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Research Output 1990 2019

2019

An open-label, multicentre safety study of vemurafenib in patients with BRAFV600-mutant metastatic melanoma: final analysis and a validated prognostic scoring system

Larkin, J., Brown, M. P., Arance, A. M., Hauschild, A., Queirolo, P., Vecchio, M. D., Ascierto, P. A., Krajsová, I., Schachter, J., Neyns, B., Garbe, C., Sileni, V. C., Mandalà, M., Gogas, H., Espinosa, E., Hospers, G., Lorigan, P., Nyakas, M., Guminski, A., Liszkay, G. & 5 others, Rutkowski, P., Miller, W., Donica, M., Makrutzki, M. & Blank, C., Jan 2019, In : European Journal of Cancer. 107, p. 175-185 11 p.

Research output: Contribution to journalArticle

Multicenter Studies
Melanoma
Safety
Mutation
PLX4032
2 Citations (Scopus)

An open-label, multicentre safety study of vemurafenib in patients with BRAFV600-mutant metastatic melanoma: final analysis and a validated prognostic scoring system

Larkin, J., Brown, M. P., Arance, A. M., Hauschild, A., Queirolo, P., Vecchio, M. D., Ascierto, P. A., Krajsová, I., Schachter, J., Neyns, B., Garbe, C., Sileni, V. C., Mandalà, M., Gogas, H., Espinosa, E., Hospers, G., Lorigan, P., Nyakas, M., Guminski, A., Liszkay, G. & 5 others, Rutkowski, P., Miller, W., Donica, M., Makrutzki, M. & Blank, C., Jan 1 2019, In : European Journal of Cancer. 107, p. 175-185 11 p.

Research output: Contribution to journalArticle

Multicenter Studies
Melanoma
Safety
Mutation
PLX4032
1 Citation (Scopus)

Biomarker results from a phase II study of MEK1/2 inhibitor binimetinib (MEK162) in patients with advanced NRAS- or BRAF-mutated melanoma

Van Herpen, C. M. L., Agarwala, S. S., Hauschild, A., Berking, C., Thaddeus Beck, J., Schadendorf, D., Jansen, R., Queirolo, P., Ascierto, P. A., Blank, C. U., Heinrich, M. C., Pal, R. R., Derti, A., Antona, V., Nauwelaerts, H., Zubel, A. & Dummer, R., Mar 1 2019, In : Oncotarget. 10, 19, p. 1850-1859 10 p.

Research output: Contribution to journalArticle

Melanoma
Biomarkers
Mitogen-Activated Protein Kinases
Mitogen-Activated Protein Kinase Kinases
Mutation

Dabrafenib, trametinib and pembrolizumab or placebo in BRAF-mutant melanoma

Ascierto, P. A., Ferrucci, P. F., Fisher, R., Del Vecchio, M., Atkinson, V., Schmidt, H., Schachter, J., Queirolo, P., Long, G. V., Di Giacomo, A. M., Svane, I. M., Lotem, M., Bar-Sela, G., Couture, F., Mookerjee, B., Ghori, R., Ibrahim, N., Moreno, B. H. & Ribas, A., Jun 1 2019, In : Nature Medicine. 25, 6, p. 941-946 6 p.

Research output: Contribution to journalLetter

Melanoma
Placebos
Blocking Antibodies
Mitogen-Activated Protein Kinase Kinases
Transaminases

Dietary compounds and cutaneous malignant melanoma: Recent advances from a biological perspective

The Italian Melanoma Intergroup (IMI), May 21 2019, In : Nutrition and Metabolism. 16, 1, 33.

Research output: Contribution to journalArticle

Open Access
Melanoma
Cutaneous Malignant Melanoma
Incidence
Research
Therapeutics

Effectiveness of dabrafenib in the treatment of patients with BRAF V600-mutated metastatic melanoma in a Named Patient Program

Martin-Algarra, S., Hinshelwood, R., Mesnage, S., Cebon, J., Ferrucci, P. F., Aglietta, M., Neyns, B., Chiarion-Sileni, V., Lindsay, C. R., Del Vecchio, M., Linardou, H., Merelli, B., Tonini, G., Atkinson, V., Freivogel, K., Stein, D., Dalland, L., Lau, M., Legenne, P., Queirolo, P. & 1 others, Millward, M., 2019, In : Melanoma Research. 29, 5, p. 527-532 6 p.

Research output: Contribution to journalArticle

Melanoma
Confidence Intervals
Therapeutics
Disease-Free Survival
Fever
2 Citations (Scopus)

Germline and somatic mutations in patients with multiple primary melanomas: A next generation sequencing study

Casula, M., Paliogiannis, P., Ayala, F., De Giorgi, V., Stanganelli, I., Mandalà, M., Colombino, M., Manca, A., Sini, M. C., Caracò, C., Ascierto, P. A., Satta, R. R., Dedola, M. F., Denti, S., Fedeli, M. A., Montesu, M. A., Profili, S., Scotto, T., Sini, G., Tanda, F. & 9 others, Lissia, A., Cossu, A., Palmieri, G., Ghiorzo, P., Queirolo, P., Quaglino, P., Botti, G., Sileni, V. C. & Di Giacomo, A. M., Aug 5 2019, In : BMC Cancer. 19, 1, 772.

Research output: Contribution to journalArticle

Open Access
Germ-Line Mutation
Melanoma
Mutation
Italy
Population

HO-1 downregulation favors BRAFV600 melanoma cell death induced by Vemurafenib/PLX4032 and increases NK recognition

Furfaro, A. L., Ottonello, S., Loi, G., Cossu, I., Piras, S., Spagnolo, F., Queirolo, P., Marinari, U. M., Moretta, L., Pronzato, M. A., Mingari, M. C., Pietra, G. & Nitti, M., Jan 1 2019, (Accepted/In press) In : International Journal of Cancer.

Research output: Contribution to journalArticle

Heme Oxygenase-1
Melanoma
Cell Death
Down-Regulation
Natural Killer Cells

Identification and management of immune checkpoint inhibitor–related myocarditis: Use troponin wisely

Spallarossa, P., Tini, G., Sarocchi, M., Arboscello, E., Grossi, F., Queirolo, P., Zoppoli, G. & Ameri, P., Sep 1 2019, In : Journal of Clinical Oncology. 37, 25, p. 2201-2205 5 p.

Research output: Contribution to journalComment/debate

Identification and management of immune checkpoint inhibitor–related myocarditis: Use troponin wisely

Spallarossa, P., Tini, G., Sarocchi, M., Arboscello, E., Grossi, F., Queirolo, P., Zoppoli, G. & Ameri, P., 2019, In : Journal of Clinical Oncology. 37, 25, p. 2201-2205 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Immune-checkpoint inhibitors for the treatment of metastatic melanoma: a model of cancer immunotherapy

Queirolo, P., Boutros, A., Tanda, E., Spagnolo, F. & Quaglino, P., Jan 1 2019, In : Seminars in Cancer Biology.

Research output: Contribution to journalReview article

Immunotherapy
Melanoma
Neoplasms
Therapeutics
Standard of Care

Mutational concordance between primary and metastatic melanoma: A next-generation sequencing approach

Manca, A., Paliogiannis, P., Colombino, M., Casula, M., Lissia, A., Botti, G., Caracò, C., Ascierto, P. A., Sini, M. C., Palomba, G., Pisano, M., Dedola, M. F., Fedeli, M. A., Montesu, M. A., Rubino, C., Satta, R., Scotto, T., Sini, G., Maio, M., Massi, D. & 10 others, Anichini, A., Pfeffer, U., Doneddu, V., Cossu, A., Palmieri, G., Ghiorzo, P., Queirolo, P., Quaglino, P., Sileni, V. C. & Di Giacomo, A. M., 2019, In : Journal of Translational Medicine. 17, 1

Research output: Contribution to journalArticle

Melanoma
Genes
Tissue
Mutation
Literature
Tissue Distribution
Melanoma
Catenins
Myeloid Cells
Immunity
2018

CDKN2A germline mutations are not associated with poor survival in an Italian cohort of melanoma patients

Dalmasso, B., Pastorino, L., Ciccarese, G., Andreotti, V., Grillo, F., Mastracci, L., Spagnolo, F., Ballestrero, A., Queirolo, P., Bruno, W. & Ghiorzo, P., Jan 1 2018, (Accepted/In press) In : Journal of the American Academy of Dermatology.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinase Inhibitor p16
Germ-Line Mutation
Melanoma
Survival
Genes
1 Citation (Scopus)

Combining molecular and immunohistochemical analyses of key drivers in primary melanomas: Interplay between germline and somatic variations

William, B., Claudia, M., Bruna, D., Virginia, A., Lorenza, P., Francesco, C., Marina, G., Francesco, S., Alberto, B., Paola, Q., Federica, G., Luca, M. & Paola, G., Jan 1 2018, In : Oncotarget. 9, 5, p. 5691-5702 12 p.

Research output: Contribution to journalArticle

Melanoma
Mutation
Germ-Line Mutation
Carcinogenesis
Mutation Rate
15 Citations (Scopus)

Comprehensive Study of the Clinical Phenotype of Germline BAP1 Variant-Carrying Families Worldwide

Walpole, S., Pritchard, A. L., Cebulla, C. M., Pilarski, R., Stautberg, M., Davidorf, F. H., de la Fouchardière, A., Cabaret, O., Golmard, L., Stoppa-Lyonnet, D., Garfield, E., Njauw, C. N., Cheung, M., Turunen, J. A., Repo, P., Järvinen, R. S., van Doorn, R., Jager, M. J., Luyten, G. P. M., Marinkovic, M. & 57 others, Chau, C., Potrony, M., Höiom, V., Helgadottir, H., Pastorino, L., Bruno, W., Andreotti, V., Dalmasso, B., Ciccarese, G., Queirolo, P., Mastracci, L., Wadt, K., Kiilgaard, J. F., Speicher, M. R., van Poppelen, N., Kilic, E., Al-Jamal, R. T., Dianzani, I., Betti, M., Bergmann, C., Santagata, S., Dahiya, S., Taibjee, S., Burke, J., Poplawski, N., O'Shea, S. J., Newton-Bishop, J., Adlard, J., Adams, D. J., Lane, A. M., Kim, I., Klebe, S., Racher, H., Harbour, J. W., Nickerson, M. L., Murali, R., Palmer, J. M., Howlie, M., Symmons, J., Hamilton, H., Warrier, S., Glasson, W., Johansson, P., Robles-Espinoza, C. D., Ossio, R., de Klein, A., Puig, S., Ghiorzo, P., Nielsen, M., Kivelä, T. T., Tsao, H., Testa, J. R., Gerami, P., Stern, M. H., Paillerets, B. B. D., Abdel-Rahman, M. H. & Hayward, N. K., Dec 1 2018, In : Journal of the National Cancer Institute. 110, 12, p. 1328-1341 14 p.

Research output: Contribution to journalArticle

BRCA1 Protein
Phenotype
Neoplasms
Mesothelioma
Age of Onset

Correction: Combining molecular and immunohistochemical analyses of key drivers in primary melanomas: Interplay between germline and somatic variations [Oncotarget. 2018; 9:5691-5702]doi 10.18632/oncotarget.23204

Bruno, W., Martinuzzi, C., Dalmasso, B., Andreotti, V., Pastorino, L., Cabiddu, F., Gualco, M., Spagnolo, F., Ballestrero, A., Queirolo, P., Grillo, F., Mastracci, L. & Ghiorzo, P., Jun 19 2018, In : Oncotarget. 9, 47, p. 28798 1 p.

Research output: Contribution to journalComment/debate

Skin Neoplasms
Italy
Melanoma
Skin
Multivariate Analysis

Correction to: Clinicopathological predictors of recurrence in nodular and superficial spreading cutaneous melanoma: a multivariate analysis of 214 cases

Italian Melanoma Intergroup (IMI), Magi, S. & Mazzoni, L., Feb 20 2018, In : Journal of Translational Medicine. 16, 1, p. 33

Research output: Contribution to journalArticle

Skin Neoplasms
Italy
Melanoma
Skin
Multivariate Analysis
1 Citation (Scopus)
Conflict of Interest
Melanoma
Survival
Italy
Genes
3 Citations (Scopus)

CTLA-4 gene variant -1661A>G may predict the onset of endocrine adverse events in metastatic melanoma patients treated with ipilimumab

Italian Melanoma Intergroup (IMI), Jul 1 2018, In : European Journal of Cancer. 97, p. 59-61 3 p.

Research output: Contribution to journalLetter

CTLA-4 gene variant -1661A>G may predict the onset of endocrine adverse events in metastatic melanoma patients treated with ipilimumab

Queirolo, P., Dozin, B., Morabito, A., Banelli, B., Carosio, R., Fontana, V., Ferrucci, P. F., Martinoli, C., Cocorocchio, E., Ascierto, P. A., Madonna, G., Simeone, E., De Galitiis, F., Antonini Cappellini, G. C., Marchetti, P., Guida, M., Tommasi, S., Ghilardi, L., Merelli, B., Fava, P. & 7 others, Osella-Abate, S., Guidoboni, M., Romani, M., Ferone, D., Spagnolo, F., Pistillo, M. P. & (IMI), I. M. I., 2018, In : European journal of cancer. 97, p. 59-61 3 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Current status and perspectives in immunotherapy for metastatic melanoma

Marconcini, R., Spagnolo, F., Stucci, L. S., Ribero, S., Marra, E., de Rosa, F. D., Picasso, V., di Guardo, L. D., Cimminiello, C., Cavalieri, S., Orgiano, L., Tanda, E., Spano, L., Falcone, A., Queirolo, P., Palmieri, G., Stanganelli, I., Mandalà, M., Quaglino, P., Botti, G. & 3 others, Caracò, C., Sileni, V. C. & di Giacomo, A. M., Jan 1 2018, In : Oncotarget. 9, 15, p. 12452-12470 19 p.

Research output: Contribution to journalArticle

Immunotherapy
Melanoma
Immune System Diseases
Drug Combinations
Pharmaceutical Preparations

Current status and perspectives in immunotherapy for metastatic melanoma

Marconcini, R., Spagnolo, F., Stucci, L. S., Ribero, S., Marra, E., de Rosa, F. D., Picasso, V., di Guardo, L. D., Cimminiello, C., Cavalieri, S., Orgiano, L., Tanda, E., Spano, L., Falcone, A., Queirolo, P., Palmieri, G., Stanganelli, I., Mandalà, M., Quaglino, P., Botti, G. & 3 others, Caracò, C., Sileni, V. C. & di Giacomo, A. M., 2018, In : Oncotarget. 9, 15, p. 12452-12470 19 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Effect of age on melanoma risk, prognosis and treatment response

Italian Melanoma Intergroup (IMI), Jan 1 2018, In : Acta Dermato-Venereologica. 98, 7, p. 624-629 6 p.

Research output: Contribution to journalReview article

Melanoma
Therapeutics
Survival
Nevus
Nevi and Melanomas
3 Citations (Scopus)

Efficacy of novel immunotherapy regimens in patients with metastatic melanoma with germline CDKN2A mutations

Helgadottir, H., Ghiorzo, P., Van Doorn, R., Puig, S., Levin, M., Kefford, R., Lauss, M., Queirolo, P., Pastorino, L., Kapiteijn, E., Potrony, M., Carrera, C., Olsson, H., Höiom, V. & Jönsson, G., Jan 1 2018, (Accepted/In press) In : Journal of Medical Genetics.

Research output: Contribution to journalArticle

Germ-Line Mutation
Immunotherapy
Melanoma
Mutation
Tumor Burden
2 Citations (Scopus)

Prognostic impact of regression in patients with primary cutaneous melanoma >1 mm in thickness

Italian Melanoma Intergroup, Jan 1 2018, (Accepted/In press) In : Journal of the American Academy of Dermatology.

Research output: Contribution to journalArticle

Melanoma
Sentinel Lymph Node Biopsy
Skin
Confidence Intervals
Survival
5 Citations (Scopus)

Soluble CTLA-4 as a favorable predictive biomarker in metastatic melanoma patients treated with ipilimumab: an Italian melanoma intergroup study

on behalf of the Italian Melanoma Intergroup (IMI), Jan 1 2018, (Accepted/In press) In : Cancer Immunology, Immunotherapy.

Research output: Contribution to journalArticle

Melanoma
Biomarkers
ipilimumab
Survival Analysis
Serum

Vitamin D in melanoma: Controversies and potential role in combination with immune check-point inhibitors

Italian Melanoma Intergroup (IMI), Sep 2018, In : Cancer Treatment Reviews. 69, p. 21-28 8 p.

Research output: Contribution to journalReview article

Vitamin D
Melanoma
Vitamin D Deficiency
Immune System Diseases
Up-Regulation
6 Citations (Scopus)

Vitamin D in melanoma: Controversies and potential role in combination with immune check-point inhibitors

for the Italian Melanoma Intergroup (IMI), Sep 1 2018, In : Cancer Treatment Reviews. 69, p. 21-28 8 p.

Research output: Contribution to journalReview article

Vitamin D
Melanoma
Vitamin D Deficiency
Immune System Diseases
Up-Regulation

Vitamin D in melanoma: Controversies and potential role in combination with immune check-point inhibitors

Stucci, L. S., D'Oronzo, S., Tucci, M., Macerollo, A., Ribero, S., Spagnolo, F., Marra, E., Picasso, V., Orgiano, L., Marconcini, R., De Rosa, F., Guardo, L. D., Galli, G., Gandini, S., Palmirotta, R., Palmieri, G., Queirolo, P., Silvestris, F. & (IMI), F. T. I. M. I., 2018, In : Cancer Treatment Reviews. 69, p. 21-28 8 p.

Research output: Contribution to journalArticle

Vitamin D
Melanoma
Vitamin D Deficiency
Immune System Diseases
Up-Regulation

Vitamin D in melanoma: Controversies and potential role in combination with immune check-point inhibitors

Stucci, L. S., D'Oronzo, S., Tucci, M., Macerollo, A., Ribero, S., Spagnolo, F., Marra, E., Picasso, V., Orgiano, L., Marconcini, R., De Rosa, F., Guardo, L. D., Galli, G., Gandini, S., Palmirotta, R., Palmieri, G., Queirolo, P., Silvestris, F. & (IMI), F. T. I. M. I., 2018, In : Cancer Treatment Reviews. 69, p. 21-28 8 p.

Research output: Contribution to journalArticle

2017
466 Citations (Scopus)

Adjuvant nivolumab versus ipilimumab in resected stage III or IV melanoma

Weber, J., Mandala, M., Del Vecchio, M., Gogas, H. J., Arance, A. M., Cowey, C. L., Dalle, S., Schenker, M., Chiarion-Sileni, V., Marquez-Rodas, I., Grob, J-J., Butler, M. O., Middleton, M. R., Maio, M., Atkinson, V., Queirolo, P., Gonzalez, R., Kudchadkar, R. R., Smylie, M., Meyer, N. & 14 others, Mortier, L., Atkins, M. B., Long, G. V., Bhatia, S., Lebbé, C., Rutkowski, P., Yokota, K., Yamazaki, N., Kim, T. M., De Pril, V., Sabater, J., Qureshi, A., Larkin, J. & Ascierto, P. A., Nov 9 2017, In : New England Journal of Medicine. 377, 19, p. 1824-1835 12 p.

Research output: Contribution to journalArticle

Melanoma
Recurrence
Confidence Intervals
Survival
Poisons
466 Citations (Scopus)

Adjuvant nivolumab versus ipilimumab in resected stage III or IV melanoma

Weber, J., Mandala, M., Del Vecchio, M., Gogas, H. J., Arance, A. M., Cowey, C. L., Dalle, S., Schenker, M., Chiarion-Sileni, V., Marquez-Rodas, I., Grob, J. J., Butler, M. O., Middleton, M. R., Maio, M., Atkinson, V., Queirolo, P., Gonzalez, R., Kudchadkar, R. R., Smylie, M., Meyer, N. & 15 others, Mortier, L., Atkins, M. B., Long, G. V., Bhatia, S., Lebbé, C., Rutkowski, P., Yokota, K., Yamazaki, N., Kim, T. M., De Pril, V., Sabater, J., Qureshi, A., Larkin, J., Ascierto, P. A. & for the CheckMate 238 Collaborators, Nov 9 2017, In : New England Journal of Medicine. 377, 19, p. 1824-1835 12 p.

Research output: Contribution to journalArticle

Melanoma
Recurrence
Poisons
Confidence Intervals
Therapeutics
466 Citations (Scopus)

Adjuvant nivolumab versus ipilimumab in resected stage III or IV melanoma

Weber, J., Mandala, M., Del Vecchio, M., Gogas, H. J., Arance, A. M., Cowey, C. L., Dalle, S., Schenker, M., Chiarion-Sileni, V., Marquez-Rodas, I., Grob, J-J., Butler, M. O., Middleton, M. R., Maio, M., Atkinson, V., Queirolo, P., Gonzalez, R., Kudchadkar, R. R., Smylie, M., Meyer, N. & 14 others, Mortier, L., Atkins, M. B., Long, G. V., Bhatia, S., Lebbé, C., Rutkowski, P., Yokota, K., Yamazaki, N., Kim, T. M., De Pril, V., Sabater, J., Qureshi, A., Larkin, J. & Ascierto, P. A., 2017, In : New England Journal of Medicine. 377, 19, p. 1824-1835 12 p.

Research output: Contribution to journalArticle

466 Citations (Scopus)

Adjuvant nivolumab versus ipilimumab in resected stage III or IV melanoma

Weber, J., Mandala, M., Del Vecchio, M., Gogas, H. J., Arance, A. M., Cowey, C. L., Dalle, S., Schenker, M., Chiarion-Sileni, V., Marquez-Rodas, I., Grob, J-J., Butler, M. O., Middleton, M. R., Maio, M., Atkinson, V., Queirolo, P., Gonzalez, R., Kudchadkar, R. R., Smylie, M., Meyer, N. & 15 others, Mortier, L., Atkins, M. B., Long, G. V., Bhatia, S., Lebbé, C., Rutkowski, P., Yokota, K., Yamazaki, N., Kim, T. M., De Pril, V., Sabater, J., Qureshi, A., Larkin, J., Ascierto, P. A. & Guidoboni, M., 2017, In : New England Journal of Medicine. 377, 19, p. 1824-1835 12 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Association of CTLA-4 Gene Variants with Response to Therapy and Long-term Survival in Metastatic Melanoma Patients Treated with Ipilimumab: An Italian Melanoma Intergroup Study

Queirolo, P., Dozin, B., Morabito, A., Banelli, B., Piccioli, P., Fava, C., Leo, C., Carosio, R., Laurent, S., Fontana, V., Ferrucci, P. F., Martinoli, C., Cocorocchio, E., Battaglia, A., Ascierto, P. A., Capone, M., Simeone, E., De Galitiis, F., Pagani, E., Antonini Cappellini, G. C. & 11 others, Marchetti, P., Guida, M., Tommasi, S., Mandalà, M., Merelli, B., Quaglino, P., Fava, P., Guidoboni, M., Romani, M., Spagnolo, F. & Pistillo, M. P., 2017, In : Frontiers in Immunology. 8, p. 386

Research output: Contribution to journalArticle

Melanoma
Nucleotides
Survival
Genes
Genotype
6 Citations (Scopus)

Association of CTLA-4 gene variants with response to therapy and long-term survival in metastatic melanoma patients treated with ipilimumab: An Italian melanoma intergroup study

Queirolo, P., Dozin, B., Morabito, A., Banelli, B., Piccioli, P., Fava, C., Leo, C., Carosio, R., Laurent, S., Fontana, V., Ferrucci, P. F., Martinoli, C., Cocorocchio, E., Battaglia, A., Ascierto, P. A., Capone, M., Simeone, E., De Galitiis, F., Pagani, E., Cappellini, G. C. A. & 11 others, Marchetti, P., Guida, M., Tommasi, S., Mandalà, M., Merelli, B., Quaglino, P., Fava, P., Guidoboni, M., Romani, M., Spagnolo, F. & Pistillo, M. P., 2017, In : Frontiers in Immunology. 8, APR

Research output: Contribution to journalArticle

Melanoma
Nucleotides
Survival
Genes
Genotype
6 Citations (Scopus)

Association of CTLA-4 gene variants with response to therapy and long-term survival in metastatic melanoma patients treated with ipilimumab: An Italian melanoma intergroup study

Queirolo, P., Dozin, B., Morabito, A., Banelli, B., Piccioli, P., Fava, C., Leo, C., Carosio, R., Laurent, S., Fontana, V., Ferrucci, P. F., Martinoli, C., Cocorocchio, E., Battaglia, A., Ascierto, P. A., Capone, M., Simeone, E., De Galitiis, F., Pagani, E., Cappellini, G. C. A. & 11 others, Marchetti, P., Guida, M., Tommasi, S., Mandalà, M., Merelli, B., Quaglino, P., Fava, P., Guidoboni, M., Romani, M., Spagnolo, F. & Pistillo, M. P., 2017, In : Frontiers in Immunology. 8, APR

Research output: Contribution to journalArticle

16 Citations (Scopus)
Death Domain Receptors
Renal Cell Carcinoma
Melanoma
Lung Neoplasms
Pharmaceutical Preparations
8 Citations (Scopus)

Binimetinib for the treatment of NRAS-mutant melanoma

Queirolo, P. & Spagnolo, F., Nov 2 2017, In : Expert Review of Anticancer Therapy. 17, 11, p. 985-990 6 p.

Research output: Contribution to journalArticle

Melanoma
Mitogen-Activated Protein Kinase Kinases
Mutation
Immunotherapy
Therapeutics
111 Citations (Scopus)

Binimetinib versus dacarbazine in patients with advanced NRAS-mutant melanoma (NEMO): a multicentre, open-label, randomised, phase 3 trial

Dummer, R., Schadendorf, D., Ascierto, P. A., Arance, A., Dutriaux, C., Di Giacomo, A. M., Rutkowski, P., Del Vecchio, M., Gutzmer, R., Mandala, M., Thomas, L., Demidov, L., Garbe, C., Hogg, D., Liszkay, G., Queirolo, P., Wasserman, E., Ford, J., Weill, M., Sirulnik, L. A. & 4 others, Jehl, V., Bozón, V., Long, G. V. & Flaherty, K., Apr 2017, In : The Lancet Oncology. 18, 4, p. 435-445 11 p.

Research output: Contribution to journalArticle

Dacarbazine
Melanoma
Immunotherapy
Disease-Free Survival
Safety
111 Citations (Scopus)

Binimetinib versus dacarbazine in patients with advanced NRAS-mutant melanoma (NEMO): a multicentre, open-label, randomised, phase 3 trial

Dummer, R., Schadendorf, D., Ascierto, P. A., Arance, A., Dutriaux, C., Di Giacomo, A. M., Rutkowski, P., Del Vecchio, M., Gutzmer, R., Mandala, M., Thomas, L., Demidov, L., Garbe, C., Hogg, D., Liszkay, G., Queirolo, P., Wasserman, E., Ford, J., Weill, M., Sirulnik, L. A. & 4 others, Jehl, V., Bozón, V., Long, G. V. & Flaherty, K., 2017, In : The Lancet Oncology. 18, 4, p. 435-445 11 p.

Research output: Contribution to journalArticle

Dacarbazine
Melanoma
Immunotherapy
Disease-Free Survival
Safety
13 Citations (Scopus)

BRAF plus MEK-targeted drugs: a new standard of treatment for BRAF-mutant advanced melanoma

Queirolo, P. & Spagnolo, F., Mar 1 2017, In : Cancer and Metastasis Reviews. 36, 1, p. 35-42 8 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase Kinases
Melanoma
Pharmaceutical Preparations
Translational Medical Research
Therapeutics
3 Citations (Scopus)

Clinicopathological predictors of recurrence in nodular and superficial spreading cutaneous melanoma: A multivariate analysis of 214 cases

Pizzichetta, M. A., Massi, D., Mandalà, M., Queirolo, P., Stanganelli, I., De Giorgi, V., Ghigliotti, G., Cavicchini, S., Quaglino, P., Corradin, M. T., Rubegni, P., Alaibac, M., Astorino, S., Ayala, F., Magi, S., Mazzoni, L., Manganoni, M. A., Talamini, R., Serraino, D., Palmieri, G. & 1 others, on behalf of the Italian Melanoma Intergroup (IMI), Nov 7 2017, In : Journal of Translational Medicine. 15, 1, 227.

Research output: Contribution to journalArticle

Melanoma
Multivariate Analysis
Biopsy
Recurrence
Skin
3 Citations (Scopus)

Clinicopathological predictors of recurrence in nodular and superficial spreading cutaneous melanoma: a multivariate analysis of 214 cases

Pizzichetta, M. A., Massi, D., Mandalà, M., Queirolo, P., Stanganelli, I., De Giorgi, V., Ghigliotti, G., Cavicchini, S., Quaglino, P., Corradin, M. T., Rubegni, P., Alaibac, M., Astorino, S., Ayala, F., Magi, S., Mazzoni, L., Manganoni, M. A., Talamini, R., Serraino, D., Palmieri, G. & 1 others, Italian Melanoma Intergroup (IMI), Nov 7 2017, In : Journal of Translational Medicine. 15, 1, p. 227

Research output: Contribution to journalArticle

Melanoma
Multivariate Analysis
Biopsy
Recurrence
Skin

Clinicopathological predictors of recurrence in nodular and superficial spreading cutaneous melanoma: A multivariate analysis of 214 cases

Pizzichetta, M. A., Massi, D., Mandalà, M., Queirolo, P., Stanganelli, I., De Giorgi, V., Ghigliotti, G., Cavicchini, S., Quaglino, P., Corradin, M. T., Rubegni, P., Alaibac, M., Astorino, S., Ayala, F., Magi, S., Mazzoni, L., Manganoni, M. A., Talamini, R., Serraino, D. & Palmieri, G., 2017, In : Journal of Translational Medicine. 15, 1

Research output: Contribution to journalArticle

3 Citations (Scopus)

Clinicopathological predictors of recurrence in nodular and superficial spreading cutaneous melanoma: A multivariate analysis of 214 cases

Pizzichetta, M. A., Massi, D., Mandalà, M., Queirolo, P., Stanganelli, I., De Giorgi, V., Ghigliotti, G., Cavicchini, S., Quaglino, P., Corradin, M. T., Rubegni, P., Alaibac, M., Astorino, S., Ayala, F., Magi, S., Mazzoni, L., Manganoni, M. A., Talamini, R., Serraino, D. & Palmieri, G., 2017, In : Journal of Translational Medicine. 15, 1

Research output: Contribution to journalArticle

3 Citations (Scopus)

Clinicopathological predictors of recurrence in nodular and superficial spreading cutaneous melanoma: A multivariate analysis of 214 cases

Pizzichetta, M. A., Massi, D., Mandalà, M., Queirolo, P., Stanganelli, I., De Giorgi, V., Ghigliotti, G., Cavicchini, S., Quaglino, P., Corradin, M. T., Rubegni, P., Alaibac, M., Astorino, S., Ayala, F., Magi, S., Mazzoni, L., Manganoni, M. A., Talamini, R., Serraino, D. & Palmieri, G., 2017, In : Journal of Translational Medicine. 15, 1, 7 p., 227.

Research output: Contribution to journalArticle

Melanoma
Multivariate Analysis
Biopsy
Recurrence
Skin