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2011

Enhanced c-Met activity promotes G-CSF-induced mobilization of hematopoietic progenitor cells via ROS signaling

Tesio, M., Golan, K., Corso, S., Giordano, S., Schajnovitz, A., Vagima, Y., Shivtiel, S., Kalinkovich, A., Caione, L., Gammaitoni, L., Laurenti, E., Buss, E. C., Shezen, E., Itkin, T., Kollet, O., Petit, I., Trumpp, A., Christensen, J., Aglietta, M., Piacibello, W. & 1 others, Lapidot, T., Jan 13 2011, In : Blood. 117, 2, p. 419-428 10 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor (EGFR) mutation analysis, gene expression profiling and EGFR protein expression in primary prostate cancer

Peraldo-Neia, C., Migliardi, G., Mello-Grand, M., Montemurro, F., Segir, R., Pignochino, Y., Cavalloni, G., Torchio, B., Mosso, L., Chiorino, G. & Aglietta, M., Jan 25 2011, In : BMC Cancer. 11, 31.

Research output: Contribution to journalArticle

Gene-modified T lymphocytes in the setting of hematopoietic cell transplantation: Potential benefits and possible risks

Sangiolo, D., Leuci, V., Gallo, S., Aglietta, M. & Piacibello, W., May 2011, In : Expert Opinion on Biological Therapy. 11, 5, p. 655-666 12 p.

Research output: Contribution to journalArticle

Hitting multiple targets in HER2-positive breast cancer: Proof of principle or therapeutic opportunity?

Geuna, E., Milani, A., Redana, S., Rossi, V., Valabrega, G., Aglietta, M. & Montemurro, F., Mar 2011, In : Expert Opinion on Pharmacotherapy. 12, 4, p. 549-565 17 p.

Research output: Contribution to journalArticle

Intermittent versus continuous chemotherapy in advanced colorectal cancer: A randomised 'GISCAD' trial

Labianca, R., Sobrero, A., Isa, L., Cortesi, E., Barni, S., Nicolella, D., Aglietta, M., Lonardi, S., Corsi, D., Turci, D., Beretta, G. D., Fornarini, G., Dapretto, E., Floriani, I. & Zaniboni, A., 2011, In : Annals of Oncology. 22, 5, p. 1236-1242 7 p.

Research output: Contribution to journalArticle

International expert consensus on primary systemic therapy in the management of early breast cancer: Highlights of the fourth symposium on primary systemic therapy in the management of operable breast cancer, Cremona, Italy (2010)

Berruti, A., Generali, D., Kaufmann, M., Puztai, L., Curigliano, G., Aglietta, M., Gianni, L., Miller, W. R., Untch, M., Sotiriou, C., Daidone, M., Conte, P., Kennedy, D., Damia, G., Petronini, P., Di Cosimo, S., Bruzzi, P., Dowsett, M., Desmedt, C., Mansel, R. E. & 19 others, Olivetti, L., Tondini, C., Sapino, A., Fenaroli, P., Tortora, G., Thorne, H., Bertolini, F., Ferrozzi, F., Danova, M., Tagliabue, E., de Azambuja, E., Makris, A., Tampellini, M., Dontu, G., Veer, L. V. T., Harris, A. L., Fox, S. B., Dogliotti, L. & Bottini, A., Oct 2011, In : Journal of the National Cancer Institute - Monographs. 43, p. 147-151 5 p.

Research output: Contribution to journalArticle

Long-term follow-up of a comparison of nonmyeloablative allografting with autografting for newly diagnosed myeloma

Giaccone, L., Storer, B., Patriarca, F., Rotta, M., Sorasio, R., Allione, B., Carnevale-Schianca, F., Festuccia, M., Brunello, L., Omedè, P., Bringhen, S., Aglietta, M., Levis, A., Mordini, N., Gallamini, A., Fanin, R., Massaia, M., Palumbo, A., Ciccone, G., Storb, R. & 3 others, Gooley, T. A., Boccadoro, M. & Bruno, B., Jun 16 2011, In : Blood. 117, 24, p. 6721-6727 7 p.

Research output: Contribution to journalArticle

No improvement of survival with reduced- versus high-intensity conditioning for allogeneic stem cell transplants in Ewing tumor patients

Thiel, U., Wawer, A., Wolf, P., Badoglio, M., Santucci, A., Klingebiel, T., Basu, O., Borkhardt, A., Laws, H. J., Kodera, Y., Yoshimi, A., Peters, C., Ladenstein, R., Pession, A., Prete, A., Urban, E. C., Schwinger, W., Bordigoni, P., Salmon, A., Diaz, M. A. & 41 others, Afanasyev, B., Lisukov, I., Morozova, E., Toren, A., Bielorai, B., Korsakas, J., Fagioli, F., Caselli, D., Ehninger, G., Gruhn, B., Dirksen, U., Abdel-Rahman, F., Aglietta, M., Mastrodicasa, E., Torrent, M., Corradini, P., Demeocq, F., Dini, G., Dreger, P., Eyrich, M., Gozdzik, J., Guilhot, F., Holler, E., Koscielniak, E., Messina, C., Nachbaur, D., Sabbatini, R., Oldani, E., Ottinger, H., Ozsahin, H., Schots, R., Siena, S., Stein, J., Sufliarska, S., Unal, A., Ussowicz, M., Schneider, P., Woessmann, W., Jürgens, H., Bregni, M. & Burdach, S., 2011, In : Annals of Oncology. 22, 7, p. 1614-1621 8 p.

Research output: Contribution to journalArticle

Risk evaluation, prophylaxis, and treatment of tumor lysis syndrome: Consensus of an italian expert panel

Pession, A., Masetti, R., Gaidano, G., Tosi, P., Rosti, G., Aglietta, M., Specchia, G. & Porta, F., Aug 2011, In : Advances in Therapy. 28, 8, p. 684-697 14 p.

Research output: Contribution to journalArticle

Transient proteasome inhibition as a strategy to enhance lentiviral transduction of hematopoietic CD34 + cells and T lymphocytes: Implications for the use of low viral doses and large-size vectors

Leuci, V., Mesiano, G., Gammaitoni, L., Cammarata, C., Capellero, S., Todorovic, M., Jordaney, N., Circosta, P., Elia, A., Lesnikova, M., Georges, G. E., Piacibello, W., Fagioli, F., Cignetti, A., Aglietta, M. & Sangiolo, D., Dec 10 2011, In : Journal of Biotechnology. 156, 3, p. 218-226 9 p.

Research output: Contribution to journalArticle

Trastuzumab beyond progression in retrospective analyses: An issue of equal opportunities

Montemurro, F., Redana, S., Geuna, E., Milani, A., Rossi, V., Martinello, R., Valabrega, G. & Aglietta, M., 2011, In : The oncologist. 16, 4, p. 534-536 3 p.

Research output: Contribution to journalArticle

Trastuzumab in the adjuvant setting: A practical review

Rossi, V., Redana, S., Milani, A., Geuna, E., Valabrega, G., Aglietta, M. & Montemurro, F., Mar 2011, In : Therapy. 8, 2, p. 161-177 17 p.

Research output: Contribution to journalArticle

Vatalanib for metastatic gastrointestinal stromal tumour (GIST) resistant to imatinib: Final results of a phase II study

Joensuu, H., De Braud, F., Grignagni, G., De Pas, T., Spitalieri, G., Coco, P., Spreafico, C., Boselli, S., Toffalorio, F., Bono, P., Jalava, T., Kappeler, C., Aglietta, M., Laurent, D. & Casali, P. G., May 24 2011, In : British Journal of Cancer. 104, 11, p. 1686-1690 5 p.

Research output: Contribution to journalArticle

2010

Anthracycline-based adjuvant chemotherapy in breast cancer

Montemurro, F. & Aglietta, M., 2010, In : Lancet. 375, 9729, p. 1871 1 p.

Research output: Contribution to journalArticle

Combined first-stage hepatectomy and colorectal resection in a two-stage hepatectomy strategy for bilobar synchronous liver metastases

Karoui, M., Vigano, L., Goyer, P., Ferrero, A., Luciani, A., Aglietta, M., Delbaldo, C., Cirillo, S., Capussotti, L. & Cherqui, D., Sep 2010, In : British Journal of Surgery. 97, 9, p. 1354-1362 9 p.

Research output: Contribution to journalArticle

Role of trastuzumab in the management of HER2-positive metastatic breast cancer

Milani, A., Montemurro, F., Gioeni, L., Aglietta, M. & Valabrega, G., Nov 23 2010, In : Breast Cancer: Targets and Therapy. 2, p. 93-109 17 p.

Research output: Contribution to journalArticle

Targeting EGFR/HER2 pathways enhances the antiproliferative effect of gemcitabine in biliary tract and gallbladder carcinomas

Pignochino, Y., Sarotto, I., Peraldo-Neia, C., Penachioni, J. Y., Cavalloni, G., Migliardi, G., Casorzo, L., Chiorino, G., Risio, M., Bardelli, A., Aglietta, M. & Leone, F., Nov 18 2010, In : BMC Cancer. 10, 361.

Research output: Contribution to journalArticle

Targeting EGFR/HER2 pathways enhances the antiproliferative effect of gemcitabine in biliary tract and gallbladder carcinomas

Pignochino, Y., Sarotto, I., Peraldo-Neia, C., Penachioni, J. Y., Cavalloni, G., Migliardi, G., Casorzo, L., Chiorino, G., Risio, M., Bardelli, A., Aglietta, M. & Leone, F., 2010, In : BMC Cancer. 10, 1, 631.

Research output: Contribution to journalArticle

Third-line sorafenib after sequential therapy with sunitinib and mtor inhibitors in metastatic renal cell carcinoma

Di Lorenzo, G., Buonerba, C., Federico, P., Rescigno, P., Milella, M., Ortega, C., Aieta, M., D'Aniello, C., Longo, N., Felici, A., Ruggeri, E. M., Palmieri, G., Imbimbo, C., Aglietta, M., De Placido, S. & Mirone, V., Dec 2010, In : European Urology. 58, 6, p. 906-911 6 p.

Research output: Contribution to journalArticle

Trastuzumab with either docetaxel or vinorelbine as first-line treatment for patients with HER2-positive advanced breast cancer: A retrospective comparison

Redana, S., Donadio, M., Nolè, F., Jacomuzzi, M. E., Beano, A., Martinello, R., Sapino, A., Viale, G., Aglietta, M. & Montemurro, F., Feb 1 2010, In : BMC Cancer. 10, 28.

Research output: Contribution to journalArticle

Underuse of anthracyclines in women with HER-2+ advanced breast cancer

Montemurro, F., Rossi, V., Nolè, F., Redana, S., Donadio, M., Martinello, R., Verri, E., Valabrega, G., Rocca, M. C., Jacomuzzi, M. E., Viale, G., Sapino, A. & Aglietta, M., 2010, In : The oncologist. 15, 7, p. 665-672 8 p.

Research output: Contribution to journalArticle

Aromatase inhibitors as adjuvant therapy for breast cancer

Montemurro, F., Aglietta, M. & Mastro, L. D., May 20 2009, In : Journal of Clinical Oncology. 27, 15, p. 2566-2567 2 p.

Research output: Contribution to journalArticle

Efficient transcriptional targeting of human hematopoietic stem cells and blood cell lineages by lentiviral vectors containing the regulatory element of the Wiskott-Aldrich syndrome gene

Leuci, V., Gammaitoni, L., Capellero, S., Sangiolo, D., Mesuraca, M., Bond, H. M., Migliardi, G., Cammarata, C., Aglietta, M., Morrone, G. & Piacibello, W., Nov 2009, In : Stem Cells. 27, 11, p. 2815-2823 9 p.

Research output: Contribution to journalArticle

Hormone receptor-positive early breast cancer: Controversies in the use of adjuvant chemotherapy

Montemurro, F. & Aglietta, M., Dec 2009, In : Endocrine-Related Cancer. 16, 4, p. 1091-1102 12 p.

Research output: Contribution to journalArticle

Incidence and clinical implications of venous thromboembolism in advanced colorectal cancer patients: The 'GISCAD-alternating schedule' study findings

Mandalà, M., Barni, S., Floriani, I., Isa, L., Fornarini, G., Marangolo, M., Mosconi, S., Corsi, D., Rulli, E., Frontini, L., Cortesi, E., Zaniboni, A., Aglietta, M. & Labianca, R., Jan 2009, In : European Journal of Cancer. 45, 1, p. 65-73 9 p.

Research output: Contribution to journalArticle

Phase 2 trial of two courses of cyclophosphamide and etoposide for relapsed high-risk osteosarcoma patients

Massimo, B., Giovanni, G., Stefano, F., Eleonora, B., Adalberto, B. D. P., Sandra, A., Francesco, S., Massimo, A. & Franca, F., Jul 1 2009, In : Cancer. 115, 13, p. 2980-2987 8 p.

Research output: Contribution to journalArticle

Phase 2 trial of two courses of cyclophosphamide and etoposide for relapsed high-risk osteosarcoma patients (Cancer (2009) 115, (2980-2987))

Berger, M., Grignani, G., Ferrari, S., Biasin, E., Brach Del Prever, A., Aliberti, S., Saglio, F., Aglietta, M. & Fagioli, F., Nov 1 2009, In : Cancer. 115, 21, p. 5126 1 p.

Research output: Contribution to journalArticle

Reduced-Intensity Allogeneic Hematopoietic Stem Cell Transplantation in Metastatic Colorectal Cancer as a Novel Adoptive Cell Therapy Approach. The European Group for Blood and Marrow Transplantation Experience

Aglietta, M., Barkholt, L., Schianca, F. C., Caravelli, D., Omazic, B., Minotto, C., Leone, F., Hentschke, P., Bertoldero, G., Capaldi, A., Ciccone, G., Niederwieser, D., Ringdén, O. & Demirer, T., Mar 2009, In : Biology of Blood and Marrow Transplantation. 15, 3, p. 326-335 10 p.

Research output: Contribution to journalArticle

Reply to A. Sánchez-Muñoz et al

Montemurro, F., Del Mastro, L. & Aglietta, M., Dec 10 2009, In : Journal of Clinical Oncology. 27, 35

Research output: Contribution to journalArticle

Sorafenib blocks tumour growth, angiogenesis and metastatic potential in preclinical models of osteosarcoma through a mechanism potentially involving the inhibition of ERK1/2, MCL-1 and ezrin pathways

Pignochino, Y., Grignani, G., Cavalloni, G., Motta, M., Tapparo, M., Bruno, S., Bottos, A., Gammaitoni, L., Migliardi, G., Camussi, G., Alberghini, M., Torchio, B., Ferrari, S., Bussolino, F., Fagioli, F., Picci, P. & Aglietta, M., Dec 10 2009, In : Molecular Cancer. 8, 118.

Research output: Contribution to journalArticle

Translocation-Related Sarcomas

Mertens, F., Antonescu, C. R., Hohenberger, P., Ladanyi, M., Modena, P., D'Incalci, M., Casali, P. G., Aglietta, M. & Alvegård, T., Aug 2009, In : Seminars in Oncology. 36, 4, p. 312-323 12 p.

Research output: Contribution to journalArticle

Trastuzumab beyond disease progression: Case closed?

Valabrega, G., Aglietta, M. & Montemurro, F., Sep 20 2009, In : Journal of Clinical Oncology. 27, 27

Research output: Contribution to journalArticle

2008

Alloreactivity and anti-tumor activity segregate within two distinct subsets of cytokine-induced killer (CIK) cells: Implications for their infusion across major HLA barriers

Sangiolo, D., Martinuzzi, E., Todorovic, M., Vitaggio, K., Vallario, A., Jordaney, N., Carnevale-Schianca, F., Capaldi, A., Geuna, M., Casorzo, L., Nash, R. A., Aglietta, M. & Cignetti, A., Jul 2008, In : International Immunology. 20, 7, p. 841-848 8 p.

Research output: Contribution to journalArticle

Comparison of endorectal magnetic resonance imaging, clinical prognostic factors and nomograms in the local staging of prostate cancer patients treated with radiotherapy

Cirillo, S., Petracchini, M., Bona, C. M., Durando, S., Ortega, C., Vormola, R., Stasi, M., Malinverni, G., Aglietta, M., Regge, D. & Gabriele, P., Jan 2008, In : Tumori. 94, 1, p. 65-69 5 p.

Research output: Contribution to journalArticle

Granulocyte-colony stimulating factor upregulates ErbB2 expression on breast cancer cell lines and converts primary resistance to trastuzumab

Cavalloni, G., Sarotto, I., Pignochino, Y., Gammaitoni, L., Migliardi, G., Sgro, L., Piacibello, W., Risio, M., Aglietta, M. & Leone, F., Aug 2008, In : Anti-Cancer Drugs. 19, 7, p. 689-696 8 p.

Research output: Contribution to journalArticle

Pemetrexed single agent chemotherapy in previously treated patients with locally advanced or metastatic non-small cell lung cancer

Russo, F., Bearz, A., Pampaloni, G., Tirelli, U., Bordonaro, R., Verusio, C., Bian, A. R., Marangolo, M., Bianco, A. R., Grossi, F., Gambi, A., Francini, G., Sogno, G., Manente, P., Gebbia, N., Artioli, F., Ardizzoni, A., Masotti, A., Pozzi, E., Tumolo, S. & 19 others, Passalacqua, R., Casartelli, C., Montanari, F., Colucci, G., Barbera, S., Ricci, S., Trodella, L., Valentini, V., Mantovani, G., Ravaioli, A., Monfardini, S., Barni, S., Felletti, R., Testora, F., Aglietta, M., Ardizzoia, A., Bollina, R., Cruciani, G. & Pasquini, E., Jul 31 2008, In : BMC Cancer. 8, 216.

Research output: Contribution to journalArticle

Poor prognosis osteosarcoma: New therapeutic approach

Fagioli, F., Biasin, E., Mereuta, O. M., Muraro, M., Luksch, R., Ferrari, S., Aglietta, M. & Madon, E., Jun 2008, In : Bone Marrow Transplantation. 41, SUPPL. 2

Research output: Contribution to journalArticle

Refreezing of cord blood hematopoietic stem cells for allogenic transplantation: in vitro and in vivo validation of a clinical phase I/II protocol in European and Italian Good Manufacturing Practice conditions

Gunetti, M., Ferrero, I., Rustichelli, D., Berger, M., Gammaitoni, L., Timeus, F., Piacibello, W., Aglietta, M. & Fagioli, F., Feb 2008, In : Experimental Hematology. 36, 2, p. 235-243 9 p.

Research output: Contribution to journalArticle

Retrospective evaluation of clinical outcomes in patients with HER2-positive advanced breast cancer progressing on trastuzumab-based therapy in the pre-lapatinib era

Montemurro, F., Redana, S., Viale, G., Sanna, G., Donadio, M., Valabrega, G., Del Curto, B., Bottini, A., Botti, G., Paolo Dei Tos, A., Jacomuzzi, M. E., Di Bonito, M., Danese, S., Clavarezza, M., Kulka, J., Di Palma, S., Durando, A., Sapino, A. & Aglietta, M., Oct 1 2008, In : Clinical Breast Cancer. 8, 5, p. 436-442 7 p.

Research output: Contribution to journalArticle

Sustained long-term engraftment and transgene expression of peripheral blood CD34+ cells transduced with third-generation lentiviral vectors

Tesio, M., Gammaitoni, L., Gunetti, M., Leuci, V., Pignochino, Y., Jordaney, N., Capellero, S., Cammarata, C., Caione, L., Migliaretti, G., Fagioli, F., Tabilio, A., Aglietta, M. & Piacibello, W., Jun 2008, In : Stem Cells. 26, 6, p. 1620-1627 8 p.

Research output: Contribution to journalArticle

Transplantation of allogeneic hematopoietic stem cells: An emerging treatment modality for solid tumors

Demirer, T., Barkholt, L., Blaise, D., Pedrazzoli, P., Aglietta, M., Carella, A. M., Bay, J. O., Arpaci, F., Rosti, G., Gurman, G., Niederwieser, D. & Bregni, M., May 2008, In : Nature Clinical Practice Oncology. 5, 5, p. 256-267 12 p.

Research output: Contribution to journalArticle

Trastuzumab-related cardiotoxicity in the herceptin adjuvant trial

Montemurro, F., Redana, S., Valabrega, G., Martinello, R., Aglietta, M. & Palmiero, R., 2008, In : Journal of Clinical Oncology. 26, 12, p. 2052-2053 2 p.

Research output: Contribution to journalArticle

2007

A comparison of allografting with autografting for newly diagnosed myeloma

Bruno, B., Rotta, M., Patriarca, F., Mordini, N., Allione, B., Carnevale-Schianca, F., Giaccone, L., Sorasio, R., Omedè, P., Baldi, I., Bringhen, S., Massaia, M., Aglietta, M., Levis, A., Gallamini, A., Fanin, R., Palumbo, A., Storb, R., Ciccone, G. & Boccadoro, M., Mar 15 2007, In : New England Journal of Medicine. 356, 11, p. 1110-1120 11 p.

Research output: Contribution to journalArticle

Correlation between variation in quality of life and change in hemoglobin level after treatment with epoetin alfa 40,000 IU administered once-weekly

Cartenì, G., Giannetta, L., Ucci, G., De Signoribus, G., Vecchione, A., Pinotti, G., Puglisi, F., Contillo, A., Pezzella, G., Orecchia, S., Beccaglia, P., Adamo, V., Aglietta, M., Alabiso, O., Altavilla, G., Amadori, D., Amunni, G., Bajetta, E., Bobbio Pallavicini, E., Bonsignori, M. & 54 others, Bordonaro, R., Bottini, A., Catalano, G., Chiavacci, A., Cigolari, S., Ciotti, R., Conte, P., Ricci, S., Contillo, A., Contu, A., Cortesi, E., Crispino, S., D'Aprile, M., De Chiara, A., De Signoribus, G., Del Prete, S., Donghi, M., Antonelli, P., Falcone, A., Fioretto, L., Fornasiero, A., Gamucci, T., Ghezzi, P., Giusto, M., Iacono, C., Lombardo, M., Manente, P., Mantovani, G., Marchetti, P., Masina, A., Mattioli, R., Menichetti, E., Minisini, A., Neri, B., Nettuno, R., Palazzo, S., Palmeri, S., Palmiotti, G., Patrone, F., Pezzella, G., Pinotti, G., Pizza, C., Pollera, F., Savarese, A., Savarino, A., Sbalzarini, G., Serravezza, G., Siena, S., Sobrero, A., Surace, G., Vecchione, A., Vietti Ramus, G., Vinante, O. & Zagonel, V., Sep 2007, In : Supportive Care in Cancer. 15, 9, p. 1057-1066 10 p.

Research output: Contribution to journalArticle

Lapatinib: A dual inhibitor of EGFR and HER2 tyrosine kinase activity

Montemurro, F., Valabrega, G. & Aglietta, M., Feb 2007, In : Expert Opinion on Biological Therapy. 7, 2, p. 257-268 12 p.

Research output: Contribution to journalArticle