1985 …2019

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2019

Lentiviral gene therapy corrects platelet phenotype and function in patients with Wiskott-Aldrich syndrome

Sereni, L., Castiello, M. C., Di Silvestre, D., Della Valle, P., Brombin, C., Ferrua, F., Cicalese, M. P., Pozzi, L., Migliavacca, M., Bernardo, M. E., Pignata, C., Farah, R., Notarangelo, L. D., Marcus, N., Cattaneo, L., Spinelli, M., Giannelli, S., Bosticardo, M., van Rossem, K., D'Angelo, A. & 3 others, Aiuti, A., Mauri, P. & Villa, A., Sep 2019, In : Journal of Allergy and Clinical Immunology. 144, 3, p. 825-838 14 p.

Research output: Contribution to journalArticle

Open Access

Missense changes in the catalytic domain of coagulation factor X account for minimal function preventing a perinatal lethal condition

Ferrarese, M., Baroni, M., Della Valle, P., Spiga, I., Poloniato, A., D'Angelo, A., Pinotti, M., Bernardi, F. & Branchini, A., Jul 2019, In : Haemophilia. 25, 4, p. 685-692 8 p.

Research output: Contribution to journalArticle

2018

A novel allele variant of the SERPINF2 gene responsible for severe plasmin inhibitor (α2-antiplasmin) deficiency in an Italian patient

Viganò, S., D'Andrea, G., Della Valle, P., Santacroce, R., Margaglione, M. & D'Angelo, A., 2018, In : Thrombosis Research. 166, p. 60-62 3 p.

Research output: Contribution to journalArticle

Platelet activation is a preoperative risk factor for the development of thromboembolic complications in patients with continuous-flow left ventricular assist device

Consolo, F., Sferrazza, G., Motolone, G., Contri, R., Valerio, L., Lembo, R., Pozzi, L., Della Valle, P., De Bonis, M., Zangrillo, A., Fiore, GB., Redaelli, A., Slepian, MJ. & Pappalardo, F., 2018, In : European Journal of Heart Failure. 20, 4, p. 792-800 9 p.

Research output: Contribution to journalArticle

Platelet microparticles sustain autophagy-associated activation of neutrophils in systemic sclerosis

Maugeri, N., Capobianco, A., Rovere-Querini, P., Ramirez, GA., Tombetti, E., Della Valle, P., Monno, A., D'Alberti, V., Gasparri, AM., Franchini, S., D'Angelo, A., Bianchi, ME. & Manfredi, AA., 2018, In : Science Translational Medicine. 10, 451, eaao3089.

Research output: Contribution to journalArticle

Which Antiplatelet Therapy in Patients With Left Ventricular Assist Device and Aspirin Allergy?

Consolo, F., Pozzi, L., Sferrazza, G., Della Valle, P., D'Angelo, A., Slepian, MJ. & Pappalardo, F., 2018, In : Annals of Thoracic Surgery. 105, 2, p. e47-e49

Research output: Contribution to journalArticle

2016

Low-grade endotoxemia and clotting activation in the early phase of pneumonia

Cangemi, R., Della Valle, P., Calvieri, C., Taliani, G., Ferroni, P., Falcone, M., Carnevale, R., Bartimoccia, S., D'angelo, A. & Violi, F., 2016, (Accepted/In press) In : Respirology.

Research output: Contribution to journalArticle

Low-grade endotoxemia and clotting activation in the early phase of pneumonia

Cangemi, R., Della Valle, P., Calvieri, C., Taliani, G., Ferroni, P., Falcone, M., Carnevale, R., Bartimoccia, S., D'Angelo, A. & Violi, F., 2016, (Accepted/In press) In : Respirology.

Research output: Contribution to journalArticle

Low-grade endotoxemia and clotting activation in the early phase of pneumonia

Cangemi, R., Della Valle, P., Calvieri, C., Taliani, G., Ferroni, P., Falcone, M., Carnevale, R., Bartimoccia, S., D'Angelo, A. & Violi, F., Nov 1 2016, In : Respirology. 21, 8, p. 1465 - 1471 7 p.

Research output: Contribution to journalArticle

2015

Liver-directed lentiviral gene therapy in a dog model of hemophilia B

Cantore, A., Ranzani, M., Bartholomae, C. C., Volpin, M., Valle, P. D., Sanvito, F., Sergi, L. S., Gallina, P., Benedicenti, F., Bellinger, D., Raymer, R., Merricks, E., Bellintani, F., Martin, S., Doglioni, C., D'Angelo, A., Driessche, T. V., Chuah, M. K., Schmidt, M., Nichols, T. & 2 others, Montini, E. & Naldini, L., Mar 4 2015, In : Science Translational Medicine. 7, 277

Research output: Contribution to journalArticle

2014

Effects of various modes of mechanical ventilation in normal rats

Pecchiari, M., Monaco, A., Koutsoukou, A., Valle, P. D., Gentile, G. & D'Angelo, E., 2014, In : Anesthesiology. 120, 4, p. 943-950 8 p.

Research output: Contribution to journalArticle

2013

Human protein C concentrate in a patient with meningitis and bleeding as a complication of treatment with recombinant activated protein C

Colombo, S., Crivellari, M., Mucci, M., Plumari, V., Silvani, P., Della Valle, P., D'Angelo, A. & Zangrillo, A., 2013, In : Signa Vitae. 8, 1, p. 62-64 3 p.

Research output: Contribution to journalArticle

Liver gene therapy by lentiviral vectors reverses anti-factor IX pre-existing immunity in haemophilic mice

Annoni, A., Cantore, A., Della Valle, P., Goudy, K., Akbarpour, M., Russo, F., Bartolaccini, S., D'Angelo, A., Roncarolo, M. G. & Naldini, L., Nov 2013, In : EMBO Molecular Medicine. 5, 11, p. 1684-1697 14 p.

Research output: Contribution to journalArticle

Vitreomacular traction syndrome: A comparison of treatment with intravitreal plasmin enzyme vs spontaneous vitreous separation without treatment

Codenotti, M., Maestranzi, G., De Benedetto, U., Querques, G., Della Valle, P., Iuliano, L., Fogliato, G., D'Angelo, A. & Bandello, F., Jan 2013, In : Eye (London, England). 27, 1, p. 22-27 6 p.

Research output: Contribution to journalArticle

2012

Hyperfunctional coagulation factor IX improves the efficacy of gene therapy in hemophilic mice

Cantore, A., Nair, N., Della Valle, P., Di Matteo, M., Màtrai, J., Sanvito, F., Brombin, C., Di Serio, C., D'Angelo, A., Chuah, M., Naldini, L. & VandenDriessche, T., Nov 29 2012, In : Blood. 120, 23, p. 4517-4520 4 p.

Research output: Contribution to journalArticle

The protein C pathway and sepsis

Della Valle, P., Pavani, G. & D'Angelo, A., Mar 2012, In : Thrombosis Research. 129, 3, p. 296-300 5 p.

Research output: Contribution to journalArticle

2010

Maintaining end-expiratory transpulmonary pressure prevents worsening of ventilator-induced lung injury caused by chest wall constriction in surfactant-depleted rats

Loring, S. H., Pecchiari, M., Della Valle, P., Monaco, A., Gentile, G. & D'Angelo, E., Dec 2010, In : Critical Care Medicine. 38, 12, p. 2358-2364 7 p.

Research output: Contribution to journalArticle

2009

Human protein C zymogen concentrate in patients with severe sepsis and multiple organ failure after adult cardiac surgery

Crivellari, M., Valle, P. D., Landoni, G., Pappalardo, F., Gerli, C., Bignami, E., Marino, G., Zangrillo, A. & D'Angelo, A., Nov 2009, In : Intensive Care Medicine. 35, 11, p. 1959-1963 5 p.

Research output: Contribution to journalArticle

Il laboratorio di coagulazione nelle situazioni di emergenza

Translated title of the contribution: Coagulation laboratory in emergency clinical settingsPattarini, E., Fattorini, A., Sampietro, F., Della Valle, P., Crippa, L., Viganò, S. & D'Angelo, A., 2009, In : Rivista Italiana della Medicina di Laboratorio. 5, 2, p. 99-103 5 p.

Research output: Contribution to journalArticle

2008

Cytokine release, small airway injury, and parenchymal damage during mechanical ventilation in normal open-chest rats

D'Angelo, E., Koutsoukou, A., Della Valle, P., Gentile, G. & Pecchiari, M., Jan 2008, In : Journal of Applied Physiology. 104, 1, p. 41-49 9 p.

Research output: Contribution to journalArticle

The fall in exhaled nitric oxide with ventilation at low lung volumes in rabbits: An index of small airway injury

D'Angelo, E., Koulouris, N. G., Della Valle, P., Gentile, G. & Pecchiari, M., Feb 1 2008, In : Respiratory Physiology and Neurobiology. 160, 2, p. 215-223 9 p.

Research output: Contribution to journalArticle

2007

A microRNA-regulated lentiviral vector mediates stable correction of hemophilia B mice

Brown, B. D., Cantore, A., Annoni, A., Sergi, L. S., Lombardo, A., Della Valle, P., D'Angelo, A. & Naldini, L., Dec 15 2007, In : Blood. 110, 13, p. 4144-4152 9 p.

Research output: Contribution to journalArticle

Phosphorylcholine coating may limit thrombin formation during high-risk cardiac surgery: A randomized controlled trial

Pappalardo, F., Valle, P. D., Crescenzi, G., Corno, C., Franco, A., Torracca, L., Alfieri, O., Galli, L., Zangrillo, A. & D'Angelo, A., Mar 2006, In : Annals of Thoracic Surgery. 81, 3, p. 886-891 6 p.

Research output: Contribution to journalArticle

2005

Effects of mechanical ventilation at low lung volume on respiratory mechanics and nitric oxide exhalation in normal rabbits

D'Angelo, E., Pecchiari, M., Della Valle, P., Koutsoukou, A. & Milic-Emili, J., Aug 2005, In : Journal of Applied Physiology. 99, 2, p. 433-444 12 p.

Research output: Contribution to journalArticle

Intrasurgical plasmin enzyme in diabetic macular edema [2] (multiple letters)

Gandorfer, A., Kampik, A., Azzolini, C., D'Angelo, A., Maestranzi, G., Codenotti, M., Della Valle, P., Prati, M. & Brancato, R., Apr 2005, In : American Journal of Ophthalmology. 139, 5, p. 949-950 2 p.

Research output: Contribution to journalArticle

2004

Emostasi nei pazienti diabetici e uremici: Impatto del trapianto di rene e pancreas

Translated title of the contribution: Normalization of multiple haemostatic abnormalities in uremic type 1 diabetic patients after kidney-pancreas transplantationFiorina, P., Folli, F., Bifari, F., Ventre, M. B., Finzi, G., Mazzolari, G., Fedeli, C., Guzzi, V., Della Valle, P., Placidi, C., Belloni, D., Ferrero, E., Capella, C., D'Angelo, A. & Secchi, A., Jun 2004, In : Giornale Italiano di Diabetologia e Metabolismo. 24, 2, p. 43-50 8 p.

Research output: Contribution to journalArticle

Intrasurgical plasmin enzyme in diabetic macular edema

Azzolini, C., D'Angelo, A., Maestranzi, G., Codenotti, M., Della Valle, P., Prati, M. & Brancato, R., Oct 2004, In : American Journal of Ophthalmology. 138, 4, p. 560-566 7 p.

Research output: Contribution to journalArticle

La proteina C e la coagulazione nella sepsi

Translated title of the contribution: Protein C and coagulation in sepsisD'Angelo, A., Della Valle, P., Giudici, D. & D'Angelo, S. V., May 2004, In : Minerva Anestesiologica. 70, 5, p. 339-350 12 p.

Research output: Contribution to journalArticle

Normalization of multiple hemostatic abnormalities in uremic type 1 diabetic patients after kidney-pancreas transplantation

Fiorina, P., Folli, F., D'Angelo, A., Finzi, G., Pellegatta, F., Guzzi, V., Fedeli, C., Della Valle, P., Usellini, L., Placidi, C., Bifari, F., Belloni, D., Ferrero, E., Capella, C. & Secchi, A., Sep 2004, In : Diabetes. 53, 9, p. 2291-2300 10 p.

Research output: Contribution to journalArticle

2002

Plasma levels of endothelial protein C receptor respond to anticoagulant treatment

Stearns-Kurosawa, D. J., Swindle, K., D'Angelo, A., Della Valle, P., Fattorini, A., Caron, N., Grimaux, M., Woodhams, B. & Kurosawa, S., Jan 15 2002, In : Blood. 99, 2, p. 526-530 5 p.

Research output: Contribution to journalArticle

Relationship between international normalized ratio values, vitamin K-dependent clotting factor levels and in vivo prothrombin activation during the early and steady phases of oral anticoagulant treatment

D'Angelo, A., Della Valle, P., Crippa, L., Fattrorini, A., Pattarini, E. & Vigano' D'Angelo, S., Oct 2002, In : Haematologica. 87, 10, p. 1074-1080 7 p.

Research output: Contribution to journalArticle

2001

Activation of coagulation and fibrinolysis during coronary surgery: Onpump versus off-pump techniques

Casati, V., Gerli, C., Franco, A., Della Valle, P., Benussi, S., Alfieri, O., Torri, G. & D'Angelo, A., 2001, In : Anesthesiology. 95, 5, p. 1103-1109 7 p.

Research output: Contribution to journalArticle

1999

Interference of lupus anticoagulants in prothrombin time assays: Implications for selection of adequate methods to optimize the management of thrombosis in antiphospholipid-antibody syndrome

Della Valle, P., Crippa, L., Garlando, A. M., Pattarini, E., Safa, O., D'Angelo, S. V. & D'Angelo, A., Dec 1999, In : Haematologica. 84, 12, p. 1065-1074 10 p.

Research output: Contribution to journalArticle

1998

Monitoring warfarin therapy in patients with lupus anticoagulants [1] (multiple letters)

Manoharan, A., D'Angelo, A., Della Valle, P., Crippa, L., Moll, S. & Ortel, T. L., Mar 15 1998, In : Annals of Internal Medicine. 128, 6, p. 504-505 2 p.

Research output: Contribution to journalArticle

1996

Critical aspects in routine coagulation testing

D'Angelo, A., Della Valle, P., Crippa, L., Pattarini, E. & Vigano' D'Angelo, S., Oct 1996, In : Pure and Applied Chemistry. 68, 10, p. 1867-1871 5 p.

Research output: Contribution to journalArticle

Potential failure of the International Normalized Ratio (INR) System in the monitoring of oral anticoagulation in patients with lupus anticoagulants

Della Valle, P., Crippa, L., Safa, O., Tomassini, L., Pattarini, E., Vigano-D'Angelo, S., Sabbadini, M. G. & D'Angelo, A., 1996, In : Annales de Medecine Interne. 147, SUPPL. 1, p. 10-14 5 p.

Research output: Contribution to journalArticle

The effect of cigarette-smoking on cardiovascular risk factors: A study of monozygotic twins discordant for smoking

Calori, G., D'Angelo, A., Della Valle, P., Ruotolo, G., Ferini-Strambi, L., Giusti, C., Errera, A. & Gallus, G., Jan 1996, In : Thrombosis and Haemostasis. 75, 1, p. 14-18 5 p.

Research output: Contribution to journalArticle

1995

Autoimmune protein S deficiency: A disorder predisposing to thrombosis

D'Angelo, A., Mazzola, G., Bergmann, F., Safat, O., Della Valle, P. & Vigano D'Angelo, S., 1995, In : Haematologica. 80, 2 SUPPL., p. 114-121 8 p.

Research output: Contribution to journalArticle

Oral anticoagulants: Old drugs with a promising future

D'Angelo, A., Crippa, L., Agazzi, A., Della Valle, P., Anzalone, N., Garlando, A. M. & Vigano D'Angelo, S., 1995, In : Haematologica. 80, 2 SUPPL., p. 92-101 10 p.

Research output: Contribution to journalArticle

Variable interference of activated protein C resistance in the measurement of protein S activity by commercial assays

ViganóD'Angelo, S., Mazzola, G., Valle, P. D., Testa, S., Pattarini, E. & D'Angelo, A., Feb 15 1995, In : Thrombosis Research. 77, 4, p. 375-378 4 p.

Research output: Contribution to journalArticle

1994

Hypercoagulability and high lipoprotein(a) levels in patients with central retinal vein occlusion

Bandello, F., D'Angelo, S. V., Parlavecchia, M., Tavola, A., Della Valle, P., Brancato, R. & D'Angelo, A., 1994, In : Thrombosis and Haemostasis. 72, 1, p. 39-43 5 p.

Research output: Contribution to journalArticle

1993

Brief report: Autoimmune protein S deficiency in a boy with severe thromboembolic disease

D'Angelo, A., Della Valle, P., Crippa, L., Pattarini, E., Grimaldi, L. M. E. & D'Angelo, S. V., 1993, In : New England Journal of Medicine. 328, 24, p. 1753-1757 5 p.

Research output: Contribution to journalArticle

Prevention of postoperative deep vein thrombosis in cancer patients. A randomized trial with low molecular weight heparin (CY 216)

Marassi, A., Balzano, G., Mari, G., D'Angelo, S. V., Della Valle, P., Di Carlo, V. & D'Angelo, A., 1993, In : International Surgery. 78, 2, p. 166-170 5 p.

Research output: Contribution to journalArticle

1992