• 567 Citations
  • 14 h-Index
20052018
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Research Output 2005 2018

  • 567 Citations
  • 14 h-Index
  • 18 Article
  • 1 Chapter
  • 1 Review article
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Article
2018
3 Citations (Scopus)

MRCKα is activated by caspase cleavage to assemble an apical actin ring for epithelial cell extrusion

Gagliardi, P. A., Somale, D., Puliafito, A., Chiaverina, G., di Blasio, L., Oneto, M., Bianchini, P., Bussolino, F. & Primo, L., Jan 1 2018, In : Journal of Cell Biology. 217, 1, p. 231-249 19 p.

Research output: Contribution to journalArticle

Myotonic Dystrophy
Caspases
Actins
Phosphotransferases
Epithelial Cells
15 Citations (Scopus)
Vascular Malformations
Phosphatidylinositol 3-Kinases
Endothelial Cells
Mutation
Klippel-Trenaunay-Weber Syndrome
2017
2 Citations (Scopus)

The AGMA1 polyamidoamine mediates the efficient delivery of siRNA

Cavalli, R., Primo, L., Sessa, R., Chiaverina, G., di Blasio, L., Alongi, J., Manfredi, A., Ranucci, E. & Ferruti, P., Nov 26 2017, In : Journal of Drug Targeting. 25, 9-10, p. 891-898 8 p.

Research output: Contribution to journalArticle

Small Interfering RNA
Transfection
Guanidine
Gene Silencing
HeLa Cells
2016

Dasatinib modulates sensitivity to pemetrexed in malignant pleural mesothelioma cell lines

Monica, V., Lo Iacono, M., Bracco, E., Busso, S., Di Blasio, L., Primo, L., Peracino, B., Papotti, M. & Vittorio Scagliotti, G., 2016, In : Oncotarget.

Research output: Contribution to journalArticle

2015
46 Citations (Scopus)

PDK1: A signaling hub for cell migration and tumor invasion

Gagliardi, P. A., di Blasio, L. & Primo, L., Dec 1 2015, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1856, 2, p. 178-188 11 p.

Research output: Contribution to journalArticle

Cell Movement
Neoplasms
Aptitude
Transducers
Physiological Phenomena
14 Citations (Scopus)

PDK1 regulates focal adhesion disassembly by modulating endocytosis of αvβ3 integrin

di Blasio, L., Gagliardi, P. A., Puliafito, A., Sessa, R., Seano, G., Bussolino, F. & Primo, L., 2015, In : Journal of Cell Science. 128, 5, p. 863-877 15 p.

Research output: Contribution to journalArticle

Focal Adhesions
Phosphatidylinositols
Endocytosis
Integrins
Protein Kinases
14 Citations (Scopus)

Real-time monitoring of cell protrusion dynamics by impedance responses

Gagliardi, P. A., Puliafito, A., Di Blasio, L., Chianale, F., Somale, D., Seano, G., Bussolino, F. & Primo, L., May 15 2015, In : Scientific Reports. 5, 10206.

Research output: Contribution to journalArticle

Electric Impedance
Intercellular Signaling Peptides and Proteins
Myosins
Microscopy
Cell Surface Extensions
2 Citations (Scopus)
Morphogenesis
Endothelial Cells
Gels
Blood Vessels
Pathologic Neovascularization
2014
64 Citations (Scopus)

Endothelial podosome rosettes regulate vascular branching in tumour angiogenesis

Seano, G., Chiaverina, G., Gagliardi, P. A., Di Blasio, L., Puliafito, A., Bouvard, C., Sessa, R., Tarone, G., Sorokin, L., Helley, D., Jain, R. K., Serini, G., Bussolino, F. & Primo, L., Jan 1 2014, In : Nature Cell Biology. 16, 10, p. 931-941 11 p.

Research output: Contribution to journalArticle

Blood Vessels
Integrins
Neoplasms
Basement Membrane
Pathologic Neovascularization
44 Citations (Scopus)

Gelatin-based hydrogel for vascular endothelial growth factor release in peripheral nerve tissue engineering

Gnavi, S., di Blasio, L., Tonda-Turo, C., Mancardi, A., Primo, L., Ciardelli, G., Gambarotta, G., Geuna, S. & Perroteau, I., 2014, (Accepted/In press) In : Journal of Tissue Engineering and Regenerative Medicine.

Research output: Contribution to journalArticle

Nerve Tissue
Hydrogel
Gelatin
Tissue Engineering
Peripheral Nerves
21 Citations (Scopus)

PDK1-mediated activation of MRCKα regulates directional cell migration and lamellipodia retraction

Gagliardi, P. A., di Blasio, L., Puliafito, A., Seano, G., Sessa, R., Chianale, F., Leung, T., Bussolino, F. & Primo, L., 2014, In : Journal of Cell Biology. 206, 3, p. 415-434 20 p.

Research output: Contribution to journalArticle

Myotonic Dystrophy
Pseudopodia
1-Phosphatidylinositol 4-Kinase
Cell Movement
Phosphotransferases
2013
44 Citations (Scopus)

Modeling human tumor angiogenesis in a three-dimensional culture system.

Seano, G., Chiaverina, G., Gagliardi, P. A., di Blasio, L., Sessa, R., Bussolino, F. & Primo, L., May 23 2013, In : Blood. 121, 21

Research output: Contribution to journalArticle

Tumors
Assays
Neoplasms
Endothelial cells
Blood Vessels
2012
38 Citations (Scopus)

3-Phosphoinositide-dependent kinase 1 controls breast tumor growth in a kinase-dependent but Akt-independent manner

Gagliardi, P. A., di Blasio, L., Orso, F., Seano, G., Sessa, R., Taverna, D., Bussolino, F. & Primo, L., Aug 2012, In : Neoplasia (United States). 14, 8, p. 719-731 13 p.

Research output: Contribution to journalArticle

3-Phosphoinositide-Dependent Protein Kinases
Phosphotransferases
Breast Neoplasms
Growth
Phosphatidylinositol 3-Kinase
53 Citations (Scopus)

The miR-126 regulates Angiopoietin-1 signaling and vessel maturation by targeting p85β

Sessa, R., Seano, G., di Blasio, L., Gagliardi, P. A., Isella, C., Medico, E., Cotelli, F., Bussolino, F. & Primo, L., Oct 2012, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1823, 10, p. 1925-1935 11 p.

Research output: Contribution to journalArticle

Angiopoietin-1
Blood Vessels
Vascular Endothelial Growth Factor A
Class Ia Phosphatidylinositol 3-Kinase
Endothelial Cells
2010
33 Citations (Scopus)

Increased expression of α6 integrin in endothelial cells unveils a proangiogenic role for basement membrane

Primo, L., Seano, G., Roca, C., Maione, F., Gagliardi, P. A., Sessa, R., Martinelli, M., Giraudo, E., Di Blasio, L. & Bussolino, F., Jul 15 2010, In : Cancer Research. 70, 14, p. 5759-5769 11 p.

Research output: Contribution to journalArticle

Basement Membrane
Integrins
Endothelial Cells
Fibroblast Growth Factor 2
Vascular Endothelial Growth Factor A
32 Citations (Scopus)

Protein kinase D1 regulates VEGF-A-induced αvβ3 integrin trafficking and endothelial cell migration

di Blasio, L., Droetto, S., Norman, J., Bussolino, F. & Primo, L., Aug 2010, In : Traffic. 11, 8, p. 1107-1118 12 p.

Research output: Contribution to journalArticle

Endothelial cells
Integrins
Protein Kinases
Vascular Endothelial Growth Factor A
Cell Movement
2007
59 Citations (Scopus)

Essential role of PDK1 in regulating endothelial cell migration

Primo, L., Di Blasio, L., Roca, C., Droetto, S., Piva, R., Schaffhausen, B. & Bussolino, F., Mar 26 2007, In : Journal of Cell Biology. 176, 7, p. 1035-1047 13 p.

Research output: Contribution to journalArticle

1-Phosphatidylinositol 4-Kinase
Cell Movement
Endothelial Cells
Chemotaxis
Vascular Endothelial Growth Factor A
2005
63 Citations (Scopus)

Identification of CD36 molecular features required for its in vitro angiostatic activity

Primo, L., Ferrandi, C., Roca, C., Marchio, S., Di Blasio, L., Alessio, M. & Bussolino, F., Oct 2005, In : FASEB Journal. 19, 12, p. 1713-1715 3 p.

Research output: Contribution to journalArticle