If you made any changes in Pure these will be visible here soon.

Research Output 2017 2019

Filter
Article
2017

1000 Genomes-based metaanalysis identifies 10 novel loci for kidney function

Gorski, M., Van Der Most, P. J., Teumer, A., Chu, A. Y., Li, M., Mijatovic, V., Nolte, I. M., Cocca, M., Taliun, D., Gomez, F., Li, Y., Tayo, B., Tin, A., Feitosa, M. F., Aspelund, T., Attia, J., Biffar, R., Bochud, M., Boerwinkle, E., Borecki, I. & 106 others, Bottinger, E. P., Chen, M. H., Chouraki, V., Ciullo, M., Coresh, J., Cornelis, M. C., Curhan, G. C., D'Adamo, A. P., Dehghan, A., Dengler, L., Ding, J., Eiriksdottir, G., Endlich, K., Enroth, S., Esko, T., Franco, O. H., Gasparini, P., Gieger, C., Girotto, G., Gottesman, O., Gudnason, V., Gyllensten, U., Hancock, S. J., Harris, T. B., Helmer, C., Höllerer, S., Hofer, E., Hofman, A., Holliday, E. G., Homuth, G., Hu, F. B., Huth, C., Hutri-Kähönen, N., Hwang, S. J., Imboden, M., Johansson, A., Kähönen, M., König, W., Kramer, H., Krämer, B. K., Kumar, A., Kutalik, Z., Lambert, J. C., Launer, L. J., Lehtimäki, T., De Borst, M. H., Navis, G., Swertz, M., Liu, Y., Lohman, K., Loos, R. J. F., Lu, Y., Lyytikäinen, L. P., McEvoy, M. A., Meisinger, C., Meitinger, T., Metspalu, A., Metzger, M., Mihailov, E., Mitchell, P., Nauck, M., Oldehinkel, A. J., Olden, M., Penninx, B. W. J. H., Pistis, G., Pramstaller, P. P., Probst-Hensch, N., Raitakari, O. T., Rettig, R., Ridker, P. M., Rivadeneira, F., Robino, A., Rosas, S. E., Ruderfer, D., Ruggiero, D., Saba, Y., Sala, C., Schmidt, H., Schmidt, R., Scott, R. J., Sedaghat, S., Smith, A. V., Sorice, R., Stengel, B., Stracke, S., Strauch, K., Toniolo, D., Uitterlinden, A. G., Ulivi, S., Viikari, J. S., Völker, U., Vollenweider, P., Völzke, H., Vuckovic, D., Waldenberger, M., Wang, J. J., Yang, Q., Chasman, D. I., Tromp, G., Snieder, H., Heid, I. M., Fox, C. S., Köttgen, A., Pattaro, C., Böger, C. A. & Fuchsberger, C., Jan 1 2017, In : Scientific Reports. 7, 45040.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Genome
HapMap Project
Kidney
Heart Septum

1000 Genomes-based metaanalysis identifies 10 novel loci for kidney function

Gorski, M., Van Der Most, P. J., Teumer, A., Chu, A. Y., Li, M., Mijatovic, V., Nolte, I. M., Cocca, M., Taliun, D., Gomez, F., Li, Y., Tayo, B., Tin, A., Feitosa, M. F., Aspelund, T., Attia, J., Biffar, R., Bochud, M., Boerwinkle, E., Borecki, I. & 31 others, Bottinger, E. P., Chen, M-H., Chouraki, V., Ciullo, M., Coresh, J., Cornelis, M. C., Curhan, G. C., D'Adamo, A. P., Dehghan, A., Dengler, L., Ding, J., Eiriksdottir, G., Endlich, K., Enroth, S., Esko, T., Franco, O. H., Gasparini, P., Gieger, C., Girotto, G., Gottesman, O., Gudnason, V., Gyllensten, U., Hancock, S. J., Harris, T. B., Helmer, C., Robino, A., Ruggiero, D., Sala, C., Toniolo, D., Ulivi, S. & Gasparini, P., 2017, In : Scientific Reports. 7

Research output: Contribution to journalArticle

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

Warren, H. R., Evangelou, E., Cabrera, C. P., Gao, H., Ren, M., Mifsud, B., Ntalla, I., Surendran, P., Liu, C., Cook, J. P., Kraja, A. T., Drenos, F., Loh, M., Verweij, N., Marten, J., Karaman, I., Segura Lepe, M. P., O'Reilly, P., Knight, J., Snieder, H. & 41 others, Kato, N., He, J., Shyong Tai, E., Abdullah Said, M., Porteous, D., Alver, M., Poulter, N., Farrall, M., Gansevoort, R. T., Padmanabhan, S., Mägi, R., Stanton, A., Connell, J., Bakker, S. J. L., Metspalu, A., Shields, D. C., Thom, S., Brown, M., Sever, P., Esko, T., Hayward, C., van der Harst, P., Saleheen, D., Chowdhury, R., Barbieri, C. M., Robino, A., Sala, C. F., Ciullo, M., Gasparini, P., Toniolo, D., The International Consortium of Blood Pressure (ICBP) 1000G Analyses, The CHD Exome+ Consortium, The ExomeBP Consortium, The T2D-GENES Consortium, The GoT2DGenes Consortium, The Cohorts for Heart and Ageing Research in Genome Epidemiology (CHARGE) BP Exome Consortium, The International Genomics of Blood Pressure (iGEN -BP) Consortium, for The UK Biobank CardioMetabolic Consortium BP working group Louise, BIOS Consortium, Lifelines Cohort Study & Understanding Society Scientific group, Mar 1 2017, In : Nature Genetics. 49, 3, p. 403-415 13 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Blood Pressure
Cardiovascular Diseases
Precision Medicine
Computer Simulation

Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

Joshi, P. K., Pirastu, N., Kentistou, K. A., Fischer, K., Hofer, E., Schraut, K. E., Clark, D. W., Nutile, T., Barnes, C. L. K., Timmers, P. R. H. J., Shen, X., Gandin, I., McDaid, A. F., Hansen, T. F., Gordon, S. D., Giulianini, F., Boutin, T. S., Abdellaoui, A., Zhao, W., Medina-Gomez, C. & 93 others, Bartz, T. M., Trompet, S., Lange, L. A., Raffield, L., Van Der Spek, A., Galesloot, T. E., Proitsi, P., Yanek, L. R., Bielak, L. F., Payton, A., Murgia, F., Concas, M. P., Biino, G., Tajuddin, S. M., Seppälä, I., Amin, N., Boerwinkle, E., Børglum, A. D., Campbell, A., Demerath, E. W., Demuth, I., Faul, J. D., Ford, I., Gialluisi, A., Gögele, M., Graff, M., Hingorani, A., Hottenga, J. J., Hougaard, D. M., Hurme, M. A., Ikram, M. A., Jylhä, M., Kuh, D., Ligthart, L., Lill, C. M., Lindenberger, U., Lumley, T., Mägi, R., Marques-Vidal, P., Medland, S. E., Milani, L., Nagy, R., Ollier, W. E. R., Peyser, P. A., Pramstaller, P. P., Ridker, P. M., Rivadeneira, F., Ruggiero, D., Saba, Y., Schmidt, R., Schmidt, H., Slagboom, P. E., Smith, B. H., Smith, J. A., Sotoodehnia, N., Steinhagen-Thiessen, E., Van Rooij, F. J. A., Verbeek, A. L., Vermeulen, S. H., Vollenweider, P., Wang, Y., Werge, T., Whitfield, J. B., Zonderman, A. B., Lehtimäki, T., Evans, M. K., Pirastu, M., Fuchsberger, C., Bertram, L., Pendleton, N., Kardia, S. L. R., Ciullo, M., Becker, D. M., Wong, A., Psaty, B. M., Van Duijn, C. M., Wilson, J. G., Jukema, J. W., Kiemeney, L., Uitterlinden, A. G., Franceschini, N., North, K. E., Weir, D. R., Metspalu, A., Boomsma, D. I., Hayward, C., Chasman, D., Martin, N. G., Sattar, N., Campbell, H., Esko, T., Kutalik, Z. & Wilson, J. F., Dec 1 2017, In : Nature Communications. 8, 1, 910.

Research output: Contribution to journalArticle

HLA-DRB1 Chains
genome
coronary artery disease
Meta-Analysis
Life Style

Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

Day, F. R., Thompson, D. J., Helgason, H., Chasman, D. I., Finucane, H., Sulem, P., Ruth, K. S., Whalen, S., Sarkar, A. K., Albrecht, E., Altmaier, E., Amini, M., Barbieri, C. M., Boutin, T., Campbell, A., Demerath, E., Giri, A., He, C., Hottenga, J. J., Karlsson, R. & 30 others, Kolcic, I., Loh, P-R., Lunetta, K. L., Mangino, M., Marco, B., McMahon, G., Medland, S. E., Nolte, I. M., Noordam, R., Nutile, T., Paternoster, L., Perjakova, N., Porcu, E., Rose, L. M., Schraut, K. E., Segrè, A. V., Smith, A. V., Stolk, L., Teumer, A., Andrulis, I. L., Catamo, E., Joshi, P. K., Lenarduzzi, S., Radice, P., Robino, A., Ruggiero, D., Sala, C. F., Ciullo, M., Toniolo, D. & Ulivi, S., 2017, In : Nature Genetics. 49, 6, p. 834-841 8 p.

Research output: Contribution to journalArticle

Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

Day, F. R., Thompson, D. J., Helgason, H., Chasman, D. I., Finucane, H., Sulem, P., Ruth, K. S., Whalen, S., Sarkar, A. K., Albrecht, E., Altmaier, E., Amini, M., Barbieri, C. M., Boutin, T., Campbell, A., Demerath, E., Giri, A., He, C., Hottenga, J. J., Karlsson, R. & 196 others, Kolcic, I., Loh, P. R., Lunetta, K. L., Mangino, M., Marco, B., McMahon, G., Medland, S. E., Nolte, I. M., Noordam, R., Nutile, T., Paternoster, L., Perjakova, N., Porcu, E., Rose, L. M., Schraut, K. E., Segrè, A. V., Smith, A. V., Stolk, L., Teumer, A., Andrulis, I. L., Bandinelli, S., Beckmann, M. W., Benitez, J., Bergmann, S., Bochud, M., Boerwinkle, E., Bojesen, S. E., Bolla, M. K., Brand, J. S., Brauch, H., Brenner, H., Broer, L., Brüning, T., Buring, J. E., Campbell, H., Catamo, E., Chanock, S., Chenevix-Trench, G., Corre, T., Couch, F. J., Cousminer, D. L., Cox, A., Crisponi, L., Czene, K., Davey Smith, G., De Geus, E. J. C. N., De Mutsert, R., De Vivo, I., Dennis, J., Devilee, P., Dos-Santos-Silva, I., Dunning, A. M., Eriksson, J. G., Fasching, P. A., Fernández-Rhodes, L., Ferrucci, L., Flesch-Janys, D., Franke, L., Gabrielson, M., Gandin, I., Giles, G. G., Grallert, H., Gudbjartsson, D. F., Guénel, P., Hall, P., Hallberg, E., Hamann, U., Harris, T. B., Hartman, C. A., Heiss, G., Hooning, M. J., Hopper, J. L., Hu, F., Hunter, D. J., Ikram, M. A., Im, H. K., Järvelin, M. R., Joshi, P. K., Karasik, D., Kellis, M., Kutalik, Z., Lachance, G., Lambrechts, D., Langenberg, C., Launer, L. J., Laven, J. S. E., Lenarduzzi, S., Li, J., Lind, P. A., Lindstrom, S., Liu, Y., Luan, JA., Mägi, R., Mannermaa, A., Mbarek, H., McCarthy, M. I., Meisinger, C., Meitinger, T., Menni, C., Metspalu, A., Michailidou, K., Milani, L., Milne, R. L., Montgomery, G. W., Mulligan, A. M., Nalls, M. A., Navarro, P., Nevanlinna, H., Nyholt, D. R., Oldehinkel, A. J., O'Mara, T. A., Padmanabhan, S., Palotie, A., Pedersen, N., Peters, A., Peto, J., Pharoah, P. D. P., Pouta, A., Radice, P., Rahman, I., Ring, S. M., Robino, A., Rosendaal, F. R., Rudan, I., Rueedi, R., Ruggiero, D., Sala, C. F., Schmidt, M. K., Scott, R. A., Shah, M., Sorice, R., Southey, M. C., Sovio, U., Stampfer, M., Steri, M., Strauch, K., Tanaka, T., Tikkanen, E., Timpson, N. J., Traglia, M., Truong, T., Tyrer, J. P., Uitterlinden, A. G., Edwards, D. R. V., Vitart, V., Völker, U., Vollenweider, P., Wang, Q., Widen, E., Van Dijk, K. W., Willemsen, G., Winqvist, R., Wolffenbuttel, B. H. R., Zhao, J. H., Zoledziewska, M., Zygmunt, M., Alizadeh, B. Z., Boomsma, D. I., Ciullo, M., Cucca, F., Esko, T., Franceschini, N., Gieger, C., Gudnason, V., Hayward, C., Kraft, P., Lawlor, D. A., Magnusson, P. K. E., Martin, N. G., Mook-Kanamori, D. O., Nohr, E. A., Polasek, O., Porteous, D., Price, A. L., Ridker, P. M., Snieder, H., Spector, T. D., Stöckl, D., Toniolo, D., Ulivi, S., Visser, J. A., Völzke, H., Wareham, N. J., Wilson, J. F., Spurdle, A. B., Thorsteindottir, U., Pollard, K. S., Easton, D. F., Tung, J. Y., Chang-Claude, J., Hinds, D., Murray, A., Murabito, J. M., Stefansson, K., Ong, K. K. & Perry, J. R. B., Jun 1 2017, In : Nature Genetics. 49, 6, p. 834-841 8 p.

Research output: Contribution to journalArticle

Menarche
Puberty
Mendelian Randomization Analysis
Multifactorial Inheritance
Neoplasms

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function

Wild, P. S., Felix, J. F., Schillert, A., Teumer, A., Chen, M. H., Leening, M. J. G., Völker, U., Großmann, V., Brody, J. A., Irvin, M. R., Shah, S. J., Pramana, S., Lieb, W., Schmidt, R., Stanton, A. V., Malzahn, D., Smith, A. V., Sundström, J., Minelli, C., Ruggiero, D. & 103 others, Lyytikäinen, L. P., Tiller, D., Smith, J. G., Monnereau, C., Di Tullio, M. R., Musani, S. K., Morrison, A. C., Pers, T. H., Morley, M., Kleber, M. E., Aragam, J., Benjamin, E. J., Bis, J. C., Bisping, E., Broeckel, U., Cheng, S., Deckers, J. W., Del Greco M, F., Edelmann, F., Fornage, M., Franke, L., Friedrich, N., Harris, T. B., Hofer, E., Hofman, A., Huang, J., Hughes, A. D., Kähönen, M., Kruppa, J., Lackner, K. J., Lannfelt, L., Laskowski, R., Launer, L. J., Leosdottir, M., Lin, H., Lindgren, C. M., Loley, C., MacRae, C. A., Mascalzoni, D., Mayet, J., Medenwald, D., Morris, A. P., Müller, C., Müller-Nurasyid, M., Nappo, S., Nilsson, P. M., Nuding, S., Nutile, T., Peters, A., Pfeufer, A., Pietzner, D., Pramstaller, P. P., Raitakari, O. T., Rice, K. M., Rivadeneira, F., Rotter, J. I., Ruohonen, S. T., Sacco, R. L., Samdarshi, T. E., Schmidt, H., Sharp, A. S. P., Shields, D. C., Sorice, R., Sotoodehnia, N., Stricker, B. H., Surendran, P., Thom, S., Töglhofer, A. M., Uitterlinden, A. G., Wachter, R., Völzke, H., Ziegler, A., Münzel, T., März, W., Cappola, T. P., Hirschhorn, J. N., Mitchell, G. F., Smith, N. L., Fox, E. R., Dueker, N. D., Jaddoe, V. W. V., Melander, O., Russ, M., Lehtimäki, T., Ciullo, M., Hicks, A. A., Lind, L., Gudnason, V., Pieske, B., Barron, A. J., Zweiker, R., Schunkert, H., Ingelsson, E., Liu, K., Arnett, D. K., Psaty, B. M., Blankenberg, S., Larson, M. G., Felix, S. B., Franco, O. H., Zeller, T., Vasan, R. S. & Dörr, M., May 1 2017, In : Journal of Clinical Investigation. 127, 5, p. 1798-1812 15 p.

Research output: Contribution to journalArticle

Meta-Analysis
Genetic Loci
Genome-Wide Association Study
Genome
Single Nucleotide Polymorphism

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets from Blood and the Kidney

Wain, LV., Vaez, A., Jansen, R., Joehanes, R., Van Der Most, PJ., Erzurumluoglu, AM., O'Reilly, PF., Cabrera, CP., Warren, HR., Rose, LM., Verwoert, GC., Hottenga, JJ., Strawbridge, RJ., Esko, T., Arking, DE., Hwang, SJ., Guo, X., Kutalik, Z., Trompet, S., Shrine, N. & 224 others, Teumer, A., Ried, JS., Bis, JC., Smith, AV., Amin, N., Nolte, IM., Lyytikäinen, LP., Mahajan, A., Wareham, NJ., Hofer, E., Joshi, PK., Kristiansson, K., Traglia, M., Havulinna, AS., Goel, A., Nalls, MA., Sõber, S., Vuckovic, D., Luan, J., Del Greco, FM., Ayers, KL., Marrugat, J., Ruggiero, D., Lopez, LM., Niiranen, T., Enroth, S., Jackson, AU., Nelson, CP., Huffman, JE., Zhang, W., Marten, J., Gandin, I., Harris, SE., Zemunik, T., Lu, Y., Evangelou, E., Shah, N., De Borst, MH., Mangino, M., Prins, BP., Campbell, A., Li-Gao, R., Chauhan, G., Oldmeadow, C., Abecasis, G., Abedi, M., Barbieri, CM., Barnes, MR., Batini, C., Beilby, J., Consortium, BIOS., Blake, T., Boehnke, M., Bottinger, EP., Braund, PS., Brown, M., Brumat, M., Campbell, H., Chambers, JC., Cocca, M., Collins, F., Connell, J., Cordell, HJ., Damman, JJ., Davies, G., de Geus, EJ., de Mutsert, R., Deelen, J., Demirkale, Y., Doney, ASF., Dörr, M., Farrall, M., Ferreira, T., Frånberg, M., Gao, H., Giedraitis, V., Gieger, C., Giulianini, F., Gow, AJ., Hamsten, A., Harris, TB., Hofman, A., Holliday, EG., Hui, J., Jarvelin, MR., Johansson, Å., Johnson, AD., Jousilahti, P., Jula, A., Kähönen, M., Kathiresan, S., Khaw, KT., Kolcic, I., Koskinen, S., Langenberg, C., Larson, M., Launer, LJ., Lehne, B., Liewald, DCM., Lin, L., Lind, L., Mach, F., Mamasoula, C., Menni, C., Mifsud, B., Milaneschi, Y., Morgan, A., Morris, AD., Morrison, AC., Munson, PJ., Nandakumar, P., Nguyen, QT., Nutile, T., Oldehinkel, AJ., Oostra, BA., Org, E., Padmanabhan, S., Palotie, A., Paré, G., Pattie, A., Penninx, BWJH., Poulter, N., Pramstaller, PP., Raitakari, OT., Ren, M., Rice, K., Ridker, PM., Riese, H., Ripatti, S., Robino, A., Rotter, JI., Rudan, I., Saba, Y., Saint Pierre, A., Sala, CF., Sarin, AP., Schmidt, R., Scott, R., Seelen, MA., Shields, DC., Siscovick, D., Sorice, R., Stanton, A., Stott, DJ., Sundström, J., Swertz, M., Taylor, KD., Thom, S., Tzoulaki, I., Tzourio, C., Uitterlinden, AG., Völker, U., Vollenweider, P., Wild, S., Willemsen, G., Wright, AF., Yao, J., Thériault, S., Conen, D., Attia, J., Sever, P., Debette, S., Mook-Kanamori, DO., Zeggini, E., Spector, TD., van der Harst, P., Palmer, CNA., Vergnaud, AC., Loos, RJF., Polasek, O., Starr, JM., Girotto, G., Hayward, C., Kooner, JS., Lindgren, CM., Vitart, V., Samani, NJ., Tuomilehto, J., Gyllensten, U., Knekt, P., Deary, IJ., Ciullo, M., Elosua, R., Keavney, BD., Hicks, AA., Scott, RA., Gasparini, P., Laan, M., Liu, Y., Watkins, H., Hartman, CA., Salomaa, V., Toniolo, D., Perola, M., Wilson, JF., Schmidt, H., Zhao, JH., Lehtimäki, T., CM, V. D., Gudnason, V., Psaty, BM., Peters, A., Rettig, R., James, A., Jukema, JW., Strachan, DP., Palmas, W., Metspalu, A., Ingelsson, E., Boomsma, DI., Franco, OH., Bochud, M., Newton-Cheh, C., Munroe, PB., Elliott, P., Chasman, DI., Chakravarti, A., Knight, J., Morris, AP., Levy, D., Tobin, MD., Snieder, H., Caulfield, MJ. & Ehret, GB., 2017, In : Hypertension. 70, 3, p. e4-e19

Research output: Contribution to journalArticle

Genome-Wide Association Study
Genetic Association Studies
Blood Pressure
Kidney
Genes

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets from Blood and the Kidney

Wain, L. V., Vaez, A., Jansen, R., Joehanes, R., Van Der Most, P. J., Erzurumluoglu, A. M., O'Reilly, P. F., Cabrera, C. P., Warren, H. R., Rose, L. M., Verwoert, G. C., Hottenga, J. J., Strawbridge, R. J., Esko, T., Arking, D. E., Hwang, S. J., Guo, X., Kutalik, Z., Trompet, S., Shrine, N. & 223 others, Teumer, A., Ried, J. S., Bis, J. C., Smith, A. V., Amin, N., Nolte, I. M., Lyytikäinen, L. P., Mahajan, A., Wareham, N. J., Hofer, E., Joshi, P. K., Kristiansson, K., Traglia, M., Havulinna, A. S., Goel, A., Nalls, M. A., Sõber, S., Vuckovic, D., Luan, JA., Del Greco, F. M., Ayers, K. L., Marrugat, J., Ruggiero, D., Lopez, L. M., Niiranen, T., Enroth, S., Jackson, A. U., Nelson, C. P., Huffman, J. E., Zhang, W., Marten, J., Gandin, I., Harris, S. E., Zemunik, T., Lu, Y., Evangelou, E., Shah, N., De Borst, M. H., Mangino, M., Prins, B. P., Campbell, A., Li-Gao, R., Chauhan, G., Oldmeadow, C., Abecasis, G., Abedi, M., Barbieri, C. M., Barnes, M. R., Batini, C., Beilby, J., Blake, T., Boehnke, M., Bottinger, E. P., Braund, P. S., Brown, M., Brumat, M., Campbell, H., Chambers, J. C., Cocca, M., Collins, F., Connell, J., Cordell, H. J., Damman, J. J., Davies, G., De Geus, E. J., De Mutsert, R., Deelen, J., Demirkale, Y., Doney, A. S. F., Dörr, M., Farrall, M., Ferreira, T., Frånberg, M., Gao, H., Giedraitis, V., Gieger, C., Giulianini, F., Gow, A. J., Hamsten, A., Harris, T. B., Hofman, A., Holliday, E. G., Hui, J., Jarvelin, M. R., Johansson, Å., Johnson, A. D., Jousilahti, P., Jula, A., Kähönen, M., Kathiresan, S., Khaw, K. T., Kolcic, I., Koskinen, S., Langenberg, C., Larson, M., Launer, L. J., Lehne, B., Liewald, D. C. M., Lin, L., Lind, L., Mach, F., Mamasoula, C., Menni, C., Mifsud, B., Milaneschi, Y., Morgan, A., Morris, A. D., Morrison, A. C., Munson, P. J., Nandakumar, P., Nguyen, Q. T., Nutile, T., Oldehinkel, A. J., Oostra, B. A., Org, E., Padmanabhan, S., Palotie, A., Paré, G., Pattie, A., Penninx, B. W. J. H., Poulter, N., Pramstaller, P. P., Raitakari, O. T., Ren, M., Rice, K., Ridker, P. M., Riese, H., Ripatti, S., Robino, A., Rotter, J. I., Rudan, I., Saba, Y., Saint Pierre, A., Sala, C. F., Sarin, A. P., Schmidt, R., Scott, R., Seelen, M. A., Shields, D. C., Siscovick, D., Sorice, R., Stanton, A., Stott, D. J., Sundström, J., Swertz, M., Taylor, K. D., Thom, S., Tzoulaki, I., Tzourio, C., Uitterlinden, A. G., Völker, U., Vollenweider, P., Wild, S., Willemsen, G., Wright, A. F., Yao, J., Thériault, S., Conen, D., Attia, J., Sever, P., Debette, S., Mook-Kanamori, D. O., Zeggini, E., Spector, T. D., Van Der Harst, P., Palmer, C. N. A., Vergnaud, A. C., Loos, R. J. F., Polasek, O., Starr, J. M., Girotto, G., Hayward, C., Kooner, J. S., Lindgren, C. M., Vitart, V., Samani, N. J., Tuomilehto, J., Gyllensten, U., Knekt, P., Deary, I. J., Ciullo, M., Elosua, R., Keavney, B. D., Hicks, A. A., Scott, R. A., Gasparini, P., Laan, M., Liu, Y., Watkins, H., Hartman, C. A., Salomaa, V., Toniolo, D., Perola, M., Wilson, J. F., Schmidt, H., Zhao, J. H., Lehtimäki, T., Van Duijn, C. M., Gudnason, V., Psaty, B. M., Peters, A., Rettig, R., James, A., Jukema, J. W., Strachan, D. P., Palmas, W., Metspalu, A., Ingelsson, E., Boomsma, D. I., Franco, O. H., Bochud, M., Newton-Cheh, C., Munroe, P. B., Elliott, P., Chasman, D. I., Chakravarti, A., Knight, J., Morris, A. P., Levy, D., Tobin, M. D., Snieder, H., Caulfield, M. J. & Ehret, G. B., Sep 1 2017, In : Hypertension. 70, 3, p. e4-e19

Research output: Contribution to journalArticle

Genome-Wide Association Study
Genetic Association Studies
Blood Pressure
Kidney
Genes
Genome-Wide Association Study
Genetic Association Studies
Blood Pressure
Kidney
Genes
2018

A transnational collaborative network dedicated to the study and applications of the vascular endothelial growth factor-A in medical practice: The VEGF Consortium

Stathopoulou, M. G., Xie, T., Ruggiero, D., Chatelin, J., Rancier, M., Weryha, G., Kurth, M. J., Aldasoro Arguinano, A. A., Gorenjak, V., Petrelis, A. M., Dagher, G., Dedoussis, G., Deloukas, P., Lamont, J., Marc, J., Simmaco, M., Schaik, R. H. N. V., Innocenti, F., Merlin, J. L., Schneider, J. & 4 others, Alizadeh, B. Z., Ciullo, M., Seshadri, S. & Visvikis-Siest, S., Mar 28 2018, In : Clinical Chemistry and Laboratory Medicine. p. 83-86 4 p.

Research output: Contribution to journalArticle

Detecting the dominance component of heritability in isolated and outbred human populations

Herzig, A. F., Nutile, T., Ruggiero, D., Ciullo, M., Perdry, H. & Leutenegger, A. L., Dec 1 2018, In : Scientific Reports. 8, 1, 18048.

Research output: Contribution to journalArticle

Population
Medical Genetics
LDL Lipoproteins
Analysis of Variance
Datasets

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

the Million Veteran Program, Oct 1 2018, In : Nature Genetics. 50, 10, p. 1412-1425 14 p.

Research output: Contribution to journalArticle

Blood Pressure
Cardiovascular Diseases
Genetic Association Studies
Life Style
Hypertension

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

LifeLines Cohort Study & CHARGE Inflammation Working Group, Nov 1 2018, In : American Journal of Human Genetics. 103, 5, p. 691-706 16 p.

Research output: Contribution to journalArticle

C-Reactive Protein
Genome
Inflammation
Mendelian Randomization Analysis
Genome-Wide Association Study

Large-scale whole-exome sequencing association studies identify rare functional variants influencing serum urate levels

Tin, A., Li, Y., Brody, J. A., Nutile, T., Chu, A. Y., Huffman, J. E., Yang, Q., Chen, M. H., Robinson-Cohen, C., Macé, A., Liu, J., Demirkan, A., Sorice, R., Sedaghat, S., Swen, M., Yu, B., Ghasemi, S., Teumer, A., Vollenweider, P., Ciullo, M. & 15 others, Li, M., Uitterlinden, A. G., Kraaij, R., Amin, N., van Rooij, J., Kutalik, Z., Dehghan, A., McKnight, B., van Duijn, C. M., Morrison, A., Psaty, B. M., Boerwinkle, E., Fox, C. S., Woodward, O. M. & Köttgen, A., Dec 1 2018, In : Nature Communications. 9, 1, 4228.

Research output: Contribution to journalArticle

Exome
sequencing
Uric Acid
serums
Gout

Strategies for phasing and imputation in a population isolate

Herzig, A. F., Nutile, T., Babron, M. C., Ciullo, M., Bellenguez, C. & Leutenegger, A. L., Mar 1 2018, In : Genetic Epidemiology. 42, 2, p. 201-213 13 p.

Research output: Contribution to journalArticle

Software
Population
Genotype
Chromosomes, Human, Pair 10
Genetic Heterogeneity
2019

A catalog of genetic loci associated with kidney function from analyses of a million individuals

LifeLines Cohort Study & Ruggiero, D., Jun 2019, In : Nature Genetics. 51, 6, p. 957-972 16 p.

Research output: Contribution to journalArticle

Genetic Loci
Kidney
Glomerular Filtration Rate
Chronic Renal Insufficiency
Translational Medical Research

A catalog of genetic loci associated with kidney function from analyses of a million individuals

Gasparini Paolo, 2019, In : Nature Genetics. 51, 6, p. 957-972 16 p.

Research output: Contribution to journalArticle

Associations of autozygosity with a broad range of human phenotypes

Associations of autozygosity with a broad range of human phenotypes & Ruggiero, D., Oct 31 2019, In : Nature Communications. 10, 1, p. 4957

Research output: Contribution to journalArticle

phenotype
Phenotype
Inbreeding
social factors
fertility

Associations of autozygosity with a broad range of human phenotypes

Gasparini Paolo, 2019, In : Nature Communications. 10, 1

Research output: Contribution to journalArticle

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

Gasparini Paolo, 2019, In : Nature Genetics. 51, 10, p. 1459-1474 16 p.

Research output: Contribution to journalArticle

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

German Chronic Kidney Disease Study & Ruggiero, D., Oct 2019, In : Nature Genetics. 51, 10, p. 1459-1474 16 p.

Research output: Contribution to journalArticle

Uric Acid
Serum
Gout
Genes
Kidney

Whole-Exome Sequencing in the Isolated Populations of Cilento from South Italy

Nutile, T., Ruggiero, D., Herzig, A. F., Tirozzi, A., Nappo, S., Sorice, R., Marangio, F., Bellenguez, C., Leutenegger, A. L. & Ciullo, M., Mar 11 2019, In : Scientific Reports. 9, 1, p. 4059

Research output: Contribution to journalArticle

Exome
Italy
Population Genetics
Gene Frequency
Population