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Research Output

  • 94 Article
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Article
2020

Plasma miRNA-based signatures in CRC screening programs

Zanutto, S., Ciniselli, C. M., Belfiore, A., Lecchi, M., Masci, E., Delconte, G., Primignani, M., Tosetti, G., Dal Fante, M., Fazzini, L., Airoldi, A., Vangeli, M., Turpini, F., Rubis Passoni, G. G., Viaggi, P., Arena, M., Motta, R. I. O., Cantù, A. M., Crosta, C., De Roberto, G. & 10 others, Iannuzzi, F., Cassinotti, A., Dall'Olio, V., Tizzoni, L., Sozzi, G., Meroni, E., Bisanti, L., Pierotti, M. A., Verderio, P. & Gariboldi, M., 2020, In : International Journal of Cancer. 146, 4, p. 1164-1173

Research output: Contribution to journalArticle

2019
Open Access
2017

A methodological procedure for evaluating the impact of hemolysis on circulating microRNAs

Pizzamiglio, S., Zanutto, S., Ciniselli, C. M., Belfiore, A., Bottelli, S., Gariboldi, M. & Verderio, P., Jan 1 2017, In : Oncology Letters. 13, 1, p. 315-320 6 p.

Research output: Contribution to journalArticle

Metformin transiently inhibits colorectal cancer cell proliferation as a result of either AMPK activation or increased ROS production

Mogavero, A., Maiorana, M. V., Zanutto, S., Varinelli, L., Bozzi, F., Belfiore, A., Volpi, C. C., Gloghini, A., Pierotti, M. A. & Gariboldi, M., 2017, In : Scientific Reports. 7, 1

Research output: Contribution to journalArticle

MIF/CD74 axis is a target for novel therapies in colon carcinomatosis

Bozzi, F., Mogavero, A., Varinelli, L., Belfiore, A., Manenti, G., Caccia, C., Volpi, C. C., Beznoussenko, G. V., Milione, M., Leoni, V., Gloghini, A., Mironov, A. A., Leo, E., Pilotti, S., Pierotti, M. A., Bongarzone, I. & Gariboldi, M., Jan 23 2017, In : Journal of Experimental and Clinical Cancer Research. 36, 1, p. 1-15 15 p.

Research output: Contribution to journalArticle

MIF/CD74 axis is a target for novel therapies in colon carcinomatosis.

Bozzi, F., Mogavero, A., Varinelli, L., Belfiore, A., Manenti, G., Caccia, C., Volpi, C. C., Beznoussenko, G. V., Milione, M., Leoni, V., Gloghini, A., Mironov, A. A., Leo, E., Pilotti, S., Alessandro Pierotti, M., Bongarzone, I. & Gariboldi, M., Jan 1 2017, In : Journal of Experimental and Clinical Cancer Research. 36, 1, p. 16 1 p.

Research output: Contribution to journalArticle

Integration of genome scale data for identifying new players in colorectal cancer

Sokolova, V., Crippa, E. & Gariboldi, M., Jan 14 2016, In : World Journal of Gastroenterology. 22, 2, p. 534-545 12 p.

Research output: Contribution to journalArticle

miR-342 overexpression results in a synthetic lethal phenotype in BRCA1-mutant HCC1937 breast cancer cells

Crippa, E., Folini, M., Pennati, M., Zaffaroni, N., Pierotti, M. A. & Gariboldi, M., 2016, In : Oncotarget. 7, 14, p. 18594-18604 11 p.

Research output: Contribution to journalArticle

2015

DPD and UGT1A1 deficiency in colorectal cancer patients receiving triplet chemotherapy with fluoropyrimidines, oxaliplatin and irinotecan

Falvella, F. S., Cheli, S., Martinetti, A., Mazzali, C., Iacovelli, R., Maggi, C., Gariboldi, M., Pierotti, M. A., Di Bartolomeo, M., Sottotetti, E., Mennitto, R., Bossi, I., De Braud, F., Clementi, E. & Pietrantonio, F., Sep 1 2015, In : British Journal of Clinical Pharmacology. 80, 3, p. 581-588 8 p.

Research output: Contribution to journalArticle

Moving from discovery to validation in circulating microRNA research

Verderio, P., Bottelli, S., Ciniselli, C. M., Pierotti, M. A., Zanutto, S., Gariboldi, M. & Pizzamiglio, S., Apr 1 2015, In : International Journal of Biological Markers. 30, 2, p. e258-e261

Research output: Contribution to journalArticle

The Effects of miR-20a on p21: Two Mechanisms Blocking Growth Arrest in TGF-β-Responsive Colon Carcinoma

Sokolova, V., Fiorino, A., Zoni, E., Crippa, E., Reid, J. F., Gariboldi, M. & Pierotti, M. A., Dec 1 2015, In : Journal of Cellular Physiology. 230, 12, p. 3105-3114 10 p.

Research output: Contribution to journalArticle

2014

Activity of temozolomide in patients with advanced chemorefractory colorectal cancer and MGMT promoter methylation

Pietrantonio, F., Perrone, F., De Braud, F., Castano, A., Maggi, C., Bossi, I., Gevorgyan, A., Biondani, P., Pacifici, M., Busico, A., Gariboldi, M., Festinese, F., Tamborini, E. & Di Bartolomeo, M., 2014, In : Annals of Oncology. 25, 2, p. 404-408 5 p., mdt547.

Research output: Contribution to journalArticle

A normalization strategy for the analysis of plasma microRNA qPCR data in colorectal cancer

Pizzamiglio, S., Bottelli, S., Ciniselli, C. M., Zanutto, S., Bertan, C., Gariboldi, M., Pierotti, M. A. & Verderio, P., Apr 15 2014, In : International Journal of Cancer. 134, 8, p. 2016-2018 3 p.

Research output: Contribution to journalArticle

Circulating free DNA in a screening program for early colorectal cancer detection

Perrone, F., Lampis, A., Bertan, C., Verderio, P., Ciniselli, C. M., Pizzamiglio, S., Frattini, M., Nucifora, M., Molinari, F., Gallino, G., Gariboldi, M., Meroni, E., Leo, E., Pierotti, M. A. & Pilotti, S., 2014, In : Tumori. 100, 2, p. 115-121 7 p.

Research output: Contribution to journalArticle

Circulating miR-378 in plasma: A reliable, haemolysis-independent biomarker for colorectal cancer

Zanutto, S., Pizzamiglio, S., Ghilotti, M., Bertan, C., Ravagnani, F., Perrone, F., Leo, E., Pilotti, S., Verderio, P., Gariboldi, M. & Pierotti, M. A., Feb 18 2014, In : British Journal of Cancer. 110, 4, p. 1001-1007 7 p.

Research output: Contribution to journalArticle

Combined analysis of chromosomal instabilities and gene expression for colon cancer progression inference

Cava, C., Zoppis, I., Gariboldi, M., Castiglioni, I., Mauri, G. & Antoniotti, M., Jan 24 2014, In : Journal of Clinical Bioinformatics. 4, 1, 2.

Research output: Contribution to journalArticle

miR-342 Regulates BRCA1 expression through modulation of ID4 in breast cancer

Crippa, E., Lusa, L., De Cecco, L., Marchesi, E., Calin, G. A., Radice, P., Manoukian, S., Peissel, B., Daidone, M. G., Gariboldi, M. & Pierotti, M. A., Jan 27 2014, In : PLoS One. 9, 1, e87039.

Research output: Contribution to journalArticle

NqA: An R-based algorithm for the normalization and analysis of microRNA quantitative real-time polymerase chain reaction data

Verderio, P., Bottelli, S., Ciniselli, C. M., Pierotti, M. A., Gariboldi, M. & Pizzamiglio, S., Sep 15 2014, In : Analytical Biochemistry. 461, p. 7-9 3 p.

Research output: Contribution to journalArticle

2013

A review on biomarkers for prediction of treatment outcome in gastric cancer

Pietrantonio, F., De Braud, F., Da Prat, V., Perrone, F., Pierotti, M. A., Gariboldi, M., Fanetti, G., Biondani, P., Pellegrinelli, A., Bossi, I. & Di Bartolomeo, M., Apr 2013, In : Anticancer Research. 33, 4, p. 1257-1266 10 p.

Research output: Contribution to journalArticle

Correction: Effects of warm ischemic time on gene expression profiling in colorectal cancer tissues and normal mucosa (PLoS ONE)

Musella, V., Verderio, P., Reid, J. F., Pizzamiglio, S., Gariboldi, M., Callari, M., Milione, M., De Cecco, L., Veneroni, S., Pierotti, M. A. & Daidone, M. G., Jun 7 2013, In : PLoS One. 8, 6

Research output: Contribution to journalArticle

Effects of Warm Ischemic Time on Gene Expression Profiling in Colorectal Cancer Tissues and Normal Mucosa

Musella, V., Verderio, P., Reid, J. F., Pizzamiglio, S., Gariboldi, M., Callari, M., Massimo, M., De Cecco, L., Veneroni, S., Pierotti, M. A. & Daidone, M. G., Jan 15 2013, In : PLoS One. 8, 1, e53406.

Research output: Contribution to journalArticle

Gold-nanoparticle-based colorimetric discrimination of cancer-related point mutations with picomolar sensitivity

Valentini, P., Fiammengo, R., Sabella, S., Gariboldi, M., Maiorano, G., Cingolani, R. & Pompa, P. P., Jun 25 2013, In : ACS Nano. 7, 6, p. 5530-5538 9 p.

Research output: Contribution to journalArticle

Role of cMET in the development and progression of colorectal cancer

Pérez-Vargas, J. C. S., Biondani, P., Maggi, C., Gariboldi, M., Gloghini, A., Inno, A., Volpi, C. C., Gualeni, A. V., di Bartolomeo, M., de Braud, F., Castano, A., Bossi, I. & Pietrantonio, F., Sep 3 2013, In : International Journal of Molecular Sciences. 14, 9, p. 18056-18077 22 p.

Research output: Contribution to journalArticle

Targeting metabolism for cancer treatment and prevention: Metformin, an old drug with multi-faceted effects

Pierotti, M. A., Berrino, F., Gariboldi, M., Melani, C., Mogavero, A., Negri, T., Pasanisi, P. & Pilotti, S., Mar 21 2013, In : Oncogene. 32, 12, p. 1475-1487 13 p.

Research output: Contribution to journalArticle

2012

Methylation status in patients with early stage colon cancer: A new prognostic marker?

Zanutto, S., Pizzamiglio, S., Lampis, A., Camerini, T., Di Mauro, M. G., Pierotti, M. A., Verderio, P. & Gariboldi, M., Jan 15 2012, In : International Journal of Cancer. 130, 2, p. 488-489 2 p.

Research output: Contribution to journalArticle

miRNA profiling in colorectal cancer highlights miR-1 involvement in MET-dependent proliferation

Reid, J. F., Sokolova, V., Zoni, E., Lampis, A., Pizzamiglio, S., Bertan, C., Zanutto, S., Perrone, F., Camerini, T., Gallino, G., Verderio, P., Leo, E., Pilotti, S., Gariboldi, M. & Pierotti, M. A., Apr 2012, In : Molecular Cancer Research. 10, 4, p. 504-515 12 p.

Research output: Contribution to journalArticle

2011

ERG deregulation induces PIM1 over-expression and aneuploidy in prostate epithelial cells

Magistroni, V., Mologni, L., Sanselicio, S., Reid, J. F., Redaelli, S., Piazza, R., Viltadi, M., Bovo, G., Strada, G., Grasso, M., Gariboldi, M. & Gambacorti-Passerini, C., Nov 30 2011, In : PLoS One. 6, 11, e28162.

Research output: Contribution to journalArticle

Gene expression analysis reveals a different transcriptomic landscape in female and male breast cancer

Callari, M., Cappelletti, V., De Cecco, L., Musella, V., Miodini, P., Veneroni, S., Gariboldi, M., Pierotti, M. A. & Daidone, M. G., Jun 2011, In : Breast Cancer Research and Treatment. 127, 3, p. 601-610 10 p.

Research output: Contribution to journalArticle

Transcriptional characteristics of familial non-BRCA1/BRCA2 breast tumors

Fernández-Ramires, R., Gõmez, G., Muñoz-Repeto, I., De Cecco, L., Llort, G., Cazorla, A., Blanco, I., Gariboldi, M., Pierotti, M. A., Benítez, J. & Osorio, A., Jun 1 2011, In : International Journal of Cancer. 128, 11, p. 2635-2644 10 p.

Research output: Contribution to journalArticle

2010

Chromosome band 17q21 in breast cancer: Significant association between beclin 1 loss and HER2/NEU amplification

Negri, T., Tarantino, E., Orsenigo, M., Reid, J. F., Gariboldi, M., Zambetti, M., Pierotti, M. A. & Pilotti, S., Oct 2010, In : Genes Chromosomes and Cancer. 49, 10, p. 901-909 9 p.

Research output: Contribution to journalArticle

Molecularly targeted therapies for colorectal cancer: Strategies for implementing translational research in clinical trials

Zwierzina, H., Bardelli, A., Ciardiello, F., Gariboldi, M., Håkansson, L., Lambrechts, D., Lind, G. E., Loeffler-Ragg, J., Schmoll, H., Siena, S., Tabernero, J. & Van Cutsem, E., Dec 2010, In : Current Opinion in Molecular Therapeutics. 12, 6, p. 703-711 9 p.

Research output: Contribution to journalArticle

Molecular markers for prediction of risk of radiation-related injury to normal tissue

Ghilotti, M., Pierotti, M. A. & Gariboldi, M., 2010, In : Journal of Nucleic Acids Investigation. 1, 1, p. 55-61 7 p.

Research output: Contribution to journalArticle

2009

Gene expression profiling integrated into network modelling reveals heterogeneity in the mechanisms of BRCA1 tumorigenesis

Fernández-Ramires, R., Solé, X., De Cecco, L., Llort, G., Cazorla, A., Bonifaci, N., Garcia, M. J., Caldés, T., Blanco, I., Gariboldi, M., Pierotti, M. A., Pujana, M. A., Benítez, J. & Osorio, A., Oct 20 2009, In : British Journal of Cancer. 101, 8, p. 1469-1480 12 p.

Research output: Contribution to journalArticle

Integrative approach for prioritizing cancer genes in sporadic colon cancer

Reid, J. F., Gariboldi, M., Sokolova, V., Capobianco, P., Lampis, A., Perrone, F., Signoroni, S., Costa, A., Leo, E., Pilotti, S. & Pierotti, M. A., Nov 2009, In : Genes Chromosomes and Cancer. 48, 11, p. 953-962 10 p.

Research output: Contribution to journalArticle

Misbehaviour of XIST RNA in breast cancer cells

Sirchia, S. M., Tabano, S., Monti, L., Recalcati, M. P., Gariboldi, M., Grati, F. R., Porta, G., Finelli, P., Radice, P. & Miozzo, M., May 15 2009, In : PLoS One. 4, 5, e5559.

Research output: Contribution to journalArticle

2008

Metallothionein 1G acts as an oncosupressor in papillary thyroid carcinoma

Ferrario, C., Lavagni, P., Gariboldi, M., Miranda, C., Losa, M., Cleris, L., Formelli, F., Pilotti, S., Pierotti, M. A. & Greco, A., May 2008, In : Laboratory Investigation. 88, 5, p. 474-481 8 p.

Research output: Contribution to journalArticle

Patterns and changes in gene expression following neo-adjuvant anti-estrogen treatment in estrogen receptor-positive breast cancer

Cappelletti, V., Gariboldi, M., De Cecco, L., Toffanin, S., Reid, J. F., Lusa, L., Bajetta, E., Celio, L., Greco, M., Fabbri, A., Pierotti, M. A. & Daidone, M. G., Jun 2008, In : Endocrine-Related Cancer. 15, 2, p. 439-449 11 p.

Research output: Contribution to journalArticle

Re: Molecular basis for estrogen receptor α deficiency in BRCA1-linked breast cancer

Lusa, L., Peissel, B., Manoukian, S., Marchesi, E., Radice, P., Pierotti, M. A. & Gariboldi, M., May 2008, In : Journal of the National Cancer Institute. 100, 10, p. 752-753 2 p.

Research output: Contribution to journalArticle

2007

Analysis of gene expression identifies PLAB as a mediator of the apoptotic activity of fenretinide in human ovarian cancer cells

Appierto, V., Villani, M. G., Cavadini, E., Gariboldi, M., De Cecco, L., Pierotti, M. A., Lambert, J. R., Reid, J., Tiberio, P., Colombo, N. & Formelli, F., Jun 7 2007, In : Oncogene. 26, 27, p. 3952-3962 11 p.

Research output: Contribution to journalArticle

Challenges in projecting clustering results across gene expression-profiling datasets

Lusa, L., McShane, L. M., Reid, J. F., De Cecco, L., Ambrogi, F., Biganzoli, E., Gariboldi, M. & Pierotti, M. A., Nov 2007, In : Journal of the National Cancer Institute. 99, 22, p. 1715-1723 9 p.

Research output: Contribution to journalArticle

2006

M-cam expression as marker of poor prognosis in epithelial ovarian cancer

Aldovini, D., Demichelis, F., Doglioni, C., Di Vizio, D., Galligioni, E., Brugnara, S., Zeni, B., Griso, C., Pegoraro, C., Zannoni, M., Gariboldi, M., Balladore, E., Mezzanzanica, D., Canevari, S. & Barbareschi, M., Oct 15 2006, In : International Journal of Cancer. 119, 8, p. 1920-1926 7 p.

Research output: Contribution to journalArticle

Molecular predictors of response and outcome in ovarian cancer

Canevari, S., Gariboldi, M., Reid, J. F., Bongarzone, I. & Pierotti, M. A., Oct 2006, In : Critical Reviews in Oncology/Hematology. 60, 1, p. 19-37 19 p.

Research output: Contribution to journalArticle

Questioning the utility of pooling samples in microarray experiments with cell lines

Lusa, L., Cappelletti, V., Gariboldi, M., Ferrario, C., De Cecco, L., Reid, J. F., Toffanin, S., Gallus, G., McShane, L. M., Daidone, M. G. & Pierotti, M. A., Apr 2006, In : International Journal of Biological Markers. 21, 2, p. 67-73 7 p.

Research output: Contribution to journalArticle

Regulation of lipocalin-2 gene by the cancer chemopreventive retinoid 4-HPR

Caramuta, S., De Cecco, L., Reid, J. F., Zannini, L., Gariboldi, M., Kjeldsen, L., Pierotti, M. A. & Delia, D., Oct 1 2006, In : International Journal of Cancer. 119, 7, p. 1599-1606 8 p.

Research output: Contribution to journalArticle

Transcriptional network dynamics in macrophage activation

Nilsson, R., Bajic, V. B., Suzuki, H., di Bernardo, D., Björkegren, J., Katayama, S., Reid, J. F., Sweet, M. J., Gariboldi, M., Carninci, P., Hayashizaki, Y., Hume, D. A., Tegner, J. & Ravasi, T., Aug 2006, In : Genomics. 88, 2, p. 133-142 10 p.

Research output: Contribution to journalArticle

2005

Gene expression profile identifies a rare epithelioid variant case of pleomorphic liposarcoma carrying FUS-CHOP transcript

De Cecco, L., Gariboldi, M., Reid, J. F., Lagonigro, M. S., Tamborini, E., Albertini, V., Staurengo, S., Pilotti, S. & Pierotti, M. A., Mar 2005, In : Histopathology. 46, 3, p. 334-341 8 p.

Research output: Contribution to journalArticle