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Research Output 1997 2020

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11 Real-time prognostic evaluation in MDS

Malcovati, L., May 2009, In : Leukemia Research. 33, SUPPL. 1

Research output: Contribution to journalArticle

Aberrant splicing and defective mRNA production induced by somatic spliceosome mutations in myelodysplasia

Shiozawa, Y., Malcovati, L., Gallì, A., Sato-Otsubo, A., Kataoka, K., Sato, Y., Watatani, Y., Suzuki, H., Yoshizato, T., Yoshida, K., Sanada, M., Makishima, H., Shiraishi, Y., Chiba, K., Hellström-Lindberg, E., Miyano, S., Ogawa, S. & Cazzola, M., Dec 1 2018, In : Nature Communications. 9, 1, 3649.

Research output: Contribution to journalArticle

Spliceosomes
splicing
mutations
Genes
Messenger RNA

A complex translocation (5;7) in a patient with acute nonlymphocytic leukemia evolved from a myelodysplastic syndrome

Bernasconi, P., Cavigliano, P. M., Genini, E., Castagnola, C., Malcovati, L., Calatroni, S., Caresana, M., Boni, M., Alessandrino, E. P., Astori, C., Corso, A. & Bernasconi, C., Sep 1998, In : Cancer Genetics and Cytogenetics. 105, 2, p. 182-186 5 p.

Research output: Contribution to journalArticle

Chromosome Deletion
Myelodysplastic Syndromes
Acute Myeloid Leukemia
Chromosomes, Human, Pair 7
Chromosomes, Human, Pair 5

Adverse events occurring during bone marrow or peripheral blood progenitor cell infusion: Analysis of 126 cases

Alessandrino, E. P., Bernasconi, P., Caldera, D., Colombo, A., Bonfichi, M., Malcovati, L., Klersy, C., Martinelli, G., Maiocchi, M., Pagnucco, G., Varettoni, M., Perotti, C. & Bernasconi, C., 1999, In : Bone Marrow Transplantation. 23, 6, p. 533-537 5 p.

Research output: Contribution to journalArticle

Blood Cells
Stem Cells
Bone Marrow
Bradycardia
Hemoglobinuria

Allogeneic hematopoietic stem cell transplantation for MDS and CMML: recommendations from an international expert panel

Witte, T. D., Bowen, D., Robin, M., Malcovati, L., Niederwieser, D., Yakoub-Agha, I., Mufti, G. J., Fenaux, P., Sanz, G., Martino, R., Alessandrino, E. P., Onida, F., Symeonidis, A., Passweg, J., Kobbe, G., Ganser, A., Platzbecker, U., Finke, J., Gelder, M. V., Loosdrecht, A. A. V. D. & 10 others, Ljungman, P., Stauder, R., Volin, L., Deeg, H. J., Cutler, C., Saber, W., Champlin, R., Giralt, S., Anasetti, C. & Kroger, N., Mar 30 2017, In : Blood. 129, 13, p. 1753-1762 10 p.

Research output: Contribution to journalArticle

Leukemia, Myelomonocytic, Chronic
Hematopoietic Stem Cell Transplantation
Myelodysplastic Syndromes
Stem cells
Comorbidity

An international consortium proposal of uniform response criteria for myelodysplastic/myeloproliferative neoplasms (MDS/MPN) in adults

Savona, M. R., Malcovati, L., Komrokji, R., Tiu, R. V., Mughal, T. I., Orazi, A., Kiladjian, J. J., Padron, E., Solary, E., Tibes, R., Itzykson, R., Cazzola, M., Mesa, R., Maciejewski, J., Fenaux, P., Garcia-Manero, G., Gerds, A., Sanz, G., Niemeyer, C. M., Cervantes, F. & 3 others, Germing, U., Cross, N. C. P. & List, A. F., Mar 19 2015, In : Blood. 125, 12, p. 1857-1865 9 p.

Research output: Contribution to journalArticle

Stem cells
Myelodysplastic Syndromes
Neoplasms
Stem Cells
Clinical Trials

An international MDS/MPN working group’s perspective and recommendations on molecular pathogenesis, diagnosis and clinical characterization of myelodysplastic/myeloproliferative neoplasms

Mughal, T. I., Cross, N. C. P., Padron, E., Tiu, R. V., Savona, M., Malcovati, L., Tibes, R., Komrokji, R. S., Kiladjian, J. J., Garcia-Manero, G., Orazi, A., Mesa, R., Maciejewski, J. P., Fenaux, P., Itzykson, R., Mufti, G., Solary, E. & List, A. F., Sep 7 2015, In : Haematologica. 100, 9, p. 1117-1130 14 p.

Research output: Contribution to journalArticle

Refractory Anemia
Thrombocytosis
Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative
Juvenile Myelomonocytic Leukemia
Leukemia, Myelomonocytic, Chronic

A novel t(Y;11) translocation with MLL gene rearrangement in a case of acute myelomonocytic leukemia (AML-M4) [4]

Bernasconi, P., Cavigliano, P. M., Boni, M., Malcovati, L., Calatroni, S., Astori, C., Caresana, M. & Bernasconi, C., 1999, In : Leukemia. 13, 3, p. 487-489 3 p.

Research output: Contribution to journalArticle

Aplastic Anemia & MDS International Foundation (AA&MDSIF): Bone Marrow Failure Disease Scientific Symposium 2010

Malcovati, L., de Latour, R. P. & Risitano, A., Mar 2011, In : Leukemia Research. 35, 3, p. 291-294 4 p.

Research output: Contribution to journalArticle

Bone Marrow Diseases
Aplastic Anemia
Myelodysplastic Syndromes
Nonprofit Organizations
Research Personnel

appreci8: a pipeline for precise variant calling integrating 8 tools

Sandmann, S., Karimi, M., de Graaf, A. O., Rohde, C., Göllner, S., Varghese, J., Ernsting, J., Walldin, G., van der Reijden, B. A., Müller-Tidow, C., Malcovati, L., Hellström-Lindberg, E., Jansen, J. H. & Dugas, M., Dec 15 2018, In : Bioinformatics (Oxford, England). 34, 24, p. 4205-4212 8 p.

Research output: Contribution to journalArticle

Sequencing
Pipelines
Information Storage and Retrieval
Myelodysplastic Syndromes
Computational Biology

Assessment of chimerism in sex-mismatched allogeneic bone marrow transplants (allo-BMT) by in situ hybridization and cytogenetics. Is host cell percentage predictive of relapse? [3]

Bernasconi, P., Cavigliano, P. M., Genini, E., Alessandrino, E. P., Colombo, A., Klersy, C., Malcovati, L., Biaggi, G., Martinelli, G., Calatroni, S., Caresana, M., Boni, M., Astori, C. & Bernasconi, C., 1997, In : Leukemia. 11, 11, p. 1989-1990 2 p.

Research output: Contribution to journalArticle

Biological and clinical relevance of matrix metalloproteinases 2 and 9 in acute myeloid leukaemias and myelodysplastic syndromes

Travaglino, E., Benatti, C., Malcovati, L., Porta, M. G. D., Gallì, A., Bonetti, E., Rosti, V., Cazzola, M. & Invernizzi, R., Mar 2008, In : European Journal of Haematology. 80, 3, p. 216-226 11 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 2
Myelodysplastic Syndromes
Matrix Metalloproteinase 9
Matrix Metalloproteinases
Acute Myeloid Leukemia

Biologic and clinical significance of somatic mutations of SF3B1 in myeloid and lymphoid neoplasms

Cazzola, M., Rossi, M. & Malcovati, L., Jan 10 2013, In : Blood. 121, 2, p. 260-269 10 p.

Research output: Contribution to journalArticle

Spliceosomes
Genes
RNA Precursors
Mutation
Myelodysplastic Syndromes

Cannibalism by erythroleukaemic blasts

Travaglino, E. & Malcovati, L., 2018, In : British Journal of Haematology. 183, 1, p. 14

Research output: Contribution to journalArticle

Cerebral vasoreactivity in Andeans and headache at sea level

Appenzeller, O., Passino, C., Roach, R., Gamboa, J., Gamboa, A., Bernardi, L., Bonfichi, M. & Malcovati, L., Apr 15 2004, In : Journal of the Neurological Sciences. 219, 1-2, p. 101-106 6 p.

Research output: Contribution to journalArticle

Oceans and Seas
Altitude Sickness
Headache
Middle Cerebral Artery
Migraine Disorders

Chemotherapy and donor peripheral blood progenitor cells for acute leukemia in early relapse after allogeneic bone marrow transplantation

Alessandrino, E. P., Bernasconi, P., Caldera, D., Colombo, A., Malcovati, L., Martinelli, G., Bonfichi, M., Pagnucco, G., Salvaneschi, L. & Bernasconi, C., 1999, In : Bone Marrow Transplantation. 23, 6, p. 607-612 6 p.

Research output: Contribution to journalArticle

Homologous Transplantation
Bone Marrow Transplantation
Blood Cells
Leukemia
Stem Cells

Classification and prognostic evaluation of Myelodysplastic syndromes

Cazzola, M., Della Porta, M. G., Travaglino, E. & Malcovati, L., Oct 2011, In : Seminars in Oncology. 38, 5, p. 627-634 8 p.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
Bone Marrow
Survival
Acute Myeloid Leukemia
Cytogenetics

ClinGen Myeloid Malignancy Variant Curation Expert Panel recommendations for germline RUNX1 variants

Luo, X., Feurstein, S., Mohan, S., Porter, C. C., Jackson, S. A., Keel, S., Chicka, M., Brown, A. L., Kesserwan, C., Agarwal, A., Luo, M., Li, Z., Ross, J. E., Baliakas, P., Pineda-Alvarez, D., DiNardo, C. D., Bertuch, A. A., Mehta, N., Vulliamy, T., Wang, Y. & 14 others, Nichols, K. E., Malcovati, L., Walsh, M. F., Rawlings, L. H., McWeeney, S. K., Soulier, J., Raimbault, A., Routbort, M. J., Zhang, L., Ryan, G., Speck, N. A., Plon, S. E., Wu, D. & Godley, L. A., Oct 22 2019, In : Blood advances. 3, 20, p. 2962-2979 18 p.

Research output: Contribution to journalArticle

Open Access
Molecular Pathology
Genomics
Medical Genetics
Genome
Blood Platelets

Clinical, histopathological and molecular characterization of hypoplastic myelodysplastic syndrome

Bono, E., McLornan, D., Travaglino, E., Gandhi, S., Gallì, A., Khan, A. A., Kulasekararaj, A. G., Boveri, E., Raj, K., Elena, C., Ireland, R. M., Bianchessi, A., Jiang, J., Todisco, G., Ferretti, V. V., Cazzola, M., Marsh, J. C. W., Malcovati, L. & Mufti, G. J., Jan 1 2019, In : Leukemia.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
Bone Marrow
Aplastic Anemia
Chromosome Aberrations
Differential Diagnosis

Clinical and biological implications of driver mutations in myelodysplastic syndromes

Papaemmanuil, E., Gerstung, M., Malcovati, L., Tauro, S., Gundem, G., Van Loo, P., Yoon, C. J., Ellis, P., Wedge, D. C., Pellagatti, A., Shlien, A., Groves, M. J., Forbes, S. A., Raine, K., Hinton, J., Mudie, L. J., McLaren, S., Hardy, C., Latimer, C., Della Porta, M. G. & 18 others, O'Meara, S., Ambaglio, I., Galli, A., Butler, A. P., Walldin, G., Teague, J. W., Quek, L., Sternberg, A., Gambacorti-Passerini, C., Cross, N. C. P., Green, A. R., Boultwood, J., Vyas, P., Hellstrom-Lindberg, E., Bowen, D., Cazzola, M., Stratton, M. R. & Campbell, P. J., Nov 21 2013, In : Blood. 122, 22, p. 3616-3627 12 p.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
Genes
Mutation
RNA Splicing
RNA

Clinical evaluation of extra-hematologic comorbidity in myelodysplastic syndromes: Ready-to-wear versus made-to-measure tool

Della Porta, M. G., Ambaglio, I., Ubezio, M., Travaglino, E., Pascutto, C. & Malcovati, L., Apr 1 2012, In : Haematologica. 97, 4, p. 631-632 2 p.

Research output: Contribution to journalArticle

Clinical features and course of refractory anemia with ring sideroblasts associated with marked thrombocytosis

Broseus, J., Florensa, L., Zipperer, E., Schnittger, S., Malcovati, L., Richebourg, S., Lippert, E., Cermak, J., Evans, J., Mounier, M., Raya, J. M., Bailly, F., Gattermann, N., Haferlach, T., Garand, R., Allou, K., Besses, C., Germing, U., Haferlach, C., Travaglino, E. & 14 others, Luno, E., Pinan, M. A., Arenillas, L., Rozman, M., Sirvent, M. L. P., Favre, B., Guy, J., Alonso, E., Ahwij, N., Jerez, A., Hermouet, S., Maynadié, M., Cazzola, M. & Girodon, F., Jul 1 2012, In : Haematologica. 97, 7, p. 1036-1041 6 p.

Research output: Contribution to journalArticle

Refractory Anemia
Thrombocytosis
Essential Thrombocythemia
Survival
Janus Kinase 2

Clinical relevance of bone marrow fibrosis and CD34-positive cell clusters in primary mvelodvsplastic syndromes

Porta, M. G. D., Malcovati, L., Boveri, E., Travaglino, E., Pietra, D., Pascutto, C., Passamonti, F., Invernizzi, R., Castello, A., Magrini, U., Lazzarino, M. & Cazzola, M., Feb 10 2009, In : Journal of Clinical Oncology. 27, 5, p. 754-762 9 p.

Research output: Contribution to journalArticle

Primary Myelofibrosis
Leukemia
Survival
Myelodysplastic Syndromes
Cytogenetics

Clinical significance of genetic aberrations in secondary acute myeloid leukemia

Milosevic, J. D., Puda, A., Malcovati, L., Berg, T., Hofbauer, M., Stukalov, A., Klampfl, T., Harutyunyan, A. S., Gisslinger, H., Gisslinger, B., Burjanivova, T., Rumi, E., Pietra, D., Elena, C., Vannucchi, A. M., Doubek, M., Dvorakova, D., Robesova, B., Wieser, R., Koller, E. & 9 others, Suvajdzic, N., Tomin, D., Tosic, N., Colinge, J., Racil, Z., Steurer, M., Pavlovic, S., Cazzola, M. & Kralovics, R., Nov 2012, In : American Journal of Hematology. 87, 11, p. 1010-1016 7 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Karyotype
Mutation
Survival
Loss of Heterozygosity

Clinical significance of neutrophil CD177 mRNA expression in Ph-negative chronic myeloproliferative disorders

Passamonti, F., Pietra, D., Malabarba, L., Rumi, E., Della Porta, M. G., Malcovati, L., Bonfichi, M., Pascutto, C., Lazzarino, M. & Cazzola, M., Sep 2004, In : British Journal of Haematology. 126, 5, p. 650-656 7 p.

Research output: Contribution to journalArticle

Myeloproliferative Disorders
Neutrophils
Polycythemia Vera
Messenger RNA
Essential Thrombocythemia

Clinical significance of SF3B1 mutations in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms

Malcovati, L., Papaemmanuil, E., Bowen, D. T., Boultwood, J., Della Porta, M. G., Pascutto, C., Travaglino, E., Groves, M. J., Godfrey, A. L., Ambaglio, I., Gallì, A., Da Vià, M. C., Conte, S., Tauro, S., Keenan, N., Hyslop, A., Hinton, J., Mudie, L. J., Wainscoat, J. S., Futreal, P. A. & 4 others, Stratton, M. R., Campbell, P. J., Hellström-Lindberg, E. & Cazzola, M., Dec 8 2011, In : Blood. 118, 24, p. 6239-6246 8 p.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
Hazards
Mutation
Gene encoding
Risk assessment

Clinical significance of somatic mutation in unexplained blood cytopenia

Malcovati, L., Gallì, A., Travaglino, E., Ambaglio, I., Rizzo, E., Molteni, E., Elena, C., Ferretti, VV., Catricalà, S., Bono, E., Todisco, G., Bianchessi, A., Rumi, E., Zibellini, S., Pietra, D., Boveri, E., Camaschella, C., Toniolo, D., Papaemmanuil, E., Ogawa, S. & 1 others, Cazzola, M., 2017, In : Blood. 129, 25, p. 3371-3378 8 p.

Research output: Contribution to journalArticle

Blood
Genes
Mutation
Neoplasms
Hazards

Clinical significance of somatic mutation in unexplained blood cytopenia

Malcovati, L., Gallì, A., Travaglino, E., Ambaglio, I., Rizzo, E., Molteni, E., Elena, C., Ferretti, V. V., Catricalà, S., Bono, E., Todisco, G., Bianchessi, A., Rumi, E., Zibellini, S., Pietra, D., Boveri, E., Camaschella, C., Toniolo, D., Papaemmanuil, E., Ogawa, S. & 1 others, Cazzola, M., Jun 22 2017, In : Blood. 129, 25, p. 3371-3378 8 p.

Research output: Contribution to journalArticle

Blood
Genes
Mutation
Neoplasms
Hazards

Clinical utility of the absolute number of circulating CD34-positive cells in patients with chronic myeloproliferative disorders

Passamonti, F., Vanelli, L., Malabarba, L., Rumi, E., Pungolino, E., Malcovati, L., Pascutto, C., Morra, E., Lazzarino, M. & Cazzola, M., Oct 2003, In : Haematologica. 88, 10, p. 1123-1129 7 p.

Research output: Contribution to journalArticle

Myeloproliferative Disorders
Primary Myelofibrosis
Essential Thrombocythemia
Polycythemia Vera
Flow Cytometry

Combining gene mutation with gene expression data improves outcome prediction in myelodysplastic syndromes

Gerstung, M., Pellagatti, A., Malcovati, L., Giagounidis, A., Della Porta, M. G., Jädersten, M., Dolatshad, H., Verma, A., Cross, N. C. P., Vyas, P., Killick, S., Hellström-Lindberg, E., Cazzola, M., Papaemmanuil, E., Campbell, P. J. & Boultwood, J., Jan 9 2015, In : Nature Communications. 6, 5901.

Research output: Contribution to journalArticle

gene expression
Myelodysplastic Syndromes
mutations
Gene expression
genes

Complex Patterns of Chromosome 11 Aberrations in Myeloid Malignancies Target CBL, MLL, DDB1 and LMO2

Klampfl, T., Milosevic, J. D., Puda, A., Schönegger, A., Bagienski, K., Berg, T., Harutyunyan, A. S., Gisslinger, B., Rumi, E., Malcovati, L., Pietra, D., Elena, C., Della Porta, M. G., Pieri, L., Guglielmelli, P., Bock, C., Doubek, M., Dvorakova, D., Suvajdzic, N., Tomin, D. & 8 others, Tosic, N., Racil, Z., Steurer, M., Pavlovic, S., Vannucchi, A. M., Cazzola, M., Gisslinger, H. & Kralovics, R., Oct 16 2013, In : PLoS One. 8, 10, e77819.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 11
Chromosomes
Aberrations
Chromosome Aberrations
Exome

Cytogenetic and FISH analyses in five patients with hypoplastic bone marrow [5]

Bernasconi, P., Astori, C., Cavigliano, P. M., Boni, M., Malcovati, L., Calatroni, S., Caresana, M. & Bernasconi, C., 2000, In : Leukemia. 14, 7, p. 1322 1 p.

Research output: Contribution to journalArticle

Cytomorphology review of 100 newly diagnosed lower-risk MDS patients in the European LeukemiaNet MDS (EUMDS) registry reveals a high inter-observer concordance

de Swart, L., Smith, A., MacKenzie, M., Symeonidis, A., Neukirchen, J., Mikulenková, D., Vallespí, T., Zini, G., Paszkowska-Kowalewska, M., Kruger, A., Saft, L., Fenaux, P., Bowen, D., Hellström-Lindberg, E., Čermák, J., Stauder, R., Tatic, A., Holm, M. S., Malcovati, L., Mądry, K. & 4 others, Droste, J., Blijlevens, N., de Witte, T. & Germing, U., Jul 1 2017, In : Annals of Hematology. 96, 7, p. 1105-1112 8 p.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
Registries
Bone Marrow
Myelopoiesis
Observer Variation

Decision analysis of allogeneic hematopoietic stem cell transplantation for patients with myelodysplastic syndrome stratified according to the revised International Prognostic Scoring System

Porta, M. G. D., Jackson, C. H., Alessandrino, E. P., Rossi, M., Bacigalupo, A., Lint, M. T. V., Bernardi, M., Allione, B., Bosi, A., Guidi, S., Santini, V., Malcovati, L., Ubezio, M., Milanesi, C., Todisco, E., Voso, M. T., Musto, P., Onida, F., Iori, A. P., Cerretti, R. & 13 others, Grillo, G., Molteni, A., Pioltelli, P., Borin, L., Angelucci, E., Oldani, E., Sica, S., Pascutto, C., Ferretti, V., Santoro, A., Bonifazi, F., Cazzola, M. & Rambaldi, A., Nov 1 2017, In : Leukemia. 31, 11, p. 2449-2457 9 p.

Research output: Contribution to journalArticle

Decision Support Techniques
Hematopoietic Stem Cell Transplantation
Myelodysplastic Syndromes
Life Expectancy
Transplantation

Decision analysis of allogeneic hematopoietic stem cell transplantation for patients with myelodysplastic syndrome stratified according to the revised International Prognostic Scoring System

della Porta, M. G., Jackson, C. H., Alessandrino, E. P., Rossi, M., Bacigalupo, A., van Lint, M. T., Bernardi, M., Allione, B., Bosi, A., Guidi, S., Santini, V., Malcovati, L., Ubezio, M., Milanesi, C., Todisco, E., Voso, M. T., Musto, P., Onida, F., Iori, A. P., Cerretti, R. & 13 others, Grillo, G., Molteni, A., Pioltelli, P., Borin, L., Angelucci, E., Oldani, E., Sica, S., Pascutto, C., Ferretti, V., Santoro, A., Bonifazi, F., Cazzola, M. & Rambaldi, A., 2017, In : Leukemia. 31, 11, p. 2449-2457

Research output: Contribution to journalArticle

Decision Support Techniques
Hematopoietic Stem Cell Transplantation
Myelodysplastic Syndromes
Life Expectancy
Transplantation

Decision analysis of allogeneic hematopoietic stem cell transplantation for patients with myelodysplastic syndrome stratified according to the revised International Prognostic Scoring System

della Porta, M. G., Jackson, C. H., Alessandrino, E. P., Rossi, M., Bacigalupo, A., van Lint, M. T., Bernardi, M., Allione, B., Bosi, A., Guidi, S., Santini, V., Malcovati, L., Ubezio, M., Milanesi, C., Todisco, E., Voso, M. T., Musto, P., Onida, F., Iori, A. P., Cerretti, R. & 13 others, Grillo, G., Molteni, A., Pioltelli, P., Borin, L., Angelucci, E., Oldani, E., Sica, S., Pascutto, C., Ferretti, V., Santoro, A., Bonifazi, F., Cazzola, M. & Rambaldi, A., 2017, In : Leukemia. 31, 11, p. 2449-2457 9 p.

Research output: Contribution to journalArticle

Decision Support Techniques
Hematopoietic Stem Cell Transplantation
Myelodysplastic Syndromes
Life Expectancy
Transplantation

Decision analysis of allogeneic hematopoietic stem cell transplantation for patients with myelodysplastic syndrome stratified according to the revised international prognostic scoring system (IPSS-R)

Della Porta, M. G., Jackson, C. H., Alessandrino, E. P., Rossi, M., Bacigalupo, A., van Lint, M. T., Bernardi, M., Allione, B., Bosi, A., Guidi, S., Santini, V., Malcovati, L., Ubezio, M. C., Milanesi, C., Todisco, E., Voso, M. T., Musto, P., Onida, F., Iori, A. P., Cerretti, R. & 13 others, Grillo, G., Molteni, A., Pioltelli, P., Borin, L., Angelucci, E., Oldani, E., Sica, G. S., Pascutto, C., Ferretti, V., Santoro, A., Bonifazi, F., Cazzola, M. & Rambaldi, A., Mar 21 2017, In : Leukemia.

Research output: Contribution to journalArticle

Decision Support Techniques
Hematopoietic Stem Cell Transplantation
Myelodysplastic Syndromes
Life Expectancy
Transplantation

Decision analysis of allogeneic hematopoietic stem cell transplantation for patients with myelodysplastic syndrome stratified according to the revised international prognostic scoring system (IPSS-R)

Della Porta, M. G., Jackson, C. H., Alessandrino, E. P., Rossi, M., Bacigalupo, A., van Lint, M. T., Bernardi, M., Allione, B., Bosi, A., Guidi, S., Santini, V., Malcovati, L., Ubezio, M. C., Milanesi, C., Todisco, E., Voso, M. T., Musto, P., Onida, F., Iori, A. P., Cerretti, R. & 13 others, Grillo, G., Molteni, A., Pioltelli, P., Borin, L., Angelucci, E., Oldani, E., Sica, G. S., Pascutto, C., Ferretti, V., Santoro, A., Bonifazi, F., Cazzola, M. & Rambaldi, A., Mar 21 2017, In : Leukemia.

Research output: Contribution to journalArticle

Decision Support Techniques
Hematopoietic Stem Cell Transplantation
Myelodysplastic Syndromes
Life Expectancy
Transplantation

Dendritic cell recovery after allogeneic stem-cell transplantation in acute leukemia: Correlations with clinical and transplant characteristics

Della Porta, M., Rigolin, G. M., Alessandrino, E. P., Maiocchi, M., Malcovati, L., Vanelli, L., Baratè, C., Rumi, E., Ciccone, M., Cuneo, A., Lazzarino, M. & Castoldi, G., Jan 2004, In : European Journal of Haematology. 72, 1, p. 18-25 8 p.

Research output: Contribution to journalArticle

Stem Cell Transplantation
Dendritic Cells
Leukemia
Transplants
Hematopoietic Stem Cell Transplantation

Deregulated gene expression pathways in myelodysplastic syndrome hematopoietic stem cells

Pellagatti, A., Cazzola, M., Giagounidis, A., Perry, J., Malcovati, L., Della Porta, M. G., Jädersten, M., Killick, S., Verma, A., Norbury, C. J., Hellström-Lindberg, E., Wainscoat, J. S. & Boultwood, J., Apr 2010, In : Leukemia. 24, 4, p. 756-764 9 p.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
Hematopoietic Stem Cells
Gene Expression
Thrombopoietin
Gene Ontology

Detection of minimal residual disease in acute lymphoblastic leukemia

Della Porta, M. G. & Malcovati, L., Nov 2005, In : Haematologica. 90, 11, p. 1445-1446 2 p.

Research output: Contribution to journalArticle

Development and validation of a prognostic scoring system for patients with chronic myelomonocytic leukemia

Such, E., Germing, U., Malcovati, L., Cervera, J., Kuendgen, A., Della Porta, M. G., Nomdedeu, B., Arenillas, L., Luño, E., Xicoy, B., Amigo, M. L., Valcarcel, D., Nachtkamp, K., Ambaglio, I., Hildebrandt, B., Lorenzo, I., Cazzola, M. & Sanz, G., Apr 11 2013, In : Blood. 121, 15, p. 3005-3015 11 p.

Research output: Contribution to journalArticle

Leukemia, Myelomonocytic, Chronic
Blood
Erythrocyte Transfusion
Acute Myeloid Leukemia
Cytogenetics

Development and validation of a prognostic scoring system for patients with chronic myelomonocytic leukemia

Such, E., Germing, U., Malcovati, L. & Hrodek, O., 2013, In : Transfuze a Hematologie Dnes. 19, 3, p. 191 1 p.

Research output: Contribution to journalArticle

Diagnosis and treatment of primary myelodysplastic syndromes in adults: Recommendations from the European LeukemiaNet

Malcovati, L., Hellström-Lindberg, E., Bowen, D., Adès, L., Cermak, J., Del Cañizo, C., Della Porta, M. G., Fenaux, P., Gattermann, N., Germing, U., Jansen, J. H., Mittelman, M., Mufti, G., Platzbecker, U., Sanz, G. F., Selleslag, D., Skov-Holm, M., Stauder, R., Symeonidis, A., Van De Loosdrecht, A. A. & 2 others, De Witte, T. & Cazzola, M., Oct 24 2013, In : Blood. 122, 17, p. 2943-2964 22 p.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
Health
Stem cells
Risk assessment
Comorbidity

Diagnostic utility of flow cytometry in low-grade myelodysplastic syndromes: A prospective validation study

Ogata, K., Della Porta, M. G., Malcovati, L., Picone, C., Yokose, N., Matsuda, A., Yamashita, T., Tamura, H., Tsukada, J. & Dan, K., Aug 2009, In : Haematologica. 94, 8, p. 1066-1074 9 p.

Research output: Contribution to journalArticle

Validation Studies
Myelodysplastic Syndromes
Flow Cytometry
Prospective Studies
Multiple Abnormalities

Differing clinical features between Japanese and Caucasian patients with myelodysplastic syndromes: Analysis from the International Working Group for Prognosis of MDS

Miyazaki, Y., Tuechler, H., Sanz, G., Schanz, J., Garcia-Manero, G., Solé, F., Bennett, J. M., Bowen, D., Fenaux, P., Dreyfus, F., Kantarjian, H., Kuendgen, A., Malcovati, L., Cazzola, M., Cermak, J., Fonatsch, C., Le Beau, M. M., Slovak, M. L., Santini, V., Lübbert, M. & 14 others, Maciejewski, J., Machherndl-Spandl, S., Magalhaes, S. M. M., Pfeilstöcker, M., Sekeres, M. A., Sperr, W. R., Stauder, R., Tauro, S., Valent, P., Vallespi, T., van de Loosdrecht, A. A., Germing, U., Haase, D. & Greenberg, P. L., Oct 1 2018, In : Leukemia Research. 73, p. 51-57 7 p.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
Cytogenetics
Survival
Intrinsic Factor
Acute Myeloid Leukemia

Disclosing the Impact of Carcinogenic SF3b Mutations on Pre-mRNA Recognition Via All-Atom Simulations

Borišek, J., Saltalamacchia, A., Gallì, A., Palermo, G., Molteni, E., Malcovati, L. & Magistrato, A., Oct 21 2019, In : Biomolecules. 9, 10

Research output: Contribution to journalArticle

Open Access
Spliceosomes
RNA Splice Sites
RNA Precursors
RNA Splicing
Atoms

Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells

Dolatshad, H., Pellagatti, A., Fernandez-Mercado, M., Yip, B. H., Malcovati, L., Attwood, M., Przychodzen, B., Sahgal, N., Kanapin, A. A., Lockstone, H., Scifo, L., Vandenberghe, P., Papaemmanuil, E., Smith, C. W. J., Campbell, P. J., Ogawa, S., Maciejewski, J. P., Cazzola, M., Savage, K. I. & Boultwood, J., May 11 2015, In : Leukemia. 29, 5, p. 1092-1103 12 p.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
Hematopoietic Stem Cells
Refractory Anemia
Genes
RNA