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20002019
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Research Output 2000 2019

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Article

A 360-degree overview of paediatric NAFLD: Recent insights

Nobili, V., Svegliati-Baroni, G., Alisi, A., Miele, L., Valenti, L. & Vajro, P., Jun 2013, In : Journal of Hepatology. 58, 6, p. 1218-1229 12 p.

Research output: Contribution to journalArticle

Pediatrics
Obesity
Sedentary Lifestyle
Liver
Fatty Liver
Fatty Liver
Liver
Biopsy
Developed Countries
ROC Curve

Accuracy of imaging methods for steatohepatitis diagnosis in non-alcoholic fatty liver disease patients: A systematic review

Besutti, G., Valenti, L., Ligabue, G., Bassi, M. C., Pattacini, P., Guaraldi, G. & Giorgi Rossi, P., Jan 1 2019, In : Liver International. 39, 8, p. 1521-1534

Research output: Contribution to journalArticle

Fatty Liver
Elasticity Imaging Techniques
Magnetic Resonance Spectroscopy
Acoustics
MEDLINE

Acquired hepatocerebral degeneration (AHD): a peculiar neurological impairment in advanced chronic liver disease

Pigoni, A., Iuculano, F., Saetti, C., Airaghi, L., Burdick, L., Spreafico, S., Curioni, M., Lombardi, R., Valenti, L., Fracanzani, A. L. & Fargion, S., 2018, In : Metabolic Brain Disease. 33, 1, p. 347-352 6 p.

Research output: Contribution to journalArticle

Hepatolenticular Degeneration
Liver
Liver Diseases
Brain
Chronic Disease

AISF position paper on liver disease and pregnancy

Morisco, F., Bruno, R., Bruno, R., Burra, P., Calvaruso, V., Cannoni, A., Caporaso, N., Caviglia, G. P., Ciancio, A., Fargion, S., Fargion, S., Floreani, A., Gaeta, G. B., Guarino, M., Invernizzi, P., Invernizzi, P., Loguercio, C., Mazzella, G., Petraglia, F., Primignani, M. & 7 others, Primignani, M., Smedile, A., Valenti, L., Valenti, L. V. C., Vannuccini, S., Voltolini, C. & Villao, E., Feb 1 2016, In : Digestive and Liver Disease. 48, 2, p. 120-137 18 p.

Research output: Contribution to journalArticle

Liver Diseases
Pregnancy
Differential Diagnosis
Chronic Disease
Mothers

AISF position paper on liver disease and pregnancy

Morisco, F., Bruno, R., Bruno, R., Burra, P., Calvaruso, V., Cannoni, A., Caporaso, N., Caviglia, G. P., Ciancio, A., Fargion, S., Fargion, S., Floreani, A., Gaeta, G. B., Guarino, M., Invernizzi, P., Invernizzi, P., Loguercio, C., Mazzella, G., Petraglia, F., Primignani, M. & 7 others, Primignani, M., Smedile, A., Valenti, L., Valenti, L. V. C., Vannuccini, S., Voltolini, C. & Villao, E., Feb 1 2016, In : Digestive and Liver Disease. 48, 2, p. 120-137 18 p.

Research output: Contribution to journalArticle

Liver Diseases
Pregnancy
Differential Diagnosis
Chronic Disease
Mothers

AISF position paper on liver disease and pregnancy

Morisco, F., Bruno, R., Bugianesi, E., Burra, P., Calvaruso, V., Cannoni, A., Caporaso, N., Caviglia, G. P., Ciancio, A., Fargion, S., Federico, A., Floreani, A., Gaeta, G. B., Guarino, M., Invernizzi, P., Licata, A., Loguercio, C., Mazzella, G., Petraglia, F., Primignani, M. & 7 others, Rodriguez-Castro, K., Smedile, A., Valenti, L., Vannic, E., Vannuccini, S., Voltolini, C. & Villao, E., Feb 1 2016, In : Digestive and Liver Disease. 48, 2, p. 120-137 18 p.

Research output: Contribution to journalArticle

Liver Diseases
Pregnancy
Differential Diagnosis
Chronic Disease
Mothers

AISF position paper on nonalcoholic fatty liver disease (NAFLD): Updates and future directions

Lonardo, A., Nascimbeni, F., Targher, G., Bernardi, M., Bonino, F., Bugianesi, E., Casini, A., Gastaldelli, A., Marchesini, G., Marra, F., Miele, L., Morisco, F., Petta, S., Piscaglia, F., Svegliati-Baroni, G., Valenti, L. & Bellentani, S., May 1 2017, In : Digestive and Liver Disease. 49, 5, p. 471-483 13 p.

Research output: Contribution to journalArticle

Liver Neoplasms
Fibrosis
Biomarkers
Liver
Metabolic Diseases

A novel alpha1-antitrypsin null variant (PiQ0Milano)

Rametta, R., Nebbia, G., Dongiovanni, P., Farallo, M., Fargion, S. & Valenti, L., 2013, In : World Journal of Hepatology. 5, 8, p. 458-461 4 p.

Research output: Contribution to journalArticle

Pulmonary Emphysema
Incidental Findings
Protein Stability
Lung Diseases
Genes

A population-based study on the prevalence of NASH using scores validated against liver histology

Hyysalo, J., Männistö, V. T., Zhou, Y., Arola, J., Kärjä, V., Leivonen, M., Juuti, A., Jaser, N., Lallukka, S., Käkelä, P., Venesmaa, S., Simonen, M., Saltevo, J., Moilanen, L., Korpi-Hyövalti, E., Keinänen-Kiukaanniemi, S., Oksa, H., Orho-Melander, M., Valenti, L., Fargion, S. & 3 others, Pihlajamäki, J., Peltonen, M. & Yki-Järvinen, H., 2014, In : Journal of Hepatology. 60, 4, p. 839-846 8 p.

Research output: Contribution to journalArticle

Fatty Liver
Histology
Cross-Sectional Studies
Liver
Population

A promoter polymorphism in the liver-specific fatty acid transport protein 5 is associated with features of the metabolic syndrome and steatosis

Auinger, A., Valenti, L., Pfeuffer, M., Helwig, U., Herrmann, J., Fracanzani, A. L., Dongiovanni, P., Fargion, S., Schrezenmeir, J. & Rubin, D., 2010, In : Hormone and Metabolic Research. 42, 12, p. 854-859 6 p.

Research output: Contribution to journalArticle

Fatty Acid Transport Proteins
Polymorphism
Liver
Alleles
Insulin
Iron
Phlebotomy
Alanine Transaminase
Liver
Life Style

Association between Helicobacter pylori infection and risk of nonalcoholic fatty liver disease: An updated meta-analysis

Mantovani, A., Turino, T., Altomari, A., Lonardo, A., Zoppini, G., Valenti, L., Tilg, H., Byrne, C. D. & Targher, G., Jul 1 2019, In : Metabolism: Clinical and Experimental. 96, p. 56-65 10 p.

Research output: Contribution to journalArticle

Helicobacter Infections
Helicobacter pylori
Meta-Analysis
Publication Bias
Longitudinal Studies

Association between heterozygosity for HFE gene mutations and hepatitis viruses in hepatocellular carcinoma

Fracanzani, A. L., Fargion, S., Stazi, M. A., Valenti, L., Amoroso, P., Cariani, E., Sangiovanni, A., Tommasini, M., Rossini, A., Bertelli, C., Fatta, E., Patriarca, V., Brescianini, S. & Stroffolini, T., Jul 2005, In : Blood cells, molecules & diseases. 35, 1, p. 27-32 6 p.

Research output: Contribution to journalArticle

Hepatitis Viruses
Hepatocellular Carcinoma
Mutation
Hepatitis B virus
Hepacivirus

Association between iron overload and osteoporosis in patients with hereditary hemochromatosis

Valenti, L., Varenna, M., Fracanzani, A. L., Rossi, V., Fargion, S. & Sinigaglia, L., Apr 2009, In : Osteoporosis International. 20, 4, p. 549-555 7 p.

Research output: Contribution to journalArticle

Iron Overload
Hemochromatosis
Osteoporosis
Hypogonadism
Spine

Association between PNPLA3rs738409 polymorphism decreased kidney function in postmenopausal type 2 diabetic women with or without non-alcoholic fatty liver disease

Mantovani, A., Zusi, C., Sani, E., Colecchia, A., Lippi, G., Zaza, G. L., Valenti, L., Byrne, C. D., Maffeis, C., Bonora, E. & Targher, G., Jan 1 2019, In : Diabetes and Metabolism. 45, 5, p. 480-487

Research output: Contribution to journalArticle

Chronic Renal Insufficiency
Kidney
Genotype
Albuminuria
Non-alcoholic Fatty Liver Disease

Association between the PNPLA3 (rs738409 C>G) variant and hepatocellular carcinoma: Evidence from a meta-analysis of individual participant data

Trépo, E., Nahon, P., Bontempi, G., Valenti, L., Falleti, E., Nischalke, H. D., Hamza, S., Corradini, S. G., Burza, M. A., Guyot, E., Donati, B., Spengler, U., Hillon, P., Toniutto, P., Henrion, J., Franchimont, D., Devière, J., Mathurin, P., Moreno, C., Romeo, S. & 1 others, Deltenre, P., 2014, In : Hepatology. 59, 6, p. 2170-2177 8 p.

Research output: Contribution to journalArticle

Meta-Analysis
Hepatocellular Carcinoma
Chronic Hepatitis C
Alcoholic Liver Diseases
Odds Ratio

A "systems medicine" approach to the study of non-alcoholic fatty liver disease

Petta, S., Valenti, L. V. C., Bugianesi, E., Targher, G., Bellentani, S., Bonino, F., Fargion, S., Vanni, E., Ferrannini, E., Loguercio, C., Lonardo, A., Marra, F., Mancini, M., Miele, L., Nobili, V., Baroni, G. S., Alessandro, F., Ballestri, S., Brunetto, M. R., Coco, B. & 7 others, Grieco, A., Kondili, L. A., Nascimbeni, F., Prinster, A., Romagnoli, D., Taddei, S. & Vella, S., Mar 1 2016, In : Digestive and Liver Disease. 48, 3, p. 333-342 10 p.

Research output: Contribution to journalArticle

Fatty Liver
Systems Analysis
Translational Medical Research
Systems Biology
Disease Susceptibility

A "systems medicine" approach to the study of non-alcoholic fatty liver disease

Petta, S., Valenti, L., Bugianesi, E., Targher, G., Bellentani, S., Bonino, F., Fargion, S., Vanni, E., Ferrannini, E., Loguercio, C., Lonardo, A., Marra, F., Mancini, M., Miele, L., Nobili, V., Baroni, G. S., Alessandro, F., Ballestri, S., Brunetto, M. R., Coco, B. & 7 others, Grieco, A., Kondili, L., Nascimbeni, F., Prinster, A., Romagnoli, D., Taddei, S. & Vella, S., Mar 1 2016, In : Digestive and Liver Disease. 48, 3, p. 333-342 10 p.

Research output: Contribution to journalArticle

Fatty Liver
Systems Analysis
Translational Medical Research
Systems Biology
Disease Susceptibility

A "systems medicine" approach to the study of non-alcoholic fatty liver disease

Petta, S., Valenti, L. V. C., Bugianesi, E., Targher, G., Bellentani, S., Bonino, F., Fargion, S., Vanni, E., Ferrannini, E., Loguercio, C., Lonardo, A., Marra, F., Mancini, M., Miele, L., Nobili, V., Baroni, G. S., Alessandro, F., Ballestri, S., Brunetto, M. R., Coco, B. & 7 others, Grieco, A., Kondili, L. A., Nascimbeni, F., Prinster, A., Romagnoli, D., Taddei, S. & Vella, S., Mar 1 2016, In : Digestive and Liver Disease. 48, 3, p. 333-342 10 p.

Research output: Contribution to journalArticle

Fatty Liver
Systems Analysis
Translational Medical Research
Systems Biology
Disease Susceptibility

A tetra-primer amplification refractory mutation system polymerase chain reaction for the evaluation of rs12979860 IL28B genotype

Galmozzi, E., Menico, B. D., Rametta, R., Dongiovanni, P., Fracanzani, A. L., Benedan, L., Borroni, V., Maggioni, P., Fargion, S. & Valenti, L., Sep 2011, In : Journal of Viral Hepatitis. 18, 9, p. 628-630 3 p.

Research output: Contribution to journalArticle

Interferons
Single Nucleotide Polymorphism
Genotype
Polymerase Chain Reaction
Mutation
Siderosis
beta-Globins
Fibrosis
Iron
beta-Thalassemia
Iron Overload
Hemochromatosis
Liver Diseases
Chronic Disease
Iron

Building mass to prevent non-alcoholic fatty liver disease?

Pelusi, S. & Valenti, L., Apr 2019, In : Hepatobiliary surgery and nutrition. 8, 2, p. 173-176 4 p.

Research output: Contribution to journalArticle

Carotid Artery Intima-media Thickness in Nonalcoholic Fatty Liver Disease

Fracanzani, A. L., Burdick, L., Raselli, S., Pedotti, P., Grigore, L., Santorelli, G., Valenti, L., Maraschi, A., Catapano, A. & Fargion, S., Jan 2008, In : American Journal of Medicine. 121, 1, p. 72-78 7 p.

Research output: Contribution to journalArticle

Carotid Intima-Media Thickness
Carotid Arteries
Liver Function Tests
Blood Vessels
Case-Control Studies

Causal relationship of hepatic fat with liver damage and insulin resistance in nonalcoholic fatty liver

Dongiovanni, P., Stender, S., Pietrelli, A., Mancina, R. M., Cespiati, A., Petta, S., Pelusi, S., Pingitore, P., Badiali, S., Maggioni, M., Mannisto, V., Grimaudo, S., Pipitone, R. M., Pihlajamaki, J., Craxi, A., Taube, M., Carlsson, L. M. S., Fargion, S., Romeo, S., Kozlitina, J. & 1 others, Valenti, L., Apr 1 2018, In : Journal of Internal Medicine. 283, 4, p. 356-370 15 p.

Research output: Contribution to journalArticle

Insulin Resistance
Fats
Liver
Liver Cirrhosis
Biopsy

CDKN1A: A double-edged sword in fatty liver?

Valenti, L. & Dongiovanni, P., May 1 2014, In : Cell Cycle. 13, 9, p. 1371-1372 2 p.

Research output: Contribution to journalArticle

Characterization and sub-cellular localization of SS1R, SS2R, and SS5R in human late-stage prostate cancer cells: Effect of mono- and bi-specific somatostatin analogs on cell growth

Ruscica, M., Magni, P., Steffani, L., Gatto, F., Albertelli, M., Rametta, R., Valenti, L., Ameri, P., Magnaghi, V., Culler, M. D., Minuto, F., Ferone, D. & Arvigo, M., Feb 15 2014, In : Molecular and Cellular Endocrinology. 382, 2, p. 860-870 11 p.

Research output: Contribution to journalArticle

Cell growth
Somatostatin
Prostatic Neoplasms
Cells
Growth

Circulating ghrelin levels in patients with inflammatory bowel disease [1]

Peracchi, M., Bardella, M. T., Caprioli, F., Massironi, S., Conte, D., Valenti, L., Ronchi, C., Beck-Peccoz, P., Arosio, M. & Piodi, L., Mar 2006, In : Gut. 55, 3, p. 432-433 2 p.

Research output: Contribution to journalArticle

Cirrhosis and rapid virological response to peginterferon plus ribavirin determine treatment outcome in HCV-1 IL28B rs12979860 CC patients

Aghemo, A., Degasperi, E., Rumi, M. G., Galmozzi, E., Valenti, L., De Francesco, R., De Nicola, S., Cheroni, C., Grassi, E. & Colombo, M., 2013, In : BioMed Research International. 2013, 580796.

Research output: Contribution to journalArticle

Ribavirin
Interleukin-1
Viruses
Hepacivirus
Fibrosis

Cobalamin as a regulator of serum and cerebrospinal fluid levels of normal prions

Scalabrino, G., Veber, D., Briani, C., Milani, S., Terralavoro, A., Brenna, S., Valenti, L., Silani, V., Morelli, C. & Peracchi, M., Jan 2013, In : Journal of Clinical Neuroscience. 20, 1, p. 134-138 5 p.

Research output: Contribution to journalArticle

Prions
Vitamin B 12
Cerebrospinal Fluid
Serum
Subacute Combined Degeneration

Coeliac disease and non-alcoholic fatty liver disease (multiple letters) [1]

Marignani, M., Angeletti, S., Ruggeri, M., Cassetta, S., Delle Fave, G., Bardella, M. T., Valenti, L., Pagliari, C., Peracchi, M., Farè, M., Fracanzani, A. L. & Fargion, S., Nov 2004, In : Digestive and Liver Disease. 36, 11, p. 781-782 2 p.

Research output: Contribution to journalArticle

Contribution of a genetic risk score to clinical prediction of hepatic steatosis in obese children and adolescents

Zusi, C., Mantovani, A., Olivieri, F., Morandi, A., Corradi, M., Miraglia Del Giudice, E., Dauriz, M., Valenti, L., Byrne, C. D., Targher, G. & Maffeis, C., Jan 1 2019, In : Digestive and Liver Disease. 51, 11, p. 1586-1592

Research output: Contribution to journalArticle

Liver
Single Nucleotide Polymorphism
Non-alcoholic Fatty Liver Disease
Genetic Loci
Lipid Metabolism

Cytotoxic T-lymphocyte antigen-4 A49G polymorphism is associated with susceptibility to and severity of alcoholic liver disease in Italian patients

Valenti, L., De Feo, T., Fracanzani, A. L., Fatta, E., Salvagnini, M., Aricò, S., Rossi, G., Fiorelli, G. & Fargion, S., Jul 2004, In : Alcohol and Alcoholism. 39, 4, p. 276-280 5 p.

Research output: Contribution to journalArticle

CTLA-4 Antigen
Alcoholic Liver Diseases
Polymorphism
Liver
Fibrosis

Deciphering the role of v3 fatty acids in nonalcoholic steatohepatitis

Valenti, L. & Nobili, V., Oct 8 2014, In : Journal of Pediatric Gastroenterology and Nutrition. 59, 4, p. 423-424 2 p.

Research output: Contribution to journalArticle

Degradation of PHLPP2 by KCTD17, via a Glucagon-Dependent Pathway, Promotes Hepatic Steatosis

Kim, K. J., Ryu, D., Dongiovanni, P., Ozcan, L., Nayak, S., Ueberheide, B., Valenti, L., Auwerx, J. & Pajvani, U. B., Dec 1 2017, In : Gastroenterology. 153, 6, p. 1568-1580.e10

Research output: Contribution to journalArticle

Protein Phosphatase 2
Glucagon
Liver
Obese Mice
Lipogenesis

DEPDC5 variants increase fibrosis progression in Europeans with chronic hepatitis C virus infection

Burza, M. A., Motta, B. M., Mancina, R. M., Pingitore, P., Pirazzi, C., Lepore, S. M., Spagnuolo, R., Doldo, P., Russo, C., Lazzaro, V., Fischer, J., Berg, T., Aghemo, A., Cheroni, C., De Francesco, R., Fargion, S., Colombo, M., Datz, C., Stickel, F., Valenti, L. & 1 others, Romeo, S., Feb 1 2016, In : Hepatology. 63, 2, p. 418-427 10 p.

Research output: Contribution to journalArticle

Chronic Hepatitis C
Virus Diseases
Hepacivirus
Fibrosis
Catenins

Destined to develop NAFLD? The predictors of fatty liver from birth to adulthood

Valenti, L. & Romeo, S., 2016, (Accepted/In press) In : Journal of Hepatology.

Research output: Contribution to journalArticle

Ferritins
Liver
Iron
Therapeutics
Insulin Resistance

Dietary anthocyanins as nutritional therapy for nonalcoholic fatty liver disease

Valenti, L., Riso, P., Mazzocchi, A., Porrini, M., Fargion, S. & Agostoni, C., 2013, In : Oxidative Medicine and Cellular Longevity. 145421.

Research output: Contribution to journalArticle

Anthocyanins
Liver
Fatty Liver
Therapeutics
Lipids

Dietary iron overload induces visceral adipose tissue insulin resistance

Dongiovanni, P., Ruscica, M., Rametta, R., Recalcati, S., Steffani, L., Gatti, S., Girelli, D., Cairo, G., Magni, P., Fargion, S. & Valenti, L., Jun 2013, In : American Journal of Pathology. 182, 6, p. 2254-2263 10 p.

Research output: Contribution to journalArticle

Dietary Iron
Iron Overload
Intra-Abdominal Fat
Insulin Resistance
Iron

DNA methylation profiling of the X chromosome reveals an aberrant demethylation on CXCR3 promoter in primary biliary cirrhosis

Lleo, A., Zhang, W., Zhao, M., Tan, Y., Bernuzzi, F., Zhu, B., Liu, Q., Tan, Q., Malinverno, F., Valenti, L., Jiang, T., Tan, L., Liao, W., Coppel, R., Invernizzi, P., Lu, Q., Adams, D. H. & Gershwin, M. E., Jul 7 2015, In : Clinical Epigenetics. 7, 1, 61.

Research output: Contribution to journalArticle

DNA Fingerprinting
Biliary Liver Cirrhosis
X Chromosome
DNA Methylation
T-Lymphocytes

Early interplay of intra-hepatic iron and insulin resistance in children with non-alcoholic fatty liver disease

Manco, M., Alisi, A., Real, J. M. F., Equitani, F., Devito, R., Valenti, L. & Nobili, V., Sep 2011, In : Journal of Hepatology. 55, 3, p. 647-653 7 p.

Research output: Contribution to journalArticle

Insulin Resistance
Iron
Liver
Siderosis
Mutation

Effect of iron depletion in patients with nonalcoholic fatty liver disease without carbohydrate intolerance [4] (multiple letters)

Valenti, L., Fracanzani, A. L., Fargion, S., Facchini, F., Hua, N. & Stoohs, R., Mar 1 2003, In : Gastroenterology. 124, 3, p. 866-867 2 p.

Research output: Contribution to journalArticle

Effect of the A736V TMPRSS6 polymorphism on the penetrance and clinical expression of hereditary hemochromatosis

Valenti, L., Fracanzani, A. L., Rametta, R., Fraquelli, M., Soverini, G., Pelusi, S., Dongiovanni, P., Conte, D. & Fargion, S., Dec 2012, In : Journal of Hepatology. 57, 6, p. 1319-1325 7 p.

Research output: Contribution to journalArticle

Hemochromatosis
Penetrance
Hepcidins
Genotype
Iron

Epicardial Adipose Tissue (EAT) thickness is associated with cardiovascular and liver damage in nonalcoholic fatty liver disease

Fracanzani, A. L., Pisano, G., Consonni, D., Tiraboschi, S., Baragetti, A., Bertelli, C., Norata, G. D., Dongiovanni, P., Valenti, L., Grigore, L., Tonella, T., Catapano, A. & Fargion, S., Sep 1 2016, In : PLoS One. 11, 9, e0162473.

Research output: Contribution to journalArticle

fatty liver
Liver
adipose tissue
Adipose Tissue
Tissue

Erratum: Turning up the heat in the fat cell (Nature Medicine (2004) 10 (1168-1169))

Accili, D. & Valenti, L., Jun 2005, In : Nature Medicine. 11, 6, p. 690 1 p.

Research output: Contribution to journalArticle