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Research Output

2020

Resistin is associated with overall survival in non-small cell lung cancer patients during nivolumab treatment

Bonaventura, A., Grossi, F., Carbone, F., Vecchié, A., Minetti, S., Bardi, N., Elia, E., Ansaldo, A. M., Ferrara, D., Rijavec, E., Dal Bello, M. G., Rossi, G., Biello, F., Tagliamento, M., Alama, A., Coco, S., Spallarossa, P., Dallegri, F., Genova, C. & Montecucco, F., Jan 1 2020, (Accepted/In press) In : Clinical and Translational Oncology.

Research output: Contribution to journalArticle

2019

Arterial hypertension in cancer: The elephant in the room

Tini, G., Sarocchi, M., Tocci, G., Arboscello, E., Ghigliotti, G., Novo, G., Brunelli, C., Lenihan, D., Volpe, M. & Spallarossa, P., Apr 15 2019, In : International Journal of Cardiology. 281, p. 133-139 7 p.

Research output: Contribution to journalArticle

Baseline serum levels of osteopontin predict clinical response to treatment with nivolumab in patients with non-small cell lung cancer: Clinical and Experimental Metastasis

Carbone, F., Grossi, F., Bonaventura, A., Vecchié, A., Minetti, S., Bardi, N., Elia, E., Ansaldo, A. M., Ferrara, D., Rijavec, E., Dal Bello, M. G., Biello, F., Rossi, G., Tagliamento, M., Alama, A., Coco, S., Spallarossa, P., Dallegri, F., Genova, C. & Montecucco, F., 2019, In : Clin. Exp. Metastasis. 36, 5, p. 449-456 8 p.

Research output: Contribution to journalArticle

Baseline serum levels of osteopontin predict clinical response to treatment with nivolumab in patients with non-small cell lung cancer

Carbone, F., Grossi, F., Bonaventura, A., Vecchié, A., Minetti, S., Bardi, N., Elia, E., Ansaldo, A. M., Ferrara, D., Rijavec, E., Dal Bello, M. G., Biello, F., Rossi, G., Tagliamento, M., Alama, A., Coco, S., Spallarossa, P., Dallegri, F., Genova, C. & Montecucco, F., Oct 15 2019, In : Clinical and Experimental Metastasis. 36, 5, p. 449-456 8 p.

Research output: Contribution to journalArticle

How Cardio-Oncology is called to prove its maturity

Tini, G. & Spallarossa, P., Aug 1 2019, In : International Journal of Cardiology. 288, p. 130-131 2 p.

Research output: Contribution to journalEditorial

Identification and management of immune checkpoint inhibitor–related myocarditis: Use troponin wisely

Spallarossa, P., Tini, G., Sarocchi, M., Arboscello, E., Grossi, F., Queirolo, P., Zoppoli, G. & Ameri, P., Sep 1 2019, In : Journal of Clinical Oncology. 37, 25, p. 2201-2205 5 p.

Research output: Contribution to journalComment/debate

Identification and management of immune checkpoint inhibitor–related myocarditis: Use troponin wisely

Spallarossa, P., Tini, G., Sarocchi, M., Arboscello, E., Grossi, F., Queirolo, P., Zoppoli, G. & Ameri, P., 2019, In : Journal of Clinical Oncology. 37, 25, p. 2201-2205 5 p.

Research output: Contribution to journalArticle

Ivabradine in Cancer Treatment-Related Left Ventricular Dysfunction

Sarocchi, M., Arboscello, E., Ghigliotti, G., Murialdo, R., Bighin, C., Gualandi, F., Sicbaldi, V., Balbi, M., Brunelli, C. & Spallarossa, P., Jan 1 2019, In : Chemotherapy. p. 315-320 6 p.

Research output: Contribution to journalArticle

Serum PCSK9 levels at the second nivolumab cycle predict overall survival in elderly patients with NSCLC: a pilot study

Bonaventura, A., Grossi, F., Carbone, F., Vecchié, A., Minetti, S., Bardi, N., Elia, E., Ansaldo, A. M., Ferrara, D., Rijavec, E., Dal Bello, M. G., Rossi, G., Biello, F., Tagliamento, M., Alama, A., Coco, S., Spallarossa, P., Dallegri, F., Genova, C. & Montecucco, F., Jan 1 2019, In : Cancer Immunology, Immunotherapy. 68, 8, p. 1351-1358

Research output: Contribution to journalArticle

Serum PCSK9 levels at the second nivolumab cycle predict overall survival in elderly patients with NSCLC: a pilot study

Bonaventura, A., Grossi, F., Carbone, F., Vecchié, A., Minetti, S., Bardi, N., Elia, E., Ansaldo, A. M., Ferrara, D., Rijavec, E., Dal Bello, M. G., Rossi, G., Biello, F., Tagliamento, M., Alama, A., Coco, S., Spallarossa, P., Dallegri, F., Genova, C. & Montecucco, F., 2019, In : Cancer Immunology and Immunotherapy. 68, 8, p. 1351-1358 8 p.

Research output: Contribution to journalArticle

The Need for Cardiovascular Risk Factor Prevention in Cardio-Oncology

Tini, G., Sarocchi, M., Ameri, P., Arboscello, E. & Spallarossa, P., Apr 1 2019, In : JACC: Heart Failure. 7, 4, p. 367-368 2 p.

Research output: Contribution to journalLetter

2018

Antineoplastic drug-induced cardiotoxicity: A redox perspective

Varricchi, G., Ameri, P., Cadeddu, C., Ghigo, A., Madonna, R., Marone, G., Mercurio, V., Monte, I., Novo, G., Parrella, P., Pirozzi, F., Pecoraro, A., Spallarossa, P., Zito, C., Mercuro, G., Pagliaro, P. & Tocchetti, C. G., Mar 7 2018, In : Frontiers in Physiology. 9, MAR, 167.

Research output: Contribution to journalReview article

Open Access

Early Diastolic Dysfunction after Cancer Chemotherapy: Primary Endpoint Results of a Multicenter Cardio-Oncology Study

Calabrese, V., Menna, P., Annibali, O., Armento, G., Carpino, A., Cerchiara, E., Greco, C., Marchesi, F., Spallarossa, P., Toglia, G., Reggiardo, G. & Minotti, G., Feb 9 2018, (Accepted/In press) In : Chemotherapy. p. 55-63 9 p.

Research output: Contribution to journalArticle

Potential cardiac risk of immune-checkpoint blockade as anticancer treatment: What we know, what we do not know, and what we can do to prevent adverse effects

Spallarossa, P., Meliota, G., Brunelli, C., Arboscello, E., Ameri, P., Dessalvi, C. C., Grossi, F., Deidda, M., Mele, D., Sarocchi, M., Bellodi, A., Madonna, R. & Mercuro, G., Sep 1 2018, In : Medicinal Research Reviews. 38, 5, p. 1447-1468 22 p.

Research output: Contribution to journalReview article

Serial Troponin for Early Detection of Nivolumab Cardiotoxicity in Advanced Non-Small Cell Lung Cancer Patients

Sarocchi, M., Grossi, F., Arboscello, E., Bellodi, A., Genova, C., Dal Bello, M. G., Rijavec, E., Barletta, G., Rossi, G., Biello, F., Ghigliotti, G., Canepa, M., Mussap, M., Brunelli, C. & Spallarossa, P., Aug 1 2018, In : Oncologist. 23, 8, p. 936-942 7 p.

Research output: Contribution to journalArticle

2017

5-fluorouracil causes endothelial cell senescence: potential protective role of glucagon-like peptide 1

Altieri, P., Murialdo, R., Barisione, C., Lazzarini, E., Garibaldi, S., Fabbi, P., Ruggeri, C., Borile, S., Carbone, F., Armirotti, A., Canepa, M., Ballestrero, A., Brunelli, C., Montecucco, F., Ameri, P. & Spallarossa, P., Nov 1 2017, In : British Journal of Pharmacology. 174, 21, p. 3713-3726 14 p.

Research output: Contribution to journalArticle

Doxorubicin effect on myocardial metabolism as a prerequisite for subsequent development of cardiac toxicity: A translational 18F-FDG PET/CT observation

Bauckneht, M., Ferrarazzo, G., Fiz, F., Morbelli, S., Sarocchi, M., Pastorino, F., Ghidella, A., Pomposelli, E., Miglino, M., Ameri, P., Emionite, L., Ticconi, F., Arboscello, E., Buschiazzo, A., Massimelli, E. A., Fiordoro, S., Borra, A., Cossu, V., Bozzano, A., Ibatici, A. & 6 others, Ponzoni, M., Spallarossa, P., Gallamini, A., Bruzzi, P., Sambuceti, G. & Marini, C., Oct 1 2017, In : Journal of Nuclear Medicine. 58, 10, p. 1638-1645 8 p.

Research output: Contribution to journalArticle

From Molecular Mechanisms to Clinical Management of Antineoplastic Drug-Induced Cardiovascular Toxicity: A Translational Overview

Tocchetti, C. G., Cadeddu, C., Di Lisi, D., Femminò, S., Madonna, R., Mele, D., Monte, I., Novo, G., Penna, C., Pepe, A., Spallarossa, P., Varricchi, G., Zito, C., Pagliaro, P. & Mercuro, G., May 15 2017, In : Antioxidants and Redox Signaling.

Research output: Contribution to journalArticle

Identification, prevention and management of cardiovascular risk in chronic myeloid leukaemia patients candidate to ponatinib: an expert opinion

Breccia, M., Pregno, P., Spallarossa, P., Arboscello, E., Ciceri, F., Giorgi, M., Grossi, A., Mallardo, M., Nodari, S., Ottolini, S., Sala, C., Tortorella, G., Rosti, G., Pane, F., Minotti, G. & Baccarani, M., 2017, In : Annals of Hematology. 96, 4, p. 549-558 10 p.

Research output: Contribution to journalArticle

Potential cardiac risk of immune-checkpoint blockade as anticancer treatment: What we know, what we do not know, and what we can do to prevent adverse effects

Spallarossa, P., Meliota, G., Brunelli, C., Arboscello, E., Ameri, P., Dessalvi, C. C., Grossi, F., Deidda, M., Mele, D., Sarocchi, M., Bellodi, A., Madonna, R. & Mercuro, G., Dec 28 2017, In : Medicinal Research Reviews.

Research output: Contribution to journalReview article

2016

A recommended practical approach to the management of anthracycline-based chemotherapy cardiotoxicity: An opinion paper of the working group on drug cardiotoxicity and cardioprotection, Italian Society of Cardiology

Spallarossa, P., Maurea, N., Cadeddu, C., Madonna, R., Mele, D., Monte, I., Novo, G., Pagliaro, P., Pepe, A., Tocchetti, C. G., Zito, C. & Mercuro, G., May 1 2016, In : Journal of Cardiovascular Medicine. 17, p. S84-S92

Research output: Contribution to journalArticle

A recommended practical approach to the management of target therapy and angiogenesis inhibitors cardiotoxicity: An opinion paper of the working group on drug cardiotoxicity and cardioprotection, Italian Society of Cardiology

Maurea, N., Spallarossa, P., Cadeddu, C., Madonna, R., Mele, D., Monte, I., Novo, G., Pagliaro, P., Pepe, A., Tocchetti, C. G., Zito, C. & Mercuro, G., May 1 2016, In : Journal of Cardiovascular Medicine. 17, p. S93-S104

Research output: Contribution to journalArticle

Cardiac toxicity of trastuzumab in elderly patients with breast cancer

Denegri, A., Moccetti, T., Moccetti, M., Spallarossa, P., Brunelli, C. & Ameri, P., 2016, In : Journal of Geriatric Cardiology. 13, 4, p. 355-363 9 p.

Research output: Contribution to journalReview article

Current views on anthracycline cardiotoxicity

Mele, D., Nardozza, M., Spallarossa, P., Frassoldati, A., Tocchetti, C. G., Cadeddu, C., Madonna, R., Malagù, M., Ferrari, R. & Mercuro, G., Sep 1 2016, In : Heart Failure Reviews. 21, 5, p. 621-634 14 p.

Research output: Contribution to journalArticle

Identification, prevention and management of cardiovascular risk in chronic myeloid leukaemia patients candidate to ponatinib: an expert opinion

Breccia, M., Pregno, P., Spallarossa, P., Arboscello, E., Ciceri, F., Giorgi, M., Grossi, A., Mallardo, M., Nodari, S., Ottolini, S., Sala, C., Tortorella, G., Rosti, G., Pane, F., Minotti, G. & Baccarani, M., Sep 30 2016, In : Annals of Hematology. 96, 4, p. 549-558 10 p.

Research output: Contribution to journalArticle

Identification, prevention and management of cardiovascular risk in chronic myeloid leukaemia patients candidate to ponatinib: an expert opinion

Breccia, M., Pregno, P., Spallarossa, P., Arboscello, E., Ciceri, F., Giorgi, M., Grossi, A., Mallardo, M., Nodari, S., Ottolini, S., Sala, C., Tortorella, G., Rosti, G., Pane, F., Minotti, G. & Baccarani, M., 2016, In : Annals of Hematology.

Research output: Contribution to journalArticle

Modelling chemotherapy-induced cardiotoxicity by human pluripotent stem cells

Madonna, R., Cadeddu, C., Deidda, M., Spallarossa, P., Zito, C. & Mercuro, G., Jan 1 2016, In : Current Drug Targets. 17, 16

Research output: Contribution to journalReview article

Pathophysiology of anthracycline cardiotoxicity

Mele, D., Tocchetti, C. G., Pagliaro, P., Madonna, R., Novo, G., Pepe, A., Zito, C., Maurea, N. & Spallarossa, P., May 1 2016, In : Journal of Cardiovascular Medicine. 17, p. S3-S11

Research output: Contribution to journalArticle

Pathophysiology of cardiotoxicity from target therapy and angiogenesis inhibitors

Maurea, N., Coppola, C., Piscopo, G., Galletta, F., Riccio, G., Esposito, E., De Lorenzo, C., De Laurentiis, M., Spallarossa, P. & Mercuro, G., May 1 2016, In : Journal of Cardiovascular Medicine. 17, p. S19-S26

Research output: Contribution to journalArticle

Preventing antiblastic drug-related cardiomyopathy: Old and new therapeutic strategies

Cadeddu, C., Mercurio, V., Spallarossa, P., Nodari, S., Triggiani, M., Monte, I., Piras, R., Madonna, R., Pagliaro, P., Tocchetti, C. G. & Mercuro, G., May 1 2016, In : Journal of Cardiovascular Medicine. 17, p. S64-S75

Research output: Contribution to journalArticle

Proposal for a tailored stratification at baseline and monitoring of cardiovascular effects during follow-up in chronic phase chronic myeloid leukemia patients treated with nilotinib frontline

Breccia, M., Arboscello, E., Bellodi, A., Colafigli, G., Molica, M., Bergamaschi, M., Massaro, F., Quattrocchi, L., Sarocchi, M., Spallarossa, P. & Alimena, G., Nov 2016, In : Critical Reviews in Oncology/Hematology. 107, p. 190-198 9 p.

Research output: Contribution to journalArticle

2015

Improving the preclinical models for the study of chemotherapy-induced cardiotoxicity: a Position Paper of the Italian Working Group on Drug Cardiotoxicity and Cardioprotection

Madonna, R., Cadeddu, C., Deidda, M., Mele, D., Monte, I., Novo, G., Pagliaro, P., Pepe, A., Spallarossa, P., Tocchetti, C. G., Zito, C. & Mercuro, G., Sep 8 2015, In : Heart Failure Reviews. 20, 5, p. 621-631 11 p.

Research output: Contribution to journalArticle

2013

Enalapril and carvedilol for preventing chemotherapy-induced left ventricular systolic dysfunction

Spallarossa, P., Guerrini, M., Arboscello, E. & Sicbaldi, V., Dec 24 2013, In : Journal of the American College of Cardiology. 62, 25, p. 2451-2452 2 p.

Research output: Contribution to journalLetter

2012

Inhibition of Doxorubicin-Induced Senescence by PPARδ Activation Agonists in Cardiac Muscle Cells: Cooperation between PPARδ and Bcl6

Altieri, P., Spallarossa, P., Barisione, C., Garibaldi, S., Garuti, A., Fabbi, P., Ghigliotti, G. & Brunelli, C., Sep 25 2012, In : PLoS One. 7, 9, e46126.

Research output: Contribution to journalArticle