• 2071 Citations
  • 23 h-Index
20042020
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Research Output 2004 2020

  • 2071 Citations
  • 23 h-Index
  • 75 Article
  • 9 Review article
  • 2 Conference contribution
  • 1 Chapter
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Article
2004
77 Citations (Scopus)

Endothelial cell alignment on cyclically-stretched silicone surfaces

Moretti, M., Prina-Mello, A., Reid, A. J., Barron, V. & Prendergast, P. J., Oct 2004, In : Journal of Materials Science: Materials in Medicine. 15, 10, p. 1159-1164 6 p.

Research output: Contribution to journalArticle

Endothelial cells
Silicones
Endothelial Cells
Substrates
Cardiovascular Physiological Phenomena
47 Citations (Scopus)

Lubricin reduces cartilage-cartilage integration

Schaefer, D. B., Wendt, D., Moretti, M., Jakob, M., Jay, G. D., Heberer, M. & Martin, I., 2004, In : Biorheology. 41, 3-4, p. 503-508 6 p.

Research output: Contribution to journalArticle

Cartilage
Lubrication
Synovial Fluid
Articular Cartilage
Chondrocytes
2005
57 Citations (Scopus)

Effects of in vitro preculture on in vivo development of human engineered cartilage in an ectopic model

Moretti, M., Wendt, D., Dickinson, S. C., Sims, T. J., Hollander, A. P., Kelly, D. J., Prendergast, P. J., Heberer, M. & Martin, I., Sep 2005, In : Tissue Engineering. 11, 9-10, p. 1421-1428 8 p.

Research output: Contribution to journalArticle

Cartilage
Human Development
Chondrocytes
Collagen
Nude Mice
40 Citations (Scopus)

Structural characterization and reliable biomechanical assessment of integrative cartilage repair

Moretti, M., Wendt, D., Schaefer, D., Jakob, M., Hunziker, E. B., Heberer, M. & Martin, I., Sep 2005, In : Journal of Biomechanics. 38, 9, p. 1846-1854 9 p.

Research output: Contribution to journalArticle

Cartilage
Repair
Composite materials
Collagen
Tissue
2006
80 Citations (Scopus)

The effect of hydrodynamic shear on 3D engineered chondrocyte systems subject to direct perfusion

Raimondi, M. T., Moretti, M., Cioffi, M., Giordano, C., Boschetti, F., Laganà, K. & Pietrabissa, R., 2006, In : Biorheology. 43, 3-4, p. 215-222 8 p.

Research output: Contribution to journalArticle

Hydrodynamics
Chondrocytes
Perfusion
Bioreactors
DNA
2007
22 Citations (Scopus)

Effects of regulatory factors on engineered cardiac tissue in vitro

Cheng, M., Park, H., Engelmayr, G. C., Moretti, M. & Freed, L. E., Nov 1 2007, In : Tissue Engineering. 13, 11, p. 2709-2719 11 p.

Research output: Contribution to journalArticle

Insulin
Insulin-Like Growth Factor I
L-Lactate Dehydrogenase
Angiopoietin-1
Cell Survival
2008
16 Citations (Scopus)
Cartilage
Bioreactors
Tissue Engineering
Tissue engineering
Tissue
7 Citations (Scopus)

An integrated experimental-computational approach for the study of engineered cartilage constructs subjected to combined regimens of hydrostatic pressure and interstitial perfusion

Moretti, M., Freed, L. E., Padera, R. F., Laganà, K., Boschetti, F. & Raimondi, M. T., 2008, In : Bio-Medical Materials and Engineering. 18, 4-5, p. 273-278 6 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Engineered cartilage constructs subject to very low regimens of interstitial perfusion

Raimondi, M. T., Candiani, G., Cabras, M., Cioffi, M., Laganà, K., Moretti, M. & Pietrabissa, R., 2008, In : Biorheology. 45, 3-4, p. 471-478 8 p.

Research output: Contribution to journalArticle

Cartilage
Perfusion
A73025
Chondrocytes
Hyaline Cartilage
58 Citations (Scopus)

Microcirculation within grooved substrates regulates cell positioning and cell docking inside microfluidic channels

Manbachi, A., Shrivastava, S., Cioffi, M., Chung, B. G., Moretti, M., Demirci, U., Yliperttula, M. & Khademhosseini, A., 2008, In : Lab on a Chip - Miniaturisation for Chemistry and Biology. 8, 5, p. 747-754 8 p.

Research output: Contribution to journalArticle

Microcirculation
Microfluidics
Shear stress
Lab-On-A-Chip Devices
Substrates
2009
38 Citations (Scopus)

Insulin-like growth factor-i and slow, bi-directional perfusion enhance the formation of tissue-engineered cardiac grafts

Cheng, M., Moretti, M., Engelmayr, G. C. & Freed, L. E., Mar 1 2009, In : Tissue Engineering - Part A. 15, 3, p. 645-653 9 p.

Research output: Contribution to journalArticle

Insulin
Somatomedins
Grafts
Insulin-Like Growth Factor I
Perfusion
2010
20 Citations (Scopus)

A computational and experimental study inside microfluidic systems: The role of shear stress and flow recirculation in cell docking

Cioffi, M., Moretti, M., Manbachi, A., Chung, B. G., Khademhosseini, A. & Dubini, G., Aug 2010, In : Biomedical Microdevices. 12, 4, p. 619-626 8 p.

Research output: Contribution to journalArticle

Microfluidics
Lab-On-A-Chip Devices
Shear flow
Shear stress
Microchannels
75 Citations (Scopus)

In vitro generation of mechanically functional cartilage grafts based on adult human stem cells and 3D-woven poly(ε-caprolactone) scaffolds

Valonen, P. K., Moutos, F. T., Kusanagi, A., Moretti, M. G., Diekman, B. O., Welter, J. F., Caplan, A. I., Guilak, F. & Freed, L. E., Mar 2010, In : Biomaterials. 31, 8, p. 2193-2200 8 p.

Research output: Contribution to journalArticle

Adult Stem Cells
Cartilage
Stem cells
Grafts
Scaffolds
2011
3 Citations (Scopus)

Biodegradable microcarriers as cell delivery vehicle for in vivo transplantation and magnetic resonance monitoring.

Lovati, A. B., Vianello, E., Talò, G., Recordati, C., Bonizzi, L., Galliera, E., Broggini, M. & Moretti, M., Apr 2011, In : Journal of Biological Regulators and Homeostatic Agents. 25, 2 Suppl

Research output: Contribution to journalArticle

Nanoparticles
Magnetic Resonance Spectroscopy
Transplantation
Cell Tracking
Chondrocytes
15 Citations (Scopus)

Comparative chondrogenesis of human cells in a 3D integrated experimental-computational mechanobiology model

Raimondi, M. T., Bonacina, E., Candiani, G., Laganà, M., Rolando, E., Talò, G., Pezzoli, D., D'Anchise, R., Pietrabissa, R. & Moretti, M., Apr 2011, In : Biomechanics and Modeling in Mechanobiology. 10, 2, p. 259-268 10 p.

Research output: Contribution to journalArticle

Mechanobiology
Biophysics
Chondrogenesis
Oxygen
Cells
37 Citations (Scopus)

How to embed three-dimensional flexible electrodes in microfluidic devices for cell culture applications

Pavesi, A., Piraino, F., Fiore, G. B., Farino, K. M., Moretti, M. & Rasponi, M., May 7 2011, In : Lab on a Chip - Miniaturisation for Chemistry and Biology. 11, 9, p. 1593-1595 3 p.

Research output: Contribution to journalArticle

Lab-On-A-Chip Devices
Cell culture
Microfluidics
Electrodes
Cell Culture Techniques
7 Citations (Scopus)
Cartilage
Tissue Engineering
Oils and fats
Stem cells
Mesenchymal Stromal Cells
20 Citations (Scopus)

Reliable magnetic reversible assembly of complex microfluidic devices: Fabrication, characterization, and biological validation

Rasponi, M., Piraino, F., Sadr, N., Laganà, M., Redaelli, A. & Moretti, M., May 2011, In : Microfluidics and Nanofluidics. 10, 5, p. 1097-1107 11 p.

Research output: Contribution to journalArticle

microfluidic devices
Microfluidics
sealing
assembly
Fabrication
74 Citations (Scopus)

SAM-based cell transfer to photopatterned hydrogels for microengineering vascular-like structures

Sadr, N., Zhu, M., Osaki, T., Kakegawa, T., Yang, Y., Moretti, M., Fukuda, J. & Khademhosseini, A., Oct 2011, In : Biomaterials. 32, 30, p. 7479-7490 12 p.

Research output: Contribution to journalArticle

Hydrogels
Hydrogel
Self assembled monolayers
Blood Vessels
Tissue Engineering
2013
35 Citations (Scopus)

Fabrication of 3D cell-laden hydrogel microstructures through photo-mold patterning

Occhetta, P., Sadr, N., Piraino, F., Redaelli, A., Moretti, M. & Rasponi, M., Sep 2013, In : Biofabrication. 5, 3, 035002.

Research output: Contribution to journalArticle

Hydrogel
Endothelial cells
Polydimethylsiloxane
Green Fluorescent Proteins
Hydrogels
13 Citations (Scopus)
Chondrogenesis
Subcutaneous Fat
Chondrocytes
Coculture Techniques
Mesenchymal Stromal Cells
21 Citations (Scopus)

Orthopedic bioactive implants: Hydrogel enrichment of macroporous titanium for the delivery of mesenchymal stem cells and strontium

Lopa, S., Mercuri, D., Colombini, A., De Conti, G., Segatti, F., Zagra, L. & Moretti, M., Dec 2013, In : Journal of Biomedical Materials Research - Part A. 101, 12, p. 3396-3403 8 p.

Research output: Contribution to journalArticle

Strontium
Hydrogel
Orthopedics
Titanium
Stem cells
2014
1 Citation (Scopus)

A comparative study of diagnostic and imaging techniques for osteoarthritis of the trapezium

Lovati, A. B., Pozzi, A., Bongio, M., Recordati, C., Berzero, G. & Moretti, M., Nov 24 2014, In : Rheumatology. 54, 1, p. 96-103 8 p., keu280.

Research output: Contribution to journalArticle

Diagnostic Imaging
Osteoarthritis
Histology
X-Rays
Bone and Bones
194 Citations (Scopus)

A microfluidic 3D invitro model for specificity of breast cancer metastasis to bone

Bersini, S., Jeon, J. S., Dubini, G., Arrigoni, C., Chung, S., Charest, J. L., Moretti, M. & Kamm, R. D., Mar 2014, In : Biomaterials. 35, 8, p. 2454-2461 8 p.

Research output: Contribution to journalArticle

Microfluidics
Bone
Cells
Breast Neoplasms
Neoplasm Metastasis
6 Citations (Scopus)

Characterization of articular chondrocytes isolated from 211 osteoarthritic patients

Laganà, M., Arrigoni, C., Lopa, S., Sansone, V., Zagra, L., Moretti, M. & Raimondi, M. T., 2014, In : Cell and Tissue Banking. 15, 1, p. 59-66 8 p.

Research output: Contribution to journalArticle

Cartilage
Chondrocytes
Joints
Biopsy
Tissue
15 Citations (Scopus)
Coculture Techniques
Mesenchymal Stromal Cells
Breast Neoplasms
Neoplasm Metastasis
Bone and Bones
41 Citations (Scopus)
Subcutaneous Fat
Stem cells
Mesenchymal Stromal Cells
Adipose Tissue
Knee
12 Citations (Scopus)

Fibrin in intervertebral disc tissue engineering

Colombini, A., Ceriani, C., Banfi, G., Brayda-Bruno, M. & Moretti, M., Dec 1 2014, In : Tissue Engineering - Part B: Reviews. 20, 6, p. 713-721 9 p.

Research output: Contribution to journalArticle

Intervertebral Disc
Tissue Engineering
Fibrin
Tissue engineering
Cells
79 Citations (Scopus)

Generation of 3D functional microvascular networks with human mesenchymal stem cells in microfluidic systems

Jeon, J. S., Bersini, S., Whisler, J. A., Chen, M. B., Dubini, G., Charest, J. L., Moretti, M. & Kamm, R. D., May 1 2014, In : Integrative biology : quantitative biosciences from nano to macro. 6, 5, p. 555-563 9 p.

Research output: Contribution to journalArticle

Microfluidics
Microvessels
Stem cells
Mesenchymal Stromal Cells
Vascular Endothelial Growth Factor A
38 Citations (Scopus)

In vitro models of the metastatic cascade: From local invasion to extravasation

Bersini, S., Jeon, J. S., Moretti, M. & Kamm, R. D., 2014, In : Drug Discovery Today. 19, 6, p. 735-742 8 p.

Research output: Contribution to journalArticle

Lab-On-A-Chip Devices
Controlled Environment
Cell Adhesion
Cell Communication
Blood Cells
2015
11 Citations (Scopus)
Microfluidics
Microvessels
Tumors
Neoplasms
Blood
11 Citations (Scopus)

Arthritic and non-arthritic synovial fluids modulate IL10 and IL1RA gene expression in differentially activated primary human monocytes

Lopa, S., Leijs, M. J. C., Moretti, M., Lubberts, E., van Osch, G. J. V. M. & Bastiaansen-Jenniskens, Y. M., Nov 1 2015, In : Osteoarthritis and Cartilage. 23, 11, p. 1853-1857 5 p.

Research output: Contribution to journalArticle

Synovial Fluid
Gene expression
Interleukin-10
Arthritis
Monocytes
34 Citations (Scopus)

Cartilage graft engineering by co-culturing primary human articular chondrocytes with human bone marrow stromal cells

Sabatino, M. A., Santoro, R., Gueven, S., Jaquiery, C., Wendt, D. J., Martin, I., Moretti, M. & Barbero, A., Dec 1 2015, In : Journal of Tissue Engineering and Regenerative Medicine. 9, 12, p. 1394-1403 10 p.

Research output: Contribution to journalArticle

Cartilage
Chondrocytes
Mesenchymal Stromal Cells
Grafts
Scaffolds
23 Citations (Scopus)
8 Citations (Scopus)

Fabrication of multi-well chips for spheroid cultures and implantable constructs through rapid prototyping techniques

Lopa, S., Piraino, F., Kemp, R. J., Di Caro, C., Lovati, A. B., Di Giancamillo, A., Moroni, L., Peretti, G. M., Rasponi, M. & Moretti, M., Jul 1 2015, In : Biotechnology and Bioengineering. 112, 7, p. 1457-1471 15 p.

Research output: Contribution to journalArticle

Rapid prototyping
Chondrocytes
Glycosaminoglycans
Fibrin
Fabrication
214 Citations (Scopus)

Human 3D vascularized organotypic microfluidic assays to study breast cancer cell extravasation

Jeon, J. S., Bersini, S., Gilardi, M., Dubini, G., Charest, J. L., Moretti, M. & Kamm, R. D., Jan 6 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 1, p. 214-219 6 p.

Research output: Contribution to journalArticle

Microfluidics
Breast Neoplasms
Microvessels
Neoplasms
Adenosine A3 Receptors
14 Citations (Scopus)

In vitro characterization and in vivo behavior of human nucleus pulposus and annulus fibrosus cells in clinical-grade fibrin and collagen-enriched fibrin gels

Colombini, A., Lopa, S., Ceriani, C., Lovati, A. B., Croiset, S. J., Di Giancamillo, A., Lombardi, G., Banfi, G. & Moretti, M., Feb 1 2015, In : Tissue Engineering - Part A. 21, 3-4, p. 793-802 10 p.

Research output: Contribution to journalArticle

Fibrin
Collagen
Gels
Intervertebral Disc
Extracellular Matrix
6 Citations (Scopus)

In vivo evaluation of bone deposition in macroporous titanium implants loaded with mesenchymal stem cells and strontium-enriched hydrogel

Lovati, A. B., Lopa, S., Ò, G. T., Previdi, S., Recordati, C., Mercuri, D., Segatti, F., Zagra, L. & Moretti, M., Feb 1 2015, In : Journal of Biomedical Materials Research - Part B Applied Biomaterials. 103, 2, p. 448-456 9 p.

Research output: Contribution to journalArticle

Strontium
Hydrogel
Titanium
Stem cells
Mesenchymal Stromal Cells
6 Citations (Scopus)

Osteogenic Differentiation of Human and Ovine Bone Marrow Stromal Cells in response to β-Glycerophosphate and Monosodium Phosphate

Bottagisio, M., Lovati, A. B., Lopa, S. & Moretti, M., Aug 1 2015, In : Cellular Reprogramming. 17, 4, p. 235-242 8 p.

Research output: Contribution to journalArticle

Glycerophosphates
Mesenchymal Stromal Cells
Sheep
Phosphates
Alkaline Phosphatase
36 Citations (Scopus)

VA-086 methacrylate gelatine photopolymerizable hydrogels: A parametric study for highly biocompatible 3D cell embedding

Occhetta, P., Visone, R., Russo, L., Cipolla, L., Moretti, M. & Rasponi, M., Jun 1 2015, In : Journal of Biomedical Materials Research - Part A. 103, 6, p. 2109-2117 9 p.

Research output: Contribution to journalArticle

Hydrogels
Methacrylates
Gelatin
Tissue engineering
Light emitting diodes
2016
21 Citations (Scopus)

A 3D vascularized bone remodeling model combining osteoblasts and osteoclasts in a CaP nanoparticle-enriched matrix

Bongio, M., Lopa, S., Gilardi, M., Bersini, S. & Moretti, M., May 1 2016, In : Nanomedicine. 11, 9, p. 1073-1091 19 p.

Research output: Contribution to journalArticle

Bone Remodeling
Osteoblasts
Osteoclasts
Mesenchymal Stromal Cells
Nanoparticles

Advanced glycation end-products: Mechanics of aged collagen from molecule to tissue

Gautieri, A., Passini, F. S., Silván, U., Guizar-Sicairos, M., Carimati, G., Volpi, P., Moretti, M., Schoenhuber, H., Redaelli, A., Berli, M. & Snedeker, J. G., 2016, In : Matrix Biology.

Research output: Contribution to journalArticle

11 Citations (Scopus)

A new strategy for the decellularisation of large equine tendons as biocompatible tendon substitutes

Bottagisio, M., Pellegata, A. F., Boschetti, F., Ferroni, M., Moretti, M. & Lovati, A. B., Jul 1 2016, In : European Cells and Materials. 32, p. 58-73 16 p.

Research output: Contribution to journalArticle

Tendons
Horses
Peracetic Acid
Scaffolds
Fibroblasts
178 Citations (Scopus)

Bioprinting 3D microfibrous scaffolds for engineering endothelialized myocardium and heart-on-a-chip

Zhang, Y. S., Arneri, A., Bersini, S., Shin, S. R., Zhu, K., Goli-Malekabadi, Z., Aleman, J., Colosi, C., Busignani, F., Dell'Erba, V., Bishop, C., Shupe, T., Demarchi, D., Moretti, M., Rasponi, M., Dokmeci, M. R., Atala, A. & Khademhosseini, A., Dec 1 2016, In : Biomaterials. 110, p. 45-59 15 p.

Research output: Contribution to journalArticle

Bioprinting
Hydrogel
Endothelial cells
Blood vessels
Bioreactors

Chondrogenic capability of osteoarthritic chondrocytes from the trapeziometacarpal and hip joints

Lovati, A. B., Colombini, A., Recordati, C., Ceriani, C., Zagra, L., Berzero, G. & Moretti, M., Mar 1 2016, In : Cell and Tissue Banking. 17, 1, p. 171-177 7 p.

Research output: Contribution to journalArticle

Hip Joint
Cartilage
Chondrocytes
Thigh
Glycosaminoglycans
6 Citations (Scopus)

Creep-resistant dextran-based polyurethane foam as a candidate scaffold for bone tissue engineering: Synthesis, chemico-physical characterization, and in vitro and in vivo biocompatibility

Gerges, I., Tamplenizza, M., Lopa, S., Recordati, C., Martello, F., Tocchio, A., Ricotti, L., Arrigoni, C., Milani, P., Moretti, M. & Lenardi, C., Sep 21 2016, In : International Journal of Polymeric Materials. 65, 14, p. 729-740 12 p.

Research output: Contribution to journalArticle

Dextran
Scaffolds (biology)
Dextrans
Biocompatibility
Tissue engineering
35 Citations (Scopus)

Decellularized and Engineered Tendons as Biological Substitutes: A Critical Review

Lovati, A. B., Bottagisio, M. & Moretti, M., 2016, In : Stem Cells International. 2016, 7276150.

Research output: Contribution to journalArticle

Tendons
Rupture
Animal Models
Achilles Tendon
Mesenchymal Stromal Cells
8 Citations (Scopus)

Engineered miniaturized models of musculoskeletal diseases

Bersini, S., Arrigoni, C., Lopa, S., Bongio, M., Martin, I. & Moretti, M., 2016, (Accepted/In press) In : Drug Discovery Today.

Research output: Contribution to journalArticle

Musculoskeletal Diseases
Musculoskeletal System
Human Body
Skeletal Muscle
Animal Models
5 Citations (Scopus)

Gelatin hydrogels via thiol-ene chemistry

Russo, L., Sgambato, A., Visone, R., Occhetta, P., Moretti, M., Rasponi, M., Nicotra, F. & Cipolla, L., Mar 1 2016, In : Monatshefte fur Chemie. 147, 3, p. 587-592 6 p.

Research output: Contribution to journalArticle

Hydrogels
Gelatin
Sulfhydryl Compounds
Hydrogel
Assays

Human in vitro 3D co-culture model to engineer vascularized bone-mimicking tissues combining computational tools and statistical experimental approach

Bersini, S., Gilardi, M., Arrigoni, C., Talò, G., Zamai, M., Zagra, L., Caiolfa, V. & Moretti, M. G., 2016, In : Biomaterials. 76, p. 157-172 16 p.

Research output: Contribution to journalArticle

Coculture Techniques
Bone
Tissue
Engineers
Bone and Bones