20092019

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2019

Combination of Immunotherapy and Brain Radiotherapy in Metastatic Melanoma: A Retrospective Analysis

Galli, G., Cavalieri, S., Di Guardo, L., Cimminiello, C., Nichetti, F., Corti, F., Garcia, M. A., Pappalardi, B., Fallai, C., De Braud, F., Platania, M. & Del Vecchio, M., Apr 1 2019, In : Oncology Research and Treatment. 42, 4, p. 182-188 7 p.

Research output: Contribution to journalArticle

Developing a score system to predict therapeutic outcomes to anti-PD-1 immunotherapy in metastatic melanoma

Indini, A., Di Guardo, L., Cimminiello, C., Prisciandaro, M., Randon, G., De Braud, F. & Del Vecchio, M., Jan 1 2019, (Accepted/In press) In : Tumori.

Research output: Contribution to journalArticle

Immune-related adverse events correlate with improved survival in patients undergoing anti-PD1 immunotherapy for metastatic melanoma

Indini, A., Di Guardo, L., Cimminiello, C., Prisciandaro, M., Randon, G., De Braud, F. & Del Vecchio, M., Feb 13 2019, In : Journal of Cancer Research and Clinical Oncology. 145, 2, p. 511-521 11 p.

Research output: Contribution to journalArticle

Open Access

Pembrolizumab in the treatment of advanced/metastatic melanoma: A single-center institution experience

Cimminiello, C., Indini, A., Di Guardo, L., Prisciandaro, M., Randon, G., Tolomio, E., De Braud, F. & Del Vecchio, M., Jun 1 2019, In : Melanoma Research. 29, 3, p. 289-294 6 p.

Research output: Contribution to journalArticle

The density and spatial tissue distribution of CD8+ and CD163+ immune cells predict response and outcome in melanoma patients receiving MAPK inhibitors

Intergroup, I. M., Massi, D., Rulli, E., Cossa, M., Valeri, B., Rodolfo, M., Merelli, B., De Logu, F., Nassini, R., Del Vecchio, M., Di Guardo, L., De Penni, R., Guida, M., Sileni, V. C., Di Giacomo, A. M., Tucci, M., Occelli, M., Portelli, F., Vallacchi, V., Consoli, F. & 9 others, Quaglino, P., Queirolo, P., Baroni, G., Carnevale-Schianca, F., Cattaneo, L., Minisini, A., Palmieri, G., Rivoltini, L. & Mandalà, M., Nov 15 2019, In : Journal for ImmunoTherapy of Cancer. 7, 1, p. 1-13 13 p., 308.

Research output: Contribution to journalArticle

The density and spatial tissue distribution of CD8+ and CD163+ immune cells predict response and outcome in melanoma patients receiving MAPK inhibitors

Massi, D., Rulli, E., Cossa, M., Valeri, B., Rodolfo, M., Merelli, B., De Logu, F., Nassini, R., Del Vecchio, M., Di Guardo, L., De Penni, R., Guida, M., Sileni, V. C., Di Giacomo, A. M., Tucci, M., Occelli, M., Portelli, F., Vallacchi, V., Consoli, F., Quaglino, P. & 10 others, Queirolo, P., Baroni, G., Carnevale-Schianca, F., Cattaneo, L., Minisini, A., Palmieri, G., Rivoltini, L., Mandalà, M., Simi, S. & Galli, F., 2019, In : Journal for ImmunoTherapy of Cancer. 7, 1

Research output: Contribution to journalArticle

2018

Current status and perspectives in immunotherapy for metastatic melanoma

Marconcini, R., Spagnolo, F., Stucci, L. S., Ribero, S., Marra, E., de Rosa, F. D., Picasso, V., di Guardo, L. D., Cimminiello, C., Cavalieri, S., Orgiano, L., Tanda, E., Spano, L., Falcone, A., Queirolo, P., Palmieri, G., Stanganelli, I., Mandalà, M., Quaglino, P., Botti, G. & 3 others, Caracò, C., Sileni, V. C. & di Giacomo, A. M., 2018, In : Oncotarget. 9, 15, p. 12452-12470 19 p.

Research output: Contribution to journalArticle

Current status and perspectives in immunotherapy for metastatic melanoma

Marconcini, R., Spagnolo, F., Stucci, L. S., Ribero, S., Marra, E., de Rosa, F. D., Picasso, V., di Guardo, L. D., Cimminiello, C., Cavalieri, S., Orgiano, L., Tanda, E., Spano, L., Falcone, A., Queirolo, P., Palmieri, G., Stanganelli, I., Mandalà, M., Quaglino, P., Botti, G. & 3 others, Caracò, C., Sileni, V. C. & di Giacomo, A. M., Jan 1 2018, In : Oncotarget. 9, 15, p. 12452-12470 19 p.

Research output: Contribution to journalArticle

Tumor-derived microRNAs induce myeloid suppressor cells and predict immunotherapy resistance in melanoma

Huber, V., Vallacchi, V., Fleming, V., Hu, X., Cova, A., Dugo, M., Shahaj, E., Sulsenti, R., Vergani, E., Filipazzi, P., De Laurentiis, A., Lalli, L., Di Guardo, L., Patuzzo, R., Vergani, B., Casiraghi, E., Cossa, M., Gualeni, A., Bollati, V., Arienti, F. & 7 others, De Braud, F., Mariani, L., Villa, A., Altevogt, P., Umansky, V., Rodolfo, M. & Rivoltini, L., Dec 3 2018, In : Journal of Clinical Investigation. 128, 12, p. 5505-5516 12 p.

Research output: Contribution to journalArticle

2017

Clinical features of serous retinopathy observed with cobimetinib in patients with BRAF-mutated melanoma treated in the randomized coBRIM study

de la Cruz-Merino, L., Di Guardo, L., Grob, J-J., Venosa, A., Larkin, J., McArthur, G. A., Ribas, A., Ascierto, P. A., Evans, J. T. R., Gomez-Escobar, A., Barteselli, G., Eng, S., Hsu, J. J., Uyei, A. & Dréno, B., Jun 24 2017, In : Journal of Translational Medicine. 15, 1, p. 146

Research output: Contribution to journalArticle

2016

CARAMEL study: Clinical prognostic biomarkers for ipilimumab-related outcome in metastatic melanoma patients

Orgiano, L., Bruder, F., Madeddu, C., Marconcini, R., Gambale, E., Galizia, E., Stucci, S., Spagnolo, F., Di Guardo, L., Loi, C., Pani, F., Massa, D., Massa, E., Astara, G., Del Vecchio, M., Silvestris, F., de tursi, M., Falcone, A., Queirolo, P. & Scartozzi, M., Oct 1 2016, In : Annals of Oncology. 27, p. vi386

Research output: Contribution to journalArticle

Open Access

Combined therapy with dabrafenib and trametinib in BRAF-mutated metastatic melanoma in a real-life setting: The INT Milan experience

Cavalieri, S., Di Guardo, L., Cimminiello, C., Bono, A., Tolomio, E., Colombetti, A., Valeri, B., Di Tolla, G., De Braud, F. & Del Vecchio, M., Sep 1 2016, In : Tumori. 102, 5, p. 501-507 7 p.

Research output: Contribution to journalArticle

Overcoming melanoma resistance to vemurafenib by targeting CCL2-induced miR-34a, miR-100 and miR-125b

Vergani, E., Di Guardo, L., Dugo, M., Rigoletto, S., Tragni, G., Ruggeri, R., Perrone, F., Tamborini, E., Gloghini, A., Arienti, F., Vergani, B., Deho, P., De Cecco, L., Vallacchi, V., Frati, P., Shahaj, E., Villa, A., Santinami, M., De Braud, F., Rivoltini, L. & 1 others, Rodolfo, M., 2016, In : Oncotarget. 7, 4, p. 4428-4441 14 p.

Research output: Contribution to journalArticle

2015
2014

Clinical experience with ipilimumab 3 mg/kg: Real-world efficacy and safety data from an expanded access programme cohort

Ascierto, P. A., Simeone, E., Sileni, V. C., Pigozzo, J., Maio, M., Altomonte, M., Del Vecchio, M., Di Guardo, L., Marchetti, P., Ridolfi, R., Cognetti, F., Testori, A., Bernengo, M. G., Guida, M., Marconcini, R., Mandalà, M., Cimminiello, C., Rinaldi, G., Aglietta, M. & Queirolo, P., May 7 2014, In : Journal of Translational Medicine. 12, 1, 116.

Research output: Contribution to journalArticle

Efficacy and safety of ipilimumab 3 mg/kg in patients with pretreated, metastatic, mucosal melanoma

Del Vecchio, M., Di Guardo, L., Ascierto, P. A., Grimaldi, A. M., Sileni, V. C., Pigozzo, J., Ferraresi, V., Nuzzo, C., Rinaldi, G., Testori, A., Ferrucci, P. F., Marchetti, P., De Galitiis, F., Queirolo, P., Tornari, E., Marconcini, R., Calabrò, L. & Maio, M., Jan 2014, In : European Journal of Cancer. 50, 1, p. 121-127 7 p.

Research output: Contribution to journalArticle

Efficacy and safety of ipilimumab in elderly patients with pretreated advanced melanoma treated at Italian centres through the expanded access programme

Sileni, V. C., Pigozzo, J., Ascierto, P. A., Grimaldi, A. M., Maio, M., Di Guardo, L., Marchetti, P., De Rosa, F., Nuzzo, C., Testori, A., Cocorocchio, E., Bernengo, M. G., Guida, M., Marconcini, R., Merelli, B., Parmiani, G., Rinaldi, G., Aglietta, M., Grosso, M. & Queirolo, P., Apr 4 2014, In : Journal of Experimental and Clinical Cancer Research. 33, 1, 30.

Research output: Contribution to journalArticle

Efficacy and safety of ipilimumab in patients with advanced melanoma and brain metastases

Queirolo, P., Spagnolo, F., Ascierto, P. A., Simeone, E., Marchetti, P., Scoppola, A., Del Vecchio, M., Di Guardo, L., Maio, M., Di Giacomo, A. M., Antonuzzo, A., Cognetti, F., Ferraresi, V., Ridolfi, L., Guidoboni, M., Guida, M., Pigozzo, J. & Chiarion Sileni, V., 2014, In : Journal of Neuro-Oncology. 118, 1, p. 109-116 8 p.

Research output: Contribution to journalArticle

Ipilimumab retreatment in patients with pretreated advanced melanoma: The expanded access programme in Italy

Chiarion-Sileni, V., Pigozzo, J., Ascierto, P. A., Simeone, E., Maio, M., Calabrò, L., Marchetti, P., De Galitiis, F., Testori, A., Ferrucci, P. F., Queirolo, P., Spagnolo, F., Quaglino, P., Carnevale Schianca, F., Mandalà, M., Di Guardo, L. & Del Vecchio, M., Apr 1 2014, In : British Journal of Cancer. 110, 7, p. 1721-1726 6 p.

Research output: Contribution to journalArticle

2013

Efficacy and safety of ipilimumab in patients with pre-treated, uveal melanoma

Maio, M., Danielli, R., Chiarion-Sileni, V., Pigozzo, J., Parmiani, G., Ridolfi, R., De Rosa, F., Del Vecchio, M., Di Guardo, L., Queirolo, P., Picasso, V., Marchetti, P., De Galitiis, F., Mandalà, M., Guida, M., Simeone, E. & Ascierto, P. A., Nov 2013, In : Annals of Oncology. 24, 11, p. 2911-2915 5 p., mdt376.

Research output: Contribution to journalArticle

2011

T-cell activation and maturation at tumor site associated with objective response to ipilimumab in metastatic melanoma

Del Vecchio, M., Mortarini, R., Tragni, G., Di Guardo, L., Bersani, I., Di Tolla, G., Agustoni, F., Colonna, V., Weber, J. S. & Anichini, A., Nov 10 2011, In : Journal of Clinical Oncology. 29, 32

Research output: Contribution to journalArticle

2010

Bevacizumab plus fotemustine as first-line treatment in metastatic melanoma patients: Clinical activity and modulation of angiogenesis and lymphangiogenesis factors

Del Vecchio, M., Mortarini, R., Canova, S., Di Guardo, L., Pimpinelli, N., Sertoli, M. R., Bedognetti, D., Queirolo, P., Morosini, P., Perrone, T., Bajetta, E. & Anichini, A., Dec 1 2010, In : Clinical Cancer Research. 16, 23, p. 5862-5872 11 p.

Research output: Contribution to journalArticle

2009

Pitfalls in the diagnosis of neuroendocrine tumors: Atypical clinical and radiological findings as cause of medical mistakes

Bajetta, E., Catena, L., Ducceschi, M., Pusceddu, S., Milione, M., Maccauro, M., Bajetta, R., Procopio, G., Buzzoni, R., Formisano, B., Di Guardo, L. & Platania, M., 2009, In : Tumori. 95, 4, p. 501-507 7 p.

Research output: Contribution to journalArticle