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Research Output 1993 2019

2019

Endo-therapies for biliary duct-to-duct anastomotic stricture after liver transplantation: Outcomes of a nationwide survey

Cantù, P., Tarantino, I., Baldan, A., Mutignani, M., Tringali, A., Lombardi, G., Cerofolini, A., Di Sario, A., Catalano, G., Bertani, H., Ghinolfi, D., Boarino, V., Masci, E., Bulajic, M., Pisani, A., Fantin, A., Ligresti, D., Barresi, L., Traina, M., Ravelli, P. & 26 others, Forti, E., Barbaro, F., Costamagna, G., Rodella, L., Maroni, L., Salizzoni, M., Conigliaro, R., Filipponi, F., Merighi, A., Staiano, T., Monteleone, M., Mazzaferro, V., Zucchi, E., Zilli, M., Nadal, E., Rosa, R., Santi, G., Parzanese, I., De Carlis, L., Donato, M. F., Lampertico, P., Maggi, U., Caccamo, L., Rossi, G., Vecchi, M. & Penagini, R., 2019, In : Liver International. 39, 7, p. 1355-1362 8 p.

Research output: Contribution to journalArticle

The PROSit cohort of infliximab biosimilar in IBD: A prolonged follow-up on the effectiveness and safety across Italy

Armuzzi, A., Fiorino, G., Variola, A., Manetti, N., Fries, W., Orlando, A., Maconi, G., Bossa, F., Cappello, M., Biancone, L., Cantoro, L., Costa, F., D'Incà, R., Lionetti, P., Principi, M., Castiglione, F., Annunziata, M. L., Di Sabatino, A., Di Girolamo, M., Terpin, M. M. & 43 others, Cortelezzi, C. C., Saibeni, S., Amato, A., Ardizzone, S., Guidi, L., Danese, S., Massella, A., Ventra, A., Rizzuto, G., Massari, A., Perri, F., Annese, V., Saettone, S., Tari, R., Petruzzellis, C., Meucci, G., Imperiali, G., Guglielmi, F. W., Mazzuoli, S., Caserta, L., Parodi, M. C., Colli, A., Ronchetti, A., Pugliese, D., Geccherle, A., Rogai, F., Milani, S., Renna, S., Cassinotti, A., Andriulli, A., Martino, G., Scrivo, B., Troncone, E., Kohn, A., Bertani, L., Lorenzon, G., Ghione, S., Nardone, O., Vecchi, M., Bertani, A., Bosani, M. A., Bezzio, C. & Salerno, R., 2019, In : Inflammatory Bowel Diseases. 25, 3, p. 568-579 12 p.

Research output: Contribution to journalArticle

The PROSit cohort of infliximab biosimilar in IBD: A prolonged follow-up on the effectiveness and safety across Italy

Armuzzi, A., Fiorino, G., Variola, A., Manetti, N., Fries, W., Orlando, A., Maconi, G., Bossa, F., Cappello, M., Biancone, L., Cantoro, L., Costa, F., D'Incà, R., Lionetti, P., Principi, M., Castiglione, F., Annunziata, M. L., Di Sabatino, A., Di Girolamo, M., Terpin, M. M. & 43 others, Cortelezzi, C. C., Saibeni, S., Amato, A., Ardizzone, S., Guidi, L., Danese, S., Massella, A., Ventra, A., Rizzuto, G., Massari, A., Perri, F., Annese, V., Saettone, S., Tari, R., Petruzzellis, C., Meucci, G., Imperiali, G., Guglielmi, F. W., Mazzuoli, S., Caserta, L., Parodi, M. C., Colli, A., Ronchetti, A., Pugliese, D., Geccherle, A., Rogai, F., Milani, S., Renna, S., Cassinotti, A., Andriulli, A., Martino, G., Scrivo, B., Troncone, E., Kohn, A., Bertani, L., Lorenzon, G., Ghione, S., Nardone, O., Vecchi, M., Bertani, A., Bosani, M. A., Bezzio, C. & Salerno, R., 2019, In : Inflammatory Bowel Diseases. 25, 3, p. 568-579 12 p.

Research output: Contribution to journalArticle

Biosimilar Pharmaceuticals
Inflammatory Bowel Diseases
Italy
Safety
Crohn Disease
2018

HOXB7 overexpression in lung cancer is a hallmark of acquired stem-like phenotype

Monterisi, S., Lo Riso, P., Russo, K., Bertalot, G., Vecchi, M., Testa, G., DI Fiore, P. P. & Bianchi, F., Jun 1 2018, In : Oncogene. 37, 26, p. 3575-3588 14 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Lung Neoplasms
Phenotype
Stem Cells
Body Patterning
MicroRNAs
Needles
Lung Neoplasms
Cell Line
Mediastinoscopy
Inflammatory Bowel Diseases
Referral and Consultation
Consensus
Rheumatology
Gastroenterology
2017
Lung Neoplasms
Genes
Confidence Intervals
Atlases
Adenocarcinoma of lung

The PROSIT-BIO Cohort: A Prospective Observational Study of Patients with Inflammatory Bowel Disease Treated with Infliximab Biosimilar

Fiorino, G., Manetti, N., Armuzzi, A., Orlando, A., Variola, A., Bonovas, S., Bossa, F., Maconi, G., D'Incà, R., Lionetti, P., Cantoro, L., Fries, W., Annunziata, M. L., Costa, F., Terpin, M. M., Biancone, L., Cortelezzi, C. C., Amato, A., Ardizzone, S., Danese, S. & 43 others, Guidi, L., Rizzuto, G., Massella, A., Andriulli, A., Massari, A., Lorenzon, G., Ghione, S., Kohn, A., Ventra, A., Annese, V., Principi, M., Di Girolamo, M., Bertani, A., Saettone, S., Tari, R., Petruzzellis, C., Guglielmi, F. W., Mazzuoli, S., Cappello, M., Viola, A., Castiglione, F., Nardone, O., Di Sabatino, A., Saibeni, S., Bezzio, C., Caserta, L., Parodi, M. C., Meucci, G., Colli, A., Ronchetti, A., Vecchi, M., Bertani, L., Bosani, M. A., Tronconi, E., Imperiali, G., Salerno, R., Rogai, F., Milani, S., Pugliese, D., Renna, S., Geccherle, A., Martino, G. & Cassinotti, A., 2017, In : Inflammatory Bowel Diseases. 23, 2, p. 233-243 11 p.

Research output: Contribution to journalArticle

The pseudophosphatase STYX targets the F-box of FBXW7 and inhibits SCFFBXW7 function

Reiterer, V., Figueras-Puig, C., Le Guerroue, F., Confalonieri, S., Vecchi, M., Jalapothu, D., Kanse, S. M., Deshaies, R. J., Di Fiore, P. P., Behrends, C. & Farhan, H., Feb 1 2017, In : EMBO Journal. 36, 3, p. 260-273 14 p.

Research output: Contribution to journalArticle

F-Box Proteins
SKP Cullin F-Box Protein Ligases
Tumor Suppressor Proteins
Proteins
Cell proliferation
2016

RAB2A controls MT1-MMP endocytic and E-cadherin polarized Golgi trafficking to promote invasive breast cancer programs

Kajiho, H., Kajiho, Y., Frittoli, E., Confalonieri, S., Bertalot, G., Viale, G., Di Fiore, P. P., Oldani, A., Garre, M., Beznoussenko, G. V., Palamidessi, A., Vecchi, M., Chavrier, P., Perez, F. & Scita, G., Jul 1 2016, In : EMBO Reports. 17, 7, p. 1061-1080 20 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 14
Cadherins
Tumors
Cells
Breast Neoplasms
Non-Small Cell Lung Carcinoma
Lung Neoplasms
RNA
anaplastic lymphoma kinase
Calibration

The pseudophosphatase STYX targets the F-box of FBXW7 and inhibits SCFFBXW7 function

Reiterer, V., Figueras-Puig, C., Le Guerroue, F., Confalonieri, S., Vecchi, M., Jalapothu, D., Kanse, S. M., Deshaies, R. J., Di Fiore, P. P., Behrends, C. & Farhan, H., 2016, (Accepted/In press) In : EMBO Journal.

Research output: Contribution to journalArticle

F-Box Proteins
SKP Cullin F-Box Protein Ligases
Tumor Suppressor Proteins
Proteins
Cell proliferation
2015
Neoplasm Genes
MicroRNAs
Databases
Gene Expression
Breast Neoplasms
2014

Memo is a copper-dependent redox protein with an essential role in migration and metastasis

MacDonald, G., Nalvarte, I., Smirnova, T., Vecchi, M., Aceto, N., Dolemeyer, A., Frei, A., Lienhard, S., Wyckoff, J., Hess, D., Seebacher, J., Keusch, J. J., Gut, H., Salaun, D., Mazzarol, G., Disalvatore, D., Bentires-Alj, M., Di Fiore, P. P., Badache, A. & Hynes, N. E., Jun 10 2014, In : Science Signaling. 7, 329, ra56.

Research output: Contribution to journalArticle

Oxidation-Reduction
Copper
Cells
Breast Neoplasms
Neoplasm Metastasis

Memo is a copper-dependent redox protein with an essential role in migration and metastasis (Science Signaling 7, 329 (ra56))

MacDonald, G., Nalvarte, I., Smirnova, T., Vecchi, M., Aceto, N., Dolemeyer, A., Frei, A., Lienhard, S., Wyckoff, J., Hess, D., Seebacher, J., Keusch, J. J., Gut, H., Salaun, D., Mazzarol, G., Disalvatore, D., Bentires-Alj, M., Di Fiore, P. P., Badache, A. & Hynes, N. E., Jul 8 2014, In : Science Signaling. 333, er4.

Research output: Contribution to journalArticle

The evolving field of PCR: Which method will you choose?

Meani, N. & Vecchi, M., 2014, In : European Pharmaceutical Review. 19, 6, p. 12-16 5 p.

Research output: Contribution to journalArticle

Polymerase chain reaction
Molecular Biology
Forensic Genetics
Polymerase Chain Reaction
Genetic Research

The Fragile X Protein binds mRNAs involved in cancer progression and modulates metastasis formation [EMBO Mol Med, 5, (2013) 1523-1536, DOI: 10.1002/emmm.201302847]

Lucá, R., Averna, M., Zalfa, F., Vecchi, M., Bianchi, F., La Fata, G., Del Nonno, F., Nardacci, R., Bianchi, M., Nuciforo, P., Munck, S., Parrella, P., Moura, R., Signori, E., Alston, R., Kuchnio, A., Giulia Farace, M., Michele Fazio, V., Piacentini, M., De Strooper, B. & 7 others, Achsel, T., Neri, G., Neven, P., Evans, D. G., Carmeliet, P., Mazzone, M. & Bagni, C., 2014, In : EMBO Molecular Medicine. 6, 4, p. 567-568 2 p.

Research output: Contribution to journalArticle

2013

The Fragile X Protein binds mRNAs involved in cancer progression and modulates metastasis formation

Lucá, R., Averna, M., Zalfa, F., Vecchi, M., Bianchi, F., Fata, G. L., Del Nonno, F., Nardacci, R., Bianchi, M., Nuciforo, P., Munck, S., Parrella, P., Moura, R., Signori, E., Alston, R., Kuchnio, A., Farace, M. G., Fazio, V. M., Piacentini, M., De Strooper, B. & 7 others, Achsel, T., Neri, G., Neven, P., Evans, D. G., Carmeliet, P., Mazzone, M. & Bagni, C., Oct 2013, In : EMBO Molecular Medicine. 5, 10, p. 1523-1536 14 p.

Research output: Contribution to journalArticle

Fragile X Mental Retardation Protein
Neoplasm Metastasis
Messenger RNA
Fragile X Syndrome
Neoplasms
2010
Neoplastic Stem Cells
Stem cells
Breast Neoplasms
Tumors
Cells

Copine-III interacts with ErbB2 and promotes tumor cell migration

Heinrich, C., Keller, C., Boulay, A., Vecchi, M., Bianchi, M., Sack, R., Lienhard, S., Duss, S., Hofsteenge, J. & Hynes, N. E., Mar 2010, In : Oncogene. 29, 11, p. 1598-1610 13 p.

Research output: Contribution to journalArticle

Cell Movement
Neoplasms
Breast Neoplasms
Tissue Array Analysis
Isotope Labeling
Gastric Parietal Cells
Stomach
Clathrin
epsin
Proton-Translocating ATPases
2008

Breast cancer metastases are molecularly distinct from their primary tumors

Vecchi, M., Confalonieri, S., Nuciforo, P., Viganò, M. A., Capra, M., Bianchi, M., Nicosia, D., Bianchi, F., Galimberti, V., Viale, G., Palermo, G., Riccardi, A., Campanini, R., Daidone, M. G., Pierotti, M. A., Pece, S. & Di Fiore, P. P., Apr 3 2008, In : Oncogene. 27, 15, p. 2148-2158 11 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Neoplasm Metastasis
Neoplasms
Genes
Lymph Nodes
2007

Gene expression analysis of early and advanced gastric cancers

Vecchi, M., Nuciforo, P., Romagnoli, S., Confalonieri, S., Pellegrini, C., Serio, G., Quarto, M., Capra, M., Roviaro, G. C., Contessini Avesani, E., Corsi, C., Coggi, G., Di Fiore, P. P. & Bosari, S., Jun 21 2007, In : Oncogene. 26, 29, p. 4284-4294 11 p.

Research output: Contribution to journalArticle

Stomach Neoplasms
Gene Expression
Neoplasms
In Situ Hybridization
Stomach

Survival prediction of stage I lung adenocarcinomas by expression of 10 genes

Bianchi, F., Nuciforo, P., Vecchi, M., Bernard, L., Tizzoni, L., Marchetti, A., Buttitta, F., Felicioni, L., Nicassio, F. & Di Fiore, P. P., Nov 1 2007, In : Journal of Clinical Investigation. 117, 11, p. 3436-3444 9 p.

Research output: Contribution to journalArticle

Gene Expression
Survival
Lung Neoplasms
Polymerase Chain Reaction
Genes
2005

A cancer-specific transcriptional signature in human neoplasia

Nicassio, F., Bianchi, F., Capra, M., Vecchi, M., Confalonieri, S., Bianchi, M., Pajalunga, D., Crescenzi, M., Bonapace, I. M. & Di Fiore, P. P., Nov 2005, In : Journal of Clinical Investigation. 115, 11, p. 3015-3025 11 p.

Research output: Contribution to journalArticle

Neoplasms
Tumor Cell Line
Genes
Retinoblastoma Protein
Neoplasm Genes

It's HIP to be a hub: New trends for old-fashioned proteins

Vecchi, M. & Di Fiore, P. P., Jul 2005, In : Journal of Cell Biology. 170, 2, p. 169-171 3 p.

Research output: Contribution to journalArticle

Cytoplasmic and Nuclear Receptors
Cytoplasm
Proteins
Huntingtin Protein
2004

Np95 Is a Histone-Binding Protein Endowed with Ubiquitin Ligase Activity

Citterio, E., Papait, R., Nicassio, F., Vecchi, M., Gomiero, P., Mantovani, R., Di Fiore, P. P. & Bonapace, I. M., Mar 2004, In : Molecular and Cellular Biology. 24, 6, p. 2526-2535 10 p.

Research output: Contribution to journalArticle

Ligases
Ubiquitin
Histones
Carrier Proteins
Chromatin
2002

Differential nucleocytoplasmic trafficking between the related endocytic proteins Eps15 and Eps15R

Poupon, V., Polo, S., Vecchi, M., Martin, G., Dautry-Varsat, A., Cerf-Bensussan, N., Fiore, P. P. D. & Benmerah, A., Mar 15 2002, In : Journal of Biological Chemistry. 277, 11, p. 8941-8948 8 p.

Research output: Contribution to journalArticle

Nuclear Export Signals
Clathrin
Leucine
Proteins
Karyopherins
2001

Nucleocytoplasmic shuttling of endocytic proteins

Vecchi, M., Polo, S., Poupon, V., Van De Loo, J. W., Benmerah, A. & Di Fiore, P. P., Jun 26 2001, In : Journal of Cell Biology. 153, 7, p. 1511-1517 7 p.

Research output: Contribution to journalArticle

Endocytosis
Lymphoid Leukemia
Clathrin
Myeloid Leukemia
Cell Nucleus Active Transport
1999

Physiological requirement for both SH2 domains for phospholipase C-γ1 function and interaction with platelet-derived growth factor receptors

Ji, Q. S., Chattopadhyay, A., Vecchi, M. & Carpenter, G., Jul 1999, In : Molecular and Cellular Biology. 19, 7, p. 4961-4970 10 p.

Research output: Contribution to journalArticle

Platelet-Derived Growth Factor Receptors
src Homology Domains
Type C Phospholipases
Tyrosine
Intercellular Signaling Peptides and Proteins

The role of individual SH2 domains in mediating association of phospholipase C-γ1 with the activated EGF receptor

Chattopadhyay, A., Vecchi, M., Ji, Q. S., Mernaugh, R. & Carpenter, G., Sep 10 1999, In : Journal of Biological Chemistry. 274, 37, p. 26091-26097 7 p.

Research output: Contribution to journalArticle

src Homology Domains
Type C Phospholipases
Epidermal Growth Factor Receptor
Peptides
Phosphotyrosine
1998

Tyrosine phosphorylation and proteolysis: Pervanadate-induced, metalloprotease-dependent cleavage of the ErbB-4 receptor and amphiregulin

Vecchi, M., Rudolph-Owen, L. A., Brown, C. L., Dempsey, P. J. & Carpenter, G., Aug 7 1998, In : Journal of Biological Chemistry. 273, 32, p. 20589-20595 7 p.

Research output: Contribution to journalArticle

Proteolysis
Phosphorylation
Metalloproteases
Tyrosine
Protein Tyrosine Phosphatases
1997

Constitutive proteolysis of the ErbB-4 receptor tyrosine kinase by a unique, sequential mechanism

Vecchi, M. & Carpenter, G., Nov 17 1997, In : Journal of Cell Biology. 139, 4, p. 995-1003 9 p.

Research output: Contribution to journalArticle

Metalloproteases
Proteasome Endopeptidase Complex
Protein-Tyrosine Kinases
Proteolysis
Neuregulin-1
1996

Expression of acylphosphatase in Saccharomyces cerevisiae enhances ethanol fermentation rate

Raugei, G., Modesti, A., Magherini, F., Marzocchini, R., Vecchi, M. & Ramponi, G., 1996, In : Biotechnology and Applied Biochemistry. 23, 3, p. 273-278 6 p.

Research output: Contribution to journalArticle

Yeast
Fermentation
Saccharomyces cerevisiae
Ethanol
DNA sequences

Selective cleavage of the heregulin receptor ErbB-4 by protein kinase C activation

Vecchi, M., Baulida, J. & Carpenter, G., 1996, In : Journal of Biological Chemistry. 271, 31, p. 18989-18995 7 p.

Research output: Contribution to journalArticle

Neuregulin-1
Tetradecanoylphorbol Acetate
Protein Kinase C
Acetates
Chemical activation
1995

Properties of N-terminus truncated and C-terminus mutated muscle acylphosphatases

Taddei, N., Modesti, A., Bucciantini, M., Stefani, M., Magherini, F., Vecchi, M., Raugei, G. & Ramponi, G., Apr 3 1995, In : FEBS Letters. 362, 2, p. 175-179 5 p.

Research output: Contribution to journalArticle

Muscle
Muscles
Stabilization
Synthetic Genes
Kinetics
1994

Arginine-23 is involved in the catalytic site of muscle acylphosphatase

Taddei, N., Stefani, M., Vecchi, M., Modesti, A., Raugei, G., Bucciantini, M., Magherini, F. & Ramponi, G., Sep 21 1994, In : Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular. 1208, 1, p. 75-80 6 p.

Research output: Contribution to journalArticle

Arginine
Muscle
Catalytic Domain
Phosphates
Muscles

Expression of human acylphosphatase in Escherichia coli affects intracellular calcium levels

Liguri, G., Cecchi, C., Pieri, A., Raugei, G., Vecchi, M., Modesti, A., Nassi, P. & Ramponi, G., 1994, In : Biochemistry and Molecular Biology International. 34, 1, p. 109-117 9 p.

Research output: Contribution to journalArticle

Escherichia coli
Calcium
Cations
Rubidium
Synthetic Genes
1993

Chemical synthesis and expression of a gene coding for human muscle acylphosphatase

Modesti, A., Raugei, G., Taddei, N., Marzocchini, R., Vecchi, M., Camici, G., Manao, G. & Ramponi, G., Dec 14 1993, In : BBA - Gene Structure and Expression. 1216, 3, p. 369-374 6 p.

Research output: Contribution to journalArticle

DNA sequences
Muscle
Genes
Gene Expression
Muscles