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Research Output 1992 2020

  • 80 Article
  • 6 Review article
  • 1 Chapter
  • 1 Conference contribution
2020
Open Access
fibrosis
Untranslated RNA
cues
Fibroblasts
RNA
2019
Open Access
CXC Chemokines
Chemokine Receptors
DNA Methylation
Hyperglycemia
Stem Cells

Automated Segmentation of Fluorescence Microscopy Images for 3D Cell Detection in human-derived Cardiospheres

Salvi, M., Morbiducci, U., Amadeo, F., Santoro, R., Angelini, F., Chimenti, I., Massai, D., Messina, E., Giacomello, A., Pesce, M. & Molinari, F., Dec 1 2019, In : Scientific Reports. 9, 1, 6644.

Research output: Contribution to journalArticle

Open Access
Fluorescence Microscopy
Cell Nucleus
Stem Cell Niche
Mechanical Stress
Membranes

ESC working group on cellular biology of the heart: Position paper for Cardiovascular Research: Tissue engineering strategies combined with cell therapies for cardiac repair in ischaemic heart disease and heart failure

Madonna, R., Van Laake, L. W., Botker, H. E., Davidson, S. M., De Caterina, R., Engel, F. B., Eschenhagen, T., Fernandez-Aviles, F., Hausenloy, D. J., Hulot, J. S., Lecour, S., Leor, J., Menasché, P., Pesce, M., Perrino, C., Prunier, F., Van Linthout, S., Ytrehus, K., Zimmermann, W. H., Ferdinandy, P. & 1 others, Sluijter, J. P. G., Mar 1 2019, In : Cardiovascular Research. 115, 3, p. 488-500 13 p.

Research output: Contribution to journalReview article

Open Access
Tissue Engineering
Cell- and Tissue-Based Therapy
Myocardial Ischemia
Cell Biology
Heart Failure
Cardiovascular system
Pathology
Cardiovascular System
Homeostasis
Signal transduction
2018

Activation of human aortic valve interstitial cells by local stiffness involves YAP-dependent transcriptional signaling

Santoro, R., Scaini, D., Severino, L. U., Amadeo, F., Ferrari, S., Bernava, G., Garoffolo, G., Agrifoglio, M., Casalis, L. & Pesce, M., Oct 1 2018, In : Biomaterials. 181, p. 268-279 12 p.

Research output: Contribution to journalArticle

Aortic Valve
Chemical activation
Stiffness
Atomic force microscopy
Aortic Diseases
Pericardium
Bioreactors
Aortic Valve
Animals
Perfusion

Cell based mechanosensing in vascular patho-biology: More than a simple go-with the flow

Garoffolo, G., Madonna, R., de Caterina, R. & Pesce, M., Dec 1 2018, In : Vascular Pharmacology. 111, p. 7-14 8 p.

Research output: Contribution to journalReview article

Major adverse cardiovascular events in non-valvular atrial fibrillation with chronic obstructive pulmonary disease: the ARAPACIS study

Arapacis Study Collaborators, Mar 26 2018, (Accepted/In press) In : Internal and Emergency Medicine. p. 1-10 10 p.

Research output: Contribution to journalArticle

Ankle Brachial Index
Atrial Fibrillation
Chronic Obstructive Pulmonary Disease
Registries
Cause of Death

Mechanotransduction in Coronary Vein Graft Disease

Ruiter, M. S. & Pesce, M., 2018, In : Frontiers in cardiovascular medicine. 5, p. 20

Research output: Contribution to journalArticle

Veins
Coronary Vessels
Transplants
Saphenous Vein
Coronary Artery Bypass

Versican is differentially regulated in the adventitial and medial layers of human vein grafts

Kenagy, R. D., Kikuchi, S., Evanko, S. P., Ruiter, M. S., Piola, M., Longchamp, A., Pesce, M., Soncini, M., Deglise, S., Fiore, G. B., Haefliger, J-A., Schmidt, T. A., Majesky, M. W., Sobel, M. & Wight, T. N., 2018, In : PLoS One. 13, 9, p. e0204045

Research output: Contribution to journalArticle

Versicans
hyaluronic acid
Adventitia
Grafts
Veins
2017

Acrylate-based materials for heart valve scaffold engineering

Santoro, R., Venkateswaran, S., Amadeo, F., Zhang, R., Brioschi, M., Callanan, A., Agrifoglio, M., Banfi, C., Bradley, M. & Pesce, M., Dec 19 2017, In : Biomaterials Science. 6, 1, p. 154-167 14 p.

Research output: Contribution to journalArticle

Scaffolds
Polymers
Tissue
Elastin
Cell adhesion

Cardiac mechanoperception: A life-long story from early beats to aging and failure

Pesce, M., Messina, E., Chimenti, I. & Beltrami, A. P., Jan 15 2017, In : Stem Cells and Development. 26, 2, p. 77-90 14 p.

Research output: Contribution to journalReview article

Mechanics
Cell Engineering
Growth
Muscle Cells
Signal Transduction

Epigenetic Erasing and Pancreatic Differentiation of Dermal Fibroblasts into Insulin-Producing Cells are Boosted by the Use of Low-Stiffness Substrate

Pennarossa, G., Santoro, R., Manzoni, E. F. M., Pesce, M., Gandolfi, F. & Brevini, T. A. L., Dec 28 2017, (Accepted/In press) In : Stem Cell Reviews and Reports. p. 1-14 14 p.

Research output: Contribution to journalArticle

Epigenomics
Fibroblasts
Insulin
Skin
Azacitidine

Oncoplastic breast surgery: comprehensive review

Bertozzi, N., Pesce, M., Santi, P. L. & Raposio, E., Jun 2017, In : European Review for Medical and Pharmacological Sciences. 21, 11, p. 2572-2585 14 p.

Research output: Contribution to journalArticle

Breast
Segmental Mastectomy
Breast Neoplasms
Mammaplasty
Cosmetics

Stem Cell Spheroids and Ex Vivo Niche Modeling: Rationalization and Scaling-Up

Chimenti, I., Massai, D., Morbiducci, U., Beltrami, A. P., Pesce, M. & Messina, E., Apr 1 2017, In : Journal of Cardiovascular Translational Research. 10, 2, p. 150-166 17 p.

Research output: Contribution to journalReview article

Stem Cells
Preclinical Drug Evaluations
Regenerative Medicine
Bioreactors
Cues
2016

A compact and automated ex vivo vessel culture system for the pulsatile pressure conditioning of human saphenous veins

Piola, M., Prandi, F., Bono, N., Soncini, M., Penza, E., Agrifoglio, M., Polvani, G., Pesce, M. & Fiore, G. B., Mar 1 2016, In : Journal of Tissue Engineering and Regenerative Medicine. 10, 3, p. E204-E215

Research output: Contribution to journalArticle

Saphenous Vein
Grafts
Pressure
Coronary Artery Bypass
Transplants

Feasibility of pig and human-derived aortic valve interstitial cells seeding on fixative-free decellularized animal pericardium

Santoro, R., Consolo, F., Spiccia, M., Piola, M., Kassem, S., Prandi, F., Vinci, M. C., Forti, E., Polvani, G., Fiore, G. B., Soncini, M. & Pesce, M., Feb 1 2016, In : Journal of Biomedical Materials Research - Part B Applied Biomaterials. 104, 2, p. 345-356 12 p.

Research output: Contribution to journalArticle

Fixatives
Pericardium
Aortic Valve
Animals
Swine
Aptitude
Cardiovascular System
Emotions
Heart Failure
Cell Engineering

Full Mimicking of Coronary Hemodynamics for Ex-Vivo Stimulation of Human Saphenous Veins

Piola, M., Ruiter, M., Vismara, R., Mastrullo, V., Agrifoglio, M., Zanobini, M., Pesce, M., Soncini, M. & Fiore, G. B., Oct 17 2016, (Accepted/In press) In : Annals of Biomedical Engineering. p. 1-14 14 p.

Research output: Contribution to journalArticle

Hemodynamics
Flow rate
Cell death
Bioreactors
Grafts

Human Saphenous Vein Response to Trans-wall Oxygen Gradients in a Novel Ex Vivo Conditioning Platform

Piola, M., Prandi, F., Fiore, G. B., Agrifoglio, M., Polvani, G., Pesce, M. & Soncini, M., May 2016, In : Annals of Biomedical Engineering. 44, 5, p. 1449-61 13 p.

Research output: Contribution to journalArticle

Oxygen
Grafts
Oxygenators
Blood
Networks (circuits)

On-chip assessment of human primary cardiac fibroblasts proliferative responses to uniaxial cyclic mechanical strain

Ugolini, G. S., Rasponi, M., Pavesi, A., Santoro, R., Kamm, R., Fiore, G. B., Pesce, M. & Soncini, M., Apr 1 2016, In : Biotechnology and Bioengineering. 113, 4, p. 859-869 11 p.

Research output: Contribution to journalArticle

Fibroblasts
Cell Nucleus Shape
Histones
Cues
Fluorescent Antibody Technique
2015

Abnormal megakaryopoiesis and platelet function in cyclooxygenase-2-deficient mice

Barbieri, S. S., Petrucci, G., Tarantino, E., Amadio, P., Rocca, B., Pesce, M., Machlus, K. R., Ranelletti, F. O., Gianellini, S., Weksler, B. B., Italiano, J. E. & Tremoli, E., 2015, In : Thrombosis and Haemostasis. 114, 6, p. 1218-1229 12 p.

Research output: Contribution to journalArticle

Cyclooxygenase 2
Blood Platelets
Megakaryocytes
Spleen
Bone Marrow

Adventitial vessel growth and progenitor cells activation in an ex vivo culture system mimicking human saphenous vein wall strain after coronary artery bypass grafting

Prandi, F., Piola, M., Soncini, M., Colussi, C., D'Alessandra, Y., Penza, E., Agrifoglio, M., Vinci, M. C., Polvani, G., Gaetano, C., Fiore, G. B. & Pesce, M., Feb 17 2015, In : PLoS One. 10, 2, e0117409.

Research output: Contribution to journalArticle

saphenous vein
Adventitia
Saphenous Vein
coronary vessels
Coronary Artery Bypass

A lumped-parameter approach for designing a novel pulsatile bioreactor for ex-vivo studies of human saphenous vein remodeling

Piola, M., Soncini, M., Pesce, M. & Fiore, G. B., Nov 4 2015, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. Institute of Electrical and Electronics Engineers Inc., Vol. 2015-November. p. 2588-2591 4 p. 7318921

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Saphenous Vein
Bioreactors
Coronary Artery Bypass
Pulsatile Flow
Pulsatile flow

Epigenetic Profile of Human Adventitial Progenitor Cells Correlates With Therapeutic Outcomes in a Mouse Model of Limb Ischemia

Gubernator, M., Slater, S. C., Spencer, H. L., Spiteri, I., Sottoriva, A., Riu, F., Rowlinson, J., Avolio, E., Katare, R., Mangialardi, G., Oikawa, A., Reni, C., Campagnolo, P., Spinetti, G., Touloumis, A., Tavaré, S., Prandi, F., Pesce, M., Hofner, M., Klemens, V. & 3 others, Emanueli, C., Angelini, G. & Madeddu, P., Jan 8 2015, (Accepted/In press) In : Arteriosclerosis, Thrombosis, and Vascular Biology.

Research output: Contribution to journalArticle

Adventitia
Saphenous Vein
Epigenomics
Stem Cells
Ischemia

Human Saphenous Vein Response to Trans-wall Oxygen Gradients in a Novel Ex Vivo Conditioning Platform

Piola, M., Prandi, F., Fiore, G. B., Agrifoglio, M., Polvani, G., Pesce, M. & Soncini, M., Aug 29 2015, (Accepted/In press) In : Annals of Biomedical Engineering.

Research output: Contribution to journalArticle

Oxygen
Grafts
Oxygenators
Blood
Networks (circuits)
Antigen-Presenting Cells
Cytokines
Genomics
Lymphocytes
Phenotype
2014

Expression of dual Nucleotides/Cysteinyl-Leukotrienes Receptor GPR17 in early trafficking of cardiac stromal cells after myocardial infarction

Cosentino, S., Castiglioni, L., Colazzo, F., Nobili, E., Tremoli, E., Rosa, P., Abbracchio, M. P., Sironi, L. & Pesce, M., Sep 1 2014, In : Journal of Cellular and Molecular Medicine. 18, 9, p. 1785-1796 12 p.

Research output: Contribution to journalArticle

Stromal Cells
Nucleotides
Myocardial Infarction
Stem Cells
Uracil Nucleotides
2013

Epigenetic Programming and Risk: The Birthplace of Cardiovascular Disease?

Vinci, M. C., Polvani, G. & Pesce, M., Jun 2013, In : Stem Cell Reviews and Reports. 9, 3, p. 241-253 13 p.

Research output: Contribution to journalArticle

Epigenomics
Cardiovascular Diseases
Embryonic Development
Histone Code
Physiological Phenomena

Growth induction and low-oxygen apoptosis inhibition of human CD34 + progenitors in collagen gels

Avitabile, D., Salchert, K., Werner, C., Capogrossi, M. C. & Pesce, M., 2013, In : BioMed Research International. 2013, 542810.

Research output: Contribution to journalArticle

Stem cells
Collagen
Stem Cells
Gels
Apoptosis

Mechanical Compliance and Immunological Compatibility of Fixative-Free Decellularized/Cryopreserved Human Pericardium

Vinci, M. C., Tessitore, G., Castiglioni, L., Prandi, F., Soncini, M., Santoro, R., Consolo, F., Colazzo, F., Micheli, B., Sironi, L., Polvani, G. & Pesce, M., May 21 2013, In : PLoS One. 8, 5, e64769.

Research output: Contribution to journalArticle

pericardium
Fixatives
Pericardium
compliance
Compliance
2012
Cell Engineering
Tissue Engineering
Stem Cells
Bioengineering
Cost of Illness

Patient profile modulates cardiac c-kit+ progenitor cell availability and amplification potential

Gambini, E., Pesce, M., Persico, L., Bassetti, B., Gambini, A., Alamanni, F., Agrifoglio, M., Capogrossi, M. C. & Pompilio, G., Nov 2012, In : Translational Research. 160, 5, p. 363-373 11 p.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-kit
Amplification
Stem Cells
Fluorescence
Availability
Tissue Engineering
Blood Vessels
Veins
Transplants
Bioengineering
2011

Cardiac stem cells: Tales, mysteries and promises in heart generation and regeneration

Pesce, M., Pompilio, G., Gambini, E. & Capogrossi, M. C., 2011, Regenerative Medicine: From Protocol to Patient. Springer Netherlands, p. 265-286 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Regeneration
Stem Cells
Muscle Cells
Publications
Myocardium

C-kit+ cardiac progenitors exhibit mesenchymal markers and preferential cardiovascular commitment

Gambini, E., Pompilio, G., Biondi, A., Alamanni, F., Capogrossi, M. C., Agrifoglio, M. & Pesce, M., Feb 1 2011, In : Cardiovascular Research. 89, 2, p. 362-373 12 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Stem Cells
Smooth Muscle Myocytes
Population
Osteoblasts

Endothelial and cardiac progenitors: Boosting, conditioning and (re)programming for cardiovascular repair

Pesce, M., Burba, I., Gambini, E., Prandi, F., Pompilio, G. & Capogrossi, M. C., Jan 2011, In : Pharmacology and Therapeutics. 129, 1, p. 50-61 12 p.

Research output: Contribution to journalArticle

Stem Cells
Adult Stem Cells
Muscle Cells
Myocardial Ischemia
Blood Vessels

Endothelial fate and angiogenic properties of human CD34 + progenitor cells in zebrafish

Pozzoli, O., Vella, P., Iaffaldano, G., Parente, V., Devanna, P., Lacovich, M., Lamia, C. L., Fascio, U., Longoni, D., Cotelli, F., Capogrossi, M. C. & Pesce, M., Jul 2011, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 31, 7, p. 1589-1597 9 p.

Research output: Contribution to journalArticle

Zebrafish
Blood Vessels
Stem Cells
Fetal Blood
Amputation

Histone deacetylase inhibition enhances self renewal and cardioprotection by human cord blood-derived CD34 + cells

Burba, I., Colombo, G. I., Staszewsky, L. I., de Simone, M., Devanna, P., Nanni, S., Avitabile, D., Molla, F., Cosentino, S., Russo, I., de Angelis, N., Soldo, A., Biondi, A., Gambini, E., Gaetano, C., Farsetti, A., Pompilio, G., Latini, R., Capogrossi, M. C. & Pesce, M., 2011, In : PLoS One. 6, 7, e22158.

Research output: Contribution to journalArticle

histone deacetylase
Histone Deacetylases
Fetal Blood
Repair
Blood

Human cord blood CD34+ progenitor cells acquire functional cardiac properties through a cell fusion process

Avitabile, D., Crespi, A., Brioschi, C., Parente, V., Toietta, G., Devanna, P., Baruscotti, M., Truffa, S., Scavone, A., Rusconi, F., Biondi, A., D'Alessandra, Y., Vigna, E., Difrancesco, D., Pesce, M., Capogrossi, M. C. & Barbuti, A., May 2011, In : American Journal of Physiology - Heart and Circulatory Physiology. 300, 5

Research output: Contribution to journalArticle

Cell Fusion
Fetal Blood
Stem Cells
Cardiac Myocytes
Muscle Cells
2010

Gene transfer into human cord blood-derived CD34+ cells by adeno-associated viral vectors

Schuhmann, N. K., Pozzoli, O., Sallach, J., Huber, A., Avitabile, D., Perabo, L., Rappl, G., Capogrossi, M. C., Hallek, M., Pesce, M. & Büning, H., Sep 2010, In : Experimental Hematology. 38, 9, p. 707-717 11 p.

Research output: Contribution to journalArticle

Fetal Blood
Genetic Engineering
Genes
Transgenes
Integrins

GMP-based CD133 + cells isolation maintains progenitor angiogenic properties and enhances standardization in cardiovascular cell therapy

Gaipa, G., Tilenni, M., Straino, S., Burba, I., Zaccagnini, G., Belotti, D., Biagi, E., Valentini, M., Perseghin, P., Parma, M., Campli, C. D., Biondi, A., Capogrossi, M. C., Pompilio, G. & Pesce, M., Jun 2010, In : Journal of Cellular and Molecular Medicine. 14, 6 B, p. 1619-1634 16 p.

Research output: Contribution to journalArticle

Cell Separation
Cell- and Tissue-Based Therapy
Hindlimb
Fetal Blood
Cardiomyopathies

Granulocyte colony-stimulating factor attenuates left ventricular remodelling after acute anterior STEMI: Results of the single-blind, randomized, placebo-controlled multicentre STem cEll Mobilization in Acute Myocardial Infarction (STEM-AMI) Trial

Achilli, F., Malafronte, C., Lenatti, L., Gentile, F., Dadone, V., Gibelli, G., Maggiolini, S., Squadroni, L., Di Leo, C., Burba, I., Pesce, M., Mircoli, L., Capogrossi, M. C., Di Lelio, A., Camisasca, P., Morabito, A., Colombo, G. & Pompilio, G., Oct 2010, In : European Journal of Heart Failure. 12, 10, p. 1111-1121 11 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cell Mobilization
Ventricular Remodeling
Granulocyte Colony-Stimulating Factor
Myocardial Infarction
Placebos

Magnetic resonance imaging of human endothelial progenitors reveals opposite effects on vascular and muscle regeneration into ischaemic tissues

Gianella, A., Guerrini, U., Tilenni, M., Sironi, L., Milano, G., Nobili, E., Vaga, S., Capogrossi, M. C., Tremoli, E. & Pesce, M., Feb 2010, In : Cardiovascular Research. 85, 3, p. 503-513 11 p.

Research output: Contribution to journalArticle

Blood Vessels
Regeneration
Magnetic Resonance Imaging
Muscles
Iron

When cells become a drug. Endothelial progenitor cells for cardiovascular therapy: Aims and reality

Burba, I., Devanna, P. & Pesce, M., Jan 2010, In : Recent Patents on Cardiovascular Drug Discovery. 5, 1, p. 1-10 10 p.

Research output: Contribution to journalArticle

Cell- and Tissue-Based Therapy
Stem Cells
Pharmaceutical Preparations
Regeneration
Pluripotent Stem Cells
2009

Altered SDF-1-mediated differentiation of bone marrow-derived endothelial progenitor cells in diabetes mellitus

De Falco, E., Avitabile, D., Totta, P., Straino, S., Spallotta, F., Cencioni, C., Torella, A. R., Rizzi, R., Porcelli, D., Zacheo, A., Vito, L. D., Pompilio, G., Napolitano, M., Melillo, G., Capogrossi, M. C. & Pesce, M., Sep 2009, In : Journal of Cellular and Molecular Medicine. 13, 9 B, p. 3405-3414 10 p.

Research output: Contribution to journalArticle

Chemokine CXCL12
Diabetes Mellitus
Bone Marrow
Ischemia
Hindlimb

Endothelial progenitor cells and cardiovascular homeostasis: Clinical implications

Pompilio, G., Capogrossi, M. C., Pesce, M., Alamanni, F., DiCampli, C., Achilli, F., Germani, A. & Biglioli, P., Jan 9 2009, In : International Journal of Cardiology. 131, 2, p. 156-167 12 p.

Research output: Contribution to journalArticle

Homeostasis
Atherosclerosis
Ischemia
Biomedical Engineering
Cell Transplantation
2008

Direct minimally invasive intramyocardial injection of bone marrow-derived AC133+ stem cells in patients with refractory ischemia: Preliminary results

Pompilio, G., Steinhoff, G., Liebold, A., Pesce, M., Alamanni, F., Capogrossi, M. C. & Biglioli, P., Mar 2008, In : Thoracic and Cardiovascular Surgeon. 56, 2, p. 71-76 6 p.

Research output: Contribution to journalArticle

Stem Cells
Ischemia
Single-Photon Emission-Computed Tomography
Bone Marrow
Injections