1980 …2019

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2019

Poly(I:C) stimulation is superior than Imiquimod to induce the antitumoral functional profile of tumor-conditioned macrophages

Maeda, A., Digifico, E., Andon, F. T., Mantovani, A. & Allavena, P., May 2019, In : European Journal of Immunology. 49, 5, p. 801-811 11 p.

Research output: Contribution to journalArticle

Open Access
2018

Cells with stemness features are generated from in vitro transformed human fibroblasts

Bono, B., Ostano, P., Peritore, M., Gregnanin, I., Belgiovine, C., Liguori, M., Allavena, P., Chiorino, G., Chiodi, I. & Mondello, C., Dec 1 2018, In : Scientific Reports. 8, 1, 13838.

Research output: Contribution to journalArticle

Differential role of Interleukin-1 and Interleukin-6 in K-Ras-driven pancreatic carcinoma undergoing mesenchymal transition

Siddiqui, I., Erreni, M., Kamal, M. A., Porta, C., Marchesi, F., Pesce, S., Pasqualini, F., Schiarea, S., Chiabrando, C., Mantovani, A. & Allavena, P., Feb 1 2018, In : OncoImmunology. 7, 2, e1388485.

Research output: Contribution to journalArticle

Evaluation of mediators associated with the inflammatory response in prostate cancer patients undergoing radiotherapy

Bedini, N., Cicchetti, A., Palorini, F., Magnani, T., Zuco, V., Pennati, M., Campi, E., Allavena, P., Pesce, S., Villa, S., Avuzzi, B., Morlino, S., Visentin, M. E., Zaffaroni, N., Rancati, T. & Valdagni, R., 2018, In : Disease Markers. 2018

Research output: Contribution to journalArticle

Evaluation of mediators associated with the inflammatory response in prostate cancer patients undergoing radiotherapy

Bedini, N., Cicchetti, A., Palorini, F., Magnani, T., Zuco, V., Pennati, M., Campi, E., Allavena, P., Pesce, S., Villa, S., Avuzzi, B., Morlino, S., Visentin, M. E., Zaffaroni, N., Rancati, T. & Valdagni, R., Jan 1 2018, In : Disease Markers. 2018, 9128128.

Research output: Contribution to journalArticle

FAM49B, a novel regulator of mitochondrial function and integrity that suppresses tumor metastasis

Chattaragada, M. S., Riganti, C., Sassoe, M., Principe, M., Santamorena, M. M., Roux, C., Curcio, C., Evangelista, A., Allavena, P., Salvia, R., Rusev, B., Scarpa, A., Cappello, P. & Novelli, F., Feb 8 2018, In : Oncogene. 37, 6, p. 697-709 13 p.

Research output: Contribution to journalArticle

Soluble stroma-related biomarkers of pancreatic cancer

Resovi, A., Bani, M. R., Porcu, L., Anastasia, A., Minoli, L., Allavena, P., Cappello, P., Novelli, F., Scarpa, A., Morandi, E., Falanga, A., Torri, V., Taraboletti, G., Belotti, D. & Giavazzi, R., Aug 2018, In : EMBO Molecular Medicine. 10, 8

Research output: Contribution to journalArticle

2017

Antitumour activity of trabectedin in myelodysplastic/myeloproliferative neoplasms

Romano, M., Della Porta, M. G., Gallì, A., Panini, N., Licandro, S. A., Bello, E., Craparotta, I., Rosti, V., Bonetti, E., Tancredi, R., Rossi, M., Mannarino, L., Marchini, S., Porcu, L., Galmarini, C. M., Zambelli, A., Zecca, M., Locatelli, F., Cazzola, M., Biondi, A. & 4 others, Rambaldi, A., Allavena, P., Erba, E. & D'Incalci, M., Jan 1 2017, In : British Journal of Cancer. 116, 3, p. 335-343 9 p.

Research output: Contribution to journalArticle

Antitumour activity of trabectedin in myelodysplastic/myeloproliferative neoplasms

Romano, M., Della Porta, M. G., Gallì, A., Panini, N., Licandro, S. A., Bello, E., Craparotta, I., Rosti, V., Bonetti, E., Tancredi, R., Rossi, M., Mannarino, L., Marchini, S., Porcu, L., Galmarini, C. M., Zambelli, A., Zecca, M., Locatelli, F., Cazzola, M., Biondi, A. & 4 others, Rambaldi, A., Allavena, P., Erba, E. & D'Incalci, M., Jan 2017, In : British Journal of Cancer. 116, 3, p. 335-343 9 p.

Research output: Contribution to journalArticle

Antitumour activity of trabectedin in myelodysplastic/myeloproliferative neoplasms

Romano, M., Della Porta, M. G., Gallì, A., Panini, N., Licandro, S. A., Bello, E., Craparotta, I., Rosti, V., Bonetti, E., Tancredi, R., Rossi, M., Mannarino, L., Marchini, S., Porcu, L., Galmarini, C. M., Zambelli, A., Zecca, M., Locatelli, F., Cazzola, M., Biondi, A. & 4 others, Rambaldi, A., Allavena, P., Erba, E. & D'Incalci, M., Jan 2017, In : British Journal of Cancer. 116, 3, p. 335-343 9 p.

Research output: Contribution to journalArticle

Antitumour activity of trabectedin in myelodysplastic/myeloproliferative neoplasms

Romano, M., Della Porta, M. G., Gallì, A., Panini, N., Licandro, S. A., Bello, E., Craparotta, I., Rosti, V., Bonetti, E., Tancredi, R., Rossi, M., Mannarino, L., Marchini, S., Porcu, L., Galmarini, C. M., Zambelli, A., Zecca, M., Locatelli, F., Cazzola, M., Biondi, A. & 4 others, Rambaldi, A., Allavena, P., Erba, E. & D'Incalci, M., 2017, In : British Journal of Cancer. 116, 3, p. 335-343 9 p.

Research output: Contribution to journalArticle

Depletion of tumor-associated macrophages switches the epigenetic profile of pancreatic cancer infiltrating T cells and restores their anti-tumor phenotype

Borgoni, S., Iannello, A., Cutrupi, S., Allavena, P., D'Incalci, M., Novelli, F. & Cappello, P., 2017, In : OncoImmunology. 7, 2, p. e1393596

Research output: Contribution to journalArticle

Depletion of tumor-associated macrophages switches the epigenetic profile of pancreatic cancer infiltrating T cells and restores their anti-tumor phenotype

Borgoni, S., Iannello, A., Cutrupi, S., Allavena, P., D'Incalci, M., Novelli, F. & Cappello, P., 2017, In : OncoImmunology. 7, 2, p. e1393596

Research output: Contribution to journalArticle

Heme-oxygenase-1 production by intestinal CX3CR1+ macrophages helps to resolve inflammation and prevents carcinogenesis

Marelli, G., Erreni, M., Anselmo, A., Taverniti, V., Guglielmetti, S., Mantovani, A. & Allavena, P., Aug 15 2017, In : Cancer Research. 77, 16, p. 4472-4485 14 p.

Research output: Contribution to journalArticle

Lurbinectedin reduces tumour-associated macrophages and the inflammatory tumour microenvironment in preclinical models

Belgiovine, C., Bello, E., Liguori, M., Craparotta, I., Mannarino, L., Paracchini, L., Beltrame, L., Marchini, S., Galmarini, C. M., Mantovani, A., Frapolli, R., Allavena, P. & D'Incalci, M., Aug 22 2017, In : British Journal of Cancer. 117, 5, p. 628-638 11 p.

Research output: Contribution to journalArticle

Lurbinectedin reduces tumour-associated macrophages and the inflammatory tumour microenvironment in preclinical models

Belgiovine, C., Bello, E., Liguori, M., Craparotta, I., Mannarino, L., Paracchini, L., Beltrame, L., Marchini, S., Galmarini, C. M., Mantovani, A., Frapolli, R., Allavena, P. & D'Incalci, M., Aug 22 2017, In : British Journal of Cancer. 117, 5, p. 628-638 11 p.

Research output: Contribution to journalArticle

2016

Circulating inflammatory mediators as potential prognostic markers of human colorectal cancer

Di Caro, G., Carvello, M., Pesce, S. A., Erreni, M., Marchesi, F., Todoric, J., Sacchi, M., Montorsi, M., Allavena, P. & Spinelli, A., Feb 1 2016, In : PLoS One. 11, 2, e0148186.

Research output: Contribution to journalArticle

Functional TRAIL receptors in monocytes and tumor-associated macrophages: A possible targeting pathway in the tumor microenvironment

Liguori, M., Buracchi, C., Pasqualini, F., Bergomas, F., Pesce, S. A., Sironi, M., Grizzi, F., Mantovani, A., Belgiovine, C. & Allavena, P., Jul 5 2016, In : Oncotarget. 7, 27, p. 41662-41676 15 p.

Research output: Contribution to journalArticle

Lurbinectedin induces depletion of tumor-associated macrophages, an essential component of its in vivo synergism with gemcitabine, in pancreatic adenocarcinoma mouse models

Céspedes, M. V., Guillén, M. J., López-Casas, P. P., Sarno, F., Gallardo, A., Álamo, P., Cuevas, C., Hidalgo, M., Galmarini, C. M., Allavena, P., Avilés, P. & Mangues, R., Dec 1 2016, In : DMM Disease Models and Mechanisms. 9, 12, p. 1461-1471 11 p.

Research output: Contribution to journalArticle

Phase II trial of salvage therapy with trabectedin in metastatic pancreatic adenocarcinoma

Belli, C., Piemonti, L., D'Incalci, M., Zucchetti, M., Porcu, L., Cappio, S., Doglioni, C., Allavena, P., Ceraulo, D., Maggiora, P., Dugnani, E., Cangi, M. G., Garassini, G. & Reni, M., Mar 1 2016, In : Cancer Chemotherapy and Pharmacology. 77, 3, p. 477-484 8 p.

Research output: Contribution to journalArticle

Phase II trial of salvage therapy with trabectedin in metastatic pancreatic adenocarcinoma

Belli, C., Piemonti, L., D'Incalci, M., Zucchetti, M., Porcu, L., Cappio, S., Doglioni, C., Allavena, P., Ceraulo, D., Maggiora, P., Dugnani, E., Cangi, M., Garassini, G. & Reni, M., Mar 1 2016, In : Cancer Chemotherapy and Pharmacology. 77, 3, p. 477-484 8 p.

Research output: Contribution to journalArticle

Phase II trial of salvage therapy with trabectedin in metastatic pancreatic adenocarcinoma

Belli, C., Piemonti, L., D'Incalci, M., Zucchetti, M., Porcu, L., Cappio, S., Doglioni, C., Allavena, P., Ceraulo, D., Maggiora, P., Dugnani, E., Cangi, M., Garassini, G. & Reni, M., Mar 1 2016, In : Cancer Chemotherapy and Pharmacology. 77, 3, p. 477-484 8 p.

Research output: Contribution to journalArticle

Prognostic and diagnostic potential of local and circulating levels of pentraxin 3 in lung cancer patients

Infante, M., Allavena, P., Garlanda, C., Nebuloni, M., Morenghi, E., Rahal, D., Roncalli, M., Cavuto, S., Pesce, S., Monari, M., Valaperta, S., Montanelli, A., Solomon, D., Bottoni, E., Errico, V., Voulaz, E., Bossi, M., Chiesa, G., Passera, E., Mantovani, A. & 1 others, Alloisio, M., Feb 15 2016, In : International Journal of Cancer. 138, 4, p. 983-991 9 p.

Research output: Contribution to journalArticle

Prognostic and diagnostic potential of local and circulating levels of pentraxin 3 in lung cancer patients

Infante, M., Allavena, P., Garlanda, C., Nebuloni, M., Morenghi, E., Rahal, D., Roncalli, M., Cavuto, S., Pesce, S. A., Monari, M. N., Valaperta, S., Montanelli, A., Solomon, D., Bottoni, E., Errico, V., Voulaz, E., Bossi, M., Chiesa, F. G., Passera, E., Mantovani, A. & 1 others, Alloisio, M., Feb 15 2016, In : International Journal of Cancer. 138, 4, p. 983-991 9 p.

Research output: Contribution to journalArticle

Prognostic and diagnostic potential of local and circulating levels of pentraxin 3 in lung cancer patients

Infante, M., Allavena, P., Garlanda, C., Nebuloni, M., Morenghi, E., Rahal, D., Roncalli, M., Cavuto, S., Pesce, S. A., Monari, M. N., Valaperta, S., Montanelli, A., Solomon, D., Bottoni, E., Errico, V., Voulaz, E., Bossi, M., Chiesa, F. G., Passera, E., Mantovani, A. & 1 others, Alloisio, M., Feb 15 2016, In : International Journal of Cancer. 138, 4, p. 983-991 9 p.

Research output: Contribution to journalArticle

Prognostic and diagnostic potential of local and circulating levels of pentraxin 3 in lung cancer patients

Infante, M., Allavena, P., Garlanda, C., Nebuloni, M., Morenghi, E., Rahal, D., Roncalli, M., Cavuto, S., Pesce, S. A., Monari, M. N., Valaperta, S., Montanelli, A., Solomon, D., Bottoni, E., Errico, V., Voulaz, E., Bossi, M., Chiesa, F. G., Passera, E., Mantovani, A. & 1 others, Alloisio, M., Feb 15 2016, In : International Journal of Cancer. 138, 4, p. 983-991 9 p.

Research output: Contribution to journalArticle

Spatial distribution of B cells predicts prognosis in human pancreatic adenocarcinoma

Castino, G. F., Cortese, N., Capretti, G., Serio, S., Di Caro, G., Mineri, R., Magrini, E., Grizzi, F., Cappello, P., Novelli, F., Spaggiari, P., Roncalli, M., Ridolfi, C., Gavazzi, F., Zerbi, A., Allavena, P. & Marchesi, F., Apr 2 2016, In : OncoImmunology. 5, 4

Research output: Contribution to journalArticle

Spatial distribution of B cells predicts prognosis in human pancreatic adenocarcinoma

Castino, G. F., Cortese, N., Capretti, G., Serio, S., Di Caro, G., Mineri, R., Magrini, E., Grizzi, F., Cappello, P., Novelli, F., Spaggiari, P., Roncalli, M., Ridolfi, C., Gavazzi, F., Zerbi, A., Allavena, P. & Marchesi, F., Apr 2 2016, In : OncoImmunology. 5, 4

Research output: Contribution to journalArticle

The fractalkine-receptor axis improves human colorectal cancer prognosis by limiting tumor metastatic dissemination

Erreni, M., Siddiqui, I., Marelli, G., Grizzi, F., Bianchi, P., Morone, D., Marchesi, F., Celesti, G., Pesce, S., Doni, A., Rumio, C., Roncalli, M. G., Laghi, L., Mantovani, A. & Allavena, P., Jan 15 2016, In : Journal of Immunology. 196, 2, p. 902-914 13 p.

Research output: Contribution to journalArticle

Tumor-associated macrophages and anti-tumor therapies: complex links

Belgiovine, C., D’Incalci, M., Allavena, P. & Frapolli, R., Mar 8 2016, (Accepted/In press) In : Cellular and Molecular Life Sciences. p. 1-14 14 p.

Research output: Contribution to journalArticle

2015

Dual prognostic significance of tumour-associated macrophages in human pancreatic adenocarcinoma treated or untreated with chemotherapy

Caro, G. D., Cortese, N., Castino, G. F., Grizzi, F., Gavazzi, F., Ridolfi, C., Capretti, G., Mineri, R., Todoric, J., Zerbi, A., Allavena, P., Mantovani, A. & Marchesi, F., Jul 8 2015, (Accepted/In press) In : Gut.

Research output: Contribution to journalArticle

Erratum: Intestinal immune homeostasis is regulated by the crosstalk between epithelial cells and dendritic cells (Nature Immunology (2005) 6 (507-514))

Rimoldi, M., Chieppa, M., Salucci, V., Avogadri, F., Sonzogni, A., Sampietro, G. M., Nespoli, A., Viale, G., Allavena, P. & Rescigno, M., Feb 17 2015, In : Nature Immunology. 16, 3, p. 326 1 p.

Research output: Contribution to journalArticle

Macrophage polarization in pathology

Sica, A., Erreni, M., Allavena, P. & Porta, C., Jul 26 2015, In : Cellular and Molecular Life Sciences. 72, 21, p. 4111-4126 16 p.

Research output: Contribution to journalArticle

The interaction of anticancer therapies with tumor-associated macrophages

Mantovani, A. & Allavena, P., 2015, In : Journal of Experimental Medicine. 212, 4, p. 435-445 11 p.

Research output: Contribution to journalArticle

2014

Pharmacological modulation of monocytes and macrophages

Mantovani, A., Vecchi, A. & Allavena, P., 2014, In : Current Opinion in Pharmacology. 17, 1, p. 38-44 7 p.

Research output: Contribution to journalArticle

Trabectedin, a drug acting on both cancer cells and the tumour microenvironment

D'Incalci, M., Badri, N., Galmarini, C. M. & Allavena, P., Aug 12 2014, In : British Journal of Cancer. 111, 4, p. 646-650 5 p.

Research output: Contribution to journalArticle

Trabectedin and plitidepsin: Drugs from the sea that strike the tumor microenvironment

Galmarini, C. M., D'Incalci, M. & Allavena, P., Feb 2014, In : Marine Drugs. 12, 2, p. 719-733 15 p.

Research output: Contribution to journalArticle

2013

Comparison of in vitro and in vivo biological effects of trabectedin, lurbinectedin (PM01183) and Zalypsis® (PM00104)

Romano, M., Frapolli, R., Zangarini, M., Bello, E., Porcu, L., Galmarini, C. M., García-Fernández, L. F., Cuevas, C., Allavena, P., Erba, E. & D'Incalci, M., Nov 2013, In : International Journal of Cancer. 133, 9, p. 2024-2033 10 p.

Research output: Contribution to journalArticle

Early expression of the fractalkine receptor CX3CR1 in pancreatic carcinogenesis

Celesti, G., Di Caro, G., Bianchi, P., Grizzi, F., Marchesi, F., Basso, G., Rahal, D., Delconte, G., Catalano, M., Cappello, P., Roncalli, M., Zerbi, A., Montorsi, M., Novelli, F., Mantovani, A., Allavena, P., Malesci, A. & Laghi, L., Oct 29 2013, In : British Journal of Cancer. 109, 9, p. 2424-2433 10 p.

Research output: Contribution to journalArticle