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LAV-BPIFB4 associates with reduced frailty in humans and its transfer prevents frailty progression in old mice

Malavolta, M., Dato, S., Villa, F., De Rango, F., Iannone, F., Ferrario, A., Maciag, A., Ciaglia, E., D'amato, A., Carrizzo, A., Basso, A., Orlando, F., Provinciali, M., Madeddu, P., Passarino, G., Vecchione, C., Rose, G. & Puca, A. A., Jan 1 2019, In : Aging. 11, 16, p. 6555-6568 14 p.

Research output: Contribution to journalArticle

Open Access

Nutritional factors modulating alu methylation in an italian sample from the mark-age study including offspring of healthy nonagenarians

Giacconi, R., Malavolta, M., Bürkle, A., Moreno-Villanueva, M., Franceschi, C., Capri, M., Eline Slagboom, P., Jansen, E. H. J. M., Dollé, M. E. T., Grune, T., Weber, D., Hervonen, A., Stuetz, W., Breusing, N., Ciccarone, F., Zampieri, M., Aversano, V., Caiafa, P., Formentini, L., Piacenza, F. & 4 others, Pierpaoli, E., Basso, A., Provinciali, M. & Cardelli, M., Dec 2019, In : Nutrients. 11, 12, 2986.

Research output: Contribution to journalArticle

Open Access

Prevalence and loads of torquetenovirus (TTV) in the European MARK-AGE Study population

Giacconi, R., Maggi, F., Macera, L., Spezia, P. G., Pistello, M., Provinciali, M., Piacenza, F., Basso, A., Bürkle, A., Moreno-Villanueva, M., Dollé, M. E. T., Jansen, E., Grune, T., Stuetz, W., Gonos, E. S., Schön, C., Bernhardt, J., Grubeck-Loebenstein, B., Sikora, E., Dudkowska, M. & 11 others, Janiszewska, D., Toussaint, O., Chainiaux, F. D., Franceschi, C., Capri, M., Hervonen, A., Hurme, M., Slagboom, E., Breusing, N., Mocchegiani, E. & Malavolta, M., Dec 15 2019, In : The journals of gerontology. Series A, Biological sciences and medical sciences.

Research output: Contribution to journalArticle

2018

Allyl isothiocyanate exhibits no anticancer activity in MDA-MB-231 breast cancer cells

Sayeed, M. A., Bracci, M., Ciarapica, V., Malavolta, M., Provinciali, M., Pieragostini, E., Gaetani, S., Monaco, F., Lucarini, G., Rapisarda, V., Di Primio, R. & Santarelli, L., Jan 4 2018, In : International Journal of Molecular Sciences. 19, 1, 145.

Research output: Contribution to journalArticle

Antioxidants linked with physical, cognitive and psychological frailty: Analysis of candidate biomarkers and markers derived from the MARK-AGE study

Rietman, M. L., Spijkerman, A. M. W., Wong, A., van Steeg, H., Bürkle, A., Moreno-Villanueva, M., Sindlinger, T., Franceschi, C., Grubeck-Loebenstein, B., Bernhardt, J., Slagboom, P. E., Toussaint, O., Debacq-Chainiaux, F., Sikora, E., Gonos, E. S., Breusing, N., Stuetz, W., Weber, D., Grune, T., Basso, A. & 6 others, Piacenza, F., Malavolta, M., Collino, S., Jansen, E. H. J. M., Verschuren, W. M. M. & Dollé, M. E. T., Apr 30 2018, In : Mechanisms of Ageing and Development. 177, p. 135-143 9 p.

Research output: Contribution to journalArticle

Measuring zinc in biological nanovesicles by multiple analytical approaches

Piacenza, F., Biesemeier, A., Farina, M., Piva, F., Jin, X., Pavoni, E., Nisi, L., Cardelli, M., Costarelli, L., Giacconi, R., Basso, A., Pierpaoli, E., Provinciali, M., Hwang, J. C. M., Morini, A., di Donato, A. & Malavolta, M., Jul 1 2018, In : Journal of Trace Elements in Medicine and Biology. 48, p. 58-66 9 p.

Research output: Contribution to journalArticle

Torquetenovirus (TTV) load is associated with mortality in Italian elderly subjects

Giacconi, R., Maggi, F., Macera, L., Pistello, M., Provinciali, M., Giannecchini, S., Martelli, F., Spezia, P. G., Mariani, E., Galeazzi, R., Costarelli, L., Iovino, L., Galimberti, S., Nisi, L., Piacenza, F. & Malavolta, M., Oct 2 2018, In : Experimental Gerontology. 112, p. 103-111 9 p.

Research output: Contribution to journalArticle

Torquetenovirus (TTV) load is associated with mortality in Italian elderly subjects

Giacconi, R., Maggi, F., Macera, L., Pistello, M., Provinciali, M., Giannecchini, S., Martelli, F., Spezia, P. G., Mariani, E., Galeazzi, R., Costarelli, L., Iovino, L., Galimberti, S., Nisi, L., Piacenza, F. & Malavolta, M., Oct 2 2018, In : Experimental Gerontology. 112, p. 103-111 9 p.

Research output: Contribution to journalArticle

Zinc supplementation can reduce accumulation of cadmium in aged metallothionein transgenic mice

Pabis, K., Gundacker, C., Giacconi, R., Basso, A., Costarelli, L., Piacenza, F., Strizzi, S., Provinciali, M. & Malavolta, M., Nov 1 2018, In : Chemosphere. 211, p. 855-860 6 p.

Research output: Contribution to journalArticle

2017

DNA hydroxymethylation levels are altered in blood cells from Down syndrome persons enrolled in the MARK-AGE project

Ciccarone, F., Valentini, E., Malavolta, M., Zampieri, M., Bacalini, M. G., Calabrese, R., Guastafierro, T., Reale, A., Franceschi, C., Capri, M., Breusing, N., Grune, T., Moreno-Villanueva, M., Bürkle, A. & Caiafa, P., Oct 21 2017, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences.

Research output: Contribution to journalArticle

Main biomarkers associated with age-related plasma zinc decrease and copper/zinc ratio in healthy elderly from ZincAge study

Giacconi, R., Costarelli, L., Piacenza, F., Basso, A., Rink, L., Mariani, E., Fulop, T., Dedoussis, G., Herbein, G., Provinciali, M., Jajte, J., Lengyel, I., Mocchegiani, E. & Malavolta, M., Dec 2017, In : European Journal of Nutrition. 56, 8, p. 2457-2466 10 p.

Research output: Contribution to journalArticle

Zinc-induced Metallothionein in centenarian offspring from a large European population: the MARK-AGE Project

Giacconi, R., Costarelli, L., Piacenza, F., Basso, A., Bürkle, A., Moreno-Villanueva, M., Grune, T., Weber, D., Stuetz, W., Gonos, E. S., Schön, C., Grubeck-Loebenstein, B., Sikora, E., Toussaint, O., Debacq-Chainiaux, F., Franceschi, C., Hervonen, A., Slagboom, E., Ciccarone, F., Zampieri, M. & 6 others, Caiafa, P., Jansen, E., Dollé, M. E. T., Breusing, N., Mocchegiani, E. & Malavolta, M., Oct 17 2017, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences.

Research output: Contribution to journalArticle

2016

Age-dependent expression of DNMT1 and DNMT3B in PBMCs from a large European population enrolled in the MARK-AGE study

Ciccarone, F., Malavolta, M., Calabrese, R., Guastafierro, T., Bacalini, M. G., Reale, A., Franceschi, C., Capri, M., Hervonen, A., Hurme, M., Grubeck-Loebenstein, B., Koller, B., Bernhardt, J., Schӧn, C., Slagboom, P. E., Toussaint, O., Sikora, E., Gonos, E. S., Breusing, N., Grune, T. & 7 others, Jansen, E. H. J. M., Dollé, M., Moreno-Villanueva, M., Sindlinger, T., Bürkle, A., Zampieri, M. & Caiafa, P., Aug 1 2016, In : Aging Cell. 15, 4, p. 755-765 11 p.

Research output: Contribution to journalArticle

Age-dependent expression of DNMT1 and DNMT3B in PBMCs from a large European population enrolled in the MARK-AGE study

Ciccarone, F., Malavolta, M., Calabrese, R., Guastafierro, T., Bacalini, M. G., Reale, A., Franceschi, C., Capri, M., Hervonen, A., Hurme, M., Grubeck-Loebenstein, B., Koller, B., Bernhardt, J., Schӧn, C., Slagboom, P. E., Toussaint, O., Sikora, E., Gonos, E. S., Breusing, N., Grune, T. & 7 others, Jansen, E., Dollé, M., Moreno-Villanueva, M., Sindlinger, T., Bürkle, A., Zampieri, M. & Caiafa, P., Aug 1 2016, In : Aging Cell. 15, 4, p. 755-765 11 p.

Research output: Contribution to journalArticle

Analysis of the machinery and intermediates of the 5hmC-mediated DNA demethylation pathway in aging on samples from the MARKAGE Study

Valentini, E., Zampieri, M., Malavolta, M., Bacalini, M. G., Calabrese, R., Guastafierro, T., Reale, A., Franceschi, C., Hervonen, A., Koller, B., Bernhardt, J., Eline Slagboom, P., Toussaint, O., Sikora, E., Gonos, E. S., Breusing, N., Grune, T., Jansen, E., Dollé, M. E. T., Moreno-Villanueva, M. & 4 others, Sindlinger, T., Bürkle, A., Ciccarone, F. & Caiafa, P., 2016, In : Aging. 8, 9, p. 1896-1922 27 p.

Research output: Contribution to journalArticle

Analysis of the machinery and intermediates of the 5hmC-mediated DNA demethylation pathway in aging on samples from the MARKAGE Study

Valentini, E., Zampieri, M., Malavolta, M., Bacalini, M. G., Calabrese, R., Guastafierro, T., Reale, A., Franceschi, C., Hervonen, A., Koller, B., Bernhardt, J., Eline Slagboom, P., Toussaint, O., Sikora, E., Gonos, E. S., Breusing, N., Grune, T., Jansen, E., Dollé, M. E. T., Moreno-Villanueva, M. & 4 others, Sindlinger, T., Bürkle, A., Ciccarone, F. & Caiafa, P., 2016, In : Aging. 8, 9, p. 1896-1922 27 p.

Research output: Contribution to journalArticle

Circadian rhythms of body temperature and locomotor activity in aging BALB/c mice: early and late life span predictors

Basso, A., Del Bello, G., Piacenza, F., Giacconi, R., Costarelli, L. & Malavolta, M., Jan 28 2016, (Accepted/In press) In : Biogerontology. p. 1-12 12 p.

Research output: Contribution to journalArticle

Investigation of Fullerene Exposure of Breast Cancer Cells by Time-Gated Scanning Microwave Microscopy

Farina, M., Piacenza, F., De Angelis, F., Mencarelli, D., Morini, A., Venanzoni, G., Pietrangelo, T., Malavolta, M., Basso, A., Provinciali, M., Hwang, J. C. M., Jin, X. & Di Donato, A., 2016, In : IEEE Transactions on Microwave Theory and Techniques.

Research output: Contribution to journalArticle

Main biomarkers associated with age-related plasma zinc decrease and copper/zinc ratio in healthy elderly from ZincAge study

Giacconi, R., Costarelli, L., Piacenza, F., Basso, A., Rink, L., Mariani, E., Fülöp, T., Dedoussis, G., Herbein, G., Provinciali, M., Jajte, J., Lengyel, I., Mocchegiani, E. & Malavolta, M., Jul 26 2016, (Accepted/In press) In : European Journal of Nutrition. p. 1-10 10 p.

Research output: Contribution to journalArticle

Therapeutic modulators of cellular senescence: Common targets in cancer and aging

Provinciali, M. & Malavolta, M., Mar 1 2016, In : Current Drug Targets. 17, 4, p. 376 1 p.

Research output: Contribution to journalArticle

Effect of 6-month caloric restriction on Cu bound to ceruloplasmin in adult overweight subjects

Piacenza, F., Malavolta, M., Basso, A., Costarelli, L., Giacconi, R., Ravussin, E., Redman, L. M. & Mocchegiani, E., Aug 1 2015, In : Journal of Nutritional Biochemistry. 26, 8, p. 876-882 7 p.

Research output: Contribution to journalArticle

Effect of ZIP2 Gln/Arg/Leu (rs2234632) polymorphism on zinc homeostasis and inflammatory response following zinc supplementation

Giacconi, R., Costarelli, L., Malavolta, M., Cardelli, M., Galeazzi, R., Piacenza, F., Gasparini, N., Basso, A., Mariani, E., Fulop, T., Rink, L., Dedoussis, G., Herbein, G., Jajte, J., Provinciali, M., Busco, F. & Mocchegiani, E., Nov 1 2015, In : BioFactors. 41, 6, p. 414-423 10 p.

Research output: Contribution to journalArticle

Serum copper to zinc ratio: Relationship with aging and health status

Malavolta, M., Piacenza, F., Basso, A., Giacconi, R., Costarelli, L. & Mocchegiani, E., Nov 1 2015, In : Mechanisms of Ageing and Development. 151, p. 93-100 8 p.

Research output: Contribution to journalArticle

2014

Association among 1267 A/G HSP70-2, -308 G/A TNF-α polymorphisms and pro-inflammatory plasma mediators in old ZincAge population

Giacconi, R., Costarelli, L., Malavolta, M., Piacenza, F., Galeazzi, R., Gasparini, N., Basso, A., Mariani, E., Fulop, T., Rink, L., Dedoussis, G., Kanoni, S., Herbein, G., Jajte, J., Busco, F. & Mocchegiani, E., Feb 2014, In : Biogerontology. 15, 1, p. 65-79 15 p.

Research output: Contribution to journalArticle

Effects of zinc-fortified drinking skim milk (as functional food) on cytokine release and thymic hormone activity in very old persons: A pilot study

Costarelli, L., Giacconi, R., Malavolta, M., Basso, A., Piacenza, F., DeMartiis, M., Giannandrea, E., Renieri, C., Busco, F., Galeazzi, R. & Mocchegiani, E., 2014, In : Age. 36, 3, p. 1421-1431 11 p.

Research output: Contribution to journalArticle

Effects of zinc-fortified drinking skim milk (as functional food) on cytokine release and thymic hormone activity in very old persons: a pilot study

Costarelli, L., Giacconi, R., Malavolta, M., Basso, A., Piacenza, F., DeMartiis, M. L., Giannandrea, E., Renieri, C., Busco, F., Galeazzi, R. & Mocchegiani, E., Jun 1 2014, In : Age. 36, 3, p. 9656 1 p.

Research output: Contribution to journalArticle

Il modello del siero postprandiale, un "tool" trascurato per le sperimentazioni in vitro di nutrienti

Translated title of the contribution: The postprandial serum: A neglected "tool" for nutritional studiesPiacenza, F., Malavolta, M., Costarelli, L., Giacconi, R., Basso, A. & Mocchegiani, E., Dec 1 2014, In : Progress in Nutrition. 16, 4, p. 276-283 8 p.

Research output: Contribution to journalArticle

Influence of +1245 A/G MT1A polymorphism on advanced glycation end-products (AGEs) in elderly: effect of zinc supplementation

Giacconi, R., Simm, A., Santos, A. N., Costarelli, L., Malavolta, M., Mecocci, P., Piacenza, F., Basso, A., Fulop, T., Rink, L., Dedoussis, G., Kanoni, S., Herbein, G., Jajte, J. & Mocchegiani, E., 2014, In : Genes and Nutrition. 9, 5

Research output: Contribution to journalArticle

Micronutrient-gene interactions related to inflammatory/immune response and antioxidant activity in ageing and inflammation. A systematic review

Mocchegiani, E., Costarelli, L., Giacconi, R., Malavolta, M., Basso, A., Piacenza, F., Ostan, R., Cevenini, E., Gonos, E. S. & Monti, D., 2014, In : Mechanisms of Ageing and Development. 136-137, p. 29-49 21 p.

Research output: Contribution to journalArticle

Vitamin E-gene interactions in aging and inflammatory age-related diseases: Implications for treatment. A systematic review

Mocchegiani, E., Costarelli, L., Giacconi, R., Malavolta, M., Basso, A., Piacenza, F., Ostan, R., Cevenini, E., Gonos, E. S., Franceschi, C. & Monti, D., 2014, In : Ageing Research Reviews. 14, 1, p. 81-101 21 p.

Research output: Contribution to journalArticle

2013

Effects of human Toll-like receptor 1 polymorphisms on ageing

Uciechowski, P., Oellig, E. M., Mariani, E., Malavolta, M., Mocchegiani, E. & Rink, L., Feb 7 2013, In : Immunity and Ageing. 10, 1, 4.

Research output: Contribution to journalArticle

Metallothioneins, ageing and cellular senescence: A future therapeutic target

Mocchegiani, E., Costarelli, L., Basso, A., Giacconi, R., Piacenza, F. & Malavolta, M., 2013, In : Current Pharmaceutical Design. 19, 9, p. 1753-1764 12 p.

Research output: Contribution to journalArticle