canzonieri, V., Militello, L., Napoli, M., Giorda, G., Pivetta, B., Mezzanzanica, D., Barbareschi, M., Valeri, B., Canevari, S., Colombatti, A., Belletti, B., Del Sal, G. & 1 others, Baldassarre, G., Feb 2014, In : EMBO Molecular Medicine. 6, 2, p. 295 1 p.

Research output: Contribution to journalArticle

Genetic characterization of p27kip1and stathmin in controlling cell proliferation in vivo

Berton, S., Pellizzari, I., Fabris, L., D'Andrea, S., Segatto, I., Canzonieri, V., Marconi, D., Schiappacassi, M., Benevol, S., Gattei, V., Colombatti, A., Beletti, B. & Baldassarre, G., Oct 1 2014, In : Cell Cycle. 13, 19, p. 3100-3111 12 p.

Research output: Contribution to journalArticle

LZTS1 downregulation confers paclitaxel resistance and is associated with worse prognosis in breast cancer

Lovat, F., Ishii, H., Schiappacassi, M., Fassan, M., Barbareschi, M., Galligioni, E., Gasparini, P., Baldassarre, G., Croce, C. M. & Vecchione, A., 2014, In : Oncotarget. 5, 4, p. 970-977 8 p.

Research output: Contribution to journalArticle

P70S6 kinase mediates breast cancer cell survival in response to surgical wound fluid stimulation

Segatto, I., Berton, S., Sonego, M., Massarut, S., Fabris, L., Armenia, J., Mileto, M., Colombatti, A., Vecchione, A., Baldassarre, G. & Belletti, B., 2014, In : Molecular Oncology. 8, 3, p. 766-780 15 p.

Research output: Contribution to journalArticle

Prognostic role of bowel involvement in optimally cytoreduced advanced ovarian cancer: A retrospective study

Giorda, G., Gadducci, A., Lucia, E., Sorio, R., Bounous, V. E., Sopracordevole, F., Tinelli, A., Baldassarre, G. & Campagnutta, E., Jul 9 2014, In : Journal of Ovarian Research. 7, 1, 72.

Research output: Contribution to journalArticle

Surgery-induced wound response promotes stem-like and tumor-initiating features of breast cancer cells, via STAT3 signaling

Segatto, I., Berton, S., Sonego, M., Massarut, S., Perin, T., Piccoli, E., Colombatti, A., Vecchione, A., Baldassarre, G. & Belletti, B., 2014, In : Oncotarget. 5, 15, p. 6267-6279 13 p.

Research output: Contribution to journalArticle

2013

A microRNA signature defines chemoresistance in ovarian cancer through modulation of angiogenesis

Vecchione, A., Belletti, B., Lovat, F., Volinia, S., Chiappetta, G., Giglio, S., Sonego, M., Cirombella, R., Onesti, E. C., Pellegrini, P., Califano, D., Pignata, S., Losito, S., Canzonieri, V., Sorio, R., Alder, H., Wernicke, D., Stoppacciaro, A., Baldassarre, G. & Croce, C. M., Jun 11 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 24, p. 9845-9850 6 p.

Research output: Contribution to journalArticle

Inhibition of breast cancer local relapse by targeting p70S6 kinase activity

Segatto, I., Berton, S., Sonego, M., Massarut, S., D'Andrea, S., Perin, T., Fabris, L., Armenia, J., Rampioni, G., Lovisa, S., Schiappacassi, M., Colombatti, A., Bristow, R. G., Vecchione, A., Baldassarre, G. & Belletti, B., Dec 2013, In : Journal of Molecular Cell Biology. 5, 6, p. 428-431 4 p.

Research output: Contribution to journalArticle

Stathmin regulates mutant p53 stability and transcriptional activity in ovarian cancer

Sonego, M., Schiappacassi, M., Lovisa, S., Dall'Acqua, A., Bagnoli, M., Lovat, F., Libra, M., D'Andrea, S., Canzonieri, V., Militello, L., Napoli, M., Giorda, G., Pivetta, B., Mezzanzanica, D., Barbareschi, M., Valeri, B., Canevari, S., Colombatti, A., Belletti, B., Del Sal, G. & 1 others, Baldassarre, G., May 2013, In : EMBO Molecular Medicine. 5, 5, p. 707-722 16 p.

Research output: Contribution to journalArticle

2012

Alteration of G1/S transition regulators influences recurrences in head and neck squamous carcinomas

Canzonieri, V., Barzan, L., Franchin, G., Vaccher, E., Talamini, R., Sulfaro, S. & Baldassarre, G., Jan 2012, In : Journal of Cellular Physiology. 227, 1, p. 233-238 6 p.

Research output: Contribution to journalArticle

New light on p27kip1 in breast cancer

Belletti, B. & Baldassarre, G., Oct 1 2012, In : Cell Cycle. 11, 19, p. 3701-3702 2 p.

Research output: Contribution to journalArticle

Stathmin Is Dispensable for Tumor Onset in Mice

D'Andrea, S., Berton, S., Segatto, I., Fabris, L., Canzonieri, V., Colombatti, A., Vecchione, A., Belletti, B. & Baldassarre, G., Sep 20 2012, In : PLoS One. 7, 9, e45561.

Research output: Contribution to journalArticle

2011

Role of T198 modification in the regulation of p27Kip1 protein stability and function

Schiappacassi, M., Lovisa, S., Lovat, F., Fabris, L., Colombatti, A., Belletti, B. & Baldassarre, G., 2011, In : PLoS One. 6, 3, e17673.

Research output: Contribution to journalArticle

Stathmin: A protein with many tasks. New biomarker and potential target in cancer

Belletti, B. & Baldassarre, G., Nov 2011, In : Expert Opinion on Therapeutic Targets. 15, 11, p. 1249-1266 18 p.

Research output: Contribution to journalArticle

2010

p27kip1 controls cell morphology and motility by regulating microtubule-dependent lipid raft recycling

Belletti, B., Pellizzari, I., Berton, S., Fabris, L., Wolf, K., Lovat, F., Schiappacassi, M., D'Andrea, S., Nicoloso, M. S., Lovisa, S., Sonego, M., Defilippi, P., Vecchione, A., Colombatti, A., Friedl, P. & Baldassarre, G., May 2010, In : Molecular and Cellular Biology. 30, 9, p. 2229-2240 12 p.

Research output: Contribution to journalArticle

Role of glucocorticoids in breast cancer

Vaidya, J. S., Baldassarre, G., Thorat, M. A. & Massarut, S., 2010, In : Current Pharmaceutical Design. 16, 32, p. 3593-3600 8 p.

Research output: Contribution to journalArticle

MicroRNAs: The jack of all trades

Rehman, S. K., Baldassarre, G., Calin, G. A. & Nicoloso, M. S., Feb 2009, In : Clinical Leukemia. 3, 1, p. 20-32 13 p.

Research output: Contribution to journalArticle

MITOSTATIN, a putative tumor suppressor on chromosome 12q24.1, is downregulated in human bladder and breast cancer

Vecchione, A., Fassan, M., Anesti, V., Morrione, A., Goldoni, S., Baldassarre, G., Byrne, D., D'Arca, D., Palazzo, J. P., Lloyd, J., Scorrano, L., Gomella, L. G., Iozzo, R. V. & Baffa, R., Jan 15 2009, In : Oncogene. 28, 2, p. 257-269 13 p.

Research output: Contribution to journalArticle

The tumor suppressor functions of p27kip1 include control of the mesenchymal/amoeboid transition

Berton, S., Belletti, B., Wolf, K., Canzonieri, V., Lovat, F., Vecchione, A., Colombatti, A., Friedl, P. & Baldassarre, G., Sep 2009, In : Molecular and Cellular Biology. 29, 18, p. 5031-5045 15 p.

Research output: Contribution to journalArticle