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Fingerprint Dive into the research topics where Paolo Michieli is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 28 Similar Profiles
Hepatocyte Growth Factor Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Growth Medicine & Life Sciences
Oncogenes Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
p53 Genes Medicine & Life Sciences
Mutation Medicine & Life Sciences
Antibodies Medicine & Life Sciences

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Research Output 1991 2017

Stroma-derived HGF drives metabolic adaptation of colorectal cancer to angiogenesis inhibitors

Mira, A., Morello, V., Céspedes, M. V., Perera, T., Comoglio, P. M., Mangues, R. & Michieli, P., Jan 1 2017, In : Oncotarget. 8, 24, p. 38193-38213 21 p.

Research output: Contribution to journalArticle

Angiogenesis Inhibitors
Hepatocyte Growth Factor
Colorectal Neoplasms

Dual anti-idiotypic purification of a novel, native-format biparatopic anti-MET antibody with improved in vitro and in vivo efficacy

Godar, M., Morello, V., Sadi, A., Hultberg, A., De Jonge, N., Basilico, C., Hanssens, V., Saunders, M., Lambrecht, B. N., El Khattabi, M., De Haard, H., Michieli, P. & Blanchetot, C., Aug 22 2016, In : Scientific Reports. 6, 31621.

Research output: Contribution to journalArticle

Anti-Idiotypic Antibodies
Bispecific Antibodies
Single-Domain Antibodies

Dual Constant Domain-Fab: A novel strategy to improve half-life and potency of a Met therapeutic antibody

Cignetto, S., Modica, C., Chiriaco, C., Fontani, L., Milla, P., Michieli, P., Comoglio, P. M. & Vigna, E., Jun 1 2016, In : Molecular Oncology. 10, 6, p. 938-948 11 p.

Research output: Contribution to journalArticle

Molecular Weight
Immunoglobulin Fab Fragments

Depleting MET-expressing tumor cells by ADCC provides a therapeutic advantage over inhibiting HGF/MET signaling

Hultberg, A., Morello, V., Huyghe, L., De Jonge, N., Blanchetot, C., Hanssens, V., De Boeck, G., Silence, K., Festjens, E., Heukers, R., Roux, B., Lamballe, F., Ginestier, C., Charafe-Jauffret, E., Maina, F., Brouckaert, P., Saunders, M., Thibault, A., Dreier, T., De Haard, H. & 1 others, Michieli, P., Aug 15 2015, In : Cancer Research. 75, 16, p. 3373-3383 11 p.

Research output: Contribution to journalArticle

Neoplasm Antibodies
Hepatocyte Growth Factor

ADAM17-Dependent c-MET-STAT3 Signaling Mediates Resistance to MEK Inhibitors in KRAS Mutant Colorectal Cancer

VanSchaeybroeck, S., Kalimutho, M., Dunne, P. D., Carson, R., Allen, W., Jithesh, P. V., Redmond, K. L., Sasazuki, T., Shirasawa, S., Blayney, J., Michieli, P., Fenning, C., Lenz, H. J., Lawler, M., Longley, D. B. & Johnston, P. G., Jun 26 2014, In : Cell Reports. 7, 6, p. 1940-1955 16 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase Kinases
Colorectal Neoplasms
Chemical activation
Systems Biology