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Research Output 1981 2019

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2019

Characterisation of a β detector on positron emitters for medical applications

Collamati, F., Moretti, R., Alunni-Solestizi, L., Bocci, V., Cartoni, A., Collarino, A., De Simoni, M., Faccini, R., Fischetti, M., Giordano, A., Maccora, D., Mancini-Terracciano, C., Mirabelli, R., Scotognella, T., Solfaroli-Camillocci, E., Traini, G. & Morganti, S., Nov 2019, In : Physica Medica. 67, p. 85-90 6 p.

Research output: Contribution to journalArticle

Radio
surgery
positrons
emitters
Electrons
Interleukin-9
Interleukin-13
Interleukin-5
Interleukin-4
Brain Injuries

Dexamethasone Conjugation to Biodegradable Avidin-Nucleic-Acid-Nano-Assemblies Promotes Selective Liver Targeting and Improves Therapeutic Efficacy in an Autoimmune Hepatitis Murine Model

Violatto, M. B., Casarin, E., Talamini, L., Russo, L., Baldan, S., Tondello, C., Messmer, M., Hintermann, E., Rossi, A., Passoni, A., Bagnati, R., Biffi, S., Toffanin, C., Gimondi, S., Fumagalli, S., De Simoni, M. G., Barisani, D., Salmona, M., Christen, U., Invernizzi, P. & 2 others, Bigini, P. & Morpurgo, M., Apr 23 2019, In : ACS Nano. 13, 4, p. 4410-4423 14 p.

Research output: Contribution to journalArticle

hepatitis
Avidin
Nucleic acids
nucleic acids
conjugation

Human brain trauma severity is associated with lectin complement pathway activation

De Blasio, D., Fumagalli, S., Orsini, F., Neglia, L., Perego, C., Ortolano, F., Zanier, E. R., Picetti, E., Locatelli, M., Stocchetti, N., Longhi, L., Garred, P. & De Simoni, M. G., 2019, In : Journal of Cerebral Blood Flow and Metabolism. 39, 5, p. 794-807

Research output: Contribution to journalArticle

Mannose-Binding Lectin Complement Pathway
Complement Activation
Mannose-Binding Protein-Associated Serine Proteases
Brain Injuries
Lectins

Human brain trauma severity is associated with lectin complement pathway activation

De Blasio, D., Fumagalli, S., Orsini, F., Neglia, L., Perego, C., Ortolano, F., Zanier, E. R., Picetti, E., Locatelli, M., Stocchetti, N., Longhi, L., Garred, P. & De Simoni, M-G., May 2019, In : Journal of Cerebral Blood Flow and Metabolism. 39, 5, p. 794-807 14 p.

Research output: Contribution to journalArticle

Mannose-Binding Lectin Complement Pathway
Complement Activation
Mannose-Binding Protein-Associated Serine Proteases
Brain Injuries
Lectins

Mannose-binding lectin has a direct deleterious effect on ischemic brain microvascular endothelial cells

Neglia, L., Fumagalli, S., Orsini, F., Zanetti, A., Perego, C. & De Simoni, M-G., Sep 7 2019, In : Journal of Cerebral Blood Flow and Metabolism. p. 271678X19874509

Research output: Contribution to journalArticle

Mannose-Binding Lectin
Endothelial Cells
Brain
Oxygen
Glucose

SELENON (SEPN1) protects skeletal muscle from saturated fatty acid-induced ER stress and insulin resistance

Varone, E., Pozzer, D., Di Modica, S., Chernorudskiy, A., Nogara, L., Baraldo, M., Cinquanta, M., Fumagalli, S., Villar-Quiles, R. N., De Simoni, M-G., Blaauw, B., Ferreiro, A. & Zito, E., Jun 2019, In : Redox Biology. 24, p. 101176

Research output: Contribution to journalArticle

Selenoproteins
Endoplasmic Reticulum Stress
Muscle
Insulin Resistance
Skeletal Muscle

Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury

Neglia, L., Oggioni, M., Mercurio, D., De Simoni, M-G. & Fumagalli, S., Apr 9 2019, In : Cellular and Molecular Immunology.

Research output: Contribution to journalArticle

Mannose-Binding Lectin
Reperfusion Injury
Brain Ischemia
Protein Isoforms
Middle Cerebral Artery Infarction
Myeloid Cells
Lighting
Microscopy
Ischemia
Brain
2018

Induction of a transmissible tau pathology by traumatic brain injury

Zanier, E. R., Bertani, I., Sammali, E., Pischiutta, F., Chiaravalloti, M. A., Vegliante, G., Masone, A., Corbelli, A., Smith, D. H., Menon, D. K., Stocchetti, N., Fiordaliso, F., De Simoni, M-G., Stewart, W. & Chiesa, R., Sep 1 2018, In : Brain. 141, 9, p. 2685-2699 15 p.

Research output: Contribution to journalArticle

Induction of a transmissible tau pathology by traumatic brain injury

Zanier, E. R., Bertani, I., Sammali, E., Pischiutta, F., Chiaravalloti, M. A., Vegliante, G., Masone, A., Corbelli, A., Smith, D. H., Menon, D. K., Stocchetti, N., Fiordaliso, F., De Simoni, M-G., Stewart, W. & Chiesa, R., Sep 1 2018, In : Brain : a journal of neurology. 141, 9, p. 2685-2699 15 p.

Research output: Contribution to journalArticle

Pathology
Tauopathies
Memory Disorders
Wounds and Injuries
Neurodegenerative Diseases

Mannose-Binding Lectin Drives Platelet Inflammatory Phenotype and Vascular Damage After Cerebral Ischemia in Mice via IL (Interleukin)-1α

Orsini, F., Fumagalli, S., Császár, E., Tóth, K., De Blasio, D., Zangari, R., Lénárt, N., Dénes, Á. & De Simoni, M-G., Nov 2018, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 38, 11, p. 2678-2690 13 p.

Research output: Contribution to journalArticle

Mannose-Binding Lectin
Brain Ischemia
Interleukin-1
Blood Vessels
Blood Platelets

Single severe traumatic brain injury produces progressive pathology with ongoing contralateral white matter damage one year after injury

Pischiutta, F., Micotti, E., Hay, J. R., Marongiu, I., Sammali, E., Tolomeo, D., Vegliante, G., Stocchetti, N., Forloni, G., De Simoni, M. G., Stewart, W. & Zanier, E. R., Feb 1 2018, In : Experimental Neurology. 300, p. 167-178 12 p.

Research output: Contribution to journalArticle

Pathology
Wounds and Injuries
Anisotropy
Corpus Striatum
Functional Neuroimaging

Single severe traumatic brain injury produces progressive pathology with ongoing contralateral white matter damage one year after injury

Pischiutta, F., Micotti, E., Hay, J. R., Marongiu, I., Sammali, E., Tolomeo, D., Vegliante, G., Stocchetti, N., Forloni, G., De Simoni, M. G., Stewart, W. & Zanier, E. R., Feb 1 2018, In : Experimental Neurology. 300, p. 167-178 12 p.

Research output: Contribution to journalArticle

2017

C-reactive protein binds to cholesterol crystals and co-localizes with the terminal complement complex in human atherosclerotic plaques

Pilely, K., Fumagalli, S., Rosbjerg, A., Genster, N., Skjoedt, M. O., Perego, C., Ferrante, A. M. R., De Simoni, M. G. & Garred, P., Aug 29 2017, In : Frontiers in Immunology. 8, AUG, p. 1040

Research output: Contribution to journalArticle

Complement Membrane Attack Complex
Atherosclerotic Plaques
C-Reactive Protein
Serum Amyloid P-Component
Cholesterol

Intravenous infusion of human bone marrow mesenchymal stromal cells promotes functional recovery and neuroplasticity after ischemic stroke in mice

Sammali, E., Alia, C., Vegliante, G., Colombo, V., Giordano, N., Pischiutta, F., Boncoraglio, G. B., Barilani, M., Lazzari, L., Caleo, M., De Simoni, M. G., Gaipa, G., Citerio, G. & Zanier, E. R., Dec 1 2017, In : Scientific Reports. 7, 1, 6962.

Research output: Contribution to journalArticle

Neuronal Plasticity
Mesenchymal Stromal Cells
Intravenous Infusions
Stroke
Middle Cerebral Artery Infarction

Intravenous infusion of human bone marrow mesenchymal stromal cells promotes functional recovery and neuroplasticity after ischemic stroke in mice

Sammali, E., Alia, C., Vegliante, G., Colombo, V., Giordano, N., Pischiutta, F., Boncoraglio, G. B., Barilani, M., Lazzari, L., Caleo, M., De Simoni, M-G., Gaipa, G., Citerio, G. & Zanier, E. R., Jul 31 2017, In : Scientific Reports. 7, 1, p. 6962

Research output: Contribution to journalArticle

Neuronal Plasticity
Mesenchymal Stromal Cells
Intravenous Infusions
Stroke
Middle Cerebral Artery Infarction

Lectin Pathway of Complement Activation Is Associated with Vulnerability of Atherosclerotic Plaques

Fumagalli, S., Perego, C., Zangari, R., De Blasio, D., Oggioni, M., De Nigris, F., Snider, F., Garred, P., Ferrante, A. M. R. & De Simoni, M-G., 2017, In : Frontiers in Immunology. 8, p. 288

Research output: Contribution to journalArticle

Complement Activation
Atherosclerotic Plaques
Lectins
Tunica Media
Mannose-Binding Lectin

Pharmacological inhibition of mannose-binding lectin ameliorates neurobehavioral dysfunction following experimental traumatic brain injury

De Blasio, D., Fumagalli, S., Longhi, L., Orsini, F., Palmioli, A., Stravalaci, M., Vegliante, G., Zanier, E. R., Bernardi, A., Gobbi, M. & De Simoni, M. G., Mar 1 2017, In : Journal of Cerebral Blood Flow and Metabolism. 37, 3, p. 938-950 13 p.

Research output: Contribution to journalArticle

Targeting extracellular cyclophilin a reduces neuroinflammation and extends survival in a mouse model of amyotrophic lateral sclerosis

Pasetto, L., Pozzi, S., Castelnovo, M., Basso, M., Estevez, A. G., Fumagalli, S., De Simoni, M. G., Castellaneta, V., Bigini, P., Restelli, E., Chiesa, R., Trojsi, F., Monsurrò, M. R., Callea, L., Malešević, M., Fischer, G., Freschi, M., Tortarolo, M., Bendotti, C. & Bonetto, V., Feb 8 2017, In : Journal of Neuroscience. 37, 6, p. 1413-1427 15 p.

Research output: Contribution to journalArticle

Targeting extracellular cyclophilin a reduces neuroinflammation and extends survival in a mouse model of amyotrophic lateral sclerosis

Pasetto, L., Pozzi, S., Castelnovo, M., Basso, M., Estevez, A. G., Fumagalli, S., De Simoni, M. G., Castellaneta, V., Bigini, P., Restelli, E., Chiesa, R., Trojsi, F., Monsurrò, M. R., Callea, L., Malešević, M., Fischer, G., Freschi, M., Tortarolo, M., Bendotti, C. & Bonetto, V., Feb 8 2017, In : Journal of Neuroscience. 37, 6, p. 1413-1427 15 p.

Research output: Contribution to journalArticle

cis-trans-Isomerases
Cyclophilins
Peptidylprolyl Isomerase
Amyotrophic Lateral Sclerosis
Sclerosis
2016

A New Surface Plasmon Resonance Assay for in Vitro Screening of Mannose-Binding Lectin Inhibitors

Stravalaci, M., De Blasio, D., Orsini, F., Perego, C., Palmioli, A., Goti, G., Bernardi, A., De Simoni, M. G. & Gobbi, M., Aug 1 2016, In : Journal of Biomolecular Screening. 21, 7, p. 749-757 9 p.

Research output: Contribution to journalArticle

Mannose-Binding Lectin
Surface Plasmon Resonance
Surface plasmon resonance
Assays
Screening

Differential transgene expression patterns in Alzheimer mouse models revealed by novel human amyloid precursor protein-specific antibodies

Höfling, C., Morawski, M., Zeitschel, U., Zanier, E. R., Moschke, K., Serdaroglu, A., Canneva, F., von Hörsten, S., De Simoni, M. G., Forloni, G., Jäger, C., Kremmer, E., Roßner, S., Lichtenthaler, S. F. & Kuhn, P. H., Oct 1 2016, In : Aging Cell. 15, 5, p. 953-963 11 p.

Research output: Contribution to journalArticle

Amyloid beta-Protein Precursor
Transgenes
Antibodies
Genetically Modified Animals
Brain

Early ficolin-1 is a sensitive prognostic marker for functional outcome in ischemic stroke

Zangari, R., Roncati Zanier, E., Torgano, G. G., Bersano, A., Beretta, S., Beghi, E., Casolla, B., Checcarelli, N., Lanfranconi, S., Maino, A., Mandelli, C., Micieli, G., Orzi, F., Picetti, E., Silvestrini, M., Stocchetti, N., Zecca, B., Garred, P. & De Simoni, M. G., Jan 20 2016, (Accepted/In press) In : Journal of Neuroinflammation.

Research output: Contribution to journalArticle

Mannose-Binding Lectin Complement Pathway
Stroke
Mannose-Binding Lectin
National Institutes of Health (U.S.)
Multicenter Studies

Early ficolin-1 is a sensitive prognostic marker for functional outcome in ischemic stroke

Zangari, R., Roncati Zanier, E., Torgano, G. G., Bersano, A., Beretta, S., Beghi, E., Casolla, B., Checcarelli, N., Lanfranconi, S., Maino, A., Mandelli, C., Micieli, G., Orzi, F., Picetti, E., Silvestrini, M., Stocchetti, N., Zecca, B., Garred, P. & De Simoni, M. G., Jan 20 2016, (Accepted/In press) In : Journal of Neuroinflammation.

Research output: Contribution to journalArticle

Mannose-Binding Lectin Complement Pathway
Stroke
Mannose-Binding Lectin
National Institutes of Health (U.S.)
Multicenter Studies

Early ficolin-1 is a sensitive prognostic marker for functional outcome in ischemic stroke

Zangari, R., Roncati Zanier, E., Torgano, G. G., Bersano, A., Beretta, S., Beghi, E., Casolla, B., Checcarelli, N., Lanfranconi, S., Maino, A., Mandelli, C., Micieli, G., Orzi, F., Picetti, E., Silvestrini, M., Stocchetti, N., Zecca, B., Garred, P. & De Simoni, M. G., 2016, In : Journal of Neuroinflammation. 13, 1, 16.

Research output: Contribution to journalArticle

Mannose-Binding Lectin Complement Pathway
Stroke
Mannose-Binding Lectin
National Institutes of Health (U.S.)
Multicenter Studies

Early ficolin-1 is a sensitive prognostic marker for functional outcome in ischemic stroke

Zangari, R., Zanier, E. R., Torgano, G., Bersano, A., Beretta, S., Beghi, E., Casolla, B., Checcarelli, N., Lanfranconi, S., Maino, A., Mandelli, C., Micieli, G., Orzi, F., Picetti, E., Silvestrini, M., Stocchetti, N., Zecca, B., Garred, P. & De Simoni, M. G., 2016, In : Journal of Neuroinflammation. 13, p. 16

Research output: Contribution to journalArticle

Mannose-Binding Lectin Complement Pathway
Stroke
Mannose-Binding Lectin
National Institutes of Health (U.S.)
Multicenter Studies

Fractalkine receptor deficiency is associated with early protection but late worsening of outcome following brain trauma in mice

Roncati Zanier, E., Marchesi, F., Ortolano, F., Perego, C., Arabian, M., Zoerle, T., Sammali, E., Pischiutta, F. & De Simoni, M. G., Jun 1 2016, In : Journal of Neurotrauma. 33, 11, p. 1060-1072 13 p.

Research output: Contribution to journalArticle

Microglia
Nitric Oxide Synthase Type II
Somatomedins
Myeloid Cells
Brain Injuries

Fractalkine receptor deficiency is associated with early protection but late worsening of outcome following brain trauma in mice

Roncati Zanier, E., Marchesi, F., Ortolano, F., Perego, C., Arabian, M., Zoerle, T., Sammali, E., Pischiutta, F. & De Simoni, M. G., Jun 1 2016, In : Journal of Neurotrauma. 33, 11, p. 1060-1072 13 p.

Research output: Contribution to journalArticle

Microglia
Nitric Oxide Synthase Type II
Somatomedins
Myeloid Cells
Brain Injuries

Fractalkine receptor deficiency is associated with early protection but late worsening of outcome following brain trauma in mice

Zanier, E. R., Marchesi, F., Ortolano, F., Perego, C., Arabian, M., Zoerle, T., Sammali, E., Pischiutta, F. & De Simoni, M. G., Jun 1 2016, In : Journal of Neurotrauma. 33, 11, p. 1060-1072 13 p.

Research output: Contribution to journalArticle

Microglia
Nitric Oxide Synthase Type II
Somatomedins
Myeloid Cells
Brain Injuries

Internalization of nanopolymeric tracers does not alter characteristics of placental cells

Bigini, P., Roncati Zanier, E., Saragozza, S., Maciotta, S., Romele, P., Bonassi Signoroni, P., Silini, A., Pischiutta, F., Sammali, E., Balducci, C., Violatto, M. B., Talamini, L., Garry, D., Moscatelli, D., Ferrari, R., Salmona, M., De Simoni, M. G., Maggi, F., Simoni, G., Grati, F. R. & 1 others, Parolini, O., 2016, (Accepted/In press) In : Journal of Cellular and Molecular Medicine.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Middle Cerebral Artery Infarction
Cell- and Tissue-Based Therapy
Chorionic Villi
Amnion

Internalization of nanopolymeric tracers does not alter characteristics of placental cells

Bigini, P., Zanier, E. R., Saragozza, S., Maciotta, S., Romele, P., Bonassi Signoroni, P., Silini, A., Pischiutta, F., Sammali, E., Balducci, C., Violatto, M. B., Talamini, L., Garry, D., Moscatelli, D., Ferrari, R., Salmona, M., De Simoni, M. G., Maggi, F., Simoni, G., Grati, F. R. & 1 others, Parolini, O., 2016, In : Journal of Cellular and Molecular Medicine. 20, p. 1036-1048

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Middle Cerebral Artery Infarction
Cell- and Tissue-Based Therapy
Chorionic Villi
Amnion

Lectin Complement Pathway and Its Bloody Interactions in Brain Ischemia

Fumagalli, S. & De Simoni, M. G., Dec 1 2016, In : Stroke. 47, 12, p. 3067-3073 7 p.

Research output: Contribution to journalArticle

Macrophages are essential for maintaining a M2 protective response early after ischemic brain injury

Perego, C., Fumagalli, S., Zanier, E. R., Carlino, E., Panini, N., Erba, E. & De Simoni, M. G., Dec 1 2016, In : Neurobiology of Disease. 96, p. 284-293 10 p.

Research output: Contribution to journalArticle

Brain Injuries
Macrophages
Monocytes
Microglia
Diphtheria Toxin

Mannan binding lectin-associated serine protease-2 (MASP-2) critically contributes to post-ischemic brain injury independent of MASP-1

Orsini, F., Chrysanthou, E., Dudler, T., Cummings, W. J., Takahashi, M., Fujita, T., Demopulos, G., De Simoni, M. G. & Schwaeble, W., Aug 30 2016, In : Journal of Neuroinflammation. 13, 1, 213.

Research output: Contribution to journalArticle

Mannose-Binding Protein-Associated Serine Proteases
Brain Injuries
Brain Ischemia
Lectins
Microglia

Protection of Brain Injury by Amniotic Mesenchymal Stromal Cell-Secreted Metabolites

Pischiutta, F., Brunelli, L., Romele, P., Silini, A., Sammali, E., Paracchini, L., Marchini, S., Talamini, L., Bigini, P., Boncoraglio, G. B., Pastorelli, R., de Simoni, M. G., Parolini, O. & Zanier, E. R., 2016, In : Critical Care Medicine.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Brain Injuries
Conditioned Culture Medium
Brain
RNA

Protection of Brain Injury by Amniotic Mesenchymal Stromal Cell-Secreted Metabolites

Pischiutta, F., Brunelli, L., Romele, P., Silini, A., Sammali, E., Paracchini, L., Marchini, S., Talamini, L., Bigini, P., Boncoraglio, G. B., Pastorelli, R., De Simoni, M. G., Parolini, O. & Roncati Zanier, E., 2016, In : Critical Care Medicine. 44, p. e1118-e1131

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Brain Injuries
Conditioned Culture Medium
Brain
RNA

Scaffold Optimisation of Tetravalent Antagonists of the Mannose Binding Lectin

Goti, G., Palmioli, A., Stravalaci, M., Sattin, S., De Simoni, M. G., Gobbi, M. & Bernardi, A., Mar 7 2016, In : Chemistry - A European Journal. 22, 11, p. 3686-3691 6 p.

Research output: Contribution to journalArticle

Mannose-Binding Lectin
Scaffolds
Dendrimers
Polyesters
Glycoconjugates
2015

Critical role and therapeutic control of the lectin pathway of complement activation in an abortion-prone mouse mating

Petitbarat, M., Durigutto, P., Macor, P., Bulla, R., Palmioli, A., Bernardi, A., De Simoni, M. G., Ledee, N., Chaouat, G. & Tedesco, F., Dec 15 2015, In : Journal of Immunology. 195, 12, p. 5602-5607 6 p.

Research output: Contribution to journalArticle

Inbred CBA Mouse
Complement Activation
Lectins
Pregnancy
Spontaneous Abortion

Direct reprogramming of human bone marrow stromal cells into functional renal cells using cell-free extracts

Papadimou, E., Morigi, M., Iatropoulos, P., Xinaris, C., Tomasoni, S., Benedetti, V., Longaretti, L., Rota, C., Todeschini, M., Rizzo, P., Introna, M., De Simoni, M. G., Remuzzi, G., Goligorsky, M. S. & Benigni, A., 2015, In : Stem Cell Reports. 4, 4, p. 685-698 14 p.

Research output: Contribution to journalArticle

Cell Extracts
Mesenchymal Stromal Cells
Bone
Kidney
Cadherins

Results of a preclinical randomized controlled multicenter trial (pRCT): Anti-CD49d treatment for acute brain ischemia

Llovera, G., Hofmann, K., Roth, S., Salas-Pérdomo, A., Ferrer-Ferrer, M., Perego, C., Zanier, E. R., Mamrak, U., Rex, A., Party, H., Agin, V., Fauchon, C., Orset, C., Haelewyn, B., De Simoni, M. G., Dirnagl, U., Grittner, U., Planas, A. M., Plesnila, N., Vivien, D. & 1 others, Liesz, A., Aug 5 2015, In : Science Translational Medicine. 7, 299, 299ra121.

Research output: Contribution to journalArticle

Brain Ischemia
Multicenter Studies
Leukocytes
Randomized Controlled Trials
Middle Cerebral Artery Infarction

The ischemic environment drive s microglia and macrophage function

Fumagalli, S., Perego, C., Pischiutta, F., Zanier, E. R. & De Simoni, M. G., 2015, In : Frontiers in Neurology. 6, MAR, 81.

Research output: Contribution to journalArticle

Microglia
Macrophages
Myeloid Cells
Brain Injuries
Homeostasis
2014

A close look at brain dynamics: Cells and vessels seen by in vivo two-photon microscopy

Fumagalli, S., Ortolano, F. & De Simoni, M. G., Oct 1 2014, In : Progress in Neurobiology. 121, p. 36-54 19 p.

Research output: Contribution to journalArticle

Photons
Microscopy
Brain
Blood Vessels
Post and Core Technique

An integrated approach for the systematic evaluation of polymeric nanoparticles in healthy and diseased organisms

Sitia, L., Paolella, K., Romano, M., Violatto, M. B., Ferrari, R., Fumagalli, S., Colombo, L., Bello, E., De Simoni, M. G., D'Incalci, M., Morbidelli, M., Erba, E., Salmona, M., Moscatelli, D. & Bigini, P., 2014, In : Journal of Nanoparticle Research. 16, 7, 2481.

Research output: Contribution to journalArticle

organisms
Nanoparticles
nanoparticles
evaluation
Evaluation

Bone Marrow Mesenchymal Stromal Cells Drive Protective M2 Microglia Polarization After Brain Trauma

Zanier, E. R., Pischiutta, F., Riganti, L., Marchesi, F., Turola, E., Fumagalli, S., Perego, C., Parotto, E., Vinci, P., Veglianese, P., D'Amico, G., Verderio, C. & De Simoni, M. G., 2014, In : Neurotherapeutics. 11, 3, p. 679-695 17 p.

Research output: Contribution to journalArticle

Microglia
Mesenchymal Stromal Cells
Phagocytosis
Tumor Necrosis Factor-alpha
Phenotype

Ficolin-3-mediated lectin complement pathway activation in patients with subarachnoid hemorrhage

Zanier, E. R., Zangari, R., Munthe-Fog, L., Hein, E., Zoerle, T., Conte, V., Orsini, F., Tettamanti, M., Stocchetti, N., Garred, P. & De Simoni, M. G., Jan 14 2014, In : Neurology. 82, 2, p. 126-134 9 p.

Research output: Contribution to journalArticle

Mannose-Binding Lectin Complement Pathway
Complement Activation
Subarachnoid Hemorrhage
Brain Ischemia
ficolin

Immunosuppression does not affect human bone marrow mesenchymal stromal cell efficacy after transplantation in traumatized mice brain

Pischiutta, F., D'Amico, G., Dander, E., Biondi, A., Biagi, E., Citerio, G., De Simoni, M. G. & Zanier, E. R., Apr 2014, In : Neuropharmacology. 79, p. 119-126 8 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Immunosuppression
Transplantation
Brain
Cyclosporine

Mannose-binding lectin is expressed after clinical and experimental traumatic brain injury and its deletion is protective

Longhi, L., Orsini, F., De Blasio, D., Fumagalli, S., Ortolano, F., Locatelli, M., Stocchetti, N. & De Simoni, M. G., 2014, In : Critical Care Medicine. 42, 8, p. 1910-1918 9 p.

Research output: Contribution to journalArticle

Mannose-Binding Lectin
Traumatic Brain Injury
Knockout Mice
Mannose-Binding Lectin Complement Pathway

Versatility of the complement system in neuroinflammation, neurodegeneration and brain homeostasis

Orsini, F., De Blasio, D., Zangari, R., Zanier, E. R. & De Simoni, M. G., Nov 7 2014, In : Frontiers in Cellular Neuroscience. 8, November

Research output: Contribution to journalArticle

Homeostasis
Complement Activation
Brain
Brain Injuries
Complement System Proteins
2013

Changes of the GPR17 receptor, a new target for neurorepair, in neurons and glial cells in patients with traumatic brain injury

Franke, H., Parravicini, C., Lecca, D., Zanier, E. R., Heine, C., Bremicker, K., Fumagalli, M., Rosa, P., Longhi, L., Stocchetti, N., De Simoni, M. G., Weber, M. & Abbracchio, M. P., Sep 2013, In : Purinergic Signalling. 9, 3, p. 451-462 12 p.

Research output: Contribution to journalArticle

Neuroglia
Contusions
Neurons
Oligodendroglia
Neurosurgery