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Research Output 1996 2019

  • 1896 Citations
  • 24 h-Index
  • 47 Article
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Article
2019
1 Citation (Scopus)

Neuromodulatory action of picomolar extracellular Aβ42 oligomers on presynaptic and postsynaptic mechanisms underlying synaptic function and memory

Gulisano, W., Melone, M., Ripoli, C., Tropea, M. R., Li Puma, D. D., Giunta, S., Cocco, S., Marcotulli, D., Origlia, N., Palmeri, A., Arancio, O., Conti, F., Grassi, C. & Puzzo, D., Jul 24 2019, In : Journal of Neuroscience. 39, 30, p. 5986-6000 15 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Brain
Post-Synaptic Density
Cyclic GMP-Dependent Protein Kinases
Calcium-Calmodulin-Dependent Protein Kinases
2018
3 Citations (Scopus)

Autosomal-dominant myopia associated to a novel P4HA2 missense variant and defective collagen hydroxylation

Napolitano, F., Di Iorio, V., Testa, F., Tirozzi, A., Reccia, M. G., Lombardi, L., Farina, O., Simonelli, F., Gianfrancesco, F., Di Iorio, G., Melone, M. A. B., Esposito, T. & Sampaolo, S., May 1 2018, In : Clinical Genetics. 93, 5, p. 982-991 10 p.

Research output: Contribution to journalArticle

Prolyl Hydroxylases
Myopia
Hydroxylation
Collagen
Peptides
Presynaptic Terminals
Synapses
Protein Isoforms
Aurothioglucose
Amino Acid Transport System X-AG
4 Citations (Scopus)

Hypoalbuminemia as a predictor of acute kidney injury during colistin treatment

Giacobbe, D. R., di Masi, A., Leboffe, L., Del Bono, V., Rossi, M., Cappiello, D., Coppo, E., Marchese, A., Casulli, A., Signori, A., Novelli, A., Perrone, K., Principe, L., Bandera, A., Vender, L. E., Misin, A., Occhilupo, P., Melone, M., Ascenzi, P., Gori, A. & 3 others, Luzzati, R., Viscoli, C. & Di Bella, S., Dec 1 2018, In : Scientific Reports. 8, 1, 11968.

Research output: Contribution to journalArticle

Colistin
Hypoalbuminemia
Acute Kidney Injury
Kidney Diseases
Serum Albumin
19 Citations (Scopus)

Interneuron-specific signaling evokes distinctive somatostatin-mediated responses in adult cortical astrocytes

Mariotti, L., Losi, G., Lia, A., Melone, M., Chiavegato, A., Gómez-Gonzalo, M., Sessolo, M., Bovetti, S., Forli, A., Zonta, M., Requie, L. M., Marcon, I., Pugliese, A., Viollet, C., Bettler, B., Fellin, T., Conti, F. & Carmignoto, G., Dec 1 2018, In : Nature Communications. 9, 1, 82.

Research output: Contribution to journalArticle

Interneurons
Somatostatin
Astrocytes
brain
Brain

The effect of amyloid-β peptide on synaptic plasticity and memory is influenced by different isoforms, concentrations, and aggregation status

Gulisano, W., Melone, M., Li Puma, D. D., Tropea, M. R., Palmeri, A., Arancio, O., Grassi, C., Conti, F. & Puzzo, D., Nov 2018, In : Neurobiology of Aging. 71, p. 51-60 10 p.

Research output: Contribution to journalArticle

Neuronal Plasticity
Long-Term Memory
Long-Term Potentiation
Amyloid
Protein Isoforms
2017
4 Citations (Scopus)

GAT-1 mediated GABA uptake in rat oligodendrocytes

Fattorini, G., Melone, M., Sánchez-Gómez, M. V., Arellano, R. O., Bassi, S., Matute, C. & Conti, F., Mar 1 2017, In : GLIA. 65, 3, p. 514-522 9 p.

Research output: Contribution to journalArticle

Oligodendroglia
gamma-Aminobutyric Acid
GABA Plasma Membrane Transport Proteins
GAT
Cell Size
7 Citations (Scopus)

In-vivo effects of knocking-down metabotropic glutamate receptor 5 in the SOD1G93A mouse model of amyotrophic lateral sclerosis

Bonifacino, T., Cattaneo, L., Gallia, E., Puliti, A., Melone, M., Provenzano, F., Bossi, S., Musante, I., Usai, C., Conti, F., Bonanno, G. & Milanese, M., Jun 21 2017, In : Neuropharmacology. 123, p. 433-445 13 p.

Research output: Contribution to journalArticle

Metabotropic Glutamate 5 Receptor
Amyotrophic Lateral Sclerosis
Motor Neurons
Glutamic Acid
Disease Progression
2016

Defective glutamate and K+ clearance by cortical astrocytes in familial hemiplegic migraine type 2

Capuani, C., Melone, M., Tottene, A., Bragina, L., Crivellaro, G., Santello, M., Casari, G. N., Conti, F. & Pietrobon, D., Aug 1 2016, In : EMBO Molecular Medicine. 8, 8, p. 967-986 20 p.

Research output: Contribution to journalArticle

Cortical Spreading Depression
Migraine Disorders
Astrocytes
Glutamic Acid
Amino Acid Transport System X-AG
35 Citations (Scopus)

Defective glutamate and K+ clearance by cortical astrocytes in familial hemiplegic migraine type 2

Capuani, C., Melone, M., Tottene, A., Bragina, L., Crivellaro, G., Santello, M., Casari, G., Conti, F. & Pietrobon, D., Aug 1 2016, In : EMBO Molecular Medicine. 8, 8, p. 967-986 20 p.

Research output: Contribution to journalArticle

Cortical Spreading Depression
Migraine Disorders
Astrocytes
Glutamic Acid
Amino Acid Transport System X-AG
2015
19 Citations (Scopus)

A quantitative analysis of cellular and synaptic localization of GAT-1 and GAT-3 in rat neocortex

Melone, M., Ciappelloni, S. & Conti, F., Mar 1 2015, In : Brain Structure and Function. 220, 2, p. 885-897 13 p.

Research output: Contribution to journalArticle

Neocortex
Synapses
GAT
Cerebral Cortex
gamma-Aminobutyric Acid
2014
23 Citations (Scopus)

Knocking down metabotropic glutamate receptor 1 improves survival and disease progression in the SOD1G93A mouse model of amyotrophic lateral sclerosis

Milanese, M., Giribaldi, F., Melone, M., Bonifacino, T., Musante, I., Carminati, E., Rossi, P. I. A., Vergani, L., Voci, A., Conti, F., Puliti, A. & Bonanno, G., Apr 2014, In : Neurobiology of Disease. 64, p. 48-59 12 p.

Research output: Contribution to journalArticle

Amyotrophic Lateral Sclerosis
Disease Progression
Survival
Glutamic Acid
Motor Neurons
5 Citations (Scopus)

Plasma membrane transporters GAT-1 and GAT-3 contribute to heterogeneity of GABAergic synapses in neocortex

Melone, M., Ciappelloni, S. & Conti, F., Jul 25 2014, In : Frontiers in Neuroanatomy. 8, JULY, 72.

Research output: Contribution to journalArticle

GABA Plasma Membrane Transport Proteins
Membrane Transport Proteins
Neocortex
Synapses
Cell Membrane
2012
25 Citations (Scopus)

Analysis of synaptotagmin, SV2, and Rab3 expression in cortical glutamatergic and GABAergic axon terminals

Bragina, L., Fattorini, G., Giovedi, S., Melone, M., Bosco, F., Benfenati, F. & Conti, F., 2012, In : Frontiers in Cellular Neuroscience. JANUARY, 32.

Research output: Contribution to journalArticle

rab3 GTP-Binding Proteins
Synaptotagmins
Synaptic Vesicles
Presynaptic Terminals
Synaptotagmin II
2011
16 Citations (Scopus)

A role for GAT-1 in presynaptic GABA homeostasis?

Conti, F., Melone, M., Fattorini, G., Bragina, L. & Ciappelloni, S., Apr 5 2011, In : Frontiers in Cellular Neuroscience. APRIL, p. 10 1 p.

Research output: Contribution to journalArticle

gamma-Aminobutyric Acid
Homeostasis
Membrane Transport Proteins
Neurotransmitter Transport Proteins
Cell Membrane
24 Citations (Scopus)

Cellular and synaptic localization of EAAT2a in human cerebral cortex

Melone, M., Bellesi, M., Ducati, A., Iacoangeli, M. & Conti, F., Jan 14 2011, In : Frontiers in Neuroanatomy. JAN, p. 1-14 14 p.

Research output: Contribution to journalArticle

Presynaptic Terminals
Cerebral Cortex
Astrocytes
Synapses
Axons
2010
24 Citations (Scopus)

GLT-1 promoter activity in astrocytes and neurons of mouse hippocampus and somatic sensory cortex

de Vivo, L., Melone, M., Rothstein, J. D. & Conti, F., Jan 11 2010, In : Frontiers in Neuroanatomy. 3, JAN, 31.

Research output: Contribution to journalArticle

Astrocytes
Hippocampus
Neurons
Hippocampal CA3 Region
Neocortex
10 Citations (Scopus)

Quantitative analysis of EAAT4 promoter activity in neurons and astrocytes of mouse somatic sensory cortex

de Vivo, L., Melone, M., Bucci, G., Rothstein, J. D. & Conti, F., Apr 2010, In : Neuroscience Letters. 474, 1, p. 42-45 4 p.

Research output: Contribution to journalArticle

Astrocytes
Neurons
Cerebral Cortex
Fluorescence
Purkinje Cells
2009
3 Citations (Scopus)

Acute phencyclidine administration reduces extracellular glutamate levels and the expression of synaptophysin and SNAP-25 in rat frontal cortex

Fattorini, G., Bragina, L., Candiracci, C., Melone, M., Cozzi, A., Pellegrini-Giampietro, D. E. & Conti, F., Mar 2009, In : Schizophrenia Research. 108, 1-3, p. 288-289 2 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

GLT-1 up-regulation enhances the effect of PCP on prepulse inhibition of the startle reflex in adult rats

Melone, M., Bellesi, M., Gubbini, A. & Conti, F., Apr 2009, In : Schizophrenia Research. 109, 1-3, p. 196-197 2 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

GLT-1 upregulation impairs prepulse inhibition of the startle reflex in adult rats

Bellesi, M., Melone, M., Gubbini, A., Battistacci, S. & Conti, F., 2009, In : GLIA. 57, 7, p. 703-713 11 p.

Research output: Contribution to journalArticle

Startle Reflex
Up-Regulation
Ceftriaxone
Amino Acid Transport System X-AG
Automatic Data Processing
54 Citations (Scopus)

Synaptic localization of GLT-1a in the rat somatic sensory cortex

Melone, M., Bellesi, M. & Conti, F., Jan 1 2009, In : GLIA. 57, 1, p. 108-117 10 p.

Research output: Contribution to journalArticle

Presynaptic Terminals
Synapses
Gold
Electron Microscopy
Amino Acid Transport System X-AG
60 Citations (Scopus)

Up-regulation of GLT-1 severely impairs LTD at mossy fibre-CA3 synapses

Omrani, A., Melone, M., Bellesi, M., Safiulina, V., Aida, T., Tanaka, K., Cherubini, E. & Conti, F., Oct 2009, In : Journal of Physiology. 587, 19, p. 4575-4588 14 p.

Research output: Contribution to journalArticle

Ceftriaxone
Gold
Synapses
Amino Acid Transport System X-AG
Glutamic Acid
37 Citations (Scopus)

VGLUT1 and VGAT are sorted to the same population of synaptic vesicles in subsets of cortical axon terminals

Fattorini, G., Verderio, C., Melone, M., Giovedì, S., Benfenati, F., Matteoli, M. & Conti, F., Sep 2009, In : Journal of Neurochemistry. 110, 5, p. 1538-1546 9 p.

Research output: Contribution to journalArticle

Synaptic Vesicles
Physiology
Presynaptic Terminals
Synapses
gamma-Aminobutyric Acid
2008
24 Citations (Scopus)

GLT-1 expression and Glu uptake in rat cerebral cortex are increased by phencyclidine

Fattorini, G., Melone, M., Bragina, L., Candiracci, C., Cozzi, A., Giampietro, D. E. P., Torres-Ramos, M., Pérez-Samartín, A., Matute, C. & Conti, F., Sep 2008, In : GLIA. 56, 12, p. 1320-1327 8 p.

Research output: Contribution to journalArticle

Phencyclidine
Cerebral Cortex
Glutamic Acid
Amino Acid Transport System X-AG
Microdialysis
2007
7 Citations (Scopus)
2006
27 Citations (Scopus)

GLT-1 down-regulation induced by clozapine in rat frontal cortex is associated with synaptophysin up-regulation

Bragina, L., Melone, M., Fattorini, G., Torres-Ramos, M., Vallejo-Illarramendi, A., Matute, C. & Conti, F., Oct 2006, In : Journal of Neurochemistry. 99, 1, p. 134-141 8 p.

Research output: Contribution to journalArticle

Vesicular Glutamate Transport Protein 1
Synaptophysin
Clozapine
Frontal Lobe
Synaptosomes
24 Citations (Scopus)

Localization of the Na+-coupled neutral amino acid transporter 2 in the cerebral cortex

Melone, M., Varoqui, H., Erickson, J. D. & Conti, F., 2006, In : Neuroscience. 140, 1, p. 281-292 12 p.

Research output: Contribution to journalArticle

Neutral Amino Acid Transport Systems
Cerebral Cortex
Synaptophysin
Glutamine
42 Citations (Scopus)

The glutamine commute: Lost in the tube?

Conti, F. & Melone, M., May 2006, In : Neurochemistry International. 48, 6-7, p. 459-464 6 p.

Research output: Contribution to journalArticle

Presynaptic Terminals
Glutamine
Glutamic Acid
Astrocytes
Neurons
2005
45 Citations (Scopus)

Clozapine reduces GLT-1 expression and glutamate uptake in astrocyte cultures

Vallejo-Illarramendi, A., Torres-Ramos, M., Melone, M., Conti, F. & Matute, C., May 2005, In : GLIA. 50, 3, p. 276-279 4 p.

Research output: Contribution to journalArticle

Amino Acid Transport System X-AG
Clozapine
Astrocytes
Glutamic Acid
Cerebral Cortex
99 Citations (Scopus)

Increased expression of the astrocytic glutamate transporter GLT-1 in the prefrontal cortex of schizophrenics

Matute, C., Melone, M., Vallejo-Illarramendi, A. & Conti, F., Feb 2005, In : GLIA. 49, 3, p. 451-455 5 p.

Research output: Contribution to journalArticle

Amino Acid Transport System X-AG
Prefrontal Cortex
Messenger RNA
Glutamic Acid
Xenopus
81 Citations (Scopus)

Light microscopic identification and immunocytochemical characterization of glutamatergic synapses in brain sections

Melone, M., Burette, A. & Weinberg, R. J., Nov 28 2005, In : Journal of Comparative Neurology. 492, 4, p. 495-509 15 p.

Research output: Contribution to journalArticle

Vesicular Glutamate Transport Protein 1
Synapses
Staining and Labeling
Light
Brain
12 Citations (Scopus)

Neuronal localization of the GABA transporter GAT-3 in human cerebral cortex: A procedural artifact?

Melone, M., Barbaresi, P., Fattorini, G. & Conti, F., Jul 2005, In : Journal of Chemical Neuroanatomy. 30, 1, p. 45-54 10 p.

Research output: Contribution to journalArticle

Amino Acid Transport Systems
Butyric Acid
Membrane Transport Proteins
Cerebral Cortex
Artifacts
2004
244 Citations (Scopus)

GABA transporters in the mammalian cerebral cortex: Localization, development and pathological implications

Conti, F., Minelli, A. & Melone, M., Jul 2004, In : Brain Research Reviews. 45, 3, p. 196-212 17 p.

Research output: Contribution to journalArticle

GABA Plasma Membrane Transport Proteins
Cerebral Cortex
gamma-Aminobutyric Acid
Synapses
Aminobutyrates
49 Citations (Scopus)

Localization of the Glutamine Transporter SNAT1 in Rat Cerebral Cortex and Neighboring Structures, with a Note on its Localization in Human Cortex

Melone, M., Quagliano, F., Barbaresi, P., Varoqui, H., Erickson, J. D. & Conti, F., May 2004, In : Cerebral Cortex. 14, 5, p. 562-574 13 p.

Research output: Contribution to journalArticle

Aminobutyrates
Glutamine
Cerebral Cortex
Neurons
Synaptophysin
31 Citations (Scopus)

Perisomatic glutamatergic axon terminals: A novel feature of cortical synaptology revealed by vesicular glutamate transporter 1 immunostaining

Alonso-Nanclares, L., Minelli, A., Melone, M., Edwards, R. H., Defelipe, J. & Conti, F., 2004, In : Neuroscience. 123, 2, p. 547-556 10 p.

Research output: Contribution to journalArticle

Vesicular Glutamate Transport Protein 1
Pyramidal Cells
Presynaptic Terminals
Synapses
Carisoprodol
2003
26 Citations (Scopus)
18 Citations (Scopus)

Transient focal ischemia triggers neuronal expression of GAT-3 in the rat perilesional cortex

Melone, M., Cozzi, A., Pellegrini-Giampietro, D. E. & Conti, F., Oct 2003, In : Neurobiology of Disease. 14, 1, p. 120-132 13 p.

Research output: Contribution to journalArticle

Ischemia
Immunoblotting
Aminobutyrates
GAT
HSP70 Heat-Shock Proteins
2001
85 Citations (Scopus)

The expression of glutamate transporter GLT-1 in the rat cerebral cortex is down-regulated by the antipsychotic drug clozapine

Melone, M., Vitellaro-Zuccarello, L., Vallejo-Illarramendi, A., Pérez-Samartin, A., Matute, C., Cozzi, A., Pellegrini-Giampietro, D. E., Rothstein, J. D. & Conti, F., 2001, In : Molecular Psychiatry. 6, 4, p. 380-386 7 p.

Research output: Contribution to journalArticle

Amino Acid Transport System X-AG
Clozapine
Cerebral Cortex
Antipsychotic Agents
Glutamic Acid
2000
2 Citations (Scopus)

Etorphine increases the number of μ-opioid receptor-positive cells in the cerebral cortex

Melone, M., Brecha, N. C., Sternini, C., Evans, C. & Conti, F., Sep 27 2000, In : Neuroscience. 100, 3, p. 439-443 5 p.

Research output: Contribution to journalArticle

Etorphine
Opioid Receptors
Cerebral Cortex
Neuropil
Narcotic Antagonists
1999
78 Citations (Scopus)
GABA Plasma Membrane Transport Proteins
Aminobutyrates
Membrane Transport Proteins
Neuroglia
Cerebral Cortex
78 Citations (Scopus)

Neuronal and glial localization of NR1 and NR2A/B subunits of the NMDA receptor in the human cerebral cortex

Conti, F., Barbaresi, P., Melone, M. & Ducati, A., 1999, In : Cerebral Cortex. 9, 2, p. 110-120 11 p.

Research output: Contribution to journalArticle

D-Aspartic Acid
Neuroglia
Cerebral Cortex
Dendritic Spines
Presynaptic Terminals
1998
169 Citations (Scopus)

EAAC1, a high-affinity glutamate transporter, is localized to astrocytes and gabaergic neurons besides pyramidal cells in the rat cerebral cortex

Conti, F., DeBiasi, S., Minelli, A., Rothstein, J. D. & Melone, M., 1998, In : Cerebral Cortex. 8, 2, p. 108-116 9 p.

Research output: Contribution to journalArticle

Amino Acid Transport System X-AG
GABAergic Neurons
Pyramidal Cells
Astrocytes
Cerebral Cortex
108 Citations (Scopus)
Aminobutyrates
Membrane Transport Proteins
Neuroglia
Cerebral Cortex
gamma-Aminobutyric Acid
1997
66 Citations (Scopus)

Neuronal and glial localization of NMDA receptors in the cerebral cortex

Conti, F., Minelli, A., DeBiasi, S. & Melone, M., Feb 1997, In : Molecular Neurobiology. 14, 1-2, p. 1-18 18 p.

Research output: Contribution to journalArticle

N-Methyl-D-Aspartate Receptors
Neuroglia
Cerebral Cortex
N-Methylaspartate
Dendritic Spines
1996
107 Citations (Scopus)

Expression of NR1 and NR2A/B subunits of the NMDA receptor in cortical astrocytes

Conti, F., DeBiasi, S., Minelli, R. & Melone, M., Jul 1996, In : GLIA. 17, 3, p. 254-258 5 p.

Research output: Contribution to journalArticle

N-Methyl-D-Aspartate Receptors
Astrocytes
N-Methylaspartate
Ionotropic Glutamate Receptors
Glutamate Receptors
67 Citations (Scopus)

Presynaptic NMDA receptors in the neocortex are both auto- and heteroreceptors

DeBiasi, S., Minelli, A., Melone, M. & Conti, F., 1996, In : NeuroReport. 7, 15-17, p. 2773-2776 4 p.

Research output: Contribution to journalArticle

Autoreceptors
Neocortex
Presynaptic Terminals
N-Methyl-D-Aspartate Receptors
Cerebral Cortex