Research Output per year
Research Output 2016 2019
2019
Olaptesed pegol (NOX-A12) with bendamustine and rituximab: a phase IIa study in patients with relapsed/refractory chronic lymphocytic leukemia
Steurer, M., Montillo, M., Scarfò, L., Mauro, F. R., Andel, J., Wildner, S., Trentin, L., Janssens, A., Burgstaller, S., Frömming, A., Dümmler, T., Riecke, K., Baumann, M., Beyer, D., Vauléon, S., Ghia, P., Foà, R., Caligaris-Cappio, F. & Gobbi, M., Oct 1 2019, In : Haematologica. 104, 10, p. 2053-2060 8 p.Research output: Contribution to journal › Article
Open Access
B-Cell Chronic Lymphocytic Leukemia
Oligoribonucleotides
Chemokine CXCL12
Patient Safety
Life Cycle Stages
2018
A retinoic acid-dependent stroma-leukemia crosstalk promotes chronic lymphocytic leukemia progression
Farinello, D., Wozińska, M., Lenti, E., Genovese, L., Bianchessi, S., Migliori, E., Sacchetti, N., Di Lillo, A., Bertilaccio, MTS., De Lalla, C., Valsecchi, R., Gleave, SB., Lligé, D., Scielzo, C., Mauri, L., Ciampa, MG., Scarfò, L., Bernardi, R., Lazarevic, D., Gonzalez-Farre, B. & 8 others, , 2018, In : Nature Communications. 9, 4, 1787.Research output: Contribution to journal › Article
leukemias
Retinoids
B-Cell Chronic Lymphocytic Leukemia
Crosstalk
Tretinoin
Highly similar genomic landscapes in monoclonal b-cell lymphocytosis and ultra-stable chronic lymphocytic leukemia with low frequency of driver mutations
Agathangelidis, A., Ljungström, V., Scarfò, L., Fazi, C., Gounari, M., Pandzic, T., Sutton, LA., Stamatopoulos, K., Tonon, G., Rosenquist, R. & Ghia, P., 2018, In : Haematologica. 103, 5, p. 865-873 9 p.Research output: Contribution to journal › Article
Lymphocytosis
Mutation Rate
B-Cell Chronic Lymphocytic Leukemia
Mutation
B-Lymphocytes
Monoclonal B-cell lymphocytosis: Does the elderly patient need a specialistic approach?
Angelillo, P., Capasso, A., Ghia, P. & Scarfò, L., 2018, In : European Journal of Internal Medicine. 58, p. 2-6 5 p.Research output: Contribution to journal › Article
Lymphocytosis
B-Lymphocytes
Population
No improvement in long-term survival over time for chronic lymphocytic leukemia patients in stereotyped subsets #1 and #2 treated with chemo(immuno)therapy
Baliakas, P., Mattsson, M., Hadzidimitriou, A., Minga, E., Agathangelidis, A., Sutton, LA., Scarfò, L., Davis, Z., Yan, XJ., Plevova, K., Sandberg, Y., Vojdeman, FJ., Tzenou, T., Chu, CC., Veronese, S., Mansouri, L., Smedby, KE., Giudicelli, V., Nguyen-Khac, F., Panagiotidis, P. & 20 others, , 2018, In : Haematologica. 103, 4, p. e158-e161Research output: Contribution to journal › Article
B-Cell Chronic Lymphocytic Leukemia
Survival
Therapeutics
2017
3
Citations
(Scopus)
Calreticulin as a novel B-cell receptor antigen in chronic lymphocytic leukemia
Ten Hacken, E., Gounari, M., Back, JW., Shimanovskaya, E., Scarfò, L., Kim, E., Burks, J., Ponzoni, M., Ramirez, GA., Wierda, WG., Estrov, Z., Keating, MJ., Ferrajoli, A., Stamatopoulos, K., Ghia, P. & Burger, JA., 2017, In : Haematologica. 102, 10, p. e394-e396Research output: Contribution to journal › Article
Calreticulin
B-Cell Antigen Receptors
B-Cell Chronic Lymphocytic Leukemia
5
Citations
(Scopus)
Chronic lymphocytic leukemia with mutated IGHV4-34 receptors: Shared and distinct immunogenetic features and clinical outcomes
Xochelli, A., Baliakas, P., Kavakiotis, I., Agathangelidis, A., Sutton, LA., Minga, E., Ntoufa, S., Tausch, E., Yan, XJ., Shanafelt, T., Plevova, K., Boudjogra, M., Rossi, D., Davis, Z., Navarro, A., Sandberg, Y., Vojdeman, FJ., Scarfò, L., Stavroyianni, N., Sudarikov, A. & 42 others, , 2017, In : Clinical Cancer Research. 23, 17, p. 5292-5301 10 p.Research output: Contribution to journal › Article
Immunogenetics
B-Cell Chronic Lymphocytic Leukemia
B-Lymphocytes
Immunoglobulin G
Immunoglobulin M
Distinct homotypic B-cell receptor interactions shape the outcome of chronic lymphocytic leukaemia
Minici, C., Gounari, M., Übelhart, R., Scarfò, L., Dühren-von Minden, M., Schneider, D., Tasdogan, A., Alkhatib, A., Agathangelidis, A., Ntoufa, S., Chiorazzi, N., Jumaa, H., Stamatopoulos, K., Ghia, P. & Degano, M., 2017, In : Nature Communications. 8, 11, 15746.Research output: Contribution to journal › Article
leukemias
B-Cell Chronic Lymphocytic Leukemia
Cell Communication
B-Lymphocytes
Cells
15
Citations
(Scopus)
Efficacy and safety of dinaciclib vs ofatumumab in patients with relapsed/refractory chronic lymphocytic leukemia
Ghia, P., Scarfò, L., Perez, S., Pathiraja, K., Derosier, M., Small, K., Sisk, CMC. & Patton, N., 2017, In : Blood. 129, 13, p. 1876-1878 3 p.Research output: Contribution to journal › Article
B-Cell Chronic Lymphocytic Leukemia
Refractory materials
Safety
dinaciclib
ofatumumab
23
Citations
(Scopus)
Invariant NKT cells contribute to chronic lymphocytic leukemia surveillance and prognosis
Gorini, F., Azzimonti, L., Delfanti, G., Scarfò, L., Scielzo, C., Bertilaccio, MT., Ranghetti, P., Gulino, A., Doglioni, C., Di Napoli, A., Capri, M., Franceschi, C., Caligaris-Cappio, F., Ghia, P., Bellone, M., Dellabona, P., Casorati, G. & De Lalla, C., 2017, In : Blood. 129, 26, p. 3440-3451 12 p.Research output: Contribution to journal › Article
Natural Killer T-Cells
T-cells
B-Cell Chronic Lymphocytic Leukemia
Disease Progression
Lymphocytes
17
Citations
(Scopus)
Lenalidomide maintenance in patients with relapsed diffuse large B-cell lymphoma who are not eligible for autologous stem cell transplantation: an open label, single-arm, multicentre phase 2 trial
Ferreri, A. J. M., Sassone, M., Zaja, F., Re, A., Spina, M., Rocco, A. D., Fabbri, A., Stelitano, C., Frezzato, M., Rusconi, C., Zambello, R., Couto, S., Ren, Y., Arcari, A., Bertoldero, G., Nonis, A., Scarfò, L., Calimeri, T., Cecchetti, C., Chiozzotto, M. & 2 others, , Mar 1 2017, In : The Lancet Haematology. 4, 3, p. e137-e146 9 p.Research output: Contribution to journal › Article
Lymphoma, Large B-Cell, Diffuse
Stem Cell Transplantation
Maintenance
Recurrence
lenalidomide
17
Citations
(Scopus)
Lenalidomide maintenance in patients with relapsed diffuse large B-cell lymphoma who are not eligible for autologous stem cell transplantation: an open label, single-arm, multicentre phase 2 trial
Ferreri, A. J. M., Sassone, M., Zaja, F., Re, A., Spina, M., Rocco, A. D., Fabbri, A., Stelitano, C., Frezzato, M., Rusconi, C., Zambello, R., Couto, S., Ren, Y., Arcari, A., Bertoldero, G., Nonis, A., Scarfò, L., Calimeri, T., Cecchetti, C., Chiozzotto, M. & 2 others, , Mar 1 2017, In : The Lancet Haematology. 4, 3, p. e137-e146Research output: Contribution to journal › Article
Lymphoma, Large B-Cell, Diffuse
Stem Cell Transplantation
Maintenance
Recurrence
lenalidomide
17
Citations
(Scopus)
Lenalidomide maintenance in patients with relapsed diffuse large B-cell lymphoma who are not eligible for autologous stem cell transplantation: an open label, single-arm, multicentre phase 2 trial
Ferreri, AJM., Sassone, M., Zaja, F., Re, A., Spina, M., Rocco, AD., Fabbri, A., Stelitano, C., Frezzato, M., Rusconi, C., Zambello, R., Couto, S., Ren, Y., Arcari, A., Bertoldero, G., Nonis, A., Scarfò, L., Calimeri, T., Cecchetti, C., Chiozzotto, M. & 2 others, , 2017, In : The Lancet Haematology. 4, 3, p. e137-e146Research output: Contribution to journal › Article
Lymphoma, Large B-Cell, Diffuse
Stem Cell Transplantation
Maintenance
Recurrence
lenalidomide
Synthetic high-density lipoproteins as targeted monotherapy for chronic lymphocytic leukemia
McMahon, KM., Scielzo, C., Angeloni, NL., Deiss-Yehiely, E., Scarfò, L., Ranghetti, P., Ma, S., Kaplan, J., Barbaglio, F., Gordon, LI., Giles, FJ., Thaxton, CS. & Ghia, P., 2017, In : Oncotarget. 8, 7, p. 11219-11227 9 p.Research output: Contribution to journal › Article
B-Cell Chronic Lymphocytic Leukemia
HDL Lipoproteins
Scavenger Receptors
B-Lymphocytes
Cholesterol
5
Citations
(Scopus)
The inhibitory receptor toll interleukin-1R 8 (TIR8/IL-1R8/SIGIRR) is downregulated in chronic lymphocytic leukemia
Vilia, MG., Fonte, E., Veliz Rodriguez, T., Tocchetti, M., Ranghetti, P., Scarfò, L., Papakonstantinou, N., Ntoufa, S., Stamatopoulos, K., Ghia, P. & Muzio, M., 2017, In : Leukemia and Lymphoma. 58, 10, p. 2419-2425 7 p.Research output: Contribution to journal › Article
B-Cell Chronic Lymphocytic Leukemia
Interleukin-8
Down-Regulation
Inflammation
Azacitidine
Toll-like receptor 9 stimulation can induce IκBζ expression and IgM secretion in chronic lymphocytic leukemia cells
Fonte, E., Vilia, MG., Reverberi, D., Sana, I., Scarfò, L., Ranghetti, P., Orfanelli, U., Cenci, S., Cutrona, G., Ghia, P. & Muzio, M., 2017, In : Haematologica. 102, 11, p. 1901-1912 12 p.Research output: Contribution to journal › Article
Toll-Like Receptor 9
B-Cell Chronic Lymphocytic Leukemia
Immunoglobulin M
Toll-Like Receptors
Ligands
Toll-like receptor 9 stimulation can induce IκBζ expression and IgM secretion in chronic lymphocytic leukemia cells
Fonte, E., Vilia, M. G., Reverberi, D., Sana, I., Scarfò, L., Ranghetti, P., Orfanelli, U., Cenci, S., Cutrona, G., Ghia, P., Ghia, P. & Muzio, M., Oct 27 2017, In : Haematologica. 102, 11, p. 1901-1912 12 p.Research output: Contribution to journal › Article
Toll-Like Receptor 9
B-Cell Chronic Lymphocytic Leukemia
Immunoglobulin M
Toll-Like Receptors
Ligands
2016
19
Citations
(Scopus)
HIF-1α regulates the interaction of chronic lymphocytic leukemia cells with the tumor microenvironment
Valsecchi, R., Coltella, N., Belloni, D., Ponente, M., Ten Hacken, E., Scielzo, C., Scarfò, L., Bertilaccio, M. T. S., Brambilla, P., Lenti, E., Boneschi, F. M., Brendolan, A., Ferrero, E., Ferrarini, M., Ghia, P., Tonon, G., Ponzoni, M., Caligaris-Cappio, F. & Bernardi, R., 2016, In : Blood. 127, 16, p. 1987-1997 11 p.Research output: Contribution to journal › Article
Hypoxia-Inducible Factor 1
Tumor Microenvironment
B-Cell Chronic Lymphocytic Leukemia
Tumors
Transcription Factors
Inhibition of chronic lymphocytic leukemia progression by full-length chromogranin A and its N-terminal fragment in mouse models
Bianco, M., Gasparri, A., Generoso, L., Assi, E., Colombo, B., Scarfo, L., Bertilaccio, M. T., Scielzo, C., Ranghetti, P., Dondossola, E., Ponzoni, M., Caligaris-Cappio, F., Ghia, P. & Corti, A., 2016, In : Oncotarget. 7, 27, p. 41725-41736 12 p.Research output: Contribution to journal › Article
Chromogranin A
B-Cell Chronic Lymphocytic Leukemia
Bone Marrow
Heterografts
Dromaiidae
39
Citations
(Scopus)
Targeting Macrophages Sensitizes Chronic Lymphocytic Leukemia to Apoptosis and Inhibits Disease Progression
Galletti, G., Scielzo, C., Barbaglio, F., Rodriguez, T. V., Riba, M., Lazarevic, D., Cittaro, D., Simonetti, G., Ranghetti, P., Scarfò, L., Ponzoni, M., Rocchi, M., Corti, A., Anselmo, A., van Rooijen, N., Klein, C., Ries, C. H., Ghia, P., De Palma, M., Caligaris-Cappio, F. & 1 others, , Feb 23 2016, In : Cell Reports. 14, 7, p. 1748-1760 13 p.Research output: Contribution to journal › Article
Macrophages
B-Cell Chronic Lymphocytic Leukemia
Disease Progression
Apoptosis
Monocytes
What does it mean i have a monoclonal B-cell lymphocytosis?: Recent insights and new challenges
Scarfò, L. & Ghia, P., Apr 1 2016, In : Seminars in Oncology. 43, 2, p. 201 - 208 8 p.Research output: Contribution to journal › Article
Lymphocytosis
B-Lymphocytes