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Research Output 1993 2019

2019

Cd28 autonomous signaling up‐regulates c‐myc expression and promotes glycolysis enabling inflammatory t cell responses in multiple sclerosis

Kunk, M., Sambucci, M., Ruggieri, S., Amormino, C., Tortorella, C., Gasperini, C., Battistini, L. & Tuosto, L., Jun 2 2019, In : International Journal of Molecular Sciences. 20, 12, 2926.

Research output: Contribution to journalArticle

Open Access
glycolysis
T-cells
Glycolysis
Multiple Sclerosis
Up-Regulation

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

Cossarizza, A., Chang, H. D., Radbruch, A., Acs, A., Adam, D., Adam-Klages, S., Agace, W. W., Aghaeepour, N., Akdis, M., Allez, M., Almeida, L. N., Alvisi, G., Anderson, G., Andrä, I., Annunziato, F., Anselmo, A., Bacher, P., Baldari, C. T., Bari, S., Barnaba, V. & 30 others, Barros-Martins, J., Battistini, L., Bauer, W., Baumgart, S., Baumgarth, N., Baumjohann, D., Baying, B., Bebawy, M., Becher, B., Beisker, W., Benes, V., Beyaert, R., Borsellino, G., Cavani, A., Clerici, M., Colombo, F. S., Del Zotto, G., Della Bella, S., Dellabona, P., Gori, A., Lugli, E., Mantovani, A., Marventano, I., Matarese, G., Moretta, L., Piancone, F., Rubartelli, A., Santoni, A., Saresella, M. & Sozzani, S., Oct 1 2019, In : European Journal of Immunology. 49, 10, p. 1457-1973 517 p.

Research output: Contribution to journalArticle

Flow Cytometry
Guidelines
Allergy and Immunology
Phenotype
Research

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

Cossarizza, A., Chang, H. D., Radbruch, A., Acs, A., Adam, D., Adam-Klages, S., Agace, W. W., Aghaeepour, N., Akdis, M., Allez, M., Almeida, L. N., Alvisi, G., Anderson, G., Andrä, I., Annunziato, F., Anselmo, A., Bacher, P., Baldari, C. T., Bari, S., Barnaba, V. & 30 others, Barros-Martins, J., Battistini, L., Bauer, W., Baumgart, S., Baumgarth, N., Baumjohann, D., Baying, B., Bebawy, M., Becher, B., Beisker, W., Benes, V., Beyaert, R., Borsellino, G., Cavani, A., Clerici, M., Colombo, F. S., Del Zotto, G., Della Bella, S., Dellabona, P., Gori, A., Lugli, E., Mantovani, A., Marventano, I., Matarese, G., Moretta, L., Piancone, F., Rubartelli, A., Santoni, A., Saresella, M. & Sozzani, S., Oct 1 2019, In : European Journal of Immunology. 49, 10, p. 1457-1973 517 p.

Research output: Contribution to journalArticle

Flow Cytometry
Guidelines
Allergy and Immunology
Phenotype
Research

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

Cossarizza, A., Chang, H. D., Radbruch, A., Acs, A., Adam, D., Adam-Klages, S., Agace, W. W., Aghaeepour, N., Akdis, M., Allez, M., Almeida, L. N., Alvisi, G., Anderson, G., Andrä, I., Annunziato, F., Anselmo, A., Bacher, P., Baldari, C. T., Bari, S., Barnaba, V. & 30 others, Barros-Martins, J., Battistini, L., Bauer, W., Baumgart, S., Baumgarth, N., Baumjohann, D., Baying, B., Bebawy, M., Becher, B., Beisker, W., Benes, V., Beyaert, R., Borsellino, G., Cavani, A., Clerici, M., Colombo, F. S., Del Zotto, G., Della Bella, S., Dellabona, P., Gori, A., Lugli, E., Mantovani, A., Marventano, I., Matarese, G., Moretta, L., Piancone, F., Rubartelli, A., Santoni, A., Saresella, M. & Sozzani, S., Oct 1 2019, In : European Journal of Immunology. 49, 10, p. 1457-1973 517 p.

Research output: Contribution to journalArticle

Human primary macrophages scavenge AuNPs and eliminate it through exosomes. A natural shuttling for nanomaterials

Logozzi, M., Mizzoni, D., Bocca, B., Di Raimo, R., Petrucci, F., Caimi, S., Alimonti, A., Falchi, M., Cappello, F., Campanella, C., Bavisotto, C. C., David, S., Bucchieri, F., Angelini, D. F., Battistini, L. & Fais, S., Apr 1 2019, In : European Journal of Pharmaceutics and Biopharmaceutics. 137, p. 23-36 14 p.

Research output: Contribution to journalArticle

Exosomes
Nanostructures
Macrophages
Nanoparticles
Endocytosis

Increased plasmatic levels of psa-expressing exosomes distinguish prostate cancer patients from benign prostatic hyperplasia: A prospective study

Logozzi, M., Angelini, D. F., Giuliani, A., Mizzoni, D., Raimo, R. D., Maggi, M., Gentilucci, A., Marzio, V., Salciccia, S., Borsellino, G., Battistini, L., Sciarra, A. & Fais, S., Oct 1 2019, In : Cancers. 11, 10, 1449.

Research output: Contribution to journalArticle

Open Access
Exosomes
Prostatic Hyperplasia
Prostatic Neoplasms
Prospective Studies
Prostate-Specific Antigen

Natural killer cells protect white matter integrity in bipolar disorder

Furlan, R., Melloni, E., Finardi, A., Vai, B., Di Toro, S., Aggio, V., Battistini, L., Borsellino, G., Manfredi, E., Falini, A., Colombo, C., Poletti, S. & Benedetti, F., Jan 1 2019, In : Brain, Behavior, and Immunity.

Research output: Contribution to journalArticle

Bipolar Disorder
Lithium
Natural Killer Cells
Anisotropy
Magnetic Resonance Imaging
Open Access
Regulatory T-Lymphocytes
Autoimmunity
Multiple Sclerosis
Lymphocyte Subsets
Transcriptome

Resiquimod-Mediated Activation of Plasmacytoid Dendritic Cells Is Amplified in Multiple Sclerosis

Corsetti, M., Ruocco, G., Ruggieri, S., Gasperini, C., Battistini, L. & Volpe, E., Jun 8 2019, In : International Journal of Molecular Sciences. 20, 11

Research output: Contribution to journalArticle

Open Access
resiquimod
Dendritic Cells
Multiple Sclerosis
Chemical activation
activation

Running-Activated Neural Stem Cells Enhance Subventricular Neurogenesis and Improve Olfactory Behavior in p21 Knockout Mice

Nicolis di Robilant, V., Scardigli, R., Strimpakos, G., Tirone, F., Middei, S., Scopa, C., De Bardi, M., Battistini, L., Saraulli, D. & Farioli Vecchioli, S., Jan 1 2019, In : Molecular Neurobiology.

Research output: Contribution to journalArticle

Neural Stem Cells
Lateral Ventricles
Neurogenesis
Knockout Mice
Running
2018

AMBRA1 Controls Regulatory T-Cell Differentiation and Homeostasis Upstream of the FOXO3-FOXP3 Axis

Becher, J., Simula, L., Volpe, E., Procaccini, C., La Rocca, C., D'Acunzo, P., Cianfanelli, V., Strappazzon, F., Caruana, I., Nazio, F., Weber, G., Gigantino, V., Botti, G., Ciccosanti, F., Borsellino, G., Campello, S., Mandolesi, G., De Bardi, M., Fimia, G. M., D'Amelio, M. & 11 others, Ruffini, F., Furlan, R., Centonze, D., Martino, G., Braghetta, P., Chrisam, M., Bonaldo, P., Matarese, G., Locatelli, F., Battistini, L. & Cecconi, F., Dec 3 2018, In : Developmental Cell. 47, 5, p. 592-607 15 p.

Research output: Contribution to journalArticle

T-cells
Regulatory T-Lymphocytes
Cell Differentiation
Homeostasis
Complex networks

AMBRA1 Controls Regulatory T-Cell Differentiation and Homeostasis Upstream of the FOXO3-FOXP3 Axis

Becher, J., Simula, L., Volpe, E., Procaccini, C., La Rocca, C., D'Acunzo, P., Cianfanelli, V., Strappazzon, F., Caruana, I., Nazio, F., Weber, G., Gigantino, V., Botti, G., Ciccosanti, F., Borsellino, G., Campello, S., Mandolesi, G., De Bardi, M., Fimia, G. M., D'Amelio, M. & 11 others, Ruffini, F., Furlan, R., Centonze, D., Martino, G., Braghetta, P., Chrisam, M., Bonaldo, P., Matarese, G., Locatelli, F., Battistini, L. & Cecconi, F., 2018, In : Developmental Cell. 47, 5, p. 592-607.e6

Research output: Contribution to journalArticle

AMBRA1 Controls Regulatory T-Cell Differentiation and Homeostasis Upstream of the FOXO3-FOXP3 Axis

Becher, J., Simula, L., Volpe, E., Procaccini, C., La Rocca, C., D'Acunzo, P., Cianfanelli, V., Strappazzon, F., Caruana, I., Nazio, F., Weber, G., Gigantino, V., Botti, G., Ciccosanti, F., Borsellino, G., Campello, S., Mandolesi, G., De Bardi, M., Fimia, G. M., D'Amelio, M. & 11 others, Ruffini, F., Furlan, R., Centonze, D., Martino, G., Braghetta, P., Chrisam, M., Bonaldo, P., Matarese, G., Locatelli, F., Battistini, L. & Cecconi, F., Dec 3 2018, In : Developmental Cell. p. 592-607 16 p.

Research output: Contribution to journalArticle

T-cells
Regulatory T-Lymphocytes
Cell Differentiation
Homeostasis
Disease Susceptibility

Analysis of coding and non-coding transcriptome of peripheral B cells reveals an altered interferon response factor (IRF)-1 pathway in multiple sclerosis patients

Annibali, V., Umeton, R., Palermo, A., Severa, M., Etna, M. P., Giglio, S., Romano, S., Ferraldeschi, M., Buscarinu, M. C., Vecchione, A., Annese, A., Policano, C., Mechelli, R., Pizzolato Umeton, R., Fornasiero, A., Angelini, D. F., Guerrera, G., Battistini, L., Coccia, E. M., Salvetti, M. & 1 others, Ristori, G., Nov 15 2018, In : Journal of Neuroimmunology. 324, p. 165-171 7 p.

Research output: Contribution to journalArticle

Transcriptome
Interferons
Multiple Sclerosis
B-Lymphocytes
Down-Regulation

FoxP3 isoforms and PD-1 expression by T regulatory cells in multiple sclerosis

Sambucci, M., Gargano, F., De Rosa, V., De Bardi, M., Picozza, M., Placido, R., Ruggieri, S., Capone, A., Gasperini, C., Matarese, G., Battistini, L. & Borsellino, G., Dec 1 2018, In : Scientific Reports. 8, 1, 3674.

Research output: Contribution to journalArticle

Regulatory T-Lymphocytes
Multiple Sclerosis
Protein Isoforms
Autoimmune Diseases
Homeostasis

Longitudinal detection of DNMT3AR882H transcripts in patients with acute myeloid leukemia

Ottone, T., Alfonso, V., Iaccarino, L., Hasan, S. K., Mancini, M., Divona, M., Lavorgna, S., Cicconi, L., Panetta, P., Maurillo, L., Del Principe, M. I., Irno Consalvo, M., Franceschini, L., Angelini, D. F., Battistini, L., Guerrera, G., De Bardi, M., Fabiani, E., Falconi, G., Arcese, W. & 5 others, Amadori, S., Buccisano, F., Venditti, A., Voso, M. T. & Lo-Coco, F., Jan 1 2018, (Accepted/In press) In : American Journal of Hematology.

Research output: Contribution to journalArticle

Microenvironmental pH and exosome levels interplay in human cancer cell lines of different histotypes

Logozzi, M., Mizzoni, D., Angelini, D. F., Di Raimo, R., Falchi, M., Battistini, L. & Fais, S., Oct 5 2018, In : Cancers. 10, 10

Research output: Contribution to journalArticle

Exosomes
Cell Line
Neoplasms
Osteosarcoma
Tumor Cell Line

The RNA binding protein Sam68 controls T helper 1 differentiation and anti-mycobacterial response through modulation of miR-29

Volpe, E., Cesari, E., Mercatelli, N., Cicconi, R., De Bardi, M., Capone, A., Bonvissuto, D., Fraziano, M., Mattei, M., Battistini, L., Paronetto, M. P. & Sette, C., Jan 1 2018, (Accepted/In press) In : Cell Death and Differentiation.

Research output: Contribution to journalArticle

Th1 Cells
RNA-Binding Proteins
Bacillus
Interferons
T-Lymphocytes
2017

Acridine orange/exosomes increase the delivery and the effectiveness of acridine orange in human melanoma cells: A new prototype for theranostics of tumors

Iessi, E., Logozzi, M., Lugini, L., Azzarito, T., Federici, C., Spugnini, E. P., Mizzoni, D., Di Raimo, R., Angelini, D. F., Battistini, L., Cecchetti, S. & Fais, S., Jan 1 2017, In : Journal of Enzyme Inhibition and Medicinal Chemistry. 32, 1, p. 648-657 10 p.

Research output: Contribution to journalArticle

Exosomes
Acridine Orange
Melanoma
Neoplasms
Theranostic Nanomedicine

Guidelines for the use of flow cytometry and cell sorting in immunological studies

Cossarizza, A., Chang, H-D., Radbruch, A., Akdis, M., Andrae, I., Annunziato, F., Bacher, P., Barnaba, V., Battistini, L., Bauer, W. M., Baumgart, S., Becher, B., Beisker, W., Berek, C., Blanco, A., Borsellino, G., Boulais, P. E., Brinkman, R. R., Buescher, M., Busch, D. H. & 216 others, Bushnell, T. P., Cao, X., Cavani, A., Chattopadhyay, P. K., Cheng, Q., Chow, S., Clerici, M., Cooke, A., Cosma, A., Cosmi, L., Cumano, A., Dang, V. D., Davies, D., De Biasi, S., Del Zotto, G., Della Bella, S., Dellabona, P., Deniz, G., Dessing, M., Diefenbach, A., Di Santo, J., Dieli, F., Dolf, A., Donnenberg, V. S., Doerner, T., Ehrhardt, G. R. A., Endl, E., Engel, P., Engelhardt, B., Esser, C., Everts, B., Dreher, A., Falk, C. S., Fehniger, T. A., Filby, A., Fillatreau, S., Follo, M., Foerster, I., Foster, J., Foulds, G. A., Frenette, P. S., Galbraith, D., Garbi, N., Dolores Garcia-Godoy, M., Geginat, J., Ghoreschi, K., Gibellini, L., Goettlinger, C., Goodyear, C. S., Gori, A., Grogan, J., Gross, M., Gruetzkau, A., Grummitt, D., Hahn, J., Hammer, Q., Hauser, A. E., Haviland, D. L., Hedley, D., Herrera, G., Herrmann, M., Hiepe, F., Holland, T., Hombrink, P., Houston, J. P., Hoyer, B. F., Huang, B., Hunter, C. A., Iannone, A., Jaeck, H-M., Javega, B., Jonjic, S., Juelke, K., Jung, S., Kaiser, T., Kalina, T., Keller, B., Khan, S., Kienhoefer, D., Kroneis, T., Kunkel, D., Kurts, C., Kvistborg, P., Lannigan, J., Lantz, O., Larbi, A., LeibundGut-Landmann, S., Leipold, M. D., Levings, M. K., Litwin, V., Liu, Y., Lohoff, M., Lombardi, G., Lopez, L., Lovett-Racke, A., Lubberts, E., Ludewig, B., Lugli, E., Maecker, H. T., Martrus, G., Matarese, G., Maueroeder, C., McGrath, M., McInnes, I., Mei, H. E., Melchers, F., Melzer, S., Mielenz, D., Mills, K., Mirrer, D., Mjosberg, J., Moore, J., Moran, B., Moretta, A., Moretta, L., Mosmann, T. R., Mueller, S., Muller, W., Munz, C., Multhoff, G., Munoz, L. E., Murphy, K. M., Nakayama, T., Nasi, M., Neudoerfl, C., Nolan, J., Nourshargh, S., O'Connor, J-E., Ouyang, W., Oxenius, A., Palankar, R., Panse, I., Peterson, P., Peth, C., Petriz, J., Philips, D., Pickl, W., Piconese, S., Pinti, M., Pockley, A. G., Podolska, M. J., Pucillo, C., Quataert, S. A., Radstake, T. R. D. J., Rajwa, B., Rebhahn, J. A., Recktenwald, D., Remmerswaal, E. B. M., Rezvani, K., Rico, L. G., Robinson, J. P., Romagnani, C., Rubartelli, A., Ruckert, B., Ruland, J., Sakaguchi, S., Sala-de-Oyanguren, F., Samstag, Y., Sanderson, S., Sawitzki, B., Scheffold, A., Schiemann, M., Schildberg, F., Schimisky, E., Schmid, S. A., Schmitt, S., Schober, K., Schueler, T., Schulz, A. R., Schumacher, T., Scotta, C., Shankey, T. V., Shemer, A., Simon, A-K., Spidlen, J., Stall, A. M., Stark, R., Stehle, C., Stein, M., Steinmetz, T., Stockinger, H., Takahama, Y., Tarnok, A., Tian, Z., Toldi, G., Tornack, J., Traggiai, E., Trotter, J., Ulrich, H., van der Braber, M., van Lier, R. A. W., Veldhoen, M., Vento-Asturias, S., Vieira, P., Voehringer, D., Volk, H-D., von Volkmann, K., Waisman, A., Walker, R., Ward, M. D., Warnatz, K., Warth, S., Watson, J. V., Watzl, C., Wegener, L., Wiedemann, A., Wienands, J., Willimsky, G., Wing, J., Wurst, P., Yu, L., Yue, A., Zhang, Q., Zhao, Y., Ziegler, S. & Zimmermann, J., Oct 1 2017, In : European Journal of Immunology. 47, 10, SI, p. 1584-1797 214 p.

Research output: Contribution to journalArticle

Guidelines for the use of flow cytometry and cell sorting in immunological studies

Cossarizza, A., Chang, H. D., Radbruch, A., Andrä, I., Annunziato, F., Bacher, P., Barnaba, V., Barnaba, V., Battistini, L., Bauer, W. M., Baumgart, S., Becher, B., Beisker, W., Berek, C., Blanco, A., Borsellino, G., Boulais, P. E., Boulais, P. E., Brinkman, R. R., Brinkman, R. R. & 81 others, Büscher, M., Busch, D. H., Busch, D. H., Busch, D. H., Bushnell, T. P., Cao, X., Cao, X., Cao, X., Cavani, A., Chattopadhyay, P. K., Cheng, Q., Chow, S., Clerici, M., Cooke, A., Cosma, A., Cosmi, L., Cumano, A., Dang, V. D., Davies, D., De Biasi, S., Del Zotto, G., Della Bella, S., Della Bella, S., Dellabona, P., Deniz, G., Dessing, M., Diefenbach, A., Di Santo, J., Dieli, F., Dolf, A., Donnenberg, V. S., Dörner, T., Ehrhardt, G. R. A., Endl, E., Engel, P., Engelhardt, B., Esser, C., Everts, B., Falk, C. S., Falk, C. S., Fehniger, T. A., Filby, A., Fillatreau, S., Fillatreau, S., Fillatreau, S., Follo, M., Förster, I., Foster, J., Foulds, G. A., Frenette, P. S., Frenette, P. S., Galbraith, D., Garbi, N., Garbi, N., García-Godoy, M. D., Ghoreschi, K., Gibellini, L., Goettlinger, C., Goodyear, C. S., Gori, A., Grogan, J., Gross, M., Grützkau, A., Grummitt, D., Hahn, J., Hammer, Q., Hauser, A. E., Hauser, A. E., Haviland, D. L., Hedley, D., Herrera, G., Herrmann, M., Hiepe, F., Holland, T., Hombrink, P., Houston, J. P., Hoyer, B. F., Huang, B., et al., Rubartelli, A. & et al., Oct 1 2017, In : European Journal of Immunology. 47, 10, p. 1584-1797 214 p.

Research output: Contribution to journalArticle

Guidelines for the use of flow cytometry and cell sorting in immunological studies

Cossarizza, A., Chang, H. D., Radbruch, A., Andrä, I., Annunziato, F., Bacher, P., Barnaba, V., Battistini, L., Bauer, W. M., Baumgart, S., Becher, B., Beisker, W., Berek, C., Blanco, A., Borsellino, G., Boulais, P. E., Brinkman, R. R., Büscher, M., Busch, D. H., Bushnell, T. P. & 211 others, Cao, X., Cavani, A., Chattopadhyay, P. K., Cheng, Q., Chow, S., Clerici, M., Cooke, A., Cosma, A., Cosmi, L., Cumano, A., Dang, V. D., Davies, D., De Biasi, S., Del Zotto, G., Della Bella, S., Dellabona, P., Deniz, G., Dessing, M., Diefenbach, A., Di Santo, J., Dieli, F., Dolf, A., Donnenberg, V. S., Dörner, T., Ehrhardt, G. R. A., Endl, E., Engel, P., Engelhardt, B., Esser, C., Everts, B., Falk, C. S., Fehniger, T. A., Filby, A., Fillatreau, S., Follo, M., Förster, I., Foster, J., Foulds, G. A., Frenette, P. S., Galbraith, D., Garbi, N., García-Godoy, M. D., Ghoreschi, K., Gibellini, L., Goettlinger, C., Goodyear, C. S., Gori, A., Grogan, J., Gross, M., Grützkau, A., Grummitt, D., Hahn, J., Hammer, Q., Hauser, A. E., Haviland, D. L., Hedley, D., Herrera, G., Herrmann, M., Hiepe, F., Holland, T., Hombrink, P., Houston, J. P., Hoyer, B. F., Huang, B., Hunter, C. A., Iannone, A., Jäck, H. M., Jávega, B., Jonjic, S., Juelke, K., Jung, S., Kaiser, T., Kalina, T., Keller, B., Khan, S., Kienhöfer, D., Kroneis, T., Kunkel, D., Kurts, C., Kvistborg, P., Lannigan, J., Lantz, O., Larbi, A., LeibundGut-Landmann, S., Leipold, M. D., Levings, M. K., Litwin, V., Liu, Y., Lohoff, M., Lombardi, G., Lopez, L., Lovett-Racke, A., Lubberts, E., Ludewig, B., Lugli, E., Maecker, H. T., Martrus, G., Matarese, G., Maueröder, C., McGrath, M., McInnes, I., Mei, H. E., Melchers, F., Melzer, S., Mielenz, D., Mills, K., Mjösberg, J., Moore, J., Moran, B., Moretta, A., Moretta, L., Mosmann, T. R., Müller, S., Müller, W., Münz, C., Multhoff, G., Munoz, L. E., Murphy, K. M., Nakayama, T., Nasi, M., Neudörfl, C., Nolan, J., Nourshargh, S., O'Connor, J. E., Ouyang, W., Oxenius, A., Palankar, R., Panse, I., Peterson, P., Peth, C., Petriz, J., Philips, D., Pickl, W., Piconese, S., Pinti, M., Pockley, A. G., Podolska, M. J., Pucillo, C., Quataert, S. A., Radstake, T. R. D. J., Rajwa, B., Rebhahn, J. A., Recktenwald, D., Remmerswaal, E. B. M., Rezvani, K., Rico, L. G., Robinson, J. P., Romagnani, C., Rubartelli, A., Ruland, J., Sakaguchi, S., Sala-de-Oyanguren, F., Samstag, Y., Sanderson, S., Sawitzki, B., Scheffold, A., Schiemann, M., Schildberg, F., Schimisky, E., Schmid, S. A., Schmitt, S., Schober, K., Schüler, T., Schulz, A. R., Schumacher, T., Scotta, C., Shankey, T. V., Shemer, A., Simon, A. K., Spidlen, J., Stall, A. M., Stark, R., Stehle, C., Stein, M., Steinmetz, T., Stockinger, H., Takahama, Y., Tarnok, A., Tian, Z. G., Toldi, G., Tornack, J., Traggiai, E., Trotter, J., Ulrich, H., van der Braber, M., van Lier, R. A. W., Veldhoen, M., Vento-Asturias, S., Vieira, P., Voehringer, D., Volk, H. D., von Volkmann, K., Waisman, A., Walker, R., Ward, M. D., Warnatz, K., Warth, S., Watson, J. V., Watzl, C., Wegener, L., Wiedemann, A., Wienands, J., Willimsky, G., Wing, J., Wurst, P., Yu, L., Yue, A., Zhang, Q., Zhao, Y., Ziegler, S. & Zimmermann, J., Oct 1 2017, In : European Journal of Immunology. 47, 10, p. 1584-1797 214 p.

Research output: Contribution to journalArticle

Guidelines for the use of flow cytometry and cell sorting in immunological studies

Cossarizza, A., Chang, H-D., Radbruch, A., Akdis, M., Andrä, I., Annunziato, F., Bacher, P., Barnaba, V., Battistini, L., Bauer, W. M., Baumgart, S., Becher, B., Beisker, W., Berek, C., Blanco, A., Borsellino, G., Boulais, P. E., Brinkman, R. R., Büscher, M., Busch, D. H. & 30 others, Bushnell, T. P., Cao, X., Cavani, A., Chattopadhyay, P. K., Cheng, Q., Chow, S., Clerici, M., Cooke, A., Cosma, A., Cosmi, L., Cumano, A., Dang, V. D., Davies, D., De Biasi, S., Del Zotto, G., Della Bella, S., Dellabona, P., Deniz, G., Dessing, M., Diefenbach, A., Di Santo, J., Dieli, F., Dolf, A., Donnenberg, V. S., Dörner, T., Ehrhardt, G. R. A., Lugli, E., Matarese, G., Moretta, L. & Rubartelli, A., Oct 2017, In : European Journal of Immunology. 47, 10, p. 1584-1797 214 p.

Research output: Contribution to journalArticle

Guidelines for the use of flow cytometry and cell sorting in immunological studies

Cossarizza, A., Chang, HD., Radbruch, A., Akdis, M., Andrä, I., Annunziato, F., Bacher, P., Barnaba, V., Battistini, L., Bauer, WM., Baumgart, S., Becher, B., Beisker, W., Berek, C., Blanco, A., Borsellino, G., Boulais, PE., Brinkman, RR., Büscher, M., Busch, DH. & 216 others, Bushnell, TP., Cao, X., Cavani, A., Chattopadhyay, PK., Cheng, Q., Chow, S., Clerici, M., Cooke, A., Cosma, A., Cosmi, L., Cumano, A., Dang, VD., Davies, D., De Biasi, S., Del Zotto, G., Della Bella, S., Dellabona, P., Deniz, G., Dessing, M., Diefenbach, A., Di Santo, J., Dieli, F., Dolf, A., Donnenberg, VS., Dörner, T., Ehrhardt, GRA., Endl, E., Engel, P., Engelhardt, B., Esser, C., Everts, B., Dreher, A., Falk, CS., Fehniger, TA., Filby, A., Fillatreau, S., Follo, M., Förster, I., Foster, J., Foulds, GA., Frenette, PS., Galbraith, D., Garbi, N., García-Godoy, MD., Geginat, J., Ghoreschi, K., Gibellini, L., Goettlinger, C., Goodyear, CS., Gori, A., Grogan, J., Gross, M., Grützkau, A., Grummitt, D., Hahn, J., Hammer, Q., Hauser, AE., Haviland, DL., Hedley, D., Herrera, G., Herrmann, M., Hiepe, F., Holland, T., Hombrink, P., Houston, JP., Hoyer, BF., Huang, B., Hunter, CA., Iannone, A., Jäck, HM., Jávega, B., Jonjic, S., Juelke, K., Jung, S., Kaiser, T., Kalina, T., Keller, B., Khan, S., Kienhöfer, D., Kroneis, T., Kunkel, D., Kurts, C., Kvistborg, P., Lannigan, J., Lantz, O., Larbi, A., LeibundGut-Landmann, S., Leipold, MD., Levings, MK., Litwin, V., Liu, Y., Lohoff, M., Lombardi, G., Lopez, L., Lovett-Racke, A., Lubberts, E., Ludewig, B., Lugli, E., Maecker, HT., Martrus, G., Matarese, G., Maueröder, C., McGrath, M., McInnes, I., Mei, HE., Melchers, F., Melzer, S., Mielenz, D., Mills, K., Mirrer, D., Mjösberg, J., Moore, J., Moran, B., Moretta, A., Moretta, L., Mosmann, TR., Müller, S., Müller, W., Münz, C., Multhoff, G., Munoz, LE., Murphy, KM., Nakayama, T., Nasi, M., Neudörfl, C., Nolan, J., Nourshargh, S., O'Connor, JE., Ouyang, W., Oxenius, A., Palankar, R., Panse, I., Peterson, P., Peth, C., Petriz, J., Philips, D., Pickl, W., Piconese, S., Pinti, M., Pockley, AG., Podolska, MJ., Pucillo, C., Quataert, SA., Radstake, TRDJ., Rajwa, B., Rebhahn, JA., Recktenwald, D., Remmerswaal, EBM., Rezvani, K., Rico, LG., Robinson, JP., Romagnani, C., Rubartelli, A., Ruckert, B., Ruland, J., Sakaguchi, S., Sala-de-Oyanguren, F., Samstag, Y., Sanderson, S., Sawitzki, B., Scheffold, A., Schiemann, M., Schildberg, F., Schimisky, E., Schmid, SA., Schmitt, S., Schober, K., Schüler, T., Schulz, AR., Schumacher, T., Scotta, C., Shankey, TV., Shemer, A., Simon, AK., Spidlen, J., Stall, AM., Stark, R., Stehle, C., Stein, M., Steinmetz, T., Stockinger, H., Takahama, Y., Tarnok, A., Tian, Z., Toldi, G., Tornack, J., Traggiai, E., Trotter, J., Ulrich, H., van der Braber, M., van Lier, RAW., Veldhoen, M., Vento-Asturias, S., Vieira, P., Voehringer, D., Volk, HD., von Volkmann, K., Waisman, A., Walker, R., Ward, MD., Warnatz, K., Warth, S., Watson, JV., Watzl, C., Wegener, L., Wiedemann, A., Wienands, J., Willimsky, G., Wing, J., Wurst, P., Yu, L., Yue, A., Zhang, Q., Zhao, Y., Ziegler, S. & Zimmermann, J., 2017, In : European Journal of Immunology. 47, 10, p. 1584-1797 214 p.

Research output: Contribution to journalArticle

Flow Cytometry
Guidelines

Guidelines for the use of flow cytometry and cell sorting in immunological studies

Cossarizza, A., Chang, H-D., Radbruch, A., Akdis, M., Andrä, I., Annunziato, F., Bacher, P., Barnaba, V., Battistini, L., Bauer, W. M., Baumgart, S., Becher, B., Beisker, W., Berek, C., Blanco, A., Borsellino, G., Boulais, P. E., Brinkman, R. R., Büscher, M., Busch, D. H. & 216 others, Bushnell, T. P., Cao, X., Cavani, A., Chattopadhyay, P. K., Cheng, Q., Chow, S., Clerici, M., Cooke, A., Cosma, A., Cosmi, L., Cumano, A., Dang, V. D., Davies, D., De Biasi, S., Del Zotto, G., Della Bella, S., Dellabona, P., Deniz, G., Dessing, M., Diefenbach, A., Di Santo, J., Dieli, F., Dolf, A., Donnenberg, V. S., Dörner, T., Ehrhardt, G. R. A., Endl, E., Engel, P., Engelhardt, B., Esser, C., Everts, B., Dreher, A., Falk, C. S., Fehniger, T. A., Filby, A., Fillatreau, S., Follo, M., Förster, I., Foster, J., Foulds, G. A., Frenette, P. S., Galbraith, D., Garbi, N., García-Godoy, M. D., Geginat, J., Ghoreschi, K., Gibellini, L., Goettlinger, C., Goodyear, C. S., Gori, A., Grogan, J., Gross, M., Grützkau, A., Grummitt, D., Hahn, J., Hammer, Q., Hauser, A. E., Haviland, D. L., Hedley, D., Herrera, G., Herrmann, M., Hiepe, F., Holland, T., Hombrink, P., Houston, J. P., Hoyer, B. F., Huang, B., Hunter, C. A., Iannone, A., Jäck, H-M., Jávega, B., Jonjic, S., Juelke, K., Jung, S., Kaiser, T., Kalina, T., Keller, B., Khan, S., Kienhöfer, D., Kroneis, T., Kunkel, D., Kurts, C., Kvistborg, P., Lannigan, J., Lantz, O., Larbi, A., LeibundGut-Landmann, S., Leipold, M. D., Levings, M. K., Litwin, V., Liu, Y., Lohoff, M., Lombardi, G., Lopez, L., Lovett-Racke, A., Lubberts, E., Ludewig, B., Lugli, E., Maecker, H. T., Martrus, G., Matarese, G., Maueröder, C., McGrath, M., McInnes, I., Mei, H. E., Melchers, F., Melzer, S., Mielenz, D., Mills, K., Mirrer, D., Mjösberg, J., Moore, J., Moran, B., Moretta, A., Moretta, L., Mosmann, T. R., Müller, S., Müller, W., Münz, C., Multhoff, G., Munoz, L. E., Murphy, K. M., Nakayama, T., Nasi, M., Neudörfl, C., Nolan, J., Nourshargh, S., O'Connor, J-E., Ouyang, W., Oxenius, A., Palankar, R., Panse, I., Peterson, P., Peth, C., Petriz, J., Philips, D., Pickl, W., Piconese, S., Pinti, M., Pockley, A. G., Podolska, M. J., Pucillo, C., Quataert, S. A., Radstake, T. R. D. J., Rajwa, B., Rebhahn, J. A., Recktenwald, D., Remmerswaal, E. B. M., Rezvani, K., Rico, L. G., Robinson, J. P., Romagnani, C., Rubartelli, A., Ruckert, B., Ruland, J., Sakaguchi, S., Sala-de-Oyanguren, F., Samstag, Y., Sanderson, S., Sawitzki, B., Scheffold, A., Schiemann, M., Schildberg, F., Schimisky, E., Schmid, S. A., Schmitt, S., Schober, K., Schüler, T., Schulz, A. R., Schumacher, T., Scotta, C., Shankey, T. V., Shemer, A., Simon, A-K., Spidlen, J., Stall, A. M., Stark, R., Stehle, C., Stein, M., Steinmetz, T., Stockinger, H., Takahama, Y., Tarnok, A., Tian, Z., Toldi, G., Tornack, J., Traggiai, E., Trotter, J., Ulrich, H., van der Braber, M., van Lier, R. A. W., Veldhoen, M., Vento-Asturias, S., Vieira, P., Voehringer, D., Volk, H-D., von Volkmann, K., Waisman, A., Walker, R., Ward, M. D., Warnatz, K., Warth, S., Watson, J. V., Watzl, C., Wegener, L., Wiedemann, A., Wienands, J., Willimsky, G., Wing, J., Wurst, P., Yu, L., Yue, A., Zhang, Q., Zhao, Y., Ziegler, S. & Zimmermann, J., Oct 1 2017, In : European Journal of Immunology. 47, 10, p. 1584-1797 214 p.

Research output: Contribution to journalArticle

High-dose ascorbate and arsenic trioxide selectively kill acute myeloid leukemia and acute promyelocytic leukemia blasts in vitro

Noguera, N. I., Pelosi, E., Angelini, D. F., Piredda, M. L., Guerrera, G., Piras, E., Battistini, L., Massai, L., Berardi, A., Catalano, G., Cicconi, L., Castelli, G., D'Angiò, A., Pasquini, L., Graziani, G., Fioritoni, G., Voso, M. T., Mastrangelo, D., Testa, U. & Lo-Coco, F., Jan 1 2017, In : Oncotarget. 8, 20, p. 32550-32565 16 p.

Research output: Contribution to journalArticle

Acute Promyelocytic Leukemia
Acute Myeloid Leukemia
Caspases
Fetal Blood
Transcriptional Activation

Increased PSA expression on prostate cancer exosomes in in vitro condition and in cancer patients

Logozzi, M., Angelini, D. F., Iessi, E., Mizzoni, D., Di Raimo, R., Federici, C., Lugini, L., Borsellino, G., Gentilucci, A., Pierella, F., Marzio, V., Sciarra, A., Battistini, L. & Fais, S., Sep 10 2017, In : Cancer Letters. 403, p. 318-329 12 p.

Research output: Contribution to journalArticle

Exosomes
Prostate-Specific Antigen
Prostatic Neoplasms
Neoplasms
Prostatic Hyperplasia

Modulation of P2X7 receptor during inflammation in multiple sclerosis

Amadio, S., Parisi, C., Piras, E., Fabbrizio, P., Apolloni, S., Montilli, C., Luchetti, S., Ruggieri, S., Gasperini, C., Laghi-Pasini, F., Battistini, L. & Volonté, C., Nov 15 2017, In : Frontiers in Immunology. 8, NOV, 1529.

Research output: Contribution to journalArticle

Purinergic P2X7 Receptors
Multiple Sclerosis
Inflammation
Monocytes
Chronic Progressive Multiple Sclerosis

Programmed death 1 is highly expressed on CD8+ CD57+ T cells in patients with stable multiple sclerosis and inhibits their cytotoxic response to Epstein–Barr virus

Cencioni, M. T., Magliozzi, R., Nicholas, R., Ali, R., Malik, O., Reynolds, R., Borsellino, G., Battistini, L. & Muraro, P. A., Dec 1 2017, In : Immunology. 152, 4, p. 660-676 17 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Viruses
T-Lymphocytes
Tissue Donors
Central Nervous System
2016

Altered intestinal permeability in patients with relapsing-remitting multiple sclerosis: A pilot study

Buscarinu, M. C., Cerasoli, B., Annibali, V., Policano, C., Lionetto, L., Capi, M., Mechelli, R., Romano, S., Fornasiero, A., Mattei, G., Piras, E., Angelini, D. F., Battistini, L., Simmaco, M., Umeton, R., Salvetti, M. & Ristori, G., Jul 11 2016, In : Multiple Sclerosis. 23, 3, p. 442-446 5 p.

Research output: Contribution to journalArticle

Relapsing-Remitting Multiple Sclerosis
Permeability
Mannitol
Multiple Sclerosis
Tissue Donors

Fas-fas ligand: Checkpoint of t cell functions in multiple sclerosis

Volpe, E., Sambucci, M., Battistini, L. & Borsellino, G., Sep 27 2016, In : Frontiers in Immunology. 7, SEP, 382.

Research output: Contribution to journalShort survey

Fas Ligand Protein
Multiple Sclerosis
Autoantigens
Regulatory T-Lymphocytes
T-Lymphocytes

Modulation of monocytes by bioactive lipid anandamide in multiple sclerosis involves distinct Toll-like receptors

Chiurchiu, V., Leuti, A., Cencioni, M. T., Albanese, M., De Bardi, M., Bisogno, T., Centonze, D., Battistini, L. & Maccarrone, M., Nov 1 2016, In : Pharmacological Research. 113, p. 313-319 7 p.

Research output: Contribution to journalArticle

Toll-Like Receptors
Endocannabinoids
Multiple Sclerosis
Monocytes
Lipids

Modulation of monocytes by bioactive lipid anandamide in multiple sclerosis involves distinct Toll-like receptors

Chiurchiù, V., Leuti, A., Cencioni, M. T., Albanese, M., De Bardi, M., Bisogno, T., Centonze, D., Battistini, L. & Maccarrone, M., Nov 1 2016, In : Pharmacological Research. 113, p. 313-319 7 p.

Research output: Contribution to journalArticle

Toll-Like Receptors
Endocannabinoids
Multiple Sclerosis
Monocytes
Lipids

Proresolving lipid mediators resolvin D1, resolvin D2, and maresin 1 are critical in modulating T cell responses

Chiurchiù, V., Leuti, A., Dalli, J., Jacobsson, A., Battistini, L., MaCcarrone, M. & Serhan, C. N., Aug 24 2016, In : Science Translational Medicine. 8, 353, 353ra111.

Research output: Contribution to journalArticle

T-Lymphocytes
Lipids
Docosahexaenoic Acids
Regulatory T-Lymphocytes
Th17 Cells

Siponimod (BAF312) prevents synaptic neurodegeneration in experimental multiple sclerosis

Gentile, A., Musella, A., Bullitta, S., Fresegna, D., De Vito, F., Fantozzi, R., Piras, E., Gargano, F., Borsellino, G., Battistini, L., Schubart, A., Mandolesi, G. & Centonze, D., Aug 26 2016, In : Journal of Neuroinflammation. 13, 1, 207.

Research output: Contribution to journalArticle

Autoimmune Experimental Encephalomyelitis
Multiple Sclerosis
Lymphocyte Count
Neuroprotective Agents
1-(4-(1-((E)-4-cyclohexyl-3-trifluoromethylbenzyloxyimino)-ethyl)-2-ethylbenzyl)-azetidine-3-carboxylic acid

Siponimod (BAF312) prevents synaptic neurodegeneration in experimental multiple sclerosis

Gentile, A., Musella, A., Bullitta, S., Fresegna, D., De Vito, F., Fantozzi, R., Piras, E., Gargano, F., Borsellino, G., Battistini, L., Schubart, A., Mandolesi, G. & Centonze, D., Aug 26 2016, In : Journal of Neuroinflammation. 13, 1, p. 207

Research output: Contribution to journalArticle

Autoimmune Experimental Encephalomyelitis
Multiple Sclerosis
Lymphocyte Count
Neuroprotective Agents
1-(4-(1-((E)-4-cyclohexyl-3-trifluoromethylbenzyloxyimino)-ethyl)-2-ethylbenzyl)-azetidine-3-carboxylic acid
2015
Th17 Cells
Multiple Sclerosis
Cell Biology
Autoimmune Diseases
Virulence

A Leukemia-Associated CD34/CD123/CD25/CD99+ Immunophenotype Identifies FLT3-Mutated Clones in Acute Myeloid Leukemia

Angelini, D. F., Ottone, T., Guerrera, G., Lavorgna, S., Cittadini, M., Buccisano, F., De Bardi, M., Gargano, F., Maurillo, L., Divona, M., Noguera, N. I., Consalvo, M. I. R., Borsellino, G., Bernardi, G., Amadori, S., Venditti, A., Battistini, L. & Lo-Coco, F., Sep 1 2015, In : Clinical Cancer Research. 21, 17, p. 3977-3985 9 p.

Research output: Contribution to journalArticle

fms-Like Tyrosine Kinase 3
Acute Myeloid Leukemia
Leukemia
Clone Cells
Mutation

Epstein-Barr virus genetic variants are associated with multiple sclerosis

Mechelli, R., Manzari, C., Policano, C., Annese, A., Picardi, E., Umeton, R., Fornasiero, A., D'Erchia, A. M., Buscarinu, M. C., Agliardi, C., Annibali, V., Serafini, B., Rosicarelli, B., Romano, S., Angelini, D. F., Ricigliano, V. A. G., Buttari, F., Battistini, L., Centonze, D., Guerini, F. R. & 4 others, D'Alfonso, S., Pesole, G., Salvetti, M. & Ristori, G., Mar 31 2015, In : Neurology. 84, 13, p. 1362-1368 7 p.

Research output: Contribution to journalArticle

Nuclear Antigens
Human Herpesvirus 4
Multiple Sclerosis
Alleles
Tissue Donors
Th17 Cells
Th1 Cells
Multiple Sclerosis
Cell Death
Tissue Donors
G-Protein-Coupled Receptors
Natural Killer Cells
Monocytes
Interleukin-12
Cannabidiol

T helper 9 cells induced by plasmacytoid dendritic cells regulate interleukin-17 in multiple sclerosis

Ruocco, G., Rossi, S., Motta, C., Macchiarulo, G., Barbieri, F., De Bardi, M., Borsellino, G., Finardi, A., Grasso, M. G., Ruggieri, S., Gasperini, C., Furlan, R., Centonze, D., Battistini, L. & Volpe, E., 2015, In : Clinical Science. 129, 4, p. 291-303 13 p.

Research output: Contribution to journalArticle

Interleukin-17
Interleukin-9
Helper-Inducer T-Lymphocytes
Dendritic Cells
Multiple Sclerosis

The p38 mitogen-activated protein kinase cascade modulates T helper type 17 differentiation and functionality in multiple sclerosis

Di Mitri, D., Sambucci, M., Loiarro, M., De Bardi, M., Volpe, E., Cencioni, M. T., Gasperini, C., Centonze, D., Sette, C., Akbar, A. N., Borsellino, G. & Battistini, L., Oct 1 2015, In : Immunology. 146, 2, p. 251-263 13 p.

Research output: Contribution to journalArticle

Relapsing-Remitting Multiple Sclerosis
p38 Mitogen-Activated Protein Kinases
Autoimmune Diseases
Multiple Sclerosis
Phosphorylation
2014

CD28 ligation in the absence of TCR stimulation up-regulates IL-17A and pro-inflammatory cytokines in relapsing-remitting multiple sclerosis T lymphocytes

Camperio, C., Muscolini, M., Volpe, E., Di Mitri, D., Mechelli, R., Buscarinu, M. C., Ruggieri, S., Piccolella, E., Salvetti, M., Gasperini, C., Battistini, L. & Tuosto, L., Mar 2014, In : Immunology Letters. 158, 1-2, p. 134-142 9 p.

Research output: Contribution to journalArticle

Relapsing-Remitting Multiple Sclerosis
Interleukin-17
Ligation
Up-Regulation
Tissue Donors

Interleukin-1β causes excitotoxic neurodegeneration and multiple sclerosis disease progression by activating the apoptotic protein p53

Rossi, S., Motta, C., Studer, V., Macchiarulo, G., Volpe, E., Barbieri, F., Ruocco, G., Buttari, F., Finardi, A., Mancino, R., Weiss, S., Battistini, L., Martino, G., Furlan, R., Drulovic, J. & Centonze, D., 2014, In : Molecular Neurodegeneration. 9, p. 56 1 p.

Research output: Contribution to journalArticle

Interleukin-1
Multiple Sclerosis
Disease Progression
Proteins
Inflammation
2013
Cannabinoid Receptors
Glucocorticoid Receptors
Cannabinoid Receptor CB2
Anti-Inflammatory Agents
Glucocorticoids

A genetic variant of the anti-apoptotic protein Akt predicts natalizumab-induced lymphocytosis and post-natalizumab multiple sclerosis reactivation

Rossi, S., Motta, C., Studer, V., Monteleone, F., De Chiara, V., Buttari, F., Barbieri, F., Bernardi, G., Battistini, L., Cutter, G., Stüve, O., Salvetti, M. & Centonze, D., 2013, In : Multiple Sclerosis Journal. 19, 1, p. 59-68 10 p.

Research output: Contribution to journalArticle

Lymphocytosis
Apoptosis Regulatory Proteins
Multiple Sclerosis
Natalizumab
Lymphocytes

Distinct modulation of human myeloid and plasmacytoid dendritic cells by anandamide in multiple sclerosis

Chiurchiù, V., Cencioni, M. T., Bisicchia, E., De Bardi, M., Gasperini, C., Borsellino, G., Centonze, D., Battistini, L. & Maccarrone, M., May 2013, In : Annals of Neurology. 73, 5, p. 626-636 11 p.

Research output: Contribution to journalArticle

Dendritic Cells
Multiple Sclerosis
Endocannabinoids
Cytokines
Disease Progression

Fibroadipogenic progenitors mediate the ability of HDAC inhibitors to promote regeneration in dystrophic muscles of young, but not old Mdx mice

Mozzetta, C., Consalvi, S., Saccone, V., Tierney, M., Diamantini, A., Mitchell, K. J., Marazzi, G., Borsellino, G., Battistini, L., Sassoon, D., Sacco, A. & Puri, P. L., Apr 2013, In : EMBO Molecular Medicine. 5, 4, p. 626-639 14 p.

Research output: Contribution to journalArticle

Inbred mdx Mouse
Histone Deacetylase Inhibitors
Regeneration
Muscles
Skeletal Muscle Fibers

Increased CD8+ T Cell Response to Epstein-Barr Virus Lytic Antigens in the Active Phase of Multiple Sclerosis

Angelini, D. F., Serafini, B., Piras, E., Severa, M., Coccia, E. M., Rosicarelli, B., Ruggieri, S., Gasperini, C., Buttari, F., Centonze, D., Mechelli, R., Salvetti, M., Borsellino, G., Aloisi, F. & Battistini, L., Apr 2013, In : PLoS Pathogens. 9, 4, e1003220.

Research output: Contribution to journalArticle

Human Herpesvirus 4
Multiple Sclerosis
T-Lymphocytes
Antigens
Relapsing-Remitting Multiple Sclerosis