1989 …2019

Research output per year

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2019

Impact of pharmacological inhibition of hydrogen sulphide production in the SOD1G93A-ALS mouse model

Spalloni, A., Greco, V., Ciriminna, G., Carregari, V. C., Marini, F., Pieroni, L., Mercuri, N. B., Urbani, A. & Longone, P., May 2 2019, In : International Journal of Molecular Sciences. 20, 10, 2550.

Research output: Contribution to journalArticle

Open Access
2018

Proteomics and toxicity analysis of spinal-cord primary cultures upon hydrogen sulfide treatment

Greco, V., Spalloni, A., Carregari, V. C., Pieroni, L., Persichilli, S., Mercuri, N. B., Urbani, A. & Longone, P., Jul 10 2018, In : Antioxidants. 7, 7, 87.

Research output: Contribution to journalArticle

Tissue degeneration in ALS affected spinal cord evaluated by Raman spectroscopy

Picardi, G., Spalloni, A., Generosi, A., Paci, B., Mercuri, N. B., Luce, M., Longone, P. & Cricenti, A., Dec 1 2018, In : Scientific Reports. 8, 1, 13110.

Research output: Contribution to journalArticle

2016

MicroRNA-125b regulates microglia activation and motor neuron death in ALS

Parisi, C., Napoli, G., Amadio, S., Spalloni, A., Apolloni, S., Longone, P. & Volonte, C., Mar 1 2016, In : Cell Death and Differentiation. 23, 3, p. 531-541 11 p.

Research output: Contribution to journalArticle

2015

Evidence of hydrogen sulfide involvement in amyotrophic lateral sclerosis

Davoli, A., Greco, V., Spalloni, A., Guatteo, E., Neri, C., Rizzo, G. R., Cordella, A., Romigi, A., Cortese, C., Bernardini, S., Sarchielli, P., Cardaioli, G., Calabresi, P., Mercuri, N. B., Urbani, A. & Longone, P., Apr 1 2015, In : Annals of Neurology. 77, 4, p. 697-709 13 p.

Research output: Contribution to journalArticle

2014

Endothelin-1 is over-expressed in amyotrophic lateral sclerosis and induces motor neuron cell death

Ranno, E., D'Antoni, S., Spatuzza, M., Berretta, A., Laureanti, F., Bonaccorso, C. M., Pellitteri, R., Longone, P., Spalloni, A., Iyer, A. M., Aronica, E. & Catania, M. V., May 2014, In : Neurobiology of Disease. 65, p. 160-171 12 p.

Research output: Contribution to journalArticle

2013

Neurosteroid and neurotransmitter alterations in Parkinson's disease

Di Michele, F., Luchetti, S., Bernardi, G., Romeo, E. & Longone, P., Apr 2013, In : Frontiers in Neuroendocrinology. 34, 2, p. 132-142 11 p.

Research output: Contribution to journalArticle

Role of the N-methyl-d-aspartate receptors complex in amyotrophic lateral sclerosis

Spalloni, A., Nutini, M. & Longone, P., Feb 2013, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1832, 2, p. 312-322 11 p.

Research output: Contribution to journalArticle

2012

CREB selectively controls learning-induced structural remodeling of neurons

Middei, S., Spalloni, A., Longone, P., Pittenger, C., O'Mara, S. M., Marie, H. & Ammassari-Teule, M., Aug 2012, In : Learning and Memory. 19, 8, p. 330-336 7 p.

Research output: Contribution to journalArticle

Protein repertoire impact of Ubiquitin-Proteasome System impairment: Insight into the protective role of beta-estradiol

D'Alessandro, A., D'Aguanno, S., Cencioni, M. T., Pieroni, L., Diamantini, A., Battistini, L., Longone, P., Spalloni, A., De Laurenzi, V., Bernardini, S., Federici, G. & Urbani, A., Feb 2 2012, In : Journal of Proteomics. 75, 4, p. 1440-1453 14 p.

Research output: Contribution to journalArticle

2011

A prolonged pharmacological blockade of type-5 metabotropic glutamate receptors protects cultured spinal cord motor neurons against excitotoxic death

D'Antoni, S., Berretta, A., Seminara, G., Longone, P., Giuffrida-Stella, A. M., Battaglia, G., Sortino, M. A., Nicoletti, F. & Catania, M. V., Jun 2011, In : Neurobiology of Disease. 42, 3, p. 252-264 13 p.

Research output: Contribution to journalArticle

Increased expression of the beta3 subunit of voltage-gated Na+ channels in the spinal cord of the SOD1G93A mouse

Nutini, M., Spalloni, A., Florenzano, F., Westenbroek, R. E., Marini, C., Catterall, W. A., Bernardi, G. & Longone, P., Jun 2011, In : Molecular and Cellular Neuroscience. 47, 2, p. 108-118 11 p.

Research output: Contribution to journalArticle

Neurosteroids as neuromodulators in the treatment of anxiety disorders

Longone, P., di Michele, F., D'Agati, E., Romeo, E., Pasini, A. & Rupprecht, R., 2011, In : Frontiers in Endocrinology. 2, OCT, Article 55.

Research output: Contribution to journalArticle

The protective role of catalase against cerebral ischemia in vitro and in vivo

Armogida, M., Spalloni, A., Amantea, D., Nutini, M., Petrelli, F., Longone, P., Bagetta, G., Nisticò, R. & Mercuri, N. B., Jul 2011, In : International Journal of Immunopathology and Pharmacology. 24, 3, p. 735-747 13 p.

Research output: Contribution to journalArticle

Zinc pre-treatment enhances NMDAR-mediated excitotoxicity in cultured cortical neurons from SOD1 G93A mouse, a model of amyotrophic lateral sclerosis

Nutini, M., Frazzini, V., Marini, C., Spalloni, A., Sensi, S. L. & Longone, P., Jun 2011, In : Neuropharmacology. 60, 7-8, p. 1200-1208 9 p.

Research output: Contribution to journalArticle

2010

A systematic study of brainstem motor nuclei in a mouse model of ALS, the effects of lithium

Ferrucci, M., Spalloni, A., Bartalucci, A., Cantafora, E., Fulceri, F., Nutini, M., Longone, P., Paparelli, A. & Fornai, F., Feb 2010, In : Neurobiology of Disease. 37, 2, p. 370-383 14 p.

Research output: Contribution to journalArticle

2009

Autophagy, lithium, and amyotrophic lateral sclerosis

Pasquali, L., Longone, P., Isidoro, C., Ruggieri, S., Paparelli, A. & Fornai, F., Aug 2009, In : Muscle and Nerve. 40, 2, p. 173-194 22 p.

Research output: Contribution to journalArticle

Impaired terminal differentiation of hippocampal granule neurons and defective contextual memory in PC3/Tis21 knockout mice

Farioli-Vecchioli, S., Saraulli, D., Costanzi, M., Leonardi, L., Cinà, I., Micheli, L., Nutini, M., Longone, P., Paul Oh, S., Cestari, V. & Tirone, F., 2009, In : PLoS One. 4, 12, e8339.

Research output: Contribution to journalArticle

2008

Abnormal medial prefrontal cortex connectivity and defective fear extinction in the presymptomatic G93A SOD1 mouse model of ALS

Sgobio, C., Trabalza, A., Spalloni, A., Zona, C., Carunchio, I., Longone, P. & Ammassari-Teule, M., Jun 2008, In : Genes, Brain and Behavior. 7, 4, p. 427-434 8 p.

Research output: Contribution to journalArticle

Autophagy and amyotrophic lateral sclerosis: The multiple roles of lithium

Fornai, F., Longone, P., Ferrucci, M., Lenzi, P., Isidoro, C., Ruggieri, S. & Paparelli, A., May 16 2008, In : Autophagy. 4, 4, p. 527-530 4 p.

Research output: Contribution to journalArticle

Lithium delays progression of amyotrophic lateral sclerosis

Fornai, F., Longone, P., Cafaro, L., Kastsiuchenka, O., Ferrucci, M., Manca, M. L., Lazzeri, G., Spalloni, A., Bellio, N., Lenzi, P., Modugno, N., Siciliano, G., Isidoro, C., Murri, L., Ruggieri, S. & Paparelli, A., Feb 12 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 6, p. 2052-2057 6 p.

Research output: Contribution to journalArticle

Lithium delays progression of amyotrophic lateral sclerosis (Proceedings of the National Academy of Sciences of the United States of America (2008) 15, (2052-2057) DOI: 10.1073/pnas.0708022105)

Fornai, F., Longone, P., Cafaro, L., Kastsiuchenka, O., Ferrucci, M., Manca, M. L., Lazzeri, G., Spalloni, A., Bellio, N., Lenzi, P., Modugno, N., Siciliano, G., Isidoro, C., Murri, L., Ruggieri, S. & Paparelli, A., Oct 21 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 42, p. 16404-16407 4 p.

Research output: Contribution to journalArticle

The complex roles of neurosteroids in depression and anxiety disorders

Longone, P., Rupprecht, R., Manieri, G. A., Bernardi, G., Romeo, E. & Pasini, A., Mar 2008, In : Neurochemistry International. 52, 4-5, p. 596-601 6 p.

Research output: Contribution to journalArticle

2006

Comparative non-radioactive RT-PCR assay: An approach to study the neurosteroids biosynthetic pathway in humans

Luchetti, S., di Michele, F., Romeo, E., Brusa, L., Bernardi, G., Cummings, B. J. & Longone, P., Jun 15 2006, In : Journal of Neuroscience Methods. 153, 2, p. 290-298 9 p.

Research output: Contribution to journalArticle

P2X2R purinergic receptor subunit mRNA and protein are expressed by all hypothalamic hypocretin/orexin neurons

Florenzano, F., Viscomi, M. T., Mercaldo, V., Longone, P., Bernardi, G., Bagni, C., Molinari, M. & Carrive, P., Sep 1 2006, In : Journal of Comparative Neurology. 498, 1, p. 58-67 10 p.

Research output: Contribution to journalArticle

2005

Trace amines depress GABAB response in dopaminergic neurons by inhibiting G-βγ-gated inwardly rectifying potassium channels

Federici, M., Geracitano, R., Tozzi, A., Longone, P., Di Angelantonio, S., Bengtson, C. P., Bernardi, G. & Mercuri, N. B., Apr 2005, In : Molecular Pharmacology. 67, 4, p. 1283-1290 8 p.

Research output: Contribution to journalArticle

2004

Altered vulnerability to kainate excitotoxicity of transgenic-Cu/Zn SOD1 neurones

Spalloni, A., Pascucci, T., Albo, F., Ferrari, F., Puglisi-Allegra, S., Zona, C., Bernardi, G. & Longone, P., Dec 15 2004, In : NeuroReport. 15, 16, p. 2477-2480 4 p.

Research output: Contribution to journalArticle

Cell death in amyotrophic lateral sclerosis: Interplay between neuronal and glial cells

Ferri, A., Nencini, M., Casciati, A., Cozzolino, M., Angelini, D. F., Longone, P., Spalloni, A., Rotilio, G. & Carrì, M. T., Aug 2004, In : FASEB Journal. 18, 11, p. 1261-1263 3 p.

Research output: Contribution to journalArticle

Cellular localization of TRPC3 channel in rat brain: Preferential distribution to oligodendrocytes

Fusco, F. R., Martorana, A., Giampà, C., De March, Z., Vacca, F., Tozzi, A., Longone, P., Piccirilli, S., Paolucci, S., Sancesario, G., Mercuri, N. B. & Bernardi, G., Jul 22 2004, In : Neuroscience Letters. 365, 2, p. 137-142 6 p.

Research output: Contribution to journalArticle

2003

Altered excitability of motor neurons in a transgenic mouse model of familial amyotrophic lateral sclerosis

Pieri, M., Albo, F., Gaetti, C., Spalloni, A., Bengtson, C. P., Longone, P., Cavalcanti, S. & Zona, C., Nov 20 2003, In : Neuroscience Letters. 351, 3, p. 153-156 4 p.

Research output: Contribution to journalArticle

Altered long-term corticostriatal synaptic plasticity in transgenic mice overexpressing human Cu/Zn superoxide dismutase (Gly93→Ala) mutation

Geracitano, R., Paolucci, E., Prisco, S., Guatteo, E., Zona, C., Longone, P., Ammassari-Teule, M., Bernardi, G., Berretta, N. & Mercuri, N. B., May 8 2003, In : Neuroscience. 118, 2, p. 399-408 10 p.

Research output: Contribution to journalArticle

Decreased plasma and cerebrospinal fluid content of neuroactive steroids in Parkinson's disease

di Michele, F., Longone, P., Romeo, E., Lucchetti, S., Brusa, L., Pierantozzi, M., Bassi, A., Bernardi, G. & Stanzione, P., Oct 2003, In : Neurological Sciences. 24, 3, p. 172-173 2 p.

Research output: Contribution to journalArticle

Involvement of transient receptor potential-like channels in responses to mGluR-I activation in midbrain dopamine neurons

Tozzi, A., Bengtson, C. P., Longone, P., Carignani, C., Fusco, F. R., Bernardi, G. & Mercuri, N. B., Oct 2003, In : European Journal of Neuroscience. 18, 8, p. 2133-2145 13 p.

Research output: Contribution to journalArticle

2002

Neocortical potassium currents are enhanced by the antiepileptic drug lamotrigine

Zona, C., Tancredi, V., Longone, P., D'Arcangelo, G., D'Antuono, M., Manfredi, M. & Avoli, M., 2002, In : Epilepsia. 43, 7, p. 685-690 6 p.

Research output: Contribution to journalArticle

1999
1998

Aging-associated up-regulation of neuronal 5-lipoxygenase expression: Putative role in neuronal vulnerability

Tolga, U. Z., Pesold, C., Longone, P. & Manev, H., 1998, In : FASEB Journal. 12, 6, p. 439-449 11 p.

Research output: Contribution to journalArticle

Changes in AMPA receptor-spliced variant expression and shift in AMPA receptor spontaneous desensitization pharmacology during cerebellar granule cell maturation in vitro

Longone, P., Impagnatiello, F., Mienville, J. M., Costa, E. & Guidotti, A., 1998, In : Journal of Molecular Neuroscience. 11, 1, p. 23-41 19 p.

Research output: Contribution to journalArticle

1997

Full-length and N-terminally truncated chicken intestinal diazepam- binding inhibitor. Purification, structural characterization and influence on insulin release

Chen, Z. W., Bergman, T., Jörnvall, H., Bonetto, V., Norberg, Å., Mutt, V., Longone, P., Costa, E., Efendic, S. & Östenson, C. G., Mar 26 1997, In : Regulatory Peptides. 69, 2, p. 63-68 6 p.

Research output: Contribution to journalArticle

Increased hippocampal 5-lipoxygenase mRNA content in melatonin- deficient, pinealectomized rats

Uz, T., Longone, P. & Manev, H., Nov 1997, In : Journal of Neurochemistry. 69, 5, p. 2220-2223 4 p.

Research output: Contribution to journalArticle

1996

Modifications of γ-aminobutyric acidA receptor subunit expression in rat neocortex during tolerance to diazepam

Impagnatiello, F., Pesold, C., Longone, P., Caruncho, H., Fritschy, J. M., Costa, E. & Guidotti, A., May 1996, In : Molecular Pharmacology. 49, 5, p. 822-831 10 p.

Research output: Contribution to journalArticle

Reversible modification of GABA(A) receptor subunit mRNA expression during tolerance to diazepam-induced cognition dysfunction

Longone, P., Impagnatiello, F., Guidotti, A. & Costa, E., 1996, In : Neuropharmacology. 35, 9-10, p. 1465-1473 9 p.

Research output: Contribution to journalArticle