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  • 19 h-Index
1989 …2015
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Research Output 1989 2015

  • 2022 Citations
  • 19 h-Index
  • 40 Article
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Article
2015
3 Citations (Scopus)

Epigenomics of Neural Cells: REST-Induced Down- and Upregulation of Gene Expression in a Two-Clone PC12 Cell Model

Garcia-Manteiga, J. M., Bonfiglio, S., Malosio, M. L., Lazarevic, D., Stupka, E., Cittaro, D. & Meldolesi, J., 2015, In : BioMed Research International. 2015, 202914.

Research output: Contribution to journalArticle

Clone cells
PC12 Cells
Epigenomics
Gene expression
Up-Regulation
18 Citations (Scopus)
Autologous Transplantation
Islets of Langerhans
Iron
Magnetic resonance
Grafts
4 Citations (Scopus)

REST-governed gene expression profiling in a neuronal cell model reveals novel direct and indirect processes of repression and up-regulation

Garcia-Manteiga, J. M., Bonfiglio, S., Folladori, L., Malosio, M. L., Lazarevic, D., Stupka, E., Cittaro, D. & Meldolesi, J., Nov 10 2015, In : Frontiers in Cellular Neuroscience. 9, NOVEMBER, 438.

Research output: Contribution to journalArticle

Gene Expression Profiling
Up-Regulation
Genes
Clone Cells
Neurons
2014
7 Citations (Scopus)
Islets of Langerhans
Magnetic Resonance Spectroscopy
Perfusion
Liver
Magnetic Resonance Imaging
2013
49 Citations (Scopus)

Tyrosine Kinase signal modulation: A matter of H2O2 membrane permeability?

Bertolotti, M., Bestetti, S., García-Manteiga, J. M., Medraño-Fernandez, I., Dal Mas, A., Malosio, M. L. & Sitia, R., Nov 1 2013, In : Antioxidants and Redox Signaling. 19, 13, p. 1447-1451 5 p.

Research output: Contribution to journalArticle

Protein-Tyrosine Kinases
Permeability
Modulation
Membranes
Phosphorylation
2010
29 Citations (Scopus)

On/off TLR signaling decides proinflammatory or tolerogenic dendritic cell maturation upon CD1D-mediated interaction with invariant NKT cells

Caielli, S., Conforti-Andreoni, C., Di Pietro, C., Usuelli, V., Badami, E., Malosio, M. L. & Falcone, M., Dec 15 2010, In : Journal of Immunology. 185, 12, p. 7317-7329 13 p.

Research output: Contribution to journalArticle

Natural Killer T-Cells
Dendritic Cells
Immune Tolerance
CD40 Ligand
MAP Kinase Signaling System
2009
66 Citations (Scopus)

Antiacquaporin 4 antibodies detection by different techniques in neuromyelitis optica patients

Fazio, R., Malosio, M. L., Lampasona, V., De Feo, D., Privitera, D., Marnetto, F., Centonze, D., Ghezzi, A., Comi, G., Furlan, R. & Martino, G., 2009, In : Multiple Sclerosis Journal. 15, 10, p. 1153-1163 11 p.

Research output: Contribution to journalArticle

Neuromyelitis Optica
Aquaporin 4
Antibodies
Transverse Myelitis
Seroepidemiologic Studies
21 Citations (Scopus)

Improving the procedure for detection of intrahepatic transplanted islets by magnetic resonance imaging

Malosio, M. L., Esposito, A., Poletti, A., Chiaretti, S., Piemonti, L., Melzi, R., Nano, R., Tedoldi, F., Canu, T., Santambrogio, P., Brigatti, C., De Cobelli, F., Maffi, P., Secchi, A. & Del Maschio, A., Oct 2009, In : American Journal of Transplantation. 9, 10, p. 2372-2382 11 p.

Research output: Contribution to journalArticle

Magnets
Magnetic Resonance Imaging
Transplants
Islets of Langerhans Transplantation
Feasibility Studies
2008
9 Citations (Scopus)

Beta cell chromogranin B is partially segregated in distinct granules and can be released separately from insulin in response to stimulation

Giordano, T., Brigatti, C., Podini, P., Bonifacio, E., Meldolesi, J. & Malosio, M. L., Jun 2008, In : Diabetologia. 51, 6, p. 997-1007 11 p.

Research output: Contribution to journalArticle

Chromogranin B
Insulin
trans-Golgi Network
Ionomycin
Computer-Assisted Image Processing
32 Citations (Scopus)

Expression of the neurosecretory process in pc12 cells is governed by rest

D'Alessandro, R., Klajn, A., Stucchi, L., Podini, P., Malosio, M. L. & Meldolesi, J., May 2008, In : Journal of Neurochemistry. 105, 4, p. 1369-1383 15 p.

Research output: Contribution to journalArticle

PC12 Cells
Chromogranins
Exocytosis
Secretory Vesicles
Genes
107 Citations (Scopus)
Tropism
Chemokine Receptors
Adenocarcinoma
Neoplasms
Peripheral Nerves
2006
20 Citations (Scopus)

Monoclonal antibody 76F distinguishes IA-2 from IA-2β and overlaps an autoantibody epitope

Piquer, S., Valera, L., Lampasona, V., Jardin-Watelet, B., Roche, S., Granier, C., Roquet, F., Christie, M. R., Giordano, T., Malosio, M. L., Bonifacio, E. & Laune, D., May 2006, In : Journal of Autoimmunity. 26, 3, p. 215-222 8 p.

Research output: Contribution to journalArticle

Epitopes
Monoclonal Antibodies
Autoantibodies
Autoantigens
Type 1 Diabetes Mellitus
2005
453 Citations (Scopus)

Bone marrow mesenchymal stem cells express a restricted set of functionally active chemokine receptors capable of promoting migration to pancreatic islets

Sordi, V., Malosio, M. L., Marchesi, F., Mercalli, A., Melzi, R., Giordano, T., Belmonte, N., Ferrari, G., Leone, B. E., Bertuzzi, F., Zerbini, G., Allavena, P., Bonifacio, E. & Piemonti, L., Jul 15 2005, In : Blood. 106, 2, p. 419-427 9 p.

Research output: Contribution to journalArticle

Chemokine Receptors
Stem cells
Mesenchymal Stromal Cells
Islets of Langerhans
Bone
2004
55 Citations (Scopus)

Dense-core granules: A specific hallmark of the neuronal/neurosecretory cell phenotype

Malosio, M. L., Giordano, T., Laslop, A. & Meldolesi, J., Feb 15 2004, In : Journal of Cell Science. 117, 5, p. 743-749 7 p.

Research output: Contribution to journalArticle

Chromogranin A
Phenotype
Chromogranin B
Clone Cells
Organelles
38 Citations (Scopus)

Requirements for the identification of dense-core granules

Meldolesi, J., Chieregatti, E. & Malosio, M. L., Jan 2004, In : Trends in Cell Biology. 14, 1, p. 13-19 7 p.

Research output: Contribution to journalArticle

Organelles
Chromogranins
Cytoplasmic Granules
Exocytosis
Electron Microscopy
2002

Erratum: Neurosecretion competence. A comprehensive gene expression program identified in PC12 cells. (Journal of Biological Chemistry (2002) 277 (36715-36724))

Grundschober, C., Malosio, M. L., Astolfi, L., Giordano, T., Nef, P. & Meldolesi, J., Nov 29 2002, In : Journal of Biological Chemistry. 277, 48, p. 46840 1 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Neurosecretion competence. A comprehensive gene expression program identified in PC12 cells

Grundschober, C., Malosio, M. L., Astolfi, L., Giordano, T., Nef, P. & Meldolesi, J., Sep 27 2002, In : Journal of Biological Chemistry. 277, 39, p. 36715-36724 10 p.

Research output: Contribution to journalArticle

Neurosecretion
PC12 Cells
Gene expression
Mental Competency
Clone Cells
1999
78 Citations (Scopus)

Blockade of membrane transport and disassembly of the Golgi complex by expression of syntaxin 1A in neurosecretion-incompetent cells: Prevention by rbSEC1

Rowe, J., Corradi, N., Malosio, M. L., Taverna, E., Halban, P., Meldolesi, J. & Rosa, P., 1999, In : Journal of Cell Science. 112, 12, p. 1865-1877 13 p.

Research output: Contribution to journalArticle

Syntaxin 1
Neurosecretion
Golgi Apparatus
Membranes
SNARE Proteins
18 Citations (Scopus)

Neurosecretory cells without neurosecretion: Evidence of an independently regulated trait of the cell phenotype

Malosio, M. L., Benfante, R., Racchetti, G., Borgonovo, B., Rosa, P. & Meldolesi, J., Oct 1 1999, In : Journal of Physiology. 520, 1, p. 43-52 10 p.

Research output: Contribution to journalArticle

Neurosecretion
Phenotype
Exocytosis
Organelles
Mental Competency
1998
13 Citations (Scopus)

Neurosecretion competence, an independently regulated trait of the neurosecretory cell phenotype

Borgonovo, B., Racchetti, G., Malosio, M., Benfante, R., Podini, P., Rosa, P. & Meldolesi, J., Dec 25 1998, In : Journal of Biological Chemistry. 273, 52, p. 34683-34686 4 p.

Research output: Contribution to journalArticle

Neurosecretion
Mental Competency
Rats
Phenotype
Transcription
1997
60 Citations (Scopus)
rho GTP-Binding Proteins
Genes
Neurites
Nervous System
Vertebrates
1996
3 Citations (Scopus)

Exposure to perinatal morphine promotes developmental changes in rat striatum

Gorio, A., Malosio, M. L., Vergani, L. & Giulio, A. M. D., Jul 1996, In : International Journal of Developmental Neuroscience. 14, 4, p. 471-479 9 p.

Research output: Contribution to journalArticle

Morphine
Dopamine
Methionine Enkephalin
Messenger RNA
Tyrosine 3-Monooxygenase
8 Citations (Scopus)

In situ hybridization study of myelin protein mRNA in rats with an experimental diabetic neuropathy

Conti, A. M., Scarpini, E., Malosio, M. L., Di Giulio, A. M., Baron, P., Scarlato, G., Mantegazza, P. & Gorio, A., Mar 22 1996, In : Neuroscience Letters. 207, 1, p. 65-69 5 p.

Research output: Contribution to journalArticle

Myelin Proteins
Diabetic Neuropathies
Myelin Basic Protein
In Situ Hybridization
Messenger RNA
4 Citations (Scopus)

Perinatal exposure to morphine: Reactive changes in the brain after 6-hydroxydopamine

Gorio, A., Vergani, L., Malosio, M. L., Lesma, E. & Di Giulio, A. M., May 6 1996, In : European Journal of Pharmacology. 303, 1-2, p. 21-26 6 p.

Research output: Contribution to journalArticle

Oxidopamine
Morphine
Synapsins
Brain
Messenger RNA
8 Citations (Scopus)
Retinal Neurons
Laminin
Integrins
Tyrosine
Phosphorylation
1995
10 Citations (Scopus)

Perinatal morphine I: Effects on synapsin and neurotransmitter systems in the brain

Di Giulio, A. M., Tenconi, B., Malosio, M. L., Vergani, L., Bertelli, A. & Gorio, A., 1995, In : Journal of Neuroscience Research. 42, 4, p. 479-485 7 p.

Research output: Contribution to journalArticle

Synapsins
Morphine
Neurotransmitter Agents
Methionine Enkephalin
Substance P
1993
79 Citations (Scopus)

Distribution of gephyrin transcripts in the adult and developing rat brain

Kirsch, J., Malosio, M. L., Wolters, I. & Betz, H., 1993, In : European Journal of Neuroscience. 5, 9, p. 1109-1117 9 p.

Research output: Contribution to journalArticle

Glycine Receptors
Brain
Messenger RNA
Spinal Cord
Oligonucleotide Probes
8 Citations (Scopus)

Myelin protein transcripts increase in experimental diabetic neuropathy

Conti, A. M., Malosio, M. L., Scarpini, E., Di Giulio, A. M., Scarlato, G., Mantegazza, P. & Gorio, A., Oct 29 1993, In : Neuroscience Letters. 161, 2, p. 203-206 4 p.

Research output: Contribution to journalArticle

Myelin Proteins
Diabetic Neuropathies
Messenger RNA
Myelin P0 Protein
Insulin
1992

Cellular and molecular mechanisms underlying the effects on neuronal plasticity by substances of abuse such as alcoholand opiates

Gorio, A., Di Giulio, A. M., Tenconi, B., Finco, C., Germani, E., Malosio, M. L., Bertelli, A. & Mantegazza, P., Sep 1992, In : Pharmacological Research. 26, SUPPL. 1, p. 41 1 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Diabetes-induced alterations of central nervous system G proteins - ADP-ribosylation, immunoreactivity, and gene-expression studies in rat striatum

Finco, C., Abbracchio, M. P., Malosio, M. L., Cattabeni, F., Di Giulio, A. M., Paternieri, B., Mantegazza, P. & Gorio, A., Dec 1992, In : Molecular and Chemical Neuropathology. 17, 3, p. 259-272 14 p.

Research output: Contribution to journalArticle

GTP-Binding Proteins
Adenosine Diphosphate
Central Nervous System
Pertussis Toxin
Gene Expression

G-proteins and diabetic encephalopathy: molecular mechanisms underlying the functional alterations

Finco, C., Abbracchio, M. P., Paternieri, B., Cattabeni, F., Di Giulio, A. M., Malosio, M. L., Mantegazza, P. & Gorio, A., 1992, In : Pharmacological Research. 25, SUPPL. 1, p. 109-110 2 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Perinatal morphine exposure alters peptidergic development in the striatum

Tenconi, B., Donadoni, M. L., Finco, C., Germani, E., Malosio, M. L., Di Giulio, A. M., Mantegazza, P. & Gorio, A., 1992, In : International Journal of Developmental Neuroscience. 10, 6, p. 517-526 10 p.

Research output: Contribution to journalArticle

Substance P
Morphine
Opiate Alkaloids
Methionine Enkephalin
Messenger RNA
1991
104 Citations (Scopus)

Alternative splicing generates two isoforms of the α2 subunit of the inhibitory glycine receptor

Kuhse, J., Kuryatov, A., Maulet, Y., Malosio, M. L., Schmieden, V. & Betz, H., May 20 1991, In : FEBS Letters. 283, 1, p. 73-77 5 p.

Research output: Contribution to journalArticle

Glycine Receptors
Alternative Splicing
Protein Isoforms
Rats
Ligand-Gated Ion Channels
101 Citations (Scopus)

Alternative splicing generates two variants of the α1 subunit of the inhibitory glycine receptor

Malosio, M. L., Grenningloh, G., Kuhse, J., Schmieden, V., Schmitt, B., Prior, P. & Betz, H., Feb 5 1991, In : Journal of Biological Chemistry. 266, 4, p. 2048-2053 6 p.

Research output: Contribution to journalArticle

Glycine Receptors
Alternative Splicing
Strychnine
RNA Splice Sites
Spinal Cord
90 Citations (Scopus)

Differential expression of synaptophysin and synaptoporin mRNAs in the postnatal rat central nervous system

Marqueze-Pouey, B., Wisden, W., Malosio, M. L. & Betz, H., 1991, In : Journal of Neuroscience. 11, 11, p. 3388-3397 10 p.

Research output: Contribution to journalArticle

Synaptophysin
Central Nervous System
Messenger RNA
Telencephalon
Oligonucleotide Probes
11 Citations (Scopus)

Heterogeneity of the inhibitory glycine receptor

Kuhse, J., Becker, C. M., Schmieden, V., Hoch, W., Pribilla, I., Langosch, D., Malosio, M. L., Muntz, M. & Betz, H., 1991, In : Annals of the New York Academy of Sciences. 625, p. 129-135 7 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

How to build a glycinergic postsynaptic membrane

Betz, H., Kuhse, J., Schmieden, V., Malosio, M. L., Langosch, D., Prior, P., Schmitt, B. & Kirsch, J., 1991, In : Journal of Cell Science. 100, SUPPL. 15, p. 23-25 3 p.

Research output: Contribution to journalArticle

Glycine Receptors
Protein Isoforms
Chloride Channels
Microtubule-Associated Proteins
Membranes
22 Citations (Scopus)

Structure and expression of inhibitory glycine receptors

Betz, H., Langosch, D., Hoch, W., Prior, P., Pribilla, I., Kuhse, J., Schmieden, V., Malosio, M. L., Matzenbach, B., Holzinger, F., Kuryatov, A., Schmitt, B., Maulet, Y. & Becker, C. M., 1991, In : Advances in Experimental Medicine and Biology. 287, p. 421-430 10 p.

Research output: Contribution to journalArticle

420 Citations (Scopus)

Widespread expression of glycine receptor subunit mRNAs in the adult and developing rat brain

Malosio, M. L., Marquèze-Pouey, B., Kuhse, J. & Betz, H., 1991, In : EMBO Journal. 10, 9, p. 2401-2409 9 p.

Research output: Contribution to journalArticle

Glycine Receptors
Rats
Brain
Messenger RNA
Spinal Cord
1989
1 Citation (Scopus)

Homology and analogy in transmembrane channel design: Lessons from synaptic membrane proteins

Betz, H., Becker, C. M., Grenningloh, G., Hoch, W., Knaus, P., Langosch, D., Malosio, M. L., Schmitt, B. & Thomas, L., Jun 1989, In : Journal of Protein Chemistry. 8, 3, p. 325 1 p.

Research output: Contribution to journalArticle