1992 …2019

Research output per year

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Research Output

2019
2018

Microenvironmental regulation of the IL-23R/IL-23 axis overrides chronic lymphocytic leukemia indolence

Cutrona, G., Tripodo, C., Matis, S., Recchia, A. G., Massucco, C., Fabbi, M., Colombo, M., Emionite, L., Sangaletti, S., Gulino, A., Reverberi, D., Massara, R., Boccardo, S., de Totero, D., Salvi, S., Cilli, M., Pellicanò, M., Manzoni, M., Fabris, S., Airoldi, I. & 16 others, Valdora, F., Ferrini, S., Gentile, M., Vigna, E., Bossio, S., De Stefano, L., Palummo, A., Iaquinta, G., Cardillo, M., Zupo, S., Cerruti, G., Ibatici, A., Neri, A., Fais, F., Ferrarini, M. & Morabito, F., Feb 14 2018, In : Science Translational Medicine. 10, 428

Research output: Contribution to journalArticle

Microenvironmental regulation of the IL-23R/IL-23 axis overrides chronic lymphocytic leukemia indolence

Cutrona, G., Tripodo, C., Matis, S., Recchia, A. G., Massucco, C., Fabbi, M., Colombo, M., Emionite, L., Sangaletti, S., Gulino, A., Reverberi, D., Massara, R., Boccardo, S., De Totero, D., Salvi, S., Cilli, M., Pellicanò, M., Manzoni, M., Fabris, S., Airoldi, I. & 16 others, Valdora, F., Ferrini, S., Gentile, M., Vigna, E., Bossio, S., De Stefano, L., Palummo, A., Iaquinta, G., Cardillo, M., Zupo, S., Cerruti, G., Ibatici, A., Neri, A., Fais, F., Ferrarini, M. & Morabito, F., 2018, In : Science Translational Medicine. 10, 428

Research output: Contribution to journalArticle

Microenvironmental regulation of the IL-23R/IL-23 axis overrides chronic lymphocytic leukemia indolence

Cutrona, G., Tripodo, C., Matis, S., Recchia, A. G., Massucco, C., Fabbi, M., Colombo, M., Emionite, L., Sangaletti, S., Gulino, A., Reverberi, D., Massara, R., Boccardo, S., De Totero, D., Salvi, S., Cilli, M., Pellicanò, M., Manzoni, M., Fabris, S., Airoldi, I. & 16 others, Valdora, F., Ferrini, S., Gentile, M., Vigna, E., Bossio, S., De Stefano, L., Palummo, A., Iaquinta, G., Cardillo, M., Zupo, S., Cerruti, G., Ibatici, A., Neri, A., Fais, F., Ferrarini, M. & Morabito, F., 2018, In : Science Translational Medicine. 10, 428

Research output: Contribution to journalArticle

Microenvironmental regulation of the IL-23R/IL-23 axis overrides chronic lymphocytic leukemia indolence

Cutrona, G., Tripodo, C., Matis, S., Recchia, A. G., Massucco, C., Fabbi, M., Colombo, M., Emionite, L., Sangaletti, S., Gulino, A., Reverberi, D., Massara, R., Boccardo, S., De Totero, D., Salvi, S., Cilli, M., Pellicanò, M., Manzoni, M., Fabris, S., Airoldi, I. & 16 others, Valdora, F., Ferrini, S., Gentile, M., Vigna, E., Bossio, S., De Stefano, L., Palummo, A., Iaquinta, G., Cardillo, M., Zupo, S., Cerruti, G., Ibatici, A., Neri, A., Fais, F., Ferrarini, M. & Morabito, F., Feb 14 2018, In : Science Translational Medicine. 10, 428, eaal1571.

Research output: Contribution to journalArticle

2017

EphA3 targeting reduces in vitro adhesion and invasion and in vivo growth and angiogenesis of multiple myeloma cells

la Rocca, F., Airoldi, I., Di Carlo, E., Marotta, P., Falco, G., Simeon, V., Laurenzana, I., Trino, S., de Luca, L., Todoerti, K., Villani, O., Lackmann, M., D’Auria, F., Frassoni, F., Neri, A., Del Vecchio, L., Musto, P., Cilloni, D. & Caivano, A., 2017, In : Cellular Oncology. 40, 5, p. 483-496 14 p.

Research output: Contribution to journalArticle

EphA3 targeting reduces in vitro adhesion and invasion and in vivo growth and angiogenesis of multiple myeloma cells

La Rocca, F., Airoldi, I., Di Carlo, E., Marotta, P., Falco, G., Simeon, V., Laurenzana, I., Trino, S., De Luca, L., Todoerti, K., Villani, O., Lackmann, M., D’Auria, F., Frassoni, F., Neri, A., Del Vecchio, L., Musto, P., Cilloni, D. & Caivano, A., 2017, In : Cellular Oncology. 40, 5, p. 483-496 14 p.

Research output: Contribution to journalArticle

EphA3 targeting reduces in vitro adhesion and invasion and in vivo growth and angiogenesis of multiple myeloma cells

La Rocca, F., Airoldi, I., Di Carlo, E., Marotta, P., Falco, G., Simeon, V., Laurenzana, I., Trino, S., De Luca, L., Todoerti, K., Villani, O., Lackmann, M., D'Auria, F., Frassoni, F., Neri, A., Del Vecchio, L., Musto, P., Cilloni, D. & Caivano, A., Oct 2017, In : Cellular oncology (Dordrecht). 40, 5, p. 483-496 14 p.

Research output: Contribution to journalArticle

Zoledronic acid boosts γδ T-cell activity in children receiving αβ+ T and CD19+ cell-depleted grafts from an HLA-haplo-identical donor

Bertaina, A., Zorzoli, A., Petretto, A., Barbarito, G., Inglese, E., Merli, P., Lavarello, C., Brescia, L. P., De Angelis, B., Tripodi, G., Moretta, L., Locatelli, F. & Airoldi, I., 2017, In : OncoImmunology. 6, 2, p. e1216291

Research output: Contribution to journalArticle

2016

Dependence on glutamine uptake and glutamine addiction characterize myeloma cells: A new attractive target

Bolzoni, M., Chiu, M., Accardi, F., Vescovini, R., Airoldi, I., Storti, P., Todoerti, K., Agnelli, L., Missale, G., Andreoli, R., Bianchi, M. G., Allegri, M., Barilli, A., Nicolini, F., Cavalli, A., Costa, F., Marchica, V., Toscani, D., Mancini, C., Martella, E. & 5 others, Dall'Asta, V., Donofrio, G., Aversa, F., Bussolati, O. & Giuliani, N., 2016, In : Blood. 128, 5, p. 667-679 13 p.

Research output: Contribution to journalArticle

Dependence on glutamine uptake and glutamine addiction characterize myeloma cells: A new attractive target

Bolzoni, M., Chiu, M., Accardi, F., Vescovini, R., Airoldi, I., Storti, P., Todoerti, K., Agnelli, L., Missale, G., Andreoli, R., Bianchi, M. G., Allegri, M., Barilli, A., Nicolini, F., Cavalli, A., Costa, F., Marchica, V., Toscani, D., Mancini, C., Martella, E. & 5 others, Dall'Asta, V., Donofrio, G., Aversa, F., Bussolati, O. & Giuliani, N., 2016, In : Blood. 128, 5, p. 667-679 13 p.

Research output: Contribution to journalArticle

Dependence on glutamine uptake and glutamine addiction characterize myeloma cells: A new attractive target

Bolzoni, M., Chiu, M., Accardi, F., Vescovini, R., Airoldi, I., Storti, P., Todoerti, K., Agnelli, L., Missale, G., Andreoli, R., Bianchi, M. G., Allegri, M., Barilli, A., Nicolini, F., Cavalli, A., Costa, F., Marchica, V., Toscani, D., Mancini, C., Martella, E. & 5 others, Dall'Asta, V., Donofrio, G., Aversa, F., Bussolati, O. & Giuliani, N., 2016, In : Blood. 128, 5, p. 667-679 13 p.

Research output: Contribution to journalArticle

Galectin-1 suppression delineates a new strategy to inhibit myeloma-induced angiogenesis and tumoral growth in vivo

Storti, P., Marchica, V., Airoldi, I., Donofrio, G., Fiorini, E., Ferri, V., Guasco, D., Todoerti, K., Silbermann, R., Anderson, J., Zhao, W., Agnelli, L., Bolzoni, M., Martella, E., Mancini, C., Campanini, N., Noonan, D. M., Petronini, P. G., Neri, A., Aversa, F. & 2 others, Roodman, G. D. & Giuliani, N., Jun 17 2016, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

Galectin-1 suppression delineates a new strategy to inhibit myeloma-induced angiogenesis and tumoral growth in vivo

Storti, P., Marchica, V., Airoldi, I., Donofrio, G., Fiorini, E., Ferri, V., Guasco, D., Todoerti, K., Silbermann, R., Anderson, J., Zhao, W., Agnelli, L., Bolzoni, M., Martella, E., Mancini, C., Campanini, N., Noonan, D. M., Petronini, P. G., Neri, A., Aversa, F. & 2 others, Roodman, G. D. & Giuliani, N., 2016, In : Leukemia. 30, 12, p. 2351-2363 13 p.

Research output: Contribution to journalArticle

Galectin-1 suppression delineates a new strategy to inhibit myeloma-induced angiogenesis and tumoral growth in vivo

Storti, P., Marchica, V., Airoldi, I., Donofrio, G., Fiorini, E., Ferri, V., Guasco, D., Todoerti, K., Silbermann, R., Anderson, J. L., Zhao, W., Agnelli, L., Bolzoni, M., Martella, E., Mancini, C., Campanini, N., Noonan, D. M., Petronini, P. G., Neri, A., Aversa, F. & 2 others, Roodman, G. D. & Giuliani, N., Jun 17 2016, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

IL12RB2 Polymorphisms correlate with risk of lung adenocarcinoma

Prigione, I., Covone, A. E. L., Giacopelli, F., Bocca, P., Risso, F. M., Tripodi, G., Pistorio, A., Sozzi, G., Airoldi, I., Ravazzolo, R. & Pistoia, V., Feb 1 2016, In : Immunobiology. 221, 2, p. 291-299 9 p.

Research output: Contribution to journalArticle

IL12RB2 Polymorphisms correlate with risk of lung adenocarcinoma

Prigione, I., Covone, A. E., Giacopelli, F., Bocca, P., Risso, M., Tripodi, G., Pistorio, A., Sozzi, G., Airoldi, I., Ravazzolo, R. & Pistoia, V., Feb 1 2016, In : Immunobiology. 221, 2, p. 291-299 9 p.

Research output: Contribution to journalArticle

Interleukin-30 promotes breast cancer growth and progression

Airoldi, I., Cocco, C., Sorrentino, C., Angelucci, D., Di Meo, S., Manzoli, L., Esposito, S., Ribatti, D., Bertolotto, M., Iezzi, L., Natoli, C. & Di Carlo, E., Nov 1 2016, In : Cancer Research. 76, 21, p. 6218-6229 12 p.

Research output: Contribution to journalArticle

SOX2 boosts major tumor progression genes in prostate cancer and is a functional biomarker of lymph node metastasis

Russo, M. V., Esposito, S., Tupone, M. G., Manzoli, L., Airoldi, I., Pompa, P., Cindolo, L., Schips, L., Sorrentino, C. & Di Carlo, E., Mar 15 2016, In : Oncotarget. 7, 11, p. 12372-12385 14 p.

Research output: Contribution to journalArticle

The anti-tumoral effect of lenalidomide is increased in vivo by hypoxia-inducible factor (HIF)-1α inhibition in myeloma cells

Storti, P., Toscani, D., Airoldi, I., Marchica, V., Maiga, S., Bolzoni, M., Fiorini, E., Campanini, N., Martella, E., Mancini, C., Guasco, D., Ferri, V., Donofrio, G., Aversa, F., Amiot, M. & Giuliani, N., 2016, In : Haematologica. 101, 3, p. e107-e110

Research output: Contribution to journalArticle

2015

IL-27 induces the expression of IDO and PD-L1 in human cancer cells

Carbotti, G., Barisione, G., Airoldi, I., Mezzanzanica, D., Bagnoli, M., Ferrero, S., Petretto, A., Fabbi, M. & Ferrini, S., 2015, In : Oncotarget. 6, 41, p. 43267-43280 14 p.

Research output: Contribution to journalArticle

Interleukin-27 re-educates intratumoral myeloid cells and down-regulates stemness genes in non-small cell lung cancer

Airoldi, I., Tupone, M. G., Esposito, S., Russo, M. V., Barbarito, G., Cipollone, G. & Di Carlo, E., 2015, In : Oncotarget. 6, 6, p. 3694-3708 15 p.

Research output: Contribution to journalArticle

SNAI2/Slug gene is silenced in prostate cancer and regulates neuroendocrine differentiation, metastasis-suppressor and pluripotency gene expression

Esposito, S., Russo, M. V., Airoldi, I., Tupone, M. G., Sorrentino, C., Barbarito, G., Meo, S. D. & Carlo, E. D., 2015, In : Oncotarget. 6, 19, p. 17121-17134 14 p.

Research output: Contribution to journalArticle

γδ T-cell reconstitution after HLA-haploidentical hematopoietic transplantation depleted of TCR-αβ+/CD19+ lymphocytes

Airoldi, I., Bertaina, A., Prigione, I., Zorzoli, A., Pagliara, D., Cocco, C., Meazza, R., Loiacono, F., Lucarelli, B., Bernardo, M. E., Barbarito, G., Pende, D., Moretta, A., Pistoia, V., Moretta, L. & Locatelli, F., Apr 9 2015, In : Blood. 125, 15, p. 2349-2358 10 p.

Research output: Contribution to journalArticle

2014

Erratum: The IL-12rβ2 gene functions as a tumor suppressor in human B cell malignancies (Journal of Clinical Investigation (2004) 113:11 (1651-1659) DOI: 10.1172/JCI20303)

Airoldi, I., Di Carlo, E., Banelli, B., Moserle, L., Cocco, C., Pezzolo, A., Sorrentino, C., Rossi, E., Romani, M., Amadori, A. & Pistoia, V., Jun 2 2014, In : Journal of Clinical Investigation. 124, 6, p. 2807 1 p.

Research output: Contribution to journalArticle

IL-27 in human secondary lymphoid organs attracts myeloid dendritic cells and impairs HLA class I-restricted antigen presentation

Morandi, F., Di Carlo, E., Ferrone, S., Petretto, A., Pistoia, V. & Airoldi, I., Mar 15 2014, In : Journal of Immunology. 192, 6, p. 2634-2642 9 p.

Research output: Contribution to journalArticle

Interleukin-30 expression in prostate cancer and its draining lymph nodes correlates with advanced grade and stage

Di Meo, S., Airoldi, I., Sorrentino, C., Zorzoli, A., Esposito, S. & Di Carlo, E., 2014, In : Clinical Cancer Research. 20, 3, p. 585-594 10 p.

Research output: Contribution to journalArticle

The antitumor potential of Interleukin-27 in prostate cancer

Di Carlo, E., Sorrentino, C., Zorzoli, A., Di Meo, S., Tupone, M. G., Ognio, E., Mincione, G. & Airoldi, I., 2014, In : Oncotarget. 5, 21, p. 10332-10341 10 p.

Research output: Contribution to journalArticle

2013

Hypoxia-inducible factor (HIF)-1α suppression in myeloma cells blocks tumoral growth in vivo inhibiting angiogenesis and bone destruction

Storti, P., Bolzoni, M., Donofrio, G., Airoldi, I., Guasco, D., Toscani, D., Martella, E., Lazzaretti, M., Mancini, C., Agnelli, L., Patrene, K., Maïga, S., Franceschi, V., Colla, S., Anderson, J., Neri, A., Amiot, M., Aversa, F., David Roodman, G. & Giuliani, N., Aug 2013, In : Leukemia. 27, 8, p. 1697-1706 10 p.

Research output: Contribution to journalArticle

The IL-18 antagonist IL-18-binding protein is produced in the human ovarian cancer microenvironment

Carbotti, G., Barisione, G., Orengo, A. M., Brizzolara, A., Airoldi, I., Bagnoli, M., Pinciroli, P., Mezzanzanica, D., Centurioni, M. G., Fabbi, M. & Ferrini, S., Sep 1 2013, In : Clinical Cancer Research. 19, 17, p. 4611-4620 10 p.

Research output: Contribution to journalArticle

2012

Absence of IL-12RΒ2 in CD33 + CD38 + pediatric acute myeloid leukemia cells favours progression in NOD/SCID/IL2RγC- deficient mice

Ferretti, E., Montagna, D., Di Carlo, E., Cocco, C., Ribatti, D., Ognio, E., Sorrentino, C., Lisini, D., Bertaina, A., Locatelli, F., Pistoia, V. & Airoldi, I., Feb 2012, In : Leukemia. 26, 2, p. 225-235 11 p.

Research output: Contribution to journalArticle

Complementary IL-23 and IL-27 anti-tumor activities cause strong inhibition of human follicular and diffuse large B-cell lymphoma growth in vivo

Cocco, C., Di Carlo, E., Zupo, S., Canale, S., Zorzoli, A., Ribatti, D., Morandi, F., Ognio, E. & Airoldi, I., Jun 2012, In : Leukemia. 26, 6, p. 1365-1374 10 p.

Research output: Contribution to journalArticle

Human TCRγδ + T cells represent a novel target for IL-27 activity

Morandi, F., Prigione, I. & Airoldi, I., Jun 2012, In : European Journal of Immunology. 42, 6, p. 1547-1552 6 p.

Research output: Contribution to journalArticle

Interleukin-27 inhibits the growth of pediatric acute myeloid leukemia in NOD/SCID/Il2rg -/- mice

Zorzoli, A., Di Carlo, E., Cocco, C., Ognio, E., Ribatti, D., Ferretti, E., Dufour, C., Locatelli, F., Montagna, D. & Airoldi, I., Mar 15 2012, In : Clinical Cancer Research. 18, 6, p. 1630-1640 11 p.

Research output: Contribution to journalArticle

Mda-9/syntenin is expressed in uveal melanoma and correlates with metastatic progression

Gangemi, R., Mirisola, V., Barisione, G., Fabbi, M., Brizzolara, A., Lanza, F., Mosci, C., Salvi, S., Gualco, M., Truini, M., Angelini, G., Boccardo, S., Cilli, M., Airoldi, I., Queirolo, P., Jager, M. J., Daga, A., Pfeffer, U. & Ferrini, S., Jan 13 2012, In : PLoS One. 7, 1, e29989.

Research output: Contribution to journalArticle

Research Highlights: Highlights from the latest articles in immunomodulation

Cocco, C. & Airoldi, I., Jul 2012, In : Immunotherapy. 4, 7, p. 667-668 2 p.

Research output: Contribution to journalArticle

Targeting acute myeloid leukemia cells with cytokines

Ferretti, E., Cocco, C., Airoldi, I. & Pistoia, V., Sep 2012, In : Journal of Leukocyte Biology. 92, 3, p. 567-575 9 p.

Research output: Contribution to journalArticle

2011

Cytokines and microRNA in pediatric B-acute lymphoblastic leukemia

Cocco, C. & Airoldi, I., Jun 2011, In : Cytokine and Growth Factor Reviews. 22, 3, p. 149-156 8 p.

Research output: Contribution to journalArticle

Cytokines as anti-angiogenic agents in haematological malignancies

Cocco, C., Ferretti, E., Airoldi, I. & Pistoia, V., Nov 2011, In : Current Cancer Drug Targets. 11, 9, p. 997-1004 8 p.

Research output: Contribution to journalArticle

HOXB7 expression by myeloma cells regulates their pro-angiogenic properties in multiple myeloma patients

Storti, P., Donofrio, G., Colla, S., Airoldi, I., Bolzoni, M., Agnelli, L., Abeltino, M., Todoerti, K., Lazzaretti, M., Mancini, C., Ribatti, D., Bonomini, S., Franceschi, V., Pistoia, V., Lisignoli, G., Pedrazzini, A., Cavicchi, O., Neri, A., Rizzoli, V. & Giuliani, N., Mar 2011, In : Leukemia. 25, 3, p. 527-537 11 p.

Research output: Contribution to journalArticle

Interleukin-27 and interleukin-23 modulate human plasmacell functions

Cocco, C., Morandi, F. & Airoldi, I., May 2011, In : Journal of Leukocyte Biology. 89, 5, p. 729-734 6 p.

Research output: Contribution to journalArticle

Interleukin-27 inhibits pediatric B-acute lymphoblastic leukemia cell spreading in a preclinical model

Canale, S., Cocco, C., Frasson, C., Seganfreddo, E., Di Carlo, E., Ognio, E., Sorrentino, C., Ribatti, D., Zorzoli, A., Basso, G., Dufour, C. & Airoldi, I., Dec 2011, In : Leukemia. 25, 12, p. 1815-1824 10 p.

Research output: Contribution to journalArticle

Novel insights into the role of interleukin-27 and interleukin-23 in human malignant and normal plasma cells

Giuliani, N. & Airoldi, I., Nov 15 2011, In : Clinical Cancer Research. 17, 22, p. 6963-6970 8 p.

Research output: Contribution to journalArticle

Regulation of angiostatic chemokines driven by IL-12 and IL-27 in human tumors

Airoldi, I. & Ribatti, D., Nov 2011, In : Journal of Leukocyte Biology. 90, 5, p. 875-882 8 p.

Research output: Contribution to journalArticle

2010

Direct inhibition of human acute myeloid leukemia cell growth by IL-12

Ferretti, E., Di Carlo, E., Cocco, C., Ribatti, D., Sorrentino, C., Ognio, E., Montagna, D., Pistoia, V. & Airoldi, I., Oct 2010, In : Immunology Letters. 133, 2, p. 99-105 7 p.

Research output: Contribution to journalArticle