• 13768 Citations
  • 55 h-Index
1989 …2019
If you made any changes in Pure these will be visible here soon.

Research Output 1989 2019

2011

Ordering a cardiopulmonary exercise test for your patient: Key considerations for the physician

Arena, R., Myers, J., Lavie, C. J., Forman, D. E. & Guazzi, M., Jan 2011, In : Future Cardiology. 7, 1, p. 55-60 6 p.

Research output: Contribution to journalArticle

Exercise Test
Referral and Consultation
Exercise
Physicians
Signs and Symptoms
249 Citations (Scopus)
Systolic Heart Failure
Left Ventricular Function
Stroke Volume
Placebos
Ventilation
20 Citations (Scopus)

Phosphodiesterase-5 inhibition mimics intermittent reoxygenation and improves cardioprotection in the hypoxic myocardium

Milano, G., Bianciardi, P., Rochemont, V., Vassalli, G., von Segesser, L. K., Corno, A. F., Guazzi, M. & Samaja, M., Nov 28 2011, In : PLoS One. 6, 11, e27910.

Research output: Contribution to journalArticle

Type 5 Cyclic Nucleotide Phosphodiesterases
ischemia
myocardium
Myocardium
Ischemia
333 Citations (Scopus)

Pulmonary hypertension in heart failure with preserved ejection fraction: A target of phosphodiesterase-5 inhibition in a 1-year study

Guazzi, M., Vicenzi, M., Arena, R. & Guazzi, M. D., Jul 12 2011, In : Circulation. 124, 2, p. 164-174 11 p.

Research output: Contribution to journalArticle

Type 5 Cyclic Nucleotide Phosphodiesterases
Pulmonary Hypertension
Heart Failure
Lung
Right Ventricular Function
2010
49 Citations (Scopus)

Cardiopulmonary exercise testing: Relevant but underused

Forman, D. E., Myers, J., Lavie, C. J., Guazzi, M., Celli, B. & Arena, R., Nov 2010, In : Postgraduate Medicine. 122, 6, p. 68-86 19 p.

Research output: Contribution to journalArticle

Exercise
Technology
Primary Care Physicians
Cardiology
Dyspnea
21 Citations (Scopus)

Cardiopulmonary exercise testing characteristics in heart failure patients with and without concomitant chronic obstructive pulmonary disease

Guazzi, M., Myers, J., Vicenzi, M., Bensimhon, D., Chase, P., Pinkstaff, S. & Arena, R., Nov 2010, In : American Heart Journal. 160, 5, p. 900-905 6 p.

Research output: Contribution to journalArticle

Chronic Obstructive Pulmonary Disease
Heart Failure
Exercise
Comorbidity
Lung
100 Citations (Scopus)

Cardiopulmonary exercise testing in patients with pulmonary arterial hypertension: An evidence-based review

Arena, R., Lavie, C. J., Milani, R. V., Myers, J. & Guazzi, M., Feb 2010, In : Journal of Heart and Lung Transplantation. 29, 2, p. 159-173 15 p.

Research output: Contribution to journalArticle

Pulmonary Hypertension
Exercise
Carbon Dioxide
Pulmonary Fibrosis
Partial Pressure
34 Citations (Scopus)

Cardiopulmonary exercise testing variables reflect the degree of diastolic dysfunction in patients with heart failure-normal ejection fraction

Guazzi, M., Myers, J., Peberdy, M. A., Bensimhon, D., Chase, P. & Arena, R., May 2010, In : Journal of Cardiopulmonary Rehabilitation and Prevention. 30, 3, p. 165-172 8 p.

Research output: Contribution to journalArticle

Echocardiography
Heart Failure
Exercise
Oxygen
Systolic Heart Failure
826 Citations (Scopus)

Clinician's guide to cardiopulmonary exercise testing in adults: A scientific statement from the American heart association

Balady, G. J., Arena, R., Sietsema, K., Myers, J., Coke, L., Fletcher, G. F., Forman, D., Franklin, B., Guazzi, M., Gulati, M., Keteyian, S. J., Lavie, C. J., MacKo, R., Mancini, D. & Milani, R. V., Jul 13 2010, In : Circulation. 122, 2, p. 191-225 35 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Defining the optimal prognostic window for cardiopulmonary exercise testing in patients with heart failure

Arena, R., Myers, J., Abella, J., Pinkstaff, S., Brubaker, P., Kitzman, D., Peberdy, M. A., Bensimhon, D., Chase, P., Forman, D. E. & Guazzi, M., May 2010, In : Circulation: Heart Failure. 3, 3, p. 405-411 7 p.

Research output: Contribution to journalArticle

Heart-Assist Devices
Oxygen Consumption
Multivariate Analysis
Heart Failure
Exercise
23 Citations (Scopus)

Development of a cardiopulmonary exercise prognostic score for optimizing risk stratification in heart failure: The (P)e(R)i(O)dic (B)reathing during (E)xercise (PROBE) study

Guazzi, M., Boracchi, P., Arena, R., Myers, J., Vicenzi, M., Peberdy, M. A., Bensimhon, D., Chase, P. & Reina, G., Oct 2010, In : Journal of Cardiac Failure. 16, 10, p. 799-805 7 p.

Research output: Contribution to journalArticle

Breathing Exercises
Heart Failure
Exercise
Carbon Dioxide
Oxygen Consumption
15 Citations (Scopus)

Echocardiography with tissue doppler imaging and cardiopulmonary exercise testing in patients with heart failure: A correlative and prognostic analysis

Guazzi, M., Myers, J., Peberdy, M. A., Bensimhon, D., Chase, P., Pinkstaff, S. & Arena, R., Sep 3 2010, In : International Journal of Cardiology. 143, 3, p. 323-329 7 p.

Research output: Contribution to journalArticle

Echocardiography
Heart Failure
Exercise
Stroke Volume
Ventilation
19 Citations (Scopus)

Effect of enalapril on exercise cardiopulmonary performance in chronic obstructive pulmonary disease: A pilot study

Di Marco, F., Guazzi, M., Vicenzi, M., Santus, P., Cazzola, M., Pappalettera, M., Castellotti, P. & Centanni, S., Jun 2010, In : Pulmonary Pharmacology and Therapeutics. 23, 3, p. 159-164 6 p.

Research output: Contribution to journalArticle

Pulmonary diseases
Enalapril
Chronic Obstructive Pulmonary Disease
Peptidyl-Dipeptidase A
Exercise
19 Citations (Scopus)

Effects of treatment strategy on endothelial function

Tomasoni, L., Sitia, S., Borghi, C., Cicero, A. F. G., Ceconi, C., Cecaro, F., Morganti, A., De Gennaro Colonna, V., Guazzi, M., Morricone, L., Malavazos, A. E., Marino, P., Cavallino, C., Shoenfeld, Y. & Turiel, M., Oct 2010, In : Autoimmunity Reviews. 9, 12, p. 840-844 5 p.

Research output: Contribution to journalArticle

Antihypertensive Agents
Atherosclerosis
Oxidoreductases
Cholesterol
Blood Pressure
30 Citations (Scopus)

Exercise intolerance in chronic heart failure: Mechanisms and therapies. Part II

Piepoli, M. F., Guazzi, M., Boriani, G., Cicoira, M., Corrà, U., Libera, L. D., Emdin, M., Mele, D., Passino, C., Vescovo, G., Vigorito, C., Villani, G. & Agostoni, P., Dec 2010, In : European Journal of Cardiovascular Prevention and Rehabilitation. 17, 6, p. 643-648 6 p.

Research output: Contribution to journalArticle

Heart Failure
Exercise
Muscle Fatigue
Cachexia
Dyspnea
88 Citations (Scopus)

Exercise intolerance in chronic heart failure: Mechanisms and therapies. Part i

Piepoli, M. F., Guazzi, M., Boriani, G., Cicoira, M., Corrà, U., Libera, L. D., Emdin, M., Mele, D., Passino, C., Vescovo, G., Vigorito, C., Villani, G. Q. & Agostoni, P., Dec 2010, In : European Journal of Cardiovascular Prevention and Rehabilitation. 17, 6, p. 637-642 6 p.

Research output: Contribution to journalArticle

Heart Failure
Exercise
Muscle Fatigue
Cachexia
Dyspnea
8 Citations (Scopus)

Heart rate recovery and tissue doppler echocardiography in heart failure

Guazzi, M., Myers, J., Peberdy, M., Bensimhon, D., Chase, P., Pinkstaff, S. & Arena, R., Feb 2010, In : Clinical Cardiology. 33, 2

Research output: Contribution to journalArticle

Doppler Echocardiography
Stroke Volume
Echocardiography
Heart Failure
Heart Rate
17 Citations (Scopus)

Heart rate recovery predicts sudden cardiac death in heart failure

Guazzi, M., Myers, J., Peberdy, M. A., Bensimhon, D., Chase, P. & Arena, R., Sep 24 2010, In : International Journal of Cardiology. 144, 1, p. 121-123 3 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Neuromuscular electrical stimulation and inspiratory muscle training as potential adjunctive rehabilitation options for patients with heart failure

Arena, R., Pinkstaff, S., Wheeler, E., Peberdy, M. A., Guazzi, M. & Myers, J., Jul 2010, In : Journal of Cardiopulmonary Rehabilitation and Prevention. 30, 4, p. 209-223 15 p.

Research output: Contribution to journalArticle

Electric Stimulation
Rehabilitation
Heart Failure
Muscles
Exercise
5 Citations (Scopus)

Prognostic characteristics of heart rate recovery according to sex in patients with heart failure

Arena, R., Myers, J., Abella, J., Pinkstaff, S., Peberdy, M. A., Bensimhon, D., Chase, P. & Guazzi, M., Nov 19 2010, In : International Journal of Cardiology. 145, 2, p. 293-294 2 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Prognostic Significance of the Oxygen Uptake Efficiency Slope: Percent-Predicted Versus Actual Value

Arena, R., Myers, J., Abella, J., Pinkstaff, S., Brubaker, P., Kitzman, D., Peberdy, M. A., Bensimhon, D., Chase, P. & Guazzi, M., Mar 1 2010, In : The American Journal of Cardiology. 105, 5, p. 757-758 2 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Prognostic usefulness of the functional aerobic reserve in patients with heart failure

Chase, P., Arena, R., Guazzi, M., Myers, J., Peberdy, M. A. & Bensimhon, D., Nov 2010, In : American Heart Journal. 160, 5, p. 922-927 6 p.

Research output: Contribution to journalArticle

Heart Failure
Oxygen Consumption
Exercise
Systolic Heart Failure
Heart-Assist Devices
89 Citations (Scopus)

Pulmonary hypertension with left-sided heart disease

Guazzi, M. & Arena, R., Nov 2010, In : Nature Reviews Cardiology. 7, 11, p. 648-659 12 p.

Research output: Contribution to journalArticle

Pulmonary Hypertension
Heart Diseases
Mitral Valve Stenosis
Lung Injury
Ventricular Pressure
55 Citations (Scopus)

The future of aerobic exercise testing in clinical practice: Is it the ultimate vital sign?

Arena, R., Myers, J. & Guazzi, M., May 2010, In : Future Cardiology. 6, 3, p. 325-342 18 p.

Research output: Contribution to journalArticle

Vital Signs
Exercise
Respiratory Rate
Body Temperature
Physical Examination
52 Citations (Scopus)

The prognostic value of the heart rate response during exercise and recovery in patients with heart failure: Influence of beta-blockade

Arena, R., Myers, J., Abella, J., Peberdy, M. A., Bensimhon, D., Chase, P. & Guazzi, M., Jan 21 2010, In : International Journal of Cardiology. 138, 2, p. 166-173 8 p.

Research output: Contribution to journalArticle

Heart Failure
Heart Rate
Exercise
Carbon Dioxide
Oxygen Consumption
18 Citations (Scopus)

Ventilatory efficiency and dyspnea on exertion improvements are related to reduced pulmonary pressure in heart failure patients receiving Sildenafil

Guazzi, M., Myers, J., Peberdy, M. A., Bensimhon, D., Chase, P. & Arena, R., Oct 29 2010, In : International Journal of Cardiology. 144, 3, p. 410-412 3 p.

Research output: Contribution to journalArticle

2009
59 Citations (Scopus)

Determining the preferred percent-predicted equation for peak oxygen consumption in patients with heart failure

Arena, R., Myers, J., Abella, J., Pinkstaff, S., Brubaker, P., Moore, B., Kitzman, D., Peberdy, M. A., Bensimhon, D., Chase, P., Forman, D., West, E. & Guazzi, M., Mar 2009, In : Circulation: Heart Failure. 2, 2, p. 113-120 8 p.

Research output: Contribution to journalArticle

Oxygen Consumption
Heart Failure
Exercise
United States Department of Veterans Affairs
Heart-Assist Devices
18 Citations (Scopus)

Does Peak Oxygen Pulse Complement Peak Oxygen Uptake in Risk Stratifying Patients With Heart Failure?

Oliveira, R. B., Myers, J., Araújo, C. G. S., Arena, R., Mandic, S., Bensimhon, D., Abella, J., Chase, P., Guazzi, M., Brubaker, P., Moore, B., Kitzman, D. & Peberdy, M. A., Aug 15 2009, In : The American Journal of Cardiology. 104, 4, p. 554-558 5 p.

Research output: Contribution to journalArticle

Pulse
Heart Failure
Oxygen
Mortality
Exercise
46 Citations (Scopus)

Endothelial dysfunction and pathophysiological correlates in atrial fibrillation

Guazzi, M. & Arena, R., Jan 2009, In : Heart. 95, 2, p. 102-106 5 p.

Research output: Contribution to journalArticle

Atrial Fibrillation
Renin-Angiotensin System
Pulsatile Flow
Nitric Oxide
Nitric Oxide Synthase
3 Citations (Scopus)

Gli inibitori della fosfodiesterasi-5 nella patologia cardiopolmonare: Dai rilievi sperimentali all'applicazione clinica

Translated title of the contribution: Clinical use of phosphodiesterases-5 inhibitors in cardiopulmonary diseases: From experimental evidence to clinical applicationGuazzi, M., Vicenzi, M. & Samaja, M., 2009, In : Giornale Italiano di Cardiologia. 10, 11-12, p. 725-737 13 p.

Research output: Contribution to journalArticle

Type 5 Cyclic Nucleotide Phosphodiesterases
Phosphodiesterase 5 Inhibitors
Myocardial Reperfusion Injury
Cyclic Nucleotides
Phosphoric Diester Hydrolases
28 Citations (Scopus)

Influence of Etiology of Heart Failure on the Obesity Paradox

Arena, R., Myers, J., Abella, J., Pinkstaff, S., Brubaker, P., Moore, B., Kitzman, D., Peberdy, M. A., Bensimhon, D., Chase, P., Forman, D., West, E. & Guazzi, M., Oct 15 2009, In : The American Journal of Cardiology. 104, 8, p. 1116-1121 6 p.

Research output: Contribution to journalArticle

Body Mass Index
Heart Failure
Obesity
Exercise
Carbon Dioxide
4 Citations (Scopus)

Maximal dyspnea on exertion during cardiopulmonary exercise testing is related to poor prognosis and echocardiography with tissue doppler imaging in heart failure

Guazzi, M., Myers, J., Peberdy, M. A., Bensimhon, D., Chase, P. & Arena, R., Nov 2009, In : Congestive Heart Failure. 15, 6, p. 277-283 7 p.

Research output: Contribution to journalArticle

Dyspnea
Echocardiography
Heart Failure
Exercise
Carbon Dioxide
2 Citations (Scopus)

Optimizing the clinical application of cardiopulmonary exercise testing in patients with heart failure

Guazzi, M., Myers, J. & Arena, R., Sep 2009, In : International Journal of Cardiology. 137, 1

Research output: Contribution to journalArticle

Heart Failure
Exercise
Carbon Dioxide
Heart Rate
Clinical Studies
23 Citations (Scopus)

Prognostic value of flow-mediated dilatation following myocardial infarction

Guazzi, M., Reina, G., Gripari, P., Tumminello, G., Vicenzi, M. & Arena, R., Feb 6 2009, In : International Journal of Cardiology. 132, 1, p. 45-50 6 p.

Research output: Contribution to journalArticle

Dilatation
Myocardial Infarction
ROC Curve
Confidence Intervals
Brachial Artery
4 Citations (Scopus)

Regulation of alveolar gas conductance by NO in man, as based on studies with NO donors and inhibitors of NO production

Guazzi, M., Arena, R., Vicenzi, M. & Guazzi, M. D., Jun 2009, In : Acta Physiologica. 196, 2, p. 267-277 11 p.

Research output: Contribution to journalArticle

Nitric Oxide Donors
Nitric Oxide
Gases
Vascular Resistance
Pulmonary Artery
92 Citations (Scopus)

Six-minute walk test and cardiopulmonary exercise testing in patients with chronic heart failure: A comparative analysis on clinical and prognostic insights

Guazzi, M., Dickstein, K., Vicenzi, M. & Arena, R., Nov 2009, In : Circulation: Heart Failure. 2, 6, p. 549-555 7 p.

Research output: Contribution to journalArticle

Heart Failure
Exercise
Breathing Exercises
Anaerobic Threshold
Exercise Test
14 Citations (Scopus)

Six months of Sildenafil therapy improves heart rate recovery in patients with heart failure

Guazzi, M., Arena, R., Pinkstaff, S. & Guazzi, M. D., Aug 21 2009, In : International Journal of Cardiology. 136, 3, p. 341-343 3 p.

Research output: Contribution to journalArticle

Heart Failure
Heart Rate
Vascular Stiffness
Pressoreceptors
Therapeutics
24 Citations (Scopus)
Exercise Test
Heart Failure
Heart Rate
Drug Therapy
Type 5 Cyclic Nucleotide Phosphodiesterases
36 Citations (Scopus)

The Lowest VE/VCO2 Ratio During Exercise as a Predictor of Outcomes in Patients With Heart Failure

Myers, J., Arena, R., Oliveira, R. B., Bensimhon, D., Hsu, L., Chase, P., Guazzi, M., Brubaker, P., Moore, B., Kitzman, D. & Peberdy, M. A., Nov 2009, In : Journal of Cardiac Failure. 15, 9, p. 756-762 7 p.

Research output: Contribution to journalArticle

Ventilation
Heart Failure
Exercise
Weights and Measures
Carbon Dioxide
2008
120 Citations (Scopus)

A cardiopulmonary exercise testing score for predicting outcomes in patients with heart failure

Myers, J., Arena, R., Dewey, F., Bensimhon, D., Abella, J., Hsu, L., Chase, P., Guazzi, M. & Peberdy, M. A., Dec 2008, In : American Heart Journal. 156, 6, p. 1177-1183 7 p.

Research output: Contribution to journalArticle

Heart Failure
Heart Rate
Exercise
Oxygen
Exercise Test
57 Citations (Scopus)

Alveolar Gas Diffusion Abnormalities in Heart Failure

Guazzi, M., Oct 2008, In : Journal of Cardiac Failure. 14, 8, p. 695-702 8 p.

Research output: Contribution to journalArticle

Heart Failure
Gases
Lung
Membranes
Nitric Oxide
35 Citations (Scopus)

Clinical use of phosphodiesterase-5 inhibitors in chronic heart failure.

Guazzi, M., Nov 2008, In : Circulation: Heart Failure. 1, 4, p. 272-280 9 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Endothelium-mediated modulation of ergoreflex and improvement in exercise ventilation by acute sildenafil in heart failure patients

Guazzi, M., Casali, M., Berti, F., Rossoni, G., D'Gennaro Colonna, V. & Guazzi, M. D., Feb 2008, In : Clinical Pharmacology and Therapeutics. 83, 2, p. 336-341 6 p.

Research output: Contribution to journalArticle

Endothelium
Ventilation
Heart Failure
Exercise
Efficiency
9 Citations (Scopus)
Extracellular Fluid
Myocardial Infarction
Lung
Edema
Nitric Oxide
58 Citations (Scopus)

Exercise oscillatory breathing in diastolic heart failure: Prevalence and prognostic insights

Guazzi, M., Myers, J., Peberdy, M. A., Bensimhon, D., Chase, P. & Arena, R., Nov 2008, In : European Heart Journal. 29, 22, p. 2751-2759 9 p.

Research output: Contribution to journalArticle

Diastolic Heart Failure
Breathing Exercises
Systolic Heart Failure
Exercise
Heart Failure
1 Citation (Scopus)

Impaired brachial artery endothelial flow-mediated dilation and orthostatic stress in hemodialysis patients

Gallieni, M., Butti, A., Guazzi, M., Galassi, A., Cozzolino, M. & Brancaccio, D., Jan 2008, In : International Journal of Artificial Organs. 31, 1, p. 34-42 9 p.

Research output: Contribution to journalArticle

Brachial Artery
Renal Dialysis
Dilatation
Supine Position
Chronic Renal Insufficiency
50 Citations (Scopus)

Permanent atrial fibrillation affects exercise capacity in chronic heart failure patients

Agostoni, P., Emdin, M., Corrà, U., Veglia, F., Magrì, D., Tedesco, C. C., Berton, E., Passino, C., Bertella, E., Re, F., Mezzani, A., Belardinelli, R., Colombo, C., La Gioia, R., Vicenzi, M., Giannoni, A., Scrutinio, D., Giannuzzi, P., Tondo, C., Di Lenarda, A. & 3 others, Sinagra, G., Piepoli, M. F. & Guazzi, M., Oct 2008, In : European Heart Journal. 29, 19, p. 2367-2372 6 p.

Research output: Contribution to journalArticle

Anaerobic Threshold
Atrial Fibrillation
Heart Failure
Exercise
Heart Rate
34 Citations (Scopus)

Phosphodiesterase-5 inhibition abolishes neuron apoptosis induced by chronic hypoxia independently of hypoxia-inducible factor-1α signaling

Caretti, A., Bianciardi, P., Ronchi, R., Fantacci, M., Guazzi, M. & Samaja, M., Oct 2008, In : Experimental Biology and Medicine. 233, 10, p. 1222-1230 9 p.

Research output: Contribution to journalArticle

Type 5 Cyclic Nucleotide Phosphodiesterases
Hypoxia-Inducible Factor 1
Neurons
Apoptosis
Nitric Oxide
12 Citations (Scopus)

Prognostic characteristics of cardiopulmonary exercise testing in caucasian and African American patients with heart failure

Arena, R., Myers, J., Abella, J., Peberdy, M. A., Bensimhon, D., Chase, P. & Guazzi, M., Nov 2008, In : Congestive Heart Failure. 14, 6, p. 310-315 6 p.

Research output: Contribution to journalArticle

African Americans
Heart Failure
Exercise
Carbon Dioxide
Oxygen Consumption