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Research Output 1990 2019

146. Vastatins inhibit tissue factor in cultured human macrophages

Tremoli, E., Colli, S., Eligini, S., Lalli, M., Camera, M. & Paoletti, R., 1996, In : Fibrinolysis. 10, SUPPL. 1, p. 46 1 p.

Research output: Contribution to journalArticle

Thromboplastin
Macrophages
fluvastatin
Mevalonic Acid
Farnesol
MAP Kinase Signaling System
Thromboplastin
Endothelial Cells
Macrophages
Peroxisome Proliferator-Activated Receptors

ACE-Inhibition Benefit on Lung Function in Heart Failure is Modulated by ACE Insertion/Deletion Polymorphism

Contini, M., Compagnino, E., Cattadori, G., Magrì, D., Camera, M., Apostolo, A., Farina, S., Palermo, P., Gertow, K., Tremoli, E., Fiorentini, C. & Agostoni, P., Feb 4 2016, (Accepted/In press) In : Cardiovascular Drugs and Therapy. p. 1-10 10 p.

Research output: Contribution to journalArticle

Peptidyl-Dipeptidase A
Heart Failure
Genotype
Lung
Angiotensin-Converting Enzyme Inhibitors

Alirocumab after Acute Coronary Syndrome

Pignatelli, P., Camera, M. & Violi, F., May 23 2019, In : The New England journal of medicine. 380, 21, p. 2076

Research output: Contribution to journalArticle

Angiotensin-converting enzyme inhibitors downregulate tissue factor synthesis in monocytes

Napoleone, E., Di Santo, A., Camera, M., Tremoli, E. & Lorenzet, R., 2000, In : Circulation Research. 86, 2, p. 139-143 5 p.

Research output: Contribution to journalArticle

Thromboplastin
Angiotensin-Converting Enzyme Inhibitors
Monocytes
Down-Regulation
Endotoxins

An intense and short-lasting burst of neutrophil activation differentiates early acute myocardial infarction from systemic inflammatory syndromes

Maugeri, N., Rovere-Querini, P., Evangelista, V., Godino, C., Demetrio, M., Baldini, M., Figini, F., Coppi, G., Slavich, M., Camera, M., Bartorelli, A., Marenzi, G., Campana, L., Baldissera, E., Sabbadini, M. G., Cianflone, D., Tremoli, E., D'Angelo, A., Manfredi, A. A. & Maseri, A., Jun 25 2012, In : PLoS One. 7, 6, e39484.

Research output: Contribution to journalArticle

Neutrophil Activation
myocardial infarction
Peroxidase
neutrophils
Platelets

Anti-TNFα agents curb platelet activation in patients with rheumatoid arthritis

Manfredi, A. A., Baldini, M., Camera, M., Baldissera, E., Brambilla, M., Peretti, G., Maseri, A., Rovere-Querini, P., Tremoli, E., Sabbadini, M. G. & Maugeri, N., Jan 27 2016, (Accepted/In press) In : Annals of the Rheumatic Diseases.

Research output: Contribution to journalArticle

Curbs
Platelet Activation
Platelets
Thromboplastin
Rheumatoid Arthritis

Anti-TNFα agents curb platelet activation in patients with rheumatoid arthritis

Manfredi, A. A., Baldini, M., Camera, M., Baldissera, E., Brambilla, M., Peretti, G., Maseri, A., Rovere-Querini, P., Tremoli, E., Sabbadini, M. G. & Maugeri, N., Jan 27 2016, (Accepted/In press) In : Annals of the Rheumatic Diseases.

Research output: Contribution to journalArticle

Curbs
Platelet Activation
Platelets
Thromboplastin
Rheumatoid Arthritis

Anti-TNFα agents curb platelet activation in patients with rheumatoid arthritis

Manfredi, A. A., Baldini, M., Camera, M., Baldissera, E., Brambilla, M., Peretti, G., Maseri, A., Rovere-Querini, P., Tremoli, E., Sabbadini, M. G. & Maugeri, N., Jan 27 2016, (Accepted/In press) In : Annals of the Rheumatic Diseases.

Research output: Contribution to journalArticle

Curbs
Platelet Activation
Platelets
Thromboplastin
Rheumatoid Arthritis

Anti-TNFα agents curb platelet activation in patients with rheumatoid arthritis

Manfredi, A. A., Baldini, M., Camera, M., Baldissera, E., Brambilla, M., Peretti, G., Maseri, A., Rovere-Querini, P., Tremoli, E., Sabbadini, M. G. & Maugeri, N., Aug 1 2016, In : Annals of the Rheumatic Diseases. 75, 8, p. 1511 - 1520 10 p.

Research output: Contribution to journalArticle

Curbs
Platelet Activation
Platelets
Rheumatoid Arthritis
Thromboplastin

Atherogenic lipoproteins and release of plasminogen activator inhibitor-1 (PAI-1) by endothelial cells

Mussoni, L., Madema, P., Camera, M., Bemini, F., Sironi, L., Sirtori, M. & Tremoli, E., 1990, In : Fibrinolysis and Proteolysis. 4, SUPPL. 2, p. 79-81 3 p.

Research output: Contribution to journalArticle

Plasminogen Activator Inhibitor 1
Lipoproteins
Endothelial Cells
LDL Lipoproteins
Plasminogen Inactivators

Atorvastatin and thrombogenicity of the carotid atherosclerotic plaque: The ATROCAP Study

Cortellaro, M., Confrancesco, E., Arbustini, E., Rossi, F., Negri, A., Tremoli, E., Gabrielli, L. & Camera, M., 2002, In : Thrombosis and Haemostasis. 88, 1, p. 41-47 7 p.

Research output: Contribution to journalArticle

Atherosclerotic Plaques
Thromboplastin
Placebos
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Carotid Stenosis

Biological profile of monocyte-derived macrophages in coronary heart disease patients: implications for plaque morphology

Eligini, S., Cosentino, N., Fiorelli, S., Fabbiocchi, F., Niccoli, G., Refaat, H., Camera, M., Calligaris, G., De Martini, S., Bonomi, A., Veglia, F., Fracassi, F., Crea, F., Marenzi, G. & Tremoli, E., Jun 18 2019, In : Scientific Reports. 9, 1, p. 8680

Research output: Contribution to journalArticle

Coronary Disease
Macrophages
Coronary Artery Disease
Healthy Volunteers
Optical Coherence Tomography

Biology and role of extracellular vesicles (Evs) in the pathogenesis of thrombosis

Zarà, M., Guidetti, G. F., Camera, M., Canobbio, I., Amadio, P., Torti, M., Tremoli, E. & Barbieri, S. S., Jun 1 2019, In : International Journal of Molecular Sciences. 20, 11, 2840.

Research output: Contribution to journalReview article

Open Access
thrombosis
pathogenesis
biology
Tissue homeostasis
Thrombosis

Chemotactic effect of prorenin on human aortic smooth muscle cells: A novel function of the (pro)renin receptor

Greco, C. M., Camera, M., Facchinetti, L., Brambilla, M., Pellegrino, S., Gelmi, M. L., Tremoli, E., Corsini, A. & Ferri, N., 2012, In : Cardiovascular Research. 95, 3, p. 366-374 9 p.

Research output: Contribution to journalArticle

Renin
Smooth Muscle Myocytes
Cell Movement
Guanosine Triphosphate
Focal Adhesions

Cholesterol-induced thrombogenicity of the vessel wall: Inhibitory effect of fluvastatin

Camera, M., Toschi, V., Comparato, C., Baetta, R., Rossi, F., Fuortes, M., Ezekowitz, M. D., Paoletti, R. & Tremoli, E., 2002, In : Thrombosis and Haemostasis. 87, 4, p. 748-755 8 p.

Research output: Contribution to journalArticle

fluvastatin
Cholesterol
Hypercholesterolemia
Rabbits
Prenylation

Control of human artery cell proliferation by inhibitors of HMGCoA reductase

Corsini, A., Raiteri, M., Mazzotti, M., Soma, M., Camera, M., Tremoli, E., Fumagalli, R. & Paoletti, R., Sep 1992, In : Pharmacological Research. 26, SUPPL. 1, p. 28 1 p.

Research output: Contribution to journalArticle

Cooperation between VEGF and TNF-α is necessary for exposure of active tissue factor on the surface of human endothelial cells

Camera, M., Giesen, P. L. A., Fallon, J., Aufiero, B. M., Taubman, M., Tremoli, E. & Nemerson, Y., Mar 1999, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 19, 3, p. 531-537 7 p.

Research output: Contribution to journalArticle

Thromboplastin
Vascular Endothelial Growth Factor A
Endothelial Cells
Tumor Necrosis Factor-alpha
Staining and Labeling

D-dimer is associated with arterial and venous coronary artery bypass graft occlusion

Coronary Bypass Grafting: Factors Related to Late Events and Graft Patency (CAGE) study investigators, Jan 1 2018, In : Journal of Thoracic and Cardiovascular Surgery. 155, 1, p. 200-207.e3

Research output: Contribution to journalArticle

Coronary Artery Bypass
Transplants
Odds Ratio
Confidence Intervals
Biomarkers

D-dimer is associated with arterial and venous coronary artery bypass graft occlusion

Parolari, A., Cavallotti, L., Andreini, D., Myasoedova, V., Banfi, C., Camera, M., Poggio, P., Barili, F., Pontone, G., Mussoni, L., Centenaro, C., Alamanni, F., Tremoli, E. & Coronary Bypass Grafting: Factors Related to Late Events and Graft Patency (CAGE) study investigators, Jan 2018, In : Journal of Thoracic and Cardiovascular Surgery. 155, 1, p. 200-207.e3

Research output: Contribution to journalArticle

Coronary Artery Bypass
Transplants
Odds Ratio
Confidence Intervals
Biomarkers

Direct anticoagulant drugs to overcome limitations of vitamin K antagonists. A critical appraisal of data in atrial fibrillation patients

Di Minno, M. N. D., Russolillo, A., Di Minno, A., Camera, M., Parolari, A. & Tremoli, E., Mar 2013, In : Expert Opinion on Emerging Drugs. 18, 1, p. 9-23 15 p.

Research output: Contribution to journalArticle

Vitamin K
Anticoagulants
Atrial Fibrillation
Hemorrhage
Perioperative Period

Distinct roles for PAR1- and PAR2-mediated vasomotor modulation in human arterial and venous conduits

Ballerio, R., Brambilla, M., Colnago, D., Parolari, A., Agrifoglio, M., Camera, M., Tremoli, E. & Mussoni, L., Jan 2007, In : Journal of Thrombosis and Haemostasis. 5, 1, p. 174-180 7 p.

Research output: Contribution to journalArticle

PAR-2 Receptor
PAR-1 Receptor
Endothelium
Proteinase-Activated Receptors
Vasodilation
Phorbol Esters
Cyclooxygenase 2
Endothelial Cells
Tumor Necrosis Factor-alpha
Glutathione Disulfide

Do methodological differences account for the current controversy on tissue factor expression in platelets?

Brambilla, M., Rossetti, L., Zara, C., Canzano, P., Giesen, P. L. A., Tremoli, E. & Camera, M., Jun 24 2017, (Accepted/In press) In : Platelets. p. 1-9 9 p.

Research output: Contribution to journalArticle

Thromboplastin
Blood Platelets
Platelet-Rich Plasma
Centrifugation
Factor Xa

Effect of atherogenic lipoproteins on PAI-1 synthesis by endothelial cells

Camera, M., Mussoni, L., Maderna, P., Sironi, L., Prati, L., Colli, S., Bernini, F., Corsini, A. & Tremoli, E., Jan 1993, In : Cytotechnology. 11, 1 Supplement

Research output: Contribution to journalArticle

Polyamideimides
Lipoproteins
Plasminogen Activator Inhibitor 1
Endothelial cells
Endothelial Cells
Thromboxanes
Aspirin
Blood Platelets
Coronary Artery Bypass
Transplants

Eicosanoids and Their Drugs in Cardiovascular Diseases: Focus on Atherosclerosis and Stroke

Capra, V., Bäck, M., Barbieri, S. S., Camera, M., Tremoli, E. & Rovati, G. E., Mar 2013, In : Medicinal Research Reviews. 33, 2, p. 364-438 75 p.

Research output: Contribution to journalArticle

Thromboxane A2
Eicosanoids
Prostaglandin-Endoperoxide Synthases
Prostaglandins
Atherosclerosis

Endothelial activation by aPL: A potential pathogenetic mechanism for the clinical manifestations of the syndrome

Meroni, P. L., Raschi, E., Camera, M., Testoni, C., Nicoletti, F., Tincani, A., Khamashta, M. A., Balestrieri, G., Tremoli, E. & Hess, D. C., 2000, In : Journal of Autoimmunity. 15, 2, p. 237-240 4 p.

Research output: Contribution to journalArticle

Mitral Valve Prolapse
Mitral Valve Insufficiency
Mitral Valve
Osteoprotegerin
Glutathione Disulfide

Endothelial tissue factor induction by T lymphocytes in systemic sclerosis

Della Bella, S., Mussoni, L., Molteni, M., Colli, S., Zulian, C., Camera, M., Tremoli, E. & Scorza, R., 1999, In : Clinical Rheumatology. 18, 1, p. 38-41 4 p.

Research output: Contribution to journalArticle

Systemic Scleroderma
Thromboplastin
Endothelium
T-Lymphocytes
Human Umbilical Vein Endothelial Cells
Carotid Intima-Media Thickness
E-Selectin
Inflammation
Thrombosis
Hydroxymethylglutaryl-CoA Reductase Inhibitors

Fibrillar collagen inhibits cholesterol biosynthesis in human aortic smooth muscle cells

Ferri, N., Roncalli, E., Arnaboldi, L., Fenu, S., Andrukhova, O., Aharinejad, S., Camera, M., Tremoli, E. & Corsini, A., Oct 2009, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 29, 10, p. 1631-1637 7 p.

Research output: Contribution to journalArticle

Fibrillar Collagens
Smooth Muscle Myocytes
Cholesterol
Oxidoreductases
Integrins
fluvastatin
Thromboplastin
Macrophages
Cholesterol
Rabbits

Functionally abnormal monocytes in hypercholesterolemia

Stragliotto, E., Camera, M., Postiglione, A., Sirtori, M., Minno, G. D. & Tremoli, E., 1993, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 13, 6, p. 944-950 7 p.

Research output: Contribution to journalArticle

Hypercholesterolemia
Monocytes
Leukotriene B4
N-Formylmethionine Leucyl-Phenylalanine
Thromboxane B2
Stable Angina
Gene Expression Profiling
Acute Coronary Syndrome
Blood Platelets
Messenger RNA

Human megakaryocytes confer tissue factor to a subset of shed platelets to stimulate thrombin generation

Brambilla, M., Facchinetti, L., Canzano, P., Rossetti, L., Ferri, N., Balduini, A., Abbonante, V., Boselli, D., De Marco, L., Di Minno, M. N. D., Toschi, V., Corsini, A., Tremoli, E. & Camera, M., 2015, In : Thrombosis and Haemostasis. 114, 3, p. 579-592 14 p.

Research output: Contribution to journalArticle

Megakaryocytes
Thromboplastin
Thrombin
Blood Platelets
Megakaryocyte Progenitor Cells
Thromboplastin
Neutrophils
P-Selectin
Blood Platelets
Factor VIIa

Hypertriglyceridemia and regulation of fibrinolytic activity

Mussoni, L., Mannucci, L., Sirtori, M., Camera, M., Maderna, P., Sironi, L. & Tremoli, E., 1992, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 12, 1, p. 19-27 9 p.

Research output: Contribution to journalArticle

Hypertriglyceridemia
Triglycerides
Hyperlipoproteinemia Type IV
Tissue Plasminogen Activator
Coronary Disease
Thromboplastin
Peptidyl-Dipeptidase A
Blood Platelets
Stroke
Megakaryocytes

Increased prothrombotic state lasting as long as one month after on-pump and off-pump coronary surgery

Parolari, A., Mussoni, L., Frigerio, M., Naliato, M., Alamanni, F., Galanti, A., Fiore, G., Veglia, F., Tremoli, E., Biglioli, P. & Camera, M., Aug 2005, In : Journal of Thoracic and Cardiovascular Surgery. 130, 2, p. 303-308 6 p.

Research output: Contribution to journalArticle

Ambulatory Surgical Procedures
Coronary Artery Bypass
Fibrinolysis
Intraoperative Period
Off-Pump Coronary Artery Bypass

Increased synthesis of plasminogen activator inhibitor-1 by cultured human endothelial cells exposed to native and modified LDLs: An LDL receptor-independent phenomenon

Tremoli, E., Camera, M., Maderna, P., Sironi, L., Prati, L., Colli, S., Piovella, F., Bernini, F., Corsini, A. & Mussoni, L., 1993, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 13, 3, p. 338-346 9 p.

Research output: Contribution to journalArticle

LDL Receptors
Plasminogen Activator Inhibitor 1
Endothelial Cells
oxidized low density lipoprotein
Human Umbilical Vein Endothelial Cells

Inhibition of cholesterol biosynthesis as a new antithrombotic strategy

Tremoli, E., Colli, S., Camera, M., Banfi, C. & Mussoni, L., 2001, In : Haematologica. 86, 11 SUPPL. 2, p. 35 1 p.

Research output: Contribution to journalArticle

Carotid Intima-Media Thickness
Coronary Disease
Thrombosis
Inflammation
CD40 Ligand

New anti-thrombotic drugs for stroke prevention

Di Minno, M. N. D., Russolillo, A., Camera, M., Brambilla, M., de Gregorio, A., Tremoli, E. & Di Minno, G., Nov 2011, In : Current Vascular Pharmacology. 9, 6, p. 723-732 10 p.

Research output: Contribution to journalArticle

Stroke
Pharmaceutical Preparations
Recurrence
Registries
Safety

Nonrheumatic calcific aortic stenosis: an overview from basic science to pharmacological prevention

Parolari, A., Loardi, C., Mussoni, L., Cavallotti, L., Camera, M., Biglioli, P., Tremoli, E. & Alamanni, F., Mar 2009, In : European Journal of Cardio-thoracic Surgery. 35, 3, p. 493-504 12 p.

Research output: Contribution to journalArticle

Aortic Valve Stenosis
Pharmacology
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Atherosclerosis
Biological Phenomena

On-pump Cardiac Surgery Enhances Platelet Renewal and Impairs Aspirin Pharmacodynamics: Effects of Improved Dosing Regimens

Cavalca, V., Rocca, B., Veglia, F., Petrucci, G., Porro, B., Myasoedova, V., De Cristofaro, R., Turnu, L., Bonomi, A., Songia, P., Cavallotti, L., Zanobini, M., Camera, M., Alamanni, F., Parolari, A., Patrono, C. & Tremoli, E., Nov 1 2017, In : Clinical Pharmacology and Therapeutics. 102, 5, p. 849-858 10 p.

Research output: Contribution to journalArticle

Aspirin
Thoracic Surgery
Blood Platelets
Interleukin-6
Inflammation

Opposite changes of ADAMTS-13 and von Willebrand factor after cardiac surgery [7]

Mannucci, P. M., Parolari, A., Canciani, M. T., Alemanni, F. & Camera, M., Feb 2005, In : Journal of Thrombosis and Haemostasis. 3, 2, p. 397-399 3 p.

Research output: Contribution to journalArticle

Overcoming limitations of current antiplatelet drugs: A concerted effort for more profitable strategies of intervention

Minno, M. N. D. D., Guida, A., Camera, M., Colli, S., Minno, G. D. & Tremoli, E., Nov 2011, In : Annals of Medicine. 43, 7, p. 531-544 14 p.

Research output: Contribution to journalArticle

Platelet Aggregation Inhibitors
Thienopyridines
Blood Platelets
Myocardial Infarction
Stroke