• 3720 Citations
  • 32 h-Index
1979 …2017
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Research Output 1979 2017

  • 3720 Citations
  • 32 h-Index
  • 85 Article
  • 3 Conference contribution
  • 2 Chapter
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Article
16 Citations (Scopus)

111In-labeled 1,4,7,10-tetraazacyclododecane- N,N′,N″,N‴-tetraacetic acid-Lys8-vasotocin: A new powerful radioligand for oxytocin receptor-expressing tumors

Bussolati, G., Chinol, M., Chini, B., Nacca, A., Cassoni, P. & Paganelli, G., Jun 1 2001, In : Cancer Research. 61, 11, p. 4393-4397 5 p.

Research output: Contribution to journalArticle

Oxytocin Receptors
Vasotocin
Acids
Glioblastoma
Breast Neoplasms
90 Citations (Scopus)

90Y-DOTA-D-Phe1-Try3-octreotide in therapy of neuroendocrine malignancies

Paganelli, G., Bodei, L., Handkiewicz Junak, D., Rocca, P., Papi, S., Lopera Sierra, M., Gatti, M., Chinol, M., Bartolomei, M., Fiorenza, M. & Grana, C., 2002, In : Biopolymers. 66, 6, p. 393-398 6 p.

Research output: Contribution to journalArticle

Octreotide
Tumors
Neuroendocrine Tumors
Somatostatin
Neoplasms
7 Citations (Scopus)

Accurate determination of half-life and radionuclidic purity of reactor produced 177gLu (177mLu) for metabolic radiotherapy

Canella, L., Bonardi, M. L., Groppi, F., Persico, E., Zona, C., Menapace, E., Alfassi, Z. B., Chinol, M., Papi, S. & Tosi, G., Jun 2008, In : Journal of Radioanalytical and Nuclear Chemistry. 276, 3, p. 813-818 6 p.

Research output: Contribution to journalArticle

Nuclear medicine
Radiotherapy
Nuclear reactors
Radioisotopes
Ground state
1 Citation (Scopus)

Acquisition protocol for breast cancer imaging with technetium-99m-labeled synthetic peptide and technetium-99m-MDP

Fiorenza, M., Prisco, G., Bartolomei, M., Chinol, M., Cremonesi, M., Leonardi, L., De Cicco, C. & Paganelli, G., Sep 1997, In : Journal of Nuclear Medicine Technology. 25, 3, p. 191-194 4 p.

Research output: Contribution to journalArticle

Technetium
Breast Neoplasms
Peptides
Technetium Tc 99m Medronate
Breast
23 Citations (Scopus)

Adoptive immunotherapy by avidin-driven cytotoxic T lymphocyte-tumor bridging

Guttinger, M., Guidi, F., Chinol, M., Reali, E., Veglia, F., Viale, G., Paganelli, G., Corti, A. & Siccardi, A. G., 2000, In : Cancer Research. 60, 15, p. 4211-4215 5 p.

Research output: Contribution to journalArticle

Adoptive Immunotherapy
Avidin
Cytotoxic T-Lymphocytes
Neoplasms
T-Lymphocytes
41 Citations (Scopus)

A new biotin derivative-DOTA conjugate as a candidate for pretargeted diagnosis and therapy of tumors

Sabatino, G., Chinol, M., Paganelli, G., Papi, S., Chelli, M., Leone, G., Papini, A. M., De Luca, A. & Ginanneschi, M., Jul 3 2003, In : Journal of Medicinal Chemistry. 46, 14, p. 3170-3173 4 p.

Research output: Contribution to journalArticle

Biotinidase
Avidin
Carbon Monoxide
Chelating Agents
Biotin
182 Citations (Scopus)

Antibody-guided three-step therapy for high grade glioma with yttrium-90 biotin

Paganelli, G., Grana, C., Chinol, M., Cremonesi, M., De Cicco, C., De Braud, F., Robertson, C., Zurrida, S., Casadio, C., Zoboli, S., Siccardi, A. G. & Veronesi, U., 1999, In : European Journal Of Nuclear Medicine. 26, 4, p. 348-357 10 p.

Research output: Contribution to journalArticle

Yttrium
Biotin
Glioma
Antibodies
Avidin
16 Citations (Scopus)

AvidinOX™ for highly efficient tissue-pretargeted radionuclide therapy

De Santis, R., Leoni, B., Rosi, A., Albertoni, C., Forni, G., Cojoca, R., Iezzi, M., Musiani, P., Paganelli, G., Chinol, M. & Carminati, P., Apr 1 2010, In : Cancer Biotherapy and Radiopharmaceuticals. 25, 2, p. 143-148 6 p.

Research output: Contribution to journalArticle

Avidin
Radioisotopes
Biotin
Therapeutics
Schiff Bases
100 Citations (Scopus)

Biochemical modifications of avidin improve pharmacokinetics and biodistribution, and reduce immunogenicity

Chinol, M., Casalini, P., Maggiolo, M., Canevari, S., Omodeo, E. S., Caliceti, P., Veronese, F. M., Cremonesi, M., Chiolerio, F., Nardone, E., Siccardi, A. G. & Paganelli, G., 1998, In : British Journal of Cancer. 78, 2, p. 189-197 9 p.

Research output: Contribution to journalArticle

Avidin
Pharmacokinetics
Biotin
Half-Life
Injections
25 Citations (Scopus)

Biodistribution in tumour-bearing mice of two 90Y-labelled biotins using three-step tumour targeting

Chinol, M., Paganelli, G., Sudati, F., Meares, C. & Fazio, F., 1997, In : Nuclear Medicine Communications. 18, 2, p. 176-182 7 p.

Research output: Contribution to journalArticle

Biotin
Pentetic Acid
Neoplasms
Injections
Avidin
143 Citations (Scopus)

Biokinetics and dosimetry in patients administered with 111In-DOTA-Tyr3-octreotide: Implications for internal radiotherapy with 90Y-DOTATOC

Cremonesi, M., Ferrari, M., Zoboli, S., Chinol, M., Stabin, M. G., Orsi, F., Maecke, H. R., Jermann, E., Robertson, C., Fiorenza, M., Tosi, G. & Paganelli, G., 1999, In : European Journal Of Nuclear Medicine. 26, 8, p. 877-886 10 p.

Research output: Contribution to journalArticle

Octreotide
Radiotherapy
Spleen
Kidney
Neoplasms
6 Citations (Scopus)

Biotin derivatives carrying two chelating DOTA units. Synthesis, in vitro evaluation of biotinidases resistance, avidin binding, and radiolabeling tests

Pratesi, A., Bucelli, F., Mori, I., Chinol, M., Verdoliva, A., Paganelli, G., Rivieccio, V., Gariboldi, L. & Ginanneschi, M., 2010, In : Journal of Medicinal Chemistry. 53, 1, p. 432-440 9 p.

Research output: Contribution to journalArticle

Biotinidase
Avidin
Biotin
Lysine
4-Aminobenzoic Acid
92 Citations (Scopus)

Chemistry and biological behavior of samarium-153 and rhenium-186-labeled hydroxyapatite particles: Potential radiopharmaceuticals for radiation synovectomy

Chinol, M., Vallabhajosula, S., Goldsmith, S. J., Klein, M. J., Deutsch, K. F., Chinen, L. K., Brodack, J. W., Deutsch, E. A., Watson, B. A. & Tofe, A. J., 1993, In : Journal of Nuclear Medicine. 34, 9, p. 1536-1542 7 p.

Research output: Contribution to journalArticle

Samarium
Rhenium
Radiopharmaceuticals
Durapatite
Radiation
2 Citations (Scopus)

Clinical applications of radiolabeled monoclonal antibodies for cancer diagnosis and therapy

Paganelli, G. & Chinol, M., 1998, In : Minerva Biotecnologica. 10, 4, p. 146-161 16 p.

Research output: Contribution to journalArticle

Monoclonal antibodies
Tumors
Monoclonal Antibodies
Radioactivity
Dosimetry
33 Citations (Scopus)

Clinical validation of the avidin/indium-111 biotin approach for imaging infection/inflammation in orthopaedic patients

Lazzeri, E., Manca, M., Molea, N., Marchetti, S., Consoli, V., Bodei, L., Bianchi, R., Chinol, M., Paganelli, G. & Mariani, G., 1999, In : European Journal Of Nuclear Medicine. 26, 6, p. 606-614 9 p.

Research output: Contribution to journalArticle

Indium
Avidin
Technetium Tc 99m Exametazime
Biotin
Radionuclide Imaging
34 Citations (Scopus)
Oropharyngeal Neoplasms
Radioimmunotherapy
Radiotherapy
Biotin
Radio
4 Citations (Scopus)
3 Citations (Scopus)

Design and solid phase synthesis of new DOTA conjugated (+)-biotin dimers planned to develop molecular weight-tuned avidin oligomers

Pratesi, A., Ginanneschi, M., Melani, F., Chinol, M., Carollo, A., Paganelli, G., Lumini, M., Bartoli, M., Frediani, M., Rosi, L., Petrucci, G., Messori, L. & Papini, A. M., Apr 7 2015, In : Organic and Biomolecular Chemistry. 13, 13, p. 3988-4001 14 p.

Research output: Contribution to journalArticle

Solid-Phase Synthesis Techniques
biotin
Avidin
Biotin
oligomers
24 Citations (Scopus)

Dosimetric model for locoregional treatments of brain tumors with 90Y-conjugates: Clinical application with 90Y-DOTATOC

Ferrari, M., Cremonesi, M., Bartolomei, M., Bodei, L., Chinol, M., Fiorenza, M., Tosi, G. & Paganelli, G., Jan 1 2006, In : Journal of Nuclear Medicine. 47, 1, p. 105-112 8 p.

Research output: Contribution to journalArticle

Brain Neoplasms
Brain
Therapeutics
Octreotide
DOTA-Tyr(3)-90Y-octreotide
20 Citations (Scopus)

Dosimetry in radionuclide therapies with 90Y-conjugates: The IEO experience

Cremonesi, M., Ferrari, M., Chinol, M., Bartolomei, M., Stabin, M. G., Sacco, E., Fiorenza, M., Tosi, G. & Paganelli, G., 2000, In : Quarterly Journal of Nuclear Medicine. 44, 4, p. 325-332 8 p.

Research output: Contribution to journalArticle

Radioisotopes
Radioimmunotherapy
Radiopharmaceuticals
Pharmacokinetics
Biotin
31 Citations (Scopus)

Effect of blood-brain barrier and blood-tumor barrier modification on central nervous system liposomal uptake

Gennuso, R., Spigelman, M. K., Chinol, M., Zappulla, R. A., Nieves, J., Vallabhajosula, S., Paciucci, P. A., Goldsmith, S. J. & Holland, J. F., 1993, In : Cancer Investigation. 11, 2, p. 118-128 11 p.

Research output: Contribution to journalArticle

Blood-Brain Barrier
Central Nervous System Neoplasms
Central Nervous System
Etoposide
Liposomes
5 Citations (Scopus)

Eleven-year experience with the avidin-biotin pretargeting system in glioblastoma: Toxicity, efficacy and survival

Grana, C. M., Chinol, M., de Cicco, C., Bartolomei, M., Cremonesi, M., Bodei, L., Rocca, P. A., Pacifici, M., Tiberini, S., Baio, S. M., Broggi, G., Severi, S. & Paganelli, G., 2012, In : Open Nuclear Medicine Journal. 4, p. 14-20 7 p.

Research output: Contribution to journalArticle

Avidin
Glioblastoma
Biotin
Survival
Radioimmunotherapy

El sistema avidina-biotina y su aplicacion en la oncologia nuclear

Translated title of the contribution: The avidin-biotin and its application in nuclear oncologyOliva, J. P., Pimentel, G., Cromenesi, M., Chinol, M., Fiorenza, M., Prisco, G., Siccardi, A. G. & Paganelli, G., 1997, In : Revista Espanola de Medicina Nuclear. 16, 4, p. 279-288 10 p.

Research output: Contribution to journalArticle

Avidin
Nuclear Medicine
Biotin
Italy
Monoclonal Antibodies
39 Citations (Scopus)

Evaluation of a new biotin-DOTA conjugate for pretargeted antibody-guided radioimmunotherapy (PAGRIT®)

Urbano, N., Papi, S., Ginanneschi, M., De Santis, R., Pace, S., Lindstedt, R., Ferrari, L., Choi, S., Paganelli, G. & Chinol, M., Jan 2007, In : European Journal of Nuclear Medicine and Molecular Imaging. 34, 1, p. 68-77 10 p.

Research output: Contribution to journalArticle

Radioimmunotherapy
Avidin
Antibodies
Ascorbic Acid
Neoplasms
4 Citations (Scopus)

Evaluation of four radiopharmaceuticals for imaging inflammation in a rabbit model of arthritis

Chinol, M., Vallabhajosula, S., Goldsmith, S. J., Paganelli, G. & Palestro, C. J., Sep 1996, In : Annals of Nuclear Medicine. 10, 3, p. 287-291 5 p.

Research output: Contribution to journalArticle

Radiopharmaceuticals
Arthritis
Knee
Rabbits
Inflammation
7 Citations (Scopus)

Evaluation of fresh and old eluate of 99Mo/99mTc generators used for labeling of different pharmaceutical kits

Urbano, N., Modoni, S., Guerra, M. & Chinol, M., Jun 2005, In : Journal of Radioanalytical and Nuclear Chemistry. 265, 1, p. 7-10 4 p.

Research output: Contribution to journalArticle

Radiopharmaceuticals
Drug products
Labeling
Pharmaceutical Preparations
Radioactivity
10 Citations (Scopus)

Facts and myths about radiopeptide therapy: Scylla, Charybdis and Sibyl [2]

Bodei, L., Chinol, M., Cremonesi, M. & Paganelli, G., 2002, In : European Journal Of Nuclear Medicine. 29, 8, p. 1099-1100 2 p.

Research output: Contribution to journalArticle

83 Citations (Scopus)

Generator-produced Yttrium-90 for radioimmunotherapy

Chinol, M. & Hnatowich, D. J., 1987, In : Journal of Nuclear Medicine. 28, 9, p. 1465-1471 7 p.

Research output: Contribution to journalArticle

Radioimmunotherapy
Yttrium
Pentetic Acid
Edetic Acid
Antibodies
30 Citations (Scopus)
B-Cell Lymphoma
Non-Hodgkin's Lymphoma
Blood Cells
Stem Cells
Stem Cell Transplantation
1 Citation (Scopus)

High-performance liquid chromatographic determination of phosphocreatinine and creatinine in pharmaceutical preparations

Ballerini, R., Chinol, M. & Cambi, A., Nov 21 1979, In : Journal of Chromatography A. 179, 2, p. 365-369 5 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Improved radiotracing of oxytocin receptor-expressing tumours using the new [111 In]-DOTA-Lys8-deamino-vasotocin analogue

Chini, B., Chinol, M., Cassoni, P., Papi, S., Reversi, A., Areces, L., Marrocco, T., Paganelli, G., Manning, M. & Bussolati, G., Sep 1 2003, In : British Journal of Cancer. 89, 5, p. 930-936 7 p.

Research output: Contribution to journalArticle

Oxytocin Receptors
Vasotocin
Oxytocin
Neoplasms
Vasopressin Receptors
4 Citations (Scopus)
Radioimmunodetection
Melanoma-Specific Antigens
Rhenium
Radioimmunotherapy
Anti-Idiotypic Antibodies
20 Citations (Scopus)

Intraoperative avidination for radionuclide therapy: A prospective new development to accelerate radiotherapy in breast cancer

Paganelli, G., Ferrari, M., Ravasi, L., Cremonesi, M., De Cicco, C., Galimberti, V., Sivolapenko, G., Luini, A., De Santis, R., Travaini, L. L., Fiorenza, M., Chinol, M., Papi, S., Zanna, C., Carminati, P. & Veronesi, U., Sep 15 2007, In : Clinical Cancer Research. 13, 18

Research output: Contribution to journalArticle

Radioisotopes
Breast
Radiotherapy
Avidin
Breast Neoplasms
35 Citations (Scopus)
Breast Neoplasms
Lymphoscintigraphy
Coloring Agents
Colloids
Dissection
5 Citations (Scopus)

In vitro and in vivo studies with no-carrier added radioiodinated MIBG.

Franceschini, R., Pecorale, A., Chinol, M., Calcagni, M. L., Servidei, T., Riccardi, R. & Troncone, L., Dec 1995, In : Quarterly Journal of Nuclear Medicine. 39, 4 Suppl 1, p. 72-77 6 p.

Research output: Contribution to journalArticle

3-Iodobenzylguanidine
In Vitro Techniques
High Pressure Liquid Chromatography
Radiopharmaceuticals
Neuroblastoma
14 Citations (Scopus)
Radioisotopes
Radioactivity
Joints
ferric hydroxide
Knee
13 Citations (Scopus)

Localization of Avidin in Superficial Bladder Cancer: A Potentially New Approach for Radionuclide Therapy

Chinol, M., De Cobelli, O., Trifirò, G., Scardino, E., Bartolomei, M., Verweij, F., Papi, S., Matei, D. V. & Paganelli, G., Nov 2003, In : European Urology. 44, 5, p. 556-559 4 p.

Research output: Contribution to journalArticle

Avidin
Urinary Bladder Neoplasms
Radioisotopes
Biotin
Intravesical Administration
17 Citations (Scopus)

Low and high tenascin-expressing tumors are efficiently targeted by ST2146 monoclonal antibody

De Santis, R., Albertoni, C., Petronzelli, F., Campo, S., D'Alessio, V., Rosi, A., Anastasi, A. M., Lindstedt, R., Caroni, N., Arseni, B., Chiodi, P., Verdoliva, A., Cassani, G., Chinol, M., Paganelli, G. & Carminati, P., Apr 1 2006, In : Clinical Cancer Research. 12, 7 I, p. 2191-2196 6 p.

Research output: Contribution to journalArticle

Tenascin
Monoclonal Antibodies
Neoplasms
Radioimmunotherapy
Glioblastoma
3 Citations (Scopus)

Lutetium-177 labeled peptides: The European institute of oncology experience

Carollo, A., Papi, S. & Chinol, M., Jan 1 2016, In : Current Radiopharmaceuticals. 9, 1, p. 19-32 14 p.

Research output: Contribution to journalArticle

Lutetium
Somatostatin Receptors
Peptides
Radioisotopes
Neoplasms
13 Citations (Scopus)

New radiopharmaceutical agents for the treatment of castration-resistant prostate cancer

Maffioli, L., Florimonte, L., Costa, D. C., Castanheira, J. C., Grana, C., Luster, M., Bodei, L. & Chinol, M., Dec 1 2015, In : Quarterly Journal of Nuclear Medicine and Molecular Imaging. 59, 4, p. 420-438 19 p.

Research output: Contribution to journalArticle

Radiopharmaceuticals
Castration
Prostatic Neoplasms
Bone and Bones
Bombesin Receptors
31 Citations (Scopus)

Novel antitenascin antibody with increased tumour localisation for Pretargeted Antibody-Guided RadioimmunoTherapy (PAGRITR)

De Santis, R., Anastasi, A. M., D'Alessio, V., Pelliccia, A., Albertoni, C., Rosi, A., Leoni, B., Lindstedt, R., Petronzelli, F., Dani, M., Verdoliva, A., Ippolito, A., Campanile, N., Manfredi, V., Esposito, A., Cassani, G., Chinol, M., Paganelli, G. & Carminati, P., Apr 7 2003, In : British Journal of Cancer. 88, 7, p. 996-1003 8 p.

Research output: Contribution to journalArticle

Radioimmunotherapy
Hybridomas
Monoclonal Antibodies
Antibodies
Epitopes
6 Citations (Scopus)

Optimization of antibody labeling with rhenium-188 using a prelabeled MAG3 chelate

Crudo, J. L., Edreira, M. M., Obenaus, E. R., Chinol, M., Paganelli, G. & De Castiglia, S. G., Nov 6 2002, In : International Journal of Pharmaceutics. 248, 1-2, p. 173-182 10 p.

Research output: Contribution to journalArticle

Rhenium
Immunoglobulin G
Inflammation
Antibodies
Protein Stability
21 Citations (Scopus)

Optimization of axillary lymphoscintigraphy to detect the sentinel node in breast cancer

De Cicco, C., Cremonesi, M., Chinol, M., Bartolomei, M., Pizzamiglio, M., Leonardi, L., Fiorenza, M. & Paganelli, G., Mar 1997, In : Tumori. 83, 2, p. 539-541 3 p.

Research output: Contribution to journalArticle

330 Citations (Scopus)

Overview of results of peptide receptor radionuclide therapy with 3 radiolabeled somatostatin analogs

Kwekkeboom, D. J., Mueller-Brand, J., Paganelli, G., Anthony, L. B., Pauwels, S., Kvols, L. K., O'Dorisio, T. M., Valkema, R., Bodei, L., Chinol, M., Maecke, H. R. & Krenning, E. P., Jan 1 2005, In : Journal of Nuclear Medicine. 46, 1 SUPPL.

Research output: Contribution to journalArticle

Peptide Receptors
Somatostatin
Radioisotopes
Octreotide
Therapeutics
81 Citations (Scopus)

Patient biodistribution of intraperitoneally administered Yttrium-90-labeled antibody

Hnatowich, D. J., Chinol, M., Siebecker, D. A., Gionet, M., Griffin, T., Doherty, P. W., Hunter, R. & Kase, K. R., 1988, In : Journal of Nuclear Medicine. 29, 8, p. 1428-1434 7 p.

Research output: Contribution to journalArticle

Yttrium
Radioactivity
Antibodies
Second-Look Surgery
Neoplasms
195 Citations (Scopus)

Peptide receptor radionuclide therapy with 177Lu-DOTATATE: The IEO phase I-II study

Bodei, L., Cremonesi, M., Grana, C. M., Fazio, N., Iodice, S., Baio, S. M., Bartolomei, M., Lombardo, D., Ferrari, M. E., Sansovini, M., Chinol, M. & Paganelli, G., Dec 2011, In : European Journal of Nuclear Medicine and Molecular Imaging. 38, 12, p. 2125-2135 11 p.

Research output: Contribution to journalArticle

Peptide Receptors
Radioisotopes
Kidney
Bone Marrow
Activity Cycles
3 Citations (Scopus)

Pilot therapy trial of CEA positive tumours using a three-step pretargeting approach

Paganelli, G., Magnani, P., Chinol, M., Sudati, F., Zito, F., Mangili, F., Li, M., Meares, C. F., Siccardi, A. G. & Fazio, F., 1998, In : Tumor Targeting. 3, 2, p. 96-104 9 p.

Research output: Contribution to journalArticle

Avidin
Neoplasms
Biotin
Therapeutics
Bone Marrow
2 Citations (Scopus)

Plasma and synovial fluid concentrations of isoxicam in meniscectomized patients

Ballerini, R., Casini, A., Chinol, M., Mannucci, C., Melani, F. & Ungar, F., 1985, In : Drugs under Experimental and Clinical Research. 11, 8, p. 517-521 5 p.

Research output: Contribution to journalArticle

Synovial Fluid
Capsules
High Pressure Liquid Chromatography
isoxicam
Therapeutics
46 Citations (Scopus)

Poly(ethylene glycol)-avidin bioconjugates: Suitable candidates for tumor pretargeting

Caliceti, P., Chinol, M., Roldo, M., Veronese, F. M., Semenzato, A., Salmaso, S. & Paganelli, G., Sep 18 2002, In : Journal of Controlled Release. 83, 1, p. 97-108 12 p.

Research output: Contribution to journalArticle

Ethylene Glycol
Avidin
Neoplasms
Biotin
Proteins
10 Citations (Scopus)

Preclinical evaluation of 177Lu-Nimotuzumab: A potential tool for radioimmunotherapy of epidermal growth factor receptor-overexpressing tumors

Vera, D. R. B., Eigner, S., Beran, M., Henke, K. E., Laznickova, A., Laznicek, M., Melichar, F. & Chinol, M., Jun 1 2011, In : Cancer Biotherapy and Radiopharmaceuticals. 26, 3, p. 287-297 11 p.

Research output: Contribution to journalArticle

Radioimmunotherapy
Immunoconjugates
Epidermal Growth Factor Receptor
Neoplasms
Pentetic Acid