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20002019
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Research Output 2000 2019

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2000

Hereditary hemochromatosis in a patient with congenital dyserythropoietic anemia

Fargion, S., Valenti, L., Fracanzani, A. L., Sampierto, M., Cappellni, M. D., Scaccabarozzi, A., Soligo, D., Mariani, C. & Fiorelli, G., Nov 15 2000, In : Blood. 96, 10, p. 3653-3655 3 p.

Research output: Contribution to journalArticle

Congenital Dyserythropoietic Anemia
Hemochromatosis
Iron Overload
Iron
Phlebotomy

Hereditary hemochromatosis in a patient with congenital dyserythropoietic anemia

Fargion, S., Valenti, L., Fracanzani, A. L., Sampietro, M., Cappellini, M. D., Scaccabarozzi, A., Soligo, D., Mariani, C. & Fiorelli, G., 2000, In : Blood. 96, 11 PART II

Research output: Contribution to journalArticle

Congenital Dyserythropoietic Anemia
Hemochromatosis
Iron Overload
Iron
Anemia

Relationship between TNFa and iron metabolism in differentiating human monocytic THP-1 cells

Scaccabarozzi, A., Arosio, P., Weiss, G., Valenti, L., Dongiovanni, P., Fracanzani, A. L., Mattioli, M., Levi, S., Fiorelli, G. & Fargion, S., 2000, In : Blood. 96, 11 PART II

Research output: Contribution to journalArticle

Metabolism
Iron
Tumor Necrosis Factor-alpha
Tetradecanoylphorbol Acetate
Apoferritins

Relationship between TNF-α and iron metabolism in differentiating human monocytic THP-1 cells

Scaccabarozzi, A., Arosio, P., Weiss, G., Valenti, L., Dongiovanni, P., Francanzani, A. L., Mattioli, M., Levi, S., Fiorelli, G. & Fargion, S., 2000, In : British Journal of Haematology. 110, 4, p. 978-984 7 p.

Research output: Contribution to journalArticle

Iron
Tumor Necrosis Factor-alpha
Acetates
Apoferritins
Deferoxamine

TNFα and hereditary hemocromatosis: Possible interactions

Valenti, L., Fracanzani, A. L., Scaccabarozzi, A., Dongiovanni, P., Santorelli, G., Fiorelli, G. & Fargion, S., 2000, In : Blood. 96, 11 PART II

Research output: Contribution to journalArticle

Hemochromatosis
Tumor Necrosis Factor-alpha
Iron
Macrophages
Monocytes
2001

Hyperferritinemia, iron overload, and multiple metabolic alterations identify patients at risk for nonalcoholic steatohepatitis

Fargion, S., Mattioli, M., Fracanzani, A. L., Sampietro, M., Tavazzi, D., Fociani, P., Taioli, E., Valenti, L. & Fiorelli, G., 2001, In : American Journal of Gastroenterology. 96, 8, p. 2448-2455 8 p.

Research output: Contribution to journalArticle

Iron Overload
Transferrin
Ferritins
Liver
Insulin Resistance

Tumor necrosis factor α promoter polymorphisms influence the phenotypic expression of hereditary hemochromatosis

Fargion, S., Valenti, L., Dongiovanni, P., Scaccabarozzi, A., Fracanzani, A. L., Taioli, E., Mattioli, M., Sampietro, M. & Fiorelli, G., Jun 15 2001, In : Blood. 97, 12, p. 3707-3712 6 p.

Research output: Contribution to journalArticle

Hemochromatosis
Polymorphism
Tumor Necrosis Factor-alpha
Siderosis
Homozygote
2002

Tumor necrosis factor α promoter polymorphisms and insulin resistance in nonalcoholic fatty liver disease

Valenti, L., Fracanzani, A. L., Dongiovanni, P., Santorelli, G., Branchi, A., Taioli, E., Fiorelli, G. & Fargion, S., 2002, In : Gastroenterology. 122, 2, p. 274-280 7 p.

Research output: Contribution to journalArticle

Insulin Resistance
Tumor Necrosis Factor-alpha
Fatty Liver
Non-alcoholic Fatty Liver Disease
Glucose Intolerance
2003

Effect of iron depletion in patients with nonalcoholic fatty liver disease without carbohydrate intolerance [4] (multiple letters)

Valenti, L., Fracanzani, A. L., Fargion, S., Facchini, F., Hua, N. & Stoohs, R., Mar 1 2003, In : Gastroenterology. 124, 3, p. 866-867 2 p.

Research output: Contribution to journalArticle

Increased susceptibility to nonalcoholic fatty liver disease in heterozygotes for the mutation responsible for hereditary hemochromatosis

Valenti, L., Dongiovanni, P., Fracanzani, A. L., Santorelli, G., Fatta, E., Bertelli, C., Taioli, E., Fiorelli, G. & Fargion, S., Mar 2003, In : Digestive and Liver Disease. 35, 3, p. 172-178 7 p.

Research output: Contribution to journalArticle

Hemochromatosis
Heterozygote
Mutation
Iron Overload
Insulin

What is the contribution of differences in three measures of tumor necrosis factor-alpha activity to insulin resistance in healthy volunteers?

Zavaroni, I., Numeroso, F., Dongiovanni, P., Ardigò, D., Valenti, L., Fracanzani, A. L., Valtuen̂a, S., Delsignore, R., Fargion, S. & Reaven, G. M., Dec 2003, In : Metabolism. 52, 12, p. 1593-1596 4 p.

Research output: Contribution to journalArticle

Insulin Resistance
Healthy Volunteers
Tumor Necrosis Factor-alpha
Insulin
Receptors, Tumor Necrosis Factor, Type II
2004

Coeliac disease and non-alcoholic fatty liver disease (multiple letters) [1]

Marignani, M., Angeletti, S., Ruggeri, M., Cassetta, S., Delle Fave, G., Bardella, M. T., Valenti, L., Pagliari, C., Peracchi, M., Farè, M., Fracanzani, A. L. & Fargion, S., Nov 2004, In : Digestive and Liver Disease. 36, 11, p. 781-782 2 p.

Research output: Contribution to journalArticle

Cytotoxic T-lymphocyte antigen-4 A49G polymorphism is associated with susceptibility to and severity of alcoholic liver disease in Italian patients

Valenti, L., De Feo, T., Fracanzani, A. L., Fatta, E., Salvagnini, M., Aricò, S., Rossi, G., Fiorelli, G. & Fargion, S., Jul 2004, In : Alcohol and Alcoholism. 39, 4, p. 276-280 5 p.

Research output: Contribution to journalArticle

CTLA-4 Antigen
Alcoholic Liver Diseases
Polymorphism
Liver
Fibrosis

Searching for coeliac disease in patients with non-alcoholic fatty liver disease

Bardella, M. T., Valenti, L., Pagliari, C., Peracchi, M., Farè, M., Fracanzani, A. L. & Fargion, S., May 2004, In : Digestive and Liver Disease. 36, 5, p. 333-336 4 p.

Research output: Contribution to journalArticle

Celiac Disease
Fatty Liver
Anti-Idiotypic Antibodies
Liver
Endoscopy

The mitochondrial superoxide dismutase A16V polymorphism in the cardiomyopathy associated with hereditary haemochromatosis

Valenti, L., Conte, D., Piperno, A., Dongiovanni, P., Fracanzani, A. L., Fraquelli, M., Vergani, A., Gianni, C., Carmagnola, L. & Fargion, S., Dec 2004, In : Journal of Medical Genetics. 41, 12, p. 946-950 5 p.

Research output: Contribution to journalArticle

Hemochromatosis
Cardiomyopathies
Superoxide Dismutase
Iron Overload
Hypogonadism

TNFalpha promoter polymorphisms.

Fargion, S., Valenti, L., Dongiovanni, P. & Fracanzani, A. L., 2004, In : Methods in molecular medicine. 98, p. 47-58 12 p.

Research output: Contribution to journalArticle

Tumor Necrosis Factor-alpha
Polymerase Chain Reaction
Base Pair Mismatch
Agar Gel Electrophoresis
Restriction Fragment Length Polymorphisms

Treatment choices for people infected with HCV

Fargion, S., Fracanzani, A. L. & Valenti, L., May 2004, In : Journal of Antimicrobial Chemotherapy. 53, 5, p. 708-712 5 p.

Research output: Contribution to journalArticle

Hepacivirus
Serine Proteinase Inhibitors
Ribavirin
Virus Diseases
Chronic Hepatitis

Turning up the heat in the fat cell

Accili, D. & Valenti, L., Nov 2004, In : Nature Medicine. 10, 11, p. 1168-1169 2 p.

Research output: Contribution to journalArticle

Adipocytes
Obesity
Hot Temperature
Fats
Proteins
2005

Association between heterozygosity for HFE gene mutations and hepatitis viruses in hepatocellular carcinoma

Fracanzani, A. L., Fargion, S., Stazi, M. A., Valenti, L., Amoroso, P., Cariani, E., Sangiovanni, A., Tommasini, M., Rossini, A., Bertelli, C., Fatta, E., Patriarca, V., Brescianini, S. & Stroffolini, T., Jul 2005, In : Blood cells, molecules & diseases. 35, 1, p. 27-32 6 p.

Research output: Contribution to journalArticle

Hepatitis Viruses
Hepatocellular Carcinoma
Mutation
Hepatitis B virus
Hepacivirus

Erratum: Turning up the heat in the fat cell (Nature Medicine (2004) 10 (1168-1169))

Accili, D. & Valenti, L., Jun 2005, In : Nature Medicine. 11, 6, p. 690 1 p.

Research output: Contribution to journalArticle

Iron and insulin resistance

Fargion, S., Dongiovanni, P., Guzzo, A., Colombo, S., Valenti, L. & Fracanzani, A. L., Nov 2005, In : Alimentary Pharmacology and Therapeutics, Supplement. 22, 2, p. 61-63 3 p.

Research output: Contribution to journalArticle

Insulin Resistance
Iron
Insulin
Insulin Receptor
Hepatocytes

Nuclear trapping of the forkhead transcription factor FoxO1 via sirt-dependent deacetylation promotes expression of glucogenetic genes

Frescas, D., Valenti, L. & Accili, D., May 27 2005, In : Journal of Biological Chemistry. 280, 21, p. 20589-20595 7 p.

Research output: Contribution to journalArticle

Forkhead Transcription Factors
Sirtuins
Genes
Chemical activation
Gene Expression

Retraction: Turning up the heat in the fat cell.

Accili, D. & Valenti, L., Jun 2005, In : Nature Medicine. 11, 6, p. 690 1 p.

Research output: Contribution to journalArticle

TNFα genotype affects TNFα release, insulin sensitivity and the severity of liver disease in HCV chronic hepatitis

Valenti, L., Pulixi, E., Fracanzani, A. L., Dongiovanni, P., Maggioni, M., Orsatti, A., Gianni, C. & Fargion, S., Dec 2005, In : Journal of Hepatology. 43, 6, p. 944-950 7 p.

Research output: Contribution to journalArticle

Chronic Hepatitis
Insulin Resistance
Liver Diseases
Genotype
Fatty Liver
2006

Circulating ghrelin levels in patients with inflammatory bowel disease [1]

Peracchi, M., Bardella, M. T., Caprioli, F., Massironi, S., Conte, D., Valenti, L., Ronchi, C., Beck-Peccoz, P., Arosio, M. & Piodi, L., Mar 2006, In : Gut. 55, 3, p. 432-433 2 p.

Research output: Contribution to journalArticle

α1-antitrypsin mutations in NAFLD: High prevalence and association with altered iron metabolism but not with liver damage

Valenti, L., Dongiovanni, P., Piperno, A., Fracanzani, A. L., Maggioni, M., Rametta, R., Loria, P., Casiraghi, M. A., Suigo, E., Ceriani, R., Remondini, E., Trombini, P. & Fargion, S., Oct 2006, In : Hepatology. 44, 4, p. 857-864 8 p.

Research output: Contribution to journalArticle

Iron
Mutation
Liver
Genotype
Ferritins
2007

HFE gene mutations and oxidative stress influence serum ferritin, associated with vascular damage, in hemodialysis patients

Valenti, L., Valenti, G., Como, G., Burdick, L., Santorelli, G., Dongiovanni, P., Rametta, R., Bamonti, F., Novembrino, C., Fracanzani, A. L., Messa, P. G. & Fargion, S., Mar 2007, In : American Journal of Nephrology. 27, 1, p. 101-107 7 p.

Research output: Contribution to journalArticle

Ferritins
Blood Vessels
Renal Dialysis
Oxidative Stress
Iron
Phlebotomy
Ferritins
Insulin Resistance
Case-Control Studies
Iron

Relative contribution of iron genes, dysmetabolism and hepatitis C virus (HCV) in the pathogenesis of altered iron regulation in HCV chronic hepatitis

Valenti, L., Pulixi, E. A., Arosio, P., Cremonesi, L., Biasiotto, G., Dongiovanni, P., Maggioni, M., Fargion, S. & Fracanzani, A. L., Aug 2007, In : Haematologica. 92, 8, p. 1037-1042 6 p.

Research output: Contribution to journalArticle

Chronic Hepatitis
Hepacivirus
Iron
Hepcidins
Mutation

Carotid Artery Intima-media Thickness in Nonalcoholic Fatty Liver Disease

Fracanzani, A. L., Burdick, L., Raselli, S., Pedotti, P., Grigore, L., Santorelli, G., Valenti, L., Maraschi, A., Catapano, A. & Fargion, S., Jan 2008, In : American Journal of Medicine. 121, 1, p. 72-78 7 p.

Research output: Contribution to journalArticle

Carotid Intima-Media Thickness
Carotid Arteries
Liver Function Tests
Blood Vessels
Case-Control Studies

HFE genotype influences erythropoiesis support requirement in hemodialysis patients: A prospective study

Valenti, L., Valenti, G., Como, G., Santorelli, G., Dongiovanni, P., Rametta, R., Fracanzani, A. L., Tavazzi, D., Messa, P. G. & Fargion, S., Jan 2008, In : American Journal of Nephrology. 28, 2, p. 311-316 6 p.

Research output: Contribution to journalArticle

Erythropoiesis
Renal Dialysis
Iron
Genotype
Prospective Studies

HFE mutations in nonalcoholic fatty liver disease

Valenti, L., Dongiovanni, P., Fracanzani, A. L. & Fargion, S., May 2008, In : Hepatology. 47, 5, p. 1794-1795 2 p.

Research output: Contribution to journalArticle

Increased expression and activity of the transcription factor FOXO1 in nonalcoholic steatohepatitis

Valenti, L., Rametta, R., Dongiovanni, P., Maggioni, M., Fracanzani, A. L., Zappa, M., Lattuada, E., Roviaro, G. & Fargion, S., May 2008, In : Diabetes. 57, 5, p. 1355-1362 8 p.

Research output: Contribution to journalArticle

Fatty Liver
Transcription Factors
Insulin Resistance
Glucose-6-Phosphatase
Catalytic Domain
Deferoxamine
Hepatocellular Carcinoma
Up-Regulation
Iron
Hypoxia-Inducible Factor 1

Iron genes, dysmetabolism and fibrosis in chronic hepatitis C

Valenti, L., Dongiovanni, P., Fargion, S. & Fracanzani, A. L., Mar 2008, In : Journal of Hepatology. 48, 3, p. 513-514 2 p.

Research output: Contribution to journalArticle

Reply

Fracanzani, A. L., Valenti, L. & Fargion, S., 2008, In : Hepatology. 48, 6, p. 2088 1 p.

Research output: Contribution to journalArticle

Risk of severe liver disease in nonalcoholic fatty liver disease with normal aminotransferase levels: A role for insulin resistance and diabetes

Fracanzani, A. L., Valenti, L., Bugianesi, E., Andreoletti, M., Colli, A., Vanni, E., Bertelli, C., Fatta, E., Bignamini, D., Marchesini, G. & Fargion, S., Sep 2008, In : Hepatology. 48, 3, p. 792-798 7 p.

Research output: Contribution to journalArticle

Transaminases
Alanine Transaminase
Insulin Resistance
Liver Diseases
Odds Ratio

The hand arthropathy of hereditary hemochromatosis is strongly associated with iron overload

Valenti, L., Fracanzani, A. L., Rossi, V., Rampini, C., Pulixi, E., Varenna, M., Fargion, S. & Sinigaglia, L., Jan 2008, In : Journal of Rheumatology. 35, 1, p. 153-158 6 p.

Research output: Contribution to journalArticle

Iron Overload
Hemochromatosis
Joint Diseases
Hand
Ferritins
2009

Association between iron overload and osteoporosis in patients with hereditary hemochromatosis

Valenti, L., Varenna, M., Fracanzani, A. L., Rossi, V., Fargion, S. & Sinigaglia, L., Apr 2009, In : Osteoporosis International. 20, 4, p. 549-555 7 p.

Research output: Contribution to journalArticle

Iron Overload
Hemochromatosis
Osteoporosis
Hypogonadism
Spine
Iron Overload
Liver Transplantation
Recurrence
Liver
Siderosis

HFE mutations modulate the effect of iron on serum hepcidin-25 in chronic hemodialysis patients

Valenti, L., Girelli, D., Valenti, G. F., Castagna, A., Como, G., Campostrini, N., Rametta, R., Dongiovanni, P., Messa, P. & Fargion, S., 2009, In : Clinical Journal of the American Society of Nephrology. 4, 8, p. 1331-1337 7 p.

Research output: Contribution to journalArticle

Hepcidins
Renal Dialysis
Iron
Mutation
Serum

Reply

Fracanzani, A. L., Valenti, L. & Fargion, S., 2009, In : Hepatology. 49, 2, p. 697 1 p.

Research output: Contribution to journalArticle

Alcoholic Fatty Liver
Liver Diseases
Immune System
Alcoholic Liver Diseases
Lipogenesis
2010

A promoter polymorphism in the liver-specific fatty acid transport protein 5 is associated with features of the metabolic syndrome and steatosis

Auinger, A., Valenti, L., Pfeuffer, M., Helwig, U., Herrmann, J., Fracanzani, A. L., Dongiovanni, P., Fargion, S., Schrezenmeir, J. & Rubin, D., 2010, In : Hormone and Metabolic Research. 42, 12, p. 854-859 6 p.

Research output: Contribution to journalArticle

Fatty Acid Transport Proteins
Polymorphism
Liver
Alleles
Insulin
Siderosis
beta-Globins
Fibrosis
Iron
beta-Thalassemia

Genetic variants regulating insulin receptor signalling are associated with the severity of liver damage in patients with non-alcoholic fatty liver disease

Dongiovanni, P., Valenti, L., Rametta, R., Daly, A. K., Nobili, V., Mozzi, E., Leathart, J. B. S., Pietrobattista, A., Burt, A. D., Maggioni, M., Fracanzani, A. L., Lattuada, E., Zappa, M. A., Roviaro, G., Marchesini, G., Day, C. P. & Fargion, S., Feb 2010, In : Gut. 59, 2, p. 267-273 7 p.

Research output: Contribution to journalArticle

Insulin Receptor
Phosphoric Diester Hydrolases
Insulin Receptor Substrate Proteins
Nucleotides
Liver