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Research Output 1997 2020

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2010

Prognostic classification and risk assessment in myelodysplastic syndromes

Cazzola, M. & Malcovati, L., Apr 2010, In : Hematology/Oncology Clinics of North America. 24, 2, p. 459-468 10 p.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
Primary Myelofibrosis
Survival
Life Expectancy
Acute Myeloid Leukemia

Prognostic impact of pre-transplantation transfusion history and secondary iron overload in patients with myelodysplastic syndrome undergoing allogeneic stem cell transplantation: A GITMO study

Alessandrino, E. P., Della Porta, M. G., Bacigalupo, A., Malcovati, L., Angelucci, E., Van Lint, M. T., Falda, M., Onida, F., Bernardi, M., Guidi, S., Lucarelli, B., Rambaldi, A., Cerretti, R., Marenco, P., Pioltelli, P., Pascutto, C., Oneto, R., Pirolini, L., Fanin, R. & Bosi, A., Mar 2010, In : Haematologica. 95, 3, p. 476-484 9 p.

Research output: Contribution to journalArticle

Iron Overload
Myelodysplastic Syndromes
Stem Cell Transplantation
Transplantation
History

Sequence variations in mitochondrial ferritin: Distribution in healthy controls and different types of patients

Castiglioni, E., Finazzi, D., Goldwurm, S., Levi, S., Pezzoli, G., Garavaglia, B., Nardocci, N., Malcovati, L., Porta, M. G. D., Gallì, A., Forni, G. L., Girelli, D., MacCarinelli, F., Poli, M., Ferrari, M., Cremonesi, L. & Arosio, P., Dec 1 2010, In : Genetic Testing and Molecular Biomarkers. 14, 6, p. 793-796 4 p.

Research output: Contribution to journalArticle

Ferritins
Iron
Myelodysplastic Syndromes
Movement Disorders
Parkinson Disease
2009

11 Real-time prognostic evaluation in MDS

Malcovati, L., May 2009, In : Leukemia Research. 33, SUPPL. 1

Research output: Contribution to journalArticle

Clinical relevance of bone marrow fibrosis and CD34-positive cell clusters in primary mvelodvsplastic syndromes

Porta, M. G. D., Malcovati, L., Boveri, E., Travaglino, E., Pietra, D., Pascutto, C., Passamonti, F., Invernizzi, R., Castello, A., Magrini, U., Lazzarino, M. & Cazzola, M., Feb 10 2009, In : Journal of Clinical Oncology. 27, 5, p. 754-762 9 p.

Research output: Contribution to journalArticle

Primary Myelofibrosis
Leukemia
Survival
Myelodysplastic Syndromes
Cytogenetics

Diagnostic utility of flow cytometry in low-grade myelodysplastic syndromes: A prospective validation study

Ogata, K., Della Porta, M. G., Malcovati, L., Picone, C., Yokose, N., Matsuda, A., Yamashita, T., Tamura, H., Tsukada, J. & Dan, K., Aug 2009, In : Haematologica. 94, 8, p. 1066-1074 9 p.

Research output: Contribution to journalArticle

Validation Studies
Myelodysplastic Syndromes
Flow Cytometry
Prospective Studies
Multiple Abnormalities

Haploinsufficiency of RPS14 in 5q- syndrome is associated with deregulation of ribosomal- and translation-related genes (British Journal of Haematology (2008) 142, (57-64))

Pellagatti, A., Hellström-Lindberg, E., Giagounidis, A., Perry, J., Malcovati, L., Della Porta, M. G., Jädersten, M., Killick, S., Fidler, C., Cazzola, M., Wainscoat, J. S. & Boultwood, J., Feb 2009, In : British Journal of Haematology. 144, 3, p. 455 1 p.

Research output: Contribution to journalArticle

Marked downregulation of the granulopoiesis regulator LEF1 is associated with disease progression in the myelodysplastic syndromes

Pellagatti, A., Marafioti, T., Paterson, J. C., Malcovati, L., Della Porta, M. G., Jädersten, M., Pushkaran, B., George, T. I., Arber, D. A., Killick, S., Giagounidis, A., Hellström-Lindberg, E., Cazzola, M., Wainscoat, J. S. & Boultwood, J., Jul 2009, In : British Journal of Haematology. 146, 1, p. 86-90 5 p.

Research output: Contribution to journalArticle

Lymphoid Enhancer-Binding Factor 1
Myelodysplastic Syndromes
Disease Progression
Down-Regulation
Neutropenia

Molecular and clinical features of refractory anemia with ringed sideroblasts associated with marked thrombocytosis

Malcovati, L., Della Porta, M. G., Pietra, D., Boveri, E., Pellagatti, A., Gallì, A., Travaglino, E., Brisci, A., Rumi, E., Passamonti, F., Invernizzi, R., Cremonesi, L., Boultwood, J., Wainscoat, J. S., Hellström-Lindberg, E. & Cazzola, M., 2009, In : Blood. 114, 17, p. 3538-3545 8 p.

Research output: Contribution to journalArticle

Refractory Anemia
Thrombocytosis
Refractory materials
Granulocytes
Platelets

P015 European LeukemiaNet registry programme for low/INT-1 IPSS score myelodysplastic syndromes

Bowen, D., Droste, J., Smith, A., Fenaux, P., Symeonidis, A., Sanz, G., Hellström-Lindberg, E., Cermak, J., Gologan, R., Germing, U., Stauder, R., Malcovati, L. & de Witte, T., May 2009, In : Leukemia Research. 33, SUPPL. 1

Research output: Contribution to journalArticle

P036 Diagnostic utility of flow cytometry in myelodysplastic syndromes lacking conventional diagnostic markers: a prospective validation study

Ogata, K., Della Porta, M., Malcovati, L., Picone, C., Yokose, N., Matsuda, A., Yamashita, T., Tamura, H., Tsukada, J., Dan, K. & Cazzola, M., May 2009, In : Leukemia Research. 33, SUPPL. 1

Research output: Contribution to journalArticle

Erythrocyte Transfusion
Myelodysplastic Syndromes
Cell- and Tissue-Based Therapy
Iron
Chelation Therapy

Standardization of flow cytometry in myelodysplastic syndromes: Report from the first European LeukemiaNet working conference on flow cytometry in myelodysplastic syndromes

Van De Loosdrecht, A. A., Alhan, C., Béné, M. C., Della Porta, M. G., Dräger, A. M., Feuillard, J., Font, P., Germing, U., Haase, D., Homburg, C. H., Ireland, R., Jansen, J. H., Kern, W., Malcovati, L., Te Marvelde, J. G., Mufti, G. J., Ogata, K., Orfao, A., Ossenkoppele, G. J., Porwit, A. & 12 others, Preijers, F. W., Richards, S. J., Schuurhuis, G. J., Subirá, D., Valent, P., Van Der Velden, V. H. J., Vyas, P., Westra, A. H., De Witte, T. M., Wells, D. A., Loken, M. R. & Westers, T. M., Aug 2009, In : Haematologica. 94, 8, p. 1124-1134 11 p.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
Flow Cytometry
Hematopoietic Stem Cells
Granulocyte Precursor Cells
Immunophenotyping

YI1 Gene expression profiling of day 7 erythroblasts from refractory anemia with ringed sideroblasts (RARS) and microarray-based identification of erythroid granulocyte-CSF (G-CSF) targets

Nikpour, M., Pellagatti, A., Liu, A., Karimi, M., Malcovati, L., Forsblom, A. M., Gogvadze, V., Wainscoat, J. S., Cazzola, M., Zhivotovsky, B., Grandien, A., Boultwood, J. & Hellström-Lindberg, E., May 2009, In : Leukemia Research. 33, SUPPL. 1

Research output: Contribution to journalArticle

2008

Biological and clinical relevance of matrix metalloproteinases 2 and 9 in acute myeloid leukaemias and myelodysplastic syndromes

Travaglino, E., Benatti, C., Malcovati, L., Porta, M. G. D., Gallì, A., Bonetti, E., Rosti, V., Cazzola, M. & Invernizzi, R., Mar 2008, In : European Journal of Haematology. 80, 3, p. 216-226 11 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 2
Myelodysplastic Syndromes
Matrix Metalloproteinase 9
Matrix Metalloproteinases
Acute Myeloid Leukemia

Erythropoietin and granulocyte-colony stimulating factor treatment associated with improved survival in myelodysplastic syndrome

Jädersten, M., Malcovati, L., Dybedal, I., Della Porta, M. G., Invernizzi, R., Montgomery, S. M., Pascutto, C., Porwit, A., Cazzola, M. & Hellström-Lindberg, E., 2008, In : Journal of Clinical Oncology. 26, 21, p. 3607-3613 7 p.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
Granulocyte Colony-Stimulating Factor
Erythropoietin
Survival
Karyotype

Genome-wide analysis of copy number changes and loss of heterozygosity in myelodysplastic syndrome with del(5q) using high-density single nucleotide polymorphism arrays

Wang, L., Fidler, C., Nadig, N., Giagounidis, A., Porta, M. G. D., Malcovati, L., Killick, S., Gattermann, N., Aul, C., Boultwood, J. & Wainscoat, J. S., Jul 2008, In : Haematologica. 93, 7, p. 994-1000 7 p.

Research output: Contribution to journalArticle

Uniparental Disomy
Loss of Heterozygosity
Myelodysplastic Syndromes
Single Nucleotide Polymorphism
Genome

Haploinsufficiency of RPS14 in 5q- syndrome is associated with deregulation of ribosomal- and translation-related genes

Pellagatti, A., Hellström-Lindberg, E., Giagounidis, A., Perry, J., Malcovati, L., Della Porta, M. G., Jädersten, M., Killick, S., Fidler, C., Cazzola, M., Wainscoat, J. S. & Boultwood, J., Jul 2008, In : British Journal of Haematology. 142, 1, p. 57-64 8 p.

Research output: Contribution to journalArticle

Haploinsufficiency
Genes
Diamond-Blackfan Anemia
Refractory Anemia
Myelodysplastic Syndromes

Immunophenotypic, cytogenetic and functional characterization of circulating endothelial cells in myelodysplastic syndromes

Della Porta, M. G., Malcovati, L., Rigolin, G. M., Rosti, V., Bonetti, E., Travaglino, E., Boveri, E., Gallì, A., Boggi, S., Ciccone, M., Pramparo, T., Mazzini, G., Invernizzi, R., Lazzarino, M. & Cazzola, M., Mar 2008, In : Leukemia. 22, 3, p. 530-537 8 p.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
Cytogenetics
Endothelial Cells
Flow Cytometry

In reply

Malcovati, L., Cazzola, M. & Germing, U., Mar 1 2008, In : Journal of Clinical Oncology. 26, 7, p. 1181-1182 2 p.

Research output: Contribution to journalArticle

Myelodysplastic/myeloproliferative disorders

Malcovati, L. & Cazzola, M., Jan 2008, In : Haematologica. 93, 1, p. 4-6 3 p.

Research output: Contribution to journalArticle

Myelodysplastic syndromes: Diagnosis and staging

Malcovati, L. & Nimer, S. D., Oct 2008, In : Cancer Control. 15, 4 SUPPL., p. 4-13 10 p.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
Acute Myeloid Leukemia
Erythrocyte Transfusion
Survival
Hematopoiesis

Prognostic relevance of anemia in myelodysplastic syndromes

Cazzola, M. & Malcovati, L., Oct 2008, In : American Journal of Hematology. 83, 10, p. 761-762 2 p.

Research output: Contribution to journalArticle

Supportive care, growth factors, and new therapies in myelodysplastic syndromes

Hellström-Lindberg, E. & Malcovati, L., Mar 2008, In : Blood Reviews. 22, 2, p. 75-91 17 p.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
Intercellular Signaling Peptides and Proteins
decitabine
Therapeutics
Hemoglobins

Supportive Care and Use of Hematopoietic Growth Factors in Myelodysplastic Syndromes

Hellström-Lindberg, E. & Malcovati, L., Jan 2008, In : Seminars in Hematology. 45, 1, p. 14-22 9 p.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
Intercellular Signaling Peptides and Proteins
Therapeutics
Antilymphocyte Serum
Granulocyte Colony-Stimulating Factor

The role of the iron transporter ABCB7 in Refractory Anemia with Ring Sideroblasts

Boultwood, J., Pellagatti, A., Nikpour, M., Pushkaran, B., Fidler, C., Cattan, H., Littlewood, T. J., Malcovati, L., Della Porta, M. G., Jädersten, M., Killick, S., Giagounidis, A., Bowen, D., Hellström-Lindberg, E., Cazzola, M. & Wainscoat, J. S., Apr 9 2008, In : PLoS One. 3, 4, e1970.

Research output: Contribution to journalArticle

Refractory Anemia
Refractory materials
anemia
transporters
erythroblasts

WHO classification and WPSS predict posttransplantation outcome in patients with myelodysplastic syndrome: A study from the Gruppo Italiano Trapianto di Midollo Osseo (GITMO)

Alessandrino, E. P., Della Porta, M. G., Bacigalupo, A., Van Lint, M. T., Falda, M., Onida, F., Bernardi, M., Lori, A. P., Rambaldi, A., Cerretti, R., Marenco, P., Pioltelli, P., Malcovati, L., Pascutto, C., Oneto, R., Fanin, R. & Bosi, A., Aug 1 2008, In : Blood. 112, 3, p. 895-902 8 p.

Research output: Contribution to journalArticle

Refractory Anemia with Excess of Blasts
Myelodysplastic Syndromes
Refractory materials
Health
Refractory Anemia
2007

Gene expression profiling of CD34 + cells in patients with the 5q- syndrome

Boultwood, J., Pellagatti, A., Cattan, H., Lawrie, C. H., Giagounidis, A., Malcovati, L., Porta, M. G. D., Jädersten, M., Killick, S., Fidler, C., Cazzola, M., Hellström-Lindberg, E. & Wainscoat, J. S., Nov 2007, In : British Journal of Haematology. 139, 4, p. 578-589 12 p.

Research output: Contribution to journalArticle

Gene Expression Profiling
Chromosome Mapping
Transcriptome
Genes
Eukaryotic Small Ribosome Subunits
Iron Overload
Myelodysplastic Syndromes
Survival
Ferritins
Iron

Reduced hypoxic ventilatory response with preserved blood oxygenation in yoga trainees and Himalayan Buddhist monks at altitude: Evidence of a different adaptive strategy?

Bernardi, L., Passino, C., Spadacini, G., Bonfichi, M., Arcaini, L., Malcovati, L., Bandinelli, G., Schneider, A., Keyl, C., Feil, P., Greene, R. E. & Bernasconi, C., Mar 2007, In : European Journal of Applied Physiology. 99, 5, p. 511-518 8 p.

Research output: Contribution to journalArticle

Yoga
Erythrocyte Count
Hematocrit
Population Groups
Ventilation

Time-dependent prognostic scoring system for predicting survival and leukemic evolution in myelodysplastic syndromes

Malcovati, L., Germing, U., Kuendgen, A., Della Porta, M. G., Pascutto, C., Invernizzi, R., Giagounidis, A., Hildebrandt, B., Bernasconi, P., Knipp, S., Strupp, C., Lazzarino, M., Aul, C. & Cazzola, M., Aug 10 2007, In : Journal of Clinical Oncology. 25, 23, p. 3503-3510 8 p.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
Survival
Hematology
Karyotype
Proportional Hazards Models
2006

Effects of heparins on hemostatic properties of vascular endothelium.

Della Porta, M. G. & Malcovati, L., Feb 2006, In : Haematologica. 91, 2

Research output: Contribution to journalArticle

Erratum: Genetic and clinical heterogeneity of ferroportin disease (British Journal of Haematology (2005) 131, (663-670))

Cremonesi, L., Forni, G. L., Soriani, N., Lamagna, M., Fermo, I., Daraio, F., Galli, A., Pietra, D., Malcovati, L., Ferrari, M., Camaschella, C. & Cazzola, M., Mar 2006, In : British Journal of Haematology. 132, 6, p. 806 1 p.

Research output: Contribution to journalArticle

Flow cytometry evaluation of erythroid dysplasia in patients with myelodysplastic syndrome

Della Porta, M. G., Malcovati, L., Invernizzi, R., Travaglino, E., Pascutto, C., Maffioli, M., Gallí, A., Boggi, S., Pietra, D., Vanelli, L., Marseglia, C., Levi, S., Arosio, P., Lazzarino, M. & Cazzola, M., Apr 2006, In : Leukemia. 20, 4, p. 549-555 7 p.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
Apoferritins
Flow Cytometry
Sideroblastic Anemia
Erythroblasts

Gene expression profiles of CD34+ cells in myelodysplastic syndromes: Involvement of interferon-stimulated genes and correlation to FAB subtype and karyotype

Pellagatti, A., Cazzola, M., Giagounidis, A. A. N., Malcovati, L., Della Porta, M. G., Killick, S., Campbell, L. J., Wang, L., Langford, C. F., Fidler, C., Oscier, D., Aul, C., Wainscoat, J. S. & Boultwood, J., Jul 1 2006, In : Blood. 108, 1, p. 337-345 9 p.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
Karyotype
Transcriptome
Gene expression
Interferons

Novel homeobox gene recombination in T-cell acute lymphoblastic leukemia

Malcovati, L., Mar 2006, In : Haematologica. 91, 3, p. 290-291 2 p.

Research output: Contribution to journalArticle

Predicting survival and leukemic evolution in patients with myelodysplastic syndrome

Malcovati, L., Della Porta, M. G. & Cazzola, M., Dec 2006, In : Haematologica. 91, 12, p. 1588-1590 3 p.

Research output: Contribution to journalArticle

Myeloproliferative Disorders
Granulocytes
Blood
Chemical activation
Mutation

Survivin expression, apoptosis and proliferation in chronic myelomonocytic leukemia

Invernizzi, R., Travaglino, E., Benatti, C., Malcovati, L., Porta, M. D., Cazzola, M. & Ascari, E., Jun 2006, In : European Journal of Haematology. 76, 6, p. 494-501 8 p.

Research output: Contribution to journalArticle

Leukemia, Myelomonocytic, Chronic
Apoptosis
Myeloproliferative Disorders
Acute Myeloid Leukemia
Myelodysplastic Syndromes
2005

Detection of minimal residual disease in acute lymphoblastic leukemia

Della Porta, M. G. & Malcovati, L., Nov 2005, In : Haematologica. 90, 11, p. 1445-1446 2 p.

Research output: Contribution to journalArticle

Flow cytometry evaluation of erythroid and myeloid dysplasia in patients with myelodysplastic syndrome

Malcovati, L., Della Porta, M. G., Lunghi, M., Pascutto, C., Vanelli, L., Travaglino, E., Maffioli, M., Bernasconi, P., Lazzarino, M., Invernizzi, R. & Cazzola, M., May 2005, In : Leukemia. 19, 5, p. 776-783 8 p.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
Flow Cytometry
Erythroid Cells
Bone Marrow

Genetic and clinical heterogeneity of ferroportin disease

Cemonesi, L., Forni, G. L., Soriani, N., Lamagna, M., Fermo, I., Daraio, F., Galli, A., Pietra, D., Malcovati, L., Ferrari, M., Camaschella, C. & Cazzola, M., Dec 2005, In : British Journal of Haematology. 131, 5, p. 663-670 8 p.

Research output: Contribution to journalArticle

Genetic Heterogeneity
Mutation
Iron Overload
Hepcidins
Exons

Myelodysplastic syndromes - Coping with ineffective hematopoiesis

Cazzola, M. & Malcovati, L., Feb 10 2005, In : New England Journal of Medicine. 352, 6, p. 536-538 3 p.

Research output: Contribution to journalArticle

Prognostic factors and life expectancy in myelodysplastic syndromes classified according to WHO criteria: A basis for clinical decision making

Malcovati, L., Della Porta, M. G., Pascutto, C., Invernizzi, R., Boni, M., Travaglino, E., Passamonti, F., Arcaini, L., Maffioli, M., Bernasconi, P., Lazzarino, M. & Cazzola, M., 2005, In : Journal of Clinical Oncology. 23, 30, p. 7594-7603 10 p.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
Life Expectancy
Survival
Refractory Anemia with Excess of Blasts
Refractory Anemia

PRV-1 and its correlation with treatments and disease status in 210 patients with polycythemia vera and essential thrombocythemia [9]

Passamonti, F., Pietra, D., Rumi, E., Arcaini, L., Della Porta, M. G., Malcovati, L., Pascutto, C., Lazzarino, M. & Cazzola, M., May 2005, In : Leukemia. 19, 5, p. 888-889 2 p.

Research output: Contribution to journalArticle