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Research Output 2017 2019

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Article
2019

Bronchial epithelium repair by Esculentin-1a-derived antimicrobial peptides: involvement of metalloproteinase-9 and interleukin-8, and evaluation of peptides' immunogenicity

Cappiello, F., Ranieri, D., Carnicelli, V., Casciaro, B., Chen, H-T., Ferrera, L., Di, Y. P. & Mangoni, M. L., Dec 12 2019, In : Scientific Reports. 9, 1, p. 18988

Research output: Contribution to journalArticle

Metalloproteases
Interleukin-8
Epithelium
Peptides
Wound Healing

Lumacaftor-rescued F508del-CFTR has a modified bicarbonate permeability

Ferrera, L., Baroni, D. & Moran, O., Sep 2019, In : Journal of Cystic Fibrosis. 18, 5, p. 602-605 4 p.

Research output: Contribution to journalArticle

Bicarbonates
Permeability
Phenylalanine
Cystic Fibrosis
Anions
2018

Pharmacological Inhibition of the Ubiquitin Ligase RNF5 Rescues F508del-CFTR in Cystic Fibrosis Airway Epithelia

Sondo, E., Falchi, F., Caci, E., Ferrera, L., Giacomini, E., Pesce, E., Tomati, V., Mandrup Bertozzi, S., Goldoni, L., Armirotti, A., Ravazzolo, R., Cavalli, A. & Pedemonte, N., Jul 19 2018, In : Cell Chemical Biology. 25, 7, p. 891-905.e8

Research output: Contribution to journalArticle

Ligases
Ubiquitin
Cystic Fibrosis
Epithelium
Pharmacology

The Autophagy Inhibitor Spautin-1 Antagonizes Rescue of Mutant CFTR Through an Autophagy-Independent and USP13-Mediated Mechanism

Pesce, E., Sondo, E., Ferrera, L., Tomati, V., Caci, E., Scudieri, P., Musante, I., Renda, M., Baatallah, N., Servel, N., Hinzpeter, A., di Bernardo, D., Pedemonte, N. & Galietta, L. J. V., 2018, In : Frontiers in Pharmacology. 9, p. 1464

Research output: Contribution to journalArticle

Autophagy
Cystic Fibrosis
Biological Phenomena
Chloride Channels
Quality Control
2017

Phenylquinoxalinone CFTR activator as potential prosecretory therapy for constipation

Cil, O., Phuan, P-W., Son, J-H., Zhu, J. S., Ku, C. K., Tabib, N. A., Teuthorn, A. P., Ferrera, L., Zachos, N. C., Lin, R., Galietta, L. J. V., Donowitz, M., Kurth, M. J. & Verkman, A. S., Apr 2017, In : Translational Research. 182, p. 14-26.e4

Research output: Contribution to journalArticle

Cystic Fibrosis Transmembrane Conductance Regulator
Constipation
Intestinal Secretions
Fluids and Secretions
Fluids

Substituted 2-Acylaminocycloalkylthiophene-3-carboxylic Acid Arylamides as Inhibitors of the Calcium-Activated Chloride Channel Transmembrane Protein 16A (TMEM16A)

Truong, E. C., Phuan, P. W., Reggi, A. L., Ferrera, L., Galietta, L. J. V., Levy, S. E., Moises, A. C., Cil, O., Diez-Cecilia, E., Lee, S., Verkman, A. S. & Anderson, M. O., Jun 8 2017, In : Journal of Medicinal Chemistry. 60, 11, p. 4626-4635 10 p.

Research output: Contribution to journalArticle

Chloride Channels
Carboxylic Acids
Thiophenes
Proteins
Fluids and Secretions