• 68 Citations
  • 5 h-Index
20082016
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Fingerprint Dive into the research topics where Lara Fontani is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 3 Similar Profiles
Antibodies Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Immunoglobulin Fragments Medicine & Life Sciences
Active Immunotherapy Medicine & Life Sciences
Tropism Medicine & Life Sciences
Genetic Therapy Medicine & Life Sciences
Neoplastic Stem Cells Medicine & Life Sciences
Half-Life Medicine & Life Sciences

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Research Output 2008 2016

  • 68 Citations
  • 5 h-Index
  • 6 Article

Cardiac concentric hypertrophy promoted by activated Met receptor is mitigated in vivo by inhibition of Erk1,2 signalling with Pimasertib

Sala, V., Gallo, S., Gatti, S., Medico, E., Vigna, E., Cantarella, D., Fontani, L., Natale, M., Cimino, J., Morello, M., Comoglio, P. M., Ponzetto, A. & Crepaldi, T., Apr 1 2016, In : Journal of Molecular and Cellular Cardiology. 93, p. 84-97 14 p.

Research output: Contribution to journalArticle

Cardiomegaly
Heart Failure
Natriuretic Peptides
Cytoskeletal Proteins
Hepatocyte Growth Factor
7 Citations (Scopus)

Dual Constant Domain-Fab: A novel strategy to improve half-life and potency of a Met therapeutic antibody

Cignetto, S., Modica, C., Chiriaco, C., Fontani, L., Milla, P., Michieli, P., Comoglio, P. M. & Vigna, E., Jun 1 2016, In : Molecular Oncology. 10, 6, p. 938-948 11 p.

Research output: Contribution to journalArticle

Half-Life
Antibodies
Neoplasms
Molecular Weight
Immunoglobulin Fab Fragments
7 Citations (Scopus)

Inhibition of ligand-independent constitutive activation of the Met oncogenic receptor by the engineered chemically-modified antibody DN30

Vigna, E., Chiriaco, C., Cignetto, S., Fontani, L., Basilico, C., Petronzelli, F. & Comoglio, P. M., Nov 1 2015, In : Molecular Oncology. 9, 9, p. 1760-1772 13 p.

Research output: Contribution to journalArticle

Ligands
Antibodies
Hepatocyte Growth Factor
Growth
Immunoglobulin Fragments
6 Citations (Scopus)

Targeted therapy by gene transfer of a monovalent antibody fragment against the Met oncogenic receptor

Vigna, E., Pacchiana, G., Chiriaco, C., Cignetto, S., Fontani, L., Michieli, P. & Comoglio, P. M., Jan 2014, In : Journal of Molecular Medicine. 92, 1, p. 65-76 12 p.

Research output: Contribution to journalArticle

Immunoglobulin Fragments
Genetic Therapy
Neoplasms
Immunoglobulin Fab Fragments
Glioblastoma
22 Citations (Scopus)

Primary breast cancer stem-like cells metastasise to bone, switch phenotype and acquire a bone tropism signature

D'Amico, L., Patanè, S., Grange, C., Bussolati, B., Isella, C., Fontani, L., Godio, L., Cilli, M., D'Amelio, P., Isaia, G., Medico, E., Ferracini, R. & Roato, I., Jun 25 2013, In : British Journal of Cancer. 108, 12, p. 2525-2536 12 p.

Research output: Contribution to journalArticle

Tropism
Neoplastic Stem Cells
Breast Neoplasms
Phenotype
Bone and Bones