20162019

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Article

ATM kinase sustains breast cancer stem-like cells by promoting ATG4C expression and autophagy

Antonelli, M., Strappazzon, F., Arisi, I., Brandi, R., D'Onofrio, M., Sambucci, M., Manic, G., Vitale, I., Barilà, D. & Stagni, V., Jan 1 2017, In : Oncotarget. 8, 13, p. 21692-21709 18 p.

Research output: Contribution to journalArticle

ATM kinase sustains breast cancer stem-like cells by promoting ATG4C expression and autophagy

Antonelli, M., Strappazzon, F., Arisi, I., Brandi, R., D'Onofrio, M., Sambucci, M., Manic, G., Vitale, I., Barila, D. & Stagni, V., Mar 28 2017, In : Oncotarget. 8, 13, p. 21692-21709 18 p.

Research output: Contribution to journalArticle

CHK1-targeted therapy to deplete DNA replication-stressed, p53-deficient, hyperdiploid colorectal cancer stem cells

Manic, G., Signore, M., Sistigu, A., Russo, G., Corradi, F., Siteni, S., Musella, M., Vitale, S., De Angelis, M. L., Pallocca, M., Amoreo, C. A., Sperati, F., Di Franco, S., Barresi, S., Policicchio, E., De Luca, G., De Nicola, F., Mottolese, M., Zeuner, A., Fanciulli, M. & 6 others, Stassi, G., Maugeri-Saccà, M., Baiocchi, M., Tartaglia, M., Vitale, I. & De Maria, R., May 1 2018, In : Gut. 67, 5, p. 903-917 15 p.

Research output: Contribution to journalArticle

CHK1-targeted therapy to deplete DNA replication-stressed, p53-deficient, hyperdiploid colorectal cancer stem cells

Manic, G., Signore, M., Sistigu, A., Russo, G., Corradi, F., Siteni, S., Musella, M., Vitale, S., De Angelis, M. L., Pallocca, M., Amoreo, C. A., Sperati, F., Di Franco, S., Barresi, S., Policicchio, E., De Luca, G., De Nicola, F., Mottolese, M., Zeuner, A., Fanciulli, M. & 6 others, Stassi, G., Maugeri-Saccà, M., Baiocchi, M., Tartaglia, M., Vitale, I. & De Maria, R., Apr 7 2017, In : Gut.

Research output: Contribution to journalArticle

DNA Damage in Stem Cells

Vitale, I., Manic, G., Maria, R. D., Kroemer, G. & Galluzzi, L., May 4 2017, In : Molecular Cell. 66, 3, p. 306-319 14 p.

Research output: Contribution to journalArticle

Macrophages and Metabolism in the Tumor Microenvironment.

Vitale, I., Manic, G., Coussens, L. M., Kroemer, G. & Galluzzi, L., Jul 1 2019, In : Cell Metabolism. 30, p. 36-50 15 p.

Research output: Contribution to journalArticle

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

Galluzzi, L., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., Annicchiarico-Petruzzelli, M., Antonov, A. V., Arama, E., Baehrecke, E. H., Barlev, N. A., Bazan, N. G., Bernassola, F., Bertrand, M. J. M., Bianchi, K., Blagosklonny, M. V. & 149 others, Blomgren, K., Borner, C., Boya, P., Brenner, C., Campanella, M., Candi, E., Carmona-Gutierrez, D., Cecconi, F., Chan, F. K-M., Chandel, N. S., Cheng, E. H., Chipuk, J. E., Cidlowski, J. A., Ciechanover, A., Cohen, G. M., Conrad, M., Cubillos-Ruiz, J. R., Czabotar, P. E., D'Angiolella, V., Dawson, T. M., Dawson, V. L., De Laurenzi, V., De Maria, R., Debatin, K-M., DeBerardinis, R. J., Deshmukh, M., Di Daniele, N., Di Virgilio, F., Dixit, V. M., Dixon, S. J., Duckett, C. S., Dynlacht, B. D., El-Deiry, W. S., Elrod, J. W., Fimia, G. M., Fulda, S., García-Sáez, A. J., Garg, A. D., Garrido, C., Gavathiotis, E., Golstein, P., Gottlieb, E., Green, D. R., Greene, L. A., Gronemeyer, H., Gross, A., Hajnoczky, G., Hardwick, J. M., Harris, I. S., Hengartner, M. O., Hetz, C., Ichijo, H., Jäättelä, M., Joseph, B., Jost, P. J., Juin, P. P., Kaiser, W. J., Karin, M., Kaufmann, T., Kepp, O., Kimchi, A., Kitsis, R. N., Klionsky, D. J., Knight, R. A., Kumar, S., Lee, S. W., Lemasters, J. J., Levine, B., Linkermann, A., Lipton, S. A., Lockshin, R. A., López-Otín, C., Lowe, S. W., Luedde, T., Lugli, E., MacFarlane, M., Madeo, F., Malewicz, M., Malorni, W., Manic, G., Marine, J-C., Martin, S. J., Martinou, J-C., Medema, J. P., Mehlen, P., Meier, P., Melino, S., Miao, E. A., Molkentin, J. D., Moll, U. M., Muñoz-Pinedo, C., Nagata, S., Nuñez, G., Oberst, A., Oren, M., Overholtzer, M., Pagano, M., Panaretakis, T., Pasparakis, M., Penninger, J. M., Pereira, D. M., Pervaiz, S., Peter, M. E., Piacentini, M., Pinton, P., Prehn, J. H. M., Puthalakath, H., Rabinovich, G. A., Rehm, M., Rizzuto, R., Rodrigues, C. M. P., Rubinsztein, D. C., Rudel, T., Ryan, K. M., Sayan, E., Scorrano, L., Shao, F., Shi, Y., Silke, J., Simon, H-U., Sistigu, A., Stockwell, B. R., Strasser, A., Szabadkai, G., Tait, S. W. G., Tang, D., Tavernarakis, N., Thorburn, A., Tsujimoto, Y., Turk, B., Vanden Berghe, T., Vandenabeele, P., Vander Heiden, M. G., Villunger, A., Virgin, H. W., Vousden, K. H., Vucic, D., Wagner, E. F., Walczak, H., Wallach, D., Wang, Y., Wells, J. A., Wood, W., Yuan, J., Zakeri, Z., Zhivotovsky, B., Zitvogel, L., Melino, G. & Kroemer, G., Mar 2018, In : Cell Death and Differentiation. 25, 3, p. 486-541 56 p.

Research output: Contribution to journalArticle

Molecular mechanisms of cell death: Recommendations of the Nomenclature Committee on Cell Death 2018

Galluzzi, L., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., Annicchiarico-Petruzzelli, M., Antonov, A. V., Arama, E., Baehrecke, E. H., Barlev, N. A., Bazan, N. G., Bernassola, F., Bertrand, M. J. M., Bianchi, K., Blagosklonny, M. V. & 30 others, Blomgren, K., Borner, C., Boya, P., Brenner, C., Campanella, M., Candi, E., Carmona-Gutierrez, D., Cecconi, F., Chan, FK-M., Chandel, N. S., Cheng, E. H., Chipuk, J. E., Cidlowski, J. A., Ciechanover, A., Cohen, G. M., Conrad, M., Cubillos-Ruiz, J. R., Czabotar, P. E., D'Angiolella, V., Dawson, T. M., De Maria, R., Fimia, G. M., Lugli, E., Malorni, W., Manic, G., Pagano, M., Piacentini, M., Sistigu, A., Tait, S. W. G. & Melino, G., 2018, In : Cell Death and Differentiation. 25, 3, p. 486-541 56 p.

Research output: Contribution to journalArticle

Molecular Regulation of the Spindle Assembly Checkpoint by Kinases and Phosphatases

Manic, G., Corradi, F., Sistigu, A., Siteni, S. & Vitale, I., 2017, In : International Review of Cell and Molecular Biology. 328, p. 105-161 57 p.

Research output: Contribution to journalArticle

Replication stress in colorectal cancer stem cells

Manic, G., Maria, R. D. & Vitale, I., Jun 7 2017, In : Oncotarget. 8, 53, p. 90606-90607

Research output: Contribution to journalArticle

Trial watch - inhibiting PARP enzymes for anticancer therapy

Sistigu, A., Manic, G., Obrist, F. & Vitale, I., Mar 2016, In : Molecular & cellular oncology. 3, 2, p. e1053594

Research output: Contribution to journalArticle

Type-I-interferons in infection and cancer: Unanticipated dynamics with therapeutic implications

Musella, M., Manic, G., Maria, R. D., Vitale, I. & Sistigu, A., 2017, In : OncoImmunology. 6, 5, p. e1314424

Research output: Contribution to journalArticle

Whole-genome duplication increases tumor cell sensitivity to MPS1 inhibition

Jemaà, M., Manic, G., Lledo, G., Lissa, D., Reynes, C., Morin, N., Chibon, F., Sistigu, A., Castedo, M., Vitale, I., Kroemer, G. & Abrieu, A., Jan 5 2016, In : Oncotarget. 7, 1, p. 885-901 17 p.

Research output: Contribution to journalArticle

Chapter

Assessment of IFN-γ and granzyme-B production by in “sitro” technology

Galassi, C., Manic, G., Musella, M., Sistigu, A. & Vitale, I., Jan 1 2019, (Accepted/In press) Methods in Enzymology. Academic Press Inc., (Methods in Enzymology).

Research output: Chapter in Book/Report/Conference proceedingChapter

Cytofluorometric assessment of dendritic cell-mediated uptake of cancer cell apoptotic bodies

Musella, M., Manic, G., Galassi, C., Vitale, I. & Sistigu, A., Jan 1 2019, (Accepted/In press) Methods in Enzymology. Academic Press Inc., (Methods in Enzymology).

Research output: Chapter in Book/Report/Conference proceedingChapter

Review article

Macrophages and Metabolism in the Tumor Microenvironment

Vitale, I., Manic, G., Coussens, L. M., Kroemer, G. & Galluzzi, L., Jul 2 2019, In : Cell Metabolism. 30, 1, p. 36-50 15 p.

Research output: Contribution to journalReview article

Open Access

Molecular mechanisms of cell death: Recommendations of the Nomenclature Committee on Cell Death 2018

Galluzzi, L., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., Annicchiarico-Petruzzelli, M., Antonov, A. V., Arama, E., Baehrecke, E. H., Barlev, N. A., Bazan, N. G., Bernassola, F., Bertrand, M. J. M., Bianchi, K., Blagosklonny, M. V. & 149 others, Blomgren, K., Borner, C., Boya, P., Brenner, C., Campanella, M., Candi, E., Carmona-Gutierrez, D., Cecconi, F., Chan, F. K. M., Chandel, N. S., Cheng, E. H., Chipuk, J. E., Cidlowski, J. A., Ciechanover, A., Cohen, G. M., Conrad, M., Cubillos-Ruiz, J. R., Czabotar, P. E., D'Angiolella, V., Dawson, T. M., Dawson, V. L., De Laurenzi, V., De Maria, R., Debatin, K. M., Deberardinis, R. J., Deshmukh, M., Di Daniele, N., Di Virgilio, F., Dixit, V. M., Dixon, S. J., Duckett, C. S., Dynlacht, B. D., El-Deiry, W. S., Elrod, J. W., Fimia, G. M., Fulda, S., García-Sáez, A. J., Garg, A. D., Garrido, C., Gavathiotis, E., Golstein, P., Gottlieb, E., Green, D. R., Greene, L. A., Gronemeyer, H., Gross, A., Hajnoczky, G., Hardwick, J. M., Harris, I. S., Hengartner, M. O., Hetz, C., Ichijo, H., Jäättelä, M., Joseph, B., Jost, P. J., Juin, P. P., Kaiser, W. J., Karin, M., Kaufmann, T., Kepp, O., Kimchi, A., Kitsis, R. N., Klionsky, D. J., Knight, R. A., Kumar, S., Lee, S. W., Lemasters, J. J., Levine, B., Linkermann, A., Lipton, S. A., Lockshin, R. A., López-Otín, C., Lowe, S. W., Luedde, T., Lugli, E., MacFarlane, M., Madeo, F., Malewicz, M., Malorni, W., Manic, G., Marine, J. C., Martin, S. J., Martinou, J. C., Medema, J. P., Mehlen, P., Meier, P., Melino, S., Miao, E. A., Molkentin, J. D., Moll, U. M., Muñoz-Pinedo, C., Nagata, S., Nuñez, G., Oberst, A., Oren, M., Overholtzer, M., Pagano, M., Panaretakis, T., Pasparakis, M., Penninger, J. M., Pereira, D. M., Pervaiz, S., Peter, M. E., Piacentini, M., Pinton, P., Prehn, J. H. M., Puthalakath, H., Rabinovich, G. A., Rehm, M., Rizzuto, R., Rodrigues, C. M. P., Rubinsztein, D. C., Rudel, T., Ryan, K. M., Sayan, E., Scorrano, L., Shao, F., Shi, Y., Silke, J., Simon, H. U., Sistigu, A., Stockwell, B. R., Strasser, A., Szabadkai, G., Tait, S. W. G., Tang, D., Tavernarakis, N., Thorburn, A., Tsujimoto, Y., Turk, B., Vanden Berghe, T., Vandenabeele, P., Vander Heiden, M. G., Villunger, A., Virgin, H. W., Vousden, K. H., Vucic, D., Wagner, E. F., Walczak, H., Wallach, D., Wang, Y., Wells, J. A., Wood, W., Yuan, J., Zakeri, Z., Zhivotovsky, B., Zitvogel, L., Melino, G. & Kroemer, G., Mar 1 2018, In : Cell Death and Differentiation. 25, 3, p. 486-541 56 p.

Research output: Contribution to journalReview article

Mutational and Antigenic Landscape in Tumor Progression and Cancer Immunotherapy

Vitale, I., Sistigu, A., Manic, G., Rudqvist, N. P., Trajanoski, Z. & Galluzzi, L., May 2019, In : Trends in Cell Biology. 29, 5, p. 396-416 21 p.

Research output: Contribution to journalReview article

Replication stress response in cancer stem cells as a target for chemotherapy

Manic, G., Sistigu, A., Corradi, F., Musella, M., De Maria, R. & Vitale, I., Dec 1 2018, In : Seminars in Cancer Biology. 53, p. 31-41 11 p.

Research output: Contribution to journalReview article

Stress responses in stromal cells and tumor homeostasis

Vitale, I., Manic, G., Galassi, C. & Galluzzi, L., Aug 2019, In : Pharmacology and Therapeutics. 200, p. 55-68 14 p.

Research output: Contribution to journalReview article