20052019

Research output per year

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Research Output

2019

Effects of Macuprev® Supplementation in Age-Related Macular Degeneration: A Double-Blind Randomized Morpho-Functional Study Along 6 Months of Follow-Up

Parravano, M., Tedeschi, M., Manca, D., Costanzo, E., Di Renzo, A., Giorno, P., Barbano, L., Ziccardi, L., Varano, M. & Parisi, V., Sep 1 2019, In : Advances in Therapy. 36, 9, p. 2493-2505 13 p.

Research output: Contribution to journalArticle

Open Access

Functional Changes of Retinal Ganglion Cells and Visual Pathways in Patients with Chronic Leber's Hereditary Optic Neuropathy during One Year of Follow-up

Parisi, V., Ziccardi, L., Sadun, F., De Negri, A. M., La Morgia, C., Barbano, L., Carelli, V. & Barboni, P., Jul 1 2019, In : Ophthalmology. 126, 7, p. 1033-1044 12 p.

Research output: Contribution to journalArticle

Gene therapy in retinal dystrophies

Ziccardi, L., Cordeddu, V., Gaddini, L., Matteucci, A., Parravano, M., Malchiodi-Albedi, F. & Varano, M., Nov 2 2019, In : International Journal of Molecular Sciences. 20, 22, 5722.

Research output: Contribution to journalReview article

Open Access

Mutation profile of BBS genes in patients with Bardet-Biedl syndrome: an Italian study

Manara, E., Paolacci, S., D'Esposito, F., Abeshi, A., Ziccardi, L., Falsini, B., Colombo, L., Iarossi, G., Pilotta, A., Boccone, L., Guerri, G., Monica, M., Marta, B., Maltese, P. E., Buzzonetti, L., Rossetti, L. & Bertelli, M., Jun 13 2019, In : Italian Journal of Pediatrics. 45, 1, p. 72

Research output: Contribution to journalArticle

Mutation profile of BBS genes in patients with Bardet-Biedl syndrome: an Italian study

Manara, E., Paolacci, S., D'Esposito, F., Abeshi, A., Ziccardi, L., Falsini, B., Colombo, L., Iarossi, G., Pilotta, A., Boccone, L., Guerri, G., Monica, M., Marta, B., Maltese, P. E., Buzzonetti, L., Rossetti, L. & Bertelli, M., Jun 13 2019, In : Ital. J. Pediatr.. 45, 1

Research output: Contribution to journalArticle

Neuroenhancement and neuroprotection by oral solution citicoline in non-arteritic ischemic optic neuropathy as a model of neurodegeneration: A randomized pilot study

Parisi, V., Barbano, L., Di Renzo, A., Coppola, G. & Ziccardi, L., Jan 1 2019, In : PLoS One. 14, 7, e0220435.

Research output: Contribution to journalArticle

Open Access

Pathogenicity of new BEST1 variants identified in Italian patients with best vitelliform macular dystrophy assessed by computational structural biology

Frecer, V., Iarossi, G., Salvetti, A. P., Maltese, P. E., Delledonne, G., Oldani, M., Staurenghi, G., Falsini, B., Minnella, A. M., Ziccardi, L., Magli, A., Colombo, L., D'Esposito, F., Miertus, J., Viola, F., Attanasio, M., Maggio, E. & Bertelli, M., Oct 1 2019, In : Journal of Translational Medicine. 17, 1

Research output: Contribution to journalArticle

Pathogenicity of new BEST1 variants identified in Italian patients with best vitelliform macular dystrophy assessed by computational structural biology

Frecer, V., Iarossi, G., Salvetti, A. P., Maltese, P. E., Delledonne, G., Oldani, M., Staurenghi, G., Falsini, B., Minnella, A. M., Ziccardi, L., Magli, A., Colombo, L., D'Esposito, F., Miertus, J., Viola, F., Attanasio, M., Maggio, E. & Bertelli, M., Oct 1 2019, In : Journal of Translational Medicine. 17, 1, 330.

Research output: Contribution to journalArticle

Open Access

Pathogenicity of new BEST1 variants identified in Italian patients with best vitelliform macular dystrophy assessed by computational structural biology

Frecer, V., Iarossi, G., Salvetti, A. P., Maltese, P. E., Delledonne, G., Oldani, M., Staurenghi, G., Falsini, B., Minnella, A. M., Ziccardi, L., Magli, A., Colombo, L., D'Esposito, F., Miertus, J., Viola, F., Attanasio, M., Maggio, E. & Bertelli, M., Oct 1 2019, In : Journal of Translational Medicine. 17, 1

Research output: Contribution to journalArticle

2018

A novel p.(Glu111Val) missense mutation in GUCA1A associated with cone-rod dystrophy leads to impaired calcium sensing and perturbed second messenger homeostasis in photoreceptors

Marino, V., Dal Cortivo, G., Oppici, E., Maltese, P. E., D'Esposito, F., Manara, E., Ziccardi, L., Falsini, B., Magli, A., Bertelli, M. & Dell'Orco, D., Dec 15 2018, In : Human Molecular Genetics. 27, 24, p. 4204-4217 14 p.

Research output: Contribution to journalArticle

Association between Early Neuroretinal Dysfunction and Peripheral Motor Unit Loss in Patients with Type 1 Diabetes Mellitus

Picconi, F., Mataluni, G., Ziccardi, L., Parravano, M., Di Renzo, A., Ylli, D., Pasqualetti, P., Studer, V., Chioma, L., Marfia, G. A. & Frontoni, S., Oct 4 2018, In : Journal of Diabetes Research. 2018, p. 9763507 9 p.

Research output: Contribution to journalArticle

Central retina functional damage in usher syndrome type 2: 22 years of focal macular ERG analysis in a patient population from central and southern Italy

Galli-Resta, L., Placidi, G., Campagna, F., Ziccardi, L., Piccardi, M., Minnella, A., Abed, E., Iovine, S., Maltese, P., Bertelli, M. & Falsini, B., Aug 1 2018, In : Investigative Ophthalmology and Visual Science. 59, 10, p. 3827-3835 9 p.

Research output: Contribution to journalArticle

Citicoline and retinal ganglion cells: Effects on morphology and function

Parisi, V., Oddone, F., Ziccardi, L., Roberti, G., Coppola, G. & Manni, G., Jan 1 2018, In : Current Neuropharmacology. 16, 7, p. 919-932 14 p.

Research output: Contribution to journalReview article

Early and localized retinal dysfunction in patients with type 1 diabetes mellitus studied by multifocal electroretinogram

Ziccardi, L., Parisi, V., Picconi, F., Di Renzo, A., Lombardo, M., Frontoni, S. & Parravano, M., Nov 1 2018, In : Acta Diabetologica. 55, 11, p. 1191-1200 10 p.

Research output: Contribution to journalArticle

Multimodal Imaging in Autosomal Dominant Cone-Rod Dystrophy Caused by Novel CRX Variant

D'Esposito, F., Cennamo, G., De Crecchio, G., Maltese, P. E., Cecchin, S., Bertelli, M., Ziccardi, L., Esposito Veneruso, P., Magli, A., Cennamo, G. & Cordeiro, M. F., Oct 1 2018, In : Ophthalmic Research. 60, 3, p. 169-175 7 p.

Research output: Contribution to journalArticle

Retinal AAV8-RS1 Gene Therapy for X-Linked Retinoschisis: Initial Findings from a Phase I/IIa Trial by Intravitreal Delivery

Cukras, C., Wiley, H. E., Jeffrey, B. G., Sen, H. N., Turriff, A., Zeng, Y., Vijayasarathy, C., Marangoni, D., Ziccardi, L., Kjellstrom, S., Park, T. K., Hiriyanna, S., Wright, J. F., Colosi, P., Wu, Z., Bush, R. A., Wei, L. L. & Sieving, P. A., Sep 5 2018, In : Molecular Therapy. 26, 9, p. 2282-2294 13 p.

Research output: Contribution to journalArticle

Retinal dysfunction characterizes subtypes of dominant optic atrophy

Cascavilla, M. L., Parisi, V., Triolo, G., Ziccardi, L., Borrelli, E., Di Renzo, A., Balducci, N., Lamperti, C., Bianchi Marzoli, S., Darvizeh, F., Sadun, A. A., Carelli, V., Bandello, F. & Barboni, P., 2018, In : Acta Ophthalmologica. 96, 2, p. e156-e163

Research output: Contribution to journalArticle

2017

Corrigendum to "Genotype-Phenotype Characterization of Novel Variants in Six Italian Patients with Familial Exudative Vitreoretinopathy"

Iarossi, G., Bertelli, M., Maltese, P. E., Gusson, E., Marchini, G., Bruson, A., Benedetti, S., Volpetti, S., Catena, G., Buzzonetti, L. & Ziccardi, L., 2017, In : Journal of Ophthalmology. 2017, p. 7969364

Research output: Contribution to journalArticle

Design and validation of a New MLPA-Based assay for the detection of RS1 gene deletions and application in a large family with X-linked juvenile retinoschisis

Nicoletti, A., Ziccardi, L., Maltese, P. E., Benedetti, S., Palumbo, O., Rendina, M., D'Agruma, L., Falsini, B., Wang, X. & Bertelli, M., Feb 1 2017, In : Genetic Testing and Molecular Biomarkers. 21, 2, p. 116-121 6 p.

Research output: Contribution to journalArticle

Design and Validation of a New MLPA-Based Assay for the Detection of RS1 Gene Deletions and Application in a Large Family with X-Linked Juvenile Retinoschisis.

Nicoletti, A., Ziccardi, L., Maltese, PE., Benedetti, S., Palumbo, O., Rendina, M., D'Agruma, L., Falsini, B., Wang, X. & Bertelli, M., Feb 2017, In : Genetic Testing and Molecular Biomarkers. 21, 2, p. 116-121 6 p., doi: 10.1089/gtmb.2016.0257.

Research output: Contribution to journalArticle

Developmental visual deprivation: long term effects on human cone driven retinal function

Esposito Veneruso, P., Ziccardi, L., Magli, G., Parisi, V., Falsini, B. & Magli, A., Dec 1 2017, In : Graefe's Archive for Clinical and Experimental Ophthalmology. 255, 12, p. 2481-2486 6 p.

Research output: Contribution to journalArticle

Early light deprivation effects on human cone-driven retinal function.

Esposito Veneruso, P., Ziccardi, L., Magli, G., Parisi, V., Falsini, B. & Magli, A., Mar 2017, In : Acta Ophthalmologica. 95, 2, p. 133-139 7 p., doi: 10.1111/aos.13191.

Research output: Contribution to journalArticle

Genotype-Phenotype Characterization of Novel Variants in Six Italian Patients with Familial Exudative Vitreoretinopathy

Iarossi, G., Bertelli, M., Maltese, P. E., Gusson, E., Marchini, G., Bruson, A., Benedetti, S., Volpetti, S., Catena, G., Buzzonetti, L. & Ziccardi, L., Jan 1 2017, In : Journal of Ophthalmology. 2017, 3080245.

Research output: Contribution to journalArticle

Genotype-Phenotype Characterization of Novel Variants in Six Italian Patients with Familial Exudative Vitreoretinopathy

Iarossi, G., Bertelli, M., Maltese, P. E., Gusson, E., Marchini, G., Bruson, A., Benedetti, S., Volpetti, S., Catena, G., Buzzonetti, L. & Ziccardi, L., 2017, In : Journal of Ophthalmology. 2017, p. 3080245

Research output: Contribution to journalArticle

Osteoporosis-pseudoglioma syndrome

Maltese, P., Ziccardi, L., Iarossi, G., Gusson, E., D’Agruma, L., Marchini, G., Buzzonetti, L., Nicoletti, A., Benedetti, S. & Bertelli, M., Sep 3 2017, In : Ophthalmic Genetics. 38, 5, p. 473-479 7 p.

Research output: Contribution to journalArticle

Osteoporosis-pseudoglioma syndrome: Report of two cases and a manifesting carrier

Maltese, P., Ziccardi, L., Iarossi, G., Gusson, E., D’Agruma, L., Marchini, G., Buzzonetti, L., Nicoletti, A., Benedetti, S. & Bertelli, M., Sep 3 2017, In : Ophthalmic Genetics. 38, 5, p. 473-479 7 p.

Research output: Contribution to journalArticle

2016

Bilateral symmetry of visual function loss in cone–rod dystrophies

Galli-Resta, L., Falsini, B., Rossi, G., Piccardi, M., Ziccardi, L., Fadda, A., Minnella, A., Marangoni, D., Placidi, G., Campagna, F., Abed, E., Bertelli, M., Zuntini, M. & Resta, G., Jul 1 2016, In : Investigative Ophthalmology and Visual Science. 57, 8, p. 3759-3768 10 p.

Research output: Contribution to journalArticle

Commentary: Citicoline: A food beneficial for patients suffering from or threated with glaucoma

Parisi, V., Ziccardi, L., Roberti, G., Tanga, L. & Manni, G., 2016, In : Frontiers in Aging Neuroscience. 8, AUG, 194.

Research output: Contribution to journalComment/debate

Early light deprivation effects on human cone-driven retinal function

Esposito Veneruso, P., Ziccardi, L., Magli, G., Parisi, V., Falsini, B. & Magli, A., 2016, (Accepted/In press) In : Acta Ophthalmologica.

Research output: Contribution to journalArticle

Investigation of adaptive optics imaging biomarkers for detecting pathological changes of the cone mosaic in patients with type 1 diabetes mellitus

Lombardo, M., Parravano, M., Serrao, S., Ziccardi, L., Giannini, D. & Lombardo, G., Mar 10 2016, In : PLoS One. 11, 3, e0151380.

Research output: Contribution to journalArticle

Ocular and systemic safety of a recombinant AAV8 vector for X-linked retinoschisis gene therapy: GLP studies in rabbits and Rs1-KO mice

Marangoni, D., Bush, R. A., Zeng, Y., Wei, L. L., Ziccardi, L., Vijayasarathy, C., Bartoe, J. T., Palyada, K., Santos, M., Hiriyanna, S., Wu, Z., Colosi, P. & Sieving, P. A., Mar 16 2016, In : Molecular Therapy - Methods and Clinical Development. 5, 16011.

Research output: Contribution to journalArticle

Pigmentary degenerative maculopathy as prominent phenotype in an Italian SPG56/CYP2U1 family

Leonardi, L., Ziccardi, L., Marcotulli, C., Rubegni, A., Longobardi, A., Serrao, M., Storti, E., Pierelli, F., Tessa, A., Parisi, V., Santorelli, F. M. & Carlo, C., Apr 1 2016, In : Journal of Neurology. 263, 4, p. 781-783 3 p.

Research output: Contribution to journalArticle

Pigmentary degenerative maculopathy as prominent phenotype in an Italian SPG56/CYP2U1 family

Leonardi, L., Ziccardi, L., Marcotulli, C., Rubegni, A., Longobardi, A., Serrao, M., Storti, E., Pierelli, F., Tessa, A., Parisi, V., Santorelli, F. M. & Carlo, C., Apr 1 2016, In : Journal of Neurology. 263, 4, p. 781-783 3 p.

Research output: Contribution to journalArticle

2015

Multimodal Approach to Monitoring and Investigating Cone Structure and Function in an Inherited Macular Dystrophy

Ziccardi, L., Giannini, D., Lombardo, G., Serrao, S., Dell'Omo, R., Nicoletti, A., Bertelli, M. & Lombardo, M., Aug 1 2015, In : American Journal of Ophthalmology. 160, 2, p. 301-312.e6

Research output: Contribution to journalArticle

Optical coherence tomography in Alzheimer's disease: A meta-analysis

Coppola, G., Di Renzo, A., Ziccardi, L., Martelli, F., Fadda, A., Manni, G., Barboni, P., Pierelli, F., Sadun, A. A. & Parisi, V., Aug 7 2015, In : PLoS One. 10, 8, e0134750.

Research output: Contribution to journalArticle

Synaptic pathology and therapeutic repair in adult retinoschisis mouse by AAV-RS1 transfer

Ou, J., Vijayasarathy, C., Ziccardi, L., Chen, S., Zeng, Y., Marangoni, D., Pope, J. G., Bush, R. A., Wu, Z., Li, W. & Sieving, P. A., Jul 1 2015, In : Journal of Clinical Investigation. 125, 7, p. 2891-2903 13 p.

Research output: Contribution to journalArticle

Treatment with citicoline eye drops enhances retinal function and neural conduction along the visual pathways in open angle glaucoma

Parisi, V., Centofanti, M., Ziccardi, L., Tanga, L., Michelessi, M., Roberti, G. & Manni, G., Aug 1 2015, In : Graefe's Archive for Clinical and Experimental Ophthalmology. 253, 8, p. 1327-1340 14 p.

Research output: Contribution to journalArticle

2014

Sequential spectral domain optical coherence tomography imaging of an eye after successful removal of subfoveal perfluorcarbon liquid collection

Savastano, M. C., Ziccardi, L., Zinzanella, G., Falsini, B. & Minnella, A. M., 2014, In : Retinal Cases and Brief Reports. 8, 3, p. 215-218 4 p.

Research output: Contribution to journalArticle

Short-term effects of vision trainer rehabilitation in patients affected by anisometropic amblyopia: electrofunctional evaluation

Esposito Veneruso, P., Ziccardi, L., Magli, G., Falsini, B. & Magli, A., Dec 1 2014, In : Documenta Ophthalmologica. 129, 3, p. 177-189 13 p.

Research output: Contribution to journalArticle

2013

Early detection of central visual function decline in cone-rod dystrophy by the use of macular focal cone electroretinogram

Galli-Resta, L., Piccardi, M., Ziccardi, L., Fadda, A., Minnella, A., Marangoni, D., Placidi, G., Resta, G. & Falsini, B., 2013, In : Investigative Ophthalmology and Visual Science. 54, 10, p. 6560-6569 10 p.

Research output: Contribution to journalArticle

X-linked retinoschisis

Sieving, P. A., Ziccardi, L. & Trese, M. T., Aug 13 2013, Pediatric Retina: Second Edition. Wolters Kluwer Health

Research output: Chapter in Book/Report/Conference proceedingChapter

2012

Biology of retinoschisin

Vijayasarathy, C., Ziccardi, L. & Sieving, P. A., 2012, Advances in Experimental Medicine and Biology. Vol. 723. p. 513-518 6 p. (Advances in Experimental Medicine and Biology; vol. 723).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Long-term decline of central cone function in retinitis pigmentosa evaluated by focal electroretinogram

Falsini, B., Galli-Resta, L., Fadda, A., Ziccardi, L., Piccardi, M., Iarossi, G. & Resta, G., Nov 2012, In : Investigative Ophthalmology and Visual Science. 53, 12, p. 7701-7709 9 p.

Research output: Contribution to journalArticle