• 2934 Citations
  • 23 h-Index
20022018
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Fingerprint Dive into the research topics where Nicoletta Pedemonte is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 9 Similar Profiles
Cystic Fibrosis Transmembrane Conductance Regulator Medicine & Life Sciences
Cystic Fibrosis Medicine & Life Sciences
Chloride Channels Medicine & Life Sciences
Mutation Medicine & Life Sciences
Pharmacology Medicine & Life Sciences
Proteins Medicine & Life Sciences
Epithelial Cells Medicine & Life Sciences
Epithelium Medicine & Life Sciences

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Research Output 2002 2018

  • 2934 Citations
  • 23 h-Index
  • 48 Article
  • 1 Conference contribution
  • 1 Review article

Chemically modified hCFTR mRNAs recuperate lung function in a mouse model of cystic fibrosis

Haque, A. K. M. A., Dewerth, A., Antony, J. S., Riethmüller, J., Schweizer, G. R., Weinmann, P., Latifi, N., Yasar, H., Pedemonte, N., Sondo, E., Weidensee, B., Ralhan, A., Laval, J., Schlegel, P., Seitz, C., Loretz, B., Lehr, C-M., Handgretinger, R. & Kormann, M. S. D., Nov 13 2018, In : Scientific Reports. 8, 1, p. 16776

Research output: Contribution to journalArticle

Cystic Fibrosis
Nanoparticles
Lung
Messenger RNA
Viral DNA
6 Citations (Scopus)

High-throughput screening identifies FAU protein as a regulator of mutant cystic fibrosis transmembrane conductance regulator channel

Tomati, V., Pesce, E., Caci, E., Sondo, E., Scudieri, P., Marini, M., Amato, F., Castaldo, G., Ravazzolo, R., Galietta, L. J. V. & Pedemonte, N., Jan 1 2018, In : Journal of Biological Chemistry. 293, 4, p. 1203-1217 15 p.

Research output: Contribution to journalArticle

Cystic Fibrosis Transmembrane Conductance Regulator
Screening
Throughput
Proteins
Cell membranes

Pharmacological Inhibition of the Ubiquitin Ligase RNF5 Rescues F508del-CFTR in Cystic Fibrosis Airway Epithelia

Sondo, E., Falchi, F., Caci, E., Ferrera, L., Giacomini, E., Pesce, E., Tomati, V., Mandrup Bertozzi, S., Goldoni, L., Armirotti, A., Ravazzolo, R., Cavalli, A. & Pedemonte, N., Jul 19 2018, In : Cell Chemical Biology. 25, 7, p. 891-905.e8

Research output: Contribution to journalArticle

Ligases
Ubiquitin
Cystic Fibrosis
Epithelium
Pharmacology
9 Citations (Scopus)

Synthesis and biological evaluation of novel thiazole- VX-809 hybrid derivatives as F508del correctors by QSAR-based filtering tools

Liessi, N., Cichero, E., Pesce, E., Arkel, M., Salis, A., Tomati, V., Paccagnella, M., Damonte, G., Tasso, B., Galietta, L. J. V., Pedemonte, N., Fossa, P. & Millo, E., Jan 20 2018, In : European Journal of Medicinal Chemistry. 144, p. 179-200 22 p.

Research output: Contribution to journalArticle

Thiazoles
Quantitative Structure-Activity Relationship
Derivatives
Cystic Fibrosis Transmembrane Conductance Regulator
Molecules

The Autophagy Inhibitor Spautin-1 Antagonizes Rescue of Mutant CFTR Through an Autophagy-Independent and USP13-Mediated Mechanism

Pesce, E., Sondo, E., Ferrera, L., Tomati, V., Caci, E., Scudieri, P., Musante, I., Renda, M., Baatallah, N., Servel, N., Hinzpeter, A., di Bernardo, D., Pedemonte, N. & Galietta, L. J. V., 2018, In : Frontiers in Pharmacology. 9, p. 1464

Research output: Contribution to journalArticle

Autophagy
Cystic Fibrosis
Biological Phenomena
Chloride Channels
Quality Control